A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Bosutinib Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6,7-dimethoxyquinoline-3-carbonitrile. CAS No. 380843-12-9. Molecular Formula: C19H15Cl2N3O3. Mole Weight: 404.25. Catalog: APB380843129.
Bosutinib Impurity 50
Bosutinib Impurity 50. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H34Cl3N5O4. Mole Weight: 586.94. Catalog: APB07028.
Bosutinib Impurity 53
Bosutinib Impurity 53. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H29Cl2N5O4. Mole Weight: 546.45. Catalog: APB07030.
Bosutinib Impurity 54
Bosutinib Impurity 54. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H28Cl2N6O4. Mole Weight: 559.45. Catalog: APB07031.
Bosutinib Impurity 55
Bosutinib Impurity 55. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H26Cl2N6O4. Mole Weight: 545.42. Catalog: APB07032.
Bosutinib Impurity 59
Bosutinib Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H20Cl3N3O4. Mole Weight: 484.76. Catalog: APB07033.
Bosutinib Impurity 6
Bosutinib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((2,4-dichloro-5-methoxyphenyl)amino)-7-(3-hydroxypropoxy)-6-methoxyquinoline-3-carbonitrile. Molecular Formula: C21H19Cl2N3O4. Mole Weight: 448.30. Catalog: APB03813.
Bosutinib Impurity 7
Bosutinib Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carboxamide. Molecular Formula: C26H31Cl2N5O4. Mole Weight: 548.46. Catalog: APB03812.
Bosutinib Impurity 8
Bosutinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carboxylic acid. Molecular Formula: C26H30Cl2N4O5. Mole Weight: 549.45. Catalog: APB03810.
Bosutinib Impurity 9
Bosutinib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-((2,4-dichloro-5-hydroxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile. CAS No. 2468737-92-8. Molecular Formula: C25H27Cl2N5O3. Mole Weight: 516.42. Catalog: APB2468737928.
Bosutinib Isomer
Bosutinib Isomer is an isomer of Bosutinib. Synonyms: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosutinib isomer 4; PF-06651481; PF-06651481-00. Grades: > 95%. CAS No. 1391063-17-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.46.
Bosutinib Isomer Methanoate
Bosutinib Isomer is the 3,5-dichloro-4-methoxy isomer of Bosutinib. It has been reported that this compound has been offered incorrectly as Bosutinib (B676095) C&E News 90 (21) 2012 34-35 and Levinson NM, Boxer SG (2012) Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain. PLoS ONE 7(4): e29828. doi:10. 1371/journal. pone. 0029828. Group: Biochemicals. Alternative Names: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Methanoate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Bosutinib methanoate
Bosutinib methanoate. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile methanoate; SKI 606 methanoate. Grades: Highly Purified. CAS No. 918639-10-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C27H33Cl2N5O4. US Biological Life Sciences.
Worldwide
Bosutinib Monohydrate
Bosutinib Monohydrate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 918639-08-4. Molecular Formula: C26H31Cl2N5O4. Mole Weight: 548.47. Catalog: APB918639084.
Boswellia Serrata Extract. Group: Others. Purity: 10:1, 20:1, Boswellic acid40% 50% 65%. Appearance: Brown powder. Source: Boswellia is a genus of trees in the order Sapindales, known for their fragrant resin which has many pharmacological uses, particularly as anti-inflammatories. Boswellia Serrata Extract. Cat No: EXTC-175.
Botensilimab
Botensilimab (AGEN 1181), a human anti- cytotoxic T-lymphocyte antigen 4 (CTLA-4) monoclonal antibody, is an innate and adaptive immune activator. Botensilimab can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AGEN 1181. CAS No. 2408310-37-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99484.
bothrolysin
A 22.5 kDa endopeptidase from the venom of the jararaca snake (Bothrops jararaca), insensitive to phosphoramidon at 0.5 mM. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Bothrops metalloendopeptidase J; J protease. Enzyme Commission Number: EC 3.4.24.50. CAS No. 443890-65-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4332; bothrolysin; EC 3.4.24.50; 443890-65-1; Bothrops metalloendopeptidase J; J protease. Cat No: EXWM-4332.
bothropasin
Caseinolytic endopeptidase of jararaca snake (Bothrops jararaca) venom; 48 kDa. In peptidase family M12. Group: Enzymes. Synonyms: Bothrops jararaca venom metalloproteinase. Enzyme Commission Number: EC 3.4.24.49. CAS No. 84788-89-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4331; bothropasin; EC 3.4.24.49; 84788-89-6; Bothrops jararaca venom metalloproteinase. Cat No: EXWM-4331.
