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The zymogen factor IX is a single chain vitamin K-dependent glycoprotein which is synthesized in the liver. The domain structure of factor IX is similar to that of the other vitamin K dependent coagulation factors. The NH2-terminal region contains 12 γ-carboxyglutamic acid (gla) residues which facilitate the calcium dependent binding of factor IX to negatively charged phospholipid surfaces. Two domains which are homologous to epidermal growth factor (EGF) span the region between the NH2-terminal gla domain and the activation peptide (Ala-146 to Arg-180).Factor IX is activated by either factor XIa or the factor VIIa/tissue factor/phospholipid complex. Cleavage at site A (see fig. activates factor X to factor Xa.Human factor IX is prepared from fresh frozen plasma by a combination of conventional procedures and immunoaffinity chromatography. Bovine factor IX is prepared from fresh citrated bovine plasma by a modification of the method described by Fujikawa et al. The purified proteins are supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a factor IX clotting assay. Group: Zymogens. CAS No. 9001-28-9. Purity: >95% by SDS-PAGE. Factor IX. Mole weight: 55400. Stability: 12 months. Storage: -20°C. Source: Bovine. Bovine factor IX; Factor IX. Pack: 100 ug. Cat No: CZY-003.
Bovine Factor X
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a disulfide bond. Prior to secretion into plasma, post-translational modifications produce 11 gamma-carboxyglutamic acid (gla) residues and a single b-hydroxyaspartic acid residue, which are located within the NH2-terminal light chain. The light chain also contains two epidermal growth factor (EGF) homology domains. The COOH-terminal heavy chain of factor X contains most of the carbohydrate moieties, as well as the latent serine protease domain. The activation of factor X is catalyzed by either the intrinsic factor Xase complex (factor IXa, fa.y of the prothrombinase complex. The first EGF homology domain contains a Ca2+ binding site which acts as a hinge to fold the EGF and GLA domains towards each other. This region of the molecule is involved in the recognition of cellular binding domains.Human factor X is isolated from fresh frozen human plasma by a combination of conventional techniques and immunoaffinity chromatography. In addition to the standard human factor X preparation, Gla-domainless human factor X is also available. Bovine factor X is isolated from fresh bovine plasma using a modification of the procedure reported by Bajaj et al. The purified zymogen is supplied in 50% (vol/vol) glycerol/H2O and should be store.
Bovine fibrillar collagen solution
Bovine fibrillar collagen solution. Group: Natural polymers and biopolymers. CAS No. 9007-34-5.
Bovine Freeze Dried Adrenal Substance Powder
Bovine Freeze Dried Adrenal Substance Powder.
CA, FL & NJ
Bovine Freeze Dried Bone Marrow Powder
Bovine Freeze Dried Bone Marrow Powder.
CA, FL & NJ
Bovine glu-Plasminogen
Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4 uM. The plasminogen molecule contains 790 amino acids, 24 disulfide bridges, no free sulfhydryls and 5 regions of internal sequence homology, known as kringles, between Lys77 and Arg560. These five triple-looped, three disulfide bridged, kringle regions are homologous to the kringle domains in t-PA, u-PA and prothrombin. Plasminogen contains one high affinity (Kd=9x10-6M) and four low affinity (Kd=5x10-3M) lysine binding sites. The high affinity binding site resides within the first kringle region of plasminogen. The interaction of p.hich remain covalently associated by a disulfide bond.Native glu-plasminogen is prepared from fresh frozen human plasma by a modification of the procedure of Castellino, utilizing gel filtration and affinity chromatography. The two carbohydrate variants of glu-plasminogen (CHOI and CHOII) are isolated by gradient elution from lysine-Sepharose using the lysine analog, e-aminocaproic acid. The plasminogen is supplied in 50% (vol/vol) glycerol/H2O for storage at -20°C. Purity is determined by SDS-PAGE analysis. Group: Zymogens. Purity: >95% by SDS-PAGE. Plasminogen. Stability: 12 months. Storage: -20°C. Source: Bovine. Bovine glu-Plasminogen; Plasminogen. Pack: 1 mg. Cat No: CZY-015.
