A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Neutrophil beta-defensin 5 is an antimicrobial peptide found in Bos taurus (Bovine), and has antibacterial activity. Synonyms: BNBD 5; Neutrophil beta-defensin 5. Grades: >98%.
Purified from freshly collected bovine plasma. The protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. No Plasmin activity is detected using chromogenic substrate S-2251. Plasminogen is activated to the serine protease plasmin via urokinase, streptokinase or tissue plasminogen activator. Group: Zymogens. Purity: >94% by SDS-PAGE. Plasminogen. Mole weight: 90,000-94,000. Stability: 30 months. Storage: 2-8°C. Source: Bovine. Bovine Plasminogen; Plasminogen. Pack: 1mg. Cat No: CZY-030.
Bovine Protein C
The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide linked heterodimer, by removal of a dipeptide (Lys-146 and Arg-147) from the precursor molecule. Trace quantities of the single chain form have been observed in plasma. The light chain, which is responsible for the calcium dependent binding of protein C to phospholipid vesicles, contains 11 γ-carboxyglutamic acid (gla) residues, 1 b-hydroxyaspartic acid residue, and 2 epidermal growth factor (EGF) homology domains. The serine protease catalytic triad is located in the heavy chain. Human protein C is susceptible to proteolytic cleavag...g the proteolytic inactivation of factors Va and VIIIa. APC also contributes to the fibrinolytic response by complex formation with plasminogen activator inhibitors.Bovine protein C is prepared from fresh citrated bovine plasma by a modification of the Walker procedure, as described by Haley et al. Human protein C is prepared from fresh frozen citrated human plasma using a combination of immunoaffinity chromatography, and conventional techniques. Protein C is provided in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a chromogenic substrate based assay. Group: Zymogens. Purity: >95% by SDS-PAGE. Prote
Bovine Prothrombin
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature p...Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20
Bovine Serum Albumin
100g Pack Size. Group: Amino Acids, Analytical Reagents, Biochemicals. Formula: N/A. CAS No. 9048-46-8. Prepack ID 22574477-100g. See USA prepack pricing.
Bovine Serum Albumin
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Albumin bovine serum; BSA. CAS No. 9048-46-8. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0842.
Bovine Serum Albumin (Low Endotoxin,Fatty acid free)
Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) is a 583 amino acid globular protein and oligonucleotide binding protein composed of three homologous full ? domains. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) blocks the overall binding of oligonucleotides to cells. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) regulates the development of hamster embryos and induces arthritis[1][2][3][4]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Albumin bovine serum (Low Endotoxin,Fatty acid free); BSA (Low Endotoxin,Fatty acid free). CAS No. 9048-46-8. Pack Sizes: 1 g; 5 g. Product ID: HY-D0842A.
Bovine Serum Albumin solution
35% in DPBS, sterile-filtered, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Bovine Serum Protein Concentrate Powder
Bovine Serum Protein Concentrate Powder.
CA, FL & NJ
Bovine Spleen Substance Powder
Bovine Spleen Substance Powder.
CA, FL & NJ
Bovine Superoxide dismutase-polyethylene glycol
Superoxide dismutases (SOD) are enzymes that alternately catalyze the dismutation (or partitioning) of the superoxide (O2-) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2-). Group: Enzymes. Synonyms: PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. SOD. Activity: 11,000 units/mg SOD before conjugation; SOD/PEG ratio: 10-20 PEG with each SOD enzyme. Appearance: Off-white. Storage: Store at -20°C. Form: Lyophilized powder. Source: Bovine Kidney. Species: Bovine. PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. Cat No: NATE-0682.
Bovine tendon powder
Bovine tendon powder. Group: Natural polymers and biopolymers. CAS No. 9007-34-5.
Bovine Thymus Powder Thymomodulin 99% HPLC
Bovine Thymus Powder Thymomodulin 99% HPLC.
CA, FL & NJ
Bovine Thymus Substance Powder
Bovine Thymus Substance Powder.
