American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
D-Arginine monohydrochloride ?98% (TLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
D-Arginine monohydrochloride 1g Pack Size. Group: Amino Acids. Formula: C6H14N4O2 · HCl. CAS No. 627-75-8. Prepack ID 90028516-1g. Molecular Weight 210.66. See USA prepack pricing. Molekula Americas
D-Arginine,n2-[(1,1-dimethylethoxy)carbonyl]-,monohydrochloride,monohydrate(9ci) D-Arginine,n2-[(1,1-dimethylethoxy)carbonyl]-,monohydrochloride,monohydrate(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(TERT-BUTOXYCARBONYL)-D-ARGININE-HYDROCHLORIDE;NALPHA-BOC-D-ARGININE HYDROCHLORIDE HYDRATE;N-ALPHA-BOC-D-ARGININE HYDROCHLORIDE SALT MONOHYDRATE;N-BOC-D-ARGININE HYDROCHLORIDE HYDRATE;N-ALPHA-T-BOC-D-ARGININE HYDROCHLORIDE HYDRATE;NALPHA-(TERT-BUTOXYCA. Product Category: Heterocyclic Organic Compound. CAS No. 204070-00-8. Molecular formula: C11H22N4O4.ClH.H2O. Mole weight: 328.79. Purity: 0.96. IUPACName: (2R)-5-(diaminomethylideneamino)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid;hydrate;hydrochloride. Canonical SMILES: CC(C)(C)OC(=O)NC(CCCN=C(N)N)C(=O)O.O.Cl. Product ID: ACM204070008. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
D-Argininol Synonyms: H-D-Arg-ol. CAS No. 1313054-61-3. Molecular formula: C6H16N4O. Mole weight: 160.20. BOC Sciences 6
Darglitazone Darglitazone is a thiazolidinedione (TZD) which is a proliferator-activated receptor γ (PPARγ) agonist. It increases the sensitivity of cells to insulin, stimulating insulin-induced PI3K activity at submicromolar concentrations by increasing the expression of the p85 subunit of PI3K. Synonyms: CP 86325. Grades: ≥95%. CAS No. 141200-24-0. Molecular formula: C23H20N2O4S. Mole weight: 420.5. BOC Sciences 10
Darglitazone sodium salt ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
Darifenacin Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. Darifenacin hydrobromide has 9 and 12-fold greater affinity for M3 compared to M1 and M5, respectively, and 59-fold greater affinity for M3 compared to both M2 and M4. Darifenacin is used clinically to treat urinary incontinence and overactive bladder syndrome. Uses: Muscarinic antagonists. Synonyms: UK-88525; UK 88525; UK88525. Grades: >98%. CAS No. 133099-04-4. Molecular formula: C28H30N2O2. Mole weight: 426.55. BOC Sciences
Darifenacin Darifenacin (UK-88525) is a selective and orally active M3 muscarinic receptor ( M3R ) antagonist with a pKi of 8.9. Darifenacin binds >20-fold more specifically to M3R than to other muscarinic receptors. Darifenacin can be used in the study of urinary incontinence and other symptoms of overactive bladder. Darifenacin inhibits tumor growth in colorectal cancer cells and has anti-tumor effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-88525. CAS No. 133099-04-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0033. MedChemExpress MCE
Darifenacin Carboxylic Acid Impurity 2,3-Dihydro-5-benzofuranacetic Acid is a metabolite of Darifenacin. Synonyms: 2,3-Dihydro-5-benzofuranacetic Acid; (2,3-Dihydrobenzofuran-5-yl)acetic Acid; 2,3-Dihydrobenzofuran-5-acetic Acid; 2-(2,3-Dihydrobenzofuran-5-yl)acetic Acid. Grades: > 95%. CAS No. 69999-16-2. Molecular formula: C10H10O3. Mole weight: 178.18. BOC Sciences 6
Darifenacin HBr Darifenacin HBr. Group: Biochemicals. Alternative Names: (1-[2-(2,3-Dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl}-2,2-diphenylacetamide hydrobromide. Grades: Highly Purified. CAS No. 133099-07-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C28H30N2O2·HBr. US Biological Life Sciences. USBiological 7
Worldwide
Darifenacin hydrobromide Darifenacin (UK-88525) hydrobromide is a selective and orally active M3 muscarinic receptor ( M3R ) antagonist with a pKi of 8.9. Darifenacin hydrobromide binds >20-fold more specifically to M3R than to other muscarinic receptors. Darifenacin hydrobromide can be used in the study of urinary incontinence and other symptoms of overactive bladder. Darifenacin hydrobromide inhibits tumor growth in colorectal cancer cells and has anti-tumor effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-88525 hydrobromide. CAS No. 133099-07-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0012. MedChemExpress MCE
