A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
The polymer product is a polymer that is derived from natural sources, with or without chemical modification. Group: Natural polymers and biopolymers. Alternative Names: Cellulose propionate, Propionyl cellulose. CAS No. 9004-48-2. Molecular formula: average Mn ~70,000 average Mw ~130,000. CCC (=O)OC[C@H]1O[C@@H] (OC (=O)CC)[C@H] (OC (=O)CC)[C@@H] (OC (=O)CC)[C@@H]1O[C@@H]2O[C@H] (COC (=O)CC)[C@@H] (OC (=O)CC)[C@H] (OC (=O)CC)[C@H]2OC (=O)CC. 1S/C36H54O19/c1-9-21 (37)45-17-19-29 (49-23 (39)11-3)31 (50-24 (40)12-4)34 (53-27 (43)15-7)36 (48-19)55-30-20 (18-46-22 (38)10-2)47-35 (54-28 (44)16-8)33 (52-26 (42)14-6)32 (30)51-25 (41)13-5/h19-20, 29-36H, 9-18H2, 1-8H3/t19-, 20-, 29-, 30-, 31+, 32+, 33-, 34-, 35+, 36+/m1/s1. DQEFEBPAPFSJLV-WLTGXWPBSA-N.
Cellulose sulfate sodium salt
Cellulose sulfate sodium salt is a critically significant compound within the realm of biomedical sciences, standing as an avant-garde solution catering to the research of paramount viral afflictions such as HIV/AIDS and various sexually transmitted diseases. Synonyms: Sodium cellulose sulfate; Kelco SCS; Cellulose, hydrogen sulfate, sodium salt; Cellulose sodium sulfate; SCS; Sodium cellulosesulfonate; SS Cellulose; Ushercell. CAS No. 9005-22-5.
cellulose synthase (GDP-forming)
Involved in the synthesis of cellulose. A similar enzyme [EC 2.4.1.12, cellulose synthase (UDP-forming)] utilizes UDP-glucose. Group: Enzymes. Synonyms: cellulose synthase (guanosine diphosphate-forming); cellulose synthetase; guanosine diphosphoglucose-1,4-β-glucan glucosyltransferase; guanosine diphosphoglucose-cellulose glucosyltransferase; GDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.29. CAS No. 9027-18-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2523; cellulose synthase (GDP-forming); EC 2.4.1.29; 9027-18-3; cellulose synthase (guanosine diphosphate-forming); cellulose synthetase; guanosine diphosphoglucose-1,4-β-glucan glucosyltransferase; guanosine diphosphoglucose-cellulose glucosyltransferase; GDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase. Cat No: EXWM-2523.
cellulose synthase (UDP-forming)
Involved in the synthesis of cellulose. A similar enzyme utilizes GDP-glucose [EC 2.4.1.29 cellulose synthase (GDP-forming)]. Group: Enzymes. Synonyms: UDP-glucose-β-glucan glucosyltransferase; UDP-glucose-cellulose glucosyltransferase; GS-I; β-1,4-glucosyltransferase; uridine diphosphoglucose-1,4-β-glucan glucosyltransferase; β-1,4-glucan synthase; β-1,4-glucan synthetase; β-glucan synthase; 1,4-β-D-glucan synthase; 1,4-β-glucan synthase; glucan synthase; UDP-glucose-1,4-β-glucan glucosyltransferase; uridine diphosphoglu. Enzyme Commission Number: EC 2.4.1.12. CAS No. 9027-19-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2345; cellulose synthase (UDP-forming); EC 2.4.1.12; 9027-19-4; UDP-glucose-β-glucan glucosyltransferase; UDP-glucose-cellulose glucosyltransferase; GS-I; β-1,4-glucosyltransferase; uridine diphosphoglucose-1,4-β-glucan glucosyltransferase; β-1,4-glucan synthase; β-1,4-glucan synthetase; β-glucan synthase; 1,4-β-D-glucan synthase; 1,4-β-glucan synthase; glucan synthase; UDP-glucose-1,4-β-glucan glucosyltransferase; uridine diphosphoglucose-cellulose glucosyltransferase; UDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase. Cat No: EXWM-2345.
