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| Product | Description | |
|---|---|---|
| CA-074 methyl ester | CA-074 Me is a membrane-permeable inhibitor of irreversible cathepsin B derived from CA-074. CA-074 Me would be hydrolyzed by intracellular esterases to CA-074, the active compound. Synonyms: Ca-074Me; Ca 074Me; Ca074Me; Cathepsin B Inhibitor IV; MFCD03452890; (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine-2-carboxylate; CA-074 Me. Grade: 99.04 %. CAS No. 147859-80-1. Molecular formula: C19H31N3O6. Mole weight: 397.47. |  |
| CA-074 methyl ester | CA-074 methyl ester is a specific inhibitor of Cathepsin B , which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CA-074Me. CAS No. 147859-80-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100350. |  |
| CA 074 (N-[[(2S,3S)-3-[(Propylamino)carbony l]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline) | Inhibitor of cathepsin B (Ki = 2-5nm). Displays selectivity over cathepsins H and L (Ki = 40-200um). Shown to reduce bone metastasis in a 4T1.2 breast cancer model. Group: Biochemicals. Grades: Highly Purified. CAS No. 134448-10-5. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| CA-170 | CA-170 is an orally delivered dual inhibitor of VISTA and PD-L1. CA-170 exhibits potent rescue of proliferation and effector functions of T cells inhibited by PD-L1/L2 and VISTA with selectivity over other immune checkpoint proteins as well as a broad panel of receptors and enzymes[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1673534-76-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101093. | |
| CA224 | CA224 (Compound 1) is a selective and orally active Cdk4 - cyclin D1 inhibitor with an IC 50 of 6.2 μM. CA224 induces cell apoptosis and shows antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 883561-04-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-111207. | |
| c[A(2',5')pA(2',5')p] | c[A(2',5')pA(2',5')p] is a cyclic dinucleotide analogue of c-diAMP, the bacterial second messenger. Synonyms: Cyclic (adenosine- (2' -≥ 5')- monophosphate- adenosine- (2' -≥ 5')- monophosphate), sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H24N10O12P2. Mole weight: 658.4. | |
| c[A(2',5')pS[Sp]-A(3',5')pS[Rp]] | c[A(2',5')pS[Sp]-A(3',5')pS[Rp]] is asyntheticdi-thiophosphate analogue of c[A(2',5')pA(3',5')p] with higher stability resisting degradation by phosphodiesterases. Grade: ≥ 95% by HPLC. CAS No. 1638242-31-5. Molecular formula: C20H24N10O10P2S2 (free acid). Mole weight: 690.6 (free acid). | |
| Ca2+/calmodulin-dependent protein kinase | Requires calmodulin and Ca2+ for activity. A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light chains and the microtubule-associated tau protein. Not identical with EC 2.7.11.18 (myosin-light-chain kinase) or EC 2.7.11.26 (tau-protein kinase). Group: Enzymes. Synonyms: ATP:caldesmon O-phosphotransferase; caldesmon kinase; caldesmon kinase (phosphorylating); Ca2+/calmodulin-dependent microtubule-associated pro. Enzyme Commission Number: EC 2.7.11.17. CAS No. 141467-21-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3136; Ca2+/calmodulin-dependent protein kinase; EC 2.7.11.17; 141467-21-2; ATP:caldesmon O-phosphotransferase; caldesmon kinase; caldesmon kinase (phosphorylating); Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase; Ca2+/calmodulin-dependent protein kinase 1; Ca2+/calmodulin-dependent protein kinase II; Ca2+/calmodulin-dependent protein kinase IV; Ca2+/calmodulin-dependent protein kinase kinase; Ca2+/calmodulin-dependent protein kinase kinase β; calmodulin-dependent kinase II; CaM kinase; CaM kinase II; CAM PKII; CaM-regulated serine/threonine kinase; CaMKI; CaMKII; CaMKIV; CaMKKα; CaMKKβ; microtubule-associated protein 2 kinase; STK20. Cat No: EXWM-3136. |  |
