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| Product | Description | |
|---|---|---|
| Borrelidin | Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei[1]. Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC50 of 24 ?M[2]. Borrelidin is a potent angiogenesis inhibitor, with an IC50 of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells[3]. Borrelidin has strong antimalarial activities, with IC50s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively[4]. Uses: Scientific research. Group: Natural products. Alternative Names: Treponemycin. CAS No. 7184-60-3. Pack Sizes: 500 ?g; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6742. |  |
| Borrelidin | Borrelidin is a macrolide antibiotic produced by Streptomyces rochei and Streptomy- ces sp.C 2989. It has anti-gram-positive bacteria, Borrelia, Cryptococcus neoformans, Tetrahymena gili and Trichomonas vaginalis. It has antiviral and antitumor activity. It can inhibit threonyl tRNA synthetase and protein synthesis. Synonyms: (-)-borrelidin. Grade: >98%. CAS No. 7184-60-3. Molecular formula: C28H43NO6. Mole weight: 489.64. |  |
| Borrelidin | from Streptomyces parvulus, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989) | Borrelidin is an unusual nitrile containing metabolite isolated from Streptomyces. Originally discovered as active against against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery displaying activity against drug-resistant Plasmodia. Group: Biochemicals. Alternative Names: Treponemycin, Antibiotic U 78548, Antibiotic C2989. Grades: Highly Purified. CAS No. 7184-60-3. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| Borrelidin (Treponemycin, U 78548, C2989) | Macrolide antibiotic. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50=0.8nM). Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Blocks the formation of spontaneous lung metastases of B16-BL6 melanoma cells. Cyclin-dependent kinase (CDK) inhibitor. Antiviral. Antimalarial. Group: Biochemicals. Grades: Highly Purified. CAS No. 7184-60-3. Pack Sizes: 500ug, 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Bortezomib | Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome ( K i =0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PS-341; LDP-341; NSC 681239. CAS No. 179324-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10227. | |
| Bortezomib | Bortezomib is a potent, reversible and selective 20S proteasome inhibitor with a Ki of 0.6 nM. It is an antineoplastic agent that is used in treatment of refractory multiple myeloma and certain lymphomas. Synonyms: PS-341; PS 341; PS341; LDP 341; LDP-341; LDP341; MLN341; MLN-341; MLN 341; B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; Velcade; ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid; N-[(1R)-1-(Dihydroxyboryl)-3-methylbutyl]-Nα-(2-pyrazinylcarbonyl)-L-phenylalaninamide. Grade: >98%. CAS No. 179324-69-7. Molecular formula: C19H25BN4O4. Mole weight: 384.24. | |
| Bortezomib | It has a role as an antineoplastic agent, a proteasome inhibitor, a protease inhibitor and an antiprotozoal drug. Alternative Names: Velcade. PS-341. Bortezomib (PS-341). CAS No. 179324-69-7. Product ID: API179324697. Molecular formula: C19H25BN4O4. Mole weight: 384.2. SMILES: B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O. Appearance: White crystalline powder. Category: Anti-Tumor APIs. |  |
| Bortezomib-d15 | Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome with Ki of 0.6 nM. It binds the β5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. Bortezomib blocks the degradation of tumor-suppressing and proapoptotic proteins to induce cell cycle arrest and apoptosis in cancer cell lines. New studies show that bortezomib may potentially help recover from vincristine treatment in treating acute lymphoblastic leukemia, when replacing vincristine in the process. Synonyms: LDP-341-d5; MG-341-d5; PS-341-d5. Grade: ≥99% atom D. Molecular formula: C57H54D15B3N12O9. Mole weight: 1113.76. | |