Cellulose triacetate
It is widely used in the sustained-release applications and taste masking in pharmaceutical formulatiosn. Synonyms: Cellulose Triacetate Polymer; 2,3,6-Tri-O-acetyl Cellulose; Acetate Flake L 30. CAS No. 9012-9-3.
Cellulose triacetate
Cellulose triacetate is a compound produced from a source of cellulose and acetate (usually acetic anhydride). Triacetates are commonly used in the manufacture of fibers and film bases. It is chemically similar to cellulose acetate. Its distinguishing feature is that in triacetate, at least 92% of the hydroxyl groups are acetylated. During the production of triacetate, cellulose is fully acetylated; in normal cellulose acetate or cellulose diacetate, it is only partially acetylated. The heat resistance of triacetate is significantly higher than that of cellulose acetate. Uses: Plastic film base field: raw material for photographic film base (or film), special film such as x-ray, film base and insulating film separator. aerospace and aerospace materials: materials such as membranes and solid propellant cladding. reverse osmosis membrane: when the acetic acid content is 52.33% ~ 55.95%, cellulose acetate can produce a membrane with excellent performance. Group: Polymers. CAS No. 9012-9-3. Molecular formula: 966.84 g/mol. Mole weight: C6H7O2(OOCH3)3.
CELLULOSE TRIBENZOATE
CELLULOSE TRIBENZOATE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CELLULOSE TRIBENZOATE;TRIBENZOYLCELLULOSE;TRIBENZOYLCELLULOSE SUSPENSION, 10-20 UM;cellulose tribenzoate suspension;tribenzoylcellulose suspension. Product Category: Heterocyclic Organic Compound. CAS No. 37361-36-7. Product ID: ACM37361367. Alfa Chemistry ISO 9001:2015 Certified.
CEM114
CEM114 is a potent chemical epigenetic modifier (CEM) that recruits endogenous chromatin machinery through the CRISPR-Cas9 systems. Synonyms: AKOS040757520; 2279062-54-1. CAS No. 2279062-54-1. Molecular formula: C84H122FN9O19S. Mole weight: 1612.98.
Cemadotin
Cemadotin is a synthetic analogue of Dolastatin 15 with potent antiproliferative and preclinical antitumor activity. It is also a promising cancer chemotherapeutic agent. Synonyms: LU 103793; LU-103793; LU103793; NSC D-669356; N,N-dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-L-prolinebenzylamide. CAS No. 159776-69-9. Molecular formula: C35H56N6O5. Mole weight: 640.87.
cembrene A synthase
Requires Mg2+. Isolated from the bacterium Streptomyces sp. SANK 60404. This trifunctional enzyme, which contains a [4Fe-4S] cluster, also produces (R)-nephthenol and (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol. See EC 4.2.3.149, nephthenol synthase and EC 4.2.3.151, pentamethylcyclopentadecatrienol synthase. Group: Enzymes. Synonyms: DtcycB (gene name). Enzyme Commission Number: EC 4.2.3.150. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5165; cembrene A synthase; EC 4.2.3.150; DtcycB (gene name). Cat No: EXWM-5165.
cembrene C synthase
Requires Mg2+. Isolated from the bacterium Streptomyces sp. SANK 60404. This bifunctional enzyme also produces (R)-nephthenol. See EC 4.2.3.149, nephthenol synthase. Group: Enzymes. Synonyms: DtcycA (gene name). Enzyme Commission Number: EC 4.2.3.148. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5162; cembrene C synthase; EC 4.2.3.148; DtcycA (gene name). Cat No: EXWM-5162.
Cement Alumina 65997-16-2
Cement Alumina - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Cement White 65997-15-1
Cement White - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Cemiplimab
Cemiplimab is a PD-1 monoclonal antibody that blocks PD-1/PD-L1-mediated T-cell suppression. Cemiplimab has been approved for the treatment of metastatic cutaneous squamous cell carcinoma (CSCC). Synonyms: Libtayo. CAS No. 1801342-60-8.
Cemiplimab
Cemiplimab (Anti-Human PD-1) is a high-affinity programmed death receptor-1 ( PD-1 ) monoclonal IgG4 antibody that blocks PD-1/PD-L1-mediated T-cell suppression. Cemiplimab is commonly used in squamous cell skin cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1801342-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99203.