CA, FL & NJ
Bovine Thyroid Freeze Dried Powder
Bovine Thyroid Freeze Dried Powder.
CA, FL & NJ
Bovine Thyroid Thyroxin Free Powder
Bovine Thyroid Thyroxin Free Powder.
CA, FL & NJ
Bovinocidin
Bovinocidin is a fatty acid derivative produced by Streptomyces sp., Aspergillus avenaceus, Asp. flavust, Asp. oryzae and Penicillum atrovenetum. The minimum inhibitory concentration for BCG tuberculosis (BCG) is 50-100 ?/mL. Uses: Antihypertensive agents. Synonyms: Hiptagenic acid. Grades: >98%. CAS No. 504-88-1. Molecular formula: C3H5NO4. Mole weight: 119.08.
Box5
Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma [1]. Uses: Scientific research. Group: Peptides. CAS No. 1206604-29-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123071.
Boxazomycin A
Boxazomycin A is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. Synonyms: 4-Benzoxazolecarboxamide, 5-hydroxy-2-(5-hydroxy-2-(hydroxymethyl)-4-pyrimidinyl)-7-methyl-; (2Z)-5-hydroxy-2-[2-(hydroxymethyl)-5-oxopyrimidin-4-ylidene]-7-methyl-3H-1,3-benzoxazole-4-carboxamide. CAS No. 107021-64-7. Molecular formula: C14H12N4O5. Mole weight: 316.27.
Boxazomycin B
Boxazomycin B is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. CAS No. 107021-65-8. Molecular formula: C14H12N4O4. Mole weight: 300.27.
Boxazomycin C
Boxazomycin C is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. CAS No. 107021-66-9. Molecular formula: C14H12N4O4. Mole weight: 300.27.
BP-1-102
BP-1-102 is an orally available, small-molecule inhibitor of transcription factor Stat3, with an IC50 of 6.8 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334493-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-100493.
BP-1-102
BP-1-102 is a potent and selective STAT3 inhibitor. BP-1-102 inhibits the expression of genes including c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and Krüppel-like factor 8, which is related to the STAT3-mediated breast tumor growth and migration. Synonyms: 4-(N-(4-cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid. Grades: >98%. CAS No. 1334493-07-0. Molecular formula: C29H27F5N2O6S. Mole weight: 626.595.
BP4mPy
BP4mPy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 33'55'-Tetra[(m-pyridyl)-phen-3-yl]biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1009033-94-6. Molecular formula: C56H38N4. Mole weight: 766.93 g/mol. Product ID: ACM1009033946. Alfa Chemistry ISO 9001:2015 Certified.
Bp 554 maleate
Bp 554 maleate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tocris-0556, Biomol-NT_000106, BPBio1_001399, BP 554, BP-554, CID134117, NCGC00024650-01, NCGC00024650-02, L003497, BRD-K45479396-001-01-8, 1-(3-(3,4-Methylenedioxyphenoxy)propyl)-4-phenylpiperzine, 1-[3-(1,3-Benzodioxol-5-yloxy)propyl]-4-phenylpiperazine, 1-[3-3,4-Methylenedioxyphenoxy;propyl]-4-phenylpiperazine, Piperazine, 1-(3-(1,3-benzodioxol-5-yloxy)propyl)-4-phenyl-, 82900-57-0. Product Category: Heterocyclic Organic Compound. CAS No. 82900-57-0. Molecular formula: C20H24N2O3.C4H4O4. Mole weight: 456.49. Purity: >99 %. IUPACName: 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenylpiperazine. Canonical SMILES: C1CN(CCN1CCCOC2=CC3=C(C=C2)OCO3)C4=CC=CC=C4. Density: 1.188g/cm³. Product ID: ACM82900570. Alfa Chemistry ISO 9001:2015 Certified.
BP 554 maleate
BP 554 maleate is a selective 5-HT1A agonist. Synonyms: Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-, (2Z)-2-butenedioate (1:1); 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine maleate; 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenylpiperazine maleate. Grades: ≥99% by HPLC. CAS No. 1221401-95-1. Molecular formula: C20H24N2O3.C4H4O4. Mole weight: 456.48.
