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| Product | Description | |
|---|---|---|
| Brefeldin a | Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NECTROLIDE;SYNERGISIDIN;4h-cyclopent(f)oxacyclotridecin-4-one,1,6,7,8,9,11a-beta,12,13,14,14a-alpha-de;cahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-;cyanaein;CYANEIN;DECUMBIN;GAMMA-4-DIHDYROXY-2-(6-HYDROXY-1-HEPTENYL)-4-CYCLOPENTANECROTONIC ACID LAMBDA-LACTONE. Product Category: Inhibitors. CAS No. 20350-15-6. Molecular formula: C16H24O4. Mole weight: 280.36. Purity: 0.9987. Product ID: ACM20350156. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Brefeldin A | Brefeldin A (BFA) is a fungal metabolite demonstrated to reversibly interfere with anterograde transport from the endoplasmic reticulumto the Golgi apparatus (1,2). While initially isolated as an antibiotic (3), and does have a wide range of antibiotic activity, it is primarily used as a biological research tool for studying protein transport. Treatment leads to a rapid accumulation of proteins within the ER and collapse of the Golgi stacks. Treatment with BFA can also inhibit protein secretion (4) and prolonged exposure can induce apoptosis (5). The main target of BFA appears to be ADP-ribosylation factor (ARF), which is responsible for association of coat protein to the Golgi membrane (6,7). Group: Biochemicals. Alternative Names: gamma-4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda -lactone; Ascotoxin; BFA; Cyanein; Decumbin;g-4-Dihdyroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid, ?-Lactone, BFA; Cyanein; Decumbin; Synergisidin; Nectrolide. Grades: Purified. CAS No. 20350-15-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H24O4, Molecular Weight: 280.36. US Biological Life Sciences. |  Worldwide |
| Brefeldin A | Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus [1] [2]. Brefeldin A is also an autophagy and mitophagy inhibitor [3]. Brefeldin A is a CRISPR/Cas9 activator [5]. Brefeldin A inhibits HSV-1 and has anti-cancer activity [5]. Uses: Scientific research. Group: Natural products. Alternative Names: BFA; Cyanein; Decumbin. CAS No. 20350-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16592. |  |
| Brefeldin A | 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H24O4. CAS No. 20350-15-6. Prepack ID 17689223-10mg. Molecular Weight 280.36. See USA prepack pricing. |  |
| Brefeldin B | Brefeldin is an antibiotic produced by Penicillum brefeldianum S-464, Pen. cyaneum S-ll, Pen. decumbens, Pen. simplicissimum S-544, etc. Molecular formula: C15H22O4. Mole weight: 266.33. |  |
| Brefeldin C | Brefeldin is an antibiotic produced by Penicillum brefeldianum S-464, Pen. cyaneum S-ll, Pen. decumbens, Pen. simplicissimum S-545, etc. Synonyms: (1S,2Z,7S,10Z,12R,13R)-12-hydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one; 4H-Cyclopent(f)oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1-hydroxy-6-methyl-, (1R-(1R*,2E,6S*,10E,11aS*,14aR*))-. Grades: 95%. CAS No. 73899-78-2. Molecular formula: C16H24O3. Mole weight: 264.36. | |
| Bremelanotide | Bremelanotide is a peptide melanocortin receptor agonist developed for the treatment of sexual dysfunction, hemorrhagic shock and reperfusion injury. Synonyms: (Ac-Nle4, Asp5, D-Phe7, Lys10)-cyclo-α-MSH (4-10); PT 141; PT-141; PT141. CAS No. 189691-06-3. Molecular formula: C50H68N14O10. Mole weight: 1025.16. | |
| Bremelanotide | Bremelanotide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bremelanotide;Bremelanotide PT 141;Bremelanotide;Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH;PT-141. Product Category: Heterocyclic Organic Compound. CAS No. 189691-06-3. Molecular formula: C50H68N14O10. Mole weight: 1025.16. Density: 1.43. Product ID: ACM189691063. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bremelanotide Acetate | Bremelanotide Acetate (PT-141 Acetate), a synthetic peptide analogue of α-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R for the treatment of sexual dysfunction [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PT-141 Acetate. CAS No. 1607799-13-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18678A. | |
