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An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. Group: Enzymes. Enzyme Commission Number: EC 3.6.5.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4716; dynamin GTPase; EC 3.6.5.5. Cat No: EXWM-4716.
A cell-permeable, allosteric Dynamin inhibitor (IC50=6.9uM and 14uM for full length Dynamin I and Dynamin II GTPase activity, respectively, in vitro). 10uM of this compound results in cytokinesis failure at the abscission stage in HeLa cultures, with 82% of cells that enter into mitosis becoming multinucleated, and with 97% resulting in cell death. However, it displays a much reduced effect in NIH3T3 cells at the same concentration. It elicits a dose-dependent reduction in cell growth against SMA-560, SJ-G2, SW480, MCF-7 and A2780 cultures, as being the most sensitive among a panel of other cancer cell lines (GI50=4.0 - 37uM). It was further shown to be 6-fold more active (IC50=5.0uM) than dynamin mediated receptor mediated endocytosis (RME) in U2OS cells, and 15-fold more active (IC50=1.3uM) than Dynasore in another Dynamin I GTPase activity assay. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Dynamin inhibitory peptide
Has been found to be a peptide inhibitor of the GTPase dynamin and competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Synonyms: Dynamin inhibitory peptide; 251634-21-6; L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl-; QVPSRPNRAP; HY-P1083; AKOS024456770; MS-31983; CS-0027626. Grade: >98%. CAS No. 251634-21-6. Molecular formula: C47H80N18O14. Mole weight: 1121.26.
Dynamin inhibitory peptide
Dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DYNAMIN INHIBITORY PEPTIDE;P4. Product Category: Inhibitors. Appearance: Solid. CAS No. 251634-21-6. Molecular formula: C61H107N19O14. Mole weight: 1121.25. Purity: 0.9617. Product ID: ACM251634216. Alfa Chemistry ISO 9001:2015 Certified.
Dynamin inhibitory peptide Acetate
Dynamin inhibitory peptide Acetate has been found to be a peptide inhibitor of the GTPase dynamin and competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Molecular formula: C49H84N18O16. Mole weight: 1181.30.
Dynamin inhibitory peptide, myristoylated
An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Synonyms: AKOS024456771; Dynamin inhibitory peptide,myristoylated; PD079118; S-251634-22-7. Grade: >99%. CAS No. 251634-22-7. Molecular formula: C61H107N19O14. Mole weight: 1330.64.
Dynamin inhibitory peptide, myristoylated acetate
An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Molecular formula: C63H111N19O16. Mole weight: 1390.67.
Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2222768-84-3. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-121802.
Dynarrestin
Dynarrestin is a potent and selective reversible inhibitor of dynein 1 and 2. Dynarrestin exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport. Synonyms: Ethyl 4-(4-(diethylamino)phenyl)-2-((2,4-difluorophenyl)amino)thiazole-5-carboxylate; 4-(4-Diethylaminophenyl)-2-(2,4-difluoro-phenylamino)-thiazole-5-carboxylic acid ethyl ester. Grade: ≥98% by HPLC. CAS No. 2222768-84-3. Molecular formula: C22H23F2N3O2S. Mole weight: 431.5.
Dynascone®
Dynascone®. CAS No. 56973-85-4. Kosher: Y. VIGON Item # 502771. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, galbascone.
America & Internationally
Dynascone® 10% DPG
Dynascone® 10% DPG. CAS No. MIXTURE. Kosher: Y. VIGON Item # 502772. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.
America & Internationally
Dynasore
Dynasore is a cell-permeable and noncompetitive inhibitor of the GTPase activity of dynamin with IC50 value of 15 μM. Synonyms: Dynamin Inhibitor I; 3-hydroxy-2-[(3,4-dihydroxyphenyl)methylene]hydrazide-2-naphthalenecarboxylic acid; N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide. Grade: 98%. CAS No. 304448-55-3. Molecular formula: C18H14N2O4. Mole weight: 322.31.
Dynasore
Dynamin GTPase inhibitor. Endocytosis inhibitor. Viral infection inhibitor. Destabilizes actin filaments. Inhibits entry of Trypanosoma into macrophages. Group: Biochemicals. Grades: Highly Purified. CAS No. 304448-55-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H14N2O4. 0.5H2O. US Biological Life Sciences.