| Ca2+/Calmodulin Kinase II Inhibitor 281-309 | The Ca2+/Calmodulin Kinase II Inhibitor 281-309 controls the biological activity of Ca2+/Calmodulin Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. |  |
| Ca2+ Channel Agonist 1 | A Ca2+ Channel Agonist that selectively acting on N-type Ca2+ channel and also be found to restrain the cdk activity at some extent. IC50: 14.23 uM (EC50, Ca2+ channel) 3.34 uM (EC50, cdk2). Uses: A ca2+ channel agonist that selectively acting on n-type ca2+ channel and also be found to restrain the cdk activity at some extent. Synonyms: Ca2+ channel agonist 1; SCHEMBL17628623; CS-5169; CS 5169; CS5169. Grade: 98%. CAS No. 1402821-24-2. Molecular formula: C19H26N6O. Mole weight: 354.46. | |
| Ca2+-transporting ATPase | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme family comprises three types of Ca2+-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in yeast. The first and third transport one ion per ATP hydrolysed, whereas the second transports two ions. Ca2+ is transported from the cytosol [side 1] into the sarcoplasmic reticulum in muscle cells [side 2]. Group: Enzymes. Synonyms: sarcoplasmic reticulum ATPase; sarco(endo)plasmic reticulum Ca2+-ATPase; calcium pump; Ca2+-pumping ATPase; plasma membrane Ca-ATPase. Enzyme Commission Number: EC 3.6.3.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4697; Ca2+-transporting ATPase; EC 3.6.3.8; sarcoplasmic reticulum ATPase; sarco(endo)plasmic reticulum Ca2+-ATPase; calcium pump; Ca2+-pumping ATPase; plasma membrane Ca-ATPase. Cat No: EXWM-4697. | |
| CA-4948 | CA-4948 is a potent and selective IRAK4 inhibitor that can be used for the treatment of cancers with dysregulated TLR/MYD88/IRAK4 signaling. Synonyms: CA-4948; CA 4948; CA4948; 6'-Amino-N-[2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl][2,3'-bipyridine]-6-carboxamide. Grade: >98%. CAS No. 1801343-74-7. Molecular formula: C21H19N7O3. Mole weight: 417.429. | |
| CA-5f | CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. It exhibited strong cytotoxicity against A549 non-small cell lung cancer (NSCLC) cells. CA-5f effectively suppressed the growth of A549 lung cancer xenograft as a single agent with an excellent tolerance in vivo. Synonyms: CA5f. Grade: ≥98%. CAS No. 1370032-19-1. Molecular formula: C24H24N2O3. Mole weight: 388.46. | |
| CA6, Positive Control (Carbonic Anhydrase 6, Carbonate Dehydratase VI, Carbonic Anhydrase VI, CA-VI, Salivary Carbonic Anhydrase, Secreted Carbonic Anhydrase) | Control for 139560. Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences. | Worldwide |
| CA77.1 | CA77.1 is a brain-penetrant and orally active activator of chaperone-mediated autophagy (CMA) for the treament of Alzheimer's disease (AD). Synonyms: CA. CAS No. 2412270-22-3. Molecular formula: C16H12ClN3O. Mole weight: 297.74. | |
| CA77.1 | CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics. CA77.1 is a derivative of AR7 (HY-101106) and can increase the expression of the lysosomal receptor LAMP2A in?lysosomes. CA77.1 improves behavior and neuropathology in PS19 mice model and can be used for alzheimer's?disease research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2412270-22-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134923. | |
| Cabamiquine | Cabamiquine (DDD107498) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC 50 of 1 nM against P. falciparum 3D7. Cabamiquine inhibits protein synthesis by targeting eEF2/CaMKIII , with an EC 50 of 2 nM for WT- Pf eEF2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDD107498; DDD-498; M5717. CAS No. 1469439-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117684. | |