| Bremelanotide Acetate | Bremelanotide Acetate is a heptapeptide melanocortin agonist. Bremelanotide, formerly known as PT-141, employed in clinical trials for sexual dysfunction including both male erectile dysfunction (ED) and female sexual dysfunction or disorder (FSD), is a f. Synonyms: PT141 acetate. CAS No. 1607799-13-2. Molecular formula: C52H72N14O12. Mole weight: 1085.22. | |
| Bremelanotide Acetate Hydrate | Bremelanotide is a melanocortin receptor agonist shown to improve female sexual function in females suffering from sexual dysfunction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C52H74N14O13. US Biological Life Sciences. | Worldwide |
| Brensocatib | Brensocatib (AZD7986) is an oral dipeptidyl peptidase 1 ( DPP1 ) inhibitor with pIC 50 s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD7986; INS 1007. CAS No. 1802148-05-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101056. | |
| Brentuximab | Brentuximab is a chimeric antibody directed against CD30, a protein often found at high levels on classical Hodgkin lymphoma cells (called Reed-Sternberg cells). CAS No. 2088770-90-3. | |
| Brentuximab | Brentuximab is a monoclonal antibody targeting CD30. Brentuximab is conjugated with monomethyl auristatin E (MMAE) (HY-15162) to form the antibody-drug conjugate Brentuximab vedotin (HY-P99107), which can induce apoptosis in primary effusion lymphoma cells. Brentuximab vedotin exhibits antitumor activity with an IC 50 of 10 nM against human CD30+ cancer cells [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2088770-90-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99151. | |
| Brentuximab vedotin (solution) | Brentuximab vedotin (solution) is the solution form of Brentuximab vedotin (cAC10-vcMMAE) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 914088-09-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99107A. | |
| Brepocitinib | Brepocitinib (PF-06700841) is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC 50 s of 17 nM and 23 nM, respectively. Brepocitinib also inhibits JAK2 and JAK3 with IC 50 s of 77 nM and 6.49 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06700841. CAS No. 1883299-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112708. | |
| Brequinar | Brequinar is a synthetic quinolinecarboxylic acid analogue with antineoplastic properties. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby blocking de novo pyrimidine biosynthesis. This agent may also enhance the in vivo antitumor effect of antineoplastic agents such as 5-FU. Check for active clinical trials or closed clinical trials using this agent. Synonyms: DUP785; NSC 368390; 6-Fluoro-2-(2'-fluoro-[1,1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid; 6-fluoro-2-(2'-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-; Biphenquinate. Grades: ≥98%. CAS No. 96187-53-0. Molecular formula: C23H15F2NO2. Mole weight: 375.37. | |
| Brequinar sodium | Brequinar sodium is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = ~20 nM), which causes the blockade of de novo pyrimidine nucleotide biosynthesis. Uses: Antineoplastic agents. Synonyms: Dup785; Dup 785; Dup-785; Brequinar Sodium. 6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium; Dup 785. Grades: ≥99% by HPLC. CAS No. 96201-88-6. Molecular formula: C23H14F2NO2Na. Mole weight: 397.35. | |
| Bretazenil | Bretazenil (Ro 16-6028) is a partial agonist at the gamma-aminobutyric acid A (GABA A ) receptor-linked benzodiazepine site. Bretazenil is potent benzodiazepine examined, exhibiting an IC 50 (concentration at which half-maximal inhibition of specific [35S]TBPS binding occurs) of 6.1 nM. Bretazenil shows an EC 50 of 10 nM for recombinant α1β1γ2. Anticonvulsant effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 16-6028. CAS No. 84379-13-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105056. | |
