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| Product | Description | |
|---|---|---|
| Bronopol | Pesticides & Metabolites; Standards for Environmental Regulatory Methods; Pesticides & Metabolites. Uses: For analytical and research use. Group: Reagents. CAS No. 52-51-7. IUPAC Name: 2-bromo-2-nitropropane-1,3-diol. |  |
| Bronopol (2-Bromo-2-nitro-1,3-propanediol) | 100g Pack Size. Group: Antibiotics, Research Organics & Inorganics. Formula: C3H6BrNO4. CAS No. 52-51-7. Prepack ID 65898637-100g. Molecular Weight 199.99. See USA prepack pricing. |  |
| Bronopol 50% Liquid | Bronopol 50% Liquid. |  |
| Bronopol IP/BP | Bronopol IP/BP. CAS No. 52-51-7. Molecular formula: C3H6BrNO4. | |
| Brontictuzumab | Brontictuzumab (OMP 52M51) is a monoclonal antibody (MAb) that inhibits Notch1 signal. Brontictuzumab selectively binds the negative regulatory region of the Notch1. Brontictuzumab inhibits tumor cell proliferation. Brontictuzumab can be used in the research of leukemia and lymphoma [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OMP 52M51; Anti-Human NOTCH1 Recombinant Antibody. CAS No. 1447814-75-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99258. |  |
| Bronze gauze, alloy 220, 100 mesh woven from 0.11mm (0.0045in) in dia wire | Bronze gauze, alloy 220, 100 mesh woven from 0.11mm (0.0045in) in dia wire. Group: Alloys. |  |
| Bronze gauze, alloy 220, 150 mesh woven from 0.066mm (0.0026in) in dia wire | Bronze gauze, alloy 220, 150 mesh woven from 0.066mm (0.0026in) in dia wire. Group: Alloys. | |
| Bronze gauze, alloy 220, 200 mesh woven from 0.053mm (0.0021in) in dia wire | Bronze gauze, alloy 220, 200 mesh woven from 0.053mm (0.0021in) in dia wire. Group: Alloys. | |
| Bronze gauze, alloy 220, 20 mesh woven from 0.41mm (0.016in) in dia wire | Bronze gauze, alloy 220, 20 mesh woven from 0.41mm (0.016in) in dia wire. Group: Alloys. | |
| Bronze gauze, alloy 220, 40 mesh woven from 0.25mm (0.01in) in dia wire | Bronze gauze, alloy 220, 40 mesh woven from 0.25mm (0.01in) in dia wire. Group: Alloys. | |
| Bronze gauze, alloy 220, 60 mesh woven from 0.19mm (0.0075in) in dia wire | Bronze gauze, alloy 220, 60 mesh woven from 0.19mm (0.0075in) in dia wire. Group: Alloys. | |
| Bronze gauze, alloy 220, 80 mesh woven from 0.14mm (0.0055in) in dia wire | Bronze gauze, alloy 220, 80 mesh woven from 0.14mm (0.0055in) in dia wire. Group: Alloys. | |
| Bronze powder, -100 mesh, 99.0% (metals basis) | Bronze powder, -100 mesh, 99.0% (metals basis). Group: Alloys. | |
| Bronze Powders 7440-50-8 | Bronze Powders - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| BroP | BroP. Group: Biochemicals. Alternative Names: Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate. Grades: Highly Purified. CAS No. 50296-37-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C6H18BrF6N3P2. US Biological Life Sciences. |  Worldwide |
| BrOP | Synonyms: BroP Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate; Bromotris(dimethylamino)phosphonium hexafluorophosphate; ; BROP; BROMO-TRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE (BROP); BROP BROMOTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; ACMC-20aljt. Grades: 98% (HPLC). CAS No. 50296-37-2. Molecular formula: C6H18BrF6N3P2. Mole weight: 388.07. |  |
| Broparestrol | Broparestrol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Broparoestrol, Broparestrolum, Broparoestrolum, Broparestrol, Longestrol, Acnestrol, trans-Broparestrol, Broparestrolum [INN-Latin], C22H19Br, broparoestrol, (trans)-isomer, UNII-7U06D381UQ, LN 1643, EINECS 207-537-1, LN 107, CID3032769, LS-68306, 2-Brom-1-(4-ethylphenyl)-1,2-diphenylethylen, (E)-1-(2-Bromo-1,2-diphenylethenyl)-4-ethylbenzene, (E)-1-Bromo-1,2-diphenyl-2-(p-ethylphenyl)ethylene, 1-Bromo-2-p-(ethylphenyl)-1,2-diphenylethylene. Product Category: Heterocyclic Organic Compound. CAS No. 479-68-5. Molecular formula: C22H19Br. Mole weight: 363.296. Purity: 0.96. IUPACName: 1-[(E)-2-bromo-1,2-diphenylethenyl]-4-ethylbenzene. Canonical SMILES: CCC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Br)C3=CC=CC=C3. Density: 1.259g/cm³. ECNumber: 207-537-1. Product ID: ACM479685. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Bropirimine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Bropirimine | Bropirimine is an immunostimulant as well as anticancer agent and has been found to exhibit direct antitumor activity. Synonyms: 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone. Grades: ≥96% by HPLC. CAS No. 56741-95-8. Molecular formula: C10H8BrN3O. Mole weight: 266.09. | |