Worldwide
Dynasore
Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 ?M. Dynasore blocks cell migration. Uses: Scientific research. Group: Signaling pathways. CAS No. 304448-55-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15304.
dynein ATPase
A multisubunit protein complex associated with microtubules. Hydrolysis of ATP provides energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome towards the microtubule's minus end. It also functions in the movement of eukaryotic flagella and cilia. It consists of two heavy chains (about 500 kDa), three-four intermediate chains (about 70 kDa) and four light chains (about 50 kDa). Group: Enzymes. Synonyms: dynein adenosine 5'-triphosphatase. Enzyme Commission Number: EC 3.6.4.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4704; dynein ATPase; EC 3.6.4.2; dynein adenosine 5'-triphosphatase. Cat No: EXWM-4704.
Dynemicin A
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1S,4R,4aR,14S,14aS)-1,4,4a,7,12,13,14,14a-Octahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-4a,14a-epoxy-4,14-(3-hexene-1,5-diyne-1,6-diyl)naphtho[2,3-c]phenanthridine-2-carboxylicacid; Dynemicin; BU 3420T. Grade: 95%. CAS No. 124412-57-3. Molecular formula: C30H19NO9. Mole weight: 537.47.
Dynemicin L
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylic acid, 8-chloro-5,8,9,14,15,16-hexahydro-1,4,6,17-tetrahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9R,14S,17S,18S)-(9CI). CAS No. 127032-74-0. Molecular formula: C30H22NO9Cl. Mole weight: 575.95.
Dynemicin M
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a-pentahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione. Grade: ≥98%. CAS No. 127003-54-7. Molecular formula: C29H23NO9. Mole weight: 529.49.
Dynemicin N
It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylicacid,5,8,9,14,15,16-hexahydro-1,4,6,8,17-pentahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9S,14S,17S,18S)-(9CI). CAS No. 127003-55-8. Molecular formula: C30H23NO10. Mole weight: 557.50.
Dynemicin O
It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a,17-hexahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; (8R-(8alpha,9beta,14beta,17S*,18R*))-8,9,14,15-Tetrahydro-1,4,6,8,10,17-hexahydroxy-20-methoxy-18-methyl-9,8,14-(1)butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione. CAS No. 138370-12-4. Molecular formula: C29H23NO10. Mole weight: 545.49.
Dynemicin P
It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-3β,4a,6,8,11,14a-hexahydroxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; 9,8,14-(1)Butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione,8,9,14,15-tetrahydro-1,4,6,8,17,20-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*,18R*))-. CAS No. 138370-13-5. Molecular formula: C28H21NO9. Mole weight: 515.47.
Dynemicin Q
It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: 9,8,14-(2)Buten(1)yl(4)ylideneanthra(1,2-b)benz(f)azocine-5,6,20-trione,8,9,14,15-tetrahydro-1,4,6,8,17,19-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*))-. CAS No. 138370-14-6. Molecular formula: C28H19NO9. Mole weight: 513.45.
Dyngo-4a
Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1?μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively. Synonyms: Hydroxy-Dynasore; 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide; 3-Hydroxy-N'-(2,4,5-trihydroxybenzylidene)-2-naphthohydrazide; Dyngo 49. Grade: ≥96%. CAS No. 1256493-34-1. Molecular formula: C18H14N2O5. Mole weight: 338.31.
Dynole 2?24
Dynole 2-24 is an active in-cell inhibitor of clathrin-mediated endocytosis (CME) and an indole-based dynamin GTPase inhibitor with an IC50 of 0.56 μM for dynamin I. It is non-toxic and shows enhanced potency against Dynamin I and II in vitro and in cells (IC50(CME) = 1.9 μM), and also shows 4.4-fold selectivity for dynamin I. Synonyms: 1H-Indole-3-methanamine, N-decyl-1-[3-(dimethylamino)propyl]-; N-({1-[3-(Dimethylamino)propyl]-1H-indol-3-yl}methyl)-1-decanamine. CAS No. 1416313-72-8. Molecular formula: C24H41N3. Mole weight: 371.60.
Dynole 34-2
Dynole 34-2 is a dynamin I inhibitor with IC50 value of 1.3 μM. It also inhibits receptor-mediated endocytosis (RME) with IC50 value of 5.0 μM. Synonyms: 2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide. Grade: ≥99% by HPLC. CAS No. 1128165-88-7. Molecular formula: C25H36N4O. Mole weight: 408.58.
Dynole 34-2
Dynole 34-2. Group: Biochemicals. Grades: Purified. CAS No. 1128165-88-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Dynole 34-2
Dynole 34-2 is a potent dynamin GTPase inhibitor (IC50s=6.9 and 14.2 μM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1128165-88-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107545.