| Cabamiquine succinate | Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC 50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII , with an EC 50 of 2 nM for WT- Pf eEF2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDD107498 succinate; DDD-498 succinate; M5717 succinate. CAS No. 2444781-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117684A. | |
| Cabastine | Cabastine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: levocabastine, Cabastinum, Cabastine, Cabastine [INN], UNII-COU3RRH769, HMS2090F18, CID189911, NCGC00016939-01, CAS-79547-78-7, 79449-98-2. Product Category: Heterocyclic Organic Compound. CAS No. 79449-98-2. Molecular formula: C26H29FN2O2. Mole weight: 420.525. Purity: 0.96. IUPACName: (3R,4S)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid. Canonical SMILES: CC1CN(CCC1(C2=CC=CC=C2)C(=O)O)C3CCC(CC3)(C#N)C4=CC=C(C=C4)F. Product ID: ACM79449982. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cabazitaxel | Cabazitaxel increases CYP3A enzyme activities in rat hepatocytes. The mean ex-vivo human plasma protein binding of Cabazitaxel is 91.6%. Synonyms: XRP6258; XRP-6258; XRP 6258; TXD 258; TXD-258; TXD258; RPR116258A; axoid XRP6258; dimethoxydocetaxel US brand name: Jevtana. Grade: >98%. CAS No. 183133-96-2. Molecular formula: C45H57NO14. Mole weight: 835.93. | |
| Cabazitaxel | Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Uses: Scientific research. Group: Natural products. Alternative Names: XRP6258; RPR-116258A; taxoid XRP6258. CAS No. 183133-96-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15459. | |
| Cabazitaxel | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C45H57NO14. CAS No. 183133-96-2. Prepack ID 58675245-100mg. Molecular Weight 835.93. See USA prepack pricing. |  |
| Cabazitaxel | A novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor. Group: Biochemicals. Alternative Names: (αR, βS)- β - [ [ (1, 1-Dimethylethoxy) carbonyl] amino] - α -hydroxy Benzene propanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4, 6-dimethoxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester; TXD 258; XRP 6258; β - [ [ (1, 1-Dimethylethoxy) carbonyl] amino] - α -hydroxy Benzene propanoic Acid [2aR-[2aα,4 β,4a β,6 β, 9α(αR*, βS*), 11α, 12α, 12aα, 12bα]]-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4, 6-dimethoxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. CAS No. 183133-96-2. Pack Sizes: 5mg, 50mg. US Biological Life Sciences. | Worldwide |
| Cabazitaxel-d6 | A labeled novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor. Group: Biochemicals. Alternative Names: (αR, βS)- β - [ [ (1, 1-Dimethylethoxy) carbonyl] amino] - α -hydroxy Benzene propanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4, 6-(dimethoxy-d6)-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester; TXD 258-d6; XRP 6258-d6; β - [ [ (1, 1-Dimethylethoxy) carbonyl] amino] - α -hydroxy Benzene propanoic Acid [2aR-[2aα,4 β,4a β,6 β, 9α(αR*, βS*), 11α, 12α, 12aα, 12bα]]-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4, 6-(dimethoxy-d6)-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cabazitaxel-[d9] | Cabazitaxel-[d9] is the labelled analogue of Cabazitaxel, which is a microtubule inhibitor used as a chemotherapy to treat prostate cancer. Synonyms: Cabazitaxel D9; (alphaR,betaS)-beta-[[[1,1-di(methyl-d3)ethoxy-2,2,2-d3]carbonyl]amino]-alpha-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester; Jevtana-d9; kabazitaxel-d9. Grade: >95%. CAS No. 1383572-19-7. Molecular formula: C45H48D9NO14. Mole weight: 844.99. | |
