A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Darexaban (YM150) is a potent, selective and orally active factor Xa (FXa) inhibitor with an IC 50 of 54.6 nM. Darexaban shows high selectivity against other related serine proteases, such as trypsin, thrombin, and kallikrein. Darexaban has anticoagulant and antithrombotic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM150. CAS No. 365462-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14853.
Darexaban Maleate
Diazepane derivative used in the preparation of inhibitors of activated blood coagulation factor X. Group: Biochemicals. Alternative Names: N-[2-[[4-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-hydroxyphenyl]-4-methoxybenzamide (2Z)-2-Butenedioate. Grades: Highly Purified. CAS No. 365462-24-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
D-Arg(8)-AVP
D-Arg(8)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Arg(8)-Vasopressin; D-Arg-AVP; Vasopressin, 8-D-arginine-; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide; 8-D-Argininevasopressin; D-Arginine-vasopressin; (D-Arg8)vasopressin. CAS No. 5591-81-1. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-arginase
D-arginase (EC 3.5.3.10) is an enzyme with systematic name D-arginine amidinohydrolase. Group: Enzymes. Enzyme Commission Number: EC 3.5.3.10. CAS No. 37289-14-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4512; D-arginase; EC 3.5.3.10; 37289-14-8. Cat No: EXWM-4512.
D-Arginine
D-Arginine. Group: Biochemicals. Grades: Highly Purified. CAS No. 157-06-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
D-Arginine
Arginine (Arg) is a dibasic amino acid and exists as two enantiomers: D-Arg and L-Arg. D-Arg is a cationic endogenous amino acid and is found in the central nervous system. Uses: D-arginine has been used: as an organic substrate to study the metabolic versatility of freshwater sedimentary archaea feeding on different organic carbon sources to study its role in the inhibition of pseudorabies virus (prv) plaque formation by arginase as a reference standard for chromatographic separation. Additional or Alternative Names: (R)-2-Amino-5-guanidinopentanoic acid. Product Category: Amino Acids. CAS No. 157-06-2. Molecular formula: H2NC(=NH)NH(CH2)3CH(NH2)CO2H. Mole weight: 174.2. Canonical SMILES: N[C@H](CCCNC(N)=N)C(O)=O. ECNumber: 205-866-5. Product ID: ACM157062-1. Alfa Chemistry ISO 9001:2015 Certified.
D-Arginine 99+%
D-Arginine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
D-Arginine amide dihydrochloride 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. CAS No. 203308-91-2. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
D-arginine dehydrogenase
Contains a non-covalent FAD cofactor. The enzyme, which has been isolated from the bacterium Pseudomonas aeruginosa PAO1, is a catabolic enzyme that is part of a two-enzyme complex involved in the racemization of D and L-arginine. The enzyme has a broad substrate range and can act on most D-amino acids with the exception of D-glutamate and D-aspartate. However, activity is maximal with D-arginine and D-lysine. Not active on glycine. Group: Enzymes. Synonyms: D-amino-acid:(acceptor) oxidoreductase (deaminating); D-amino-acid dehydrogenase; D-amino-acid:acceptor oxidoreductase (deaminating). Enzyme Commission Number: EC 1.4.99.6. CAS No. 37205-44-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1492; D-arginine dehydrogenase; EC 1.4.99.6; 37205-44-0; D-amino-acid:(acceptor) oxidoreductase (deaminating); D-amino-acid dehydrogenase; D-amino-acid:acceptor oxidoreductase (deaminating). Cat No: EXWM-1492.
D-Arginine monohydrochloride. Uses: D-arginine attenuates increased arginase expression, oxidative stress, endothelial dysfunction, and advanced glycation endproducts formation induced by methylgloxyl and high glucose. this attenuation by d-arginine is thought to occur through an endothelial nos independent mechanism. Product Category: Amino Acids. CAS No. 627-75-8. Mole weight: 210.66. Canonical SMILES: Cl.N[C@H](CCCNC(N)=N)C(O)=O. ECNumber: 211-010-1. Product ID: ACM627758-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: D-Arginine hydrochloride.