| Bortezomib-[d5] | Bortezomib-[d5] is the labelled analogue of Bortezomib. Bortezomib is a proteasome inhibitor with an antineoplastic activity used to treat relapsed multiple myeloma and mantle cell lymphoma. Synonyms: Bortezomib-d5; B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid-d5; [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid-d5; Velcade-d5; Radiciol-d5; NSC 681239-d5; DPBA-d5; PS 341-d5; Radiciol-d5; Velcade-d5. Grade: >95%. CAS No. 1133706-15-6. Molecular formula: C19H20D5BN4O4. Mole weight: 389.28. | |
| Bortezomib, deuterated (Velcade-deuterated, [ (1R) -3-Methyl-1- [ [ (2S) -1-oxo-3-phenyl-2- [ (pyrazinylcarbonyl) amino] propyl] amino] butyl] -boronic Acid-deuterated) | Bortezomib is the first proteasome inhibitor to be approved b the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Group: Biochemicals. Alternative Names: Velcade-deuterated, [ (1R) -3-Methyl-1- [ [ (2S) -1-oxo-3-phenyl-2- [ (pyrazinylcarbonyl) amino] propyl] amino] butyl] -boronic Acid-deuterated. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bortezomib, Free Base (Velcade, MG-341, PS-341, [ (1S) -3-methyl-1- [ [ (2R) -3-phenyl-2- (pyrazine-2-carbonylamino) propanoyl] amino] butyl] boronic Acid) | Bortezomib is the active ingredient in the drug sold under the trade name Velcade®. This drug has been approved in at least one country to treat multiple myeloma. It is a potent (Ki, 0.6nM), specific and reversible proteasome inhibitor. There is not any significant inhibitory activity against other enzymes or receptors. In a study with the National Cancer Institute's panel of 60 human cell lines, Bortezomib showed a mean IC50 of 7nM as tested by SRB analysis. Group: Biochemicals. Grades: Highly Purified. CAS No. 179324-69-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Bortezomib Impurity 10 | Bortezomib Impurity 10 is an impurity of bortezomib, a drug used in the biomedical industry for therapy purposes. Bortezomib is a potent anticancer drug mainly used in the therapy of multiple myeloma. Synonyms: 2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-. Grade: > 95%. CAS No. 390800-88-1. Molecular formula: C57H69B3N12O9. Mole weight: 1098.69. | |
| Bortezomib Impurity 12 | Bortezomib Impurity 12 is an impurity of Bortezomib. Synonyms: (R)-Hydroperoxy Des(boric Acid) Bortezomib; N-((S)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-. Grade: > 95%. CAS No. 886979-78-8. Molecular formula: C19H24N4O4. Mole weight: 372.43. | |
| Bortezomib Impurity 13 | Bortezomib Impurity 13 is an impurity of Bortezomib, a pharmaceutical agent primarily indicated in the therapy of multiple myeloma and mantle cell lymphoma. Synonyms: 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-; N-((S)-1-(((S)-1-hydroperoxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide. Grade: > 95%. CAS No. 886979-81-3. Molecular formula: C19H24N4O4. Mole weight: 372.43. | |
| Bortezomib Impurity 16 | Bortezomib Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((S)-3-methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-16-0. Molecular formula: C19H25BN4O4. Mole weight: 384.24. Catalog: APB1132709160. | |
| Bortezomib Impurity 24 | Bortezomib Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1255646-95-7. Molecular formula: C17H18N2O3. Mole weight: 298.34. Catalog: APB1255646957. | |
| Bortezomib Impurity 4 | Bortezomib Impurity 4 is an impurity of Bortezomib. Synonyms: N(1-(3-Methylbutanamido) N(1-Des(boric Acid)) Bortezomib; (S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grade: > 95%. CAS No. 862894-96-0. Molecular formula: C19H22N4O3. Mole weight: 354.41. | |
| Bortezomib Impurity 7 | An impurity of Bortezomib. Bortezomib is a proteasome inhibitor primarily used in the treatment of multiple myeloma (MM) and mantle cell lymphoma (MCL). Synonyms: (R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic acid; Bortezomib Related Compound A. Grade: ≥95%. Molecular formula: C10H16BN3O3. Mole weight: 237.07. | |
| Bortezomib Impurity 9 | Bortezomib Impurity 9 is an impurity of Bortezomib and a tripeptide boronic acid proteasome inhibitor used as an antitumor agent. Synonyms: N-(2-Pyrazinylcarbonyl)-L-phenylalanyl-N-[(1R)-1-borono-3-methylbutyl]-L-phenylalaninamide ; ((R)-3-Methyl-1-((S)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic Acid. Grade: > 95%. CAS No. 1194235-41-0. Molecular formula: C28H34BN5O5. Mole weight: 531.42. | |
