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| Product | Description | |
|---|---|---|
| Brasiliquinone C | Brasiliquinone C is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis, which has anti-gram-positive bacteria and tumor activity. Synonyms: (3S)-3-ethyl-6-hydroxy-8-methoxy-3,4-dihydrotetraphene-1,7,12(2H)-trione. CAS No. 183201-06-1. Molecular formula: C21H18O5. Mole weight: 350.36. |  |
| Brasiliquinone D | Brasiliquinone D is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis. Molecular formula: C28H29NO8. Mole weight: 507.53. | |
| Brasofensine | Brasofensine is a phenyltropane drug that is developed for the treatment of Parkinson's and Alzheimer's disease. Synonyms: NS-2214; BMS-204756; (E)-1-[(2R,3S)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-N-methoxymethanimine. CAS No. 171655-91-7. Molecular formula: C16H20Cl2N2O. Mole weight: 327.249. | |
| Brassaiopsis Glomerulata P.E. 10:1 | Brassaiopsis Glomerulata P.E. 10:1. |  CA, FL & NJ |
| Brass foil, alloy 260, 0.025mm (0.001in) thick, 15.2x45cm (6.0x18in) | Brass foil, alloy 260, 0.025mm (0.001in) thick, 15.2x45cm (6.0x18in). Group: Alloys. |  |
| Brass foil, alloy 260, 0.025mm (0.001in) thick, 7.2x45cm (3.0x18in) | Brass foil, alloy 260, 0.025mm (0.001in) thick, 7.2x45cm (3.0x18in). Group: Alloys. | |
| Brass foil, alloy 260, 0.25mm (0.01in) thick, 15x45cm (5.9x18in) | Brass foil, alloy 260, 0.25mm (0.01in) thick, 15x45cm (5.9x18in). Group: Alloys. | |
| Brass foil, alloy 260, 0.3mm (0.012in) thick | Brass foil, alloy 260, 0.3mm (0.012in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 0.41mm (0.016in) thick | Brass foil, alloy 260, 0.41mm (0.016in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 0.51mm (0.02in) thick | Brass foil, alloy 260, 0.51mm (0.02in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 0.51mm (0.02in) thick, 15x45cm (5.9x18in) | Brass foil, alloy 260, 0.51mm (0.02in) thick, 15x45cm (5.9x18in). Group: Alloys. | |
| Brass foil, alloy 260, 0.64mm (0.025in) thick | Brass foil, alloy 260, 0.64mm (0.025in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 0.81mm (0.032in) thick | Brass foil, alloy 260, 0.81mm (0.032in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 1.0mm (0.04in) thick | Brass foil, alloy 260, 1.0mm (0.04in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 1.3mm (0.05in) thick | Brass foil, alloy 260, 1.3mm (0.05in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 1.6mm (0.064in) thick | Brass foil, alloy 260, 1.6mm (0.064in) thick. Group: Alloys. | |
| Brass foil, alloy 260, 2.0mm (0.08in) thick | Brass foil, alloy 260, 2.0mm (0.08in) thick. Group: Alloys. | |
| Brass gauze, alloy 260, 100 mesh woven from 0.11mm (0.0045in) dia wire | Brass gauze, alloy 260, 100 mesh woven from 0.11mm (0.0045in) dia wire. Group: Alloys. | |
| Brass gauze, alloy 260, 20 mesh woven from 0.41mm (0.016in) dia wire | Brass gauze, alloy 260, 20 mesh woven from 0.41mm (0.016in) dia wire. Group: Alloys. Molecular formula: 336g/mol. Mole weight: CuPbZn. [Cu].[Zn].[Pb]. InChI=1S/Cu.Pb.Zn. UXNBTDLSBQFMEH-UHFFFAOYSA-N. | |
| Brass gauze, alloy 260, 80 mesh woven from 0.14mm (0.0055in) dia wire; Cu:Zn; 70:30 wt% | Brass gauze, alloy 260, 80 mesh woven from 0.14mm (0.0055in) dia wire; Cu:Zn; 70:30 wt%. Group: Alloys. | |
| Brassicasterol | A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. Brassicasterol can increase accumulation of demosterol, a cholesterol precursor and substrate and inhibit cholesterol formation in HL-60 cells in a dose-dependent manner. It also inhibits the hemolytic activity of pneumolysin from S. pneumoniae. Synonyms: (3β,22E)-Ergosta-5,22-dien-3-ol; 24-Methylcholesta-5,22-dien-3β-ol; Brassicasterin; Ergosta-5,22(E)-dien-3β-ol. Grades: ≥95%. CAS No. 474-67-9. Molecular formula: C28H46O. Mole weight: 398.66. | |
