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Cycloserine diketopiperazine. Group: Biochemicals. Alternative Names: 3,6-Bis[(aminooxy)methyl]-2,5-piperazinedione; 2, 5-Bis (aminohydroxymethyl)-2, 6-diketopiperazine; 2,5-Bis(aminooxymethyl)-3,6-dioxopiperazine. Grades: Highly Purified. CAS No. 1204-99-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C6H12N4O4. US Biological Life Sciences.
Worldwide
Cycloserine Diketopiperazine
Cycloserine Diketopiperazine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,6-Bis[(aminooxy)methyl]-2,5-piperazinedione; 2,5-Bis(aminohydroxymethyl)-2,6- diketopiperazine. Product Category: Heterocyclic Organic Compound. CAS No. 1204-99-5. Molecular formula: C6H12N4O4. Mole weight: 204.18. Product ID: ACM1204995-1. Alfa Chemistry ISO 9001:2015 Certified.
Cycloserine Diketopiperazine
Cycloserine Diketopiperazine is a Cycloserine dimer as potential impurity of drug Cycloserine. Synonyms: 3,6-Bis[(aminooxy)methyl]-2,5-piperazinedione; 2,5-Bis(aminohydroxymethyl)-2,6- diketopiperazine; 2,5-Bis(aminooxymethyl)-3,6-dioxopiperazine; Cycloserine Diketopiperazine; NSC 119130. Grade: > 95%. CAS No. 1204-99-5. Molecular formula: C6H12N4O4. Mole weight: 204.18.
Cycloserine Impurity 1
D-Serine is a proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. It is a inhibitor of serine palmitoyltransferase. It is also a neuromodulator. Synonyms: D-Serine; (R)-2-Amino-3-hydroxypropanoic Acid; (R)-2-Amino-3-hydroxypropanoic Acid; (R)-Serine; NSC 77689. Grade: ≥ 99% (Titration: anhydrous basis). CAS No. 312-84-5. Molecular formula: C3H7NO3. Mole weight: 105.09.
Cycloserine Impurity 2
Cycloserine Impurity 2 is a derivative of Cycloserine, renowned for its remarkable efficacy in treating tuberculosand sundry bacterial afflictions. Synonyms: D-Serine Methyl Ester Hydrochloride; (R)-2-Amino-3-hydroxypropionic Acid Methyl Ester Hydrochloride; (R)-Methyl 2-Amino-3-hydroxypropanoate Hydrochloride; Methyl D-Serinate Hydrochloride. Grade: ≥ 98% (HPLC). CAS No. 5874-57-7. Molecular formula: C4H10ClNO3. Mole weight: 155.58.
Cycloserine Impurity 3
Cycloserine Impurity 3 is an impurity of Cycloserine, a medication for treating tuberculosand sundry bacterial afflictions. Synonyms: 3-chloro-D-alanine methyl ester hydrochloride; 3-Chloro-D-Ala-OMe hydrochloride; β-Chloro-D-alanine methyl ester hydrochloride; (S)-Methyl 2-amino-3-chloropropanoate hydrochloride; (S)-Methyl 2-amino-3-chloropropionate hydrochloride. Grade: > 95%. CAS No. 112346-82-4. Molecular formula: C4H9Cl2NO2. Mole weight: 174.03.
Cycloserine Impurity 5
3,6-Methylene-2,5-piperazinedione is an impurity of Cycloserine, an antibacterial agent. Synonyms: 3,6-Methylene-2,5-piperazinedione; 3,6-Bis(methylene)-2,5-piperazinedione; 2,5-Dimethylene-3,6-diketopiperazine; 3,6-Dimethylene-2,5-piperazinedione; NSC 278175. Grade: > 95%. CAS No. 15996-22-2. Molecular formula: C6H6N2O2. Mole weight: 138.12.
Cycloserine Impurity 8
Cycloserine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102439-46-3. Molecular formula: C9H12O3S. Mole weight: 200.25. Catalog: APB102439463.