Bovine Heme Iron Polypeptide (HIP) 2% Iron
Bovine Heme Iron Polypeptide (HIP) 2% Iron.
CA, FL & NJ
Bovine Hemoglobin Powder
Bovine Hemoglobin Powder.
CA, FL & NJ
Bovine Liver Defatted Powder (40 Mesh)
Bovine Liver Defatted Powder (40 Mesh).
CA, FL & NJ
Bovine Lung Powder
Bovine Lung Powder.
CA, FL & NJ
Bovine Lymphatic Substance Powder
Bovine Lymphatic Substance Powder.
CA, FL & NJ
Bovine Lymph Freeze Dried Powder
Bovine Lymph Freeze Dried Powder.
CA, FL & NJ
Bovine Neutrophil beta-defensin 5
Neutrophil beta-defensin 5 is an antimicrobial peptide found in Bos taurus (Bovine), and has antibacterial activity. Synonyms: BNBD 5; Neutrophil beta-defensin 5. Grade: >98%.
Purified from freshly collected bovine plasma. The protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. No Plasmin activity is detected using chromogenic substrate S-2251. Plasminogen is activated to the serine protease plasmin via urokinase, streptokinase or tissue plasminogen activator. Group: Zymogens. Purity: >94% by SDS-PAGE. Plasminogen. Mole weight: 90,000-94,000. Stability: 30 months. Storage: 2-8°C. Source: Bovine. Bovine Plasminogen; Plasminogen. Pack: 1mg. Cat No: CZY-030.
Bovine Protein C
The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide linked heterodimer, by removal of a dipeptide (Lys-146 and Arg-147) from the precursor molecule. Trace quantities of the single chain form have been observed in plasma. The light chain, which is responsible for the calcium dependent binding of protein C to phospholipid vesicles, contains 11 γ-carboxyglutamic acid (gla) residues, 1 b-hydroxyaspartic acid residue, and 2 epidermal growth factor (EGF) homology domains. The serine protease catalytic triad is located in the heavy chain. Human protein C is susceptible to proteolytic cleavag.g the proteolytic inactivation of factors Va and VIIIa. APC also contributes to the fibrinolytic response by complex formation with plasminogen activator inhibitors.Bovine protein C is prepared from fresh citrated bovine plasma by a modification of the Walker procedure, as described by Haley et al. Human protein C is prepared from fresh frozen citrated human plasma using a combination of immunoaffinity chromatography, and conventional techniques. Protein C is provided in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a chromogenic substrate based assay. Group: Zymogens. Purity: >95% by SDS-PAGE. Prote.
Bovine Prothrombin
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature p.Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20.
Bovine Serum Albumin
100g Pack Size. Group: Amino Acids, Analytical Reagents, Biochemicals. Formula: N/A. CAS No. 9048-46-8. Prepack ID 22574477-100g. See USA prepack pricing.
Bovine Serum Albumin
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Albumin bovine serum; BSA. CAS No. 9048-46-8. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0842.
Bovine Serum Albumin
Bovine Serum Albumin. CAS No. 9048-46-8. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Bovine Serum Albumin (Low Endotoxin,Fatty acid free)
Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) is a 583 amino acid globular protein and oligonucleotide binding protein composed of three homologous full ? domains. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) blocks the overall binding of oligonucleotides to cells. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) regulates the development of hamster embryos and induces arthritis[1][2][3][4]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Albumin bovine serum (Low Endotoxin,Fatty acid free); BSA (Low Endotoxin,Fatty acid free). CAS No. 9048-46-8. Pack Sizes: 1 g; 5 g. Product ID: HY-D0842A.
Bovine Serum Albumin solution
35% in DPBS, sterile-filtered, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Bovine Serum Protein Concentrate Powder
Bovine Serum Protein Concentrate Powder.
