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Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM. Uses: Enzyme inhibitors. Synonyms: Epalrestat; Kinedak; ONO-2235; ONO 2235; ONO2235; Sorbistat. Grades: >98%. CAS No. 82159-09-9. Molecular formula: C15H13NO3S2. Mole weight: 319.4.
Epalrestat
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H13NO3S2. CAS No. 82159-09-9. Prepack ID 65396753-1g. Molecular Weight 319.4. See USA prepack pricing.
Epalrestat
Epalrestat. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-Thiazolidineaceticacid,5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo. CAS No. 82159-09-9. Molecular formula: C15H13NO3S2. Mole weight: 319.4. Purity: ≥98%. Product ID: ACM82159099. Alfa Chemistry ISO 9001:2015 Certified.
Epalrestat
Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO2235. CAS No. 82159-09-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-66009.
Dimer impurity of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: Dimer of 5Z-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid. Grades: > 95%. Molecular formula: C30H26N2O6S4. Mole weight: 638.81.
Epalrestat (E, E)-Isomer
A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-((Z)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40.
Epalrestat (E, Z)-Isomer
A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: (E,Z)-5-(2-Methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40.
Epalrestat (E, Z)-Isomer
Epalrestat (E, Z)-Isomer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((E)-5-((Z)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. CAS No. 124782-64-5. Molecular formula: C15H13NO3S2. Mole weight: 319.40. Catalog: APB124782645.
Epalrestat Impurity 24
Epalrestat Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-5-((E)-2-methyl-3-phenylallylidene)-2-thioxothiazolidin-4-one. CAS No. 15289-56-2. Molecular formula: C13H11NOS2. Mole weight: 261.36. Catalog: APB15289562.
Epalrestat Impurity 25
Epalrestat Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-2-methyl-3-phenylacrylaldehyde. CAS No. 15174-47-7. Molecular formula: C10H10O. Mole weight: 146.19. Catalog: APB15174477.
Epalrestat Impurity 29
Epalrestat Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 15250-29-0. Molecular formula: C10H10O2. Mole weight: 162.19. Catalog: APB15250290.
Epalrestat (Z, Z)-Isomer
Epalrestat (Z, Z)-Isomer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((Z)-5-((Z)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. CAS No. 124782-63-4. Molecular formula: C15H13NO3S2. Mole weight: 319.4. Catalog: APB124782634.
Epalrestat (Z, Z)-Isomer
A stereoisomer of Epalrestat. Epalrestat is a carboxylic acid-based inhibitor of aldose reductase. Synonyms: 2-((Z)-5-((Z)-2-Methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid. Grades: > 95%. Molecular formula: C15H13NO3S2. Mole weight: 319.40.
Epanorin
Epanorin is a lichen metabolite that can inhibit the proliferation of MCF-7 breast cancer cells. Synonyms: L-Leucine, N-[(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)phenylacetyl]-, methyl ester; N-[2-(3-Hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-phenylacetyl]-L-leucine methyl ester; (-)-Epanorin. CAS No. 18463-10-0. Molecular formula: C25H25NO6. Mole weight: 435.47.
EP Chlorpheniramine Maleate Impurity A (2HCl salt form)
An impurity of Chlorpheniramine. Chlorpheniramine is an antihistamine used to prevent symptoms of allergy. It acts via inhibiting histamine produced during anaphylaxis. Synonyms: 2-(4-Chlorophenyl)-4-(dimethylamino)-2-(2-(dimethylamino)ethyl)butanenitrile; 2-(4-Chlorophenyl)-4-(dimethylamino)-2-[2-(dimethylamino)ethyl]butanenitrile dihydrochloride. Grades: 95%. Molecular formula: C16H26Cl3N3. Mole weight: 366.761.
Epcoritamab
Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20 + tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GEN3013. CAS No. 2134641-34-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99931.
EPDM
EPDM. Group: Polymers. CAS No. 25038-36-2.
