A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Bucladesine calcium salt is a membrane permeable selective activator of PKA. It is absorbed very rapidly and almost completely when the aqueous solution is applied to the site where the skin has been excised. Besides, it is capable of significantly reducing the inflammatory oedema in the arachidonic acid induced ear oedema model in mice. Synonyms: Dibutyryl-cAMP calcium salt; DC2797 calcium salt; DC 2797 calcium salt; DC-2797 calcium salt. Grades: >98%. CAS No. 938448-87-4. Molecular formula: C18H24N5O8P·1/2Ca. Mole weight: 468.38.
Bucladesine Impurity 2
6-MB-cAMP is a selective stimulator of protein kinase A (cAMP agonist), which is commonly used as an Epac-negative control. Synonyms: N6- Monobutyryladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 70253-67-7. Molecular formula: C14H17N5O7P · Na. Mole weight: 421.3.
Bucladesine Impurity 5
Bucladesine Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1053-73-2. Molecular formula: C10H15N5O10P2. Mole weight: 427.2. Catalog: APB1053732.
Bucladesine sodium
Bucladesine sodium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16980-89-5. Molecular formula: C18H23N5NaO8P. Mole weight: 491.37. Catalog: APB16980895.
DB-cAMP is a membrane-permeant activator of protein kinase A, the cAMP agonist. Synonyms: N6, 2'- O- Dibutyryladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 16980-89-5. Molecular formula: C18H23N5O8P · Na. Mole weight: 491.4.
Buclizine dihydrochloride is an orally active antihistamine antiallergic compound. Buclizine dihydrochloride is a potent teratogen in the rat and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 129-74-8. Pack Sizes: 100 mg. Product ID: HY-A0128A.
Used as an antiemetic. Group: Biochemicals. Alternative Names: UCB-4445, Buclina, Longifene, Posdel, Vibazine. Grades: Highly Purified. CAS No. 129-74-8. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Buclizine hydrochloride
Buclizine hydrochloride is an antihistamine and anticholinergic of the piperazine derivative family. Synonyms: Buclizine dihydrochloride; 1- (4- (tert-Butyl)benzyl)-4- ( (4-chlorophenyl) (phenyl)methyl)piperazine dihydrochloride. Grades: > 98%. CAS No. 129-74-8. Molecular formula: C28H35Cl3N2. Mole weight: 505.952.
Bucumolol hydrochloride
Bucumolol hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bucumolol hydrochloride;Bucumalol;(+-)-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride;8-(2-Hydroxy-3-tert-butylaminopropoxy)-5-methylcoumarin hydrochloride;Bucumarol;CS 359;DL-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin. Product Category: Heterocyclic Organic Compound. CAS No. 36556-75-9. Molecular formula: C17H23NO4?ClH. Mole weight: 341.833. Product ID: ACM36556759. Alfa Chemistry ISO 9001:2015 Certified.
Buddlejasaponin IVb
Buddlejasaponin IVb. Group: Biochemicals. Grades: Plant Grade. CAS No. 152580-79-5. Pack Sizes: 20mg. Molecular Formula: C48H78O18, Molecular Weight: 943.13. US Biological Life Sciences.
Worldwide
Budesonide
Budesonide. Group: Biochemicals. Alternative Names: (11b,16a)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione. Grades: Highly Purified. CAS No. 51333-22-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C25H34O6. US Biological Life Sciences.
Worldwide
Budesonide
Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51333-22-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-13580.
Budesonide
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C25H34O6. CAS No. 51333-22-3. Prepack ID 37869156-1g. Molecular Weight 430.53. See USA prepack pricing.
Budesonide
250mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C25H34O6. CAS No. 51333-22-3. Prepack ID 37869156-250mg. Molecular Weight 430.53. See USA prepack pricing.
Budesonide 21-Sulfate
Budesonide 21-Sulfate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C25H34O9S, Molecular Weight: 510.6. US Biological Life Sciences.