| Bretazenil | Bretazenil. Group: Biochemicals. Grades: Purified. CAS No. 84379-13-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bretazenil | Bretazenil, also known as Ro 16-6028, is GABA A receptor agonist potentially for the treatment of anxiety disorders. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5 and α6 subunit containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ro 16-6028; Ro 16 6028; Ro16-6028; Ro 166028; Ro 166028; Ro166028; Ro 16-6028/000; Bretazenil. Product Category: Agonists. Appearance: Solid powder. CAS No. 84379-13-5. Molecular formula: C19H20BrN3O3. Mole weight: 418.29. Purity: >97%. IUPACName: tert-butyl (S)-8-bromo-9-oxo-11,12,13,13a-tetrahydro-9H-benzo[e]imidazo[5,1-c]pyrrolo[1,2-a][1,4]diazepine-1-carboxylate. Canonical SMILES: O=C(C1=C([C@@]2([H])N3CCC2)N(C=N1)C4=CC=CC(Br)=C4C3=O)OC(C)(C)C. Density: 1.56 g/cm³. Product ID: ACM84379135. Alfa Chemistry ISO 9001:2015 Certified. | |
| BrettPhos | BrettPhos. Uses: Ligand for palladium-catalyzed cross-coupling reactions using aryl mesylates with electron-deficient anilines. ligand for palladium-catalyzed cross-coupling of primary arylamines at low catalyst loading. ligand for palladium-catalyzed cross-coupling of aryl iodides and primary amines. ligand for the suziki-miyaura coupling of tosylates and mesylates. ligand for the palladium-catalyzed trifluor. Additional or Alternative Names: C35H53O2P; dicyclohexyl-(2',4',6'-triisopropyl-3,6-dimethoxy-biphenyl-2-yl)-phosphane; BrettPhos; 2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl; ZINC43220891; ST24046493; 2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISOPROPYL-3,6-DIMETHOXYBIPHENYL; AS-19342; 2-(Dicyclohexylphosphino)3,6-dimethoxy-2 inverted exclamation marka,4 inverted exclamation marka,6 inverted exclamation. Product Category: Organic Phosphine Compounds. CAS No. 1070663-78-3. Molecular formula: C35H53O2P. Mole weight: 536.781g/mol. IUPACName: dicyclohexyl-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane. Canonical SMILES: CC(C)C1=CC(=C(C(=C1)C(C)C)C2=C(C=CC(=C2P(C3CCCCC3)C4CCCCC4)OC)OC)C(C)C. Product ID: ACM1070663783. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bretylium tosylate | Bretylium (tosylate) is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters. Uses: Scientific research. Group: Signaling pathways. CAS No. 61-75-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12961A. | |
| Bretylium Tosylate | Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competitive inhibitor of acetylcholinesterase. Group: Biochemicals. Alternative Names: 2-Bromo-N-ethyl-N, N-dimethyl Benzene methanaminium 4-Methyl Benzene sulfonate; (o-Bromobenzyl) ethyldimethylammonium p-Toluenesulfonate; (o-Bromobenzyl) ethyldimethylammonium p-Toluenesulfonate; ASL 603; Bretylan; Bretylate; Bretylium p-Toluenesulfonate; Bretylium Tosilate; Bretylol; Darenthin; N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium Tosylate; NSC 62164; Ornid. Grades: Highly Purified. CAS No. 61-75-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bretylium Tosylate | Bretylium Tosylate, a class III antiarrhythmic agent, is an inhibitor of the presynaptic release of vasoconstrictive neurotransmitters and a blocker of sympathetic and adrenergic nerves. Synonyms: 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-Methylbenzenesulfonate; (o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate; (o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate; ASL 603; Bretylan; Bretylate; Bretylium p-Toluenesulfonate; Bretylium Tosilate; Bretylol; Darenthin; N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium Tosylate; NSC 62164; Ornid. Grades: ≥95%. CAS No. 61-75-6. Molecular formula: C18H24BrNO3S. Mole weight: 414.36. | |
| Bretylium Tosylate USP | (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate. Grades: USP. CAS No. 61-75-6. Product ID: 8-04419. Molecular formula: C18H24BrNO3S. Mole weight: 414.36. |  |
| Brevetoxin-3 | Brevetoxin-3 (PbTx-3) is a potent allosteric voltage-gated Na + channel activator and has multiple active centers (A-ring lactone, C-42 of R side chain) [1]. Brevetoxin-3 (PbTx-3) has a high affinity to site 5 of the voltage-sensitive Na + channels, inhibits the inactivation of Na + channels and prolongs the mean open time of these channels. Brevetoxin-3 (PbTx-3) repeated exposures can lead to prolonged airway hyperresponsiveness (AHR) and lung inflammation [2]. Uses: Scientific research. Group: Natural products. Alternative Names: PbTx-3. CAS No. 85079-48-7. Pack Sizes: 100 μg. Product ID: HY-12545. | |
| Brevetoxin 6 | Brevetoxin 6 is a polyacyl toxoid produced by Ptychodiscus brevis (Gymnodiniuin bervis). Synonyms: Brevetoxin PbTx-6. Molecular formula: C50H70O15. Mole weight: 911.08. | |