BP 554 maleate
BP 554 maleate. Group: Biochemicals. Grades: Purified. CAS No. 1221401-95-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
BPAPF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9-Bis[4-(N,N-bis-biphenyl-4-yl-amino)phenyl]-9H-fluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 174141-92-5. Molecular formula: C73H52N2. Mole weight: 957.21 g/mol. Product ID: ACM174141925. Alfa Chemistry ISO 9001:2015 Certified. Categories: BPAP machine.
BPBPA
BPBPA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4,N4,N4',N4'-Tetra[(1,1'-biphenyl)-4-yl]-(1,1'-biphenyl)-4,4'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 164724-35-0. Molecular formula: C60H44N2. Mole weight: 793 g/mol. Product ID: ACM164724350-3. Alfa Chemistry ISO 9001:2015 Certified. Categories: BPB Partecipazioni.
BPC 157
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 137525-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105174.
BPC 157
BPC-157 is a synthetic pentadecapeptide. Study shows that BPC-157 is beneficial for the treatment of ulcers in the stomach, intestinal damage such as fistulas and inflammatory disorders, bone and joint healing and growth rates, and organ damage. Synonyms: BPC 157; BPC157; Glycyl-L-α-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-α-aspartyl-L-α-aspartyl-L-alanylglycyl-L-leucyl-L-valine. CAS No. 137525-51-0. Molecular formula: C62H98N16O22. Mole weight: 1419.54.
BPC 157 acetate
BPC 157 acetate is a synthetic pentadecapeptide that is beneficial for the treatment of ulcers in the stomach, intestinal damage such as fistulas and inflammatory disorders, bone and joint healing and growth rates, and organ damage. Synonyms: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH.CH3CO2H; glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolyl-glycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanyl-glycyl-L-leucyl-L-valine acetic acid. Grades: ≥95%. CAS No. 216441-37-1. Molecular formula: C64H102N16O24. Mole weight: 1479.61.
BPDBA is a selective and noncompetitive betaine/GABA transporter ( BGT-1 ) inhibitor with IC 50 s of 20 μM and 35 μM against human BGT-1 and mouse GAT2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312281-74-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119591.
BPD-Ring B
BPD-Ring B is a product from the synthesis of verteporfinin. It can be used for making porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic drugs. Uses: Make porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic drugs. Synonyms: BPD-B; Benzoporpyrin Ring B derivative;23H,25H-Benzo[b]porphine-9,13- dipropanoic acid, 19-ethenyl-1,22a-dihydro-1,2-bis(methoxycarbonyl)-8,14,18, 22a-tetramethyl-, dimethyl ester. Grades: 98%. CAS No. 143986-17-8. Molecular formula: C42H44N4O8. Mole weight: 732.83.
BPH-652
BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections. Synonyms: BMS-187745; BPH-652; BMS 187745; BPH 652; BMS187745; BPH652; CHEMBL351151; BMS 188745 Potassium Salt; DNC009027; KB-75764; tripotassium;4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate. Grades: 98%. CAS No. 157124-84-0. Molecular formula: C16H16K3O7PS. Mole weight: 500.63.
