A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An impurity of Bortezomib. Bortezomib is a proteasome inhibitor primarily used in the treatment of multiple myeloma (MM) and mantle cell lymphoma (MCL). Synonyms: (R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic acid; Bortezomib Related Compound A. Grade: ≥95%. Molecular formula: C10H16BN3O3. Mole weight: 237.07.
Bortezomib Impurity 9
Bortezomib Impurity 9 is an impurity of Bortezomib and a tripeptide boronic acid proteasome inhibitor used as an antitumor agent. Synonyms: N-(2-Pyrazinylcarbonyl)-L-phenylalanyl-N-[(1R)-1-borono-3-methylbutyl]-L-phenylalaninamide ; ((R)-3-Methyl-1-((S)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic Acid. Grade: > 95%. CAS No. 1194235-41-0. Molecular formula: C28H34BN5O5. Mole weight: 531.42.
Bortezomib Impurity B
Bortezomib Impurity B is used for the synthesis of Bortezomib. Synonyms: N-(2-pyrazinylcarbonyl)-L-phenylalanine; 3-Phenyl-2-[(pyrazine-2-carbonyl)amino]propionic Acid; (S)-3-Phenyl-2-(pyrazine-2-carbonylamino)propanoic Acid. Grade: 98% by HNMR. CAS No. 114457-94-2. Molecular formula: C14H13N3O3. Mole weight: 271.28.
Bortezomib Impurity F
Bortezomib Impurity F is used for the synthesis of Bortezomib. Synonyms: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester; N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester; N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester. Grade: > 95%. CAS No. 73058-37-4. Molecular formula: C15H15N3O3. Mole weight: 285.31.
Bortezomib Impurity G
Bortezomib Impurity G is an impurity of the acclaimed drug Bortezomib, a drug tailored towards the affliction of multiple myeloma. Synonyms: (S)-Hydroxy Des(boric Acid) Bortezomib; N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide. Grade: > 95%. CAS No. 289472-81-7. Molecular formula: C19H24N4O3. Mole weight: 356.43.
Bortezomib Impurity G
Bortezomib Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((S)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.24. Catalog: APB1132709148.
Bortezomib Impurity H
Bortezomib Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ((R)-3-methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.24. Catalog: APB1132709159.
Bortezomib Impurity H
Bortezomib Impurity H is an impurity of Bortezomib, a therapeutic agent for treating multiple myeloma and mantle cell lymphoma. Synonyms: (S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide. Grade: > 95%. CAS No. 1446194-56-4. Molecular formula: C19H24N4O2. Mole weight: 340.43.
Bortezomib Impurity (R,R-Isomer)
Bortezomib Impurity (R,R-Isomer) is a diastereomer of Bortezomib. Synonyms: (1R,2R)-Bortezomib; B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid. Grade: 98% by HPLC. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.25.
Bortezomib Impurity (R,S-Isomer)
Bortezomib Impurity (R,S-Isomer) is a diastereomer of Bortezomib. Synonyms: (1S,2R)-Bortezomib; B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride. Grade: > 95%. CAS No. 1132709-16-0. Molecular formula: C19H25BN4O4. Mole weight: 384.25.
Bortezomib Liposome (PEGylated)
Bortezomib (BTZ) is a proteasome inhibitor used to treat various malignancies, including lung cancer, prostate cancer, colorectal cancer, breast cancer, etc. This product is a pre-formulated liposome encapsulating Bortezomib. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
Bortezomib Pinanediol Ester
Bortezomib-pinanediol is a prodrug of Bortezomib and a proteasome inhibitor. Synonyms: N-((S)-1-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate; Bortezomib Pinanediol Impurity. Grade: 97+%. CAS No. 205393-22-2. Molecular formula: C29H39BN4O4. Mole weight: 518.46.
Bortezomib USP Impurity G
Bortezomib USP Impurity G is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Synonyms: (1S,2S)-Bortezomib; ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. Grade: 95%. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.243.
Bortezomib USP Related Compoud B
Bortezomib USP Related Compoud B is an impurity of the acclaimed drug Bortezomib, which is a drug tailored towards the affliction of multiple myeloma. Synonyms: Bortezomib Amide Impurity; N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grade: 98% by HPLC. CAS No. 289472-80-6. Molecular formula: C14H14N4O2. Mole weight: 270.29.