CeMMEC1
CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1; 440662-09-9; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxoisoquinoline-4-carboxamide; Oprea1_520920; SCHEMBL20942542; BCP19839; EX-A1815; EiM08-22966; AKOS005754739; AC-35499; MS-25094; HY-111445; CS-0040872; Z1863671528; N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-2-METHYL-1-OXO-1,2-DIHYDRO-4-ISOQUINOLINECARBOXAMIDE. Grade: ≥98%. CAS No. 440662-09-9. Molecular formula: C19H16N2O4. Mole weight: 336.3.
CeMMEC13
CeMMEC13 is an isoquinolinone and a potent inhibitor of TAF1 bromodomain with IC50 of 2.1 μM. It acts on the bromodomain of TAF1 but does not bind to bromodomains of BRD4, BRD9, or CREBBP. CeMMEC13 synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC13; 1790895-25-8; 1-Methyl-2-oxo-1,2-dihydro-quinoline-4-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide; CHEMBL4871450; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-2-oxoquinoline-4-carboxamide; SCHEMBL20942221; BCP25037; EX-A1816; BDBM50572136; s8329; AKOS027600530; CeMMEC13, >=98% (HPLC); CCG-267868; AC-35506; BS-15617; HY-101088; CS-0020799; C73404; A924884; Z441586532; N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-1-methyl-2-oxo-4-quinolinecarboxamide. Grade: ≥98%. CAS No. 1790895-25-8. Molecular formula: C19H16N2O4. Mole weight: 336.3.
CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1 HCl. Grade: ≥98%. CAS No. 2095432-53-2. Molecular formula: C19H17ClN2O4. Mole weight: 372.8.
Cemsidomide
Cemsidomide (CFT7455) is a ubiquitin ligase pathway Ikaros / Aiolos degrader with molecular glue activity [1]. Cemsidomide has a GI 50 of 0.05 nM for NCIH929.1 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CFT7455. CAS No. 2504235-67-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144841.
Cendakimab
Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC 50 s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RPC 4046; ABT 308; CC-93538. CAS No. 2151032-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99496.
Cendakimab
Cendakimab is a humanized monoclonal antibody directed against IL-13. Cendakimab targets IL-13 and inhibits its binding to both IL-13-receptor specific subtypes (IL-13-Rα1 and IL-13-Rα2). Cendakimab has been used in the research of eosinophilic esophagitis. Synonyms: RPC-4046; RPC 4046; RPC4046; ABT-308; ABT 308; ABT308; CC-93538; CC 93538; CC93538. Grade: 95%. CAS No. 2151032-62-9.
Cenderitide
Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B , activates the second messenger cGMP , suppresses aldosterone , and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 507289-11-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3624.
Cenegermin
Cenegermin is a recombinant human nerve growth factor that has the healing effect on eye and repair corneal damage. It was granted orphan drug designation in 2015. Uses: Repair corneal damage. CAS No. 1772578-74-1. Molecular formula: C583H908N166O173S8. Mole weight: 13266.94.
Cenerimod
Cenerimod is an active Lysosphingolipid receptor agonist originated by Actelion Pharmaceuticals and EC50 value is 2.7 nM. It is a S1P1/EDG1 receptor agonist and has a long-lasting immunomodulating effect through reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion. Cenerimod is in phase I/II clinical trials for the treatment of Systemic lupus erythematosus. Uses: Systemic lupus erythematosus. Synonyms: ACT-334441; ACT334441; ACT 334441; (S)-3-(4-(5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl)-2-ethyl-6-methylphenoxy)propane-1,2-diol. Grade: 98%. CAS No. 1262414-04-9. Molecular formula: C25H31N3O5. Mole weight: 453.54.
Cenerimod
Cenerimod (ACT-334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC 50 of 1 nM. Cenerimod shows more than 36 fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC 50 s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-334441. CAS No. 1262414-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17606.
Cenicriviroc
Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-652; TBR-652. CAS No. 497223-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14882.
