A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Duocarmycin MB is an antibody drug conjugate (ADC) toxin that can be used against multidrug resistant cell lines. Duocarmycin is a DNA alkylating agent that binds in minor groove. Synonyms: Carbamic acid, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]carbamate; 2-Methyl-2-propanyl (2-{[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl]carbonyl}-1H-indol-6-yl)carbamate. Grade: ≥95%. CAS No. 1613286-58-0. Molecular formula: C27H26ClN3O4. Mole weight: 491.97.
Duocarmycin SA
Duocarmycin SA is an orally active antitumor antibiotic with an IC50 of 10 pM[1]. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130288-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12456.
duolite c-26 ion-exchange resin. Group: Polymers. CAS No. 68441-33-8.
Duoxitasai Liposome
Duoxitasai is a paclitaxel derivative with 2 times the affinity and 10 times the activity of paclitaxel, with broad-spectrum antitumor effects. This product is a PEGylated pre-formulated liposome with duoxitasai. It is only for research purposes. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
DuP 105
DuP 105, an orally active oxazolidinone, is a new synthetic antimicrobial agent with activity against gram-positive bacteria. Synonyms: Dup-105; DuP105; 4-Methylsulfinylphenyloxooxazolidinylmethylacetamide; Acetamide, N-((3-(4-(methylsulfinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-; (S)-N-[3-(4-Methanesulfinyl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide. Grade: ≥95%. CAS No. 96800-41-8. Molecular formula: C13H16N2O4S. Mole weight: 296.34.
DuP 697
DuP 697. Group: Biochemicals. Grades: Purified. CAS No. 88149-94-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DuP-697
DuP-697 is a selective COX-2 inhibitor. Synonyms: DuP-697; DuP 697; DuP697; S-6907; S 6907; S6907; BFMT; 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene. CAS No. 88149-94-4. Molecular formula: C17H12BrFO2S2. Mole weight: 411.3.
Dup-721
Dup-721 is a new antimicrobial agent belonging to the oxazolidinone series, a new class of synthetic antibacterial agents. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dup-721; Dup721; Dup 721. Product Category: Others. Appearance: Solid powder. CAS No. 104421-21-8. Molecular formula: C14H16N2O4. Mole weight: 276.29. Purity: >98%. IUPACName: (S)-N-((3-(4-acetylphenyl)-2-oxooxazolidin-5-yl)methyl)acetamide. Canonical SMILES: CC(C1=CC=C(N2C[C@H](CNC(C)=O)OC2=O)C=C1)=O. Product ID: ACM104421218. Alfa Chemistry ISO 9001:2015 Certified.
DUPA
DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in agent conjugate to selectively deliver cytotoxic agents to prostate cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 302941-52-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111606.
DUPA-FITC
A PSMA targeting reagent with a FITC probe. Uses: For industrial and laboratory use. Product Category: Other Fluorescent Dyes. Molecular formula: C51H57N7O15S. Mole weight: 1040.1 g/mol. Purity: 0.9. Product ID: DYE-FLU-0104. Alfa Chemistry ISO 9001:2015 Certified.
DUPA(OtBu)-OH
DUPA(OtBu)-OH is a PEG linker for antibody-drug-conjugation (ADC). DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. Synonyms: (S)-5-tert-Butoxy-4-(3-((s)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic Acid; L-Glutamic acid, N-[[[(1S)-3-carboxy-1-[(1,1-dimethylethoxy)carbonyl]propyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester; 2-[3-(1,3-bis-tert-butoxycarbonylpropyl)ureido]pentanedioic acid 1-tert-butyl ester. Grade: 95%. CAS No. 1026987-94-9. Molecular formula: C23H40N2O9. Mole weight: 488.57.
dUpCp
dUpCp, a nucleoside analogue hailed for its therapeutic potential in treating viral infections such as hepatitis C and HIV, has garnered attention for its capacity to inhibit viral replication and to stymie further infection. What's more, this potent analogous substance holds great promise in fighting cancer, with studies demonstrating its propensity to selectively trigger apoptosis in cancer cells. Although the ramifications of its usage as an antitumor agent call for further inquiry into its efficacy, it's an exciting prospect indeed. Synonyms: dUMPCP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C10H16N2O10P2(free acid). Mole weight: 386.19 (free acid).
