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| Product | Description | |
|---|---|---|
| Brass gauze, alloy 260, 80 mesh woven from 0.14mm (0.0055in) dia wire; Cu:Zn; 70:30 wt% | Brass gauze, alloy 260, 80 mesh woven from 0.14mm (0.0055in) dia wire; Cu:Zn; 70:30 wt%. Group: Alloys. |  |
| Brassicasterol | Brassicasterol. Group: Biochemicals. Alternative Names: (3b,22E)-Ergosta-5,22-dien-3-ol; Ergosta-5,22-dien-3b-ol; 24(R)-Methylcholesta-5,22E-dien-3b-ol. Grades: Highly Purified. CAS No. 474-67-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C28H46O. US Biological Life Sciences. |  Worldwide |
| Brassicasterol | from semisynthetic. Group: Fluorescence/luminescence spectroscopy. |  |
| Brassicasterol | A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. Brassicasterol can increase accumulation of demosterol, a cholesterol precursor and substrate and inhibit cholesterol formation in HL-60 cells in a dose-dependent manner. It also inhibits the hemolytic activity of pneumolysin from S. pneumoniae. Synonyms: (3β,22E)-Ergosta-5,22-dien-3-ol; 24-Methylcholesta-5,22-dien-3β-ol; Brassicasterin; Ergosta-5,22(E)-dien-3β-ol. Grades: ≥95%. CAS No. 474-67-9. Molecular formula: C28H46O. Mole weight: 398.66. |  |
| Brassicasterol | Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 ( IC 50 =1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase , slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 474-67-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113289. |  |
| Brassicasterol | Brassicasterol, a metabolite of Ergosterol, plays a role in the inhibitory effect on bladder carcinogenesis promotion via androgen signaling. Brassicasterol shows dual anti-infective properties against HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis, and cardiovascular protective effect. Brassicasterol exerts an anti-cancer effect by dual-targeting AKT and androgen receptor signaling in prostate cancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ergosta-5,22E-dien-3beta-ol; (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(E,1R,4R)-1,4,5-trimethylhex-2-enyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Product Category: Inhibitors. Appearance: Cryst. CAS No. 474-67-9. Molecular formula: C28H46O. Mole weight: 398.66. Purity: 0.98. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Product ID: ACM474679-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Brassicasterol-(2,2',3,4,4',6-D6) | Brassicasterol-(2,2',3,4,4',6-D6) is derived from Brassicasterol (B676850), which is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H40D6O, Molecular Weight: 404.7. US Biological Life Sciences. | Worldwide |
| Brassinazole | Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 280129-83-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-121161A. | |
| Brassinazole | Brassinazole is a potent brassinosteroid (BR) biosynthesis inhibitor that has similar structure to pacrobutrazol. Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. It has displayed the ability to induce morphological changes in dark-grown Arabidopsis. It can also induce morphological changes, including dwarfism and altered leaf color and curling. Synonyms: Brassinazole. Grades: ≥98%. CAS No. 224047-41-0. Molecular formula: C18H18ClN3O. Mole weight: 327.8. | |
| Brassinin | Brassinin. Group: Biochemicals. Alternative Names: N- (1H-Indol-3-ylmethyl) carbamodithioic acid. Grades: Highly Purified. CAS No. 105748-59-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H12N2S2. US Biological Life Sciences. | Worldwide |
| Brassinin | Brassinin is the metabolism of a phytoalexin from Beassica pekinensis (Lour. ) Rupr. [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Brassinine. CAS No. 105748-59-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-111334. | |
| Brassinin | Brassinin is an inhibitor of indoleamine 2,3-dioxygenase (IDO; Ki = 28 μM for human IDO) with antifungal and anticancer activities. Brassinin also inhibits IL-6-inducible STAT3 activation and attenuates tumor growth in a xenograft lung cancer mouse model. Brassinin is found in brassicas. Synonyms: Brassinine; CCG-208623; CCG208623; CCG 208623; HE-005916; HE005916; HE 005916; HE-292778; HE292778; HE292778; Methyl (1H-indol-3-ylmethyl)carbamodithioate. Grades: 98%. CAS No. 105748-59-2. Molecular formula: C11H12N2S2. Mole weight: 236.36. | |