Cenicriviroc
Cenicriviroc (TAK-652) is an orally active, dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cenicriviroc;TAK652. Product Category: Inhibitors. CAS No. 497223-25-3. Mole weight: 0. Purity: 0.9901. Product ID: ACM497223253. Alfa Chemistry ISO 9001:2015 Certified.
Cenicriviroc
Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Uses: Ccr2 receptor antagonists; ccr5 receptor antagonists. Synonyms: (S,E)-8-(4-(2-Butoxyethoxy)phenyl)-1-isobutyl-N-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydrobenzo[b]azocine-5-carboxamide; TAK-652; TAK652; TAK 652; TBR-652; TBR 652; TBR652; Cenicriviroc. Grade: ≥98%. CAS No. 497223-25-3. Molecular formula: C41H52N4O4S. Mole weight: 696.95.
Cenicriviroc mesylate
Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell as an experimental drug candidate for the treatment of HIV infection. Synonyms: TAK-652 mesylate; TAK 652 mesylate; TBR-652 mesylate; TBR 652 mesylate. Grade: 99.04%. CAS No. 497223-28-6. Molecular formula: C42H56N4O7S2. Mole weight: 793.051.
Cenicriviroc Mesylate
Cenicriviroc Mesylate (TAK-652 Mesylate) is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2, and displays potent anti-inflammatory and antiinfective activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-652 Mesylate; TBR-652 Mesylate. CAS No. 497223-28-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14882A.
Cenicriviroc Sulfone
Cenicriviroc Sulfone is a derivative of Cenicriviroc which is an experimental drug candidate for the treatment of HIV infection. It is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell. Synonyms: 8-[4-(2-Butoxyethoxy)phenyl]-1,2,3,4-tetrahydro-1-(2-methylpropyl)-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfonyl]phenyl]-1-benzazocine-5-carboxamide; 8-[4-(2-Butoxyethoxy)phenyl]-1-isobutyl-N-[4-[[(1-propyl-1H-imidazol-5-yl)methyl]sulfonyl]phenyl]-1. Grade: > 95%. CAS No. 497223-22-0. Molecular formula: C41H52N4O5S. Mole weight: 712.96.
Cenisertib
R763 is an orally bioavailable, synthetic, small-molecule multi-Aurora kinase inhibitor with potential antineoplastic activity. Aurora kinase inhibitor R763 selectively binds to and inhibits multiple Aurora kinases (AKs), which may result in the inhibition of cell division and proliferation, and the induction of apoptosis in tumor cells that overexpress AKs. Overexpressed in certain tumor cell types, AKs, a family of serine-threonine kinases, are important regulators of cell division and proliferation that are involved in controlling chromatid segregation. Synonyms: AS703569; AS 703569; AS-703569; R763; R 763; R-763. CAS No. 871357-89-0. Molecular formula: C24H30FN7O. Mole weight: 451.55.
Cenisertib
Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3. Cenisertib induces major growth-inhibitory effects by blocking the activity of several different molecular targets in neoplastic mast cells (MC). Cenisertib inhibits tumor growth in xenograft models of pancreatic, breast, colon, ovarian, and lung tumors and leukemia[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AS-703569; R-763. CAS No. 871357-89-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13072.
Cenobamate
Cenobamate, a sodium channel blocker, enhances GABAergic transmission and has the potential to be a versatile CNS drug. Alternative Names: (1R)-1-(2-chlorophenyl)-2-(2H-tetrazol-2-yl)ethyl carbamate;Xcopri;YKP 3089. CAS No. 913088-80-9. Product ID: API913088809. Molecular formula: C10H10ClN5O2. Mole weight: 267.67. SMILES: C1=CC=C(C(=C1)[C@H](CN2N=CN=N2)OC(=O)N)Cl. Category: Sedation & Hypnosis APIs.
CENP-F Antibody Panel, CENP-F (aa3150-3200) Control Peptide
CENP-F Antibody Panel, CENP-F (aa3150-3200) Control Peptide. Group: Molecular Biology. Grades: Affinity Purified. Pack Sizes: 1x100ul. US Biological Life Sciences.
