A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Comin's reagent. Group: Biochemicals. Grades: Highly Purified. CAS No. 145100-51-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Commendamide
Commendamide is a natural bacterial product which was discovered in a screen for commensal bacteria effector genes (Cbegs). Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM. Synonyms: N-acyl-3-hydroxypalmitoyl-Glycine; 2-(3-hydroxyhexadecanoylamino)acetic acid. Grade: ≥95%. CAS No. 193825-78-4. Molecular formula: C18H35NO4. Mole weight: 329.5.
Commodity Chemicals
Common Chitosan
Common Chitosan. Group: Polymers.
Compel LFRT
Compel LFRT. Group: Polymers.
Competence-Stimulating Peptide-12261
Competence-Stimulating Peptide-12261, is a fragment of Competence-Stimulating Peptide (CSP) composed of 16 amino acids. CSP is a quorum sensing molecule that inhibits the formation of germ tubes (GT). Synonyms: Glu-Ile-Arg-Gln-Thr-His-Asn-Ile-Phe-Phe-Asn-Phe-Phe-Lys-Arg-Arg; CSP-12261. Grade: ≥95%. CAS No. 1235882-91-3. Molecular formula: C100H149N31O23. Mole weight: 2153.45.
Complanatoside A
Complanatoside A. Group: Biochemicals. Alternative Names: Myricetin 3,4?-diglucoside. Grades: Plant Grade. CAS No. 146501-37-3. Pack Sizes: 10mg. Molecular Formula: C27H30O18, Molecular Weight: 642.515999999999. US Biological Life Sciences.
Worldwide
Complanatuside
Complanatuside. Group: Biochemicals. Grades: Plant Grade. CAS No. 116183-66-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Complanatuside
Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati. Uses: Scientific research. Group: Natural products. CAS No. 116183-66-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1444.
Complanatuside 6''-malonate
Complanatuside 6''-malonate. Group: Biochemicals. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Complement C2 deficient serum human
for complement assays. Group: Fluorescence/luminescence spectroscopy.
Complement C3 deficient serum human
substrate serum for C3 activity. Group: Fluorescence/luminescence spectroscopy.
A component of the alternative pathway of complement activation. This reaction is analogous to the activation of complement component C2 by complement subcomponent C1s. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: C3 proactivator convertase; properdin factor D esterase; factor D; factor D (complement). Enzyme Commission Number: EC 3.4.21.46. CAS No. 37213-56-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4139; complement factor D; EC 3.4.21.46; 37213-56-2; C3 proactivator convertase; properdin factor D esterase; factor D; factor D (complement). Cat No: EXWM-4139.
Complement factor D-IN-2, a complement factor D inhibitor, is used in the study of autoimmune diseases. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. (Extracted from patent WO2015130838A1, compound 190). Synonyms: 2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[2-[3-acetyl-5-(2-methyl-5-pyrimidinyl)-1H-indazol-1-yl]acetyl]-N-(6-bromo-2-pyridinyl)-, (1R,3S,5R)-; JYN42346; JYN 42346; JYN-42346. Grade: ≥95%. CAS No. 1903742-34-6. Molecular formula: C27H24BrN7O3. Mole weight: 574.43.
Activated from proenzyme C1r in plasma during activation of the complement system by the "classical" route. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: activated complement C1r; C1r esterase; activated complement C1r. Enzyme Commission Number: EC 3.4.21.41. CAS No. 80295-69-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4135; complement subcomponent C1r; EC 3.4.21.41; 80295-69-8; activated complement C1r; C1r esterase; activated complement C1r. Cat No: EXWM-4135.
complement subcomponent C1s
Activated from proenzyme C1s in plasma by complement subcomponent C1r. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: C1 esterase; activated complement C1s; complement C1r. Enzyme Commission Number: EC 3.4.21.42. CAS No. 80295-70-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4136; complement subcomponent C1s; EC 3.4.21.42; 80295-70-1; C1 esterase; activated complement C1s; complement C1r. Cat No: EXWM-4136.