Botrydial
Botrydial is a phytotoxic sesquiterpene metabolite secreted by the fungus Botrytis cinerea. It has anti-candida fungi activity and has only weak antibacterial effect. CAS No. 54986-75-3. Molecular formula: C17H26O5. Mole weight: 310.38.
BOTRYOCOCCANE C30-C32
BOTRYOCOCCANE C30-C32. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BOTRYOCOCCANE C30-C32. Product Category: Heterocyclic Organic Compound. CAS No. 100664-65-1. Molecular formula: C93H192. Mole weight: 1310.52. Product ID: ACM100664651. Alfa Chemistry ISO 9001:2015 Certified.
botryococcene C-methyltransferase
Isolated from the green alga Botryococcus braunii BOT22. Shows a very weak activity with squalene. Group: Enzymes. Synonyms: TMT-3. Enzyme Commission Number: EC 2.1.1.263. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1868; botryococcene C-methyltransferase; EC 2.1.1.263; TMT-3. Cat No: EXWM-1868.
botryococcene synthase
Isolated from the green alga Botryococcus braunii BOT22. Acts in the reverse direction. Involved in the production of botryococcenes, which are triterpenoid hydrocarbons of isoprenoid origin produced in large amount by this alga. Group: Enzymes. Synonyms: SSL-3 (gene name). Enzyme Commission Number: EC 1.3.1.97. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1367; botryococcene synthase; EC 1.3.1.97; SSL-3 (gene name). Cat No: EXWM-1367.
Botryococcus squalene synthase
Isolated from the green alga Botryococcus braunii BOT22. Acts in the reverse direction. cf. EC 2.5.1.21, squalene synthase, where squalene is formed directly from farnesyl diphosphate. Group: Enzymes. Synonyms: SSL-2 (gene name). Enzyme Commission Number: EC 1.3.1.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1366; Botryococcus squalene synthase; EC 1.3.1.96; SSL-2 (gene name). Cat No: EXWM-1366.
Botryodiplodin
Botryodiplodin is an antibiotic mycotoxin produced by Botryodiplodia theobromae. It has activity against gram-positive bacteria. Synonyms: Cytostipin; Antibiotic PSX 1; Botryodipolodin. Grades: >98%. CAS No. 27098-03-9. Molecular formula: C7H12O3. Mole weight: 144.17.
Bottromycin
Bottromycin is a peptide antibiotic produced by Streptomyces bottropensis. It has anti-gram-positive bacteria, mycobacteria, gram-negative bacteria (individually) and mycoplasma activity. Synonyms: Bottromycin A2. CAS No. 15005-62-6. Molecular formula: C42H62N8O7S. Mole weight: 823.05.
Bottromycin B2
Bottromycin B2 is a peptide antibiotic produced by Streptomyces bottropensis. It has anti-gram-positive bacteria, mycobacteria, gram-negative bacteria (individually) and mycoplasma activity. Molecular formula: C41H60N8O7S. Mole weight: 809.03.
Bourgeonal
Bourgeonal (Cyclamen Propanal). CAS No. 18127-01-0. Kosher: Y. VIGON Item # 503204. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers, Aromatic Aldehyde used in perfumery, 3-(4-tert-butylphenyl)propanal
America & Internationally
Bourgeonal
Bourgeonal is a potent agonist of hOR17-4 and acts as a strong chemoattractant in sperm behavioral assays [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18127-01-0. Pack Sizes: 500 mg. Product ID: HY-31962.
Bourgeonal
A potent agonist at hOR17-4 (a human testicular olfactory receptor) and acts as a strong chemoattractant in sperm behavioral assays. The bourgeonal-hOR17-4 signaling pathway potentially governs chemical communication between sperm and egg and may be used to manipulate or block fertilization. Bourgeonal is an aromatic aldehyde used in perfumery. It has a fragrance reminiscent of lily of the valley, otherwise described as floral, watery, green and aldehydic. It is a pale yellow liquid at room temperature. Group: Biochemicals. Alternative Names: 4-tert-Butyl Benzene propionaldehyde; 4- (1, 1-Dimethylethyl) benzenepropanal; 3-(4-tert-Butylphenyl)propanal. Grades: Highly Purified. CAS No. 18127-01-0. Pack Sizes: 10mg. Molecular Formula: C??H??O, Molecular Weight: 190.28. US Biological Life Sciences.