D-Arginine,n2-[(1,1-dimethylethoxy)carbonyl]-,monohydrochloride,monohydrate(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(TERT-BUTOXYCARBONYL)-D-ARGININE-HYDROCHLORIDE;NALPHA-BOC-D-ARGININE HYDROCHLORIDE HYDRATE;N-ALPHA-BOC-D-ARGININE HYDROCHLORIDE SALT MONOHYDRATE;N-BOC-D-ARGININE HYDROCHLORIDE HYDRATE;N-ALPHA-T-BOC-D-ARGININE HYDROCHLORIDE HYDRATE;NALPHA-(TERT-BUTOXYCA. Product Category: Heterocyclic Organic Compound. CAS No. 204070-00-8. Molecular formula: C11H22N4O4.ClH.H2O. Mole weight: 328.79. Purity: 0.96. IUPACName: (2R)-5-(diaminomethylideneamino)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid;hydrate;hydrochloride. Canonical SMILES: CC(C)(C)OC(=O)NC(CCCN=C(N)N)C(=O)O.O.Cl. Product ID: ACM204070008. Alfa Chemistry ISO 9001:2015 Certified.
Darglitazone is a thiazolidinedione (TZD) which is a proliferator-activated receptor γ (PPARγ) agonist. It increases the sensitivity of cells to insulin, stimulating insulin-induced PI3K activity at submicromolar concentrations by increasing the expression of the p85 subunit of PI3K. Synonyms: CP 86325. Grades: ≥95%. CAS No. 141200-24-0. Molecular formula: C23H20N2O4S. Mole weight: 420.5.
Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. Darifenacin hydrobromide has 9 and 12-fold greater affinity for M3 compared to M1 and M5, respectively, and 59-fold greater affinity for M3 compared to both M2 and M4. Darifenacin is used clinically to treat urinary incontinence and overactive bladder syndrome. Uses: Muscarinic antagonists. Synonyms: UK-88525; UK 88525; UK88525. Grades: >98%. CAS No. 133099-04-4. Molecular formula: C28H30N2O2. Mole weight: 426.55.
Darifenacin
Darifenacin (UK-88525) is a selective and orally active M3 muscarinic receptor ( M3R ) antagonist with a pKi of 8.9. Darifenacin binds >20-fold more specifically to M3R than to other muscarinic receptors. Darifenacin can be used in the study of urinary incontinence and other symptoms of overactive bladder. Darifenacin inhibits tumor growth in colorectal cancer cells and has anti-tumor effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-88525. CAS No. 133099-04-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0033.
Darifenacin Carboxylic Acid Impurity
2,3-Dihydro-5-benzofuranacetic Acid is a metabolite of Darifenacin. Synonyms: 2,3-Dihydro-5-benzofuranacetic Acid; (2,3-Dihydrobenzofuran-5-yl)acetic Acid; 2,3-Dihydrobenzofuran-5-acetic Acid; 2-(2,3-Dihydrobenzofuran-5-yl)acetic Acid. Grades: > 95%. CAS No. 69999-16-2. Molecular formula: C10H10O3. Mole weight: 178.18.
Darifenacin HBr
Darifenacin HBr. Group: Biochemicals. Alternative Names: (1-[2-(2,3-Dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl}-2,2-diphenylacetamide hydrobromide. Grades: Highly Purified. CAS No. 133099-07-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C28H30N2O2·HBr. US Biological Life Sciences.
Worldwide
Darifenacin hydrobromide
Darifenacin hydrobromide. Uses: Designed for use in research and industrial production. Product Category: Bromine Series. CAS No. 133099-07-7. Product ID: ACM133099077. Alfa Chemistry ISO 9001:2015 Certified.
