A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An antimicrobial agent. Group: Biochemicals. Alternative Names: (6R, 7R) -3-[ (Acetyloxy) methyl]-8-oxo-7-[[ (4-pyridinylthio) acetyl]amino]-5-thia-1-azabicyclo[4. 2. 0]oct-2-ene-2-carboxylic Acid; (6R-trans) -3-[ (Acetyloxy) methyl]-8-oxo-7-[[ (4-pyridinylthio) acetyl]amino]-. Grades: Highly Purified. CAS No. 21593-23-7. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Cephapirin benzathine
Cephapirin benzathine is a first-generation cephalosporin with a broad spectrum of activity against gram-positive and gram-negative organisms. Its resistance to β-lactamase is higher than that of the penicillin family. commonly used in the veterinary field. Synonyms: Cefapirin benzathine. CAS No. 97468-37-6. Molecular formula: C50H54N8O12S4. Mole weight: 1087.27.
Cephapirin benzathine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Cephapirin benzathine
Cephapirin benzathine. Group: Biochemicals. Grades: Highly Purified. CAS No. 97468-37-6. Pack Sizes: 100g, 250g, 500g, 1Kg, 2Kg. US Biological Life Sciences.
Worldwide
Cephapirin Benzathine
Cephapirin Benzathine is the benzathine salt form of cephapirin. Cephapirin Benzathine is the first generation cephalosporin with broad spectrum antibiotic activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 97468-37-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-113735.
Cephapirin Control Peptide
Cephapirin Control Peptide. Group: Molecular Biology. Pack Sizes: 1x1ml. US Biological Life Sciences.
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Cephapirin-d4
Labeled Cephapirin. An antimicrobial agent. Group: Biochemicals. Alternative Names: (6R,7R)-3-[(Acetyloxy)methyl]-8-oxo-7-[[(4-pyridinylthio-d4)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R-trans)-3-[(Acetyloxy)methyl]-8-oxo-7-[[(4-pyridinylthio-d4)acetyl]amino]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cephapirin sodium
Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cefapirin sodium. CAS No. 24356-60-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg. Product ID: HY-A0153A.
Cephapirin Sodium
Cephapirin is a cephalosporin antibiotic agent. Uses: Anti-bacterial agents. Synonyms: sodium;(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cephapirin Sodium; Cefapirin sodium; Cephap; BL P 1322; BL-P 1322; BLP 1322. NSC 179171. Grades: Assay: 855 - 1000 ug/mg. CAS No. 24356-60-3. Molecular formula: C17H16N3NaO6S2. Mole weight: 445.44.
Cepharanthine is a natural product isolated from the plant Stephania?cephalantha?Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activity. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46?μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: o-Methylcepharanoline. Product Category: Inhibitors. Appearance: Solid. CAS No. 481-49-2. Molecular formula: C37H38N2O6. Mole weight: 606.71. Purity: 0.98. IUPACName: (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaene. Canonical SMILES: CN1CCC2=CC3=C(C4=C2[C@@H]1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)C[C@@H]7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3. Product ID: ACM481492. Alfa Chemistry ISO 9001:2015 Certified.
Cepharanthine
Cepharanthine. Group: Biochemicals. Alternative Names: 12-O-Methylcepharanoline. Grades: Plant Grade. CAS No. 481-49-2. Pack Sizes: 20mg. Molecular Formula: C37H38N2O6, Molecular Weight: 606.706999999999. US Biological Life Sciences.
Cepharanthine is a natural product that can be isolated from the plant Stephania?cephalantha?Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration ( IC 50 ) and 90% inhibitory concentration ( IC 90 ) values of 1.90 and 4.46?μM [1]. Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model [2] [3]. Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. CAS No. 481-49-2. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-N6972.
Cephemimycin
It is produced by the strain of Streptomyces jumonjinensis (NRRL 5741). It has weak antibacterial and antifungal activity. The removed side chain can be used as raw material for semisynthetic cephalosporin. Synonyms: Cephamycin C; antibiotic 842A; (6R,7S)-3-[[(aminocarbonyl)oxy]methyl]-7alpha-[[(R)-5-amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; A16886B; A 16886B; A-16886B. CAS No. 34279-51-1. Molecular formula: C16H22N4O9S. Mole weight: 446.43.