| Brassicasterol | Brassicasterol. Group: Biochemicals. Alternative Names: (3b,22E)-Ergosta-5,22-dien-3-ol; Ergosta-5,22-dien-3b-ol; 24(R)-Methylcholesta-5,22E-dien-3b-ol. Grades: Highly Purified. CAS No. 474-67-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C28H46O. US Biological Life Sciences. |  Worldwide |
| Brassicasterol | Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 ( IC 50 =1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase , slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 474-67-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113289. |  |
| Brassicasterol | Brassicasterol, a metabolite of Ergosterol, plays a role in the inhibitory effect on bladder carcinogenesis promotion via androgen signaling. Brassicasterol shows dual anti-infective properties against HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis, and cardiovascular protective effect. Brassicasterol exerts an anti-cancer effect by dual-targeting AKT and androgen receptor signaling in prostate cancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ergosta-5,22E-dien-3beta-ol; (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(E,1R,4R)-1,4,5-trimethylhex-2-enyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Product Category: Inhibitors. Appearance: Cryst. CAS No. 474-67-9. Molecular formula: C28H46O. Mole weight: 398.66. Purity: 0.98. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Product ID: ACM474679-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Brassicasterol-(2,2',3,4,4',6-D6) | Brassicasterol-(2,2',3,4,4',6-D6) is derived from Brassicasterol (B676850), which is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H40D6O, Molecular Weight: 404.7. US Biological Life Sciences. | Worldwide |
| Brassinazole | Brassinazole is a potent brassinosteroid (BR) biosynthesis inhibitor that has similar structure to pacrobutrazol. Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. It has displayed the ability to induce morphological changes in dark-grown Arabidopsis. It can also induce morphological changes, including dwarfism and altered leaf color and curling. Synonyms: Brassinazole. Grades: ≥98%. CAS No. 224047-41-0. Molecular formula: C18H18ClN3O. Mole weight: 327.8. | |
| Brassinazole | Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 280129-83-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-121161A. | |
| Brassinin | Brassinin is the metabolism of a phytoalexin from Beassica pekinensis (Lour. ) Rupr. [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Brassinine. CAS No. 105748-59-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-111334. | |
| Brassinin | Brassinin is an indoleamine-2,3-dioxygenase inhibitor found in cruciferous vegetables. It induces cell cycle arrest and apoptosis in prostate cancer cells and inhibits DMBA-induced skin tumor formation in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Brassinine; CCG-208623; CCG208623; CCG 208623; HE-005916; HE005916; HE 005916; HE-292778; HE292778; HE292778. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 105748-59-2. Molecular formula: C11H12N2S2. Mole weight: 236.35. Purity: >98%. IUPACName: methyl ((1H-indol-3-yl)methyl)carbamodithioate. Canonical SMILES: S=C(SC)NCC1=CNC2=C1C=CC=C2. Product ID: ACM105748592-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Brassinin | Brassinin. Group: Biochemicals. Alternative Names: N- (1H-Indol-3-ylmethyl) carbamodithioic acid. Grades: Highly Purified. CAS No. 105748-59-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H12N2S2. US Biological Life Sciences. | Worldwide |