| Bortezomib Impurity B | Bortezomib Impurity B is used for the synthesis of Bortezomib. Synonyms: N-(2-pyrazinylcarbonyl)-L-phenylalanine; 3-Phenyl-2-[(pyrazine-2-carbonyl)amino]propionic Acid; (S)-3-Phenyl-2-(pyrazine-2-carbonylamino)propanoic Acid. Grade: 98% by HNMR. CAS No. 114457-94-2. Molecular formula: C14H13N3O3. Mole weight: 271.28. | |
| Bortezomib Impurity F | Bortezomib Impurity F is used for the synthesis of Bortezomib. Synonyms: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester; N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester; N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester. Grade: > 95%. CAS No. 73058-37-4. Molecular formula: C15H15N3O3. Mole weight: 285.31. | |
| Bortezomib Impurity G | Bortezomib Impurity G is an impurity of the acclaimed drug Bortezomib, a drug tailored towards the affliction of multiple myeloma. Synonyms: (S)-Hydroxy Des(boric Acid) Bortezomib; N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide. Grade: > 95%. CAS No. 289472-81-7. Molecular formula: C19H24N4O3. Mole weight: 356.43. | |
| Bortezomib Impurity G | Bortezomib Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((S)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.24. Catalog: APB1132709148. | |
| Bortezomib Impurity H | Bortezomib Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((R)-3-methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.24. Catalog: APB1132709159. | |
| Bortezomib Impurity H | Bortezomib Impurity H is an impurity of Bortezomib, a therapeutic agent for treating multiple myeloma and mantle cell lymphoma. Synonyms: (S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide. Grade: > 95%. CAS No. 1446194-56-4. Molecular formula: C19H24N4O2. Mole weight: 340.43. | |
| Bortezomib Impurity (R,R-Isomer) | Bortezomib Impurity (R,R-Isomer) is a diastereomer of Bortezomib. Synonyms: (1R,2R)-Bortezomib; B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid. Grade: 98% by HPLC. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.25. | |
| Bortezomib Impurity (R,S-Isomer) | Bortezomib Impurity (R,S-Isomer) is a diastereomer of Bortezomib. Synonyms: (1S,2R)-Bortezomib; B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride. Grade: > 95%. CAS No. 1132709-16-0. Molecular formula: C19H25BN4O4. Mole weight: 384.25. | |
| Bortezomib Liposome (PEGylated) | Bortezomib (BTZ) is a proteasome inhibitor used to treat various malignancies, including lung cancer, prostate cancer, colorectal cancer, breast cancer, etc. This product is a pre-formulated liposome encapsulating Bortezomib. It is only for research purposes. Group: Drug-loaded liposome. |  |
| Bortezomib Pinanediol Ester | Bortezomib-pinanediol is a prodrug of Bortezomib and a proteasome inhibitor. Synonyms: N-((S)-1-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate; Bortezomib Pinanediol Impurity. Grade: 97+%. CAS No. 205393-22-2. Molecular formula: C29H39BN4O4. Mole weight: 518.46. | |
| Bortezomib USP Impurity G | Bortezomib USP Impurity G is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Synonyms: (1S,2S)-Bortezomib; ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. Grade: 95%. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.243. | |
| Bortezomib USP Related Compoud B | Bortezomib USP Related Compoud B is an impurity of the acclaimed drug Bortezomib, which is a drug tailored towards the affliction of multiple myeloma. Synonyms: Bortezomib Amide Impurity; N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grade: 98% by HPLC. CAS No. 289472-80-6. Molecular formula: C14H14N4O2. Mole weight: 270.29. | |
| Borussertib | Borussertib is a covalent-allosteric Akt inhibitor with IC50 of 0.8 nM. Borussertib displays antitumor activity in combination with the MEK inhibitor trametinib in patient-derived xenograft models and provides a starting point for further pharmacokinetic/dynamic optimization. CAS No. 1800070-77-2. Molecular formula: C36H32N6O3. Mole weight: 596.68. | |
| Borussertib | Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1800070-77-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-122913. | |