Cephradine
Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cefradine; SQ-11436. CAS No. 38821-53-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1156.
Cephradine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Cephradine hydrate
1g Pack Size. Group: Antibiotics. Formula: C16H19N3O4S. CAS No. 38821-53-3. Prepack ID 12855736-1g. Molecular Weight 349.4. See USA prepack pricing.
Cephradine monohydrate
Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cefradine monohydrate. CAS No. 75975-70-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-128449.
Cephradine monohydrate
Cephradine monohydrate is the first generation cephalosporin, which is active against a wide range of Gram-positive and Gram-negative bacteria. Synonyms: Cefradine hydrate; [6R-[6alpha,7beta(R*)]]-7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate; Anspor monohydrate; Sefril monohydrate; Velosef monohydrate. Grades: ≥96%. CAS No. 75975-70-1. Molecular formula: C16H19N3O4S.H2O. Mole weight: 367.42.
c-(ε-ApGp)
c-(ε-ApGp) is a fluorescent analogue of c-(ApGp). Grades: ≥ 95% by HPLC. Molecular formula: C22H24N10O13P2 (free acid). Mole weight: 698.4 (free acid).
Ceralasertib (AZD6738) is an orally active and bioavailable inhibitor of ATR kinase with an IC 50 of 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6738. CAS No. 1352226-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19323.
Ceralifimod (ONO-4641) is a selective agonist of sphingosine 1-phosphate (S1P) receptor 1 and 5 (EC50 = 0.0273 and 0.334?nM). In animal experiment, ONO-4641 prevented relapse of disease in a non-obese diabetic mouse model of relapsing-remitting EAE. ONO-4641 had been developed for the treatment of multiple sclerosis (MS) and undergone a phase II clinical trial by Merck KGaA and Ono, therefore, the study were terminated in Dec 2014. Uses: Ceralifimod (ono-4641) is a selective agonist of sphingosine 1-phosphate (s1p) receptor 1 and 5 (ec50 = 0.0273 and 0.334?nm) developed for the treatment of multiple sclerosis (ms). Synonyms: ONO-4641; ONO 4641; ONO4641; Ceralifimod. UNII-BZ2O8A84A4; 891859-12-4; AK173892; Ceralifimod [INN]; SCHEMBL465051; 1-[[6-[(2-methoxy-4-propylphenyl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid. Grades: ≥98%. CAS No. 891859-12-4. Molecular formula: C27H33NO4. Mole weight: 435.564.
Ceramic Deflocculant
Ceramic Deflocculant. Group: Glass additives.
Ceramic Etchant A
Ceramic Etchant A. Group: Electronic materials.
Ceramic Substrate
Ceramic Substrate. Group: Single crystal substrates. > 99.95 %.
ceramidase
Ceramidase (EC 3.5.1.23, acylsphingosine deacylase, glycosphingolipid ceramide deacylase) is an enzyme which cleaves fatty acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P). Group: Enzymes. Synonyms: acylsphingosine deacylase; glycosphingolipid ceramide deacylase. Enzyme Commission Number: EC 3.5.1.23. CAS No. 37289-06-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4413; ceramidase; EC 3.5.1.23; 37289-06-8; acylsphingosine deacylase; glycosphingolipid ceramide deacylase. Cat No: EXWM-4413.
Ceramide
Cas No. 3102-57-6.
Ceramide
Ceramide. Group: Biochemicals. Grades: Purified. CAS No. 3102-57-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ceramide 1-phosphate
Ceramide 1-phosphate is a bioactive lipid and one of the key components of sphingolipids. Ceramide 1-phosphate playing diverse roles in cellular behaviors such as cell differentiation, migration, proliferation and death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 128543-23-7. Pack Sizes: 1 mg. Product ID: HY-P2982.