Worldwide
Budesonide-d6
Labeled Budesonide, a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent. Group: Biochemicals. Alternative Names: (11 β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione-d6. Grades: Highly Purified. CAS No. 1134189-63-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Budesonide-d8
Labelled Budesonide, a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Budesonide EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,9S,10R,11S,13S,14S,16R,17S)-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one. CAS No. 13951-70-7. Molecular formula: C21H28O6. Mole weight: 376.44. Catalog: APB13951707.
Budesonide EP Impurity B
Budesonide EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one. CAS No. 1040085-98-0. Molecular formula: C23H30O6. Mole weight: 402.48. Catalog: APB1040085980.
Budesonide EP Impurity C
Budesonide EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4aR,4bS,5S,6aS,7aR,10aR,11aS,11bS)-5-hydroxy-7a-(hydroxymethyl)-4a,6a-dimethyl-9-propyl-4b,5,6,6a,10a,11,11a,11b,12,13-decahydrochryseno[2,3-d][1,3]dioxole-2,7(4aH,7aH)-dione. CAS No. 1040085-99-1. Molecular formula: C25H34O6. Mole weight: 430.53. Catalog: APB1040085991.
Budesonide impurity 24
Budesonide impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 131918-67-7. Molecular formula: C24H30O6. Mole weight: 414.5. Catalog: APB131918677.
Budesonide Impurity 24
Budesonide Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-oxo-2-((8R,9S,10R,11S,13S,16R,17S)-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)ethyl acetate. CAS No. 131918-72-4. Molecular formula: C24H32O6. Mole weight: 416.51. Catalog: APB131918724.
Budesonide Impurity 25
Budesonide Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8R,9S,10R,11S,13S,16R,17S)-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one. CAS No. 131918-73-5. Molecular formula: C21H26O6. Mole weight: 374.43. Catalog: APB131918735.
A non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent. Group: Biochemicals. Alternative Names: S-1320, Bidien, Cortivent, Entocort CR, Preferid, Pulmicort, rhinocort, Spirocort. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Budesonide (Standard)
Budesonide (Standard) is the analytical standard of Budesonide. This product is intended for research and analytical applications. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51333-22-3. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-13580R.
Budigalimab
Budigalimab (ABBV 181; PR 1648817) is a humanized, recombinant IgG1 monoclonal antibody targeting programmed cell death 1 ( PD-1 ) receptor. Budigalimab has an Fc mutation that reduces the inhibition of Fc receptor interactions and effector factors. Budigalimab can block the binding of PD-1 and PD-L1, which has anti-tumor activity. Budigalimab can be used in the study of solid tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV 181; PR 1648817. CAS No. 2098225-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99489.
Budiodarone tartrate
Budiodarone (ATI-2042) tartrate is a chemical analogue of Amiodarone (HY-14187) with balanced, multiple cardiac ion channel ( potassium , sodium and calcium channels ) inhibiting activity. Budiodarone tartrate is an antiarrhythmic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATI-2042 tartrate. CAS No. 478941-93-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14834A.
Budotitane
Budotitane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Budotitane, Budotitano, Budotitanum, Budotitane [INN], Budotitanum [Latin], Budotitano [Spanish], UNII-DV05VZD83V, CCRIS 2873, CID5486530, Diethoxy-(1-phenyl-1,3-butanedionato)titanium (IV), Diethoxybis(1-phenyl-1,3-butanedionato-O,O)titanium, Titanium, diethoxybis(1-phenyl-1,3-butanedionato)- (7CI), Titanium, diethoxybis(1-phenyl-1,3-butanedionato-kappaO,kappaO)-, Titanium, diethoxybis(1-phenyl-1,3-butanedionato-O,O)-, (17alpha,20E)-, 85969-07-9. Product Category: Heterocyclic Organic Compound. CAS No. 85969-07-9. Molecular formula: C24H28O6Ti. Mole weight: 460.346. Purity: 0.96. IUPACName: ethanolate; (Z)-3-oxo-1-phenylbut-1-en-1-olate; titanium(4+). Canonical SMILES: CCO.CCO.CC(=O)C=C(C1=CC=CC=C1)O.CC(=O)C=C(C1=CC=CC=C1)O.[Ti]. Product ID: ACM85969079. Alfa Chemistry ISO 9001:2015 Certified.