CA, FL & NJ
Bovine Spleen Substance Powder
Bovine Spleen Substance Powder.
CA, FL & NJ
Bovine Superoxide dismutase-polyethylene glycol
Superoxide dismutases (SOD) are enzymes that alternately catalyze the dismutation (or partitioning) of the superoxide (O2-) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2-). Group: Enzymes. Synonyms: PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. SOD. Activity: 11,000 units/mg SOD before conjugation; SOD/PEG ratio: 10-20 PEG with each SOD enzyme. Appearance: Off-white. Storage: Store at -20°C. Form: Lyophilized powder. Source: Bovine Kidney. Species: Bovine. PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. Cat No: NATE-0682.
Bovine tendon powder
Bovine tendon powder. Group: Natural polymers and biopolymers. CAS No. 9007-34-5.
Bovine Thymus Powder Thymomodulin 99% HPLC
Bovine Thymus Powder Thymomodulin 99% HPLC.
CA, FL & NJ
Bovine Thymus Substance Powder
Bovine Thymus Substance Powder.
CA, FL & NJ
Bovine Thyroid Freeze Dried Powder
Bovine Thyroid Freeze Dried Powder.
CA, FL & NJ
Bovine Thyroid Thyroxin Free Powder
Bovine Thyroid Thyroxin Free Powder.
CA, FL & NJ
Bovinocidin
Bovinocidin is a fatty acid derivative produced by Streptomyces sp., Aspergillus avenaceus, Asp. flavust, Asp. oryzae and Penicillum atrovenetum. The minimum inhibitory concentration for BCG tuberculosis (BCG) is 50-100 ?/mL. Uses: Antihypertensive agents. Synonyms: Hiptagenic acid. Grade: >98%. CAS No. 504-88-1. Molecular formula: C3H5NO4. Mole weight: 119.08.
Box5
Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma [1]. Uses: Scientific research. Group: Peptides. CAS No. 1206604-29-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123071.
Boxazomycin A
Boxazomycin A is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. Synonyms: 4-Benzoxazolecarboxamide, 5-hydroxy-2-(5-hydroxy-2-(hydroxymethyl)-4-pyrimidinyl)-7-methyl-; (2Z)-5-hydroxy-2-[2-(hydroxymethyl)-5-oxopyrimidin-4-ylidene]-7-methyl-3H-1,3-benzoxazole-4-carboxamide. CAS No. 107021-64-7. Molecular formula: C14H12N4O5. Mole weight: 316.27.
Boxazomycin B
Boxazomycin B is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. CAS No. 107021-65-8. Molecular formula: C14H12N4O4. Mole weight: 300.27.
Boxazomycin C
Boxazomycin C is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. CAS No. 107021-66-9. Molecular formula: C14H12N4O4. Mole weight: 300.27.
BP-1-102
BP-1-102 is a potent and selective STAT3 inhibitor. BP-1-102 inhibits the expression of genes including c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and Krüppel-like factor 8, which is related to the STAT3-mediated breast tumor growth and migration. Synonyms: 4-(N-(4-cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid. Grade: >98%. CAS No. 1334493-07-0. Molecular formula: C29H27F5N2O6S. Mole weight: 626.595.
BP-1-102
BP-1-102 is an orally available, small-molecule inhibitor of transcription factor Stat3, with an IC50 of 6.8 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334493-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-100493.
BP4mPy
BP4mPy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 33'55'-Tetra[(m-pyridyl)-phen-3-yl]biphenyl. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1009033-94-6. Molecular formula: C56H38N4. Mole weight: 766.93 g/mol. Product ID: ACM1009033946. Alfa Chemistry ISO 9001:2015 Certified.
BP 554
BP 554 is a selective 5-HT1A agonist. Synonyms: Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-; 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine; BP554; BP-554; LASSBio 670; 1-(3-(3,4-Methylenedioxyphenoxy)propyl)-4-phenylpiperzine. Grade: ≥95%. CAS No. 82900-57-0. Molecular formula: C20H24N2O3. Mole weight: 340.42.