| Bropirimine | Bropirimine. Group: Biochemicals. Grades: Purified. CAS No. 56741-95-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Brostallicin | Brostallicin, a-bromo-acrylamido tetra-pyrrole derivative, is a second-generation minor groove binder (MGB) structurally related to distamycin A with potential antineoplastic activity. Compared with that of other minor groove binders, this agent appears to bind covalently to DNA in a different manner and its activity does not depend on a functional DNA mismatch repair (MMR) mechanism. Synonyms: 4-[[4-[[4-[[4-(2-bromoprop-2-enoylamino)-1-methylpyrrole-2-carbonyl]amino]-1-methylpyrrole-2-carbonyl]amino]-1-methylpyrrole-2-carbonyl]amino]-N-[2-(diaminomethylideneamino)ethyl]-1-methylpyrrole-2-carboxamide; brostallicin; PNU 166196; PNU-166196; PNU166196. Grades: >98%. CAS No. 203258-60-0. Molecular formula: C30H36BrClN12O5. Mole weight: 723.58. | |
| Brostallicin hydrochloride | Brostallicin is a synthetic, alpha-bromoacrylic, second-generation minor groove binder (MGB), related to distamycin A, with potential antineoplastic activity. Brostallicin binds to DNA minor groove DNA, after having formed a highly reactive glutathione (GSH)-brostallicin complex in the presence of the enzyme glutathione S-transferase (GST), which is overexpressed in cancer cells; DNA replication and cell division are inhibited, resulting in tumor cell death. Compared to typical MGBs, this agent appears to bind covalently to DNA in a different manner and its activity does not depend on a functional DNA mismatch repair (MMR) mechanism. Accordingly, brostallicin may be effective against MMR-defective tumors that are refractory to various anticancer agents. Synonyms: PNU-166196; PNU 166196; PNU166196; 4-(2-bromoacrylamido)-N-(5-(5-(5-(2-guanidinoethylcarbamoyl)-1-methyl- 1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H-pyrrol-3-ylcarbamoyl)-1-methyl-1H- pyrrol-3-yl)-1-methyl-1H-pyrrole-2-carboxamide. CAS No. 203258-38-2. Molecular formula: C30H36BrClN12O5. Mole weight: 760.05. | |
| Brotianide | Brotianide, with anti-fasciolidal activity, is an anthelminthic drug for the treatment of severe infections on animals to remove larvae. Synonyms: [2-bromo-6-[(4-bromophenyl)carbamothioyl]-4-chlorophenyl] acetate; Brotianide; Dirian; Brotianidum [INN-Latin]; Brotianida [INN-Spanish]; UNII-30OGU6XH7S; Brotianide; Dirian; BAY-VA 4059; BAY-VA-4059; BAY-VA4059. Grades: >98%. CAS No. 23233-88-7. Molecular formula: C15H10Br2ClNO2S. Mole weight: 463.568. | |
| Brotizolam Impurity 1 | Brotizolam Impurity 1 is a crucial impurity within the therapy of Brotizolam, which aids in the therapy of insomnia and sleep disorders. Grades: > 95%. CAS No. 1437317-64-0. Molecular formula: C15H12BrClN4OS. Mole weight: 411.71. | |
| Broussonin E | Broussonin E is a phenolic compound and shows anti-inflammatory activity. Broussonin E can suppress inflammation by modulating macrophages activation statevia inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway. Broussonin E can be used for the research of inflammation-related diseases such as atherosclerosis. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 90902-21-9. Molecular formula: C17H20O4. Mole weight: 288.3. Purity: 0.98. IUPACName: 5-[3-(2-hydroxy-4-methoxyphenyl)propyl]-2-methoxyphenol. Canonical SMILES: COC1=CC(=C(C=C1)CCCC2=CC(=C(C=C2)OC)O)O. Product ID: ACM90902219. Alfa Chemistry ISO 9001:2015 Certified. Categories: Broussonneti. | |
