A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Potent and selective endothelin receptor A (ETA) antagonist. Suppresses the ET-1-induced decrease of LPL activity. Shows protective effects in ischemic acute renal failure. Neuroprotective. Anti-hypertensive. Inhibits ET-1 receptor binding and blocks Ca2+ mobilization, cellular contraction and MAP kinase activation. Cardiovascular agent. Reduces myocardial infarct size and oxidant injury. Source:Synthetic. Group: Biochemicals. Grades: Highly Purified. CAS No. 136553-81-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C31H42N6O7 Na. US Biological Life Sciences.
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BQ-3020
BQ-3020. Group: Biochemicals. Grades: Purified. CAS No. 143113-45-5. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
BQ-3020
BQ-3020 is a potent and selective ETB endothelin receptor agonist (Ki = 0.18 and 970 nM at human ETB and ETA receptors, respectively). Synonyms: endothelin receptor antagonist; Acetyl-(Ala11·15)-Endothelin-1 (6-21). CAS No. 143113-45-5. Molecular formula: C96H140N20O25S. Mole weight: 2006.3.
BQ-788
BQ-788 is a potent and selective ETB receptor antagonist with an IC50 of 1.2 nM. Synonyms: BQ-788 free acid; D-Norleucine, N-((cis-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-; N-cis-2,6-Dimethylpiperidinocarbonyl-β-tBu-Ala-D-Trp(1-methoxycarbonyl)-D-Nle-OH. Grades: 95%. CAS No. 173326-37-9. Molecular formula: C34H51N5O7. Mole weight: 641.80.
BQ-788
BQ-788 is a potent, selective ETB receptor antagonist with IC 50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC 50 of 1300 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173326-37-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-15894A.
BQ 788 sodium salt
BQ 788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM) without significant activity on ETA receptor (IC50= 1300 nM). Uses: Antihypertensive agents. Synonyms: cis-N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine Monosodium Salt; N-[[(2R,6S)-2,6-Dimethyl-1-piperidinyl]carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; (R)-2-((R)-2-((S)-2-((2S,6R)-2,6-Dimethylpiperidine-1-carboxamido)-4,4-dimethylpentanamido)-3-(1-(methoxycarbonyl)-1H-indol-3-yl)propanamido)hexanoic Acid Sodium Salt. Grades: 95%. CAS No. 156161-89-6. Molecular formula: C34H50N5NaO7. Mole weight: 663.78.
BQ-788 sodium salt
BQ-788 sodium salt is a potent and selective ETB receptor antagonist, inhibiting ET-1 binding to ETB receptors with an IC 50 of 1.2 nM in human Girrardi heart cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 156161-89-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15894.
BQ-788 Sodium Salt
Highly selective ETB-receptor antagonist (IC50=1.2nM). BQ 788 is an endothelin type B (ETB) receptor antagonist and is a potential antidote for the cardiovascular toxicity with hypotension and bradycardia. Group: Biochemicals. Alternative Names: cis-N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine Monosodium Salt; N-[[(2R,6S)-2,6-Dimethyl-1-piperidinyl]carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine Monosodium Salt; (R) -2- ( (R) -2- ( (S) -2- ( (2S, 6R) -2, 6-Dimethylpiperidine-1-carboxamido) -4, 4-dimethylpentanamido) -3- (1- (methoxycarbonyl) -1H-indol-3-yl) propanamido) hexanoic Acid Sodium Salt; N-cis-2, 6-Di methyl piperidinocarbonyl-BETA-tBu-Ala-D-Trp (1-methoxycarbonyl) -D-Nle; BQ 788. Grades: Highly Purified. CAS No. 156161-89-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BQCA
BQCA a highly selective allosteric modulator of the M1 mAChR. Uses: Scientific research. Group: Signaling pathways. CAS No. 338747-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101858.
BQCA
BQCA is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR), as it dose-dependently reduces the concentration of acetylcholine required to activate the M1 receptor. Uses: A highly selective positive allosteric modulator of the m1 muscarinic acetylcholine receptor (machr). Synonyms: 1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 1,4-Dihydro-1-[(4-methoxyphenyl)methyl]-4-oxo-3-quinolinecarboxylic Acid. Grades: ≥98%. CAS No. 338747-41-4. Molecular formula: C18H15NO4. Mole weight: 309.32.