Buellolide
It is produced by the strain of Buellia canescens. Synonyms: 4-Chloro-7-(3,5-dichloro-2,4-dimethoxy-6-methylphenoxy)-5-methoxyisobenzofuran-1(3H)-one; NSC 357680; 1(3H)-Isobenzofuranone, 4-chloro-7-(3,5-dichloro-2,4-dimethoxy-6-methylphenoxy)-5-methoxy-. CAS No. 69799-33-3. Molecular formula: C18H15Cl3O6. Mole weight: 433.67.
Bufalin
Bufalin is a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro. Synonyms: 22-dienolide,3,14-dihydroxy-,(3-beta,5-beta)-bufa-2; 22-dienolide,3-beta,14-dihydroxy-5-beta-bufa-2; BUFA-20,22-DIENOLIDE, 3,14-DIHYDROXY-, (3B,5B)-; BUFALIN; (3BETA,5BETA)-3,14-DIHYDROXYBUFA-20,22-DIENOLIDE; 3-BETA-14-DIHYDROXY-5-BETA-BUFA-20,22-DIENOLIDE; 3BETA,14-DIHYDROXY-5BETA,20[22]-BUFADIENOLIDE; 5BETA,20[22]-BUFADIENOLIDE-3BETA,14-DIOL. Grades: >98%. CAS No. 465-21-4. Molecular formula: C24H34O4. Mole weight: 386.52.
Bufalin
Bufalin. Group: Biochemicals. Alternative Names: (3b,5b)-3,14-Dihydroxy-bufa-20,22-dienolide; 3b,14-dihydroxy-5b-bufa-20,22-dienolide. Grades: Highly Purified. CAS No. 465-21-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H34O4. US Biological Life Sciences.
Worldwide
Bufalin
Bufalin is an active component isolated from Chan Su, acts as a potent Na + /K + -ATPase inhibitor, binds to the subunit α1, α2 and α3, with K d of 42.5, 45 and 40 nM, respectively [1] [2]. Anti-cancer activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 465-21-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0877.
Bufalin
Bufalin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 22-dienolide,3,14-dihydroxy-,(3-beta,5-beta)-bufa-2;22-dienolide,3-beta,14-dihydroxy-5-beta-bufa-2;BUFA-20,22-DIENOLIDE, 3,14-DIHYDROXY-, (3B,5B)-;BUFALIN;(3BETA,5BETA)-3,14-DIHYDROXYBUFA-20,22-DIENOLIDE;3-BETA-14-DIHYDROXY-5-BETA-BUFA-20,22-DIENOLIDE;3BETA,14-DIHYDROXY-5BETA,20[22]-BUFADIENOLIDE;5BETA,20[22]-BUFADIENOLIDE-3BETA,14-DIOL. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 465-21-4. Molecular formula: C24H34O4. Mole weight: 386.52. Purity: 0.98. IUPACName: 5-[(3S,5R,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one. Canonical SMILES: CC12CCC(CC1CCC3C2CCC4(C3(CCC4C5=COC(=O)C=C5)O)C)O. Product ID: ACM465214. Alfa Chemistry ISO 9001:2015 Certified.
Bufarenogin
Pseudobufarenogin is a natural compound extracted from toad species with unknown details. Synonyms: ψ-Bufarenogin. Grades: >98%. CAS No. 17008-69-4. Molecular formula: C24H32O6. Mole weight: 416.51.