| Brown 640 Iron Oxide | Iron Oxide Brown 640 - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Browniine | Browniine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 20-Ethyl-1α,6β,16β-trimethoxy-4-(methoxymethyl)aconitane-7,8,14α-triol. Product Category: Heterocyclic Organic Compound. CAS No. 5140-42-1. Mole weight: 467.6. Purity: 90%+. Product ID: ACM5140421. Alfa Chemistry ISO 9001:2015 Certified. Categories: Brown Line (CTA). | |
| Brown Seaweed P. E. 5% Fucoxanthin UV | Brown Seaweed P. E. 5% Fucoxanthin UV. |  CA, FL & NJ |
| Brown Sugar Flavor Naturome | Brown Sugar Flavor Naturome. CAS No. MIXTURE. Kosher: Y. VIGON Item # 503475. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Broxaldine | Broxaldine (Brobenzoxaldine) is an antiprotozoal agent. Broxaldine inhibits Clostridium difficile with a MIC value of 4 μM, and has antifungal effects. Uses: Designed for use in research and industrial production. Additional or Alternative Names: broxaldine;5,7-Dibromo-2-methylquinoline-8-ol benzoate;5,7-Dibromo-8-benzoyloxy-2-methylquinoline;Brobenzoxaldine;5,7-Bibromo-2-methylquinolin-8-ol;Aids112123;Aids-112123. Product Category: Inhibitors. Appearance: Solid. CAS No. 3684-46-6. Molecular formula: C17H11Br2NO2. Mole weight: 421.087. Purity: 0.995. Canonical SMILES: CC1=NC2=C(OC(C3=CC=CC=C3)=O)C(Br)=CC(Br)=C2C=C1. Product ID: ACM3684466. Alfa Chemistry ISO 9001:2015 Certified. | |
| Broxyquinoline | Broxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes. Synonyms: Broxyquinoline; NSC 1810; NSC-1810; NSC1810; Dibromoxyquinoline; UCB 5055; UCB-5055; UCB5055; Paramibe; Brodiar. Grades: >98%. CAS No. 521-74-4. Molecular formula: C9H5Br2NO. Mole weight: 302.95. | |
| BRP-7 | BRP-7 is a 5-LO activating protein (FLAP) inhibitor. Synonyms: BRP 7; BRP7. CAS No. 612046-20-5. Molecular formula: C26H27ClN2. Mole weight: 403. | |
| BRPF1 (627-746) human | recombinant, expressed in E. coli, ?69% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BRSK1, active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| BRSK2 Active human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Bruceantin | Bruceantin ((-)-Bruceantin) is a quassinoid found in B. javanica. Bruceantin activates caspase signaling pathway, causes the mitochondrial dysfunction, inhibits cell proliferation, induces cell differentiation and apoptosis. Bruceantin exhibits anti-leukemia and antiprotozoal activities[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Bruceantin; NCI165563; NSC165563. CAS No. 41451-75-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0840. | |
| Bruceine A | Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis.IC50 value:Target:Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical findings in a dog with normal ranges of hematological and biochemical values in the blood. Three dogs were infected with B. gibsoni and two of them were treated with bruceine A at a dosage of 6.4 mg/kg/day for 6 days from day 5 post-infection. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 25514-31-2. Molecular formula: C26H34O11. Mole weight: 522.54. Purity: 0.98. Canonical SMILES: CC1=C(C(=O)CC2(C1CC3C45C2C(C(C(C4C(C(=O)O3)OC(=O)CC(C)C)(OC5)C(=O)OC)O)O)C)O. Product ID: ACM25514312. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bruce Inkango. | |
| Bruceine D | Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity. Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 21499-66-1. Molecular formula: C20H26O9. Mole weight: 410.4. Purity: 0.98. Canonical SMILES: CC1=CC(=O)C(C2(C1CC3C45C2C(C(C(C4(C(C(=O)O3)O)O)(OC5)C)O)O)C)O. Product ID: ACM21499661. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bruceol | Synonyms: (-)-Bruceol; 2,12-Epoxy-2H,9H-[2]benzopyrano[4,3-g][1]benzopyran-9-one, 1,3,4,4a,5,12b-hexahydro-1-hydroxy-2,5,5-trimethyl-, [1S-(1α, 2α, 4aβ, 12bβ)]-. CAS No. 33044-74-5. Molecular formula: C19H20O5. Mole weight: 328.36. | |
| Bruceol benzoate | Cas No. 105668-07-3. Molecular formula: C26H24O6. Mole weight: 432.47. | |
| Brucine | Brucine. Group: Biochemicals. Alternative Names: 10,11-Dimethoxystrychnine. Grades: Plant Grade. CAS No. 357-57-3. Pack Sizes: 20mg. Molecular Formula: C23H26N2O4, Molecular Weight: 394.464. US Biological Life Sciences. | Worldwide |