Borussertib
Borussertib is a covalent-allosteric Akt inhibitor with IC50 of 0.8 nM. Borussertib displays antitumor activity in combination with the MEK inhibitor trametinib in patient-derived xenograft models and provides a starting point for further pharmacokinetic/dynamic optimization. CAS No. 1800070-77-2. Molecular formula: C36H32N6O3. Mole weight: 596.68.
Borussertib
Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1800070-77-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-122913.
BOS172722
BOS172722 is a potent and selective monopolar spindle 1 (MPS1) checkpoint inhibitor with IC50 of 11 nM. Synonyms: BOS-172722; BOS 172722; N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine. CAS No. 1578245-44-9. Molecular formula: C24H30N8O. Mole weight: 446.55.
BOS-318
BOS-318 is a potent, slowly dissociating, highly selective, and cell-permeable furin inhibitor with IC50 value of 1.9 nM. BOS-318 protects ENaC from subsequent activation by neutrophil elastase. BOS-318 can be used for the rsearch for CF lung disease[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387633-15-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147140.
Boscalid
Boscalid is an anti-fungal agent. Boscalid is a succinate dehydrogenase (SDH) inhibitor [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 188425-85-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-119976.
Boscalid
analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. Alternative Names: 3-Pyridinecarboxamide, 2-chloro-N-(4'-chloro[1,1'-biphenyl]-2-yl)-, Nicobifen, Endura, Filan, F 510, 2-Chloro-N-(4'-chlorobiphenyl-2-yl)nicotinamide, Cantus, BAS 510F, Boscalid, Emerald, Emerald (fungicide).
Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Synonyms: Ro 47-0203. Grade: >98%. CAS No. 147536-97-8. Molecular formula: C27H29N5O6S. Mole weight: 551.61.
Bosentan
A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N- [6- (2-hydroxyethoxy) -5- (o-methoxyphenoxy) -2- (2-pyrimidinyl) -4-pyrimidinyl] benzenesulfonamide; Actelion; Ro 47-0203; Ro 47-0203/039; Tracleer. Grades: Highly Purified. CAS No. 147536-97-8. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C27H29N5O6S, Molecular Weight: 551.62. US Biological Life Sciences.
Worldwide
Bosentan
Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 147536-97-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013.
Bosentan
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C27H29N5O6S. CAS No. 147536-97-8. Prepack ID 54399509-1g. Molecular Weight 551.61. See USA prepack pricing.
Bosentan
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Bosentan-[13C2,d4]
Bosentan-[13C2,d4] is the labeled analogue of Bosentan, a mixed endothelin receptor antagonist used as a vasodilator. Synonyms: 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy-1,2-13C2-1,1,2,2-d4)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide; 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy-13C2,d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N-[6-(2-hydroxyethoxy-13C2,d4)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide; Actelion-13C2,d4; Ro 47-0203-13C2,d4; Ro 47-0203/039-13C2,d4; Tracleer-13C2,d4; Bosentan-13C2,d4. Grade: >95%. Molecular formula: C25[13C]2H25D4N5O6S. Mole weight: 557.62.
Bosentan-[d4]
Bosentan-[d4] is the labelled analogue of Bosentan. Bosentan is an endothelin receptor antagonist indicated for pulmonary artery hypertension (PAH). Synonyms: Bosentan D4; 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N-[6-(2-hydroxyethoxy-d4)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide; Actelion-d4; Ro 47-0203-d4; Tracleer-d4. Grade: ≥96% by HPLC; ≥99% atom D. CAS No. 1065472-77-6. Molecular formula: C27H25D4N5O6S. Mole weight: 555.65.
A labeled mixed endothelin receptor antagonist. Used as a vasodilator. Group: Biochemicals. Alternative Names: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Bosentan hydrate
Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ET A and ET B receptors with K i of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 157212-55-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013A.
Bosentan hydrate
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H29N5O6S. H2O. CAS No. 157212-55-0. Prepack ID 20114584-1g. Molecular Weight 569.63. See USA prepack pricing.
Bosentan hydrate
Bosentan inhibits the presser response to big ET-1 both after i.v. and oral administration, with a long duration of action and no intrinsic agonist activity. Synonyms: Ro 47-0203; Ro 470203; Ro470203; Ro-470203. Grade: >98%. CAS No. 157212-55-0. Molecular formula: C27H29N5O6S.H2O. Mole weight: 569.63.