BQR695
BQR695 is a potent and selective PI4K inhibitor exhibiting potency against both human PI4KIIIβ and Plasmodium falciparum asexual blood stages (IC50?values of 90?nM and 71 nM, respectively). Uses: Antimalarial. Synonyms: NVP-BQR695; NVP-BQR-695; NVP-BQR 695; BQR695; BQR-695; BQR 695. NVP-BQR695; CS-8070; HY-18748; CS 8070; HY 18748; CS8070; HY18748; 2-[[7-(3,4-dimethoxyphenyl)quinoxalin-2-yl]amino]-N-methylacetamide. Grades: 99%. CAS No. 1513879-21-4. Molecular formula: C19H20N4O3. Mole weight: 352.39.
BQU57
BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA. Synonyms: BQU57; BQU 57; BQU-57. Grades: >98%. CAS No. 1637739-82-2. Molecular formula: C16H13F3N4O. Mole weight: 334.1.
BR
Bromine is a dark reddish-brown fuming liquid with a pungent odor. Denser than water and soluble in water. Hence sinks in water. Toxic by inhalation. Accelerates the burning of combustible material. It is very corrosive to tissue and to metals.;GasVapor; Liquid;FUMING RED-TO-BROWN LIQUID WITH PUNGENT ODOUR.;Dark reddish-brown, fuming liquid with suffocating, irritating fumes.;Dark reddish-brown, fuming liquid with suffocating, irritating fumes. Group: Polymers. Product ID: molecular bromine. Molecular formula: 159.81g/mol. Mole weight: Br2;Br2. BrBr. InChI=1S/Br2/c1-2. GDTBXPJZTBHREO-UHFFFAOYSA-N.
brachyurin
From hepatopancreas of the fiddler crab, Uca pugilator. In peptidase family S1 (trypsin family). Other serine endopeptidases that degrade collagen, but are not listed separately here, include a second endopeptidase from Uca pugilator, digestive enzymes from other decapod crustacea, and an enzyme from the fungus Entomophthora coronata. Group: Enzymes. Synonyms: Uca pugilator collagenolytic proteinase; crab protease I; crab protease II. Enzyme Commission Number: EC 3.4.21.32. CAS No. 848900-32-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4127; brachyurin; EC 3.4.21.32; 848900-32-3; Uca pugilator collagenolytic proteinase; crab protease I; crab protease II. Cat No: EXWM-4127.
Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Positive Control
Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Positive Control. Group: Molecular Biology. Pack Sizes: 1Vial. US Biological Life Sciences.
Worldwide
Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Primer
Brachyury (Brachyury Homolog, Brachyury Protein, Bry, MGC104817, T, T Protein, TFT), Human, Primer Pair Kit, Primer. Group: Molecular Biology. Pack Sizes: 1Vial. US Biological Life Sciences.
Worldwide
BRACO 19 trihydrochloride
BRACO 19 trihydrochloride is a telomerase inhibitor (IC50 = 115 nM) that suppresses the expression of human telomerase reverse transcriptase (hTERT) and induces cellular senescence. BRACO 19 was shown to inhibit growth of uterine cancer cells in vitro and growth of uterine tumor xenografts in mice. Synonyms: N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride. Grades: ≥95% by HPLC. CAS No. 1177798-88-7. Molecular formula: C35H43N7O2.3HCl. Mole weight: 703.14.
Bradanicline
Bradanicline is a highly selective α7 nicotinic acetylcholine receptor (nAChR) agonist (humanα7 nAChR: EC 50 =17 nM; K i = 1.4 nM). Bradanicline is used for the research of cognitive disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TC-5619. CAS No. 639489-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18060.
Bradanicline
Bradanicline acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studies, and was used as a potential treatment for schizophrenia and attention deficit disorder. It was used for Alzheimer's disease and cognitive impairment, but was discontinued. It was being developed by Targacept and was in phase II trials, but now it is terminated. Uses: Bradanicline was used as a potential treatment for schizophrenia and attention deficit disorder. it was used for alzheimer's disease and cognitive impairment. Synonyms: TC-5619; TC 5619; TC5619; N-[(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]-1-benzofuran-2-carboxamide;TC-5619-023;TC5619-023. Grades: 98%. CAS No. 639489-84-2. Molecular formula: C22H23N3O2. Mole weight: 361.44.
