A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Bevirimat (PA-457, MPC-4326, YK FH312) is an inhibitor of HIV-1 viral particle maturation.Bevirimat specifically inhibits the final rate-limiting step in Gag processing, preventing the release of the mature capsid protein (CA) from its precursor (CA-SP1), resulting in the production of immature non-infectious viral particles. Bevirimat can be used in HIV-1 infection studies [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: PA-457; MPC-4326; YK FH312. CAS No. 174022-42-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0842.
Bevirimat
Bevirimat, also known as MPC-4326 and PA-457, is an anti-HIV drug derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum, a Chinese herb. It is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. Like protease inhibitors, bevirimat and other maturation inhibitors interfere with protease processing of newly translated HIV polyprotein precursor, called gag. Bevirimat prevents this viral replication by specifically inhibiting cleavage of the capsid protein (CA) from the SP1 spacer protein. Synonyms: MPC4326; MPC 4326; MPC-4326; PA457; PA 457; PA-457; FH11327; FH-11327; FH 11327; YK FH312; Bevirimat; YKFH312. Grades: >98%. CAS No. 174022-42-5. Molecular formula: C36H56O6. Mole weight: 584.83.
Bevonium methylsulfate (CG-201) is an injection that stimulates antibodies to block the pathological forms of hCG that help cancer cells grow and evade the immune system. CG201 was originally created in collaboration with the World Health Organization as a low-cost contraceptive method for developing countries. CG201 is now approved for a Phase I clinical trial in Sweden. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: CG-201; CG 201; CG201; Bevonium methyl sulfate; Piribenzil methyl sulfate; 2-((2-hydroxy-2,2-diphenylacetoxy)methyl)-1,1-dimethylpiperidin-1-ium methyl sulfate. Grades: 98%. CAS No. 5205-82-3. Molecular formula: C23H31NO7S. Mole weight: 465.56.
Bevonium methyl sulfate
Bevonium methyl sulfate. Group: Biochemicals. Alternative Names: 2-[(2-Hydroxy-1-oxo-2,2-diphenylethoxy)methyl]-1,1-dimethylpiperidinium methyl sulfate; Acabel; Bevonium metilsulfate. Grades: Highly Purified. CAS No. 5205-82-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H31NO7S. US Biological Life Sciences.
Used as an anticholinergic, antispasmodic, and brochodilator. Group: Biochemicals. Alternative Names: 2-[(2-Hydroxy-1-oxo-2,2-diphenylethoxy)methyl]-1,1-dimethylpiperidinium, Methyl Sulfate. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Bevurogant
Bevurogant is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Synonyms: 8-[(1S)-1-cyclopropylethyl]-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-6-({[5-(methanesulfonyl)pyridin-2-yl]methyl}amino)pteridin-7(8H)-one; 8-((S)-1-Cyclopropyl-ethyl)-2-(4-cyclopropyl-6-methyl-pyrimidin-5-yl)-6-[(5-methanesulfonyl-pyridin-2-ylmethyl)-amino]-8H-pteridin-7-one; (S)-2-(4-cyclopropyl-6-methylpyrimidin-5-yl)-8-(1-cyclopropylethyl)-6-(((5-(methylsulfonyl)pyridin-2-yl)methyl)amino)pteridin-7(8H)-one. CAS No. 1817773-66-2. Molecular formula: C26H28N8O3S. Mole weight: 532.62.
Bexarotene
Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. Synonyms: LGD1069; LGD 1069; LGD-1069; LG 100069; Ro 26-445; SR 11247; 3-methyl TTNEB. Bexarotene; US brand name: Targretin. Grades: >98%. CAS No. 153559-49-0. Molecular formula: C24H28O2. Mole weight: 348.
Bexarotene. Group: Biochemicals. Alternative Names: 4-[1- (5, 6, 7, 8-Tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) ethenyl) benzoic acid; LG 100069; LG 1069. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 100mg. Molecular Formula: C24H28O2. US Biological Life Sciences.
Worldwide
Bexarotene
Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors ( RXR ) agonist with EC 50 s of 33, 24, 25 nM for RXRα , RXRβ , and RXRγ , respectively. Bexarotene shows limited affinity for RAR receptors (EC 50 >10000 nM) [1] [2] [3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGD1069. CAS No. 153559-49-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-14171.