Bufeniode
Bufeniode. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bufeniodum [INN-Latin]; EINECS 244-781-8; Bufeniodo [INN-Spanish]; Proclival; Bufeniod; Bufeniode; bupheniode; Diiodobuphenine; Diastal. Product Category: Heterocyclic Organic Compound. CAS No. 22103-14-6. Molecular formula: C19H23I2NO2. Mole weight: 551.200360 [g/mol]. Purity: 0.96. IUPACName: 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]-2,6-diiodophenol. Canonical SMILES: CC(CCC1=CC=CC=C1)NC(C)C(C2=CC(=C(C(=C2)I)O)I)O. Density: 1.744g/cm³. ECNumber: 244-781-8. Product ID: ACM22103146. Alfa Chemistry ISO 9001:2015 Certified.
Bufexamac
Bufexamac is a selective ?b HDAC (HDAC6, HDAC10) and LTA4H dual inhibitor, with K d s of 0.53 μM and 0.22 μM for HDAC6 and HDAC10. Bufexamac is a nonsteroida anti-inflammatory drug [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bufexamic acid. CAS No. 2438-72-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0494.
Bufexamac
Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.Bufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Common brand names include Paraderm and Parfenac. It was withdrawn in Europe because of allergic reactions. Synonyms: Benzeneacetamide, 4-butoxy-N-hydroxy-; 4-Butoxy-N-hydroxybenzeneacetamide; Acetohydroxamic acid, 2-(p-butoxyphenyl)-; 2-(4-Butoxyphenyl)acetohydroxamic acid; 2-(p-Butoxyphenyl)acetohydroxamic acid; 4-Butoxyphenylacethydroxamic acid; Anderm; Bufexamic acid; CP 1044J3; Droxarol; Droxaryl; Feximac; Flogocid; Flogocid N plastigel; Malipuran; Mofenar; Norfemac; p-Butoxyphenylacethydroxamic acid; p-Butoxyphenylacetohydroxamic acid; Parfenac; Parfenal; Trolab. Grades: >98%. CAS No. 2438-72-4. Molecular formula: C12H17NO3. Mole weight: 223.27.
Bufexamac
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C12H17NO3. CAS No. 2438-72-4. Prepack ID 50692579-1g. Molecular Weight 223.27. See USA prepack pricing.
Bufexamac
Bufexamac is a specific inhibitor of class IIB histone deacetylases (HDAC6 and HDAC10). Bufexamac is a non-steroidal anti-inflammatory drug used topically as well as rectally. Formulations containing Bufexamac is used by many patients with eczematous disorders as an alternative to topical corticosteroids. Group: Biochemicals. Alternative Names: 4-Butoxy-N-hydroxy Benzene acetamide; 2- (p-Butoxyphenyl) acetohydroxamic Acid; 4-Butoxyphenylacet hydroxamic Acid; Anderm; Bufexamic Acid; CP 1044J3; Droxarol; Droxaryl; Feximac; Flogocid; Flogocid N plastigel; Malipuran; Mofenar; Norfemac; Parfenac; Parfenal; Trolab; p-Butoxyphenylacet hydroxamic Acid; p-Butoxyphenylaceto hydroxamic Acid. Grades: Highly Purified. CAS No. 2438-72-4. Pack Sizes: 500mg. US Biological Life Sciences.
Buffered oxide etchant (BOE) 6:1 with surfactant. Group: Electronic materials.
Buffer HF improved
Buffer HF improved. Group: Electronic materials.
Buffer pH-10
Buffer pH-10. Product ID: 1-01337.
Buffer pH-4
Buffer pH-4. Product ID: 1-01335.
Buffer pH-7
Buffer pH-7. Product ID: 1-01336.
Buflomedil
Buflomedil is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. Uses: Vasodilator agents. Synonyms: 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-; 2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone; 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanon; 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone. Grades: > 95%. CAS No. 55837-25-7. Molecular formula: C17H25NO4. Mole weight: 307.39.
Buflomedil hydrochloride
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H25NO4 ·HCl. CAS No. 55837-25-7. Prepack ID 23687393-5g. Molecular Weight 343.85. See USA prepack pricing.