Bradanicline hydrochloride
Bradanicline hydrochloride is Alpha-7 Nicotinic Receptor Agonist. It showed cognitive enhancing effects in animal studies, and was being developed as a potential treatment for schizophrenia and attention deficit disorder. It was discontinued for Alzheimer's disease and cognitive impairment in schizophrenia in late 2013. It was also discontinued for ADHD, and no longer seems to be being developed. Uses: Bradanicline hydrochloride was being developed as a potential treatment for schizophrenia and attention deficit disorder. Synonyms: TC-5619;TC5619;TC-5619-023;TC5619-023;N-((2S,3R)-2-(pyridin-3-ylmethyl)quinuclidin-3-yl)benzofuran-2-carboxamide hydrochloride. Grades: >98%. CAS No. 1111941-90-2. Molecular formula: C22H24ClN3O2. Mole weight: 397.90.
Bradykinin
Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. CAS No. 58-82-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0206.
Bradykinin
Bradykinin is a nonapeptide messenger produced from kallidin in the blood. Bradykinin has the selectivity for B2 over B1 receptors. It exhibits hypotensive and anti-inflammatory properties. Uses: Hypotensive agent. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; L-Bradykinin; Kallidin I; Callidin I; Kallidin 9. Grades: ≥95%. CAS No. 58-82-2. Molecular formula: C50H73N15O11. Mole weight: 1060.21.
Bradykinin 1-3
Bradykinin 1-3, a 3-amino acid residue peptide fragment of Bradykinin, is an amino-truncated Bradykinin cleaved by Prolyl endopeptidase. Synonyms: Bradykinin (1-3); Arginyl-prolyl-proline; arginylprolylproline; L-Arginyl-L-prolyl-L-proline; H-RPP-OH. Grades: 95%. CAS No. 23815-91-0. Molecular formula: C16H28N6O4. Mole weight: 368.43.
Bradykinin(1-3)
Bradykinin(1-3). Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-ARG-PRO-PRO-OH SULFATE;H-ARG-PRO-PRO-OH SULFATE SALT;H-Arg-Pro-Pro-OH;arginyl-prolyl-proline;L-Proline, 1-(1-L-arginyl-L-prolyl)-. Product Category: Heterocyclic Organic Compound. CAS No. 23815-91-0. Molecular formula: C16H28N6O4. Mole weight: 466.51. Product ID: ACM23815910. Alfa Chemistry ISO 9001:2015 Certified.
Bradykinin (1-5)
Bradykinin (1-5) is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE). Uses: Scientific research. Group: Peptides. CAS No. 23815-89-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1488.
Bradykinin 1-5
Bradykinin 1-5 is the main stable metabolite of Bradykinin and is formed by proteolysis of angiotensin-converting enzyme (ACE). Synonyms: H-RPPGF-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanine; Bradykinin (1-5); Bradykinin Fragment 1-5; 1-5-Bradykinin (9Cl); N-[2-({[1-(Arginylprolyl)pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene]phenylalanine. Grades: ≥95%. CAS No. 23815-89-6. Molecular formula: C27H40N8O6. Mole weight: 572.66.
Bradykinin 1-6
Bradykinin 1-6, a stable metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by carboxypeptidase Y (CPY). Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-serine; (S)-2-((S)-2-(2-((S)-1-((S)-1-((S)-2-amino-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoic acid; Bradykinin (1-6). Grades: 95%. CAS No. 23815-88-5. Molecular formula: C30H45N9O8. Mole weight: 659.73.
Bradykinin (2-9)
Bradykinin (2-9) is an amino-truncated Bradykinin peptide. Bradykinin (2-9) is a metabolite of Bradykinin, cleaved by Aminopeptidase P. Uses: Scientific research. Group: Peptides. Alternative Names: Des-Arg1-bradykinin. CAS No. 16875-11-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1490.
Bradykinin 2-9
Bradykinin 2-9, a metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by Aminopeptidase P. Synonyms: Des-Arg1-bradykinin; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Bradykinin fragment 2-9; 2-9-Bradykinin. Grades: ≥95%. CAS No. 16875-11-9. Molecular formula: C44H61N11O10. Mole weight: 904.02.