Dynorphin (1-17)
Dynorphin A is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Uses: Neurotransmitter agents. Synonyms: Dynorphin A (swine); Dynorphin A (pig); 1-17-Dynorphin; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-; Dyn-A17; Dynorphin 17; Dynorphin A; Dynorphin A (1-17); Dynorphin A (human); Dynorphin A (porcine); Dynorphin A (rat); Dynorphin A 1-17; Dynorphin-A (Bos taurus); Porcine dynorphin (1-17); Porcine dynorphin A (1-17); Proteins, Dyn-A17; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln. Grade: ≥95%. CAS No. 80448-90-4. Molecular formula: C99H155N31O23. Mole weight: 2147.51.
Dynorphin A
Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 80448-90-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1333.
Dynorphin A 1-10
Dynorphin A 1-10 is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with IC50 of 42.0 μM. Synonyms: Dynorphin A, porcine, fragment 1-10; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline; Dynorphin A (1-10), porcine. Grade: ≥95%. CAS No. 79994-24-4. Molecular formula: C57H91N19O12. Mole weight: 1234.45.
Dynorphin A 1-10 acetate
Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with an IC50 of 42.0 μM. Synonyms: H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline acetic acid; 1-10-Dynorphin A (swine) acetate; α-Neoendorphin (pig), 7-L-arginine-8-L-isoleucine-9-L-arginine-10-L-proline-, acetate (1:1); Porcine dynorphin A (1-10) acetate. Grade: ≥95%. Molecular formula: C59H95N19O14. Mole weight: 1294.53.
Dynorphin A (1-10) TFA
Dynorphin A (1-10) TFA is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. Synonyms: Dynorphin A (1-10) Trifluoroacetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.TFA; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline Trifluoroacetate; Dynorphin A (1-10), porcine Trifluoroacetate. Grade: >98%. Molecular formula: C57H91N19O12.C2HF3O2. Mole weight: 1348.48.
Dynorphin A (1-13)
Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Dynorphin A Porcine Fragment 1-13; Porcine dynorphin A(1-13); H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysine; 1-13-Dynorphin A (swine). Grade: 98%. CAS No. 72957-38-1. Molecular formula: C75H126N24O15. Mole weight: 1603.95.
Dynorphin A (1-13) amide
Dynorphin A (1-13) amide is an antagonist of human MC1, MC3 and MC4 receptors. Synonyms: Dynorphin A (1-13), amide, porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide; Linear Dyn A-(1-13)NH2; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-(diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide. Grade: ≥95%. CAS No. 79515-34-7. Molecular formula: C75H127N25O14. Mole weight: 1602.97.
Dynorphin A (1-17) (Kappa Opioid Receptor Agonist)
An endogenous agonist for kappa opioid receptors. Involved in several neurological disorders, including neuropathic pain, stress, depression, and Alzheimer's and Parkinson's diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 80448-90-4. Pack Sizes: 500ug, 1mg, 5mg, 10mg. Molecular Formula: C99H155N31O23, Molecular Weight: 2147.5. US Biological Life Sciences.
Worldwide
Dynorphin A (1-8)
Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC 50 =303 nM) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 75790-53-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P2159.
Dynorphin A (1-8)
Dynorphin A (1-8) is an opioid octapeptide that exhibits agonist activity at μ and δ receptors. Synonyms: Dynorphin A fragment 1-8 porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH. Grade: 98%. CAS No. 75790-53-3. Molecular formula: C46H72N14O10. Mole weight: 981.15.
Dynorphin A (2-12), porcine
Dynorphin A is an endogenous opioid peptide that preferentially activates κ opioid receptors. Synonyms: Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu. Molecular formula: C60H105N21O12. Mole weight: 1312.69.
Dynorphin A acetate
Dynorphin A acetate is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Synonyms: Dynorphin (1-17) acetate; Dynorphin A (human, pig, rat, Bos taurus) acetate; Porcine dynorphin (1-17) acetate; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-, acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C101H159N31O25. Mole weight: 2207.58.
Dynorphin B 1-13
Dynorphin B is a 13-residue opioid peptide, which is derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an opioid peptide and a κ-opioid receptor agonists. It has been implicated in antinociceptive functions. It has also been used to prime cardiogenesis in pluripotent embryonic stem cells. Synonyms: Prodynorphin (226-238) (human); Prodynorphin (228-240) (porcine); Rimorphin; Dynorphin B 1-13; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-OH; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-phenylalanyl-L-lysyl-L-valyl-L-valyl-L-threonine. Grade: ≥95%. CAS No. 83335-41-5. Molecular formula: C74H115N21O17. Mole weight: 1570.84.