| Brassinin | Brassinin is an inhibitor of indoleamine 2,3-dioxygenase (IDO; Ki = 28 μM for human IDO) with antifungal and anticancer activities. Brassinin also inhibits IL-6-inducible STAT3 activation and attenuates tumor growth in a xenograft lung cancer mouse model. Brassinin is found in brassicas. Synonyms: Brassinine; CCG-208623; CCG208623; CCG 208623; HE-005916; HE005916; HE 005916; HE-292778; HE292778; HE292778; Methyl (1H-indol-3-ylmethyl)carbamodithioate. Grades: 98%. CAS No. 105748-59-2. Molecular formula: C11H12N2S2. Mole weight: 236.36. | |
| Brassinolide | 25mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C28H48O6. CAS No. 72962-43-7. Prepack ID 90026901-25mg. Molecular Weight 480.68. See USA prepack pricing. |  |
| Brassinolide | 5mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C28H48O6. CAS No. 72962-43-7. Prepack ID 90026901-5mg. Molecular Weight 480.68. See USA prepack pricing. | |
| Brassinolide | Brassinolide is a predominant plant growth modulator that regulate plant cell elongation. Uses: Scientific research. Group: Natural products. Alternative Names: Brassin lactone. CAS No. 72962-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0273. | |
| Brass plate, alloy 260, 2.4mm (0.093in) thick | Brass plate, alloy 260, 2.4mm (0.093in) thick. Group: Alloys. | |
| Brass plate, alloy 260, 3.18mm (0.125in) thick | Brass plate, alloy 260, 3.18mm (0.125in) thick. Group: Alloys. Molecular formula: 336g/mol. Mole weight: CuPbZn. [Cu].[Zn].[Pb]. InChI=1S/Cu.Pb.Zn. UXNBTDLSBQFMEH-UHFFFAOYSA-N. | |
| Brass plate alloy 260, 6.35mm (0.25in) thick | Brass plate alloy 260, 6.35mm (0.25in) thick. Group: Alloys. | |
| Brass spheres, alloy 260, 12.7mm (0.5in) dia | Brass spheres, alloy 260, 12.7mm (0.5in) dia. Group: Alloys. Molecular formula: 336g/mol. Mole weight: CuPbZn. [Cu].[Zn].[Pb]. InChI=1S/Cu.Pb.Zn. UXNBTDLSBQFMEH-UHFFFAOYSA-N. | |
| Brass spheres, alloy 260, 3.18mm (0.125in) dia | Brass spheres, alloy 260, 3.18mm (0.125in) dia. Group: Alloys. | |
| Brass spheres, alloy 260, 6.35mm (0.25in) dia | Brass spheres, alloy 260, 6.35mm (0.25in) dia. Group: Alloys. | |
| Brazikumab | Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23 , with a K D of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 139; MEDI2070. CAS No. 1610353-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99485. | |
| Brazilin | Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis , and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 474-07-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0072. | |
| Brazilin (Brasilin) | Brazilin (Brasilin). Group: Biochemicals. Grades: Plant Grade. CAS No. 474-07-7. Pack Sizes: 10mg. Molecular Formula: C16H14O5, Molecular Weight: 286.28. US Biological Life Sciences. | Worldwide |
| BRCA1-IN-1 | A novel small-molecule-like BRCA1 inhibitor (IC50= 0.53 μM) (Ki= 0.71 μM). Synonyms: [ (3S) -1, 1-difluoro-3-[3- (1H-indol-3-yl) propanoylamino]-4-oxo-4-[[2-oxo-2- (4-phenylbutylamino) ethyl]amino]butyl]phosphonic acid. CAS No. 1622262-74-1. Molecular formula: C27H33F2N4O6P. Mole weight: 578.54. | |