Complete Freund's adjuvant (CFA)
Complete Freund's adjuvant (CFA) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund to enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA) stimulates a strong and durable immune response and can be used to induce persistent inflammatory pain models in mice, experimental autoimmune myocarditis (EAM) models, and more. Incomplete Freund's adjuvant (IFA) (HY-153808A) is another type of Freund's Adjuvant that stimulates a weaker immune response[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9007-81-2. Pack Sizes: 10 mL; 10 mL * 2; 10 mL * 5. Product ID: HY-153808.
Completely Denatured Alcohol CDA 12A 275 TOTE
275 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A 330 TOTE
330 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A BULK
Tanker volume. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A DRUM
55 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A GALLON
1 gallon of product. Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A GALLON CASE
4 gallons of product (4 bottles). Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A PALE
5 gallons of product. Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Complex Mixture of PAHs from Coal Tar
Complex Mixture of PAHs from Coal Tar. Uses: For analytical and research use. Group: Polycyclic aromatic hydrocarbons (pahs). Catalog: APS006929. Shipping: Room Temperature.
Complex Nutrients - WP
Proficiency Testing Material. Group: Waste water.
Complex of α-D-Glucopyranosyl isomaltol 85% and α-D-Maltosyl isomaltol 15%
Complex of α-D-Glucopyranosyl isomaltol 85% and α-D-Maltosyl isomaltol 15%. Synonyms: Active hexose correlated compound; Complex of 1-[3-(α-D-Glucopyranosyloxy)-2-furanyl]-ethanone 85% and 1-[3-(4-O-α-D-Glucopyranosyl-α-D-glucopyranosyloxy)-2-furanyl]-ethanone 15%. Grade: ≥97%. Molecular formula: C12H16O8.C18H26O13. Mole weight: 450.39/288.25.
Compound 10
Compound 10 is a tool compound targeting the NFAT:AP-1 transcriptional complex on DNA. Synonyms: 2-(5-(1H-Benzo[d]imidazol-2-yl)pyridin-2-ylthio)-N-(3-acetamidophenyl)acetamide. Grade: 99%. CAS No. 841210-82-0. Molecular formula: C22H19N5O2S. Mole weight: 417.48.
Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Compound 120
Compound 120 is a partially deuterated analogue of Atazanavir, which is an oral HIV protease inhibitor. Compound 120 increases half life by approximately 50% in comparison with Atazanavir. Synonyms: Atazanavir-d15 sulfate. Grade: 99%. Molecular formula: C38H37D15N6O7.H2O4S. Mole weight: 818.03.
Compound 1T-0216
Compound 1T-0216 is a blocker of AKT1-FAK interaction, reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation. Synonyms: 1-(2-{[(2-methylbenzoyl)oxy]imino}cyclohexyl)-2,4-dinitrobenzene; [(1E)-2-(2,4-dinitrophenyl)cyclohexylidene]amino 2-methylbenzoate. CAS No. 383147-88-4. Molecular formula: C20H19N3O6. Mole weight: 397.39.
Compound 1T-0219 (SC)
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction which reduces the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation. Synonyms: [(1E)-2-(2,4-dinitrophenyl)cyclohexylidene]amino 4-methoxybenzoate; N-[2-(2,4-dinitrophenyl)cyclohexyliden]-N-[(4-methoxybenzoyl)oxy]amine; ZINC4085554. CAS No. 383147-92-0. Molecular formula: C20H19N3O7. Mole weight: 413.37.
Compound 3344 hydrochloride
Compound 3344 hydrochloride is an inhibitor of KRAS-effector interaction with an affinity of 126 nm. Synonyms: 4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-N-(3-((dimethylamino)methyl)phenyl)-2-methoxyaniline hydrochloride; Benzenemethanamine, 3-[[4-(2,3-dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethyl-, hydrochloride (1:1); 3-[[4-(2,3-Dihydro-1,4-benzodioxin-5-yl)-2-methoxyphenyl]amino]-N,N-dimethylbenzenemethanamine hydrochloride; [4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)-2-methoxyphenyl][3-[(dimethylamino)methyl]phenyl]amine hydrochloride. Grade: ≥95%. CAS No. 2760889-75-4. Molecular formula: C24H26N2O3.HCl. Mole weight: 426.94.