Bosentan Hydrate
Bosentan Hydrate. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide Hydrate (1:1). Grades: Highly Purified. CAS No. 157212-55-0. Pack Sizes: 25mg. Molecular Formula: C27H31N5O7S, Molecular Weight: 569.63. US Biological Life Sciences.
Bosentan impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1065472-77-6. Molecular formula: C27H25D4N5O6S. Mole weight: 555.64. Catalog: APB1065472776.
Bosentan Impurity 1
Bosentan Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.17. Catalog: APB150728135.
Bosentan Impurity 3
Bosentan Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butyl)-N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.01. Catalog: APB150727063.
Bosentan Impurity D
Bosentan Impurity D is an impurity of Bosentan. Synonyms: O-Deshydroxyethyl Bosentan; N-[1,6-Dihydro-5-(2-methoxyphenoxy)-6-oxo[2,2'-bipyrimidin]-4-yl]-4-(1,1-dimethylethyl)benzenesulfonamide; 4-tert-Butyl-N-[6-hydroxy-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide. Grade: > 95%. CAS No. 174227-14-6. Molecular formula: C25H25N5O5S. Mole weight: 507.57.
Bosentan Related Compound 1
Bosentan Related Compound 1 is an exquisite biomedical concoction used in the research of the complex ailment known as pulmonary arterial hypertension. Functioning as a highly discerning antagonist of the endothelin receptor, it proficiently curbs the constriction. Synonyms: 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine; Bosentan Related Compound D; 4,6-Dichloro-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)pyrimidine; Bosentan Related Compound D USP. Grade: > 95%. CAS No. 150728-13-5. Molecular formula: C15H10Cl2N4O2. Mole weight: 349.18.
Bosentan Related Compound 2
Bosentan Related Compound 2 is an intermediate as well as a degradation impurity of the endothelin receptor antagonist Bosentan. Synonyms: 4-tert-Butylbenzenesulfonamide; 4-(1,1-Dimethylethyl)benzenesulfonamide; p-tert-butyl-Benzenesulfonamide; NSC 9911. Grade: > 95%. CAS No. 6292-59-7. Molecular formula: C10H15NO2S. Mole weight: 213.30.
Bosentan Related Compound 3
Bosentan Related Compound 3 is an intermediate of Bosentan. Synonyms: N-[6-Chloro-5-(2-methoxyphenoxy)-(2,2-bipyrimidine)4-4-yl]-(1,1-dimethylethyl)-benzenesulfonamide; 4-tert-Butyl-N-[6-chloro-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzeneSulfonamide. Grade: > 95%. CAS No. 150727-06-3. Molecular formula: C25H24ClN5O4S. Mole weight: 526.02.
Bosentan Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Bosentan Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Bosentan Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Bosentan Related Compound C
Bosentan Related Compound C is an impurity of Bosentan. Synonyms: N,N'-[1,2-Ethanediylbis[oxy[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-6,4-diyl]]]bis[4-(1,1-dimethylethyl)-benzenesulfonamide; 1,2-Bis({6-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl}oxy)ethane; Bosentan dimer. Grade: > 95%. CAS No. 1097263-60-9. Molecular formula: C52H52N10O10S2. Mole weight: 1041.18.
Bosentan Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Bosentan Related Compound E
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Boserolimab
Boserolimab (MK-5890) is a humanized agonist monoclonal antibody that binds to CD27 to provide a costimulatory signal that enhances T-cell - mediated responses [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MK-5890. CAS No. 2444297-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990018.
Boss Fittings
Boss Fittings. Group: Polymers.
Bostrycin
Bostrycin is a scallion antibiotic produced by Bostrychonema alpestre. It has anti-gram-positive bacteria, negative bacteria, mycobacteria, Candida albicans and other fungi activity, and has inhibitory effect on S-189 and Friend leukemia cells. Synonyms: Rhodosporin. Grade: ≥95%. CAS No. 21879-81-2. Molecular formula: C16H16O8. Mole weight: 336.29.
Bosutinib
Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC 50 of 1.2 nM and 1 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKI-606. CAS No. 380843-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10158.
Bosutinib
A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; SKI 606. Grades: Highly Purified. CAS No. 380843-75-4. Pack Sizes: 5mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
Bosutinib
Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, respectively. Synonyms: 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosulif; KIN 001-160; SK 606; SKI 606; SKI606; SK-I606. Grade: >98%. CAS No. 380843-75-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.45.
