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| Product | Description | |
|---|---|---|
| Bgl II | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. A↑GATCT TCTAG↓A. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Bgl II gene from Bacillus globigii. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1034RE. |  |
| b-Glucan | b-1,3/1-4-glucan from oat. dietary fiber supplement. CAS No. 55965-23-6. Product ID: 4-00692. Purity: 0.9. |  |
| b-Glucan | b-1,3-glucan. CAS No. 9012-72-0. Product ID: 4-00100. Purity: 0.95. | |
| b-Glucan | b-1,3-glucan. CAS No. 9012-72-0. Product ID: 4-00302. Purity: 0.75. Properties: water soluble. | |
| b-Glucan | b-1,3-glucan. CAS No. 9012-72-0. Product ID: 4-00501. Purity: 0.7. Source : from Saccharomyces cerevisiae. | |
| b-Glucan | b-1,3-glucan. CAS No. 9012-72-0. Product ID: 4-00502. Purity: 0.5. | |
| b-Glucan | b-1,3-glucan sodium hydroxide soluble fraction. CAS No. 9012-72-0. Product ID: 4-00562. Source : from Saccharomyces cerevisiae. | |
| b-Glucan | b-1,3-glucan acetic acid soluble fraction. CAS No. 9012-72-0. Product ID: 4-00563. Source : from Candida albicans. | |
| b-Glucan | b-1,3/1-4-glucan from oat. CAS No. 55965-23-6. Product ID: 4-00693. Purity: 0.8. | |
| b-Glucan | b-1,3-glucan. CAS No. 9012-72-0. Product ID: 4-00564. Properties: powder. Source : ex Gelidium sp. | |
| b-Glucan | b-1,6-glucan. CAS No. 9012-72-0. Product ID: 4-00592. Purity: 54% b-glucan. Properties: moisture <12%, gel strength 1,000 g/cm2, pH 7-9. | |
| b-Glucan aldehyde | b-1,3-glucan. Product ID: 5-00152. | |
| b-Glucan dialdehyde | b-1,3-glucan with dialdehyde at non-reducing and reducing termini. suitable for selective substitution at C-6 hydroxyl groups. Product ID: 5-02606. Reference: Macromolecules, 29, 2392, 1996; Carbohydr. Res. 220, 173, 1991; Carbohydr. Res. 238, 231, 1993. | |
| b-Glucosylglycerol 2,3,4,6-tetraacetate | b-Glucosylglycerol 2,3,4,6-tetraacetate, a remarkable compound, exhibits immense potential as an antidiabetic agent. In the realm of diabetes management, this prodigious specimen reigns, adeptly regulating blood glucose levels and fostering insulin sensitivity enhancement. Beyond its primary scope, it gracefully unveils itself as a viable therapeutic alternative for diverse metabolic afflictions. Synonyms: 2-(Tetraacetylglucosido)glycerol; 2-Hydroxy-1-(hydroxymethyl)ethyl b-D-glucopyranoside 2,3,4,6-tetraacetate; 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl glycerol. CAS No. 157024-67-4. Molecular formula: C17H26O12. Mole weight: 422.38. |  |
| b-Glucuronidase Inhibitor (1-((6,8-Dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-3-(4-ethoxyphenyl)-1-(2-hydroxyethyl)thiourea) | An orally bioavailable trisubstituted thiourea compound that acts as a potent, uncompetitive and reversible inhibitor of bacterial b-glucuronidase activity (IC50 = 283nM; kcat/Km=0.0987s-1uM-1; Ki4nM in vitro assays against E. coli b-glucuronidase; EC50.7nM in b-glucuronidase expressing HB101 cells) with excellent selectivity over mammalian b-glucuronidases. Shown to directly target the 17-residue (360-376) loop structure that protects the active site of E. coli b-glucuronidase and alter its conformation. Displays negligible cytotoxicity toward both bacterial and mammalian epithelial cells (>100uM for HCT116, Caco-2 and CMT93 colon cancer cells) and offers protection against CPT-11 (50mg/kg, i.p., s.i.d. for 9 days)-induced toxicity in mice (10ug, p.o., b.i.d). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| b-Glutamic acid hydrochloride 98+% (TLC) | b-Glutamic acid hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 336182-10-6. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| b-Glycerophosphate Disodium Salt Hydrate 99+% | Used as an organic phosphate donor and to buffer cell culture media. Group: Biochemicals. Alternative Names: Glycerol 2-phosphate disodium salt hydrate. Grades: Reagent Grade. CAS No. 154804-51-0. Pack Sizes: 5g, 25g, 100g, 250g. Molecular Formula: C3H7Na2O6P; xH2O, Molecular Weight: 234. US Biological Life Sciences. | Worldwide |