Darifenacin hydrobromide Darifenacin hydrobromide. Uses: Designed for use in research and industrial production. Product Category: Bromine Series. CAS No. 133099-07-7. Product ID: ACM133099077. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
Darifenacin Hydrobromide ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardspharmaceutical toxicology. Alternative Names: (S)-3-(Carbamoyldiphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]pyrrolidine hydrobromide, (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-alpha,alpha-diphenyl-3-pyrrolidineacetamide hydrobromide (1:1), Darifenacin hydrobromide, 3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-alpha,alpha-diphenyl-, monohydrobromide, (3S)- (9CI), UK 88525-04 hydrobromide, Enablex, Emselex, 3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-alpha,alpha-diphenyl-, monohydrobromide, (S)-, UK 88525-04, Darilong. Alfa Chemistry Analytical Products 2
Darifenacin Hydrobromide {1-(2-(2,3-Dihydrobenzofuran-5-yl)ethyl)-3-pyrrolidnyl}-2,2-diphenylacetamide hydrobromide. CAS No. 133099-07-7. Product ID: 8-04303. Molecular formula: C28H30N2O2 HBr. Mole weight: 507.47. Purity: 0.99. Properties: white crystalline. CarboMer Inc
Darifenacin Hydrobromide Used as a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Group: Biochemicals. Alternative Names: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α-α-diphenyl-3-pyrrolidineacetamide Hydrobromide; Enablex; Emselex. Grades: Highly Purified. CAS No. 133099-07-7. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
Darifenacin Hydrobromide Darifenacin exerts non-parallel rightward displacement of the agonist curve and also significant depression of the maximum response (+)-cis-Dioxolane produced concentration-dependent contraction of the isolated bladder of rat. Uses: Muscarinic antagonists. Synonyms: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide Hydrobromide; Enablex; Emselex; (S)-2-(1-(2-(2,3-dihydrobenzofuran-5-yl)ethyl)pyrrolidin-3-yl)-2,2-diphenylacetamide hydrobromide. Grades: >98%. CAS No. 133099-07-7. Molecular formula: C28H30N2O2.HBr. Mole weight: 507.46. BOC Sciences 6
Darifenacin Hydrobromide ((3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-a-a-diphenyl-3-pyrrolidineacetamide Hydrobromide;Enablex; Emselex) Used as a medication to treat urinary incontinence. It works by blocking the M# muscarinic acetylcholine receptor. Group: Biochemicals. Alternative Names: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-a-a-diphenyl-3-pyrrolidineacetamide Hydrobromide; Enablex; Emselex. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 1
Worldwide
Darifenacin Impurity Cas No. 1048979-09-4. BOC Sciences 6
Darifenacin Impurity A 1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetic Acid is an impurity of Darifenacin, a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Synonyms: 1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetic Acid. Grades: > 95%. CAS No. 1048979-16-3. Molecular formula: C28H29NO3. Mole weight: 427.53. BOC Sciences 6
Darifenacin Impurity E 4-[2-di-[2-(2,3-Dihydrobenzofuran-4-yl)ethyl]aminoethyl)-3,3-diphenylpyrolidine-2-one is a cyclic amide impurity of Darifenacin, a medication used to treat urinary incontinence. Synonyms: 4-[2-di-[2-(2,3-Dihydrobenzofuran-4-yl)ethyl]aminoethyl)-3,3-diphenylpyrolidine-2-one; Darifenacin Cyclic Amide. Grades: > 95%. CAS No. 1797983-04-0. Molecular formula: C38H40N2O3. Mole weight: 572.74. BOC Sciences 6
Darifenacin Morpholine Amide Impurity Darifenacin Morpholine Amide Impurity is an impurity of Darifenacin Morpholine Amide, a medication used for the therapy of overactive bladder syndrome. Synonyms: 2-(2,3-dihydrobenzofuran-5-yl)-1-Morpholinoethanethione. Grades: > 95%. CAS No. 97483-11-9. Molecular formula: C14H17NO2S. Mole weight: 263.36. BOC Sciences 6
Darifenacin N-Oxide Darifenacin N-Oxide is an impurity of Darifenacin, a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor. Synonyms: Darifenacin Impurity C. Grades: > 95%. CAS No. 1391080-40-2. Molecular formula: C28H30N2O3. Mole weight: 442.55. BOC Sciences 6