Cycloserine Impurity 9 (Hydrochloride)
Cycloserine Impurity 9 (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-amino-3-methoxypropanamide hydrochloride. CAS No. 15102-46-2. Molecular formula: C4H10N2O2·HCl. Mole weight: 154.59. Catalog: APB15102462.
Cyclosomatostatin
Cyclosomatostatin is a non-selective somatostatin (sst) receptor antagonist. It blocks the effects of CRF-induced suppression of gastric empyting and sst on airway β-adrenergic function. It also prevents growth hormone, insulin, glucagon release and modulation of ACh release. It acts as a sst receptor agonist in human neuroblastoma cell line SH-SY5Y. Uses: Hormone antagonists. Synonyms: Cyclo(7-aminoheptanonyl-Phe-D-Trp-Lys-Thr[Bzl]); Cyclo[7-aminoheptanoyl-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-threonyl]. CAS No. 84211-54-1. Molecular formula: C44H57N7O6. Mole weight: 779.98.
Cyclosomatostatin
Cyclosomatostatin. Group: Biochemicals. Grades: Purified. CAS No. 84211-54-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosomatostatin acetate
Cyclosomatostatin acetate is an effective antagonist of the somatostatin receptor. Cyclosomatostatin acetate inhibits SSTR1 signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in colorectal cancer cells. Synonyms: 1,4,7,10,13-Pentaazacycloeicosane-2,5,8,11,14-pentone, 6-(4-aminobutyl)-9-(1H-indol-3-ylmethyl)-3-[(1R)-1-(phenylmethoxy)ethyl]-12-(phenylmethyl)-, acetate (1:1), (3S,6S,9R,12S)-; Cyclo[7-aminoheptanoyl-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-threonyl], monoacetate; Cyclo-Somatostatin acetate. Grade: ≥95%. CAS No. 211056-95-0. Molecular formula: C44H57N7O6.C2H4O2. Mole weight: 840.02.
Cyclosomatostatin TFA
Cyclosomatostatin TFA can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, which is a potent somatostatin (SST) receptor antagonist. Synonyms: Cyclosomatostatin (TFA). Molecular formula: C46H58F3N7O8. Mole weight: 893.99.
Cyclosonide impurity 2
Cyclosonide impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1005416-98-7. Molecular formula: C35H48O7. Mole weight: 580.76. Catalog: APB1005416987.
Cyclosonide impurity 4
Cyclosonide impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1333428-69-5. Molecular formula: C7HD11O. Mole weight: 123.24. Catalog: APB1333428695.
Cyclosporin
It is produced by the strain of Polypocladiurn inflatum. It has a strong immunosuppressive action, but also has anti-inflammatory and weak antifungal effects. The mechanism of immunosuppression is the combination of cyclosporin A and cyclosporin-binding protein in T cells, which inhibits the activity of Calcineurin, and then impedes the transposition of intracellular transcription factors into the nucleus, and inhibits the interleukin-2 transcription, resulting in immunosuppression. It is mainly used for kidney transplantation, bone marrow and heart transplantation, and is one of the most important immunosuppressive agents in clinical application. Uses: Enzyme inhibitors. Synonyms: Cyclosporins. Grade: >98%. CAS No. 79217-60-0.
Cyclosporin
Cyclosporin is a cyclic decapeptide that could be isolated form the soil fungi Tolypocladium inflatum. Cyclosporin is an immunosuppressant thought to bind to cyclophilin in T-lymphocytes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79217-60-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-100731.
Cyclosporin A
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C62H111N11O12. CAS No. 59865-13-3. Prepack ID 40007313-1g. Molecular Weight 1202.61. See USA prepack pricing.
Cyclosporin A
Cyclosporin A (Cyclosporine A) is an immunosuppressant that binds to cyclophilins, inhibiting calcineurin activity with an IC50 of 7 nM. It also inhibits CD11a/CD18 adhesion molecules. Synonyms: Ciclosporin; cyclosporine; Cyclosporine A; Sandimmun; Cyclosporin; Neoral; Ciclosporine; Sandimmune; Ramihyphin A. Grade: 98%. CAS No. 59865-13-3. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Cyclosporin A
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C62H111N11O12. CAS No. 59865-13-3. Prepack ID 40007313-100mg. Molecular Weight 1202.61. See USA prepack pricing.