Compound 34
Cell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06nM). Group: Biochemicals. Alternative Names: (2S,3R)-3-(3,4-Difluorophenyl)-2-(4-fluorophenyl)-4-hydroxy-N-((3S)-2-oxo-5-phenyl-2,3-1H-benzodiazepin-3-yl)butyramide. Grades: Highly Purified. CAS No. 564462-36-8. Pack Sizes: 200ug, 1mg. Molecular Formula: C31H24F3N3O3. US Biological Life Sciences.
Worldwide
Compound 401
Compound 401. Group: Biochemicals. Grades: Purified. CAS No. 168425-64-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Compound 401
Compound 401, a pyrimido-isoquinolinone compound, is a selective and cell-permeable inhibitor that has an reversible function on DNA-dependent protein kinase (DNA-PK). It is also a mammalian target of rapamycin (mTOR) with little affinity for 43 other com. Synonyms: 2-morpholin-4-ylpyrimido[2,1-a]isoquinolin-4-oneCompound 401; Compound-401; Compound401; 168425-64-72-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-oneCHEMBL1792422-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-oneSCHEMBL10092321CTK4D2994S-7713; S 7713; S77132-(morpholin-4-yl)pyrimido[2,1-a]iso. Grade: >99 %. CAS No. 168425-64-7. Molecular formula: C16H15N3O2. Mole weight: 281.31.
Compound 401
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 168425-64-7. Molecular formula: C16H15N3O2. Purity: >99 %. Product ID: ACM168425647. Alfa Chemistry ISO 9001:2015 Certified.
Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC?? = 0.28uM) that also targets mTOR (IC50 = 5. 3uM), but not PI 3-K in vitro. Induces apoptosis in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 168425-64-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Compound 401 - CAS 168425-64-7
A cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC?? = 280 nM) with ~19-fold selectivity over mTOR (IC?? = 5.3 μM). Group: Fluorescence/luminescence spectroscopy.
Compound 43 TAO Kinase Inhibitor
Compound 43 TAO kinase inhibitor is an ATP-competitive and selective inhibitor of TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Synonyms: N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide. Grade: ≥98%. CAS No. 850467-66-2. Molecular formula: C25H24N2O2. Mole weight: 384.47.
Compound 48/80
Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Poly-p-methoxyphenethylmethylamine. CAS No. 94724-12-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-115768.
Compound 48/80 hydrochloride
Compound 48/80 is a condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde that causes histamine degranulation from mast cells. Compound 48/80 also inhibits human platelet aggregation through suppression of calmodulin (CaM) (IC50 = 0.41 μg/ml for CaM-dependent Ca2+-transporter ATPase activity) and phospholipase C. Synonyms: 4-methoxy-3,5-bis[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-N-methyl-benzeneethanamine trihydrochloride. Grade: ≥95%. CAS No. 848035-21-2. Molecular formula: C32H45N3O3·3HCl. Mole weight: 629.1.
Compound 56
Compound 56 is a highly potent inhibitor of the epidermal growth factor receptor (EGFR; IC50 = 0.006 nM). It has been used to inhibit EGFR activity in pancreatic cancer cell lines and it can induce the differentiation of rat mesenchymal stem cells. Synonyms: N-(3-bromophenyl)-6,7-diethoxy-4-quinazolinamine. Grade: ≥95%. CAS No. 171745-13-4. Molecular formula: C18H18BrN3O2. Mole weight: 388.3.
Compound 56 - CAS 171745-13-4
A cell-permeable, reversible, ATP-competitive, highly potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (IC?? = 6 pM). Group: Fluorescence/luminescence spectroscopy.
Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC 50 s of 0.24, 0.37, 0.32 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Secretase-IN-1. CAS No. 209986-17-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14176.
Compound E
Cell permeable, potent, selective, non-transition state and non-competitive gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity. Group: Biochemicals. Alternative Names: (2S)-2-(amino)-N-propanamide. Grades: Highly Purified. CAS No. 209986-17-4. Pack Sizes: 250ug, 1mg, 5mg. Molecular Formula: C27H24F2N4O3. US Biological Life Sciences.
Worldwide
Compound E
Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM). Synonyms: γ-Secretase Inhibitor; Gamma-Secretase Inhibitor XXI; (S,S)- 2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide; (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide; N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide. Grade: 98%. CAS No. 209986-17-4. Molecular formula: C27H24F2N4O3. Mole weight: 490.5.