Bradykinin Fragment 1-7
Bradykinin Fragment 1-7 is a seven-membered oligopeptide. Synonyms: Arg-Pro-Pro-Gly-Phe-Ser-Pro; Des-8,9-BK. Grades: ≥97% by HPLC. CAS No. 23815-87-4. Mole weight: 756.85.
Bradykinin-GN_4 antimicrobial peptide precursor
Bradykinin-GN_4 antimicrobial peptide precursor is originally from Amolops granulosus.
Induces the release of nitric oxide. Other physiological functions include stimulation of pain receptors, inhibition of cAMP accumulation, and induction of smooth muscle contraction and vasodilation. Also involved in edema resulting from trauma or injury. Improves post-ischemic recovery of heart via a nitric oxide-dependent mechanism. Group: Biochemicals. Grades: Highly Purified. CAS No. 58-82-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N??O??. US Biological Life Sciences.
Bradykinin-TR1 bradykinin-related peptide precursor is originally from Amolops granulosus.
B-Raf IN 1
B-Raf IN 1 is a highlt potent and selective B-Raf inhibitor. It was equipotent against c-Raf. Synonyms: B-Raf-IN-1; B-Raf-IN 1; B-Raf-IN1; MDK36057; MDK-36057; MDK 36057. Grades: >98%. CAS No. 950736-05-7. Molecular formula: C29H24F3N5O. Mole weight: 515.53.
B-Raf inhibitor
aA B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases. Synonyms: Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(6-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]-. Grades: >98%. CAS No. 1315330-11-0. Molecular formula: C29H31F3N6O2. Mole weight: 552.59.
BRAF inhibitor
BRAF inhibitor is a B-Raf inhibitor with anti-tumor activity extracted from patent WO/2011103196 A1, Compound P-0850. Uses: Scientific research. Group: Signaling pathways. CAS No. 918505-61-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10247.
B-Raf inhibitor 1
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 μM and 2 nM for A375 proliferation and A375 p-ERK respectively. Synonyms: B-Raf Inhibitor 1; B-Raf-Inhibitor 1; B-Raf-Inhibitor-1; MDK0403; MDK-0403; MDK 0403. Grades: >98%. CAS No. 1093100-40-3. Molecular formula: C26H19ClN8. Mole weight: 478.94.
B-Raf inhibitor 1 dihydrochloride
B-Raf inhibitor 1 is an inhibitor of B-Raf kinase with IC50 values of 0.31μM and 0.72μM for cell proliferation, respectively in A375 and HCT116. B-Raf is important in signal transduction and some mutant B-Raf occurs in cancer cells. The most common mutation of these is V600E, which makes B-Raf kinase constitutively active. B-Raf inhibitor 1 belongs to the type IIA inhibitors and binds to the DFG-out ATP-binding site of B-Raf. The selectivity of B-Raf inhibitor 1 is less than of other type inhibitors. Besides mutant B-Raf, it can also inhibit wild type B-Raf and other tyrosine kinase. In cells with wild type B-Raf, B-Raf inhibitor 1 can activate the RAF-MEK-ERK signaling pathway via Raf dimerization. The preclinical toxicity test shows B-Raf inhibitor 1 can induce hyperplasia in a mouse model. Synonyms: 1,5-Isoquinolinediamine, N1-(4-chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-, hydrochloride (1:2). Grades: >98%. CAS No. 1191385-19-9. Molecular formula: C26H21Cl3N8. Mole weight: 551.86.
Br-AFP1
Br-AFP1 is originally from Brassica rapa subsp. chinensis.
Braftide
Braftide is an allosteric inhibitor for BRAF kinase by targeting the dimer interface of BRAF kinase and inhibiting the formation of BRAF dimers. Braftide inhibits wild-type BRAF and oncogenic BRAF G469A with IC 50 of 364 nM and 172 nM, respectively. Braftide inhibits MAPK signaling pathway, inhibits proliferation of KRAS mutant tumor cells ( EC 50 is 7.1 and 6.6 μM, for HCT116 and HCT-15), in combination of TAT sequence [1]. Uses: Scientific research. Group: Peptides. CAS No. 2411851-64-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10436.