Ceramide 1-phosphate
Ceramide 1-phosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [(E,2S,3R)-3-hydroxy-2-(octadecanoylamino)octadec-4-enyl] dihydrogen phosphate. Product Category: Heterocyclic Organic Compound. CAS No. 128543-23-7. Molecular formula: C36H72NO6P. Mole weight: 645.933742 [g/mol]. Purity: 0.96. IUPACName: [(E,2S,3R)-3-hydroxy-2-(octadecanoylamino)octadec-4-enyl] dihydrogen phosphate. Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)NC(COP(=O)(O)O)C(C=CCCCCCCCCCCCCC)O. Product ID: ACM128543237. Alfa Chemistry ISO 9001:2015 Certified. Categories: CerP(d18:1/18:0).
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer(t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer(t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer(t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Stearoyl phytosphingosine. CAS No. 34354-88-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141582.
ceramide cholinephosphotransferase
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-choline:N-acylsphingosine cholinephosphotransferase. This enzyme is also called phosphorylcholine-ceramide transferase. This enzyme participates in sphingolipid metabolism. Group: Enzymes. Synonyms: phosphorylcholine-ceramide transferase. Enzyme Commission Number: EC 2.7.8.3. CAS No. 9026-14-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3329; ceramide cholinephosphotransferase; EC 2.7.8.3; 9026-14-6; phosphorylcholine-ceramide transferase. Cat No: EXWM-3329.
Sphingosine and dihydrosphingosine can also act as acceptors; CDP-glucose can act as donor. Group: Enzymes. Synonyms: UDP-glucose:ceramide glucosyltransferase; ceramide:UDP-Glc glucosyltransferase; uridine diphosphoglucose-ceramide glucosyltransferase; ceramide:UDP-glucose glucosyltransferase; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.80. CAS No. 37237-44-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2621; ceramide glucosyltransferase; EC 2.4.1.80; 37237-44-8; UDP-glucose:ceramide glucosyltransferase; ceramide:UDP-Glc glucosyltransferase; uridine diphosphoglucose-ceramide glucosyltransferase; ceramide:UDP-glucose glucosyltransferase; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase. Cat No: EXWM-2621.
ceramide kinase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:ceramide 1-phosphotransferase. This enzyme is also called acylsphingosine kinase. This enzyme participates in sphingolipid metabolism. Group: Enzymes. Synonyms: acylsphingosine kinase. Enzyme Commission Number: EC 2.7.1.138. CAS No. 123175-68-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2969; ceramide kinase; EC 2.7.1.138; 123175-68-8; acylsphingosine kinase. Cat No: EXWM-2969.
Ceramide Powder is the latest moisturizer developed recently. It is a type of phospholipid with ceramide as a skeleton. Ceramide phosphocholine and ceramide phosphoethanolamine are the main components. Phospholipid is the main component of the cell membrane, and the stratum corneum 40%~50% sebum is composed of Ceramide Powder. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide. Appearance: Crystalline solid. CAS No. 100403-19-8. Molecular formula: C24H47NO3. Mole weight: 397.63. Purity: 0.98. Density: 0.928 g/cm³. ECNumber: 309-560-3. Product ID: ACM100403198. Alfa Chemistry ISO 9001:2015 Certified.
Ceranib 1
Ceranib 1. Group: Biochemicals. Grades: Purified. CAS No. 328076-61-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ceranib 1
Ceranib 1 is a ceramidase inhibitor. It inhibits proliferation in SKOV3 ovarian carcinoma cells. It decreases sphingosine and sphingosine-1-phosphate (S1P) levels in SKOV3 cells and induces accumulation of ceramide species. It is a useful research chemical and has an antiproliferative effect. Synonyms: 3-[(2E)-3-(4-Methoxyphenyl)-1-oxo-2-propen-1-yl]-6-methyl-4-phenyl-2(1H)-quinolinone; 6-Methyl-3-[3-(4-methoxyphenyl)-1-oxo-2-propenyl]-4-phenyl-2(1H)-quinolinone. Grades: ≥98% by HPLC. CAS No. 328076-61-5. Molecular formula: C26H21NO3. Mole weight: 395.45.
Ceranib-2
Ceranib-2 is an inhibitor of cellular ceramidase activity, which can inhibit ceramidase activity with IC50 of 28 μM in SKOV3 cells. It can catalyze the hydrolysis of the N-acyl linkage between the fatty acid and sphingosine base in ceramide to produce sphingosine and a free fatty acid. Ceranib-2 decreases levels of sphingosine and sphingosine-1-phosphate (S1P), and inhibits cell proliferation. Grades: ≥98%. CAS No. 1402830-75-4. Molecular formula: C25H19NO3. Mole weight: 381.4.