Darinaparsin Darinaparsin is a small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of action is unclear, darinaparsin, a highly toxic metabolic intermediate of inorganic arsenicals (iAs) that occurs in vivo, appears to generate volatile cytotoxic arsenic compounds when glutathione (GSH) concentrations are low. The arsenic compounds generated from darinaparsin disrupt mitochondrial bioenergetics, producing reactive oxygen species (ROS) and inducing ROS-mediated tumor cell apoptosis; in addition, this agent or its byproducts may initiate cell death by interrupting the G2/M phase of the cell cycle and may exhibit antiangiogenic effects. Compared to inorganic arsenic compounds such as arsenic trioxide (As2O3), darinaparsin appears to exhibit a wide therapeutic window. Synonyms: ZIO 101; ZIO101; ZIO-101; SP-02; SP 02; SP02; Zinapar; L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine. CAS No. 69819-86-9. Molecular formula: C12H22AsN3O6S. Mole weight: 411.31. BOC Sciences 11
Darinaparsin Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZIO-101; S-Dimethylarsino-glutathione. CAS No. 69819-86-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14943. MedChemExpress MCE
Darlucin A Darlucin is a diisocyanid compound produced by Darluca filum. Darlucin A has antibacterial and fungi activity, and weak cytotoxicity. CAS No. 162341-15-3. Molecular formula: C19H16N2O3. Mole weight: 320.34. BOC Sciences 5
Darlucin B Darlucin is a diisocyanid compound produced by Darluca filum. Darlucin B has antibacterial and fungi activity, and weak cytotoxicity. CAS No. 162341-16-4. Molecular formula: C19H20N2O3. Mole weight: 324.37. BOC Sciences 5
Darodipine Darodipine, also known as PY 108-068, is an antagonist of calcium channel. Synonyms: diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; darodipine; PY-108068; PY108068; PY108068; PY108-068; PY-108-068; PY 108-068; Darodipine. CAS No. 72803-02-2. Molecular formula: C19H21N3O5. Mole weight: 371.39. BOC Sciences 10
Darolutamide Darolutamide (ODM-201;BAY-1841788) is a potent androgen receptor ( AR ) antagonist with an IC 50 of 26 nM in in vitro assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ODM-201; BAY-1841788. CAS No. 1297538-32-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16985. MedChemExpress MCE
Darovasertib Darovasertib (LXS196) is a potent, selective and orally active protein kinase C ( PKC ) inhibitor, with IC 50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LXS196; IDE196. CAS No. 1874276-76-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101569. MedChemExpress MCE
Dartanol Dartanol. CAS No. 28219-61-6. VIGON Item # 504110. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. Vigon
America & Internationally
Darunavir Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively. Uses: Hiv protease inhibitors. Synonyms: TMC-114; TMC 114; TMC114; Prezista. Grades: ≥98%. CAS No. 206361-99-1. Molecular formula: C27H37N3O7S. Mole weight: 547.67. BOC Sciences 9
Darunavir [(3R,3aS,6aR)-2,3,3a,4,5,6a-Hexahydrofuro[5,4-b]furan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate. HIV-1-protease inhibitor. CAS No. 206361-99-1. Product ID: 2-08348. Molecular formula: C27H37N3O7S. Mole weight: 547.66. Reference: J. Med. Chem., 48, 1813, 2005. CarboMer Inc
Darunavir 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H37N3O7S. CAS No. 206361-99-1. Prepack ID 90027035-25mg. Molecular Weight 547.66. See USA prepack pricing. Molekula Americas
Darunavir Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC 50 = 0.003 μM; IC 90 = 0.009 μM) with minimal cytotoxicity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC114; UIC-94017. CAS No. 206361-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17040. MedChemExpress MCE