Brahmawood. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Brahmawood;beta,2,2,3-Tetramethylcyclopent-3-ene-1-butanol. Product Category: Heterocyclic Organic Compound. CAS No. 72089-08-8. Molecular formula: C13H24O. Mole weight: 196.329060 [g/mol]. Purity: 0.96. IUPACName: 2-methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)butan-1-ol. Product ID: ACM72089088. Alfa Chemistry ISO 9001:2015 Certified.
Brain Microvascular Endothelial Cells, Human (Frozen)
Passage 2 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplements is recommended for culture. Cells have an average population doubling level of >15 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
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Brain Microvascular Endothelial Cells, Human (T-25 flask)
Passage 2 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplements is recommended for culture. Cells have an average population doubling level of >15 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
Brain natriuretic peptide
Brain natriuretic peptide inhibits angiotensin II-induced blood pressure. Brain natriuretic peptide can be used in the control of blood pressure [1]. Uses: Scientific research. Group: Peptides. Alternative Names: BNP (1-32), human. CAS No. 114471-18-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129067.
Brain natriuretic peptide (1-32) (human)
An agonist at atrial natriuretic peptide (ANP) receptor A (NRP1) which is secreted from cardiac ventricles in response to volume increase and pressure overload. It exhibits natriuretic, vasodilatory and lusitropic activity and suppresses sympathetic and renin-angiotensin-aldosterone systems in vivo, and decreases de novo collagen synthesis as well as increases MMP gene expression in vitro. Synonyms: Brain Natriuretic Peptide-32 human; BNP-32 (human); Nesiritide; H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys(1)-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys(1)-Lys-Val-Leu-Arg-Arg-His-OH; L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminyl-glycyl-L-seryl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-L-histidine (10->26)-disulfide. Grades: ≥99% by HPLC. CAS No. 124584-08-3. Molecular formula: C143H244N50O42S4. Mole weight: 3464.04.
Brain Natriuretic Peptide (1-32) (human) trifluoroacetate salt
Brain natriuretic peptide (BNP) (1-32) is an endogenous peptide that has cardiovascular functions and belongs to the family of natriuretic peptides. It is an agonist of natriuretic peptide receptors (NPRs) 1 and 3 with Kd values of 7.3 and 13 pM, respectively. It also binds to human recombinant NPR1 and NPR3 with IC50 values of 8 and 2.6 nM, respectively. It also relaxes contractions induced by prostaglandin F2α (PGF2α) in isolated porcine coronary artery and rat aortic strips (IC50s = 0.02 and 12.1 nM, respectively). Synonyms: BNP (1-32) (human). Grades: ≥95%. Molecular formula: C143H244N50O42S4·xCF3COOH. Mole weight: 3464.04.
Brain Natriuretic Peptide-45, mouse
Brain Natriuretic Peptide-45, mouse (BNP-45, mouse) is a circulating form of mouse brain natriuretic peptide isolated from mouse heart with potent hypotensive and natriuretic potency [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: BNP-45, mouse. CAS No. 1816939-52-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2469.
Brain Natriuretic Peptide (BNP) (1-32), rat
Brain Natriuretic Peptide (BNP) (1-32), rat is a 32-amino acid polypeptide secreted by the ventricle in response to overstretching of cardiomyocytes. Synonyms: Brain Natriuretic Peptide-32 (rat); BNP (1-32), rat; H-Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys(1)-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys(1)-Asp-Gly-Leu-Arg-Leu-Phe-OH; L-asparagyl-L-seryl-L-lysyl-L-methionyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-seryl-L-arginyl-L-leucyl-glycyl-L-cysteinyl-L-alpha-aspartyl-glycyl-L-leucyl-L-arginyl-L-leucyl-L-phenylalanine (10->26)-disulfide. Grades: 95%. CAS No. 133448-20-1. Molecular formula: C146H239N47O44S3. Mole weight: 3452.94.
Brain (Stripped), Mature, Rabbit
Brain (Stripped), Mature, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 25Ea. US Biological Life Sciences.
Worldwide
Brain (Stripped), Young Rabbit
Brain (Stripped), Young Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 25Ea. US Biological Life Sciences.