| b-Glycerophosphoric acid disodium salt pentahydrate | b-Glycerophosphoric acid disodium salt pentahydrate. Group: Biochemicals. Alternative Names: Disodium b-glycerophosphate pentahydrate; Glycerol 2-phosphate disodium salt pentahydrate. Grades: Highly Purified. CAS No. 819-83-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C3H7O6P·2Na·5H2O. US Biological Life Sciences. | Worldwide |
| BGP-15 | BGP-15 is a PARP inhibitor, with an IC50 and a Ki of 120 and 57 μM, respectively. Uses: Enzyme inhibitors. Synonyms: BGP15; BGP 15; 3-Pyridinecarboximidamide, N-(2-hydroxy-3-(1-piperidinyl)propoxy)-, hydrochloride (1:2). Grades: >98%. CAS No. 66611-37-8. Molecular formula: C20H40N4O3S3. Mole weight: 351.27. | |
| BGP-15 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BGT226 | BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. BGT226 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, which may trigger the translocation of cytosolic Bax to the mitochondrial outer membrane, increasing mitochondrial membrane permeability. Synonyms: BGT-226; BGT 226; BGT-226 free base; BGT226 free base; NVP-BGT226; 1,3-Dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-2H-imidazo[4,5-c]quinolin-2-one. Grades: 98%. CAS No. 915020-55-2. Molecular formula: C32H29F3N6O6. Mole weight: 534.54. | |
| Bh3i-1 | BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 300817-68-9. Molecular formula: C15H14BrNO3S2. Mole weight: 400.316. Purity: ≥98.0%. Product ID: ACM300817689. Alfa Chemistry ISO 9001:2015 Certified. Categories: BH3 interacting-domain death agonist. |  |
| BH3I-1 | ?97% (HPLC), powder, yellow. Group: Fluorescence/luminescence spectroscopy. | |
| BH3I-1 | BH3I-1 is a cell-permeable inhibitor that targets Bcl-2 family protein. It inhibits the binding of BH3 peptides to Bcl-xL and induces apoptosis of Bcl-xL expressing cells. Synonyms: BH3I-1; BH 3I-1; BH-3I-1; BH3I1; BH 3I1; BH-3I1. 2-[(5E)-5-[(4-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-methylbutanoic acid. Grades: 99%. CAS No. 300817-68-9. Molecular formula: C15H14BrNO3S2. Mole weight: 400.31. | |
| BH-9PA | BH-9PA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-(10-Phenylanthracen-9-yl)spiro-[benzo[c]fluorene-7,9'-fluorene]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1262281-88-8. Molecular formula: C49H30. Mole weight: 618.76 g/mol. Product ID: ACM1262281888. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bhopal disaster. | |
| BHA | BHA (Butylated Hydroxy Anisole). CAS No. 25013-16-5. FEMA No. 2183. Kosher: Y. VIGON Item # 500563. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| BHA-polystyrene | BHA-polystyrene. Group: Polystyrene (ps). |  |
| BHHT | BHHT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1'-[1,1':2',1''-Terphenyl]-4,4''-diylbis[4,4,5,5,6,6,6-heptafluoro-1,3-hexanedione. Product Category: Other Fluorophores. CAS No. 200862-69-7. Molecular formula: C30H16F14O4. Mole weight: 706.42. Purity: 95%+. IUPACName: 4,4,5,5,6,6,6-heptafluoro-1-[4-[2-[4-(4,4,5,5,6,6,6-heptafluoro-3-oxohexanoyl)phenyl]phenyl]phenyl]hexane-1,3-dione. Canonical SMILES: C1=CC=C(C(=C1)C2=CC=C(C=C2)C(=O)CC(=O)C(C(C(F)(F)F)(F)F)(F)F)C3=CC=C(C=C3)C(=O)CC(=O)C(C(C(F)(F)F)(F)F)(F)F. Density: 1.453 ± 0.06 g/ml. Product ID: ACM200862697-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bharatiya Janata Party. | |