Darifenacin hydrobromide
Darifenacin (UK-88525) hydrobromide is a selective and orally active M3 muscarinic receptor ( M3R ) antagonist with a pKi of 8.9. Darifenacin hydrobromide binds >20-fold more specifically to M3R than to other muscarinic receptors. Darifenacin hydrobromide can be used in the study of urinary incontinence and other symptoms of overactive bladder. Darifenacin hydrobromide inhibits tumor growth in colorectal cancer cells and has anti-tumor effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-88525 hydrobromide. CAS No. 133099-07-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0012.
Darifenacin Hydrobromide
{1-(2-(2,3-Dihydrobenzofuran-5-yl)ethyl)-3-pyrrolidnyl}-2,2-diphenylacetamide hydrobromide. CAS No. 133099-07-7. Product ID: 8-04303. Molecular formula: C28H30N2O2 HBr. Mole weight: 507.47. Purity: 0.99. Properties: white crystalline.
Darifenacin exerts non-parallel rightward displacement of the agonist curve and also significant depression of the maximum response (+)-cis-Dioxolane produced concentration-dependent contraction of the isolated bladder of rat. Uses: Muscarinic antagonists. Synonyms: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide Hydrobromide; Enablex; Emselex; (S)-2-(1-(2-(2,3-dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetamide hydrobromide. Grades: >98%. CAS No. 133099-07-7. Molecular formula: C28H30N2O2.HBr. Mole weight: 507.46.
Darifenacin Hydrobromide
Used as a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Group: Biochemicals. Alternative Names: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α-α-diphenyl-3-pyrrolidineacetamide Hydrobromide; Enablex; Emselex. Grades: Highly Purified. CAS No. 133099-07-7. Pack Sizes: 10mg. US Biological Life Sciences.
Used as a medication to treat urinary incontinence. It works by blocking the M# muscarinic acetylcholine receptor. Group: Biochemicals. Alternative Names: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-a-a-diphenyl-3-pyrrolidineacetamide Hydrobromide; Enablex; Emselex. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Darifenacin Impurity
Cas No. 1048979-09-4.
Darifenacin Impurity A
1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetic Acid is an impurity of Darifenacin, a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Synonyms: 1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetic Acid. Grades: > 95%. CAS No. 1048979-16-3. Molecular formula: C28H29NO3. Mole weight: 427.53.
Darifenacin Impurity E
4-[2-di-[2-(2,3-Dihydrobenzofuran-4-yl)ethyl]aminoethyl)-3,3-diphenylpyrolidine-2-one is a cyclic amide impurity of Darifenacin, a medication used to treat urinary incontinence. Synonyms: 4-[2-di-[2-(2,3-Dihydrobenzofuran-4-yl)ethyl]aminoethyl)-3,3-diphenylpyrolidine-2-one; Darifenacin Cyclic Amide. Grades: > 95%. CAS No. 1797983-04-0. Molecular formula: C38H40N2O3. Mole weight: 572.74.
Darifenacin Morpholine Amide Impurity
Darifenacin Morpholine Amide Impurity is an impurity of Darifenacin Morpholine Amide, a medication used for the therapy of overactive bladder syndrome. Synonyms: 2-(2,3-dihydrobenzofuran-5-yl)-1-Morpholinoethanethione. Grades: > 95%. CAS No. 97483-11-9. Molecular formula: C14H17NO2S. Mole weight: 263.36.
Darifenacin N-Oxide
Darifenacin N-Oxide is an impurity of Darifenacin, a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Synonyms: Darifenacin Impurity C. Grades: > 95%. CAS No. 1391080-40-2. Molecular formula: C28H30N2O3. Mole weight: 442.55.
Darinaparsin
Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZIO-101; S-Dimethylarsino-glutathione. CAS No. 69819-86-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14943.