A cell-permeable, potent inhibitor of ceramidase (IC50=28mM) with anti-proliferative and proapoptotic properties. Shown to block the proliferation of SKVO3, ovarian adenocarcinma cells (IC50=730nM) in the G2/M phase. When used in combination with paclitaxel, it increases tumor chemosentitvity and exhibits additive chemotherapeutic effects. Reduces tumor burden in Balb/c mice when administered intraperitoneally (20-50mg/kg) without affecting the total body weight. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??NO?, Molecular Weight: 381.4. US Biological Life Sciences.
Worldwide
Ceraphyl 31
Mixture of Lauryl Lactate, Myristyl Lactate, and Cetyl Lactate. CAS No. 6283-92-7. Product ID: 8-04901.
Ceratamine a
Ceratamine A is an antimitotic heterocyclic alkaloid isolated from the marine sponge Pseudoceratina sp., acts as a microtubule-stabilizing agent. Ceratamine A exhibits cytotoxicity against human cancer cell lines. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[(3,5-Dibromo-4-methoxyphenyl)methyl]-6-methyl-2-(methylamino)imidazo[4,5-d]azepin-5(6H)-one. Product Category: Inhibitors. CAS No. 634151-15-8. Molecular formula: C17H16Br2N4O2. Mole weight: 468.14. Purity: 0.96. IUPACName: 4-[(3,5-dibromo-4-methoxyphenyl)methyl]-6-methyl-2-(methylamino)imidazo[4,5-d]azepin-5-one. Canonical SMILES: O=C(N(C)C=C1)C(CC2=CC(Br)=C(OC)C(Br)=C2)=C3C1=NC(NC)=N3. Density: 1.722g/cm³. Product ID: ACM634151158. Alfa Chemistry ISO 9001:2015 Certified.
Ceratamine A
An antimitotic heterocyclic alkaloid isolated from the marine sponge Pseudoceratina sp. collected in Papua New Guinea. Uses: An antimitotic heterocyclic alkaloid isolated from the marine sponge pseudoceratina sp. collected in papua new guinea. Synonyms: 4-[(3,5-Dibromo-4-methoxyphenyl)methyl]-6-methyl-2-(methylamino)imidazo[4,5-d]azepin-5(6H)-one. CAS No. 634151-15-8. Molecular formula: C17H16Br2N4O2. Mole weight: 468.14.
Ceratamine A
Ceratamine A. Group: Biochemicals. Alternative Names: 4-[ (3, 5-Dibromo-4-methoxyphenyl) methyl]-6-methyl-2- (methylamino) imidazo[4, 5-d]azepin-5 (6H) -one. Grades: Highly Purified. CAS No. 634151-15-8. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C17H16Br2N4O2. US Biological Life Sciences.
Worldwide
Ceratamine B
Ceratamine B. Group: Biochemicals. Alternative Names: 4-[ (3, 5-Dibromo-4-methoxyphenyl) methyl]-2- (methylamino) imidazo[4, 5-d]azepin-5 (6H) -one. Grades: Highly Purified. CAS No. 634151-16-9. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C16H14Br2N4O2. US Biological Life Sciences.
Worldwide
Ceratamine B
An antimitotic heterocyclic alkaloid isolated from the marine sponge Pseudoceratina sp. collected in Papua New Guinea. Uses: An antimitotic heterocyclic alkaloid isolated from the marine sponge pseudoceratina sp. collected in papua new guinea. Synonyms: 4-[(3,5-Dibromo-4-methoxyphenyl)methyl]-2-(methylamino)imidazo[4,5-d]azepin-5(6H)-one. CAS No. 634151-16-9. Molecular formula: C16H14Br2N4O2. Mole weight: 454.12.