Cyclosporin A
Potent immunosuppressant (same as FK-506 and rapamycin). Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phos- phatase 2B (PP2B; calcineurin). Prevents the dephosphorylation of nuclear factor of activated T cells (NFAT) transcription factor, leading to disruption of T cell activation. Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Antibacterial. Antifungal. Antiparasitic. Apoptosis inhibitor. Inhibits the mitochondrial permeability transition pore (MPTP) from opening, thus inhibiting cytochrome c release. NF-kappaB suppressor by induction of unfolded protein response (UPR). Anti-cancer compound. Apoptosis and autophagy inducer. Inhibits n Group: Biochemicals. Alternative Names: Antibiotic S 7481F1; Ciclosporin A; CsA; Cyclosporine; NSC 290193; Ramihyphin A; Sandimmun; Sandimmune; Neoral; Optimmune; Restasis; OL 27-400. Grades: Highly Purified. CAS No. 59865-13-3. Pack Sizes: 5g, 10g. US Biological Life Sciences.
Worldwide
Cyclosporin A
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM[3]. Cyclosporin A also inhibits CD11a/CD18 adhesion[8]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyclosporine A; Ciclosporin A; CsA. CAS No. 59865-13-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0579.
Cyclosporin A-13C2,d4 Acetate
Labeled Cyclosporin A derivative. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity. Group: Biochemicals. Alternative Names: Cyclosporine-13C2,d4 Acetate; Ciclosporin-13C2,d4 Acetate; Atopica-13C2,d4 Acetate; Sandimmun(e)-13C2,d4 Acetate; Neoral-13C2,d4 Acetate; Optimmune-13C2,d4 Acetate; Restasis-13C2,d4 Acetate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-13C2,d4 (Major).
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Cyclosporine-13C2,d4; Ciclosporin-13C2,d4; Atopica-13C2,d4; Sandimmun(e)-13C2,d4; Neoral-13C2,d4; Optimmune-13C2,d4; Restasis-13C2,d4. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Cyclosporin A 8-N-MeAla
Cyclosporin A 8-N-MeAla. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108466-41-7. Molecular formula: C63H113N11O12. Mole weight: 1216.66. Catalog: APB108466417.
Cyclosporin A, 9-(4-hydroxy-N-methyl-L-leucine)-
Cyclosporin A, 9-(4-hydroxy-N-methyl-L-leucine)- is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin Impurity 19. CAS No. 107335-26-2. Molecular formula: C62H111N11O13. Mole weight: 1218.63.
Cyclosporin A Acetate
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic acid] Cyclosporin A; B 3-243; O-Acetyl-C91-cyclosporin A; O-Acetylcyclosporin A; SDZ 33-243. Grades: Highly Purified. CAS No. 83602-41-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-[d4]
Cyclosporin A-[d4], is the labelled analogue of Cyclosporin A. Ciclosporin is believed to work by decreasing the function of lymphocytes. It is taken by mouth or by injection into a vein for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, and in organ transplants to prevent rejection. Synonyms: Cyclosporine-d4; Ciclosporin-d4; Atopica-d4; Cyclosporin A D4. Grade: 95% by HPLC; 95% atom D. Molecular formula: C62H107D4N11O12. Mole weight: 1206.64.
Cyclosporin A-[d4] Acetate
Cyclosporin A-[d4] Acetate is a labelled analogue of Cyclosporin A. Ciclosporin is an immunosuppressant medication. Synonyms: Cyclosporin A-D4 Acetate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C64H109D4N11O13. Mole weight: 1248.67.