| Brassinin | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Brassinin | Brassinin is an indoleamine-2,3-dioxygenase inhibitor found in cruciferous vegetables. It induces cell cycle arrest and apoptosis in prostate cancer cells and inhibits DMBA-induced skin tumor formation in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Brassinine; CCG-208623; CCG208623; CCG 208623; HE-005916; HE005916; HE 005916; HE-292778; HE292778; HE292778. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 105748-59-2. Molecular formula: C11H12N2S2. Mole weight: 236.35. Purity: >98%. IUPACName: methyl ((1H-indol-3-yl)methyl)carbamodithioate. Canonical SMILES: S=C(SC)NCC1=CNC2=C1C=CC=C2. Product ID: ACM105748592-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Brassinolide | 25mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C28H48O6. CAS No. 72962-43-7. Prepack ID 90026901-25mg. Molecular Weight 480.68. See USA prepack pricing. |  |
| Brassinolide | 5mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C28H48O6. CAS No. 72962-43-7. Prepack ID 90026901-5mg. Molecular Weight 480.68. See USA prepack pricing. | |
| Brassinolide | Brassinolide is a predominant plant growth modulator that regulate plant cell elongation. Uses: Scientific research. Group: Natural products. Alternative Names: Brassin lactone. CAS No. 72962-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0273. | |
| Brass plate, alloy 260, 2.4mm (0.093in) thick | Brass plate, alloy 260, 2.4mm (0.093in) thick. Group: Alloys. | |
| Brass plate, alloy 260, 3.18mm (0.125in) thick | Brass plate, alloy 260, 3.18mm (0.125in) thick. Group: Alloys. Molecular formula: 336g/mol. Mole weight: CuPbZn. [Cu].[Zn].[Pb]. InChI=1S/Cu.Pb.Zn. UXNBTDLSBQFMEH-UHFFFAOYSA-N. | |
| Brass plate alloy 260, 6.35mm (0.25in) thick | Brass plate alloy 260, 6.35mm (0.25in) thick. Group: Alloys. | |
| Brass spheres, alloy 260, 12.7mm (0.5in) dia | Brass spheres, alloy 260, 12.7mm (0.5in) dia. Group: Alloys. Molecular formula: 336g/mol. Mole weight: CuPbZn. [Cu].[Zn].[Pb]. InChI=1S/Cu.Pb.Zn. UXNBTDLSBQFMEH-UHFFFAOYSA-N. | |
| Brass spheres, alloy 260, 3.18mm (0.125in) dia | Brass spheres, alloy 260, 3.18mm (0.125in) dia. Group: Alloys. | |
| Brass spheres, alloy 260, 6.35mm (0.25in) dia | Brass spheres, alloy 260, 6.35mm (0.25in) dia. Group: Alloys. | |
| Brazikumab | Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23 , with a K D of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 139; MEDI2070. CAS No. 1610353-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99485. | |
| Brazilin | Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis , and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 474-07-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0072. | |
| Brazilin | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Brazilin (Brasilin) | Brazilin (Brasilin). Group: Biochemicals. Grades: Plant Grade. CAS No. 474-07-7. Pack Sizes: 10mg. Molecular Formula: C16H14O5, Molecular Weight: 286.28. US Biological Life Sciences. | Worldwide |
| BrBzGCp2 | BrBzGCp2 is a Glyoxalase 1 (GLO1) inhibitor, with a GC50 of 4.23 ?M in HL-60 cells. BrBzGCp2 possesses antitumor and neuroprotective activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-p-Bromobenzylglutathione cyclopentyl diester. CAS No. 166038-00-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136684. | |
| BRCA1 human | recombinant, expressed in insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRCA1-IN-1 | A novel small-molecule-like BRCA1 inhibitor (IC50= 0.53 μM) (Ki= 0.71 μM). Synonyms: [ (3S) -1, 1-difluoro-3-[3- (1H-indol-3-yl) propanoylamino]-4-oxo-4-[[2-oxo-2- (4-phenylbutylamino) ethyl]amino]butyl]phosphonic acid. CAS No. 1622262-74-1. Molecular formula: C27H33F2N4O6P. Mole weight: 578.54. | |
| BRD0639 | BRD0639 is a potent PRMT5 inhibitor. BRD0639 engages the target in cells, disrupts PRMT5-RIOK1 complexes, and reduces substrate methylation. BRD0639 is a first-in-class PBM-competitive inhibitor that can support studies of PBM-dependent PRMT5 activities and the development of novel PRMT5 inhibitors that selectively target these functions. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BRD0639; BRD 0639; BRD-0639. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2760881-74-9. Molecular formula: C21H22ClN5O4S. Mole weight: 475.95. Purity: >98%. IUPACName: (S)-2-(4-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-(N-(2-(pyridin-2-yl)ethyl)sulfamoyl)phenyl)propanamide. Canonical SMILES: C[C@H](N1C(C=C(Cl)C=N1)=O)C(NC2=CC=C(C)C(S(=O)(NCCC3=NC=CC=C3)=O)=C2)=O. Product ID: ACM2760881749. Alfa Chemistry ISO 9001:2015 Certified. | |
| BRD0705 | BRD0705 is a potent, paralog selective and orally active GSK3? inhibitor with an IC50 of 66 nM and a Kd of 4.8 ?M. BRD0705 displays increased selectivity for GSK3? (8-fold) versus GSK3? (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML) research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2056261-41-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116830. | |