EPDM chip
EPDM chip. Group: Polymers.
EPDM Rubber
EPDM Rubber. Group: Polymers.
Epelmycin A
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2alpha,5beta(2S*,6R*),6beta))-tetrahydro-6-methyl-5-((tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-25-0. Molecular formula: C42H53NO15. Mole weight: 811.87.
Epelmycin B
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 11-Hydroxyauramycin B. CAS No. 107807-24-9. Molecular formula: C42H51NO16. Mole weight: 825.85.
Epelmycin C
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-23-8. Molecular formula: C36H45NO14. Mole weight: 715.74.
Epelmycin D
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: Violamycin A4; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester. CAS No. 107807-22-7. Molecular formula: C30H35NO11. Mole weight: 585.60.
Epelmycin E
It is produced by the strain of Streptomyces violaceus A262. It has anti-gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin. Synonyms: 11-Hydroxyaclacinomycin A; 1-Naphthacenecarboxylic acid,1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,12-tetrahydroxy-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; sigma-Rmn-A; epsilon-RMN-A. CAS No. 76264-93-2. Molecular formula: C42H53NO16. Mole weight: 827.87.
Epelsiban
Epelsiban is an oxytocin receptor antagonist under the developement of GlaxoSmithKline. It has high affinity for the oxytocin receptor (Ki = 0.13 nM) with >31,000-fold selectivity over the related vasopressin receptors. No development was reported about Phase II clinical tirals for the treatment of premature ejaculation. Uses: Premature ejaculation. Synonyms: GSK-557296; GSK 557296; GSK557296; GSK-557,296-B;(3R,6R)-6-((S)-sec-butyl)-3-(2,3-dihydro-1H-inden-2-yl)-1-((R)-1-(2,6-dimethylpyridin-3-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione;1159097-48-9(besylate). Grades: 98%. CAS No. 872599-83-2. Molecular formula: C30H38N4O4. Mole weight: 518.65.
Epelsiban besylate
This active molecular, also known as GSK-557296B is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity over the related vasopressin receptors. GlaxoSmithKline developed it for the treatment of premature ejaculation in men and also as an agent to enhance embryo or blastocyst implantation in women undergoing embryo or blastocyst transfer associated with in vitro fertilization. In Jul 1st 2016, Phase-II clinical trials in Adenomyosis in USA was on going. In Jun 13th 2016, GlaxoSmithKline terminated phase I trial in Infertility (In volunteers) in USA. Uses: Adenomyosis;infertility; premature ejaculation. Synonyms: (3R,6R)-3-(2,3-Dihydro-1H-inden-2-yl)-1-((1R)-1-(2,6-dimethylpyridin-3-yl)-2- (morpholin-4-yl)-2-oxoethyl)-6-((1S)-1-methylpropyl)piperazine-2,5-dione monobenzenesulfonate,UNII-H629P9T4UN; UNII-H629P9T4UN; GSK557296B; GSK-557296B; 872599-83-2(free base). Grades: 98%. CAS No. 1159097-48-9. Molecular formula: C36H44N4O7S. Mole weight: 676.83.
Eperezolid
Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent, Eperezolid demonstrated good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml). Synonyms: PNU-100592; PNU100592; PNU 100592. Grades: >98%. CAS No. 165800-04-4. Molecular formula: C18H23FN4O5. Mole weight: 394.4.
Eperezolid
Eperezolid(PNU-100592) is a oxazolidinone antibacterial agent, Eperezolid demonstrated good in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml). Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-100592. CAS No. 165800-04-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10393.