| Brevetoxin A | Brevetoxin A is a polyacyl toxoid produced by Ptychodiscus brevis (Gymnodiniuin bervis). It has a strong effect of activating cell membrane sodium channels, and Tetrodotoxin can counteract its activity. Uses: Adcs cytotoxin. Synonyms: Brevetoxin PbTx 1; Ptychodiscus brevis toxin 1. Grades: 98%. CAS No. 98112-41-5. Molecular formula: C49H70O13. Mole weight: 867.06. | |
| Brevetoxin B | Brevetoxin B is a polyacyl toxoid produced by Ptychodiscus brevis (Gymnodiniuin bervis). It has a strong effect of activating cell membrane sodium channels, and Tetrodotoxin can counteract its activity. Synonyms: PbTx-2. Grades: ≥95%. CAS No. 79580-28-2. Molecular formula: C50H70O14. Mole weight: 895.08. | |
| brevianamide F prenyltransferase (deoxybrevianamide E-forming) | The enzyme from the fungus Aspergilus sp. MF297-2 is specific for brevianamide F, while the enzyme from Aspergillus versicolor accepts a broad range of trytophan-containing cyclic dipeptides. Involved in the biosynthetic pathways of several indole alkaloids such as paraherquamides and malbrancheamides. Group: Enzymes. Synonyms: NotF; BrePT; brevianamide F reverse prenyltransferase. Enzyme Commission Number: EC 2.5.1.109. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2725; brevianamide F prenyltransferase (deoxybrevianamide E-forming); EC 2.5.1.109; NotF; BrePT; brevianamide F reverse prenyltransferase. Cat No: EXWM-2725. |  |
| Brevianamide L | Brevianamide L is an alkaloid metabolite produced by various Streptomyces, Actinomycetes, and Aspergillus strains. CAS No. 1174538-68-1. Molecular formula: C22H23N3O4. Mole weight: 393.44. | |
| Brevicompanine B | A diketopiperazine-related metabolite produced by penicillium brevicompactum and aspergillus species. It has obvious plant growth regulation activity, but is devoid of antifungal or antimicrobial activity. It is active against Plasmodium falciparum. Synonyms: (3R,5aS,10bR,11aS)-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grades: >99% by HPLC. CAS No. 215121-47-4. Molecular formula: C22H29N3O2. Mole weight: 367.48. | |
| Brevicompanine B | Brevicompanine B is a diketopiperazine related metabolite produced by Penicillium and Aspergillus species. Brevicompanine B was found to be active against the malaria parasite Plasmodium falciparum and has been demonstrated to show pronounced plant growth regulatory activity but is devoid of antifungal or antibacterial activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 215121-47-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Brevifolincarboxylic acid | Brevifolincarboxylic acid. Group: Biochemicals. Grades: Plant Grade. CAS No. 18490-95-4. Pack Sizes: 10mg. Molecular Formula: C13H8O8, Molecular Weight: 292.2. US Biological Life Sciences. | Worldwide |
| Brevifolincarboxylic acid | Brevifolincarboxylic acid is extracted from Polygonum capitatum [1] , has inhibitory effect on the aryl hydrocarbon receptor ( AhR ) [2]. Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC 50 of 323.46 μM [3]. Uses: Scientific research. Group: Natural products. CAS No. 18490-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4095. | |
| Brevinin-1 | The unique antimicrobial peptide named brevinin-1 was isolated from the skin of the frog, Rana brevipoda porsa. The minimum inhibitory concentration of brevinin-1 against the growth of St. aureus and E. coli was determined to be 8 micrograms/ml and 34 micrograms/ml. Synonyms: Brevinin-1; 145963-49-1; brevinin-1 protein, Rana; Brevinin 1; AMGDYQVEJJSZSQ-IMDMOUBVSA-N; Brevinin-1 (KFHEKHHSHRGY-acid); C121H202N28O26S2; RS-2012; C121-H202-N28-O26-S2. CAS No. 145963-49-1. Molecular formula: C121H202N28O26S2. Mole weight: 2529.2. | |
| Brevinin-1-01 | Brevinin-1-01 was found in Amolops sp. jingdongensis. It has antimicrobial activity. | |
| Brevioxime | Brevioxime is a heterocyclic antibiotic produced by Penicillum bervicompactum. Molecular formula: C15H22N2O3. Mole weight: 278.35. | |