| BRD1 (561-668) GST tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD1 (561-668) His tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD2 (339-459) GST tag human | recombinant, expressed in E. coli, ?86% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD2 (339-459) His tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD2 (65-187) GST tag human | recombinant, expressed in E. coli, ?81% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD2 (65-187) His tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD2, BD1, BD2 (65-459) GST tag human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD2 Inhibitor II, BIC1 (BRD2 Bromodomain-Interactive Compound, BIC1, 1-(2-(1H-Benzimidazol-2-ylsulfanyl)ethyl)-3-methyl-1,3-dihydro-2H-benzimidazole-2-thione, 1-(2-(1H-Benzo[d]imidazol-2-ylthio)ethyl)-3-methyl-1H-benzo[d]imidazole-2(3H)-thione) | A cell-permeable benzimidazolyl-benzimidazolothione compound that directly interacts with BRD2-BD1 bromodomain reversibly (=28uM) and blocks the transcriptional activity of BRD2 in COS7 cells expressing Histac-K12 (<10uM). Shown to selectively disrupt BRD2 bromodomain-acetylated histone H4K12 association without modulating H4K12 acetylation; only weakly affect the interaction between the BRDT bromodomain (testis-specific bromodomain-containing protein) and acetylated histone H4. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BRD32048 | The ETV1 transcription factor is phosphorylated downstream of MAPK signaling and is acetylated at lysines 33 and 116 by the histone acetyltransferase p300. BRD32048 is an inhibitor of the ETV1 transcription factor oncoprotein. BRD32048 binds ETV1 directly, modulating both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 is a substituted [1,3,5]triazine derivative that inhibits ETV1 transcriptional activity by binding to ETV1 with KD of 17.1 μM, which reduces p300-dependent acetylation and stability of ETV1. Synonyms: BRD-32048; BRD 32048. Grades: ≥98%. CAS No. 433694-46-3. Molecular formula: C16H22N6O. Mole weight: 314.4. | |
| BRD32048 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BRD3 (29-145) GST tag human | recombinant, expressed in E. coli, ?81% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD3 (29-145) His tag human | recombinant, expressed in E. coli, ?88% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD3 (306-417) GST tag human | recombinant, expressed in E. coli, ?82% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD3 (306-417) His tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD3308 | BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23-fold selectivity for HDAC3 over HDAC1 (IC50 of 1.26 ?M) or HDAC2 (IC50 of 1.34 ?M). BRD3308 suppresses pancreatic ?-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. BRD3308 activates HIV-1 transcription and disrupts HIV-1 latency[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1550053-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19618. | |
| BRD3308 | BRD3308 is a highly selective HDAC3 inhibitor with IC50 of 54 nM. BRD3308 inhibits pancreatic β-cell apoptosis induced by inflammatory cytokines or glycolipid toxic stress, and increases the release of functional insulin. BRD3308 activates HIV-1 transcription and destroys the HIV-1 incubation period. Synonyms: 4-Acetylamino-N-(2-Amino-4-Fluorophenyl)-Benzamide; CHEMBL4293858; SCHEMBL15551809; BDBM178100. Grades: 98%. CAS No. 1550053-02-5. Molecular formula: C15H14FN3O2. Mole weight: 287.29. | |
| BRD3308 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4 (342-460) GST tag human | recombinant, expressed in E. coli, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4 (342-460) His tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4354 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BRD 4354 | BRD 4354 is an HDAC5 and HDAC9 inhibitor (IC50 = 0.85 and 1.88 μM, respectively) displaying >20-fold selectivity for HDAC5/9 over HDAC1/2/3. It also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM). Synonyms: BRD4354; BRD 4354; BRD-4354; 5-Chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-8-quinolinol. Grades: ≥98% by HPLC. CAS No. 315698-07-8. Molecular formula: C21H23ClN4O. Mole weight: 382.89. | |