Bexarotene-13C4
Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Bexarotene-13C4 Methyl Ester
Protected Bexarotene. Used as an antineoplastic. Also used in the preparation of bexarotene analogs as RXR selective agonists. Group: Biochemicals. Alternative Names: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-benzoic Acid Methyl Ester-13C4; Methyl 4-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-ethenyl]benzoate-13C4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce AB40 and AB42 levels in APP/PS1 mice in an ApoE-dependent manner (25% reduction in 6h and 50% reduction in 72h). Causes a rapid reversal of cognitive, social, and olfactory deficts. Shown to progressively enhance the expression of ApoE and ATP-binding cassette transporters ABCA1 and ABCG1. Also stimulates the secretion of highly lapidated HDL particles in primary microglia and astrocytes. Does not affect the levels of AB proteases, insulin degrading enzyme, and neprilysin. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 50mg. US Biological Life Sciences.
Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist. Group: Biochemicals. Alternative Names: 4-[1- (5, 6, 7, 8-Tetrahydro-3, 5, 5, 8, 8-pentamethyl-2-naphthalenyl) ethenyl) benzoic Acid, SR-11247, LGD-1069, Targretin. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Bexarotene Acyl Glucuronide
Bexarotene Acyl Glucuronide is a glucuronide metabolite of Bexarotene. Synonyms: Bexarotene Acyl-β-D-glucuronide; 1-[4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentaMethyl-2-naphthalenyl)ethenyl]benzoate] β-D-Glucopyranuronic Acid. Grades: > 95%. CAS No. 198700-33-3. Molecular formula: C30H36O8. Mole weight: 524.62.
Bexarotene (LGD-1069) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas (CTCL). Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Bexarotene Impurity 3
Bexarotene Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate. CAS No. 153559-48-9. Molecular formula: C25H30O2. Mole weight: 362.51. Catalog: APB153559489.
Bexarotene Impurity 4
Bexarotene Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoate. CAS No. 153559-45-6. Molecular formula: C24H28O3. Mole weight: 364.49. Catalog: APB153559456.
Bexarotene (Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247)
Bexarotene (also called Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas. The receptor-selective retinoids might be particularly useful in preventing ER-negative breast cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 5mg. Molecular Formula:C24H28O2 MOLECULAR WEIGHT: 348.48. US Biological Life Sciences.
Worldwide
Bexicaserin
Bexicaserin (LP352) is a 5-HT2C receptor agonist with potential for studying obesity and psychiatric-related disorders (such as epilepsy) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LP352. CAS No. 2035818-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156601.
Bexmarilimab
Bexmarilimab (FP-1305) is a potent humanized anti- CLEVER-1 IgG4-antibody with an IC 50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FP-1305. CAS No. 2259301-27-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99236.
Bexmarilimab
Bexmarilimab is a humanized monoclonal antibody against Clever-1, a macrophage scavenger receptor known to induce intratumoural immunosuppression. Bexmarilimab has been investigated for the treatment of solid tumors. Synonyms: FP-1305; FP 1305; FP1305. CAS No. 2259301-27-2.
Bexotegrast
Bexotegrast (PLN-74809) is an orally active, potent dual αvβ6/αvβ1 integrin inhibitor with K d of 5.7 nM and 3.4 nM, respectively. Bexotegrast inhibits αvβ6- and αvβ1-induced TGF-β activation with IC 50 values of 29.8 nM and 19.2 nM, respectively. Bexotegrast has antifibrogenic effects and block multiple avenues of TGF-β activation in the fibrotic lung [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLN-74809. CAS No. 2376257-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137561.
Beyerol
It is produced by the strain of Beyeria (euphorbiaceae) leschenaultii (DC) Bail. Synonyms: (+)-Beyerol; (+)-15-beyerene-3alpha,17,19-triol; NSC83440; ((3R,4R,4aS,6aR,9R,11aS,11bS)-3-hydroxy-4,11b-dimethyl-2,3,4,4a,5,6,10,11,11a,11b-decahydro-6a,9-methanocyclohepta[a]naphthalene-4,9(1H)-diyl)dimethanol; (4R,8R,13R)-13-(Hydroxymethyl)-17-norkaur-15-ene-3α,18-diol; 17-Norkaur-15-ene-3,18-diol, 13-(hydroxymethyl)-, (3α,4α,8β,13β)-. CAS No. 6040-48-8. Molecular formula: C20H32O3. Mole weight: 320.47.