| Bhimamycin A | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin A has moderate activity against gram-positive and gram-negative bacteria. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Bhimamycin B | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin B has moderate activity against gram-positive and gram-negative bacteria. Molecular formula: C15H10O5. Mole weight: 270.24. | |
| Bhimamycin C | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin C has no antibacterial activity. Molecular formula: C17H17NO5. Mole weight: 315.32. | |
| Bhimamycin D | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin D has no antibacterial activity. Molecular formula: C22H15NO6. Mole weight: 389.36. | |
| Bhimamycin E | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/699. Five components A to E are separated. Bhimamycin E selectively inhibits Staphylococcus aureus. Molecular formula: C13H10O5. Mole weight: 246.21. | |
| BHP | BHP is an antibacterial peptide isolated from Bos taurus. | |
| BHPI | BHPI is an antagonist of estrogen receptor α (ERα), for it elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor. Uses: An antagonist of estrogen receptor α (erα). Synonyms: 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one. Grades: ≥95%. CAS No. 56632-39-4. Molecular formula: C21H17NO3. Mole weight: 331.4. | |
| BHQ | BHQ. Group: Biochemicals. Grades: Purified. CAS No. 88-58-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| BHQ-1-dT | BHQ-1-dT, a widely utilized reagent in the biomedicine realm, remains pertinent for nucleic acid detection and DNA sequencing. Its potential significance surfaces in disease and genetic disorder determination alongside viral load monitoring in infectious cases. From a development standpoint, BHQ-1-dT fosters therapeutic targeting of nucleic acids. Synonyms: 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C74H89N12O14P. Mole weight: 1401.56. | |
| BHQ-2-dT | BHQ-2-dT plays a critical role in propelling PCR probes and hybridization assays to new heights of detection, this modified nucleoside serves as a beacon for identifying viral pathogens, genetic diseases, and cancer biomarkers. With its distinctive fluorescent abilities, molecular matching is taken to the next level of precision and accuracy, boosting sensitivity like never before. Synonyms: 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(4-Nitro-phenyldiazo)-2'-methoxy-5'-methoxy-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 1415097-34-5. Molecular formula: C73H87N12O15P. Mole weight: 1403.53. | |
| BHT | BHT (Butylated Hydroxy Toluene). CAS No. 128-37-0. FEMA No. 2184. Kosher: Y. VIGON Item # 500473. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| B-HT 920 | B-HT 920. Group: Biochemicals. Grades: Purified. CAS No. 36085-73-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| B-HT 920 dihydrochloride | Talipexole is a D2 dopamine receptor agonist, displaying anti-Parkinsonian activity. Uses: A dopamine agonist, also an α2-adrenergic agonist. Synonyms: Talipexole; B-HT 920, B-HT-920, B-HT920, Talipexole HCl, Talipexole dihydrochloride, Domnin6-prop-2-enyl-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-2-amine;dihydrochloride;5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride. Grades: ≥98%. CAS No. 36085-73-1. Molecular formula: C10H15N3S 2HCl. Mole weight: 282.23. | |
| B-HT 920 dihydrochloride talipexole | B-HT 920 dihydrochloride talipexole. Group: Biochemicals. Alternative Names: 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride, 6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine dihydrochloride. Grades: Highly Purified. CAS No. 36085-73-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H17Cl2N3S. US Biological Life Sciences. | Worldwide |