Worldwide
Bourgeonal (4-tert-Butyl Benzene propionaldehyde)
A potent agonist at hOR17-4 (a human. Group: Biochemicals. Alternative Names: 4-tert-Butyl Benzene propionaldehyde. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Bovine Adrenal Freeze Dried Powder
Bovine Adrenal Freeze Dried Powder.
CA, FL & NJ
Bovine Adrenal Gland Substance Powder
Bovine Adrenal Gland Substance Powder.
CA, FL & NJ
Bovine Adrenal Substance Powder
Bovine Adrenal Substance Powder.
CA, FL & NJ
Bovine Beta-defensin 10
Bovine Beta-defensin 10 is an antibacterial peptide isolated from Bos taurus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Gln-Gly-Val-Arg-Ser-Tyr-Leu-Ser-Cys-Trp-Gly-Asn-Arg-Gly-Ile-Cys-Leu-Leu-Asn-Arg-Cys-Pro-Gly-Arg-Met-Arg-Gln-Ile-Gly-Thr-Cys-Leu-Ala-Pro-Arg-Val-Lys-Cys-Cys-Arg.
Bovine Beta-defensin 3
Bovine Beta-defensin 3 is an antibacterial peptide isolated from Bos taurus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Gln-Gly-Val-Arg-Asn-His-Val-Thr-Cys-Arg-Ile-Asn-Arg-Gly-Phe-Cys-Val-Pro-Ile-Arg-Cys-Pro-Gly-Arg-Thr-Arg-Gln-Ile-Gly-Thr-Cys-Phe-Gly-Pro-Arg-Ile-Lys-Cys-Cys-Arg-Ser-Trp.
Bovine Beta-defensin 5
Bovine Beta-defensin 5 is an antibacterial peptide isolated from Bos taurus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Gln-Val-Val-Arg-Asn-Pro-Gln-Ser-Cys-Arg-Trp-Asn-Met-Gly-Val-Cys-Ile-Pro-Ile-Ser-Cys-Pro-Gly-Asn-Met-Arg-Gln-Ile-Gly-Thr-Cys-Phe-Gly-Pro-Arg-Val-Pro-Cys-Cys-Arg-Arg-Trp.
Bovine Brain Freeze Dried Powder
Bovine Brain Freeze Dried Powder.
CA, FL & NJ
Bovine Catalase-polyethylene glycol
PEG labeled catalase is one of PEGylated catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is an important enzyme in protecting the cell from oxidative damage by reactive oxygen species. PEG modified catalase shows better stability with good reactivity. We provide a variety of chemically functionalized and bio-conjugated catalase with different functionality. These functionalized catalase conjugates were purified by size exclusion chromatography to ensure adequate applications both in-vitro and in-vivo. Group: Enzymes. Synonyms: PEG-Catalase; Catalase-polyethylene glycol; CAT-PEG. CAS No. 9001-5-2. CAT. Mole weight: ~250 KDa. Activity: 2000-5000 units/mg before conjugation; 20~50 PEG5000 on each catalase molecule. Storage: Store at -20°C. Form: Lyophilized powder. Source: Bovine liver. Species: Bovine. PEG-Catalase; Catalase-polyethylene glycol; CAT-PEG. Pack: Package size based on protein content. Cat No: NATE-0111.
Bovine collagen peptide
Bovine collagen peptide was prepared from bovine bone or skin by enzymatic hydrolysis. Use advanced technology to remove inorganic salt, fat and non-collagen protein, retain collagen essence, and can customize products according to customer needs. Product ID: CDF4-0244. Category: Protein peptide. Product Keywords: Protein Peptides; Bovine collagen peptide; CDF4-0244; Protein peptide;. Applications: It is widely used in food, cosmetics and medicine. Product Description: Bovine collagen peptide has small molecular weight, high purity, protein content ≥ 90%, good solubility, high thermal and acid stability.
Bovine Collagen Peptide
Bovine Collagen Peptide is a food additive and supplement.
