A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with K d value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACH-4471. CAS No. 1903768-17-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117930.
Daniquidone
Daniquidone, also known as Batracylin, is a water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits topoisomerases I and II, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. The acetylated form of daniquidone is highly toxic and is capable of inducing unscheduled DNA synthesis; rapid acetylators are more likely to experience toxicity with this agent. Synonyms: Batracylin; Bay H 2049; NSC-320846; 8-Aminoisoindolo[1,2-b]quinazolin-12(10H)-one. CAS No. 67199-66-0. Molecular formula: C15H11N3O. Mole weight: 249.27.
Danirixin
Danirixin is a small-molecule, selective, reversible, and non-peptide CXCR2 antagonist with high affinity (IC50 for CXCL8 binding = 12.5 nM). Synonyms: GSK1325756; GSK-1325756; GSK 1325756; Danirixin; N-(4-chloro-2-hydroxy-3-(3-piperidinylsulfonyl)phenyl)-N'-(3-fluoro-2-methylphenyl)urea. CAS No. 954126-98-8. Molecular formula: C19H21ClFN3O4S. Mole weight: 441.9.
Danofloxacin
Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase. Danofloxacinh has the potential for respiratory diseases in cattle, swine, and chickens treatment. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 112398-08-0. Molecular formula: C19H20FN3O3. Mole weight: 357.383. Product ID: ACM112398080. Alfa Chemistry ISO 9001:2015 Certified.
Danofloxacin
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C19H20FN3O3. CAS No. 112398-08-0. Prepack ID 51051393-100mg. Molecular Weight 357.38. See USA prepack pricing.
Danofloxacin
Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria , mycoplasma and chlamydia species , and plays an antimicrobial role by inhibition of bacterial DNA-gyrase. Danofloxacinh has the potential for respiratory diseases in cattle, swine, and chickens treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112398-08-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W011117.
Danofloxacin-[d3] is the labelled analogue of Danofloxacin. Danofloxacin is a fluoroquinolone synthetic antibacterial agent, which mainly acts by inhibiting bacterial DNA gyrase. Synonyms: Danofloxacin-D3; 1-Cyclopropyl-6-fluoro-7-(5-methyl-D3-2,5-diazabicyclo-[2.2.1]hept-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Danofloxacin D3 (methyl-D3); Danofloxacine-d3; Danofloxacino-d3; Advocin-d3; Advocip-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1217683-55-0. Molecular formula: C19H17D3FN3O3. Mole weight: 360.40.
Danofloxacin-d3 Mesylate
Labeled fluorinated quinolone antibacterial. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6-fluoro-1, 4-dihydro-7-[(1S, 4S)-5-(methyl-d3)-2, 5-diazabicyclo[2. 2. 1]hept-2-yl]-4-oxo-3-quinolinecarboxylic Acid Mesylate; Danofloxacin-d3 Methanesulfonate; CP-76136-27-d3; Advocin-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Danofloxacin mesylate
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C20H24FN3O6S. CAS No. 119478-55-6. Prepack ID 89967722-1g. Molecular Weight 453.49. See USA prepack pricing.
Danofloxacin mesylate
Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters ( P-gp and MRP2 ) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 76136-27. CAS No. 119478-55-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0501.
Danofloxacin mesylate
Danofloxacin mesylate. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6-fluoro-1, 4-dihydro-7-[(1S, 4S)-5-methyl-2, 5-diazabicyclo[2. 2. 1]hept-2-yl]-4-oxo-3-quinolinecarboxylic acid mesylate; Danofloxacin methanesulfonate; CP-76136-27. Grades: Highly Purified. CAS No. 119478-55-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C20H24FN3O6S. US Biological Life Sciences.
Worldwide
Danofloxacin Mesylate
Danofloxacin is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase. Uses: Anti-infective agents. Synonyms: CP-76136-27. Grade: >98%. CAS No. 119478-55-6. Molecular formula: C19H20FN3O3.CH4O3S. Mole weight: 453.48.
Fluorinated quinolone antibacterial. Group: Biochemicals. Alternative Names: Danofloxacin Methanesulfonate; CP-76136-27; Advocin. Grades: Highly Purified. CAS No. 119478-55-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Danofloxacin-(methyl-d3)
analytical standard. Group: Application areas.
Danoprevir
Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC 50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases ( IC 50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 ( IC 50 s=0.2-0.4 nM) as well as 2b and 3a ( IC 50 s=1.6, 3.5 nM) [1] [2]. Danoprevir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 0.05 μM [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITMN-191; R7227; RO5190591; RG7227. CAS No. 850876-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10238.