| Cabazitaxel Impurity | 10-Deacetyl-7,10-dimethoxy-Baccatin III is an intermediate used to prepare Cabazitaxel. Synonyms: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one; [2aR-(2aα,4β,4aβ,6β,9α,11α,12α,12aα. Grade: > 95%. CAS No. 183133-94-0. Molecular formula: C31H40O10. Mole weight: 572.66. | |
| Cabazitaxel Impurity 12 | an impurity of cabazitaxel. Synonyms: 2-Azetidinone, 3-hydroxy-4-phenyl-, (3S,?4R)?-. Grade: > 95%. CAS No. 146924-92-7. Molecular formula: C9H9NO2. Mole weight: 163.18. | |
| Cabazitaxel Impurity 15 | an impurity of an antineoplastic agent cabazitaxel. Synonyms: 3,?5-Oxazolidinedicarboxy?lic acid, 2-(4-methoxyphenyl)?-4-phenyl-, 3-(1,?1-dimethylethyl) ester, (4R,?5S)?-. Grade: > 95%. CAS No. 859498-34-3. Molecular formula: C22H25NO6. Mole weight: 399.45. | |
| Cabazitaxel Impurity 9 | Cabazitaxel Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153415-46-4. Molecular formula: C44H53NO14. Mole weight: 819.9. Catalog: APB153415464. | |
| Cabazitaxel Impurity (DiTroc) | A intermediate in the synthesis of a metabolite of Docetaxel, an antineoplastic. Synonyms: Carbonic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,6-diyl bis(2,2,2-trichloroethyl) E. Grade: > 95%. CAS No. 95603-44-4. Molecular formula: C35H38Cl6O14. Mole weight: 895.4. | |
| Cabazitaxel Impurity (Oxazolidine Protected) | Oxazolidine Cabazitaxel is an impurity of Cabazitaxel which is a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cycl. Grade: > 95%. CAS No. 1373171-12-0. Molecular formula: C48H61NO14. Mole weight: 876.02. | |
| Cabazitaxel intermediate | Cabazitaxel intermediate is extracted from the barks of Taxus yunnanensis. Synonyms: 5-[(2α,5β,7β,10β,13α)-4-Acetoxy-2-(benzoyloxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-13-yl] 3-(2-methyl-2-propanyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate; 3,5-Oxazolidinedicarboxylic acid, 2-(4-methoxyphenyl)-4-phenyl-, 5-[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl] 3-(1,1-dimethylethyl) ester, (4S,5R)-; Cabazitaxel N-2; Docetaxel Impurity 62. Grade: 97.0%. CAS No. 1354900-65-4. Molecular formula: C51H59NO15. Mole weight: 926.02. | |
| Cabazitaxel N-1 | Cabazitaxel N-1 is an impurity of Cabazitaxel, a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. Synonyms: 5-((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-12-(benzoyloxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl) 3-(tert-butyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyloxazolidine-3,5-dicarboxylate. CAS No. 1354900-66-5. Molecular formula: C53H63NO15. Mole weight: 954.07. | |
| Cabazitaxel N-3 | Cabazitaxel N-3 is an impurity of Cabazitaxel, a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. CAS No. 859498-31-0. Molecular formula: C57H61Cl6NO19. Mole weight: 1276.81. | |
| Cabergoline | Cabergoline is a lysergic acid amide derivative and a potent dopamine D2 receptor agonist. It has been used for monotherapy of Parkinson's disease in the early phase. It has a direct inhibitory effect on pituitary lactotroph (prolactin) cells. It acts on dopamine receptors in lactophilic hypothalamus cells to suppress prolactin production in the pituitary gland. It has been used as a first-line agent in the management of prolactinomas due to its higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine. It is developed by Johnson & Johnson. It has been approved the listing. Uses: Cabergoline has been used for monotherapy of parkinson's disease in the early phase. it has been used as a first-line agent in the management of prolactinomas. Synonyms: CG-101; FCE-21336; CG 101; FCE 21336; CG101; FCE21336; Cabaser; Cabaseril; 6-Allyl-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)ergoline-8-carboxamide; (8-Beta)-(2-propenyl); n-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-ergoline-8-carboxamide; Cabergolinum; (8β)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-ergoline-8-carboxamide. Grade: >98%. CAS No. 81409-90-7. Molecular formula: C26H37N5O2. Mole weight: 451.60. | |