Cyclosporin A-d4 Acetate (Major)
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic-d4 acid] Cyclosporin A; B 3-243-d4; O-Acetyl-C91-cyclosporin A-d4; O-Acetylcyclosporin A-d4; SDZ 33-243-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-d4 (Major)
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Cyclosporine-d4; Ciclosporin-d4; Atopica-d4; Sandimmun(e)-d4; Neoral-d4; Optimmune-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-Derivative 1
Cyclosporin A-Derivative 1 is a metabolite of cyclosporine A. Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin phosphatase. Synonyms: Leu-Val-Leu-Ala-D-Ala-Leu-Leu-Val-Aaa-Abu-Sar.BF4; (7S,10S,13S,16S,19S,22R,25S,28S,31S,34S)-10-[(1R,2R,4E)-1-Acetoxy-2-methyl-4-hexen-1-yl]-7-ethyl-16,19,28-triisobutyl-13,31-diisopropyl-N,5,11,14,17,20,22,25,29,36-decamethyl-3,6,9,12,15,18,21,24,27,3 0,33-undecaoxo-2-oxa-5,8,11,14,17,20,23,26,29,32-decaazaheptatriacontan-34-aminium tetrafluoroborate. Grade: ≥98%. CAS No. 1487360-85-9. Molecular formula: C65H118BF4N11O14. Mole weight: 1364.50.
Cyclosporin A-Derivative 1 Free base
Cyclosporin A-Derivative 1 Free base is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A open ring; N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Cyclosporin A-Derivative 1 (Free base); Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar}; LVLA-{d-Ala}-LLV-{Aaa}-{Abu}-{Sar}. Grade: ≥95%. CAS No. 286852-20-8. Molecular formula: C65H117N11O14. Mole weight: 1276.69.
Cyclosporin A-Derivative 2
Cyclosporin A-Derivative 2 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: L-Valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester; Des(N-Methyl-leucyl) Cyclosporin A seco(MeGly-MeLeu) Methyl Ester; Glycine, L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester. Grade: ≥95%. CAS No. 156047-45-9. Molecular formula: C58H104N10O13. Mole weight: 1149.51.
Cyclosporin AM 1
A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite 17; Cyclosporin Metabolite 17; M 17; OL 17. Grades: Highly Purified. CAS No. 89270-28-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin AM 3
Cyclosporin AM 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153049-50-4. Molecular formula: C62H111N11O13. Mole weight: 1218.63. Catalog: APB153049504.
Cyclosporin AM 4N
Cyclosporin AM 4N is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 9-L-Leucinecyclosporin A; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv; AM 4N; Cyclosporin A Metabolite 21; M 21; OL 21; [Leu4]cyclosporin. Grade: ≥90% by HPLC. CAS No. 89270-23-5. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin AM 4N Acetate
Cyclosporin AM 4N Acetate is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: O-Acetyl-9-L-leucinecyclosporin A; O-Acetyl-cyclosporin A Metabolite 21. Grade: ≥95%. Molecular formula: C63H111N11O13. Mole weight: 1230.62.
Cyclosporin AM 7
Cyclosporin AM 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132362-39-1. Molecular formula: C61H109N11O13. Mole weight: 1204.61. Catalog: APB132362391.
Cyclosporin AM 9
Cyclosporin AM 9 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (4-Hydroxy-N-methyl-L-leucine)cyclosporine; 3-(4-Hydroxy-N-methyl-L-leucine)cyclosporin A; Cyclosporin A Metabolite 1; AM 9 (Peptide); OL 1; Cyclosporine metabolite M1; Cyclosporin metabolite AM9; Cyclosporine metabolite AM9; Cyclosporin A metabolite M1; (gamma-OH)MeLeu-9-cyclosporin; (gamma-OH)MeLeu-9-cyclosporine; (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-4-hydroxy-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-). Grade: ≥90% by HPLC. CAS No. 89270-25-7. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporin A, Ready Made Solution
1 mg/mL in DMSO (0.2 ?m-filtered). Group: Fluorescence/luminescence spectroscopy.