dUpCpp
dUpCpp - a chemical compound utilized in the field of biomedical research - holds promising potential as an enzyme activator which facilitates DNA and RNA replication. By augmenting the function of polymerases essential for viral replication, this unique substance presents a promising target for antiviral drug development. Furthermore, dUpCpp has been utilized to probe and unravel the mechanisms underlying the polymerization of DNA and RNA in a spectrum of systems. Synonyms: dUMPCPP; 2'-Deoxyuridine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 170428-84-9. Molecular formula: C10H17N2O13P3.xNa. Mole weight: 466.17 (free acid).
Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN-668; SAR-231893. CAS No. 1190264-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9926.
Dupilumab
Dupilumab, marketed under the brand name Dupixent, is a monoclonal antibody used to treat several chronic inflammatory conditions. It works by inhibiting the signaling of interleukin-4 (IL-4) and interleukin-13 (IL-13), which are cytokines involved in the inflammatory response. Dupilumab is approved for the treatment of several conditions, including, atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and eosinophilic esophagitis. Synonyms: Immunoglobulin, anti-(human interleukin 4 receptor α) (human REGN668 heavy chain), disulfide with human REGN668 κ-chain, dimer; Dupixent; REGN 668; SAR 231893. CAS No. 1190264-60-8.
Duplex 2209, 20 mesh woven from 0.3mm (0.012mm) dia wire
Duplex 2209, 20 mesh woven from 0.3mm (0.012mm) dia wire. Group: Alloys.
Duplex 2209, 40 mesh woven from 0.2mm (0.008mm) dia wire
Duplex 2209, 40 mesh woven from 0.2mm (0.008mm) dia wire. Group: Alloys.
Duplex 2209, 60 mesh woven from 0.15mm (0.006mm) dia wire
Duplex 2209, 60 mesh woven from 0.15mm (0.006mm) dia wire. Group: Alloys.
dUpNHp
dUpNHp, a noteworthy biochemical research instrument, exhibits extensive applicability in the modification and examination of enzymatic activity within cells. Remarkably, its specificity in targeting and altering the activity of protein kinases and G proteins has proven invaluable within the realm of biomedicine, aiding in the study of prevalent diseases such as diabetes, cancer, and Alzheimer's whilst facilitating the development of new drugs targeted to combat them. Synonyms: dUMPNP; 2'-Deoxyuridine-5'-[(α,β)-imido]diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 178809-71-7. Molecular formula: C9H15N3O10P2.xNa. Mole weight: 387.17 (free acid).
dUpNHpp
dUpNHpp, a formidable small molecule inhibitor with potential therapeutic benefits, is a contender in the battle against cancer. Its mode of action rests on disrupting protein-protein interactions, resulting in the arrest of tumor growth. Ovarian and breast cancer, both notorious for their lethality, have been subject to clinical trials with auspicious outcomes. Synonyms: dUMPNPP; 2'-Deoxyuridine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 170428-86-1. Molecular formula: C9H16N3O13P3.xNa. Mole weight: 467.15 (free acid).
Duramycin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ancovenin,2-L-lysine-6-(3-aminoalanine)-10-L-phenylalanine-12-L-phenylalanine-13-L-valine-15-(erythro-3-hydroxy-L-aspartic acid)-,cyclic 6-19)-imine; LANCOVUTIDE; Leucopeptin; UNII-BPR0F3X56H; Lancovutide [INN]. CAS No. 1391-36-2. Molecular formula: C89H125N23O25S3. Mole weight: 2013.28. Purity: 90+%. IUPACName: Duramycin. Canonical SMILES: CC1C2C(=O)NC(C(=O)NC(C(=O)NC3CSCC4C(=O)NC(CS1)C(=O)NC(CNCCCCC(NC(=O)C(CSCC(C(=O)NC(C(=O)NC(C(=O)N4)CCC(=O)N)CCCCN)N)NC(=O)C(NC(=O)CNC(=O)C(NC3=O)C(C(=O)O)O)CC(=O)N)C(=O)O)C(=O)NC(C(=O)NCC(=O)N5CCCC5C(=O)NC(C(=O)N2)CC6=CC=CC=C6)CC7=CC=CC=C7)C(C)C)CC8=CC=CC=C8. Product ID: ACM1391362. Alfa Chemistry ISO 9001:2015 Certified. Categories: Doramectin.