Ceratonia occurs as a yellow-green or white colored powder. Although odorless and tasteless in the dry powder form, ceratonia acquires a leguminous taste when boiled in water. Synonyms: Algaroba; carob bean gum; carob flour; ceratonia gum; ceratonia siliqua; ceratonia siliqua gum; Cheshire gum; E410; gomme de caroube; locust bean gum; Meyprofleur; St Johns bread. CAS No. 9000-40-2. Product ID: PE-0468. Category: Controlled-release Agents; Stabilizing Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents. Product Keywords: Binder Excipients; Stabilizers; Suspending Agents; ; PE-0468; Ceratonia; Controlled-release Agents; Stabilizing Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents; ; 9000-40-2. UNII: V4716MY704. Chemical Name: Carob gum. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: oral tablet. Stability and Storage Conditions: The bulk material should be stored in a well-closed container in a cool, dry place. Ceratonia loses not more than 15% of its weight on drying. Source and Preparation: Ceratonia is a naturally occurring material obtained from the ground endosperms separated from the seeds of the locust bean tree, Ceratonia siliqua (Leguminosae). The tree is indigenous to southern Europe and the Mediterranean region. Applications: Ceratonia is a naturally occurring material generally used as a substitute for tragacanth or other similar gums. A ceratoni
Ceratotoxin A
Ceratotoxin A is a peptide with 29 residues isolated from the accessory gland secretion fluid. It has strong antibacterial activity. Synonyms: Ser-Ile-Gly-Ser-Ala-Leu-Lys-Lys-Ala-Leu-Pro-Val-Ala-Lys-Lys-Ile-Gly-Lys-Ile-Ala-Leu-Pro-Ile-Ala-Lys-Ala-Ala-Leu-Pro; L-Proline, L-seryl-L-isoleucylglycyl-L-seryl-L-alanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-prolyl-L-valyl-L-alanyl-L-lysyl-L-lysyl-L-isoleucylglycyl-L-lysyl-L-isoleucyl-L-alanyl-L-leucyl-L-prolyl-L-isoleucyl-L-alanyl-L-lysyl-L-alanyl-L-alanyl-L-leucyl-. Grades: ≥95% by HPLC. CAS No. 150671-04-8. Molecular formula: C135H243N35O32. Mole weight: 2868.59.
Ceratotoxin B
Ceratotoxin B is an antimicrobial peptide produced by the sexually mature female of Ceratitis capitata. Synonyms: Ser-Ile-Gly-Ser-Ala-Phe-Lys-Lys-Ala-Leu-Pro-Val-Ala-Lys-Lys-Ile-Gly-Lys-Ala-Ala-Leu-Pro-Ile-Ala-Lys-Ala-Ala-Leu-Pro; L-Proline, L-seryl-L-isoleucylglycyl-L-seryl-L-alanyl-L-phenylalanyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-prolyl-L-valyl-L-alanyl-L-lysyl-L-lysyl-L-isoleucylglycyl-L-lysyl-L-alanyl-L-alanyl-L-leucyl-L-prolyl-L-isoleucyl-L-alanyl-L-lysyl-L-alanyl-L-alanyl-L-leucyl-; Ceratotoxin B protein, Ceratitis capitata. Grades: ≥95% by HPLC. CAS No. 150671-05-9. Molecular formula: C135H235N35O32. Mole weight: 2860.53.
Ceratotoxin-C
Ceratotoxin-C is from Ceratitis capitata. Ceratotoxin-C is a female-specific peptide with potent activity against Gram-positive and Gram-negative bacteria. It has hemolytic activity as well.
Ceratotoxin-D
Ceratotoxin-D is from Ceratitis capitata. Ceratotoxin-D is a female-specific peptide with potent activity against Gram-positive and Gram-negative bacteria. It has hemolytic activity as well.