Beyerol 17-cinnamate
It is produced by the strain of Beyeria (euphorbiaceae) leschenaultii var. drummondii. Synonyms: 17-Norkaur-15-ene-3,18-diol, 13-[[(1-oxo-3-phenyl-2-propen-1-yl)oxy]methyl]-, (3alpha,4alpha,8beta,13beta)-; 17-Norkaur-15-ene-3,18-diol, 13-[[(1-oxo-3-phenyl-2-propen-1-yl)oxy]methyl]-, (3α,4α,8β,13β)-; beyerol 17-monocinnamate; (8β,13R)-13-Cinnamoyloxymethyl-17-norkaur-15-ene-3β,18-diol; ((3R,4R,4aS,6aR,9R,11aS,11bS)-3-hydroxy-4-(hydroxymethyl)-4,11b-dimethyl-2,3,4,4a,5,6,10,11,11a,11b-decahydro-6a,9-methanocyclohepta[a]naphthalen-9(1H)-yl)methyl cinnamate. CAS No. 59219-79-3. Molecular formula: C29H38O4. Mole weight: 450.61.
Beyerol, dihydro-, triacetate
Cas No. 105403-79-0. Molecular formula: C26H40O6. Mole weight: 448.59.
Beyerol triacetate
Cas No. 102216-95-5. Molecular formula: C26H38O6. Mole weight: 446.58.
Beyeryl tribenzoate
Cas No. 106068-02-4. Molecular formula: C41H44O6. Mole weight: 632.78.
BEZ235 Tosylate
BEZ235 tosylate is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Synonyms: NVP-BEZ235; BEZ 235 Tosylate; BEZ-235 Tosylate. Grades: >98%. CAS No. 1028385-32-1. Molecular formula: C37H31N5O4S. Mole weight: 641.74.
Bezafibrate is an agonist of PPAR , with EC 50 s of 50 μM, 60 μM, 20 μM for human PPARα , PPARγ and PPARδ , and 90 μM, 55 μM, 110 μM for murine PPARα , PPARγ and PPARδ , respectively; Bezafibrate is used as an hypolipidemic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BM15075. CAS No. 41859-67-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0637.
Bezafibrate
Bezafibrate. Group: Biochemicals. Alternative Names: 2-[4-[2-[ (4-Chlorobenzoyl) amino]ethyl]phenoxyl]-2-methylpropanoic acid; BM-15075; Befizal. Grades: Highly Purified. CAS No. 41859-67-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C19H20ClNO4. US Biological Life Sciences.
Worldwide
Bezafibrate
Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used for the treatment of hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL. Uses: Hypolipidemic agents. Synonyms: BM 15075; BM15075; BM-15075. Grades: >98%. CAS No. 41859-67-0. Molecular formula: C19H20ClNO4. Mole weight: 361.82.
Antilipemic. Group: Biochemicals. Alternative Names: 2-[4-[2-[ (4-Chlorobenzoyl) amino]ethyl]phenoxyl]-2-methylpropanoic Acid;BM-15075; Befizal; Bezalip; Bezatol; Cedur; Difaterol. Grades: Highly Purified. CAS No. 41859-67-0. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
Bezafibrate Impurity D
Bezafibrate Impurity D is a derivative of Bezafibrate. Synonyms: Bezafibrate Ethyl Ester; 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic Acid Ethyl Ester; Ethyl 2-(4-(2-(4-Chlorobenzamido)ethyl)phenoxy)-2-methylpropanoate. Grades: > 95%. CAS No. 41859-58-9. Molecular formula: C21H24ClNO4. Mole weight: 389.88.
Bezisterim
Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis [1] [2] [3]. Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HE 3286; NE-3107. CAS No. 1001100-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108039.
Bezlotoxumab
Bezlotoxumab is a human monoclonal antibody directed against C. difficile toxin B. Bezlotoxumab binds to C. difficile toxin B preventing intestinal epithelial damage and colitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1246264-45-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9929.