Bovine Collagen powder
Bovine collagen is a naturally occurring protein that is found in the skin, bones, and muscles of cows. This collagen is so similar to human collagen that many people in the beauty industry have embraced its use as a cost-effective way to treat wrinkles and fine lines. Acting as a replacement to human collagen, it can be used to fill fine lines and correct scars. Group: Others. Synonyms: Collagen. Purity: > 90%. Collagen. Appearance: White powder. Source: Bovine. Collagen; Bovine Collagen powder; Bovine Collagen. Cat No: COL-0200.
Bovine Collagen Solution
Bovine Collagen Solution. Group: Natural polymers and biopolymers. CAS No. 9007-34-5.
Bovine Collagen Type 1
Bovine Collagen Type 1.
CA, FL & NJ
Bovine Colostrum 30% IgG Powder
Bovine Colostrum 30% IgG Powder.
CA, FL & NJ
Bovine Colostrum Powder
Colostrum is a milky fluid that comes from the breasts of humans, cows, and other mammals the first few days after giving birth, before true milk appears. It contains proteins, carbohydrates, fats, vitamins, minerals, and proteins (antibodies) that fight disease-causing agents such as bacteria and viruses. Antibody levels in colostrums can be 100 times higher than levels in regular cows milk. Group: Others. Synonyms: Bovine Colostrum; Bovine Immunoglobulin; Bovine Lacteal Compounds; Calostro; Colostrum Bovin; Colostrum Bovin Hyperimmune; Cow Milk Colostrum; Goat Colostrum; Hyperimmune Bovine Colostrum; Immunoglobuline Bovine; Lait Colostral; Protogala. Appearance: Yellow powder. Source: Bovine. Bovine Colostrum Powder. Cat No: BCP-0100.
BOVINE COLOSTRUM POWDER
BOVINE COLOSTRUM POWDER. Group: other nano materials. CAS No. 146897-68-9. 99.9%.
Bovine Defatted Liver Powder
Bovine Defatted Liver Powder.
CA, FL & NJ
Bovine factor IX
The zymogen factor IX is a single chain vitamin K-dependent glycoprotein which is synthesized in the liver. The domain structure of factor IX is similar to that of the other vitamin K dependent coagulation factors. The NH2-terminal region contains 12 γ-carboxyglutamic acid (gla) residues which facilitate the calcium dependent binding of factor IX to negatively charged phospholipid surfaces. Two domains which are homologous to epidermal growth factor (EGF) span the region between the NH2-terminal gla domain and the activation peptide (Ala-146 to Arg-180).Factor IX is activated by either factor XIa or the factor VIIa/tissue factor/phospholipid complex. Cleavage at site A (see fig... activates factor X to factor Xa.Human factor IX is prepared from fresh frozen plasma by a combination of conventional procedures and immunoaffinity chromatography. Bovine factor IX is prepared from fresh citrated bovine plasma by a modification of the method described by Fujikawa et al. The purified proteins are supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a factor IX clotting assay. Group: Zymogens. CAS No. 9001-28-9. Purity: >95% by SDS-PAGE. Factor IX. Mole weight: 55400. Stability: 12 months. Storage: -20°C. Source: Bovine. Bovine factor IX; Factor IX. Pack: 100 ug. Cat No: CZY-003.
Bovine Factor X
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a disulfide bond. Prior to secretion into plasma, post-translational modifications produce 11 gamma-carboxyglutamic acid (gla) residues and a single b-hydroxyaspartic acid residue, which are located within the NH2-terminal light chain. The light chain also contains two epidermal growth factor (EGF) homology domains. The COOH-terminal heavy chain of factor X contains most of the carbohydrate moieties, as well as the latent serine protease domain. The activation of factor X is catalyzed by either the intrinsic factor Xase complex (factor IXa, fa...y of the prothrombinase complex. The first EGF homology domain contains a Ca2+ binding site which acts as a hinge to fold the EGF and GLA domains towards each other. This region of the molecule is involved in the recognition of cellular binding domains.Human factor X is isolated from fresh frozen human plasma by a combination of conventional techniques and immunoaffinity chromatography. In addition to the standard human factor X preparation, Gla-domainless human factor X is also available. Bovine factor X is isolated from fresh bovine plasma using a modification of the procedure reported by Bajaj et al. The purified zymogen is supplied in 50% (vol/vol) glycerol/H2O and should be store
Bovine fibrillar collagen solution
Bovine fibrillar collagen solution. Group: Natural polymers and biopolymers. CAS No. 9007-34-5.