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Branaplam
Branaplam (LMI070; NVS-SM1) is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC 50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC 50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LMI070; NVS-SM1. CAS No. 1562338-42-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19620.
Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC 50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC 50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LMI070 hydrochloride; NVS-SM1 hydrochloride. CAS No. 1562338-39-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19620A.
branched-chain-2-oxoacid decarboxylase
Acts on a number of 2-oxo acids, with a high affinity towards branched-chain substrates. The aldehyde formed may be enzyme-bound, and may be an intermediate in the bacterial system for the biosynthesis of branched-chain fatty acids. Group: Enzymes. Synonyms: branched-chain oxo acid decarboxylase; branched-chain α-keto acid decarboxylase; branched-chain keto acid decarboxylase; BCKA; (3S)-3-methyl-2-oxopentanoate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.72. CAS No. 63653-19-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4820; branched-chain-2-oxoacid decarboxylase; EC 4.1.1.72; 63653-19-0; branched-chain oxo acid decarboxylase; branched-chain α-keto acid decarboxylase; branched-chain keto acid decarboxylase; BCKA; (3S)-3-methyl-2-oxopentanoate carboxy-lyase. Cat No: EXWM-4820.
Also acts on L-isoleucine and L-valine, and thereby differs from EC 2.6.1.6, leucine transaminase, which does not. It also differs from EC 2.6.1.66, valine-pyruvate transaminase. Group: Enzymes. Synonyms: transaminase B; branched-chain amino acid aminotransferase; branched-chain amino acid-glutamate transaminase; branched-chain aminotransferase; L-branched chain amino acid aminotransferase; glutamate-branched-chain amino acid transaminase. Enzyme Commission Number: EC 2.6.1.42. CAS No. 9054-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2883; branched-chain-amino-acid transaminase; EC 2.6.1.42; 9054-65-3; transaminase B; branched-chain amino acid aminotransferase; branched-chain amino acid-glutamate transaminase; branched-chain aminotransferase; L-branched chain amino acid aminotransferase; glutamate-branched-chain amino acid transaminase. Cat No: EXWM-2883.
branched-chain-fatty-acid kinase
3-Methylbutanoate, 2-methylbutanoate, pentanoate, butanoate and propanoate can also act as acceptors (cf. EC 2.7.2.7 butyrate kinase). Group: Enzymes. Synonyms: isobutyrate kinase. Enzyme Commission Number: EC 2.7.2.14. CAS No. 84177-54-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3172; branched-chain-fatty-acid kinase; EC 2.7.2.14; 84177-54-8; isobutyrate kinase. Cat No: EXWM-3172.
branched-dextran exo-1,2-α-glucosidase
Does not hydrolyse disaccharides or oligosaccharides containing linear 1,2-α-glucosidic linkages. Group: Enzymes. Synonyms: dextran 1,2-α-glucosidase; dextran α-1,2 debranching enzymel 1,2-α-D-glucosyl-branched-dextran 2-glucohydrolase. Enzyme Commission Number: EC 3.2.1.115. CAS No. 72840-94-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3798; branched-dextran exo-1,2-α-glucosidase; EC 3.2.1.115; 72840-94-9; dextran 1,2-α-glucosidase; dextran α-1,2 debranching enzymel 1,2-α-D-glucosyl-branched-dextran 2-glucohydrolase. Cat No: EXWM-3798.
Branched PEI-g-PEG
PEI-g-PEG is a graft copolymer of branched PEI (bPEI), which is modified with multiple PEGs of indicated MW. The PEG to PEI ratio is the average number of PEGs per PEI. Uses: Copolymers of cationic poly(ethyleneimine) wight grafted with polyethylene glycol (peg) (pei-g-peg) are extremely well-studied compounds that markedly improve the in vitro and in vivo delivery of oligonucleotides (aos) to cells and tissues. by varying the mw of pei, as well as the nature of peg shielding, peg-pei-ao nanoparticulates can be prepared with a dynamic range of size, surface charge, and stability. each of these properties in-turn influences the transfection capacity of the peg-pei-ao polyplexes. in addition, peg-pei copolymers are readily functionalized for enhanced efficacy and specificity of cellular and tissue targeting. Group: Hydrophilic polymers. Alternative Names: PEI-PEG, Branched polyethylenimine-graft-poly(ethylene glycol), PEI-g-PEG. Molecular formula: PEG Mn 550. Mole weight: H3CO[ (CH2)2O]nC12H23N3O3[NH (CH2)2]mNH2.