| BRD4 (49-170) GST tag human | recombinant, expressed in E. coli, ?82% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4 (49-170) His tag human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4770 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4770 | BRD4770 is a novel histone methyltransferase inhibitor. BRD4770 reduced cellular levels of di- and trimethylated H3K9 without inducing apoptosis, induced senescence, and inhibited both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1. ATM-pathway activation, caused by either genetic or small-molecule inhibition of G9a, may mediate BRD4770-induced cell senescence. BRD4770 may be a useful tool to study G9a and its role in senescence and cancer cell biology. Synonyms: BRD4770; BRD-4770; BRD 4770. Grades: 0.98. CAS No. 1374601-40-7. Molecular formula: C25H23N3O3. Mole weight: 413.477. | |
| BRD4884 | BRD4884 is a selective HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 μM for HDAC1, 2, and 3. It possesses preferential binding kinetics with seven-fold longer half-life. BRD4884 crosses the blood brain barrier and has been evaluated in CK-p25 mice, a mouse model of neurodegeneration. It acts by enhancing the learning and memory processes. Synonyms: BRD-4884; BRD 4884. Grades: ≥98%. CAS No. 1404559-91-6. Molecular formula: C18H19FN2O2. Mole weight: 314.4. | |
| BRD4, BD1, BD2 (49-460) GST tag human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4, BD1, BD2 (49-460) His tag human | recombinant, expressed in E. coli, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRD4 degrader-3 | BRD4 degrader-3 is a potent bromodomain BRD4 degrader extracted from patent WO2020055976A1, example 1a, has IC 50 s of 15.5 and 12.3 nM for BRD4-BD1 and BRD4-BD2, respectively [1]. PROTAC BRD4 Degrader-7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413382-30-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136857. | |
| BRD4-IN-4 | BRD4-IN-4 (Compound 1) is a BRD4 inhibitor ( IC 50 =6.83 μM). BRD4-IN-4 selectively inhibits MV4-11 cell line proliferation and arrests cell at G1 phase. BRD4-IN-4 can be used for research of MLL leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304685-40-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153751. | |
| BRD4 ligand 6 TFA | BRD4 ligand 6 TFA is the TFA salt form of BRD4 ligand 6 (HY-161651). BRD4 ligand 6 TFA is a BRD4 ligand and can be used for synthesis of BRD4 PROTACs, such as PROTAC BRD4 Degrader-26 (HY-161650) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763548-61-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161651A. | |
| BRD5529 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BRD5529 | BRD5529 is an effective dose-dependent CARD9-TRIM62 protein-protein interaction (PPI) inhibitor with an IC50 value of 8.6 ?M. BRD5529 has potency and complete inhibition of CARD9 ubiquitinylation in vitro, also has favorable solubility. BRD5529 can be used for the research of inflammatory bowel disease (IBD) such as Crohns disease (CD) and ulcerative colitis (UC)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1358488-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115497. | |
| BRD56491 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BRD6688 | BRD6688 is an HDAC inhibitor with IC50 values of 21 nM, 100 nM, and 11.48 μM for HDAC1, 2, and 3, respectively. It possesses preferential binding kinetics with six-fold extended half-life on HDAC2 compared to HDAC1. It crosses the blood brain barrier and has been shown to rescue the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model of neurodegeneration. Synonyms: BRD-6688; BRD 6688. Grades: ≥98%. CAS No. 1404562-17-9. Molecular formula: C16H18N4O. Mole weight: 282.3. | |
| BRD-6929 | BRD-6929 is a potent, selective brain-penetrant inhibitor of class I histone deacetylase HDAC1 and HDAC2 inhibitor with IC50 of 1 nM and 8 nM, respectively. BRD-6929 shows high-affinity to HDAC1 and HDAC2 with Ki of 0.2 and 1.5 nM, respectively. BRD-6929 can be used for mood-related behavioral model research[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 849234-64-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100719. | |
| BRD6989 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BRD 6989 | BRD 6989 is a small molecule inhibitor with high selectivity for CDK8 over CDK19. It is an analog of the natural product cortistatin A (dCA), which inhibits CDK8 and upregulates IL-10. BRD 6989 selectively binds a complex of CDK8 with an IC50 of 200 nM. It also inhibits IFNγ-induced phosphorylation of STAT1 at Ser 727 site in BMDCs. It may be useful for inflammatory disorders. Synonyms: 2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile; BRD-6989; BRD6989. Grades: ≥98%. CAS No. 642008-81-9. Molecular formula: C16H16N4. Mole weight: 264.33. | |
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