| Breviscapine | Breviscapine is a crude flavonoid extract of Breviscapine, which is more than 85% of the active ingredient, Breviscapine. Breviscapine has a wide range of cardiovascular pharmacological activities, such as increasing blood flow, improving microcirculation, dilating blood vessels, reducing blood viscosity, promoting fibrinolysis, inhibiting platelet aggregation and thrombosis. Breviscapine has been used in the study of cerebral infarction and its sequelae, cerebral thrombosis, coronary heart disease and angina pectoris [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Breviscapinun. CAS No. 116122-36-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-107802. | |
| Breviscapine Liposome | Breviscapine is a mixture of apigenin-7-O-β-D-glucuronide and scutellarin, which is widely used in cardiovascular and cerebrovascular diseases as it dilates cerebral blood vessels and resists platelet aggregation. This product is a PEGylated pre-formulated liposome with breviscapine. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Brexpiprazole | Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D 2L receptor with K i s of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a K i of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α 1B (K i =0.17 nM) and α 2C receptors (K i =0.59 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-34712. CAS No. 913611-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15780. | |
| Brexpiprazole | Brexpiprazole is a novel atypical antipsychotic drug. It is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). It is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders. Uses: Brexpiprazole is approved for the treatment of schizophrenia, and as an adjunctive treatment for depression. it is a drug candidate useful in treatment and prevention of mental disorders including cns disorders. Synonyms: 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one; OPC 34712. Grades: > 95%. CAS No. 913611-97-9. Molecular formula: C25H27N3O2S. Mole weight: 433.58. | |
| Brexpiprazole-d8-1 | Brexpiprazole-d 8 -1 (OPC-34712-d 8 -1) is the deuterium labeled Brexpiprazole (HY-15780) [1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D 2L receptor with K i s of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a K i of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B ( K i =0.17 nM) and α2C receptors ( K i =0.59 nM) [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: OPC-34712-d8-1. CAS No. 1427049-19-1. Pack Sizes: 500 μg; 1 mg. Product ID: HY-15780S1. | |
| Brexpiprazole dihydrochloride | The hydrochloride salt form of Brexpiprazole, whihch is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). Brexpiprazole exhibits high affinity for h5-HT1A (partial agonist), h5-HT2A (antagonist), hD2L (partial agonist), hα1B (antagonist) and hα2C-adrenergic (antagonist) receptors (Ki values <1 nM). Synonyms: OPC 34712 dihydrochloride; 7-(4-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one dihydrochloride. Grades: 98%. CAS No. 2512192-75-3. Molecular formula: C25H27N3O2S.2HCl. Mole weight: 506.49. | |
| Brexpiprazole Dimer Impurity 1 | Brexpiprazole Dimer Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,4-bis(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)butane. CAS No. 2250242-22-7. Molecular Formula: C28H34N4S2. Mole Weight: 490.73. Catalog: APB2250242227. |  |
| Brexpiprazole Impurity1 | Brexpiprazole Impurity1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-(4-chlorobutoxy)-1-(4-chlorobutyl)quinolin-2(1H)-one. Molecular Formula: C17H21Cl2NO2. Mole Weight: 342.26. Catalog: APB03316. | |
| Brexpiprazole Impurity 10 | Brexpiprazole Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-bromo-4-chlorobutane. CAS No. 6940-78-9. Molecular Formula: C4H8BrCl. Mole Weight: 171.46. Catalog: APB6940789. | |
| Brexpiprazole Impurity 10 | Brexpiprazole Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 15116-41-3. Molecular Formula: C16H15NO2. Mole Weight: 253.3. Catalog: APB15116413. | |
| Brexpiprazole Impurity 10 | Brexpiprazole Impurity 10 is an impurity of Brexpiprazole, a drug used to counter psychiatric afflictions such as schizophrenia and major depressive disorder. Synonyms: m-Cinnamanisidide; N-(3-Methoxyphenyl)-3-phenylpropenamide. Grades: > 95%. CAS No. 15116-41-3. Molecular formula: C16H15NO2. Mole weight: 253.30. | |