Cercosporamide
Cercosporamide is a potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3. Cercosporamide effectively inhibits eIF4E phosphorylation as well as inibitiing inhibits Pkc1. Cercosporamide displays antiproliferative and proapoptotic activity in cancer cells in vitro. Group: Biochemicals. Alternative Names: (9aS) -8-Acetyl -9, 9a-di hydro-1, 3, 7-tri hydroxy-9a- methyl -9-oxo-4-dibenzofurancarboxamid e ; (S)-8-Acetyl -9, 9a-di hydro-1, 3, 7-tri hydroxy-9a- methyl -9-oxo-4-dibenzofurancarboxamid e ; (-)-Cercosporamide. Grades: Highly Purified. CAS No. 131436-22-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cercosporamide
Cercosporamide, a natural antifungal phytotoxin produced by Cercosporidium sp. MST-FP1899, has been found to be a selective Mnk inhibitor and shows probable antileukemic effects. Uses: Insecticide. Synonyms: (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide; (S)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancarboxamide; (-)-Cercosporamide. Grades: >95%. CAS No. 131436-22-1. Molecular formula: C16H13NO7. Mole weight: 331.28.
Cercosporin is produced by a plant pathogen, Pseudocercosporella capsellae. Cercosporin is a potent photosensitizer with a short activation wavelength, mostly suitable for superficial photodynamic therapy ( PDT ) treatments, especially when it is necessary to avoid perforations [1]. Cercosporin contains the perylenequinone structural features necessary to PKC activity with an IC 50 of 0.6-1.3 μM [2]. Uses: Scientific research. Group: Natural products. Alternative Names: CGP049090. CAS No. 35082-49-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6743.
Cercosporin
Phytotoxin. Potent and specific PKC inhibitor. Competes for the phorbol binding site. Anticancer compound. Cytotoxic. Antiproliferative. Antiparasitic. Antimicrobial. Group: Biochemicals. Alternative Names: NSC 153111. Grades: Highly Purified. CAS No. 35082-49-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C29H26O10. US Biological Life Sciences.
Worldwide
Cercosporin
CGP049090 is a novel inhibitor of Wnt/beta-catenin/lef-1 signaling inducing apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo. Synonyms: CGP049090; NSC 153111. Grades: >98% by HPLC. CAS No. 35082-49-6. Molecular formula: C29H26O10. Mole weight: 534.51.
Cerdulatinib
Cerdulatinib (PRT062070) is a selective Tyk2 inhibitor with an IC 50 of 0.5 nM. Cerdulatinib (PRT062070) also is a dual JAK and SYK inhibitor with IC 50 s of 12, 6, 8 and 32 for JAK1, 2, 3 and SYK, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRT062070; PRT2070. CAS No. 1198300-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15999.
Cerdulatinib
Cerdulatinib, also known as PRT2070 and PRT062070, is a novel, oral, dual spleen tyrosine kinase (Syk) and janus kinase (JAK) inhibitor. Cerdulatinib preferentially inhibited JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types. IL2 mediated STAT5 Y694 was inhibited with an IC50 of 0.27uM, while IL4 mediated signaling to STAT6 Y641 and functional responses in B cells and monocytes, namely CD69, CD25, and CD23 up-regulation, were inhibited with IC50 within the range of 0.11uM to 0.57uM. It is currently being studied in patients with genetically-defined hematologic cancers, as well as for patients who have failed therapy due to relapse or acquired mutations. Synonyms: Cerdulatinib; PRT2070; PRT-2070; PRT 2070; PRT-062070; PRT 062070; PRT062070. CAS No. 1198300-79-6. Molecular formula: C20H27N7O3S. Mole weight: 445.542.
Cerdulatinib HCl
Cerdulatinib is a dual SYK/JAK inhibitor. It significantly reduces cell viability in a subset of NHL cell lines, and induces apoptosis in BCR-signaling competent NHL cell lines. Synonyms: Cerdulatinib hydrochloride; PRT2070 hydrochloride; 4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide hydrochloride. Grades: >98%. CAS No. 1369761-01-2. Molecular formula: C20H28ClN7O3S. Mole weight: 482.
Cerdulatinib hydrochloride
Cerdulatinib hydrochloride (PRT062070) is a selective, oral active and reversible ATP-competitive inhibitor of dual SYK and JAK , with IC 50 s of 32 nM, 0.5 nM, 12 nM, 6 nM and 8 nM for SYK and Tyk2 , JAK1 , 2 , 3 , respectively. Cerdulatinib hydrochloride could be used to research autoimmune disease and B-cell malignancies [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRT062070 hydrochloride; PRT2070 hydrochloride. CAS No. 1369761-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15999A.