Dynorphin B (1-13) acetate
Dynorphin B (1-13) acetate acts as an opioid peptide and a κ-opioid receptor agonists. Molecular formula: C76H119N21O19. Mole weight: 1630.89.
Dynorphin B (1-9) trifluoroacetate salt
Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. Dynorphin B (1-9) is a competitive inhibitor of dynorphin A (1-9). Grade: ≥95%. Molecular formula: C54H78N16O12·xCF3COOH. Mole weight: 1143.30.
Dyphylline
Bronchodilator. Group: Biochemicals. Alternative Names: 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-purine-2,6-dione; Diprophylline. Grades: Highly Purified. CAS No. 479-18-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Dyphylline
Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor. Uses: Bronchodilator agents; phosphodiesterase inhibitors; vasodilator agents. Synonyms: Diprophylline. Grade: >98%. CAS No. 479-18-5. Molecular formula: C10H14N4O4. Mole weight: 254.24.
Dyrk1A-IN-1
Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity (IC50 = 119 nM) and the aggregation of tau and α-syn oligomers. Synonyms: Dyrk1A-IN-1; CS-0255852. Molecular formula: C23H20N4O3S. Mole weight: 432.49.
Dyrk1A-IN-4
Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC 50 s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2091883-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-147066.
DYRK1-IN-1
DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor. DYRK1-IN-1 inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. DYRK1-IN-1 can be used for the research of central nervous system penetrant DYRK1A chemical probe[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2814486-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132308.
DYRK1-IN-1
DYRK1-IN-1 is a highly selective and ligand efficient DYRK1A inhibitor that inhibits DYRK1A phosphorylation activity with an IC50 of 220 nM. It can be used to study the central nervous system penetrant DYRK1A chemical probe. Synonyms: N,N-dimethyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)-2-pyrimidinamine. Grade: ≥99%. Molecular formula: C12H12N6. Mole weight: 240.26.
DYRK2, active, GST tagged human
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy.
DYRKs-IN-1
DYRKs-IN-1 is a potent inhibitor of DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. It has antitumor activity. Synonyms: N-{5-[(3-Amino-1-phenylpropyl)carbamoyl]-2-chlorophenyl}-2-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-7-oxo-1,7-dihydropyrido[2,3-d]pyrimidine-6-carboxamide; Pyrido[2,3-d]pyrimidine-6-carboxamide, N-[5-[[(3-amino-1-phenylpropyl)amino]carbonyl]-2-chlorophenyl]-7,8-dihydro-2-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-7-oxo-. Grade: ≥95%. CAS No. 1387090-01-8. Molecular formula: C30H30ClN7O4. Mole weight: 588.06.
DYRKs-IN-1 hydrochloride
DYRKs-IN-1 hydrochloride is a potent inhibitor of DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. It has antitumor activity. Synonyms: N-(5-((3-amino-1-phenylpropyl)carbamoyl)-2-chlorophenyl)-2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide hydrochloride. Grade: ≥95%. CAS No. 1386980-55-7. Molecular formula: C30H31Cl2N7O4. Mole weight: 624.52.
DYRKs-IN-2
DYRKs-IN-2 is a potent inhibitor of DYRKs with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. It has antitumor activity. Synonyms: N-(5-(3-Amino-1-phenylpropylcarbamoyl)-2-chlorophenyl)-2-(3-(4-methylpiperazin-1-yl)propylamino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide; N-{5-[(3-Amino-1-phenylpropyl)carbamoyl]-2-chlorophenyl}-2-{[3-(4-methyl-1-piperazinyl)propyl]amino}-7-oxo-1,7-dihydropyrido[2,3-d]pyrimidine-6-carboxamide. Grade: ≥95%. CAS No. 1386980-04-6. Molecular formula: C32H38ClN9O3. Mole weight: 632.16.