Bezuclastinib
Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor with potent activity against KIT D816V. Bezuclastinib can be used for the research of nonadvanced systemic mastocytosis (NonAdvSM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGT9486; PLX 9486. CAS No. 1616385-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145557.
BF2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,6-Bis((E)-4-(diphenylamino)styryl)-5-(ethoxycarbonyl)-2,2-difluoro-2H-1,3,2-dioxaborinin-1-ium-2-uide. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2243376-97-6. Molecular formula: C46H37BF2N2O4. Mole weight: 730.6 g/mol. Product ID: ACM2243376976. Alfa Chemistry ISO 9001:2015 Certified.
BF 2649
Pitolisant hydrochloride is an antagonist of the histamine H3 receptor, which is used for the treatment of narcolepsy with or without cataplexy in adult patients. Uses: The treatment of narcolepsy with or without cataplexy. Synonyms: BF 2649; BF2649; BF-2649; pitolisant hydrochloride; Wakix; 1-[3-[3- (4-chlorophenyl) propoxy]propyl]piperidine hydrochloride. CAS No. 903576-44-3. Molecular formula: C17H27Cl2NO. Mole weight: 332.309.
BF 2649 hydrochloride
BF 2649 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 903576-44-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BF 738735
A potent and selective ATP-competitive phosphatidylinositol 4-kinase III beta (PI 4-KIIIβ) inhibitor (IC50 = 5.7 nM). Displays approximately 200-fold selectivity over PI 4-KIII&alpha. Broad spectrum enterovirus replication inhibitor. Synonyms: 2-Fluoro-4-[2-methyl-8-[[[3- (methylsulfonyl) phenyl]methyl]amino]imidazo[1, 2-a]pyrazin-3-yl]phenol; BF738735; BF-738735. Grades: ≥98%. CAS No. 1436383-95-7. Molecular formula: C21H19FN4O3S. Mole weight: 426.47.
BF844
BF844 is a CLRN1N48K stabilizer that can attenuate progressive hearing loss and deafness in an Usher syndrome type III (USH3) mouse model. Uses: Hearing loss therapy. Synonyms: BioFocus 844; BioFocus844; BioFocus-844; BF844; BF-844; BF 844; 4-Chloro-α,α-dimethyl-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine-1-ethanol. Grades: 98%. CAS No. 1404506-35-9. Molecular formula: C21H19ClN4O. Mole weight: 378.85.
B-factor
B-factor is extracted from yeast. Synonyms: 3'-(1-Butylphosphoryl)adenosine; 3'-Adenylic acid, monobutyl ester. CAS No. 52278-63-4. Molecular formula: C14H22N5O7P. Mole weight: 403.33.
BFB
BFB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Poly[(9,9-dioctylfluorenyl-2,7-diyl)-alt-(N,N'-bis{4-butylphenyl}-benzidine-N,N'-{1,4-diphenylene})]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 223569-32-2. Molecular formula: (C73H82N2)n. Product ID: ACM223569322. Alfa Chemistry ISO 9001:2015 Certified.
BFCAs-1
BFCAs-1 is a polyamino polycarboxylic bifunctional chelating agent, which has a broad range of applications in chemistry, biology and medicine and diagnostic imaging. Grades: >98%. CAS No. 585531-74-4. Molecular formula: C32H60N4O8. Mole weight: 628.84.
BF-CATH
Cathelicidin-BF is a short antimicrobial peptide, which was originally extracted from the venom of Bungarus fasciatus. Recent studies have reported that Cath-BF and some related derivatives exert strong antimicrobial and weak hemolytic properties. Synonyms: Cath-BF.
BF-DPB
BF-DPB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4,N4'-Bis(9,9-dimethyl-9H-fluoren-2-yl)-N4,N4'-diphenylbiphenyl-4,4'-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 361486-60-4. Molecular formula: C54H44N2. Mole weight: 720.94 g/mol. Purity: 95%+. IUPACName: N-[4-[4-(N-(9,9-dimethylfluoren-2-yl)anilino)phenyl]phenyl]-9,9-dimethyl-N-phenylfluoren-2-amine. Canonical SMILES: CC1(C2=CC=CC=C2C3=C1C=C(C=C3)N(C4=CC=CC=C4)C5=CC=C(C=C5)C6=CC=C(C=C6)N(C7=CC=CC=C7)C8=CC9=C(C=C8)C1=CC=CC=C1C9(C)C)C. Density: 1.178 ± 0.06 g/ml. Product ID: ACM361486604. Alfa Chemistry ISO 9001:2015 Certified.