Eperezolid
Eperezolid is a bioavailable synthetic antimicrobial agent with spectra of activity against antibiotic-susceptible and -resistant gram-positive pathogens. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Eperezolid; PNU 100592; PNU-100592; PNU100592; U 100592; U-100592; U-100592. Product Category: Others. Appearance: Solid powder. CAS No. 165800-04-4. Molecular formula: C18H20FN4O5. Mole weight: 391.38. Purity: >98%. IUPACName: Acetamide, N-((3-(3-fluoro-4-(4-(hydroxyacetyl)-1-piperazynyl)phenyl)- 2-oxo-5-oxazolidinyl)methyl)-, (S)-. Canonical SMILES: CC(NC[C@H]1CN(C2=CC=C(C3C#[N]CCN3C(CO)=O)C(F)=C2)C(O1)=O)=O. Product ID: ACM165800044. Alfa Chemistry ISO 9001:2015 Certified.
Eperisone-d10 Hydrochloride
Labeled Eperisone. A spasmolytic agent related structurally to Tolperisone. Muscle relaxant (skeletal). Group: Biochemicals. Alternative Names: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl-d10)-1-propanone Hydrochloride; 4'-Ethyl-2-methyl-3-(piperidino-d10)propiophenone Hydrochloride; E 0646-d10; EMPP-d10; Mional-d10; Myonal-d10. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Eperisone HCl
Eperisone relaxes both skeletal muscles and vascular smooth muscles. Uses: Anticonvulsants. Synonyms: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride. Grades: > 95%. CAS No. 56839-43-1. Molecular formula: C17H25NO. HCl. Mole weight: 259.39 36.46.
Eperisone hydrochloride
Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an orally active antispastic agent with a vasodilator effect, used for the research of muscle stiffness and pain. Eperisone Hydrochloride is a potent and selectively P2X7 receptor antagonist, also shows antagonism for human P2X3. Eperisone Hydrochloride works by relaxing both skeletal muscles and vascularsmooth muscles, demonstrating a variety of effects such as reduction ofmyotonia, improvement of circulationand and suppression of the pain reflex [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Eperisone hydrochloride. CAS No. 56839-43-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1901.
Eperisone Hydrochloride
A spasmolytic agent related structurally to Tolperisone. Muscle relaxant (skeletal). Group: Biochemicals. Alternative Names: 1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone Hydrochloride; 4'-Ethyl -2- methyl -3-piperidinopropiophenon e Hydrochloride; E 0646; EMPP; Mional; Myonal. Grades: Highly Purified. CAS No. 56839-43-1. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Eperisone impurity 8
Eperisone impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026-87-5. Molecular formula: C16H24ClNO. Mole weight: 281.82. Catalog: APB1026875.
Epertinib
Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib; S-22611; S22611; S 22611; (R, Z) -1- (4- ( (3-chloro-4- ( (3-fluorobenzyl) oxy) phenyl) amino) quinazolin-6-yl) but-2-yn-1-one O-morpholin-3-ylmethyl oxime; Epertinib; S-222611; S222611; S 222611; 2-Butyn-1-one, 1-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, O-((3R)-3-morpholinylmethyl)oxime, (1Z)-; N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}- 6-[(1Z)-N-{[(3R)-morpholin-3-yl]methoxy}but- 2-ynimidoyl]quinazolin-4-amine. CAS No. 908305-13-5. Molecular formula: C30H27ClFN5O3. Mole weight: 559.178.
Epetirimod
Epetirimod is a small-molecule immune-response modifier intended for the topical treatment of cervical human papilloma virus (HPV) infection and cervical dysplasia. Synonyms: S-30563; S 30563; S30563; 1-(2-methylpropyl)imidazo[4,5-c][1,5]naphthyridin-4-amine; Epetirimod. Grades: >98%. CAS No. 227318-71-0. Molecular formula: C13H15N5. Mole weight: 241.298.