Cyclosporin A solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
Cyclosporin A solution
100 ?g/mL in acetonitrile, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
Cyclosporin A (Standard)
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM [3]. Cyclosporin A also inhibits CD11a/CD18 adhesion [8]. Uses: Scientific research. Group: Natural products. CAS No. 59865-13-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0579R.
Cyclosporin a sulfate
Cyclosporin a sulfate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cyclosporin A Hydrogen Sulfate (ester). Product Category: Heterocyclic Organic Compound. CAS No. 121673-00-5. Molecular formula: C62H111N11O15S. Mole weight: 1282.67. Purity: 0.96. Product ID: ACM121673005. Alfa Chemistry ISO 9001:2015 Certified.
Cyclosporin A sulfate
Cyclosporin A sulfate. Group: Biochemicals. Alternative Names: Cyclosporin A hydrogen sulfate (ester). Grades: Highly Purified. CAS No. 121673-00-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C62H111N11O15S. US Biological Life Sciences.
Worldwide
Cyclosporin A Sulfate
Cyclosporin A Sulfate is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A metabolite of cyclosporin a. Synonyms: Cyclosporin A Hydrogen Sulfate (ester); Cyclosporine Sulfate; (1R,2R,4E)-1-[(2S,5S,11S,14S,17S,20S,23R,26S,29S,32S)-5-Ethyl-11,17,26,29-tetraisobutyl-14,32-diisopropyl-1,7,10,16,20,23,25,28,31-nonamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl]-2-methyl-4-hexen-1-yl hydrogen sulfate. Grade: 95%. CAS No. 121673-00-5. Molecular formula: C62H111N11O15S. Mole weight: 1282.67.
Cyclosporin B
Cyclosporin B is a group of nonpolar cyclic oligopeptides with immunosuppressive activity. Cyclosporin B is used for the prevention of graft rejection in organ transplantation [1]. Uses: Scientific research. Group: Peptides. CAS No. 63775-95-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1973.
Cyclosporin B
Cyclosporin B is a minor analogue of the cyclosporin complex produced by Trichoderma. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Synonyms: 7-L-Alaninecyclosporine A. Grade: ≥90% by HPLC. CAS No. 63775-95-1. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin B
An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Group: Biochemicals. Alternative Names: Ala2-cyclosporine; Antibiotic S 7481F2. Grades: Highly Purified. CAS No. 63775-95-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin C
A group of nonpolar cyclic oligopeptides with immunosupppressant activity. Group: Biochemicals. Alternative Names: Thr2-cyclosporine. Grades: Highly Purified. CAS No. 59787-61-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cyclosporin C
A minor analogue of the cyclosporin complex produced by a number of fungal species, including trichoderma, tolypocladium, fusarium, nectria and acremonium. It has the immunosuppressant activity but has been much less extensively investigated than the major analogue, cyclosporin A. Cyclosporin C is a broad-spectrum antifungal agent against filamentous phytopathogenic fungi but no activity against bacteria or yeasts. Synonyms: 7-L-Threoninecyclosporin A; WF 3484. Grade: ≥90% by HPLC. CAS No. 59787-61-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporin C
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal , antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea , A. niger , and Alternaria , Mucor , and Penicillium species (MICs=0.1-5 μg/ml). Uses: Scientific research. Group: Signaling pathways. CAS No. 59787-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6027.
Cyclosporin C
?95% (HPLC), from Acremonium luzulae. Group: Fluorescence/luminescence spectroscopypharmaceutical toxicology. Alternative Names: 7-L-Threonine-cyclosporin A, Cyclosporin C, Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-threonyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl], 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.,Ciclosporin C.
Cyclosporin d
Cyclosporin d. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CYCLOSPORIN D;Val2-cyclosporine;(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];7-L-Valinecyclosporin A;Cyclosporine IMpurity-D;7-L-valinecyclosporine A. Product Category: Heterocyclic Organic Compound. CAS No. 63775-96-2. Molecular formula: C63H111N11O12. Mole weight: 1214.62. Product ID: ACM63775962. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cyclosporin (disambiguation).