| B-HT 920 Dihydrochloride. Talipexole (5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride) | An alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent. Group: Biochemicals. Alternative Names: 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| B-HT 933 dihydrochloride | B-HT 933 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 36067-72-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| B-HT 933 dihydrochloride | B-HT 933 dihydrochloride is a selective α2-adrenoceptor agonist displaying 300-fold selectivity for the α2-adrenoceptor over the α1-adrenoceptor. B-HT 933 decreases blood pressure and cardiac output in cats, and exhibits antinociceptive activity in mice. Uses: Adrenergic alpha-agonists. Synonyms: B-HT 933 dihydrochloride; B-HT933 dihydrochloride; B-HT-933 dihydrochloride; Azepexole hydrochloride; Azepexole dihydrochloride; 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 36067-72-8. Molecular formula: C9H15N3O.2HCl. Mole weight: 254.16. | |
| B-HT 958 dihydrochloride | B-HT 958 dihydrochloride is a dopamine D2 receptor agonist and an α2-adrenoceptor partial agonist. Synonyms: B-HT 958 dihydrochloride; B-HT958 dihydrochloride; B-HT-958 dihydrochloride; 4H-Thiazolo(4,5-d)azepin-2-amine, 5,6,7,8-tetrahydro-6-((4-chlorophenyl)methyl)-, dihydrochloride; 2-Amino-6-(4-chlorobenzyl)-4,5,7,8-tetrahydro-6H-thiazolo(5,4-d)azepine dihydrochloride; 5,6,7,8-Tetrahydro-6-((4-chlorophenyl)methyl)-4H-thiazolo(4,5-d)azepin-2-amine dihydrochloride. Grades: 99%. CAS No. 36085-44-6. Molecular formula: C14H16ClN3S.2HCl. Mole weight: 366.74. | |
| BHT-A1 | BHT-A1 is produced by Streptococcus rattus BHT. It is active against Gram-positive bacterials. | |
| BHT-B | BHT-B is produced by Streptococcus rattus BHT. BHT-B is a non-modified 5195Da peptide with some similarity to the tryptophan-rich Staphylococcus aureus bacteriocin, aureocin A53. | |
| b-Hydroxytamoxifen (trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-4-ol) | A hydroxylated analogue of tamoxifen with anti-estrogenic properties. Group: Biochemicals. Alternative Names: trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-4-ol. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BI01383298 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BI 01383298 | BI01383298 is a potent and selective inhibitor of human SLC13A5 (Na+/citrate co-transporter) with IC50 of 56 nM in HEK cells overexpressing hSLC13A5. BI01383298 is highly selective over other family members and other transporters with >1000-fold selectivity over others. Synonyms: 1-[(3,5-Dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide. Grades: ≥98%. CAS No. 2227549-00-8. Molecular formula: C19H19Cl2FN2O3S. Mole weight: 445.34. | |
| B I09 | B I09 is a cell permeable IRE-1 RNase inhibitor (IC50 = 1.23 μM) that blocks IRE-1/XBP1 pathway. B I09 exhibits an inhibitory effect on growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model. Uses: Potential treatment of cll. Synonyms: B-I09; B I09; BI09; 7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one. Grades: ≥98% by HPLC. CAS No. 1607803-67-7. Molecular formula: C16H17NO5. Mole weight: 303.31. | |
| BI-167107 | BI-167107 is a β-arrestin-biased D2R agonist that binds to β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM. Synonyms: BI 167107; BI167107. Grades: 98%. CAS No. 1202235-68-4. Molecular formula: C21H26N2O4. Mole weight: 370.4. | |
| BI 224436 | BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC 50 values of less than 15 nM against different HIV-1 laboratory strains. Uses: Scientific research. Group: Signaling pathways. CAS No. 1155419-89-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18595. |  |