BPH715
BPH715 is a new generation of lipophilic bisphosphonates. It is potent in cell culture and effectively inhibited tumor cell growth and invasiveness. It is used as anticancer agents that block protein prenylation also have potent activity against Plasmodium liver stages. It has activity against a Plasmodium geranylgeranyl diphosphate synthase (GGPPS), as well as low nM activity against human farnesyl and geranylgeranyl diphosphate synthases. It is used to treat bone resorption diseases and has activity against a broad range of protists, including blood-stage Plasmodium spp. Uses: Bph715 is used as anticancer agents that block protein prenylation also have potent activity against plasmodium liver stages. it is also used to treat bone resorption diseases and has activity against a broad range of protists. Synonyms: BPH-715; BPH 715; BPH715; GTPL3196; GTPL 3196; GTPL-3196; Bisphpshonate-715. 3-(Decyloxy)-1-(2-hydrogen phosphonato-2-phosphonoethyl)pyridin-1-ium;Bisphpshonate-715;[2-(3-Decoxypyridin-1-ium-1-yl)-1-phosphonoethyl]-hydroxyphosphinate;Hydrogen (2-(3-(decyloxy)pyridin-1-ium-1-yl)-1-phosphonoethyl)phosphonate. Grades: >98%. CAS No. 1059677-23-4. Molecular formula: C17H31NO7P2. Mole weight: 423.38.
BPHA
BPHA is a potent and orally active MMP-2 , MMP-9 and MMP-14 inhibitor with IC 50 s of 12 nM, 16 nM and 17 nM, respectively. BPHA does not inhibit MMP-1, -3, and -7 (the IC 50 s are 974, >1000, and 795 nM, respectively). BPHA has antiangiogenic and antitumor effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193807-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114785.
Bphen
Bphen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 47-Diphenyl-110-phenanthroline. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1662-01-7. Molecular formula: C24H16N2. Mole weight: 332.4 g/mol. Product ID: ACM1662017-4. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4,7-Diphenyl-1,10-phenanthroline, B-Phenethylamine.
B-Phycoerythrin, activated
BioReagent, suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
BPI-3016
BPI-3016 is an analogue of human glucagon-like peptide 1 (hGLP-1) that has a long effect on type 2 diabetes mellitus. In vitro, BPI-3016 exhibited an affinity to GLP receptors and promotes cAMP production. In vivo, the half-life of BPI-3016 was 95h after single dosing in pharmacokinetic studies in diabetic cynomolgus monkey models. Uses: The treatment of type 2 diabetes. Synonyms: BPI-3016; BPI 3016; BPI3016.
BPI-9016M
BPI-9016M is a potent, orally active, and selective dual c-Met and AXL tyrosine kinases inhibitor. BPI-9016M suppresses tumor cell growth, migration and invasion of lung adenocarcinoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1528546-94-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114356.
bPiDDB
bPiDDB is a potent nAChR antagonist. bPiDDB potently ( IC 50 =2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 525596-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107674.
bPiDDB
bPiDDB. Group: Biochemicals. Grades: Purified. CAS No. 525596-66-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
BPIPP. Group: Biochemicals. Grades: Purified. CAS No. 325746-94-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BPIPP
BPIPP is a non-competitive guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor. It downregulates cAMP and cGMP synthesis, suppresses cGMP accumulation in a variety of cell lines (IC50 = 3.4 - 11.2 μM), inhibits GC-stimulated Cl- transport in vitro, and suppresses toxin-induced intestinal fluid accumulation in vivo. BPIPP may be a useful treatment of diarrhea. Uses: Potential treatment of diarrhea. Synonyms: 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione. Grades: ≥99% by HPLC. CAS No. 325746-94-9. Molecular formula: C22H16BrN3O3. Mole weight: 450.28.
BPIQ-I
BPIQ-I is an extremely potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) with IC50 of 25 pM. It can inhibit the growth of SKOV3 and MDA-468 tumor cell lines with EC50 values of 6.5 and 30 μM, respectively. Uses: Protein kinase inhibitors. Synonyms: PD 159121. Grades: ≥95%. CAS No. 174709-30-9. Molecular formula: C16H12BrN5. Mole weight: 354.2.
BPIQ-II hydrochloride
BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) with IC50 of 8 pM. It is selective for EGFR over an assortment of other tyrosine and serine/threonine kinases. Cellular studies indicate that BPIQ-II can enter cells and very selectively shut down EGF-stimulated signal transmission by binding competitively at the ATP site of EGFR. Synonyms: PD 158294. Grades: ≥98%. CAS No. 171179-37-6. Molecular formula: C15H10BrN5·HCl. Mole weight: 376.6.