Brandioside
Brandioside is found in the herbs of Verbena officinalis. Brandioside exhibits inhibitory effect on advanced glycation end product formation and smooth muscle cell proliferation. Synonyms: 2'-O-Acetylpoliumoside; [5-acetyloxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-2-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate. Grades: >98%. CAS No. 133393-81-4. Molecular formula: C37H48O20. Mole weight: 812.771.
Brandioside
Brandioside. Group: Biochemicals. CAS No. 133393-81-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Branebrutinib
Branebrutinib (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Brutons tyrosine kinase (BTK) , with an IC 50 of 0.1 nM [1] [2]. Branebrutinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986195. CAS No. 1912445-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112161.
Br-ANT-ATP
Br-ANT-ATP is an analogue of adenosine-5'-triphosphate, of which the intrinsic fluorescence would increase in hydrophobic environment. It can be used for research into ATP-dependent receptor proteins. Synonyms: 2'- / 3'- O- (5- Bromoanthraniloyl)adenosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1350521-49-1. Molecular formula: C17H20BrN6O14P3 (free acid). Mole weight: 705.2 (free acid).
Brasilicardin A
Brasilicardin A is a tricyclic diterpene antibiotic produced by Nocardia brasiliensis IFM 0406. It has no antibacterial activity and has an immunosuppressive effect. Molecular formula: C45H68N2O16. Mole weight: 893.02.
Brasilinolide A
Brasilinolide A is a lactone produced by Nocardia brasiliensis. Synonyms: Propanedioic acid, mono(14-(6-((2,6-dideoxy-3-O-(1-oxopentyl)-beta-D-lyxo-hexopyranosyl)oxy)-2,4-dihydroxy-1,3,5-trimethylheptyl)-3,9,20,22,24,28,30,31,32-nonahydroxy-13,27-dimethyl-16-oxo-11,15,34-trioxatricyclo(28.3.1.0(sup 10,12))tetratriacont-17-en-5-yl) ester; 3-[[2,4-dihydroxy-6-(5-hydroxy-6-methyl-4-pentanoyloxy-tetrahydropyran-2-yl)oxy-1,3,5-trimethyl-heptyl]-nonahydroxy-dimethyl-oxo-[?]yl]oxy-3-oxo-propanoic acid. CAS No. 179041-27-1. Molecular formula: C57H98O24. Mole weight: 1167.37.
Brasilinolide B
Brasilinolide B is a lactone produced by Nocardia brasiliensis. Synonyms: (1R, 3R, 5R, 9S, 10S, 12S, 13R, 14R, 17E, 20S, 22R, 24S, 27R, 28R, 30S, 31R, 32S)-14-{(2S, 3S, 4R, 5R, 6R, 7S)-7-[(2, 6-dideoxy-3, 4-di-O-methyl-alpha-L-lyxo-hexopyranosyl)oxy]-3, 5-dihydroxy-4, 6-dimethyloctan-2-yl}-3, 9, 20, 22, 24, 28, 30, 31, 32-nonahydroxy-13, 27-dimethyl-16-oxo-11, 15, 34-trioxatricyclo[28.3.1.0(10, 12)]tetratriacont-17-en-5-yl methyl butylpropanedioate. CAS No. 262596-89-4. Molecular formula: C59H104O23. Mole weight: 1181.44.
Brasiliquinone A
Brasiliquinone A is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis, which has anti-gram-positive bacteria and tumor activity. Synonyms: (3S)-3-ethyl-6-hydroxy-1,7,12-trioxo-1,2,3,4,7,12-hexahydrotetraphen-8-yl 3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranoside. CAS No. 183201-02-7. Molecular formula: C26H27NO7. Mole weight: 465.49.
Brasiliquinone B
Brasiliquinone B is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis, which has anti-gram-positive bacteria and tumor activity. Synonyms: (3S)-3-ethyl-6,8-dihydroxy-3,4-dihydrotetraphene-1,7,12(2H)-trione. CAS No. 183201-04-9. Molecular formula: C20H16O5. Mole weight: 336.34.