Worldwide
Censavudine
Censavudine is a nucleoside reverse transcriptase inhibitor. It is active against HIV resistant to both abacavir and tenofovir. It is a candidate for people with multi-drug resistant (MDR) strains of the virus. It is a derivative of stavudine (d4T), but is less toxic. It has demonstrated potent in vitro activity against HIV-2. It was developed by Bristol Myers-Squibb and in clinic phase 2 trials. Uses: Censavudine is active against hiv resistant to both abacavir and tenofovir. Synonyms: OBP-601; OBP601; OBP 601; BMS-986001; BMS 986001; BMS986001; festinavir; 4'-Ed4T; 2',3'-Didehydro-3'-deoxy-4'-ethynylthymidine; 4'-Ethynyl D4T. Grade: 95%. CAS No. 634907-30-5. Molecular formula: C12H12N2O4. Mole weight: 248.24.
Censavudine
Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor. Censavudine is a potent HIV inhibitor with EC50 ranges from 30 nM to 81 nM and 450 nM to 890 nM for HIV-2 and HIV-1, respectively[1][2]. Censavudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Festinavir; BMS-986001; OBP-601. CAS No. 634907-30-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16776.
Centanafadine
Centanafadine is a dual norepinephrine-dopamine transporter inhibitor used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Synonyms: EB-1020 free base; DOV 216,419 free base; (1R,5S)-(+)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane. CAS No. 924012-43-1. Molecular formula: C15H15N. Mole weight: 209.29.
Centanafadine
Centanafadine is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC 50 s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EB-1020. CAS No. 924012-43-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16736.
Centanafadine hydrochloride
Centanafadine (hydrochloride) is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC 50 s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EB-1020 hydrochloride. CAS No. 923981-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16736A.
Centanafadine Hydrochloride
Centanafadine Hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) used as a treatment for attention deficit hyperactivity disorder (ADHD) which is in phase II clinical trials. Synonyms: DOV 216419 Hydrochloride; EB 1020 Hydrochloride; (1R,5S)-1-(2-Naphthalenyl)-3-azabicyclo[3.1.0]hexane Hydrochloride. CAS No. 923981-14-0. Molecular formula: C15H16ClN. Mole weight: 245.75.
Centanafadine Lactam
Centanafadine Lactam is an impurity or metabolite of Centanafadine, which is a dual norepinephrine-dopamine transporter inhibitor used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Synonyms: (1S,5R)-5-(2-Naphthyl)-3-azabicyclo[3.1.0]hexan-2-one; 3-Azabicyclo[3.1.0]hexan-2-one, 5-(2-naphthalenyl)-, (1S,5R)-. Molecular formula: C15H13NO. Mole weight: 223.27.
Centaurein
Centaurein. Uses: Designed for use in research and industrial production. Additional or Alternative Names: centaurein;2-(3-Hydroxy-4-methoxyphenyl)-3,6-dimethoxy-4-oxo-5-hydroxy-4H-1-benzopyran-7-yl β-D-glucopyranoside;3,6,4'-Trimethoxy-5,3'-dihydroxy-7-(β-D-glucopyranosyloxy)flavone;7-(β-D-Glucopyranosyloxy)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimeth. Product Category: Heterocyclic Organic Compound. CAS No. 35595-03-0. Molecular formula: C24H26O13. Mole weight: 522.456. Product ID: ACM35595030. Alfa Chemistry ISO 9001:2015 Certified. Categories: Centaurin, alpha 1.
Centella Asiatica Extract
Centella asiatica extract is prepared from a small herbaceous annual plant of the family mackinlayaceae, which native to India, Sri Lanka, China, and other parts of Asia. The main active ingredient of centella asiatica extract, also known as gotu kola extract is asiaticoside and asiatic acid. Centella asiatica extract is widely used to heal wounds, treat skin conditions, improve mental clarity, treat varicose veins and chronic venous insufficiency. Group: Others. Mole weight: 959.12. Centella Asiatica Extract; Centella Asiatica (Linn.) Urban. Cat No: EXTC-024.
Centella Asiatica Extract
diminish inflammation, pore cleanser, emulsifying; suitable for any skin. Uses: Designed for use in research and industrial production. Product Category: Material of cosmetics. Appearance: brown yellow to white fine powder. CAS No. 84696-21-9. Product ID: ACM84696219. Alfa Chemistry ISO 9001:2015 Certified.