BPK-25
BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305052-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141550.
Bpl I, SAM, 50X. Group: Molecular Biology. Grades: Molecular Biology Grade. Pack Sizes: 1x100ul. US Biological Life Sciences.
Worldwide
BpmI
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme about 95% of the dna fragments can be ligated and 95% may be recut. Group: Restriction Enzymes. Purity: 50U; 250U. CTGGAG(N)16↑ GACCTC(N)14&darr. Activity: 500-1000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus pumilus. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1038RE.
BPO-27 racemate is a potent CFTR inhibitor with an IC 50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314873-02-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-19778A.
BPO-27 racemate
BPO-27 racemate inhibited CFTR with IC50 ? 8 nM and had greatly improved in vitro metabolic stability and aqueous solubility compared to PPQ-102. Synonyms: BPO-27 (racemate); BPO 27 racemate; BPO27 racemate; BPO-27 racemate; CHEMBL1831075; CHEMBL 1831075; CHEMBL-1831075; BPO-27 racemat. CAS No. 1314873-02-3. Molecular formula: C26H18BrN3O6. Mole weight: 548.34.
BPOPB
BPOPB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3-Bis(3-(diphenylphosphoryl)phenyl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1863083-31-1. Molecular formula: C42H32O2P2. Mole weight: 630.65 g/mol. Product ID: ACM1863083311. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bpoplive.
BP-OXD-Bpy
BP-OXD-Bpy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6,6'-Bis[5-(biphenyl-4-yl)-1,3,4-oxadiazo-2-yl]-2,2'-bipyridyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1219827-28-7. Molecular formula: C38H24N6O2. Mole weight: 596.64 g/mol. Product ID: ACM1219827287. Alfa Chemistry ISO 9001:2015 Certified.
BPPF
BPPF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9-Bis[4-(pyrenyl)phenyl]-9H-fluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1174006-47-3. Molecular formula: C57H34. Mole weight: 718.88 g/mol. Purity: 95%+. IUPACName: 1-[4-[9-(4-pyren-1-ylphenyl)fluoren-9-yl]phenyl]pyrene. Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C2(C4=CC=C(C=C4)C5=C6C=CC7=CC=CC8=C7C6=C(C=C8)C=C5)C9=CC=C(C=C9)C1=C2C=CC3=CC=CC4=C3C2=C(C=C4)C=C1. Product ID: ACM1174006473. Alfa Chemistry ISO 9001:2015 Certified.
BPR1J-097
BPR1J-097 is a novel potent FLT3 inhibitor with an IC50 of 11?nM. Synonyms: BPR1J097; BPR1J-097; BPR1J 097; BPR1-J097; BPR1 J097; BPR1J097. Grades: >98%. CAS No. 1327167-19-0. Molecular formula: C27H28N6O3S. Mole weight: 516.62.
BPR1J-340
BPR1J-340 is a potent and selective FLT3 inhibitor with potential anticancer activity. BPR1J-340 was identified as a novel potent FLT3 inhibitor by biochemical kinase activity (IC50 approximately 25 nM) and cellular proliferation (GC50 approximately 5 nM) assays. BPR1J-340 inhibited the phosphorylation of FLT3 and STAT5 and triggered apoptosis in FLT3-ITD(+) AML cells. The pharmacokinetic parameters of BPR1J-340 in rats were determined. BPR1J-340 also demonstrated pronounced tumor growth inhibition and regression in FLT3-ITD(+) AML murine xenograft models. The combination treatment of the HDAC inhibitor vorinostat (SAHA) with BPR1J-340 synergistically induced apoptosis via Mcl-1 down-regulation in MOLM-13 AML cells, indicating that the combination of selective FLT3 kinase inhibitors and HDAC inhibitors could exhibit clinical benefit in AML therapy. Synonyms: BPR1J 340; BPR1J340. Grades: 98%. CAS No. 1395051-72-5. Molecular formula: C29H34N8O3. Mole weight: 542.63.