Duramycin
It is produced by the strain of Streptomyces cinnamomeus. It has activity against gram-positive bacteria, gram-negative bacteria (individual, weak), Mycobacterium and Candida albicans. Synonyms: 27,46-(Methaniminopentaniminomethano)-6,43:15,40-bis(methanothiomethano)pyrrolo[2,1-d1][1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52]thiaheptadecaazacyclopentapentacontine, cyclic peptide deriv.; Antibiotic PA 48009; Lancovutide; Leucopeptin; Ancovenin, 2-L-lysine-6-(3-aminoalanine)-10-L-phenylalanine-12-L-phenylalanine-13-L-valine-15-(erythro-3-hydroxy-L-aspartic acid)-, cyclic 6-19)-imine; Duramycin A. Grade: ≥90%. CAS No. 1391-36-2. Molecular formula: C88H123N23O25S3. Mole weight: 1999.25.
Duramycin
Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Moli1901; Lancovutide. CAS No. 1391-36-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106302.
Duramycin B
Duramycins B is a new lanthionine containing antibiotic, has been isolated from Streptoverticillium strain R2075. Duramycins B is a potent inhibitor of human phospholipase A2. It exhibits only a weak antibacterial activity against B.subtilis, and does not display antimicrobial activity against S.aureus, S.mitis, E.coli, K.pneumoniae, P.vulgaris and C.albicans. Grade: ≥98%. CAS No. 132246-31-2. Molecular formula: C86H127N25O25S3. Mole weight: 2007.27.
Duramycin C
Duramycin C is a new lanthionine containing antibiotic, has been isolated from Streptomyces griseoluteus (R2107). Duramycin C is a potent inhibitor of human phospholipase A2. It exhibits only a weak antibacterial activity against B.subtilis, and does not display antimicrobial activity against S.aureus, S.mitis, E.coli, K.pneumoniae, P.vulgaris and C.albicans. Grade: ≥98%. CAS No. 132268-38-3. Molecular formula: C82H115N23O27S3. Mole weight: 1951.12.
Durlobactam
Durlobactam is a novel β-lactamase inhibitor. It is designed to combat antibiotic resistance by inhibiting β-lactamase enzymes produced by certain bacteria, which can degrade β-lactam antibiotics. By inhibiting these enzymes, durlobactam allows β-lactam antibiotics to remain effective against resistant bacterial strains. Durlobactam is often combined with other antibiotics to enhance their efficacy, particularly in treating infections caused by multidrug-resistant organisms. Synonyms: Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl] ester; ETX 2514; ETX2514; ETX-2514; (1R,2S,5R)-2-(Aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate; (1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate. Grade: ≥95%. CAS No. 1467829-71-5. Molecular formula: C8H11N3O6S. Mole weight: 277.25.
Durlobactam sodium
Durlobactam, also known as ETX2514, is a beta-lactamase inhibitor drug candidate. Durlobactam sodium can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Synonyms: ETX 2514 sodium; ETX-2514 sodium; ETX2514 sodium; (1R,2S,5R)-2-Carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl sodium sulfate; Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl] ester, sodium salt (1:1); Durlobactam sodium salt; ETX 2514 Sodium salt. Grade: ≥95%. CAS No. 1467157-21-6. Molecular formula: C8H10N3NaO6S. Mole weight: 299.24.
Durlobactam sodium
Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC 50 s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETX2514. CAS No. 1467157-21-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117974.
Durlobactam triethylamine
Durlobactam triethylamine is a combination of durlobactam, a β-lactamase inhibitor, with triethylamine, an organic compound used to form a stable salt. Durlobactam enhances the effectiveness of β-lactam antibiotics by inhibiting the β-lactamase enzymes produced by certain bacteria, which would otherwise degrade the antibiotic and render it ineffective. This combination is used in the treatment of bacterial infections, particularly those caused by multidrug-resistant organisms. Synonyms: ETX 2514 Triethylamine; ETX-2514 Triethylamine; ETX2514 Triethylamine; Sulfuric acid, mono[(1R,2S,5R)-2-(aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl] ester, compd. with N,N-diethylethanamine (1:1); (1R,2S,5R)-2-(Aminocarbonyl)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate triethylamine; (1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl hydrogen sulfate triethylamine; Durlobactam TEA salt. Grade: ≥95%. CAS No. 3006792-47-5. Molecular formula: C14H26N4O6S. Mole weight: 378.45.