Danoprevir
Danoprevir(ITMN-191;R7227; RO5190591;RG7227) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Synonyms: RG7227; RG 7227; RG-7227; ITMN191; ITMN-191; ITMN 191; RO5190591; RO-5190591; RO 5190591. Grade: 0.98. CAS No. 850876-88-9. Molecular formula: C35H46FN5O9S. Mole weight: 731.837.
Danshen Root Extract (Standard). Applications: Role of coronary artery: treatment of coronary heart disease, can improve the coronary circulation, inhibit thrombosis disease. danshensu a significant expansion of coronary artery, increase coronary blood flow, reducing myocardial oxygen consumption, heart rate and increase the role of myocardial contractility; danshen capsule expansion animals comfortable arteriole, the capillary network and opening up in number and speed up the flow of blood , flow, thus improving microcirculation; anti-infective; for the treatment of cervical erosion. Group: Others. Synonyms: Danshen Root Extract (Standard). Purity: 3%, 5%, 10%, 20%, HPLC. Appearance: Brown-red powder. Storage: 24 months with original packing under 18°C. Store in cool dry place,avoid sunlight and high temperature. Source: Salvia miltiorrhiza Bge. Danshen Root Extract (Standard); plant extract. Pack: 1kg, 5kg, 10kg aluminum foil vacuum bag; or 20kg, 25kg Fiber Drum. Cat No: EXTW-205.
Danshensu
Danshensu, an active ingredient of Salvia miltiorrhiza, shows wide cardiovascular benefit by activating Nrf2 signaling pathway. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-2-Hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid. Product Category: Inhibitors. Appearance: Light beige solid. CAS No. 76822-21-4. Molecular formula: C9H10O5. Mole weight: 198.17. Purity: 0.98. IUPACName: (2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid. Canonical SMILES: C1=CC(=C(C=C1C[C@H](C(=O)O)O)O)O. Density: 1.546 g/ml. Product ID: ACM76822214. Alfa Chemistry ISO 9001:2015 Certified.
Danshensu
Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species ( ROS ) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC 50 of 0.97?μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Dan shen suan A; Salvianic acid A. CAS No. 76822-21-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N1913.
Danshensu sodium
Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species ( ROS ) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC 50 of 0.97?μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Dan shen suan A sodium; Salvianic acid A sodium. CAS No. 81075-52-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1913A.
Dansyl acid. Group: Biochemicals. Alternative Names: 5-Di methyl aminonaphthalene-1-sulfonic acid; 5-(Dimethylamino)-1-naphthalenesulfonic acid. Grades: Highly Purified. CAS No. 4272-77-9. Pack Sizes: 10g, 25g, 50g. Molecular Formula: C12H13NO3S. US Biological Life Sciences.
Worldwide
Dansyl Acid-d6
A fluorescent molecule used in protein analysis and FRET detection. Group: Biochemicals. Alternative Names: 5-Di methyl aminonaphthalene-1-sulfonic Acid-d6; 5-(Dimethylamino)-1-naphthalenesulfonic Acid-d6. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Dansyl-Ala-Arg-OH
Dansyl-Ala-Arg-OH is a fluorescent substrate of carboxypeptidase M, and its fluorescence intensity is the same as the cleavage product Dansyl-Ala-OH (λex = 340 nm; λem = 495 nm), the product has to be extracted with chloroform. The uncleaved substrate is still in the aqueous phase (acidic pH). Synonyms: N-dansyl-L-alanyl-L-arginine; N-{[5-(Dimethylamino)-1-naphthyl]sulfonyl}-L-alanyl-L-arginine; L-Arginine, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-alanyl-; (S)-2-((S)-2-(5-(dimethylamino)naphthalene-1-sulfonamido)propanamido)-5-guanidinopentanoic acid. Grade: 95%. CAS No. 87687-46-5. Molecular formula: C21H30N6O5S. Mole weight: 478.57.
Dansylamidoethyl mercaptan
Dansylamidoethyl mercaptan. Group: Biochemicals. Alternative Names: 2-(5-Dimethylaminonaphth-1-ylsulfonamido)ethyl mercaptan; 5- (Di methyl amino) -N- (2-mercaptoethyl) -1-naphthalene sulfonamide. Grades: Highly Purified. CAS No. 5354-61-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C14H18N2O2S2. US Biological Life Sciences.