A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. This is the labeled analog. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile-d8; SKI 606-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Bosutinib-[d8]
Bosutinib-[d8] is the labelled analogue of Bosutinib. Bosutinib is a tyrosine kinase inhibitor promisingly for cancer therapy. Synonyms: Bosutinib D8; SKI606-d8; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile-d8. Grade: >95%. CAS No. 2733145-45-2. Molecular formula: C26H21D8Cl2N5O3. Mole weight: 538.49.
Bosutinib hydrate
Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC 50 of 1.2 nM and 1 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKI-606 hydrate. CAS No. 918639-08-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10158A.
Bosutinib Isomer
Bosutinib Isomer is an isomer of Bosutinib. Synonyms: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile; Bosutinib isomer 4; PF-06651481; PF-06651481-00. Grade: > 95%. CAS No. 1391063-17-4. Molecular formula: C26H29Cl2N5O3. Mole weight: 530.46.
Bosutinib Isomer Methanoate
Bosutinib Isomer is the 3,5-dichloro-4-methoxy isomer of Bosutinib. It has been reported that this compound has been offered incorrectly as Bosutinib (B676095) C&E News 90 (21) 2012 34-35 and Levinson NM, Boxer SG (2012) Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain. PLoS ONE 7(4): e29828. doi:10. 1371/journal. pone. 0029828. Group: Biochemicals. Alternative Names: 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Methanoate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Bosutinib methanoate
Bosutinib methanoate. Group: Biochemicals. Alternative Names: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile methanoate; SKI 606 methanoate. Grades: Highly Purified. CAS No. 918639-10-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C27H33Cl2N5O4. US Biological Life Sciences.
Worldwide
Bosutinib monohydrate
Bosutinib hydrate is a Src/Abl inhibitor used in the treatment of chronic myeloid leukemia (CML), a type of cancer that affects the blood and bone marrow. Bosutinib is a tyrosine kinase inhibitor that works by blocking the activity of BCR-ABL, a protein that promotes the growth of abnormal leukemia cells in patients with CML. BCR-ABL is formed as a result of a genetic abnormality known as the Philadelphia chromosome. It is indicated for the treatment of adults with newly diagnosed chronic phase CML as well as CML that is resistant or intolerant to prior therapy, including imatinib. Synonyms: Bosutinib hydrate; 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-, hydrate (1:1); 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile hydrate; Bosulif hydrate; KIN 001-160 hydrate; SK 606 hydrate; SKI 606 hydrate. Grade: 98%. CAS No. 918639-08-4. Molecular formula: C26H29Cl2N5O3.H2O. Mole weight: 548.46.
Bosutinib N-oxide
Bosutinib N-oxide is an impurity of Bosutinib, a BCR-ABL and src tyrosine kinase inhibitor used as an antineoplastic agent. Synonyms: 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-4-oxido-1-piperazinyl)propoxy]-. Grade: 95%. CAS No. 2468737-96-2. Molecular formula: C26H29Cl2N5O4. Mole weight: 546.4.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Boswellia Serrata Extract
Boswellia Serrata Extract. Group: Others. Purity: 10:1, 20:1, Boswellic acid40% 50% 65%. Appearance: Brown powder. Source: Boswellia is a genus of trees in the order Sapindales, known for their fragrant resin which has many pharmacological uses, particularly as anti-inflammatories. Boswellia Serrata Extract. Cat No: EXTC-175.
Boswellic acid
α-Boswellic acid, a pentacyclic triterpene molecule, is isolated from the herbs of Boswellia carterii Birdw. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: (18β)-3α-Hydroxygermanica-12-ene-24-oic acid; (4R)-3α-Hydroxyolean-12-en-24-oic acid. Grade: 98%. CAS No. 471-66-9. Molecular formula: C30H48O3. Mole weight: 456.7.
Botensilimab (AGEN 1181), a human anti- cytotoxic T-lymphocyte antigen 4 (CTLA-4) monoclonal antibody, is an innate and adaptive immune activator. Botensilimab can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AGEN 1181. CAS No. 2408310-37-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99484.
bothrolysin
A 22.5 kDa endopeptidase from the venom of the jararaca snake (Bothrops jararaca), insensitive to phosphoramidon at 0.5 mM. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Bothrops metalloendopeptidase J; J protease. Enzyme Commission Number: EC 3.4.24.50. CAS No. 443890-65-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4332; bothrolysin; EC 3.4.24.50; 443890-65-1; Bothrops metalloendopeptidase J; J protease. Cat No: EXWM-4332.