Duroquinone
Standard for quantitative NMR. Group: Volatile & semivolatile standards.
durvalumab
Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody. It was approved by FDA for the treatment of patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy, or whose disease has progressed within 12 months of receiving platinum-containing chemotherapy before or after surgery. Uses: The treatment of locally advanced or metastatic urothelial carcinoma. Synonyms: Imfinzi. CAS No. 1428935-60-7. Molecular formula: C6502H10018N1742O2024S42. Mole weight: 146.3.
Durvalumab
Durvalumab (MEDI 4736) is an human anti- PD-L1 monoclonal antibody [1]. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80 , with IC 50 s of 0.1 and 0.04 nM, respectively [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI 4736. CAS No. 1428935-60-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9919.
Durvalumab (anti-PD-L1)
Durvalumab (anti-PD-L1)(MEDI 4736) is a human anti- PD-L1 protein monoclonal antibody. Durvalumab (anti-PD-L1) completely blocks PD-L1 binding to PD-1 and CD80 , IC 50 are 0.1 and 0.04 nM respectively, has anti-tumor activity [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI 4736 (anti-PD-L1). CAS No. 1428935-60-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9919A.
Dusquetide
Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection [1]. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns. Uses: Scientific research. Group: Peptides. Alternative Names: SGX942. CAS No. 931395-42-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2076.
Dusquetide aceate
Dusquetide aceate modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide aceate shows activity in both reducing inflammation and increasing clearance of bacterial infection. Molecular formula: C27H51N9O7. Mole weight: 613.75.
Dusquetide TFA
Dusquetide TFA modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide TFA shows activity in both reducing inflammation and increasing clearance of bacterial infection. Synonyms: SGX942 TFA. Molecular formula: C27H48F3N9O7. Mole weight: 667.72.
Dustanin
Dustanin is a hopane isolated from Aschersonia. Synonyms: 15alpha,22-dihydroxyhopane; Hopane-15α,22-diol. CAS No. 3607-96-3. Molecular formula: C30H52O2. Mole weight: 444.73.
Dutacatib
Dutacatib. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dutacatib;N-[[2-Cyano-4-(2,2-dimethylpropylamino)pyrimidin-5-yl]methyl]-4-(4-methylpiperazin-1-yl)benzamide;Unii-L3m76J6S37. Product Category: Heterocyclic Organic Compound. CAS No. 501000-36-8. Molecular formula: C23H31N7O. Mole weight: 421.54. Density: 1.21. Product ID: ACM501000368. Alfa Chemistry ISO 9001:2015 Certified.
Dutasteride
Dutasteride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Avodart; Dutasteride; Duagen. Product Category: Steroidal Compounds. Appearance: White Crystalline Solid. CAS No. 164656-23-9. Molecular formula: C27H30F6N2O2. Mole weight: 528.53. Purity: 0.98. IUPACName: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Canonical SMILES: CC12CCC3C(C1CCC2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CCC5C3(C=CC(=O)N5)C. Density: 1.303 g/cm³. Product ID: ACM164656239. Alfa Chemistry ISO 9001:2015 Certified.
Dutasteride
Dutasteride. Group: Biochemicals. Alternative Names: (5a, 17b) -N-[2, 5-Bis (trifluoromethyl) phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide. Grades: Highly Purified. CAS No. 164656-23-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C27H30F6N2O2. US Biological Life Sciences.
Worldwide
Dutasteride
Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GG 745; GI 198745. CAS No. 164656-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13613.
Dutasteride
Dutasteride is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Synonyms: 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; 4-Azaandrost-1-ene-17-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-, (5α,17β)-; (5α,17β)-N-[(2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide; Avodart; Avolve; GG 745; GI 198745; Veltride. Grade: >98%. CAS No. 164656-23-9. Molecular formula: C27H30F6N2O2. Mole weight: 528.53.