Dansylaminoethyl-cyclen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2-(5-(DIMETHYLAMINO)-1-NAPTHALENESULFONAMIDO)ETHYL)-1,4,7,10-TETRAAZACYCLODODECANE, TETRAHYDROCHLORIDE, DIHYDRATE;DANSYLAMIDOETHYLCYCLEN;1-[2-(5-Dimethylamino-1-naphthalenesulfonamido)ethyl]-1,4,7,10-tetraazacyclododecane,tetrahydrochloride,dihydrate. Product Category: Heterocyclic Organic Compound. CAS No. 184537-03-9. Molecular formula: C22H36N6O2S.5ClH. Mole weight: 658.55. Purity: 0.96. IUPACName: 5-(diethylamino)-N-[2-(1,4,7,10-tetrazacyclododec-1-yl)ethyl]naphthalene-1-sulfonamide;dihydrate;tetrahydrochloride. Canonical SMILES: CCN(CC)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NCCN3CCNCCNCCNCC3.O.O.Cl.Cl.Cl.Cl. Product ID: ACM184537039. Alfa Chemistry ISO 9001:2015 Certified.
Dansyl-aniline
Dansyl-aniline is fluorescently labelled Aniline (A662475) which is used in the manufacture of dyes, medicinals, resins, varnishes, perfumes, as a vulcanizing rubber or even as a solvent. Group: Biochemicals. Grades: Highly Purified. CAS No. 34532-47-3. Pack Sizes: 25mg, 250mg. Molecular Formula: C18H18N2O2S. US Biological Life Sciences.
Worldwide
Dansylcadaverine
Dansylcadaverine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MDC,Monodansylcadaverine,N-(5-Amino-pentyl)-5-di-methyl-amino-phtha-lene-1-sulfon-amide,N-(Dimethyl-amino-phtha-lene-sulfonyl)-1,5-pentane-diamine. Product Category: Other Fluorophores. Appearance: Off-white solid. CAS No. 10121-91-2. Molecular formula: C17H25N3O2S. Mole weight: 335.46. Purity: 95%+. IUPACName: N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide. Canonical SMILES: CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NCCCCCN. Density: 1.190 ± 0.06 g/ml. Product ID: ACM10121912-1. Alfa Chemistry ISO 9001:2015 Certified.
Dansylcadaverine
Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands[1][2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Monodansyl cadaverine. CAS No. 10121-91-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-D1027.
Dansyl chloride
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DNSCl. CAS No. 605-65-2. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-D0017.
Dansyl chloride
25g Pack Size. Group: Stains & Indicators. Formula: C12H12ClNO2S. CAS No. 605-65-2. Prepack ID 22561258-25g. Molecular Weight 269.75. See USA prepack pricing.
Dansyl chloride
5g Pack Size. Group: Stains & Indicators. Formula: C12H12ClNO2S. CAS No. 605-65-2. Prepack ID 22561258-5g. Molecular Weight 269.75. See USA prepack pricing.
Dansyl chloride
Dansyl chloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Dimethylaminophthalene-1-sulfonyl chloride. Product Category: Other Fluorophores. CAS No. 605-65-2. Molecular formula: C12H12ClNO2S. Mole weight: 269.75. Product ID: ACM605652. Alfa Chemistry ISO 9001:2015 Certified.
Dansyl chloride
Dansyl chloride. Group: Biochemicals. Alternative Names: 5-Di methyl aminonaphthalene-1-sulphonyl chloride. Grades: Highly Purified. CAS No. 605-65-2. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C12H12ClNO2S. US Biological Life Sciences.
Worldwide
Dansyl chloride
BioReagent, suitable for fluorescence, ?99.0% (HPLC). Group: Reagents for amino acid analysis.
Dansyl Chloride - CAS 605-65-2
Reagent used for fluorescent labeling of proteins, N-terminal amino acids, and amines. Group: Fluorescence/luminescence spectroscopy.
Dansyl Chloride-d6
Labeled Dansyl Chloride. Reagent for fluorescent labelling of amines, amino acids and proteins. Group: Biochemicals. Alternative Names: 5-(Dimethylamino-d6)-1-naphthalenesulfonyl Chloride; 1-(Dimethylamino-d6)-5-naphthalenesulfonyl Chloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Dansyl-DL-aspartic acid bis(cyclohexylammonium) salt
Dansyl-DL-aspartic acid bis(cyclohexylammonium) salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[5-(Dimethylamino)naphthalene-1-sulfonyl]aspartic acid--cyclohexanamine (1/2). Appearance: White solid. CAS No. 102783-64-2. Molecular formula: C16H18N2O6S1. Mole weight: 564.74. Purity: 0.95. Product ID: ACM102783642. Alfa Chemistry ISO 9001:2015 Certified.