BFF 122
BFF 122 is a potent and selective inhibitor of kynurenine aminotransferase II (IC50 = 1 μM and >30 μM for KAT II and KAT I respectively). Synonyms: BFF122; BFF 122; BFF-122; BF5; (S)-9-(4-Amino-piperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid. Grades: 99%. CAS No. 1152314-49-2. Molecular formula: C17H19FN4O4. Mole weight: 362.36.
BFH772
BFH772, a structure analogue of BAW2881, was highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM, however, lost 500-fold potency on FLK-1, FLT-1, and FLT-4. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM. Synonyms: 6-[[6-(hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide; BFH-772; BFH 772; BFH772; 1-Naphthalenecarboxamide, 6-((6-(hydroxymethyl)-4-pyrimidinyl)oxy)-N-(3-(trifluoromethyl)phenyl)-. CAS No. 890128-81-1. Molecular formula: C23H16F3N3O3. Mole weight: 439.4.
b-Fluoro-DL-alanine
b-Fluoro-DL-alanine. Group: Biochemicals. Grades: Highly Purified. CAS No. 43163-93-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C3H6FNO2. US Biological Life Sciences.
Worldwide
b-Fluoro-DL-alanine ≥97% (GC)
b-Fluoro-DL-alanine ≥97% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 100mg, 250mg, 25mg, 1g. US Biological Life Sciences.
BG45 is a class I HDAC inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3, HDAC1, HDAC2, and HDAC6 in cell-free assays, respectively. Synonyms: BG45; BG-45; BG 45. Grades: 98%. CAS No. 926259-99-6. Molecular formula: C11H10N4O. Mole weight: 214.22.
b-Galactosyl 1-3 N-acetyl galactosamine methyl glycoside is a sophisticated compound, functioning as an artfully engineered synthetic glycoside. Thereby, it orchestrates nuanced manipulation of cellular processes instrumental in compound administration, focused therapeutics, or malady identification. Synonyms: Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-galactopyranoside; β-Galactosyl 1-3 N-acetyl galactosamine methyl glycoside; N-Acetyl-3-O-beta-D-galactopyranosyl-beta-D-galactosamine methyl glycoside; N-Acetyl-3-O-β-D-galactopyranosyl-β-D-GA. Grades: ≥98%. CAS No. 88274-25-3. Molecular formula: C15H27NO11. Mole weight: 397.38.
b-Galactosylceramides - from bovine brain
Cas No. 85305-88-0.
BGB-283
BGB-283 is a selective Epidermal growth factor receptor and Proto oncogene protein b raf inhibitor under the development of BeiGene. BGB-283 shows antitumor activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 can inhibit B-RAFV600E-activated ERK phosphorylation and cell proliferation. In vivo, BGB-283 can lead to dose-dependent tumor growth inhibition accompanied by partial and complete tumor regressions in both cell-line derived and primary human colorectal tumor xenografts bearing B-RAFV600E mutation. Phase I clinical trials for the treatment of solid tumours are on-going. Uses: Solid tumours. Synonyms: UNII-8762XZS5ZF; 8762XZS5ZF; BGB-283; BGB 283; BGB283; Beigene-283; Beigene283; Beigene 283; Lifirafenib; Compound 2.2b; Beigene-283; GTPL8958;5-[[(1R,1aS,6bR)-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one. Grades: 98%. CAS No. 1446090-77-2. Molecular formula: C25H17F3N4O3. Mole weight: 478.31.
BGB-3111
BGB-3111 is a potent, selective and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability, achieving higher exposure and more complete target inhibition in the tissues than ibrutinib. Uses: Antineoplastic agents. Synonyms: 2-(4-phenoxyphenyl)-7-(1-prop-2-enoylpiperidin-4-yl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide; SCHEMBL16208602; BDBM249900; BGB-3111; BGB 3111; BGB3111. CAS No. 1633350-06-7. Molecular formula: C27H29N5O3. Mole weight: 471.55.
BGC-20-1531 free base
BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP 4 receptor antagonist, with a pK B of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PGN 1531 free base. CAS No. 736183-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19849.