Darinaparsin
Darinaparsin is a small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of action is unclear, darinaparsin, a highly toxic metabolic intermediate of inorganic arsenicals (iAs) that occurs in vivo, appears to generate volatile cytotoxic arsenic compounds when glutathione (GSH) concentrations are low. The arsenic compounds generated from darinaparsin disrupt mitochondrial bioenergetics, producing reactive oxygen species (ROS) and inducing ROS-mediated tumor cell apoptosis; in addition, this agent or its byproducts may initiate cell death by interrupting the G2/M phase of the cell cycle and may exhibit antiangiogenic effects. Compared to inorganic arsenic compounds such as arsenic trioxide (As2O3), darinaparsin appears to exhibit a wide therapeutic window. Synonyms: ZIO 101; ZIO101; ZIO-101; SP-02; SP 02; SP02; Zinapar; L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine. CAS No. 69819-86-9. Molecular formula: C12H22AsN3O6S. Mole weight: 411.31.
Darizmetinib
Darizmetinib (HRX-0215) is an orally active, potent and selective inhibitor of mitogen-activated protein kinase kinase 4 (MKK4). Darizmetinib leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration. Darizmetinib is promising for research of preventing liver failure after extensive oncological liver resections or transplantation of small liver grafts[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HRX-0215. CAS No. 2369583-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-152860.
Darlucin A
Darlucin is a diisocyanid compound produced by Darluca filum. Darlucin A has antibacterial and fungi activity, and weak cytotoxicity. CAS No. 162341-15-3. Molecular formula: C19H16N2O3. Mole weight: 320.34.
Darlucin B
Darlucin is a diisocyanid compound produced by Darluca filum. Darlucin B has antibacterial and fungi activity, and weak cytotoxicity. CAS No. 162341-16-4. Molecular formula: C19H20N2O3. Mole weight: 324.37.
Darodipine
Darodipine, also known as PY 108-068, is an antagonist of calcium channel. Synonyms: diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; darodipine; PY-108068; PY108068; PY108068; PY108-068; PY-108-068; PY 108-068; Darodipine. CAS No. 72803-02-2. Molecular formula: C19H21N3O5. Mole weight: 371.39.
Darolutamide
Darolutamide (ODM-201;BAY-1841788) is a potent androgen receptor ( AR ) antagonist with an IC 50 of 26 nM in in vitro assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ODM-201; BAY-1841788. CAS No. 1297538-32-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16985.
Darovasertib
Darovasertib (LXS196) is a potent, selective and orally active protein kinase C ( PKC ) inhibitor, with IC 50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LXS196; IDE196. CAS No. 1874276-76-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101569.
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H37N3O7S. CAS No. 206361-99-1. Prepack ID 90027035-25mg. Molecular Weight 547.66. See USA prepack pricing.
Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC 50 = 0.003 μM; IC 90 = 0.009 μM) with minimal cytotoxicity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC114; UIC-94017. CAS No. 206361-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17040.
Darunavir
Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively. Uses: Hiv protease inhibitors. Synonyms: TMC-114; TMC 114; TMC114; Prezista. Grades: ≥98%. CAS No. 206361-99-1. Molecular formula: C27H37N3O7S. Mole weight: 547.67.
Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Alternative Names: [ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl-d9) amino]-2-hydroxy-1- (phenyl-methyl) propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester; TMC-114-d9; UIC-94017-d9. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Darunavir Ethanolate
Darunavir ethanolate (TMC114 Ethanolate) is a potent HIV protease inhibitor used to treat and prevent HIV/AIDS. Darunavir has a K i of 1 nM for wild type HIV-1 protease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC114 Ethanolate. CAS No. 635728-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17041.
Darunavir Ethanolate
Darunavir Ethanolate is a nonpeptidic HIV protease inhibitor, used to treat HIV infection. Uses: Hiv protease inhibitors. Synonyms: Phosphonoformate. Grades: >98%. CAS No. 635728-49-3. Molecular formula: C27H37N3O7S·C2H5OH. Mole weight: 593.73.