Dansyl-glu-gly-arg-chloromethylketone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: dansylglutamyl-glycyl-arginine chloromethyl ketone;Dansyl-Glu-Gly-Arg-chloromethylketone. Product Category: Heterocyclic Organic Compound. CAS No. 69024-84-6. Molecular formula: C26H36ClN7O7S. Mole weight: 626.131. Product ID: ACM69024846. Alfa Chemistry ISO 9001:2015 Certified.
Dansyl-Glu-Gly-Arg-chloromethylketone
Dansyl-Glu-Gly-Arg-chloromethylketone, an irreversible inhibitor of plasminogen activator, Factor Xa and urokinase, allows direct monitoring of labeled enzyme interactions. Uses: Fluorescent dyes. Synonyms: dansylglutamyl-glycyl-arginine chloromethyl ketone; Dns-EGR-CMK; 1,5-Dansyl-L-glutamylglycyl-L-arginine chloromethyl ketone; Dns-Glu-Gly-Arg chloromethyl ketone; Glycinamide, N-((5-(dimethylamino)-1-naphthalenyl)sulfonyl)-L-alpha-glutamyl-N-(4-((aminoiminomethyl)amino)-1-(chloroacetyl)butyl)-, (S)-. Grade: ≥95%. CAS No. 69024-84-6. Molecular formula: C26H36ClN7O7S. Mole weight: 626.13.
5-(Dimethylamino)naphthalene-1-sulfonohydrazide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 33008-06-9. Pack Sizes: 1 g; 5 g. Product ID: HY-W009411.
Dansyl-L-glutamine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DANSYL-L-GLUTAMINE;dansyl-L-glutamine free acid;N2-[[5-(dimethylamino)-1-naphthyl]sulphonyl]-L-glutamine;Dansyl-L-dlutamine;(2S)-2-(5-Dimethylamino-1-naphtylsulfonylamino)-4-carbamoylbutanoic acid;Dns-L-Gln-OH;N2-[[5-(Dimethylamino)-1-naphthalenyl]sulfon. Product Category: Heterocyclic Organic Compound. Appearance: Off-white Powder. CAS No. 1101-67-3. Molecular formula: C17H20N2O6S. Mole weight: 379.43. Product ID: ACM1101673. Alfa Chemistry ISO 9001:2015 Certified.
Dansyl-NECA
Dansyl-NECA. Group: Biochemicals. Grades: Purified. CAS No. 219982-12-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Dansyl-NECA
Dansyl-NECA is a selective fluorescent adenosine A1 receptor agonist and shows effects in permitting visualization of A1 receptors in the rat cerebellar cortex. Synonyms: Dansyl-NECA; DansylNECA; Dansyl NECA; 1-Deoxy-1-[6-[[6-[[[5-dimethylamino)-1-naphthalenyl]sulfonyl]amino]hexyl]amino]-9H-purin-9-yl]-N-ethyl-β-D-ribofuranuronamide. Grade: ≥99% by HPLC. CAS No. 219982-12-4. Molecular formula: C30H40N8O6S. Mole weight: 640.75.
Danthron
Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK. Uses: Scientific research. Group: Natural products. Alternative Names: Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone. CAS No. 117-10-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-B0923.
Dantocol DHE
100g Pack Size. Group: Building Blocks, Organics. Formula: C9H16N2O4. CAS No. 26850-24-8. Prepack ID 90023172-100g. Molecular Weight 216. See USA prepack pricing.
Dantrolene
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Dantrolene
Dantrolene. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DANTROLENE;DANTROLENE FREE BASE (FOR R&D ONLY). Product Category: Heterocyclic Organic Compound. CAS No. 85008-71-5. Molecular formula: C14H10N4O5. Mole weight: 314.25. Purity: 0.96. IUPACName: 1-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione. Canonical SMILES: C1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]. ECNumber: 230-684-8. Product ID: ACM85008715. Alfa Chemistry ISO 9001:2015 Certified.