Epetraborole HCl
This active molecular is a selective leucyl-tRNA synthetase inhibitor under the development of Anacor Pharmaceuticals and GlaxoSmithKline as a novel boron-containing antibiotic. Epetraborole was applicated in treatment of infections caused by multidrug-resistant Gram-negative pathogens. All Clostridium perfringens strains had Epetraborole MICs of >32 μg/ml. In Oct 2012, Phase-II for Urinary tract infections in Russia was discontinued. In Mar 2013, Phase-II for Gram-negative infections in USA was Suspended. Uses: Urinary tract infections;gram-negative infections. Synonyms: UNII-MM0NZY12FA; MM0NZY12FA;SCHEMBL1980656; CHEMBL3527377;3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol;hydrochloride; AN-3365; GSK-052; AN 3365; GSK 052; AN3365; GSK052. Grades: 98%. CAS No. 1234563-16-6. Molecular formula: C11H17BClNO4. Mole weight: 373.52.
Epetraborole hydrochloride
Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2251052 hydrochloride. CAS No. 1234563-16-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12479A.
A pyrrolyl benzoic acid that effectively competes against ephrin-B3 for EphA4 binding as well as against ephrin-A1/-A2/-A3/-A5 for EphA2 and EphA4 binding by targeting EphA2/A4 high affinity ephrin-binding pocket in a reversible manner, exhibiting much reduced or no potency against ephrin-A4 for EphA2/EphA4 binding, ephrin-A5 for EphA3/A5/A6/A7 binding, ephrin-B2 for B1/B2/B3/B4/B6 binding, or ephrin-B2 for EphA4 binding. Shown to inhibit ephrin-A1-induced EphA2 phosphorylation (by 92% at 200uM) and ephrin-A5-induced EphA4 phosphorylation (by 79% at 400uM) in cultures in vitro and prevent ephrin-A5-induced growth cone collapse of neurons in 6-d chicken embryo retina (by 100% at 400uM) ex vivo, as well as rescue human mutant SOD-1 A4V transgene-induced axonopathy in zebrafish embryos (500uM from 6 to 30hpf) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
The product immediately hydrolyses to methylamine and 1-hydroxy-1-phenylpropan-2-one. Acts on a number of related compounds including (-)-sympatol, (+)-pseudoephedrine and (+)-norephedrine. Group: Enzymes. Enzyme Commission Number: EC 1.5.1.18. CAS No. 73508-06-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1499; ephedrine dehydrogenase; EC 1.5.1.18; 73508-06-2. Cat No: EXWM-1499.
Ephedrine Hydrochloride racemic
Ephedrine Hydrochloride racemic. Uses: For analytical and research use. Group: Api standards. Catalog: APS007964. Format: Neat. Shipping: Room Temperature.
Ephedrine hydrochloride (racemic) - Drug Precursor
Ephedrine hydrochloride (racemic) - Drug Precursor. Uses: For analytical and research use. Group: European pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: (1RS,2SR)-2-(methylamino)-1-phenylpropan-1-ol hydrochloride,Ephedrine hydrochloride racemic. CAS No. 134-71-4. IUPAC Name: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;hydrochloride. Molecular formula: C10H15NO.ClH. Mole weight: 201.69. Catalog: APS134714. SMILES: Cl.CN[C@@H](C)[C@H](O)c1ccccc1. Format: Neat. Shipping: Room Temperature.
Ephedrine Sulphate
Ephedrine Sulphate. Uses: For analytical and research use. Group: Api standards; impurity standards; pharmaceutical toxicology. Alternative Names: Pseudoephedrine Imp. A (EP), Ephedrine Sulphate, Pseudoephedrine Hydrochloride Imp. A (EP) as Sulphate,Pseudoephedrine Hydrochloride Imp. A (EP). CAS No. 134-72-5. IUPAC Name: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;sulfuric acid. Molecular formula: 2C10H15NO.H2O4S. Mole weight: 428.54. Catalog: APS134725. SMILES: CN[C@@H](C)[C@H](O)c1ccccc1.CN[C@@H](C)[C@H](O)c2ccccc2.OS(=O)(=O)O. Format: Neat. Shipping: Room Temperature.