| BOS172722 | BOS172722 is a potent and selective monopolar spindle 1 (MPS1) checkpoint inhibitor with IC50 of 11 nM. Synonyms: BOS-172722; BOS 172722; N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine. CAS No. 1578245-44-9. Molecular formula: C24H30N8O. Mole weight: 446.55. | |
| BOS-318 | BOS-318 is a potent, slowly dissociating, highly selective, and cell-permeable furin inhibitor with IC50 value of 1.9 nM. BOS-318 protects ENaC from subsequent activation by neutrophil elastase. BOS-318 can be used for the rsearch for CF lung disease[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387633-15-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147140. | |
| Boscalid | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. Alternative Names: 3-Pyridinecarboxamide, 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)-, Nicobifen, Endura, Filan, F 510, 2-Chloro-N-(4'-chlorobiphenyl-2-yl)nicotinamide, Cantus, BAS 510F, Boscalid, Emerald, Emerald (fungicide). | |
| Boscalid | Boscalid is an anti-fungal agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 188425-85-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-119976. | |
| Boscalid Metabolite M510F01 | analytical standard. Group: Pesticides & metabolites standards. | |
| Bosentan | Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Synonyms: Ro 47-0203. Grade: >98%. CAS No. 147536-97-8. Molecular formula: C27H29N5O6S. Mole weight: 551.61. | |
| Bosentan | 1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C27H29N5O6S. CAS No. 147536-97-8. Prepack ID 54399509-1g. Molecular Weight 551.61. See USA prepack pricing. |  |
| Bosentan | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan | A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N- [6- (2-hydroxyethoxy) -5- (o-methoxyphenoxy) -2- (2-pyrimidinyl) -4-pyrimidinyl] benzenesulfonamide; Actelion; Ro 47-0203; Ro 47-0203/039; Tracleer. Grades: Highly Purified. CAS No. 147536-97-8. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C27H29N5O6S, Molecular Weight: 551.62. US Biological Life Sciences. | Worldwide |
| Bosentan | Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 147536-97-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013. | |
| Bosentan-[13C2,d4] | Bosentan-[13C2,d4] is the labeled analogue of Bosentan, a mixed endothelin receptor antagonist used as a vasodilator. Synonyms: 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy-1,2-13C2-1,1,2,2-d4)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide; 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy-13C2,d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N-[6-(2-hydroxyethoxy-13C2,d4)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide; Actelion-13C2,d4; Ro 47-0203-13C2,d4; Ro 47-0203/039-13C2,d4; Tracleer-13C2,d4; Bosentan-13C2,d4. Grade: >95%. Molecular formula: C25[13C]2H25D4N5O6S. Mole weight: 557.62. | |
| Bosentan-[d4] | Bosentan-[d4] is the labelled analogue of Bosentan. Bosentan is an endothelin receptor antagonist indicated for pulmonary artery hypertension (PAH). Synonyms: Bosentan D4; 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N-[6-(2-hydroxyethoxy-d4)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide; Actelion-d4; Ro 47-0203-d4; Tracleer-d4. Grade: ≥96% by HPLC; ≥99% atom D. CAS No. 1065472-77-6. Molecular formula: C27H25D4N5O6S. Mole weight: 555.65. | |
| Bosentan-d4 (4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide) | A labeled mixed endothelin receptor antagonist. Used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bosentan hydrate | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H29N5O6S. H2O. CAS No. 157212-55-0. Prepack ID 20114584-1g. Molecular Weight 569.63. See USA prepack pricing. | |
| Bosentan hydrate | Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 157212-55-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013A. | |
| Bosentan hydrate | Bosentan inhibits the presser response to big ET-1 both after i.v. and oral administration, with a long duration of action and no intrinsic agonist activity. Synonyms: Ro 47-0203; Ro 470203; Ro470203; Ro-470203. Grade: >98%. CAS No. 157212-55-0. Molecular formula: C27H29N5O6S.H2O. Mole weight: 569.63. | |
| Bosentan Hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrates. Alternative Names: Bosentan monohydrate,Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-, hydrate (1:1), Bosentan hydrate, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-, monohydrate (9CI). | |