Cyclosporin D
Cyclosporin D is a group of nonpolar cyclic oligopeptides with immunosupppressant activity. Cyclosporin D is a minor analogue of the cyclosporin complex produced by Trichoderma. Synonyms: Ciclosporin Impurity G; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]; [Val7]ciclosporin A; Ciclosporin D; Val2-cyclosporine; 7-L-Valinecyclosporin A; Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]; Cyclosporine D; cyclo[Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)-Val-Sar-N(Me)Leu-Val-N(Me)Leu]. Grade: ≥90% by HPLC. CAS No. 63775-96-2. Molecular formula: C63H113N11O12. Mole weight: 1216.64.
Cyclosporin D
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A [1] [2]. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) [3]. Uses: Scientific research. Group: Peptides. CAS No. 63775-96-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W019721.
Cyclosporin D solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
The pharmacological profiles of two new derivatives of the immunosuppressive drug, cyclosporine, is presented here. (Nva2)-CS has very similar properties to CS, but lacks the nephrotoxic side-effects. This derivative appears to be a potential successor to cyclosporine. (Val2)DH-CS seems to have a different spectrum of activities. It does not suppress humoral immunity and allograft rejection, but suppresses some types of cell-mediated immune responses. This derivative may prove useful in autoimmune situations where T cells are involved in the disease process. Group: Biochemicals. Alternative Names: Val2-cyclosporine, Cyclosporin D, Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl. Grades: Highly Purified. CAS No. 63775-96-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C63H113N11O12, Molecular Weight: 1216.64. US Biological Life Sciences.
Worldwide
Cyclosporine
Cyclosporine is an immunopsupressent thought to bind to cyclophilin in T-lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 79217-60-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C62H111N11O12, Molecular Weight: 1202.60999999999. US Biological Life Sciences.
Worldwide
Cyclosporin E
Cyclosporin E is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: Cyclosporin A, 5-L-valine-; Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl); 5-L-Valinecyclosporin A; (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-L-Val-). Grade: ≥90% by HPLC. CAS No. 63798-73-2. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporine A
Cyclosporine A. CAS No: 59865-13-3
Sarchem Laboratories New Jersey NJ
Cyclosporine B
Cyclosporine B. Group: Biochemicals. Alternative Names: Cyclosporin B, Ala2-cyclosporine, Antibiotic S 7481F2. Grades: Highly Purified. CAS No. 63775-95-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C61H109N11O12. US Biological Life Sciences.
Worldwide
Cyclosporine C
Cyclosporine C. Group: Biochemicals. Alternative Names: Cyclosporin C, Thr2-cyclosporine. Grades: Highly Purified. CAS No. 59787-61-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C62H111N11O13. US Biological Life Sciences.
Worldwide
Cyclosporine Impurity 1
Cyclosporine Impurity 1 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (4S,5R)-5-((R,E)-hex-4-en-2-yl)-3-methyl-2-oxo-N-((4S,7S,10R,13S,16S,19S,22S,28S)-4,7,16,22-tetraisobutyl-19-isopropyl-8,10,13,17,23,26-hexamethyl-3,6,9,12,15,18,21,24,27-nonaoxo-2,5,8,11,14,17,20,23,26-nonaazatriacontan-28-yl)oxazolidine-4-carboxamide. Grade: ≥95%. Molecular formula: C57H101N11O12. Mole weight: 1132.50.
Cyclosporine Impurity 3 Sodium Salt
Cyclosporine Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥90% by HPLC. Molecular formula: C7H14NO3Na. Mole weight: 183.18.
Cyclosporine metabolite M17
Cyclosporine metabolite M17 is a metabolite of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Synonyms: Cyclosporin AM 1; 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite M17; Cyclosporin metabolite AM1; OL-17; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 33-[(1R,2R,4E)-1,6-dihydroxy-2-methyl-4-hexen-1-yl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-. Grade: ≥90% by HPLC. CAS No. 89270-28-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporine Resolution Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Cyclosporine Resolution Mixture
This material is an approximate 100:1 (w/w) mixture of cyclosporine and cyclosporine U (USP).