Dantrolene
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. Synonyms: Dantrolenum [INN-Latin]; Dantroleno [INN-Spanish]; Dantrolenum; Ryanodex; 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin; Hydantoin, 1-((5-(p-nitrophenyl)furfurylidene)amino)-; 1-(((5-(4-Nitrophenyl)-2-furanyl)methylene)amino)-2,4-imidazolidinedione; 2,4-Imidazolidinedione, 1-(((5-(4-nitrophenyl)-2-furanyl)methylene)amino)-; 833480-90-3; 1-[[5-(p-Nitrophenyl)furfurylidene]amino]hydantoin; 1-(((5-(4-Nitrophenyl)furan-2-yl)methylene)amino)imidazolidine-2,4-dione; 1-[[[5-(4-Nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinedione; 2,4-Imidazolidinedione, 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-. Grade: 99% (HPLC). CAS No. 7261-97-4. Molecular formula: C14H10N4O5. Mole weight: 314.25.
Dantrolene
Dantrolene is an orally active, non-competitive glutathione reductase inhibitor with a K i of 111.6 μM and an IC 50 of 52.3 μM. Dantrolene is also a calcium channel protein inhibitor. Dantrolene inhibits the release of Ca 2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: F 368. CAS No. 7261-97-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12542.
Dantrolene-13C3
A labeled muscle relaxant (skeletal). Used in the treatment of malignant hyperthermia. Group: Biochemicals. Alternative Names: 1- [ [ [5- (4-Nitrophenyl) -2-furanyl] methylene] amino] -2, 4-imidazolidinedione-13C3; Dantrium-13C3. Grades: Highly Purified. CAS No. 1185234-99-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Dantrolene-[13C3]
Dantrolene-[13C3] is a labelled Dantrolene. Dantrolene is a muscle relaxant that acts via inhibiting Ca2+ ions release from sarcoplasmic reticulum. Dantrolene is used in the treatment of malignant hyperthermia. Synonyms: Dantrolene 13C3; 1-{[1-[5-(4-Nitrophenyl)-furan-2-yl]-methylidene]-amino}-imidazolidine-2,4-dione-[2,4,5-13C3]. Grade: 95% by HPLC; 98% atom 13C. CAS No. 1185234-99-4. Molecular formula: C11[13C]3H10N4O5. Mole weight: 317.28.
Dantrolene Impurity 2
5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone is an impurity in the synthesis of Dantrolene, a muscle relaxant (skeletal). Dantrolene is used in the treatment of malignant hyperthermia. Synonyms: 5-(4-Nitrophenyl)-2-furaldehyde-(2-carboxymethyl) Semicarbazone; [(Aminocarbonyl)[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazino]acetic Acid; Dantrolene Impurity. Grade: > 95%. CAS No. 57268-33-4. Molecular formula: C14H12N4O6. Mole weight: 332.27.
Dantrolene Impurity 3
2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester is an intermediate used in the synthesis of 1-(5-Phenylfurfurylideneamino)hydantoins. Synonyms: 2-[1-(Aminocarbonyl)-2-[[5-(4-nitrophenyl)-2-furanyl]methylene]hydrazinyl]-acetic Acid Ethyl Ester. Grade: > 95%. CAS No. 55227-60-6. Molecular formula: C16H16N4O6. Mole weight: 360.32.
Dantrolene Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Dantrolene Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Dantrolene Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Dantrolene sodium
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Dantrolene sodium
Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor with a K i of 111.6 μM and an IC 50 of 52.3 μM. Dantrolene sodium is also a calcium channel protein inhibitor. Dantrolene sodium inhibits the release of Ca 2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis (e.g., stroke, ischemia/reperfusion injury, and neurodegenerative diseases). Dantrolene sodium offers relief of muscle spasms, malignant hyperthermia, and antitoxic, antipyretic, and anti-inflammatory properties [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: F 440. CAS No. 14663-23-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-14657.
Dantrolene Sodium
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It suppresses the release of calcium previously sequestered by skeletal, but not cardiac, muscle sarcoplasmic reticulum. Synonyms: Dantrolene sodium salt; Dantrium; Sodium 3-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-2-oxo-4H-imidazol-5-olate. Grade: 98.0%~102.0%. CAS No. 14663-23-1. Molecular formula: C14H9N4NaO5. Mole weight: 336.239.
Dantrolene sodium hemiheptahydrate
Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by blocking excitation-contraction coupling in the muscle fiber. Uses: Muscle relaxants, central. Synonyms: Dantrolene sodium salt; Dantrium; Sodium dantrolene. Grade: ≥99%. CAS No. 24868-20-0. Molecular formula: C14H9N4O5·7/2H2O·Na. Mole weight: 399.29.