| Cabergoline | Cabergoline is an ergot derived-dopamine D 2 -like receptor agonist that has high affinity for D 2 , D 3 , and 5-HT 2B receptors ( K i =0.7, 1.5, and 1.2, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE-21336. CAS No. 81409-90-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15296. | |
| Cabergoline | Cabergoline. Group: Biochemicals. Grades: Purified. CAS No. 81409-90-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Cabergoline-d3 | A labeled dopamine D2-receptor agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Cabergoline EP Impurity B | Cabergoline EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6aR,9R,10aR)-7-allyl-N9-(3-(dimethylamino)propyl)-N4-ethyl-6a,7,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9(6H)-dicarboxamide. CAS No. 166533-36-4. Molecular formula: C26H37N5O2. Mole weight: 451.6. Catalog: APB166533364. | |
| Cabergoline. (FCE-21336, Cabaser, Dostinex) | A dopamine D2-receptor agonist. Group: Biochemicals. Alternative Names: FCE-21336, Cabaser, Dostinex. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Cabergoline Impurity 12 | Cabergoline Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153415-36-2. Molecular formula: C23H33N5O2. Mole weight: 411.55. Catalog: APB153415362. | |
| Cabergoline Impurity 13 | Cabergoline Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1075250-72-4. Molecular formula: C22H32N2OSi. Mole weight: 368.6. Catalog: APB1075250724. | |
| Cabergoline Impurity 15 | Cabergoline Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1075250-74-6. Molecular formula: C21H32N2OSi. Mole weight: 356.58. Catalog: APB1075250746. | |
| Cabergoline Impurity 18 | Cabergoline Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1075250-76-8. Molecular formula: C25H32N2O6. Mole weight: 456.54. Catalog: APB1075250768. | |
| Cabergoline Impurity 19 | Cabergoline Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1075250-77-9. Molecular formula: C16H19ClN2O2. Mole weight: 306.79. Catalog: APB1075250779. | |
| Cabergoline Impurity 20 | Cabergoline Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1075250-75-7. Molecular formula: C25H34N2O5. Mole weight: 442.56. Catalog: APB1075250757. | |
| Cabergoline Impurity A | 6-Allyl-8β-carboxyergoline is a metabolite of cabergoline which is a dopamine D2-receptor agonist. Synonyms: (8β)-6-(2-Propen-1-yl)-ergoline-8-carboxylic Acid; 6-(2-Propenyl)dihydrolysergic Acid; FCE 21589. Grade: > 95%. CAS No. 81409-74-7. Molecular formula: C18H20N2O2. Mole weight: 296.37. | |
| Cabergoline impurity B | Cabergoline impurity B. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (6aR,9R,10aR)-9-N-[3-(dimethylamino)propyl]-4-N-ethyl-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9-dicarboxamide. Appearance: White to Off-White Solid. CAS No. 166533-36-4. Molecular formula: C26H37N5O2. Mole weight: 451.6. Purity: 0.97. Product ID: ACM166533364. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cabergoline Impurity B | European Pharmacopoeia (EP) Impurity B of Cabergoline. Synonyms: (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propen-1-yl)-ergoline-1,8-dicarboxamide; (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-6-(2-propenyl)-ergoline-1,8-dicarboxamide; Cabergoline EP Impurity B. Grade: > 95%. CAS No. 166533-36-4. Molecular formula: C26H37N5O2. Mole weight: 451.62. | |