| BI 224436 | BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of>90 μM. Synonyms: BI-224436; BI 224436; BI224436. Grades: >98%. CAS No. 1155419-89-8. Molecular formula: C27H26N2O4. Mole weight: 442.51. | |
| Bi 2536 | BI 2536 is a dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respectively. BI-2536 suppresses IFNB (encoding IFN-β) gene transcription. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI 2536;BI-2536, BoehringerPLK-1 inhibitor;4-[[(7R)-8-Cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)benzamide;Benzamide,4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-;Boehringer PLK-1 inhibitor;BI-2536(R-);BI2536/BI-2536;(R)-4-((8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)aMino)-3-Methoxy-N-(1-Methylpiperidin-4-yl)benzaMide. Product Category: Inhibitors. CAS No. 755038-02-9. Molecular formula: C28H39N7O3. Mole weight: 521.662. Purity: 0.9979. Density: 1.28. Product ID: ACM755038029. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-2536 | BI-2563 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division. Synonyms: BI2536; BI 2536. Grades: 0.98. CAS No. 755038-02-9. Molecular formula: C28H39N7O3. Mole weight: 521.65. | |
| BI-2545 | BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC 50 s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2162961-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124772. | |
| BI-2545 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BI-2852 | BI-2852 is a KRAS inhibitor. It blocks the interaction of GEF, GAP and effectors with KRAS, thereby inhibiting downstream signal transduction and producing anti-proliferative effects in KRAS mutant cells. Synonyms: BI-2852; 2375482-51-0; CHEMBL4750445; (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one; (3S)-5-hydroxy-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1H-indol-3-yl]-2,3-dihydroisoindol-1-one; F0K; SCHEMBL24414712; BCP31539; EX-A4793; BDBM50549225; s8959; AKOS040732592; BI2852; BI 2852; MS-29593; HY-126247; CS-0100975; A934943; (S)-5-Hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one; (S)-5-hydroxy-3-(2-(((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methylamino)methyl)-1H-indol-3-yl)isoindolin-1-one. Grades: ≥98% by HPLC. CAS No. 2375482-51-0. Molecular formula: C31H28N6O2. Mole weight: 516.6. | |
| Bi2Te3 Crystal | Bi2Te3 Crystal. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bismuthsesquitelluride;bismuthtelluride(bi2te3);bismuthtelluride,undoped;bismuthtritelluride;tellurobismuthite;tellururedebismuth;BISMUTH TELLURIDE;BISMUTH (III) TELLURIDE. Product Category: Graphene-like Materials Series. CAS No. 1304-82-1. Molecular formula: Bi2Te3. Mole weight: 800.76. Purity: 0.99995. Product ID: ACM1304821. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-3406 | BI-3406 is Potent & Selective SOS1:KRAS Inhibitor (IC50=5 nM), which Opens a New Approach for Treating KRAS-Driven Tumours. BI 3406 selectively binds to SOS1 and blocks the interaction with KRAS, irrespective of the KRAS mutation. BI 3406 causes RAS GTP and pERK reduction and inhibits cell growth of KRAS mutated cell lines, carrying most of the typical KRAS mutations (i.e. G12D, G12V, G13D and others). BI 3406, when administered orally to tumour bearing mice, causes a dose dependent tumour static effect that can be converted into regressions when combined with MEK1 inhibition. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI-3406; BI 3406; BI3406. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2230836-55-0. Molecular formula: C23H25F3N4O3. Mole weight: 462.47. Purity: >98%. IUPACName: N-((R)-1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)-7-methoxy-2-methyl-6-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Canonical SMILES: C[C@H](C1=CC(N)=CC(C(F)(F)F)=C1)NC2=C3C(C=C(OC)C(O[C@H]4CCOC4)=C3)=NC(C)=N2. Product ID: ACM2230836550. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-3406 | BI-3406 is a potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS, and mutants of RAS are major oncogenes and occur in many human cancers. Inhibition of SOS1 in a mutant KRAS cell line can suppress tumor growth. Synonyms: BI 3406; BI3406. CAS No. 2230836-55-0. Molecular formula: C23H25F3N4O3. Mole weight: 462.5. | |
| BI-3802 | BI-3802 is a highly potent BCL6 degrader that inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. It induces BCL6 polymerization and degradation via E3 ligase SIAH1, showing antitumor activity. Grades: ≥98% by HPLC. CAS No. 2166387-65-9. Molecular formula: C24H29ClN6O3. Mole weight: 484.98. | |
| BI-3812 | BI-3812 is potent and efficacious BCL6 inhibitor. It inhibits the BTB domain of BCL6 with an IC50 of ≤3 nM. The high potency and good permeability properties of BI-3812 make this molecule a very good cellular probe compound for testing hypotheses around BCL6 biology. The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Synonyms: BI-3812; 2166387-64-8; CHEMBL4755229; 1-(5-chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide; SCHEMBL20284237; AMY16876; BCP31903; EX-A2841; BDBM50546197; s8735; AKOS040741329; SB40386; BI 3812; BI3812; AC-31571; MS-30157; HY-111381; CS-0040299; A935150; EN300-22885148; Z3417458909; 1-[5-chloro-4-({8-methoxy-1-methyl-3-[(methylcarbamoyl)methoxy]-2-oxo-1,2-dihydroquinolin-6-yl}amino)pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide; 1-[5-Chloro-4-({8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-1,2-dihydro-6-quinolinyl}amino)-2-pyrimidinyl]-N,N-dimethyl-4-piperidinecarboxamide; 1-[5-chloro-4-[[8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxoquinolin-6-yl]amino]pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide. Grades: ≥98%. CAS No. 2166387-64-8. Molecular formula: C26H32ClN7O5. Mole weight: 558.03. | |
| BI-4394 | BI-4394 (MMP13-IN-3) is a potent, selective, and orally active MMP-13 inhibitor ( IC 50=1 nM [1] ) for the potential treatment of osteoarthritis [2]. BI-4394 is >1000 selective over other MMPs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MMP13-IN-3. CAS No. 1222173-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124029. | |
| BI-44847 | BI-44847 is a synthetic bio-active chemical had been in phase II clinical trials for the treatment of type 2 diabetes. Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: BI-44847; BI 44847; BI44847; UNII-43WJ33399D; beta-D-Glucopyranoside,4-((2-fluoro-4-methoxyphenyl)methyl)- 5-methyl-1-(1-methylethyl)-1H-pyrazol-3-yl. Grades: ≥98%. CAS No. 421592-30-5. Molecular formula: C21H29FN2O7. Mole weight: 440.46. | |
| BI-4834 | BI-4834 is a potent and selective Polo-like kinase 1 (PLK1) inhibitor. Synonyms: BI4834; BI 4834. Grades: >98%. CAS No. 876371-13-0. Molecular formula: C21H42N4O3S3. Mole weight: 593.76. | |
| BI 6015 | BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that suppresses expression of known HNF4α target genes. BI 6015 produces cytotoxicity in a range of tumor cell lines, including human hepatocellular carcinoma. Synonyms: BI6015; BI 6015; BI-6015. 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole. Grades: ≥98% by HPLC. CAS No. 93987-29-2. Molecular formula: C15H13N3O4S. Mole weight: 331.35. | |
| BI 6015 | BI 6015. Group: Biochemicals. Grades: Purified. CAS No. 93987-29-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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