| Brexpiprazole Impurity 101 | Brexpiprazole Impurity 101. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 7,7'-(((quinoline-2,7-diylbis(oxy))bis(butane-4,1-diyl))bis(oxy))bis(quinolin-2(1H)-one). Molecular Formula: C35H33N3O6. Mole Weight: 591.65. Catalog: APB03426. | |
| Brexpiprazole Impurity 11 | Brexpiprazole Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-chloropropanoic acid. Molecular Formula: C3H5ClO2. Mole Weight: 108.52. Catalog: APB03460. | |
| Brexpiprazole Impurity 12 | Brexpiprazole Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-chloro-N-(3-methoxyphenyl)propanamide. CAS No. 21261-76-7. Molecular Formula: C10H12ClNO2. Mole Weight: 213.66. Catalog: APB21261767. | |
| Brexpiprazole Impurity 13 | Brexpiprazole Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H27N3O2S. Mole Weight: 433.57. Catalog: APB06891. | |
| Brexpiprazole Impurity 13 | Brexpiprazole Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 7-methoxy-3,4-dihydroquinolin-2(1H)-one. CAS No. 22246-17-9. Molecular Formula: C10H11NO2. Mole Weight: 177.2. Catalog: APB22246179. | |
| Brexpiprazole Impurity 14 | Brexpiprazole Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-hydroxy-3,4-dihydroquinolin-2(1H)-one. CAS No. 30389-33-4. Molecular Formula: C9H9NO2. Mole Weight: 163.17. Catalog: APB30389334. | |
| Brexpiprazole Impurity 15 | Brexpiprazole Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 8-hydroxy-3,4-dihydroquinolin-2(1H)-one. CAS No. 52749-50-5. Molecular Formula: C9H9NO2. Mole Weight: 163.17. Catalog: APB52749505. | |
| Brexpiprazole Impurity 16 | Brexpiprazole Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-hydroxy-3,4-dihydroquinolin-2(1H)-one. CAS No. 54197-66-9. Molecular Formula: C9H9NO2. Mole Weight: 163.17. Catalog: APB54197669. | |
| Brexpiprazole Impurity 18 | Brexpiprazole Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,4-bis(benzo[b]thiophen-4-yl)piperazine. CAS No. 1420987-86-5. Molecular Formula: C20H18N2S2. Mole Weight: 350.50. Catalog: APB1420987865. | |
| Brexpiprazole Impurity 19 | Brexpiprazole Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2,3-dihydro-[2,4'-bibenzo[b]thiophen]-4-yl)piperazine. CAS No. 1420987-85-4. Molecular Formula: C20H20N2S2. Mole Weight: 352.52. Catalog: APB1420987854. | |
| Brexpiprazole Impurity 19 | Brexpiprazole Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 616227-75-9. Molecular Formula: C15H13NO2. Mole Weight: 239.27. Catalog: APB616227759. | |
| Brexpiprazole Impurity2 | Brexpiprazole Impurity2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 7-(4-chlorobutoxy)-1-(4-chlorobutyl)quinolin-2(1H)-one. CAS No. 2059954-32-2. Molecular Formula: C17H21Cl2NO2. Mole Weight: 342.26. Catalog: APB2059954322. | |
| Brexpiprazole Impurity 20 | Brexpiprazole Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(benzofuran-4-yl)piperazine. CAS No. 105685-34-5. Molecular Formula: C12H14N2O. Mole Weight: 202.25. Catalog: APB105685345. | |
| Brexpiprazole Impurity 21 | Brexpiprazole Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-amino-3-chloropropan-1-ol hydrochloride. CAS No. 54798-73-1. Molecular Formula: C3H9Cl2NO. Mole Weight: 146.02. Catalog: APB54798731. | |
| Brexpiprazole Impurity 22 | Brexpiprazole Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C20H20N2S2. Mole Weight: 352.51. Catalog: APB06892. | |
| Brexpiprazole Impurity 26 | Brexpiprazole Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 79145-59-8. Molecular Formula: C12H12ClNO2. Mole Weight: 237.68. Catalog: APB79145598. | |
| Brexpiprazole Impurity 3 | Brexpiprazole Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-chlorobutyl)-7-hydroxyquinolin-2(1H)-one. CAS No. 2707945-50-2. Molecular Formula: C13H14ClNO2. Mole Weight: 251.71. Catalog: APB2707945502. | |
| Brexpiprazole Impurity 32 | Brexpiprazole Impurity 32. Uses: For analytical and research use. Group: Impurity standards. CAS No. 846038-18-4. Molecular Formula: C12H14N2S. Mole Weight: 218.32. Catalog: APB846038184. | |
| Brexpiprazole Impurity 33 | Brexpiprazole Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H27N3O4S. Mole Weight: 465.57. Catalog: APB06893. | |
| Brexpiprazole Impurity 35 | Brexpiprazole Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C29H35N3O3S. Mole Weight: 505.68. Catalog: APB06894. | |
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