| Cabergoline Impurity C | European Pharmacopoeia (EP) Impurity C of Cabergoline. Synonyms: (8β)-N8-[3-(Dimethylamino)propyl]-N1-ethyl-N8-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-ergoline-1,8-dicarboxamide; (8β)-N8-[3-(dimethylamino)propyl]-N1-ethyl-N8-[(ethylamino)carbonyl]-6-(2-propenyl)--ergoline-1,8-dicarboxamide. Grade: > 95%. CAS No. 126554-50-5. Molecular formula: C29H42N6O3. Mole weight: 522.7. | |
| Cabergoline Impurity D | A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum. Synonyms: N-[3-(Dimethylamino)propyl]-6-(2-propen-1-yl)-(8β)-ergoline-8-carboxamide; (5R,8R,10R)-6-Allyl-N-[3-(dimethylamino)propyl]ergoline-8-carboxamide; FCE 21590. Grade: > 95%. CAS No. 85329-86-8. Molecular formula: C23H32N4O. Mole weight: 380.54. | |
| Cabergoline N-Oxide | The N-oxide of Cabergoline , a dopamine D2-receptor agonist. Group: Biochemicals. Alternative Names: (3-{{ [6aR, 9R, 10aR) -7-Allyl-4, 6, 6a, 7, 8, 9, 10, 10a-octahydroindolo [4, 3-fg]quinolin-9yl]carbonyl} [ethylamino) carbonyl]amino}propyl) (dimethyl) ammoniumolate. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Cabiralizumab | Cabiralizumab (FPA 008) is an anti- CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FPA 008; Anti-Human CSF1R Recombinant Antibody. CAS No. 1613144-80-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99259. | |
| Cab-O-Sil M5 NF/EP | Cab-O-Sil® M-5. Grades: Scintillation Grade . CAS No. 7631-86-9. Product ID: 8-01595. Molecular formula: SiO2. Mole weight: 60.08 . |  |
| Cabotegravir | Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744; S/GSK1265744. CAS No. 1051375-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592. | |
| Cabotegravir | Cabotegravir. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S,11aR)-N-(2,4-difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide. CAS No. 1051375-10-0. Molecular formula: C19H17F2N3O5. Mole weight: 405.11. Catalog: APB1051375100. | |
| Cabotegravir (GSK744, GSK1265744) | Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2. Uses: Hiv integrase inhibitors. Synonyms: S/GSK1265744; S/GSK 1265744; S/GSK-1265744; GSK744; GSK-744; GSK 744; Cabotegravir. Grade: >98%. CAS No. 1051375-10-0. Molecular formula: C19H17F2N3O5. Mole weight: 405.35. | |
| Cabotegravir Impurity 9 | Cabotegravir Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-methoxy-6-(methoxycarbonyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-3-carboxylic acid. CAS No. 1335210-31-5. Molecular formula: C11H11NO7. Mole weight: 269.05. Catalog: APB1335210315. | |
| Cabotegravir sodium | Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir sodium can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744 sodium; S/GSK1265744 sodium. CAS No. 1051375-13-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592A. | |
| Caboxine A | Caboxine A is isolated from the herbs of Catharanthus roseus. Synonyms: 3-epi-Isocaboxine A; 3-epi-Vineridine; 7-epi-Caboxine B; Methyl (7α,19α,20α)-11-methoxy-19-methyl-2-oxoformosanan-16-carboxylate. Grade: 96%. CAS No. 53851-13-1. Molecular formula: C22H26N2O5. Mole weight: 398.5. | |
| Cabozantinib | Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Grade: >98%. CAS No. 849217-68-1. Molecular formula: C28H24FN3O5. Mole weight: 501.51. | |
| Cabozantinib | Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET , with IC 50 values of 0.035, and 1.3 nM, respectively. Cabozantinib displays strong inhibition of KIT , RET , AXL , TIE2 , and FLT3 ( IC 50 =4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib shows antiangiogenic activity. Cabozantinib disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL184; BMS-907351. CAS No. 849217-68-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13016. | |