| BRD0639 | BRD0639 is a potent PRMT5 inhibitor. BRD0639 engages the target in cells, disrupts PRMT5-RIOK1 complexes, and reduces substrate methylation. BRD0639 is a first-in-class PBM-competitive inhibitor that can support studies of PBM-dependent PRMT5 activities and the development of novel PRMT5 inhibitors that selectively target these functions. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BRD0639; BRD 0639; BRD-0639. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2760881-74-9. Molecular formula: C21H22ClN5O4S. Mole weight: 475.95. Purity: >98%. IUPACName: (S)-2-(4-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-(N-(2-(pyridin-2-yl)ethyl)sulfamoyl)phenyl)propanamide. Canonical SMILES: C[C@H](N1C(C=C(Cl)C=N1)=O)C(NC2=CC=C(C)C(S(=O)(NCCC3=NC=CC=C3)=O)=C2)=O. Product ID: ACM2760881749. Alfa Chemistry ISO 9001:2015 Certified. | |
| BRD2 Inhibitor II, BIC1 (BRD2 Bromodomain-Interactive Compound, BIC1, 1-(2-(1H-Benzimidazol-2-ylsulfanyl)ethyl)-3-methyl-1,3-dihydro-2H-benzimidazole-2-thione, 1-(2-(1H-Benzo[d]imidazol-2-ylthio)ethyl)-3-methyl-1H-benzo[d]imidazole-2(3H)-thione) | A cell-permeable benzimidazolyl-benzimidazolothione compound that directly interacts with BRD2-BD1 bromodomain reversibly (=28uM) and blocks the transcriptional activity of BRD2 in COS7 cells expressing Histac-K12 (<10uM). Shown to selectively disrupt BRD2 bromodomain-acetylated histone H4K12 association without modulating H4K12 acetylation; only weakly affect the interaction between the BRDT bromodomain (testis-specific bromodomain-containing protein) and acetylated histone H4. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BRD32048 | The ETV1 transcription factor is phosphorylated downstream of MAPK signaling and is acetylated at lysines 33 and 116 by the histone acetyltransferase p300. BRD32048 is an inhibitor of the ETV1 transcription factor oncoprotein. BRD32048 binds ETV1 directly, modulating both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 is a substituted [1,3,5]triazine derivative that inhibits ETV1 transcriptional activity by binding to ETV1 with KD of 17.1 μM, which reduces p300-dependent acetylation and stability of ETV1. Synonyms: BRD-32048; BRD 32048. Grades: ≥98%. CAS No. 433694-46-3. Molecular formula: C16H22N6O. Mole weight: 314.4. | |
| BRD3308 | BRD3308 is a highly selective HDAC3 inhibitor with IC50 of 54 nM. BRD3308 inhibits pancreatic β-cell apoptosis induced by inflammatory cytokines or glycolipid toxic stress, and increases the release of functional insulin. BRD3308 activates HIV-1 transcription and destroys the HIV-1 incubation period. Synonyms: 4-Acetylamino-N-(2-Amino-4-Fluorophenyl)-Benzamide; CHEMBL4293858; SCHEMBL15551809; BDBM178100. Grades: 98%. CAS No. 1550053-02-5. Molecular formula: C15H14FN3O2. Mole weight: 287.29. | |
| BRD 4354 | BRD 4354 is an HDAC5 and HDAC9 inhibitor (IC50 = 0.85 and 1.88 μM, respectively) displaying >20-fold selectivity for HDAC5/9 over HDAC1/2/3. It also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM). Synonyms: BRD4354; BRD 4354; BRD-4354; 5-Chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-8-quinolinol. Grades: ≥98% by HPLC. CAS No. 315698-07-8. Molecular formula: C21H23ClN4O. Mole weight: 382.89. | |
| BRD4770 | BRD4770 is a novel histone methyltransferase inhibitor. BRD4770 reduced cellular levels of di- and trimethylated H3K9 without inducing apoptosis, induced senescence, and inhibited both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1. ATM-pathway activation, caused by either genetic or small-molecule inhibition of G9a, may mediate BRD4770-induced cell senescence. BRD4770 may be a useful tool to study G9a and its role in senescence and cancer cell biology. Synonyms: BRD4770; BRD-4770; BRD 4770. Grades: 0.98. CAS No. 1374601-40-7. Molecular formula: C25H23N3O3. Mole weight: 413.477. | |