Bp 554 maleate
Bp 554 maleate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tocris-0556, Biomol-NT_000106, BPBio1_001399, BP 554, BP-554, CID134117, NCGC00024650-01, NCGC00024650-02, L003497, BRD-K45479396-001-01-8, 1-(3-(3,4-Methylenedioxyphenoxy)propyl)-4-phenylpiperzine, 1-[3-(1,3-Benzodioxol-5-yloxy)propyl]-4-phenylpiperazine, 1-[3-3,4-Methylenedioxyphenoxy;propyl]-4-phenylpiperazine, Piperazine, 1-(3-(1,3-benzodioxol-5-yloxy)propyl)-4-phenyl-, 82900-57-0. Product Category: Heterocyclic Organic Compound. CAS No. 82900-57-0. Molecular formula: C20H24N2O3.C4H4O4. Mole weight: 456.49. Purity: >99 %. IUPACName: 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenylpiperazine. Canonical SMILES: C1CN(CCN1CCCOC2=CC3=C(C=C2)OCO3)C4=CC=CC=C4. Density: 1.188g/cm³. Product ID: ACM82900570. Alfa Chemistry ISO 9001:2015 Certified.
BP 554 maleate
BP 554 maleate is a selective 5-HT1A agonist. Synonyms: Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-, (2Z)-2-butenedioate (1:1); 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine maleate; 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenylpiperazine maleate. Grade: ≥99% by HPLC. CAS No. 1221401-95-1. Molecular formula: C20H24N2O3.C4H4O4. Mole weight: 456.48.
BP 554 maleate
BP 554 maleate. Group: Biochemicals. Grades: Purified. CAS No. 1221401-95-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
BP 897, a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist, has a high affinity for the dopamine D3 receptor (Ki = 0.92 nM) and a 70 times lower affinity for the D2 receptor (Ki = 61 nM). It shows selective inhibition of cocaine-seeking behavior. Uses: Dopamine agonists. Synonyms: 2-Naphthalenecarboxamide, N-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-; BP-897; BP897; N-[4-(4-(2-Methoxyphenyl)piperazinyl)butyl]-2-naphthamide; N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide. CAS No. 192384-87-5. Molecular formula: C26H31N3O2. Mole weight: 417.54.
BP 897 hydrochloride
BP 897 hydrochloride, a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist, has a high affinity for the dopamine D3 receptor (Ki = 0.92 nM) and a 70 times lower affinity for the D2 receptor (Ki = 61 nM). It shows selective inhibition of cocaine-seeking behavior. Uses: Dopamine agonists. Synonyms: 2-Naphthalenecarboxamide, N-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-, monohydrochloride; N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide hydrochloride; N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-2-naphthamide hydrochloride (1:1). Grade: ≥95%. CAS No. 314776-92-6. Molecular formula: C26H32ClN3O2. Mole weight: 454.00.
BPAPF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9-Bis[4-(N,N-bis-biphenyl-4-yl-amino)phenyl]-9H-fluorene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 174141-92-5. Molecular formula: C73H52N2. Mole weight: 957.21 g/mol. Product ID: ACM174141925. Alfa Chemistry ISO 9001:2015 Certified. Categories: BPAP machine.
BPBPA
BPBPA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4,N4,N4',N4'-Tetra[(1,1'-biphenyl)-4-yl]-(1,1'-biphenyl)-4,4'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 164724-35-0. Molecular formula: C60H44N2. Mole weight: 793 g/mol. Product ID: ACM164724350-3. Alfa Chemistry ISO 9001:2015 Certified. Categories: BPB Partecipazioni.
BPC 157
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 137525-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105174.