Buflomedil hydrochloride
Buflomedil hydrochloride, a vasodilator agent, is an orally active α1A-adrenoceptor antagonist with K i s of 4.06 μM and 6.84 μM for α1A-AR and α1B-AR, respectively. Buflomedil hydrochloride can be used for the study of peripheral circulatory disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35543-24-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0484.
Buflomedil HCl is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease. Uses: Vasodilator agents. Synonyms: Buflomedil hydrochloride; Buflomedil HCl; 35543-24-9; Fonzylane; Loftyl; Buflomedil (hydrochloride); 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone hydrochloride; Buflomedil hydrochloride, European Pharmacopoeia (EP) Reference Standard; 1-BUTANONE, 4-(1-PYRROLIDINYL)-1-(2,4,6-TRIMETHOXYPHENYL)-, HYDROCHLORIDE; Buflomedil for peak identification, European Pharmacopoeia (EP) Reference Standard. Grades: >98%. CAS No. 35543-24-9. Molecular formula: C17H25NO4.HCl. Mole weight: 343.85.
Buflomedil impurity (o-desmethyl)
Buflomedil impurity (o-desmethyl) is a biomedical product used in drug analysand pharmaceutical therapy. This impurity is derived from Buflomedil is a drug used to treat peripheral vascular diseases like Raynaud's phenomenon and intermittent claudication. Its inclusion aids in the identification and characterization of Buflomedil's metabolites, facilitating comprehensive drug development and therapeutic efficacy assessment. Synonyms: 70585-57-8; Buflomedil impurity (o-desmethyl)1-(2-hydroxy-4,6-dimethoxyphenyl)-4-pyrrolidin-1-ylbutan-1-one;hydrochlorideo-Desmethyl-Buflomedil Hydrochloride4-(Pyrrolidin-1-yl)-1-(2-hydroxy-4,6-dimethoxyphenyl)butan-1-one Hydrochloride (o-Desmethyl-Buflomedil Hydrochloride). Grades: > 95%. CAS No. 70585-57-8. Molecular formula: C17H26NO3. Mole weight: 292.40.
Bufogenin (Resibufogenin, Recibufogenin)
Bufogenin (Resibufogenin, Recibufogenin). Group: Biochemicals. Alternative Names: Resibufogenin; Respigon. Grades: Plant Grade. CAS No. 465-39-4. Pack Sizes: 20mg. Molecular Formula: C24H32O4, Molecular Weight: 384.507999999999. US Biological Life Sciences.
Worldwide
Buforin-1
The source of Buforin-1 is Bufo gargarizans. Buforin I is generated from histone H2A by pepsin-directed proteolysis in the cytoplasm of gastric gland cells. After secretion into the gastric lumen, buforin I remains adhered to the mucous biofilm that lines the stomach, thus providing a protective antimicrobial coat. Buforins also are known to possess anti-endotoxin and anticancer activities, thus making these peptides attractive reagents for pharmaceutical applications.
Buforin-2
Buforin II is a highly potent antimicrobial peptide which was derived from buforin I, a peptide isolated from the stomach of the Bufo gargarizans. Buforin II is an α-helical antimicrobial peptide, however it has far stronger antimicrobial activity against a broad spectrum of microorganisms compared with other α-helical antimicrobial peptides. Grades: >95% by HPLC. Mole weight: 2434.85.
Buforin-EC
Buforin-EC was found in Euphlyctis cyanophlyctis. It has antibacterial activity against E.coli HP101BA (MIC=9.6 μM), K.pneumoniae PTCC1388 (MIC=10.6 μM), M.luteus PTCC1625 (MIC=6.0 μM) and S.aureus PTCC1431 (MIC=8.1 μM). Buforin-EC has no or very limited (<3%) hemolytic activity at concentrations of 15 μg/ml and 60 μg/ml, respectively.