| BRD4884 | BRD4884 is a selective HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 μM for HDAC1, 2, and 3. It possesses preferential binding kinetics with seven-fold longer half-life. BRD4884 crosses the blood brain barrier and has been evaluated in CK-p25 mice, a mouse model of neurodegeneration. It acts by enhancing the learning and memory processes. Synonyms: BRD-4884; BRD 4884. Grades: ≥98%. CAS No. 1404559-91-6. Molecular formula: C18H19FN2O2. Mole weight: 314.4. | |
| BRD4 degrader-3 | BRD4 degrader-3 is a potent bromodomain BRD4 degrader extracted from patent WO2020055976A1, example 1a, has IC 50 s of 15.5 and 12.3 nM for BRD4-BD1 and BRD4-BD2, respectively [1]. PROTAC BRD4 Degrader-7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413382-30-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136857. | |
| BRD4-IN-4 | BRD4-IN-4 (Compound 1) is a BRD4 inhibitor ( IC 50 =6.83 μM). BRD4-IN-4 selectively inhibits MV4-11 cell line proliferation and arrests cell at G1 phase. BRD4-IN-4 can be used for research of MLL leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304685-40-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153751. | |
| BRD4 ligand 6 TFA | BRD4 ligand 6 TFA is the TFA salt form of BRD4 ligand 6 (HY-161651). BRD4 ligand 6 TFA is a BRD4 ligand and can be used for synthesis of BRD4 PROTACs, such as PROTAC BRD4 Degrader-26 (HY-161650) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763548-61-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161651A. | |
| BRD6688 | BRD6688 is an HDAC inhibitor with IC50 values of 21 nM, 100 nM, and 11.48 μM for HDAC1, 2, and 3, respectively. It possesses preferential binding kinetics with six-fold extended half-life on HDAC2 compared to HDAC1. It crosses the blood brain barrier and has been shown to rescue the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model of neurodegeneration. Synonyms: BRD-6688; BRD 6688. Grades: ≥98%. CAS No. 1404562-17-9. Molecular formula: C16H18N4O. Mole weight: 282.3. | |
| BRD 6989 | BRD 6989 is a small molecule inhibitor with high selectivity for CDK8 over CDK19. It is an analog of the natural product cortistatin A (dCA), which inhibits CDK8 and upregulates IL-10. BRD 6989 selectively binds a complex of CDK8 with an IC50 of 200 nM. It also inhibits IFNγ-induced phosphorylation of STAT1 at Ser 727 site in BMDCs. It may be useful for inflammatory disorders. Synonyms: 2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile; BRD-6989; BRD6989. Grades: ≥98%. CAS No. 642008-81-9. Molecular formula: C16H16N4. Mole weight: 264.33. | |
| BRD7116 | BRD7116 is an inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM) but does not affect normal hematopoietic stem cells or AML cells. Synonyms: BRD-7116; 2, 2, 3, 3-tetramethyl-N- [4- [4- [ (2, 2, 3, 3-tetramethylcyclopropanecarbonyl) amino] phenyl] sulfonylphenyl] cyclopropane-1-carboxamide. Grades: >98%. CAS No. 329059-55-4. Molecular formula: C28H36N2O4S. Mole weight: 496.66. | |
| BRD 7389 | BRD 7389 is a ribosomal S6 kinase (RSK) inhibitor (IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2, respectively). It upregulates insulin expression in mouse αTC1 pancreatic α cells. Synonyms: BRD7389; BRD-7389; BRD 7389; BAS 05532738; BAS05532738; BAS-05532738; 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione. Grades: ≥97% by HPLC. CAS No. 376382-11-5. Molecular formula: C24H18N2O2. Mole weight: 366.41. | |