Dysporium (III) oxide
Dysporium (III) oxide
Sarchem Laboratories New Jersey NJ
Dysprosium
Dysprosium. Uses: There are not many uses for dysprosium. scientists continue to experiment with it as apossible alloy metal (it has a high melting point) to be mixed with steel to make control rodsthat absorb neutrons in nuclear reactors. there are only a few commercial uses for dysprosium,such as a laser material and as a fluorescence activator for the phosphors used to produce thecolors in the older tv and computer cathode ray tubes (crts). when combined with steelor nickel as an alloy, it makes strong magnets. Additional or Alternative Names: Dysprosium, plasma standard solution, Specpure(R), Dy 10,000microg/ml; Dysprosium, powder, 5g, max. particle size 500 micron, 99.9%; TRA-0193167; Dysprosium rod, 6.35mm (0.25in) dia; Dysprosium foil, 3N; Dysprosium, foil, thickness 0.2 mm, size 25 x 75 mm, purity 99%; Dysprosium, wire reel, 100mm, diameter 1.0mm, hard, 99.9%; Dysprosium, foil, thickness 0.50 mm, size 50 x 50 mm, tolerance 0.2; Dysprosium, foil, 100x100mm, thickness 0.125mm, as rolled, 99%; Dysprosium pieces, distilled dendritic. Product Category: Nanoparticles & Nanopowders. CAS No. 7429-91-6. Molecular formula: Dy. Mole weight: 162.5g/mol. IUPACName: dysprosium. Canonical SMILES: [Dy]. ECNumber: 231-073-9. Product ID: ACM7429916. Alfa Chemistry ISO 9001:2015 Certified.
Dysprosium Acetate
Dysprosium Acetate. Grades: 99.9% Extremely High (>=99%). CAS No. 115280-55-4. Pack Sizes: Gram Quantities: 100 gm , 500 gm. Order Number: 1618.
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Dysprosium Arsenide
Dysprosium Arsenide is a crystalline solid used as a semiconductor and in photo optic applications. An arsenide, an anion with the charge -3, is a rare mineral group consisting of compounds of one or more metals with arsenic (As). Arsenide anions have no existence in solution since they are extremely basic. These solid salts have very hHigh lattice energies and are toxic due to the inherent toxicity of arsenic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DYSPROSIUM ANTIMONIDE;DYSPROSIUM ARSENIDE;Dysprosium arsenide (dyas);Einecs 234-473-1. Product Category: Heterocyclic Organic Compound. Appearance: Crystalline. CAS No. 12005-81-1. Molecular formula: DyAs. Mole weight: 237g/mol. Product ID: ACM12005811. Alfa Chemistry ISO 9001:2015 Certified.
Dysprosium Bromide
Dysprosium Bromide. Grades: 99.9% Extremely High (>=99%). CAS No. 14456-48-5. Pack Sizes: Gram Quantities: 100 gm , 500 gm. Order Number: 1633.
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Dysprosium Carbonate
Dysprosium Carbonate. Grades: 99.99% Extremely High (>=99%). CAS No. 38245-35-1. Pack Sizes: Gram Quantities: 25 gm , 100 gm. Order Number: 1636.
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Dysprosium chips
Dysprosium chips. Grades: 99.9% Extremely High (>=99%). CAS No. 7429-91-6. Pack Sizes: Gram Quantities: 10 gm, 50gm. Order Number: 1612.
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Dysprosium Chloride
Dysprosium Chloride. Grades: 99.99% Extremely High (>=99%). CAS No. 15059-52-6. Pack Sizes: Kilogram Quanitites: 1 kg, 5 kg. Order Number: 1640.
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Dysprosium Chloride
Dysprosium Chloride. Grades: 99.9% Extremely High (>=99%). CAS No. 15059-52-6. Pack Sizes: Gram Quantities: 25 gm , 100 gm. Order Number: 1639.
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Dysprosium Chloride, anhydrous
Dysprosium Chloride, anhydrous. Grades: 99.9% Extremely High (>=99%). CAS No. 10025-74-8. Pack Sizes: Gram Quantities: 10 gm, 100 gm. Order Number: 1642.
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Dysprosium (Dy)
Dysprosium (Dy). Group: Magnetic nanoparticles. Alternative Names: High Purity Dysprosium (Dy); 99.9% Dysprosium (Dy); 99.99% Dysprosium (Dy); 99.999% Dysprosium (Dy). 3N-5N.
Dysprosium (Dy) Evaporation Material
Dysprosium (Dy) Evaporation Material. Group: other nano materials. Alternative Names: Dy Pellets, Dy Pieces, Dysprosium Pellets, Dysprosium Pieces, Dysprosium Evaporation Material, Dy Evaporation Material, Dy Evapor Materials, Dysprosium Evapor Materials. 99.99%.
Dysprosium (Dy) Sputtering Targets
Dysprosium (Dy) Sputtering Targets. Group: Sputtering targets. Alternative Names: Dysprosium (Dy) Sputtering Targets, Dy Sputtering Target, Dy Sputter Target, Dy Target, Dysprosium Sputtering Target, Dysprosium Sputter Target, Dysprosium Target. 99.99%.