Buforin I
Buforin I is a 39-amino acid AMP that was first isolated from the stomach tissue of the Asian toad Bufo gargarizans. Compared with other amphibian AMPs, such as magainin 2, buforin I shows much stronger antimicrobial activities in vitro against a broad spectrum of microorganisms. Buforins have anti-endotoxin and anticancer activities. Synonyms: H-Ala-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-Gly-Asn-Tyr-OH; L-alanyl-glycyl-L-arginyl-glycyl-L-lysyl-L-glutaminyl-glycyl-glycyl-L-lysyl-L-valyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-seryl-L-seryl-L-arginyl-L-alanyl-glycyl-L-leucyl-L-glutaminyl-L-phenylalanyl-L-prolyl-L-valyl-glycyl-L-arginyl-L-valyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-glycyl-L-asparagyl-L-tyrosine. Grades: ≥90% by HPLC. CAS No. 173010-28-1. Molecular formula: C184H318N70O47. Mole weight: 4262.93.
Buforin II
It is a 21 amino acid peptide derived from Buforin I peptide that is isolated from the Asian toad Bufo gargarizans. It has anti-microbial activity by penetrating bacteria and inhibiting cellular functions. Compared with magainin 2, It binds DNA and RNA from E.coli with a much greater affinity. It is also considered to be a cell-delivery peptide and has been shown to deliver SiRNAs into cells followed by effective mRNA degradation. Synonyms: H-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-OH; Buforin; L-Threonyl-L-arginyl-L-seryl-L-seryl-L-arginyl-L-alanylglycyl-L-leucyl-L-glutaminyl-L-phenylalanyl-L-prolyl-L-valylglycyl-L-arginyl-L-valyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-arginyl-L-lysine; Buforin 2. Grades: ≥95%. CAS No. 172998-24-2. Molecular formula: C106H184N40O26. Mole weight: 2434.88.
Buformin-d9
Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase. Group: Biochemicals. Alternative Names: N-Butyl-d9-idodicarbonimidic Diamide; 1-Butyl-d9-biguanide; 1-Butylbiguanide-d9; Buformine-d9; Butformin-d9; Butylbiguanid-d9e; Butyldiguanid-d9e; DBV-d9; Dibetos B-d9; Glybigid-d9; H 224-d9; N1-Butylbiguanide-d9; W 37-d9. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Buformin hydrochloride
Buformin hydrochloride (1-Butylbiguanide hydrochloride), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin hydrochloride also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Butylbiguanide hydrochloride. CAS No. 1190-53-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-B2099A.
Buformin hydrochloride
Buformin is a potent AMPK activator and acts as an orally active biguanide antidiabetic agent. Synonyms: Imidodicarbonimidic diamide, N-butyl-, hydrochloride (1:x); Biguanide, 1-butyl-, hydrochloride; Imidodicarbonimidic diamide, N-butyl-, hydrochloride; Adebit; Butylbiguanide hydrochloride; Silubin; Silubin-retard; 1-Butylbiguanide hydrochloride (1:x); Buformine hydrochloride (1:x); Butylbiguanide hydrochloride (1:x). Grades: ≥95%. CAS No. 15537-73-2. Molecular formula: C6H15N5.xHCl. Mole weight: 157.22 (free base).
Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase. Group: Biochemicals. Alternative Names: N-Butylidodicarbonimidic Diamide Hydrochloride; 1-Butylbiguanide Hydrochloride; 1-Butylbiguanide Hydrochloride; Buformine; Butformin; Butylbiguanide; Butyldiguanide; DBV; Dibetos B; Glybigid; Panformin; Sindiatil; Tidemol; Ziavetine. Grades: Highly Purified. CAS No. 1190-53-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Bufotalin
Bufotalin. Group: Biochemicals. Alternative Names: Bufotaline. Grades: Plant Grade. CAS No. 471-95-4. Pack Sizes: 20mg. Molecular Formula: C26H36O6, Molecular Weight: 444.56. US Biological Life Sciences.
Worldwide
Bufotaline
Bufotaline. Group: Biochemicals. CAS No. 471-95-4. Pack Sizes: 5mg. US Biological Life Sciences.