| Brucine 99+% | Brucine 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 357-57-3. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Brucine, anhydrous | Brucine, anhydrous. Group: Biochemicals. Alternative Names: 10,11-Dimethoxystrychnine. Grades: Highly Purified. CAS No. 357-57-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C23H26N2O4. US Biological Life Sciences. | Worldwide |
| Brucine, Anhydrous (10,11-Dimethoxystrychnine) | Brucine, Anhydrous (10,11-Dimethoxystrychnine). Group: Biochemicals. Alternative Names: 10,11-Dimethoxystrychnine. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| Brucine sulfate | Brucine sulfate. Group: Biochemicals. Grades: Highly Purified. CAS No. 4845-99-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: 2 (C23H26N2O4) H2O4S·xH2O. US Biological Life Sciences. | Worldwide |
| Brucine sulfate heptahydrate | Brucine sulfate heptahydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 5787-00-8,652154-10-4. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C23H26N2O4·7H2O·H2O4S. US Biological Life Sciences. | Worldwide |
| Brucite (NIM-GBW03128) | Brucite (NIM-GBW03128). Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS006297. Shipping: Room Temperature. | |
| Bruker quantitative PQ Certified Reference Material | 1H Performance Qualification sample for qNMR in DMSO-d6. Group: Quantitative nmr. | |
| Brunellae Spica Extract | Brunellae Spica Extract. Applications: Used for health care products, dietary supplements, herb medecine and cosmetic industry. Group: Others. Synonyms: Brunellae Spica Extract; Prunella vulgaris Linn. Purity: 10:1 by TLC. Appearance: Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Flower. Species: Prunella vulgaris Linn. Brunellae Spica Extract; Prunella vulgaris Linn.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-141. |  |
| Brupropion hydrochloride | Brupropion hydrochloride. CAS No. 31677-93-7. Product ID: 8-01689. Molecular formula: C13H21Cl2NO. Mole weight: 278.22. |  |
| Brusatol | Brusatol is a triterpenoid isolated from the Brucea javanica plant. Brusatol acts as an Nrf2 inhibitor with anticancer activity. Uses: Anti-tumor. Synonyms: (+)-Brusatol; Yatansin. Grades: >98%. CAS No. 14907-98-3. Molecular formula: C26H32011. Mole weight: 520.53. | |
| Brusatol | Brusatol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 13,20-Epoxy-3,11β,12α-trihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxopicras-3-en-21-oic acid methyl ester;13,20-Epoxy-3,11β,12α-trihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxopicrasa-3-ene-21-oic acid methyl ester;Picras-3-en-21-oicacid,13,20-epoxy-3,11,12-trihydroxy-15-[(3-Methyl-1-oxo-2-buten-1-yl)oxy]-2,16-dioxo-,Methyl ester, (11b,12a,15b)-;NSC 172924;Yatansin;Brustaol. Product Category: Heterocyclic Organic Compound. Appearance: White crystalline powder. CAS No. 14907-98-3. Molecular formula: C26H32O11. Mole weight: 520.53. Purity: 0.98. Canonical SMILES: CC1=C(C(=O)CC2(C1CC3C45C2C(C(C(C4C(C(=O)O3)OC(=O)C=C(C)C)(OC5)C(=O)OC)O)O)C)O. Density: 1.46±0.1 g/cm³ (20 ºC 760 Torr). Product ID: ACM14907983. Alfa Chemistry ISO 9001:2015 Certified. Categories: Brustolina. | |
| Brusatol | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Brusatol | Brusatol (NSC?172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent[1]. Brusatol increases cellular apoptosis[2]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 172924. CAS No. 14907-98-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19543. | |
| Brusatol | Brusatol. Group: Biochemicals. Alternative Names: Yatansin ; 13,20-Epoxy-3,11b,12a-trihydroxy-15b-[(3-methyl-1-oxo-2-butenyl)oxy]-2,16-dioxopicras-3-en-21-oic acid methyl ester. Grades: Highly Purified. CAS No. 14907-98-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C26H32O11. US Biological Life Sciences. | Worldwide |
| Brussel Sprout P.E 10:1 | Brussel Sprout P.E 10:1. | CA, FL & NJ |
| Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT | Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make an antibody agent conjugate (ADC), ABBV-969[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2857037-70-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148820. | |