Bovine Freeze Dried Adrenal Substance Powder
Bovine Freeze Dried Adrenal Substance Powder.
CA, FL & NJ
Bovine Freeze Dried Bone Marrow Powder
Bovine Freeze Dried Bone Marrow Powder.
CA, FL & NJ
Bovine glu-Plasminogen
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4 uM. The plasminogen molecule contains 790 amino acids, 24 disulfide bridges, no free sulfhydryls and 5 regions of internal sequence homology, known as kringles, between Lys77 and Arg560. These five triple-looped, three disulfide bridged, kringle regions are homologous to the kringle domains in t-PA, u-PA and prothrombin. Plasminogen contains one high affinity (Kd=9x10-6M) and four low affinity (Kd=5x10-3M) lysine binding sites. The high affinity binding site resides within the first kringle region of plasminogen. The interaction of p...hich remain covalently associated by a disulfide bond.Native glu-plasminogen is prepared from fresh frozen human plasma by a modification of the procedure of Castellino, utilizing gel filtration and affinity chromatography. The two carbohydrate variants of glu-plasminogen (CHOI and CHOII) are isolated by gradient elution from lysine-Sepharose using the lysine analog, e-aminocaproic acid. The plasminogen is supplied in 50% (vol/vol) glycerol/H2O for storage at -20°C. Purity is determined by SDS-PAGE analysis. Group: Zymogens. Purity: >95% by SDS-PAGE. Plasminogen. Stability: 12 months. Storage: -20°C. Source: Bovine. Bovine glu-Plasminogen; Plasminogen. Pack: 1 mg. Cat No: CZY-015.
Bovine Heme Iron Polypeptide (HIP) 2% Iron
Bovine Heme Iron Polypeptide (HIP) 2% Iron.
CA, FL & NJ
Bovine Hemoglobin Powder
Bovine Hemoglobin Powder.
CA, FL & NJ
Bovine Liver Defatted Powder (40 Mesh)
Bovine Liver Defatted Powder (40 Mesh).
CA, FL & NJ
Bovine Lung Powder
Bovine Lung Powder.
CA, FL & NJ
Bovine Lymphatic Substance Powder
Bovine Lymphatic Substance Powder.
CA, FL & NJ
Bovine Lymph Freeze Dried Powder
Bovine Lymph Freeze Dried Powder.
CA, FL & NJ
Bovine Neutrophil beta-defensin 5
Neutrophil beta-defensin 5 is an antimicrobial peptide found in Bos taurus (Bovine), and has antibacterial activity. Synonyms: BNBD 5; Neutrophil beta-defensin 5. Grades: >98%.
Purified from freshly collected bovine plasma. The protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. No Plasmin activity is detected using chromogenic substrate S-2251. Plasminogen is activated to the serine protease plasmin via urokinase, streptokinase or tissue plasminogen activator. Group: Zymogens. Purity: >94% by SDS-PAGE. Plasminogen. Mole weight: 90,000-94,000. Stability: 30 months. Storage: 2-8°C. Source: Bovine. Bovine Plasminogen; Plasminogen. Pack: 1mg. Cat No: CZY-030.
Bovine Protein C
The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide linked heterodimer, by removal of a dipeptide (Lys-146 and Arg-147) from the precursor molecule. Trace quantities of the single chain form have been observed in plasma. The light chain, which is responsible for the calcium dependent binding of protein C to phospholipid vesicles, contains 11 γ-carboxyglutamic acid (gla) residues, 1 b-hydroxyaspartic acid residue, and 2 epidermal growth factor (EGF) homology domains. The serine protease catalytic triad is located in the heavy chain. Human protein C is susceptible to proteolytic cleavag...g the proteolytic inactivation of factors Va and VIIIa. APC also contributes to the fibrinolytic response by complex formation with plasminogen activator inhibitors.Bovine protein C is prepared from fresh citrated bovine plasma by a modification of the Walker procedure, as described by Haley et al. Human protein C is prepared from fresh frozen citrated human plasma using a combination of immunoaffinity chromatography, and conventional techniques. Protein C is provided in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a chromogenic substrate based assay. Group: Zymogens. Purity: >95% by SDS-PAGE. Prote
Bovine Prothrombin
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature p...Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20
Bovine Serum Albumin
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Albumin bovine serum; BSA. CAS No. 9048-46-8. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0842.