Centhaquin
Centhaquine (Centhaquin; PMZ-2010) is a novel agent has the potential for treatment of haemorrhagic shock. Centhaquine (Centhaquin; PMZ-2010) can augment cardiac output, reduce systemic vascular resistance in haemorrhagic models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Centhaquine; PMZ-2010. CAS No. 57961-90-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106690.
Centhaquine
Centhaquin is a new type of drug with the potential to treat hemorrhagic shock. Synonyms: Centhaquin; Compound-7173; PMZ-2010; PMZ-2010. Grade: 98%. CAS No. 57961-90-7. Molecular formula: C22H25N3. Mole weight: 331.5.
Centrinone, a pyrimidinamine derivative, has been found to be a high affinity and selective PLK4 inhibitor (Ki = 0.16 nM). Synonyms: Centrinone; LCR-263; LCR 263; LCR263. 2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine. Grade: ≥98% by HPLC. CAS No. 1798871-30-3. Molecular formula: C26H25F2N7O6S2. Mole weight: 633.65.
Centrinone
Centrinone (LCR-263) is a selective and reversible inhibitor of polo-like kinase 4 (PLK4) with a Ki of 0.16 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCR-263. CAS No. 1798871-30-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18682.
Centrinone B
Centrinone B, has been found to be a high affinity and selective PLK4 inhibitor (Ki: 0.6 nM) and exhibit more than 2000-fold selectivity for PLK4 over Aurora A and Aurora B. Synonyms: Centrinone-B; Centrinone B; CentrinoneB; LCR-323; LCR 323; LCR323; 2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine. Grade: ≥98% by HPLC. CAS No. 1798871-31-4. Molecular formula: C27H27F2N7O5S2. Mole weight: 631.67.
Centrinone-B
Centrinone-B (LCR-323) is a potent and highly selective PLK4 inhibitor, with a Ki of 0.59 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCR-323. CAS No. 1798871-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18683.
Centriolin (2174-2182)
A peptide fragment of Centriolin which is a centrosomal protein required for the centrosome to function as a microtubule organizing center.
Centrocin 1
Centrocin 1 is isolated from Strongylocentrotus droebachiensis. It has antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and against fungi with minimum inhibitory concentration (MIC) between 0.78 μM and 50 μM. Centrocin 1 shows little hemolytic activity even at a concentration of 100 μM.
Centrocin 2
Centrocin 2 is isolated from Strongylocentrotus droebachiensis. It has antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and against fungi with minimum inhibitory concentration (MIC) between 0.78 μM and 50 μM. Centrocin 2 shows little hemolytic activity at concentrations up to 12.5 μM but >50% lysis at 100 μM.
Centrosome-associated protein 350 (2297-2305) is a truncated fragment of CEP350. CEP350 is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. It primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Synonyms: CEP350 (2297-2305).
Cenupatide
Cenupatide is an inhibitor of urokinase plasminogen activator receptor (uPAR). CAS No. 1006388-38-0. Molecular formula: C28H47N11O5. Mole weight: 617.76.
CEP-11981 is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR) and Tie2 receptor tyrosine kinases with potential antiangiogenic and antineoplastic activities. Pan-VEGFR/Tie2 tyrosine kinase inhibitor CEP-11981 selectively binds to VEGFR and Tie2 receptor tyrosine kinases, which may result the inhibition of endothelial cell migration, proliferation and survival and the inhibition of tumor cell proliferation and tumor cell death. VEGFR and Tie2 are frequently overexpressed by a variety of tumor cell types and play crucial roles in the regulation of angiogenesis and the maintenance of tumor blood vessels. Tie2 (tyrosine kinase with immunoglobulin-like and EGF-like domains) is activated by angiopoietin-1 (Ang-1). Synonyms: CEP-11981; CEP 11981; CEP11981. CAS No. 856691-93-5. Molecular formula: C28H27N7O. Mole weight: 477.57.
CEP-11981
CEP-11981(ESK981; BOL 303213X) is an orally active tyrosine kinase inhibitor (TKI), which can target TIE2, VEGFR1-3 and FGFR1, and has potential anti-tumor and anti-angiogenic effects[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ESK981; BOL 303213X. CAS No. 856691-93-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16135.