| Bryostatin 1 | Bryostatin 1. Group: Biochemicals. Grades: Purified. CAS No. 83314-01-6. Pack Sizes: 10ug. US Biological Life Sciences. | Worldwide |
| Bryostatin 1 | ?99%, solid. Group: Fluorescence/luminescence spectroscopy. | |
| Bryostatin 1 | Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BRYOSTATIN 1;BRYO 1;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en;BRYOSTATIN;bryostatin1,0;(26R)-Bryostatin 1;NSC-339555;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester. Product Category: Inhibitors. Appearance: solid. CAS No. 83314-01-6. Molecular formula: C47H68O17. Mole weight: 905.03. Purity: ≥99.0%. Product ID: ACM83314016. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bryostatin 1 | Bryostatin 1, a structurally unique macrolactone marine natural product, is a protein kinase C (PKC) activator that binds with high affinity (Ki = 1.35 nM). Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke. Uses: Adjuvants, immunologic. Synonyms: Bryostatin-1; Bryostatin1; NSC-339555; NSC 339555; NSC339555; AC1L8WCW. Grades: ≥99%. CAS No. 83314-01-6. Molecular formula: C47H68O17. Mole weight: 905.04. | |
| Bryostatin 1 - CAS 83314-01-6 | A macrocyclic lactone with antitumor properties. Group: Fluorescence/luminescence spectroscopy. | |
| Bryostatin 1 (NSC 339555, B705008K112, BRN 4349157) | Bryostatin 1 binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators. Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Group: Biochemicals. Grades: Highly Purified. CAS No. 83314-01-6. Pack Sizes: 10ug, 25ug. US Biological Life Sciences. | Worldwide |
| Bryostatin 2 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Bryostatin 2 | Bryostatin 2, an analog of Bryostatin 1, is an activator of PKC (protein kinase C) with anti-tumor properties. Bryostatin 2 inhibits DNA synthesis at 100 nM in SH-SY5Y human neuroblastoma cells. Synonyms: Bryostatin-2; Bryostatin2; Deacetyl Bryostatin 1; Deacetyl Bryostatin-1; NSC 339554; NSC339554; NSC-339554. Grades: ≥95% by HPLC. CAS No. 87745-28-6. Molecular formula: C45H66O16. Mole weight: 862.99. | |
| Bryostatin 2 | Bryostatin 2. Group: Biochemicals. Grades: Purified. CAS No. 87745-28-6. Pack Sizes: 10ug. US Biological Life Sciences. | Worldwide |
| Bryostatin 3 | Bryostatin 3 has been found to be a potent protein kinase C activator and could probably be useful in studies of emerging cancers. Synonyms: Bryostatin 3; 143370-84-7; (4S, 5S, 7E, 9R, 11Z, 13S, 15S, 17S, 19R, 21R, 25R, 27R, 27aS)-17-(Acetyloxy)-4, 5, 6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-[(1R)-1-hydroxyethyl]-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl-(2E,4E)-2,4-octadienoic acid ester. Grades: ≥95% by HPLC. CAS No. 143370-84-7. Molecular formula: C46H64O17. Mole weight: 888.99. | |
| Bryostatin 3 | Bryostatin 3. Group: Biochemicals. Grades: Purified. CAS No. 143370-84-7. Pack Sizes: 10ug. US Biological Life Sciences. | Worldwide |
| Bryostatin 3 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BS181 | BS-181 is a highly selective CDK inhibitor for CDK7 with an IC(50) of 21 nmol/L. Testing of other CDKs as well as another 69 kinases showed that BS-181 only inhibited CDK2 at concentrations lower than 1 micromol/L, with CDK2 being inhibited 35-fold less potently (IC(50) 880 nmol/L) than CDK7. In MCF-7 cells, BS-181 inhibited the phosphorylation of CDK7 substrates, promoted cell cycle arrest and apoptosis to inhibit the growth of cancer cell lines, and showed antitumor effects in vivo. The drug was stable in vivo with a plasma elimination half-life in mice of 405 minutes after i.p. administration of 10 mg/kg. The same dose of drug inhibited the growth of MCF-7 human xenografts in nude mice. BS-181 therefore provides the first example of a potent and selective CDK7 inhibitor with potential as an anticancer agent. Synonyms: BS-181; BS181; BS 181. CAS No. 1092443-52-1. Molecular formula: C22H32N6. Mole weight: 380.53. | |
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