| Cabozantinib-d4 L-Malate Salt | Cabozantinib-d4 L-Malate Salt. Group: Biochemicals. Alternative Names: N- [4- [ (6, 7-Dimethoxy-4-quinolinyl) oxy] phenyl] -N'- (4-fluorophenyl) -1, 1-cyclopropane dicarboxamide-d4 (2S)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cabozantinib Des-O-fluoroaniline | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic acid; Cabozantinib Impurity 03. CAS No. 849217-77-2. Molecular formula: C22H20N2O6. Mole weight: 408.40. | |
| Cabozantinib, Free Base, 99+% | Cabozantinib, also known as XL184, is an orally bioavailable novel tysosine kinase inhibitor of c-MET and VEGF receptor 2 (VEGFR2). It inhibited MET and VEGFR2 with IC50 values of 1.3 nM and 35 pM, respectively. It also inhibited MET-activating kinase domain mutations Y1248H, D1246N, or K1262R with IC50 values of 3.8, 11.8, and 14.6 nM, respectively. It strongly inhibited several kinases that are implicated in tumor pathobiology including KIT, RET, AXL, TIE2, and FLT3 with IC50 values of 4.6, 5.2, 7, 14.3, and 11.3 nM, respectively. In cellular assays, cabozantinib inhibited phosphorylation of MET, VEGFR2, KIT, FLT3, and AXL with IC50 values of 7.8, 1.9, 5.0, 7.5, and 42 [micro]M, respectively. Cabozantinib inhibited tumor angiogenesis, tumor growth and metastasis in cancers with dysregulated MET and VEGFR signaling. Yakes F.M., et al "Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth." Mol. Cancer Ther. 10: 229 Group: Biochemicals. Alternative Names: BMS-907351; XL-184; Cometriq; N- [4- [ (6, 7-Dimethoxy-4-quinolinyl) oxy] phenyl] -N- (4-fluorophenyl) -1, 1-cyclopropane dicarboxamide (2S)-2-Hydroxybutanedioic Acid. Grades: Highly Purified. CAS No. 849217-68-1. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Cabozantinib impurity 59 | Cabozantinib impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-ethoxy-3-oxopropanoic acid. CAS No. 1071-46-1. Molecular formula: C5H8O4. Mole weight: 132.11. Catalog: APB1071461. | |
| Cabozantinib L-Malate Salt | Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis. Group: Biochemicals. Alternative Names: N- [4- [ (6, 7-Dimethoxy-4-quinolinyl) oxy] phenyl] -N- (4-fluorophenyl) -1, 1-cyclopropane dicarboxamide (2S)-2-Hydroxybutanedioic Acid; Cabozantinib S-Malate; BMS-907351; XL-184; Cometriq. Grades: Highly Purified. CAS No. 849217-68-1. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Cabozantinib Malate | It mainly targets MET and VEGFR2 tyrosine kinases, which are related to the growth and spread of prostate cancer, and inhibits tumor metastasis and angiogenesis. CAS No. 1140909-48-3. Product ID: PAP-0093. Molecular formula: C32H30FN3O10. Product Keywords: Other Active Pharmaceutical Ingredients; Cabozantinib Malate; PAP-0093; ; C32H30FN3O10; 1140909-48-3. Appearance: Solid. Color: White to Off-White. EC Number: 691-711-0. Physical State: Solid. Solubility: DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly). Storage: Sealed in dry,Room Temperature. Applications: For the treatment of progressive and metastatic medullary thyroid cancer. Melting Point: 166-169°C. |  |
| Cabozantinib N-oxide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 4-(4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6,7-dimethoxyquinoline 1-oxide; 1,1-Cyclopropanedicarboxamide, N-(4-((6,7-dimethoxy-1-oxido-4-quinolinyl)oxy)phenyl)-N'-(4-fluorophenyl)-; Cabozantinib Impurity 04. CAS No. 1621681-63-7. Molecular formula: C28H24FN3O6. Mole weight: 517.51. | |
| Cabozantinib S-malate | Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: Cabozantinib malate; cabozantinib (S)-malate; Cabometyx; 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2S)-2-hydroxybutanedioic acid. Grade: >98%. CAS No. 1140909-48-3. Molecular formula: C28H24FN3O5.C4H6O5. Mole weight: 635.59. | |
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