Darunavir Ethanolate
Darunavir Ethanolate. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -3-[[ (4-aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenylmethyl) propyl]carbamic Acid (3R, 3aS, 6aR)Hexahydrofuro[2, 3-b]furan-3-yl Ester compd. with Ethanol. Grades: Highly Purified. CAS No. 635728-49-3. Pack Sizes: 5mg. Molecular Formula: C29H43N3O8S, Molecular Weight: 593.73. US Biological Life Sciences.
Worldwide
Darunavir impurity 18
Darunavir impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1402142-62-4. Molecular formula: C20H29N3O3S. Mole weight: 391.53. Catalog: APB1402142624.
Darunavir Impurity 2
Darunavir Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate. CAS No. 1526916-57-3. Molecular formula: C22H31N3O5S. Mole weight: 449.56. Catalog: APB1526916573.
Darunavir impurity 3
Darunavir impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1402142-63-5. Molecular formula: C27H37N3O7S. Mole weight: 547.67. Catalog: APB1402142635.
Darunavir Impurity A
Darunavir Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide. CAS No. 169280-56-2. Molecular formula: C20H29N3O3S. Mole weight: 391.53. Catalog: APB169280562.
Darunavir N-β-D-Glucuronide
Darunavir N-β-D-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: 1-Deoxy-1-[[4-[[[ (2R, 3S) -3-[[[[ (3R, 3aS, 6aR) -hexahydrofuro[2, 3-b]furan-3-yl]oxy]carbonyl]amino]-2-hydroxy-4-phenylbutyl] (2-methylpropyl) amino]sulfonyl]phenyl]amino]-β -D-glucopyranuronic Acid. Grades: > 95%. CAS No. 1159613-25-8. Molecular formula: C33H45N3O13S. Mole weight: 723.79.
Darunavir-O-Glucuronide
Darunavir-O-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: Darunavir O-β-D-Glucuronide. Grades: > 95%. CAS No. 1159613-27-0. Molecular formula: C33H45N3O13S. Mole weight: 723.79.
Darusentan
Darusentan (Lu-135252) is a selective endothelin receptor A ( ET-A ) receptor antagonist, which binds with a K i of 1.4 nM to the ET-A receptor and a K i of 184 nM to ET-B receptor, respectively with a 100-fold selectivity for ETA rather than ETB receptors [1]. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a K i of 13 nM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu-135252. CAS No. 171714-84-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15404.
Darusentan
Darusentan is a selective endothelin-1 receptor A inhibitor. Darusentan is identified as the treatment of congestive heart failure, hypertension and cancers. It blocks endothelin ETA receptor thus results in an increase of sodium and potassium excretion in aging rats. Uses: Endothelin receptor antagonists. Synonyms: LU-135252; LU135252; LU 135252; HMR-4005; HMR 4005; HMR4005; (2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid. Grades: 95%. CAS No. 171714-84-4. Molecular formula: C22H22N2O6. Mole weight: 410.426.
Darutoside
Darutoside is a diterpenoid isolated from Siegesbeckia [1]. Uses: Scientific research. Group: Natural products. CAS No. 59219-65-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6028.
Darutoside
Darutoside. Group: Biochemicals. Alternative Names: Darutin. Grades: Plant Grade. CAS No. 59219-65-7. Pack Sizes: 20mg. Molecular Formula: C26H44O8, Molecular Weight: 484.623. US Biological Life Sciences.
Worldwide
DAS-5-oCRBN
DAS-5-oCRBN is a selective and potent PROTAC degrader of c-Src kinase. DAS-5-oCRBN has antiproliferative activity in both c-Src-dependent cell lines[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-163144.
DASA-58
DASA-58 is a potential pyruvate kinase isozyme (PKM2) allosteric activator. DASA-58 can be used for the research of metabolism and kinds of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1203494-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19330.