CEP 1347
Inhibitor of c-jun N-terminal kinase (JNK) signaling. Rescues motor neurons undergoing apoptosis (EC50 = 20nM). Blocks A β-induced cortical neuron apoptosis (EC50 ~51nM). Does not inhibit ERK1 activity. Neuroprotective. Group: Biochemicals. Alternative Names: (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester. Grades: Highly Purified. CAS No. 156177-65-0. Pack Sizes: 1mg. Molecular Formula: C33H33N3O5S2.1?2H2O, Molecular Weight: 624.77. US Biological Life Sciences.
Worldwide
CEP 1347
CEP 1347, also named KT 7515 or CHEMBL290352, an ethylthiomethyl derivative, is a potent, selective inhibitor of the cJun-amino terminal kinase pathway currently under clinical evaluation for the treatment of neurodegenerative diseases. It blocks Aβ-induced cortical neuron apoptosis (EC50 ~51 nM). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CHEMBL290352; CEP-1347; 3,9-Bis(etsm)-K-252a; CEP1347; 156177-65-0; CEP 1347; KT7515; 3,9-Bis((ethylthio)methyl)-K-252a; KT 7515; KT-7515; GTPL8173; SCHEMBL12047710; BDBM24942; CEP1374; CEP 1374; CEP-1374; ZINC3928304; AKOS024458422; KT-1575; 170587-65-2; 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 5,16-bis((ethylthio)methyl)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9S-(9alpha,10beta,12alpha))-; CEP 1347|(9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester; methyl (15S,16R,18R)-10,23-bis[(ethylsulfanyl)methyl]-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate. CAS No. 156177-65-0. Molecular formula: C33H33N3O5S2. Mole weight: 615.76.
CEP-1347
CEP-1347 is an inhibitor of the JNK/SAPK pathway with neuroprotective effects. CEP-1347 blocks JNK1 activation induced by members of the mixed lineage kinase (MLK) family (MLK3, MLK2, MLK1, dual leucine zipper kinase, and leucine zipper kinase). As an inhibitor of MDM4 , CEP-1347 can more effectively inhibit the growth of glioma cells expressing wild-type p53 [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KT7515. CAS No. 156177-65-0. Pack Sizes: 1 mg. Product ID: HY-10412.
CEP-14083
CEP-14083 is a ALK inhibitor. It has a potent activity against ALK in enzymatic assays (IC50 = 11 nmol/L). CEP-14083 can also inhibit the insulin receptor at a concentration within a nanomolar range. In a preclinical assay, CEP-14083 showed it can control the expression of molecules that determine T-cell identity and signaling in lymphoma cells. Synonyms: CEP14083; CEP 14083; CEP-14083. 1-methyl-3-(4-methyl-6-oxo-13-propyl-2,4,6,7,8,13-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-10-yl)-1-phenylurea. Grade: 98%. CAS No. 856692-39-2. Molecular formula: C31H30N6O2. Mole weight: 518.61.
CEP-14513
CEP-14513 is a ALK inhibitor. It shows ALK inhibitory activity in both in vitro enzymatic assay (IC50 = 5 nM) and cell-based assays of ALK tyrosine phosphorylation (IC50 = 30 nM). Synonyms: CEP14513; CEP 14513; CEP-14513. 13-isobutyl-4-methyl-6-oxo-2,4,6,7,8,13-hexahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-10-yl 4-(dimethylamino)benzylcarbamate. Grade: 98%. CAS No. 856693-04-4. Molecular formula: C34H36N6O3. Mole weight: 576.69.
CEP-1612
CEP-1612, a dipeptidyl proteasome inhibitor, induces apoptosis and inhibits tumor growth of the human lung cancer cell line A-549 in an in vivo model. Synonyms: N-[(2S)-5-[[amino(nitramido)methylidene]amino]-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-2-cyclopentyl-10-(1,3-dioxoisoindol-2-yl)decanamide; CEP-1612; CEP 1612; CEP1612; UNII-9K6U075027. Grade: >98%. CAS No. 189036-01-9. Molecular formula: C35H53N7O7. Mole weight: 683.84.