| BRD 7389 | BRD 7389. Group: Biochemicals. Grades: Purified. CAS No. 376382-11-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BRD73954 | BRD73954 ia a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively. Synonyms: BRD73954; BRD-73954; BRD 73954. Grades: >98%. CAS No. 1440209-96-0. Molecular formula: C16H16N2O3. Mole weight: 284.31. | |
| BRD7552 | BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. Synonyms: BRD-7552; BRD 7552; BRD7552. Grades: 95%. CAS No. 1137359-47-7. Molecular formula: C33H33N3O15. Mole weight: 711.63. | |
| BRD 7552 | PDX1 transcription factor inducer; up regulates PDX1 expression in both primary human islets and ductal cells. Induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. Increases insulin expression in PANC-1 cells, primary human islets and human duct-derived cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 1137359-47-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| BRD9539 | BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2) with an IC50 value of 6.3 μM. It is selective for G9a and PRC2 over SU39H1 and NDMT1 up to a concentration of 40 μM. BRD9539 is a more potent biochemical inhibitor than its methyl-ester analogue BRD4770, with 20% remaining G9a activity compared to 45% of BRD4770 at screening concentration. Synonyms: BRD-9539; BRD 9539. Grades: ≥98%. CAS No. 1374601-41-8. Molecular formula: C24H21N3O3. Mole weight: 399.4. | |
| BRD 9757 | BRD9757 is a potent and selective histone deacetylases 6 (HDAC6) inhibitor with IC50 of 30 nM. It displays selectivity for HDAC6 over Class I HDACS (>20-fold) and Class II HDACs (>400-fold). Synonyms: N-Hydroxy-1-cyclopentene-1-carboxamide; BRD9757; BRD-9757. Grades: ≥98%. CAS No. 1423058-85-8. Molecular formula: C6H9NO2. Mole weight: 127.14. | |
| BRD 9876 | BRD 9876 is an ATP non-competitive kinesin Eg5 inhibitor. It selectively inhibits microtubule-bound Eg5 leading to an arrest in G2/M phase. Synonyms: BRD9876; BRD-9876; BRD 9876; 6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile; 6-Tert-Butyl-2,3-naphthalenedicarbonitrile. Grades: ≥99% by HPLC. CAS No. 32703-82-5. Molecular formula: C16H14N2. Mole weight: 234.3. | |
| BRD 9876 | BRD 9876. Group: Biochemicals. Grades: Purified. CAS No. 32703-82-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Breathable Membrane | Breathable Membrane. Group: Polymers. | |
| Brecanavir | Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Uses: Hiv-1 protease inhibitor. Synonyms: Brecanavir; UNII-E367I8C7FI; CHEMBL206031; GW-0385; GW-640385; GW-640385X; VX-385; GW0385; GW640385; GW640385X; VX385; GW 0385; GW 640385; GW 640385X; VX 385; [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Grades: ≥98%. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82. | |
| Brecanavir | Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Brecanavir is by a substantial margin the most potent and broadly active antiviral agent among the PIs tested in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Brecanavir; GW-0385; GW-0385; GW0385; GW-640385; GW 640385; GW640385; GW-640385X; VX-385; VX 385; VX385. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82. Purity:>98%. IUPACName: [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Canonical SMILES: Cc1nc(cs1)COc2ccc(cc2)C[C@@H]([C@@H](CN(CC(C)C)S(=O)(=O)c3ccc4c(c3)OCO4)O)NC(=O)O[C@H]5CO[C@@H]6[C@H]5CCO6. Product ID: ACM313682085-1. Alfa Chemistry ISO 9001 | |
| Brecanavir | Brecanavir (GW640385) is a novel, potent HIV protease inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW640385. CAS No. 313682-08-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121240. | |
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