| Bosentan Hydrate | Bosentan Hydrate. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide Hydrate (1:1). Grades: Highly Purified. CAS No. 157212-55-0. Pack Sizes: 25mg. Molecular Formula: C27H31N5O7S, Molecular Weight: 569.63. US Biological Life Sciences. | Worldwide |
| Bosentan impurity 1 | Bosentan impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1065472-77-6. Molecular formula: C27H25D4N5O6S. Mole weight: 555.64. Catalog: APB1065472776. | |
| Bosentan Impurity 1 | Bosentan Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.17. Catalog: APB150728135. | |
| Bosentan Impurity 3 | Bosentan Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butyl)-N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.01. Catalog: APB150727063. | |
| Bosentan Impurity D | Bosentan Impurity D is an impurity of Bosentan. Synonyms: O-Deshydroxyethyl Bosentan; N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide; 4-tert-Butyl-N-[6-hydroxy-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide. Grade: > 95%. CAS No. 174227-14-6. Molecular formula: C25H25N5O5S. Mole weight: 507.57. | |
| Bosentan Related Compound 1 | Bosentan Related Compound 1 is an exquisite biomedical concoction used in the research of the complex ailment known as pulmonary arterial hypertension. Functioning as a highly discerning antagonist of the endothelin receptor, it proficiently curbs the constriction. Synonyms: 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine; Bosentan Related Compound D; 4,6-Dichloro-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)pyrimidine; Bosentan Related Compound D USP. Grade: > 95%. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.18. | |
| Bosentan Related Compound 2 | Bosentan Related Compound 2 is an intermediate as well as a degradation impurity of the endothelin receptor antagonist Bosentan. Synonyms: 4-tert-Butylbenzenesulfonamide; 4-(1,1-Dimethylethyl)benzenesulfonamide; p-tert-butyl-Benzenesulfonamide; NSC 9911. Grade: > 95%. CAS No. 6292-59-7. Molecular formula: C10H15NO2S. Mole weight: 213.30. | |
| Bosentan Related Compound 3 | Bosentan Related Compound 3 is an intermediate of Bosentan. Synonyms: N-[6-Chloro-5-(2-methoxyphenoxy)-(2,2-bipyrimidine)4-4-yl]-(1,1-dimethylethyl)-benzenesulfonamide; 4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzeneSulfonamide. Grade: > 95%. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.02. | |
| Bosentan Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound C | Bosentan Related Compound C is an impurity of Bosentan. Synonyms: N,N'-[1,2-Ethanediylbis[oxy[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-6,4-diyl]]]bis[4-(1,1-dimethylethyl)-benzenesulfonamide; 1,2-Bis({6-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl}oxy)ethane; Bosentan dimer. Grade: > 95%. CAS No. 1097263-60-9. Molecular formula: C52H52N10O10S2. Mole weight: 1041.18. | |
| Bosentan Related Compound D | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bosentan Related Compound E | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Boserolimab | Boserolimab (MK-5890) is a humanized agonist monoclonal antibody that binds to CD27 to provide a costimulatory signal that enhances T-cell - mediated responses [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MK-5890. CAS No. 2444297-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990018. | |
| Boss Fittings | Boss Fittings. Group: Polymers. |  |
| Bostrycin | Bostrycin is a scallion antibiotic produced by Bostrychonema alpestre. It has anti-gram-positive bacteria, negative bacteria, mycobacteria, Candida albicans and other fungi activity, and has inhibitory effect on S-189 and Friend leukemia cells. Synonyms: Rhodosporin. Grade: ≥95%. CAS No. 21879-81-2. Molecular formula: C16H16O8. Mole weight: 336.29. | |
| Bosutinib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Bosutinib | A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; SKI 606. Grades: Highly Purified. CAS No. 380843-75-4. Pack Sizes: 5mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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