Darunavir ?98% (HPLC). Group: Fluorescence/luminescence spectroscopycovid-19 research and reference materialsenzyme activators, inhibitors & substrates. Alternative Names: Darunavir, Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester (9CI),Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, Prezista, TMC 114 (inhibitor), Carbamic acid, [3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, hexahydrofuro[2,3-b]furan-3-yl ester, [3R-[3?(1S*,2R*),3a?,6a?]]-, TMC 41629, UIC 94017, (-)-Darunavir, TMC 114. Alfa Chemistry Analytical Products
Darunavir ([ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenyl-methyl) propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester, TMC-114, UIC-94017) Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Alternative Names: [ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenyl-methyl) propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester; TMC-114; UIC-94017. Grades: Highly Purified. CAS No. 206361-99-1. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
Worldwide
Darunavir-d9 ([ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl-d9) amino]-2-hydroxy-1- (phenyl-methyl) propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester, TMC-114-d9, UIC-94017-d9) Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Group: Biochemicals. Alternative Names: [ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl-d9) amino]-2-hydroxy-1- (phenyl-methyl) propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester; TMC-114-d9; UIC-94017-d9. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Darunavir Ethanolate Darunavir Ethanolate is a nonpeptidic HIV protease inhibitor, used to treat HIV infection. Uses: Hiv protease inhibitors. Synonyms: Phosphonoformate. Grades: >98%. CAS No. 635728-49-3. Molecular formula: C27H37N3O7S·C2H5OH. Mole weight: 593.73. BOC Sciences 9
Darunavir Ethanolate Darunavir Ethanolate. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -3-[[ (4-aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenylmethyl) propyl]carbamic Acid (3R, 3aS, 6aR)Hexahydrofuro[2, 3-b]furan-3-yl Ester compd. with Ethanol. Grades: Highly Purified. CAS No. 635728-49-3. Pack Sizes: 5mg. Molecular Formula: C29H43N3O8S, Molecular Weight: 593.73. US Biological Life Sciences. USBiological 3
Worldwide
Darunavir Ethanolate Darunavir ethanolate (TMC114 Ethanolate) is a potent HIV protease inhibitor used to treat and prevent HIV/AIDS. Darunavir has a K i of 1 nM for wild type HIV-1 protease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC114 Ethanolate. CAS No. 635728-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17041. MedChemExpress MCE
Darunavir impurity 18 Darunavir impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1402142-62-4. Molecular formula: C20H29N3O3S. Mole weight: 391.53. Catalog: APB1402142624. Alfa Chemistry Analytical Products 4
Darunavir Impurity 2 Darunavir Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl ((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate. CAS No. 1526916-57-3. Molecular formula: C22H31N3O5S. Mole weight: 449.56. Catalog: APB1526916573. Alfa Chemistry Analytical Products 4
Darunavir impurity 3 Darunavir impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1402142-63-5. Molecular formula: C27H37N3O7S. Mole weight: 547.67. Catalog: APB1402142635. Alfa Chemistry Analytical Products 4
Darunavir Impurity A Darunavir Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide. CAS No. 169280-56-2. Molecular formula: C20H29N3O3S. Mole weight: 391.53. Catalog: APB169280562. Alfa Chemistry Analytical Products 4
Darunavir N-β-D-Glucuronide Darunavir N-β-D-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: 1-Deoxy-1-[[4-[[[ (2R, 3S) -3-[[[[ (3R, 3aS, 6aR) -hexahydrofuro[2, 3-b]furan-3-yl]oxy]carbonyl]amino]-2-hydroxy-4-phenylbutyl] (2-methylpropyl) amino]sulfonyl]phenyl]amino]-β -D-glucopyranuronic Acid. Grades: > 95%. CAS No. 1159613-25-8. Molecular formula: C33H45N3O13S. Mole weight: 723.79. BOC Sciences 8
Darunavir-O-Glucuronide Darunavir-O-Glucuronide is a metabolite of Darunavir, an inhibitor of human immunodeficiency virus protease. Synonyms: Darunavir O-β-D-Glucuronide. Grades: > 95%. CAS No. 1159613-27-0. Molecular formula: C33H45N3O13S. Mole weight: 723.79. BOC Sciences 8