Dutasteride
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H30F6N2O2. CAS No. 164656-23-9. Prepack ID 11556431-25mg. Molecular Weight 528.53. See USA prepack pricing.
Labeled Dutasteride. Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride. Dutasteride is used in the treatment of benign prostatic hyperplasia. Group: Biochemicals. Alternative Names: (4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N-[2, 5-Bis (trifluoromethyl) phenyl]-2, 4a, 4b, 5, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11, 11a-tetradecahydro-4a, 6a-dimethyl-2-oxo-1H-indeno[5, 4-f]quinoline-7-carboxamide-13C6; (5α,17 β)-. Grades: Highly Purified. CAS No. 1217685-27-2. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Dutasteride-[13C6]
Dutasteride-[13C6] is the labelled analogue of Dutasteride. Dutasteride is a triple 5α-reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone. Dutasteride is a medication primarily used to treat the symptoms of an enlarged prostate. Synonyms: Dutasteride 13C6. Grade: 95% by HPLC; 95% atom 13C. CAS No. 1217685-27-2. Molecular formula: C21[13C]6H30F6N2O2. Mole weight: 534.49.
Dutasteride Alpha-Dimer (~90%)
Dutasteride Alpha-Dimer (~90%). Uses: For analytical and research use. Group: Impurity standards. Catalog: APS001607. Format: Neat.
Dutasteride Beta-Dimer
Dutasteride Beta-Dimer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-[2,5-Bis(trifluoromethyl))phenyl]-3-oxo-4-[3-oxo-4-aza-5?-androst-1-ene-17?-carbonyl]-4-aza-5?-androst-1-ene-17?-carboxamide,1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1-[[(4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinolin-7-yl]carbonyl]-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-, Dutasteride Imp. I (EP), Dutasteride Dimer 1, Dutasteride ?-Dimer. CAS No. 1648593-70-7. IUPAC Name: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-6-[(1S,3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carbonyl]-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-1-carboxamide. Molecular formula: C46H55F6N3O4. Mole weight: 827.94. Catalog: APS1648593707. SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@H]4N(C(=O)[C@H]5CC[C@H]6[C@@H]7CC[C@H]8NC(=O)C=C[C@]8(C)[C@H]7CC[C@]56C)C(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2C(=O)Nc9cc(ccc9C(F)(F)F)C(F)(F)F. Format: Neat.
Dutasteride EP Impurity A
Dutasteride EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylic acid. CAS No. 104239-97-6. Molecular formula: C19H27NO3. Mole weight: 317.42. Catalog: APB104239976.
Dutasteride EP Impurity B
An impurity of Dutasteride, which is a potent dual inhibitor of 5α-reductase isoenzymes type 1 and type 2. Synonyms: N,N-Dimethyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide; Dutasteride Dimethyl amide Imp; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N,N,4a,6a-Tetramethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide; Dutasteride Impurity B. Grade: ≥95%. Molecular formula: C21H32N2O2. Mole weight: 344.49.
Dutasteride EP Impurity E
An impurity of Dutasteride, which is a potent dual inhibitor of 5α-reductase isoenzymes type 1 and type 2. Synonyms: Dutasteride Impurity E; 17a-Dutasteride; 17alpha-Dutasteride; (4aR,4bS,6aS,7R,9aS,9bS,11aR)-N-(2,5-Bis(trifluoromethyl)phenyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide; N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5αandrost-1-ene-17α-carboxamide; Dutasteride 17-alfa-epimer; Dutasteride 17α-Epimer; 17α-Dutasteride. Grade: ≥95%. CAS No. 2102935-76-0. Molecular formula: C27H30F6N2O2. Mole weight: 528.53.
Dutasteride (GG-745, GI-198745)
Used in the treatment of benign prostatic hyperlasia. It inhibits both isozymes of 5a-reductase. Group: Biochemicals. Alternative Names: GG-745, GI-198745. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Dutasteride Impurity F (1-Chloro Dihydro Dutasteride)
1-Chloro Dihydro Dutasteride is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride. Synonyms: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-4-chlorohexadecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 1365545-42-1. Molecular formula: C27H31ClF6N2O2. Mole weight: 564.99.