BPC 157 acetate
BPC 157 acetate is a synthetic pentadecapeptide that is beneficial for the treatment of ulcers in the stomach, intestinal damage such as fistulas and inflammatory disorders, bone and joint healing and growth rates, and organ damage. Uses: Bpc 157 acetate is a peptide inhibitor, a serine-proline peptide produced by gastric mucosal smooth muscle cells in vivo. it has attracted the interest of researchers and has shown potential in the field of drug development. the main mechanisms of action of bpc 157 acetate include promoting healing, anti-inflammatory and antioxidant activities, which make it have a wide range of application potent. Synonyms: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH.CH3CO2H; glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolyl-glycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanyl-glycyl-L-leucyl-L-valine acetic acid. Grade: ≥95%. CAS No. 216441-37-1. Molecular formula: C64H102N16O24. Mole weight: 1479.61.
BPDBA is a selective and noncompetitive betaine/GABA transporter ( BGT-1 ) inhibitor with IC 50 s of 20 μM and 35 μM against human BGT-1 and mouse GAT2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312281-74-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119591.
BPD-Ring B
BPD-Ring B is a product from the synthesis of verteporfinin. It can be used for making porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic drugs. Uses: Make porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic drugs. Synonyms: BPD-B; Benzoporpyrin Ring B derivative; 23H,25H-Benzo[b]porphine-9,13- dipropanoic acid, 19-ethenyl-1,22a-dihydro-1,2-bis(methoxycarbonyl)-8,14,18, 22a-tetramethyl-, dimethyl ester. Grade: 98%. CAS No. 143986-17-8. Molecular formula: C42H44N4O8. Mole weight: 732.83.
BPH-1358
BPH-1358 is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) with IC50s of 1.8 μM and 110 nM, respectively. It has activity against Staphylococcus aureus in vitro (MIC ~250 ng/mL). Synonyms: TS-07705; HY-118946. CAS No. 5352-53-4. Molecular formula: C32H30Cl2N6O2. Mole weight: 601.5.
BPH-1358 free base
BPH-1358 free base is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) with IC50s of 1.8 μM and 110 nM, respectively. It has activity against Staphylococcus aureus in vitro (MIC ~250 ng/mL). Synonyms: NSC 50460 free base; N,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]biphenyl-4,4'-dicarboxamide; N,N'-Bis[3-(4,5-dihydro-1H-imidazole-2-yl)phenyl]-1,1'-biphenyl-4,4'-dicarboxamide; [1,1'-Biphenyl]-4,4'-dicarboxamide, N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-; N,N'-Bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-4,4'-biphenyldicarboxamide. Grade: ≥95%. CAS No. 801985-13-7. Molecular formula: C32H28N6O2. Mole weight: 528.60.
BPH-1358 mesylate
BPH-1358 mesylate is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. BPH-1358 mesylate is active against S. aureus in vitro (MIC ~250 ng/mL). Synonyms: NSC50460 mesylate. Molecular formula: C34H36N6O8S2. Mole weight: 720.82.
BPH-652
BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections. Synonyms: BMS-187745; BPH-652; BMS 187745; BPH 652; BMS187745; BPH652; CHEMBL351151; BMS 188745 Potassium Salt; DNC009027; KB-75764; tripotassium; 4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate. Grade: 98%. CAS No. 157124-84-0. Molecular formula: C16H16K3O7PS. Mole weight: 500.63.