Darusentan Darusentan (Lu-135252) is a selective endothelin receptor A ( ET-A ) receptor antagonist, which binds with a K i of 1.4 nM to the ET-A receptor and a K i of 184 nM to ET-B receptor, respectively with a 100-fold selectivity for ETA rather than ETB receptors [1]. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a K i of 13 nM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu-135252. CAS No. 171714-84-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15404. MedChemExpress MCE
Darusentan Darusentan is a selective endothelin-1 receptor A inhibitor. Darusentan is identified as the treatment of congestive heart failure, hypertension and cancers. It blocks endothelin ETA receptor thus results in an increase of sodium and potassium excretion in aging rats. Uses: Endothelin receptor antagonists. Synonyms: LU-135252; LU135252; LU 135252; HMR-4005; HMR 4005; HMR4005; (2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid. Grades: 95%. CAS No. 171714-84-4. Molecular formula: C22H22N2O6. Mole weight: 410.426. BOC Sciences 8
Darutoside Darutoside. Group: Biochemicals. Alternative Names: Darutin. Grades: Plant Grade. CAS No. 59219-65-7. Pack Sizes: 20mg. Molecular Formula: C26H44O8, Molecular Weight: 484.623. US Biological Life Sciences. USBiological 8
Worldwide
Darutoside Darutoside is a diterpenoid isolated from Siegesbeckia [1]. Uses: Scientific research. Group: Natural products. CAS No. 59219-65-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6028. MedChemExpress MCE
DASA-58 DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator. Synonyms: DASA-58; DASA 58; DASA58. Grades: 98%. CAS No. 1203494-49-8. Molecular formula: C19H23N3O6S2. Mole weight: 453.53. BOC Sciences 10
dasabuvir Dasabuvir is an antiviral drug for the treatment of hepatitis C. It inhibits hepatitis C virus (HCV) non-nucleoside NS5B palm polymerase to suppress RNA replicase. Dasabuvir is commonly used in combination with ombitasvir/paritaprevir/ritonavir to effect on HCV type 1. Uses: The treatment of hepatitis c. Synonyms: ABT333; ABT-333; ABT 333, Dasabuvir. Trade names: Viekira Pak (with ombitasvir/paritaprevir/ritonavir tablets), Exviera; N-(6-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide. Grades: 98.40%. CAS No. 1132935-63-7. Molecular formula: C26H27N3O5S. Mole weight: 493.578. BOC Sciences 8
Dasabuvir Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC 50 values of 7.7 and 1.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-333. CAS No. 1132935-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13998. MedChemExpress MCE
Dasatinib Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825. CAS No. 302962-49-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10181. MedChemExpress MCE
Dasatinib analog-1 Dasatinib analog-1 (compound 5826) inhibits CYP3A4 viability with a K i value of 5.4 μM. Dasatinib analog-1 blocks the formation of glutathione adducts [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1174416-41-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156883. MedChemExpress MCE
Dasatinib Carboxylic Acid Dasatinib Carboxylic Acid is an oxidative metabolite of Dasatinib (M6 metabolite), used in the treatment of cancers and immune diseases. Synonyms: 4-[6-[[5-[[(2-Chloro-6-methylphenyl)amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic Acid. Grades: > 95%. CAS No. 910297-53-9. Molecular formula: C22H24ClN7O3S. Mole weight: 501.99. BOC Sciences 8
Dasatinib Carboxylic Acid An oxidative metabolite of Dasatinib (M6 metabolite); used in the treatment of cancers and immune diseases. Group: Biochemicals. Alternative Names: 4-[6-[[5-[[ (2-Chloro-6-methylphenyl) amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic Acid. Grades: Highly Purified. CAS No. 910297-53-9. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Dasatinib Carboxylic Acid Ethyl Ester Protected Dasatinib Carboxylic Acid. An oxidative metabolite of Dasatinib (M6 metabolite); used in the treatment of cancers and immune diseases. Group: Biochemicals. Alternative Names: 4-[6-[[5-[[ (2-Chloro-6-methylphenyl) amino]carbonyl]-2-thiazolyl]amino]-2-methyl-4-pyrimidinyl]-1-piperazineacetic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 910297-62-0. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