Dutasteride Impurity G (5,6-Dehydro-17β-dutasteride)
5,6-Dehydro-dutasteride is an impurity in the synthesis of Dutasteride. Synonyms: (4aR,4bS,6aS,7S,9aS,9bS)-N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10-dodecahydro-4a,6a-dimethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 1430804-85-5. Molecular formula: C27H28F6N2O2. Mole weight: 526.53.
Dutasteride Impurity J
An intermediate in the synthesis of Dutasteride and Dutasteride Impurity. Synonyms: [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα)]-N-[2,5-Bis(trifluoromethyl)phenyl]-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; (4aR,4bS,6aS,7S,9aS,9bS)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,3,4,4a,4b,5,6,6a. Grade: > 95%. CAS No. 164656-21-7. Molecular formula: C27H30F6N2O2. Mole weight: 528.54.
Dutasteride Impurity L
Dutasteride Impurity L is an impurity of Dutasteride, a medication used to treat benign prostatic hyperplasia (BPH) in men. Synonyms: DTXSID501100113; 1365545-48-7; (4bS,6aS,7S,9aS,9bS)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4b,5,6,6a,7,8,9,9a,9b,10,11-dodecahydro-6a-methyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 1365545-48-7. Molecular formula: C26H26F6N2O2. Mole weight: 512.5.
Dutasteride Related Impurity 1
Dutasteride Related Impurity. Synonyms: (5α,17β)-3-Oxo-4-azaandrost-1-ene-17-carboxamide; [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-Tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide. Grade: > 95%. CAS No. 104214-61-1. Molecular formula: C19H28N2O2. Mole weight: 316.44.
Dutogliptin
Dutogliptin is a selective and orally active DPP4 inhibitor. It can improve glycaemic control in patients with type 2 diabetes. But phase III clinical trials for the treatment of type 2 diabetes were discontinued. Uses: Type 2 diabetes mellitus. Synonyms: PHX 1149; PHX1149; PHX-1149; (2R)-1-(((3R)-Pyrrolidin-3-ylamino)acetyl)pyrrolidin-2-yl)boronic acid; 890402-81-0 (tartrate salt). Grade: 98%. CAS No. 852329-66-9. Molecular formula: C10H20BN3O3. Mole weight: 241.10.
Dutogliptin
Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 ( DPP4 ) inhibitor for the treatment of type 2 diabetes mellitus. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PHX-1149 free base. CAS No. 852329-66-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10286.
Dutomycin
It is produced by the strain of Streptomyces sp. 1725. Dutomycin has stronger cytotoxicity. 1 μg/mL of Dutomycin can completely inhibit P388 leukemia cells. Synonyms: 1,4,6,7(6aH,10H)-Naphthacenetetrone, 8-acetyl-10-((5-((2,6-dideoxy-4-O-(2,4-dimethyl-1-oxo-2-heptenyl)-3-C-methyl-alpha-L-xylo-hexopyranosyl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-10a,11-dihydro-5,6a,9,10a-tetrahydroxy-2-methoxy-12-methyl-, (2S-(2alpha(6aR*,10S*,10aS*),5beta(2Z,4S*),6alpha))-. CAS No. 146663-67-4. Molecular formula: C44H54O17. Mole weight: 854.89.
dUTP diphosphatase
This enzyme has a dual function: on one hand, it removes dUTP from the deoxynucleotide pool, which reduces the probability of this base being incorporated into DNA by DNA polymerases, while on the other hand, it produces the dTTP precursor dUMP. Lack or inhibition of dUTPase action leads to harmful perturbations in the nucleotide pool resulting in increased uracil content of DNA that activates a hyperactive futile cycle of DNA repair. Group: Enzymes. Synonyms: deoxyuridine-triphosphatase; dUTPase; dUTP pyrophosphatase; desoxyuridine 5'-triphosphate nucleotidohydrolase; desoxyuridine 5'-triphosphatase. Enzyme Commission Number: EC 3.6.1.23. CAS No. 37289-34-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4607; dUTP diphosphatase; EC 3.6.1.23; 37289-34-2; deoxyuridine-triphosphatase; dUTPase; dUTP pyrophosphatase; desoxyuridine 5'-triphosphate nucleotidohydrolase; desoxyuridine 5'-triphosphatase. Cat No: EXWM-4607.