BPH715
BPH715 is a new generation of lipophilic bisphosphonates. It is potent in cell culture and effectively inhibited tumor cell growth and invasiveness. It is used as anticancer agents that block protein prenylation also have potent activity against Plasmodium liver stages. It has activity against a Plasmodium geranylgeranyl diphosphate synthase (GGPPS), as well as low nM activity against human farnesyl and geranylgeranyl diphosphate synthases. It is used to treat bone resorption diseases and has activity against a broad range of protists, including blood-stage Plasmodium spp. Uses: Bph715 is used as anticancer agents that block protein prenylation also have potent activity against plasmodium liver stages. it is also used to treat bone resorption diseases and has activity against a broad range of protists. Synonyms: BPH-715; BPH 715; BPH715; GTPL3196; GTPL 3196; GTPL-3196; Bisphpshonate-715. 3-(Decyloxy)-1-(2-hydrogen phosphonato-2-phosphonoethyl)pyridin-1-ium; Bisphpshonate-715; [2-(3-Decoxypyridin-1-ium-1-yl)-1-phosphonoethyl]-hydroxyphosphinate; Hydrogen (2-(3-(decyloxy)pyridin-1-ium-1-yl)-1-phosphonoethyl)phosphonate. Grade: >98%. CAS No. 1059677-23-4. Molecular formula: C17H31NO7P2. Mole weight: 423.38.
BPHA
BPHA is a potent and orally active MMP-2 , MMP-9 and MMP-14 inhibitor with IC 50 s of 12 nM, 16 nM and 17 nM, respectively. BPHA does not inhibit MMP-1, -3, and -7 (the IC 50 s are 974, >1000, and 795 nM, respectively). BPHA has antiangiogenic and antitumor effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193807-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114785.
Bphen
Bphen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 47-Diphenyl-110-phenanthroline. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1662-01-7. Molecular formula: C24H16N2. Mole weight: 332.4 g/mol. Product ID: ACM1662017-4. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4,7-Diphenyl-1,10-phenanthroline, B-Phenethylamine.
B-Phycoerythrin, activated
BioReagent, suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
BPI-3016
BPI-3016 is an analogue of human glucagon-like peptide 1 (hGLP-1) that has a long effect on type 2 diabetes mellitus. In vitro, BPI-3016 exhibited an affinity to GLP receptors and promotes cAMP production. In vivo, the half-life of BPI-3016 was 95h after single dosing in pharmacokinetic studies in diabetic cynomolgus monkey models. Uses: The treatment of type 2 diabetes. Synonyms: BPI-3016; BPI 3016; BPI3016.
BPI-9016M
BPI-9016M is a potent, orally active, and selective dual c-Met and AXL tyrosine kinases inhibitor. BPI-9016M suppresses tumor cell growth, migration and invasion of lung adenocarcinoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1528546-94-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114356.
BPI-9016M
BPI-9016M, a potent, orally active and selective dual c-Met and AXL tyrosine kinase inhibitor, inhibits lung adenocarcinoma tumor cell growth, migration and invasion. Synonyms: N-[4-(2,3-Dihydro-1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenyl]-5-(4-fluorophenyl)-4-oxo-1,4-dihydro-3-pyridinecarboxamide; 3-Pyridinecarboxamide, N-[4-[(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-1,4-dihydro-4-oxo-. Grade: ≥95%. CAS No. 1528546-94-2. Molecular formula: C25H18F2N4O3. Mole weight: 460.43.
bPiDDB
bPiDDB is a neuronal nicotinic acetylcholine receptor (AChR) antagonist with IC50s of 0.17, 0.25, 0.4, 4.8, 6.5, 8.2, 20 and 34 μM at α3β4, α1β1γδ, α3β4β3, α6β4β3, α7, α4β2, α3β2β3 and α6/3β2β3 receptors, respectively. Synonyms: Pyridinium, 1,1'-(1,12-dodecanediyl)bis[3-methyl-, bromide (1:2); Pyridinium, 1,1'-(1,12-dodecanediyl)bis[3-methyl-, dibromide; 1,1'-(1,12-Dodecanediyl)bis[3-methylpyridinium] dibromide; N,N'-Dodecylbis-Picolinium Bromide; N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide; 1,1'-(Dodecane-1,12-diyl)bis(3-methylpyridin-1-ium) bromide; BPiDDB. Grade: ≥95%. CAS No. 525596-66-1. Molecular formula: C24H38Br2N2. Mole weight: 514.38.
bPiDDB
bPiDDB is a potent nAChR antagonist. bPiDDB potently ( IC 50 =2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 525596-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107674.