Dasatinib-d8 A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic. Group: Biochemicals. Alternative Names: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl-d8]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide; BMS-354825-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
Dasatinib-d8 Dasatinib-d 8 is a deuterium labeled Dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BMS-354825-d8. CAS No. 1132093-70-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10181S. MedChemExpress MCE
Dasatinib-d8 N-Oxide The labeled oxidative metabolite of Dasatinib (M5 metabolite). Group: Biochemicals. Alternative Names: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl-d8]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide. Grades: Highly Purified. CAS No. 1189988-36-0. Pack Sizes: 500ug. US Biological Life Sciences. USBiological 2
Worldwide
Dasatinib Dimeric Impurity Dasatinib Dimeric Impurity. Group: Biochemicals. Alternative Names: 2, 2'-[1, 4-Piperazinediylbis[ (2-methyl-6, 4-pyrimidinediyl) imino]]bis[N- (2-chloro-6-methylphenyl) -5-thiazolecarboxamide. Grades: Highly Purified. CAS No. 910297-61-9. Pack Sizes: 1mg. Molecular Formula: C36H34Cl2N12O2S2, Molecular Weight: 801.77. US Biological Life Sciences. USBiological 3
Worldwide
Dasatinib Dimeric Impurity Dasatinib Dimeric Impurity is an impurity of Dasatinib (M24 metabolite), used in the treatment of cancers and immune diseases. Synonyms: 2,2'-((6,6'-(Piperazine-1,4-diyl)bis(2-methylpyrimidine-6,4-diyl))bis(azanediyl))bis(N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide). Grades: ≥95%. CAS No. 910297-61-9. Molecular formula: C36H34Cl2N12O2S2. Mole weight: 801.77. BOC Sciences 8
Dasatinib Free Base Dasatinib, also known as BMS-354825, is a cancer drug produced by Bristol-Myers Squibb and sold under the trade name Sprycel. Dasatinib is an oral dual BCR/ABL and Src family tyrosine kinases inhibitor approved for use in patients with chronic myelogenous leukemia (CML) after imatinib treatment and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It is also being assessed for use in metastatic melanoma. Group: Biochemicals. Alternative Names: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide; BMS-354825. Grades: Highly Purified. CAS No. 302962-49-8. Pack Sizes: 100mg, 500mg. Molecular Formula: C22H26ClN7O2S, Molecular Weight: 488.01. US Biological Life Sciences. USBiological 1
Worldwide
Dasatinib hydrochloride Dasatinib hydrochloride is a potent and dual Abl/ Src inhibitor. It inhibits c-Kit (WT)/c-Kit (D816V). Synonyms: BMS-354825 hydrochloride; BMS 354825 hydrochloride; BMS354825 hydrochloride;Sprycel hydrochloride. Grades: >98%. CAS No. 854001-07-3. Molecular formula: C22H27Cl2N7O2S. Mole weight: 524.47. BOC Sciences 10
Dasatinib hydrochloride Dasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib hydrochloride also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825 hydrochloride. CAS No. 854001-07-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10181A. MedChemExpress MCE
Dasatinib Impurity 2 Cas No. 302964-24-5. BOC Sciences 8
Dasatinib Impurity 5 Dasatinib Impurity 5 isan impurity of Dasatinib, a targeted therapy for chronic myeloid leukemia and certain types of acute lymphoblastic leukemia. Synonyms: 2-(4-(6-((5-((2-Chloro-6-methylphenyl)carbamoyl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethyl acetate. Grades: > 95%. CAS No. 1245157-85-0. Molecular formula: C24H28ClN7O3S. Mole weight: 530.04. BOC Sciences 8
Dasatinib monohydrate Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib monohydrate also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825 monohydrate. CAS No. 863127-77-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10181B. MedChemExpress MCE
Dasatinib Monohydrate N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazole carboxamide. Grades: USP. CAS No. 863127-77-9. Product ID: 8-04222. Molecular formula: C22H26ClN7O2S.H2O. Mole weight: 506.02. Purity: 0.99. CarboMer Inc

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