BGC 20-1531 hydrochloride
BGC 20-1531 hydrochloride is a potent and selective EP4 antagonist, which exhibits <50% inhibition at 47 ion channels, cell-surface transporters, enzymes, and nuclear receptors. It has high affinity and selective with Ki of 3 nM for EP4 antagonist. BGC 20-1531 antagonizes PGE2-induced cAMP accumulation in a dose-dependent manner in HEK293 EBNA. It also reverses PGE2-induced vasorelaxation with Kb of 15.85 nM in human middle cerebral and middle meningeal arterial rings. Synonyms: BGC20-1531 HCl; BGC20-1531 hydrochloride; BGC20-1531; BGC 20-1531; BGC-20-1531; BGC201531; BGC 201531; BGC-201531; PGN 1531; PGN-1531; PGN1531. Grades: ≥98%. CAS No. 1962928-26-2. Molecular formula: C26H24N2O6S·HCl. Mole weight: 529.
BGC 20-761
BGC 20-761 is a selective, high affinity 5-HT6 antagonist (Ki = 20 nM). BGC 20-761 was shown to reverse the amnesic effects of scopolamine and enhance memory consolidation in a rat model. Synonyms: BGC-20-761; BGC 20 761; 5-Methoxy-N,N-dimethyl-2-phenyl-1H-indole-3-ethanamine; N,N-Dimethyl-2-(5-methoxy-2-phenylindol-3-yl)ethylamine. Grades: ≥98% by HPLC. CAS No. 17375-63-2. Molecular formula: C19H22N2O. Mole weight: 294.39.
BGC 20-761
BGC 20-761. Group: Biochemicals. Grades: Purified. CAS No. 17375-63-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BGC-638
BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. Synonyms: BGC 638; BGC638; CB300638; CB-300638; D-Glutamic acid, N-(4-(2-propyn-1-yl((6S)-4,6,7,8-tetrahydro-2-methyl-4-oxo-3H-cyclopenta(g)quinazolin-6-yl)amino)benzoyl)-L-gamma-glutamyl-. CAS No. 416852-27-2. Molecular formula: C32H33N5O9. Mole weight: 631.64.
BGC-945
BGC 945 is a cyclopenta[g]quinazoline-based, thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. BGC 945 has low affinity for the widely expressed reduced-folate carrier (RFC). BGC 945 selectively inhibits thymidylate synthase in α-FR-overexpressing tumors and should cause minimal toxicity to humans at therapeutic doses. Synonyms: Idetrexed; ONX-0801; N-[4-[2-Propynyl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-1H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; (R) -2- ( (S) -4-carboxy-4- (4- ( ( (S) -2- (hydroxymethyl) -4-oxo-4, 6, 7, 8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl) (prop-2-yn-1-yl) amino) benzamido) butanamido) pentanedioic acid. Grades: ≥95%. CAS No. 501332-69-0. Molecular formula: C32H33N5O10. Mole weight: 647.63.
b-Gentiobiose octaacetate
b-Gentiobiose octaacetate is a biomedical compound employed extensively in drug development and research, predominantly recognized as a safeguarding tool for delicate pharmaceuticals. This compound remarkably aids drug delivery and augments stability. Moreover, its application extends to the investigation of ailments such as cancer, diabetes and neurodegenerative disorders, thereby effectively unraveling their intricate mechanisms and potential researchs. Synonyms: 1,2,3,4-Tetra-O-acetyl-6-O-(2,3,4,6-tetra-O-acetyl-b-D-glucopyranosyl)-b-D-glucopyranose. CAS No. 4613-78-9. Molecular formula: C28H38O19. Mole weight: 678.59.
BGJ-398
BGJ398, also known as NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Synonyms: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea; NVPBGJ398; NVPBGJ 398; NVPBGJ-398; BGJ398; BGJ-398; BG J398; Infigratinib. Grades: 0.98. CAS No. 872511-34-7. Molecular formula: C26H31Cl2N7O3. Mole weight: 560.48.
Bgl I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500U; 2500U. GCCNNNN↑NGGC CGGN↓NNNNCCG. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer 2W. Storage: -20°C. Form: Liquid. Source: Bacillus globigii. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1033RE.