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| Product | Description | |
|---|---|---|
| FGF-21 murine | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| FGF-22 human | recombinant, expressed in E. coli, ?97% (SDS-PAGE), ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FGF-23 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Fgf-2 from mouse | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Fgf-2 from rat | recombinant, expressed in E. coli, ?97% (SDS-PAGE), ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FGF-2 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FGF-401 | FGF-401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) (IC50 = 1.9 nM) developed for the treatment of solid tumor. Synonyms: FGF401; FGF-401; FGF 401; roblitinib; N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide. CAS No. 1708971-55-4. Molecular formula: C25H30N8O4. Mole weight: 506.56. |  |
| FGF-4 human | Animal-component free, recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FGF-8 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Fgf-9 from rat | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FGF-9 human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| FGF-9, murine Fgf-9 from mouse | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FGF-acidic from mouse | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| FGF-acidic human | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| FGF-ACIDIC rat | recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FGF basic (93-110) (human, bovine) | FGF basic (93-110) (human, bovine). Synonyms: FK18; H-Phe-Phe-Phe-Glu-Arg-Leu-Glu-Ser-Asn-Asn-Tyr-Asn-Thr-Tyr-Arg-Ser-Arg-Lys-OH; L-phenylalanyl-L-phenylalanyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-leucyl-L-alpha-glutamyl-L-seryl-L-asparagyl-L-asparagyl-L-tyrosyl-L-asparagyl-L-threonyl-L-tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysine. Grade: ≥95%. CAS No. 1807793-49-2. Molecular formula: C107H155N31O31. Mole weight: 2371.57. | |
| FGF-basic human | Animal-component free, recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| FGF/PDGF/VEGF RTK Inhibitor - CAS 144335-37-5 | The FGF/PDGF/VEGF RTK Inhibitor, also referenced under CAS 144335-37-5, controls the biological activity of FGF/PDGF/VEGF RTK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR1/DDR2 inhibitor 1 | FGFR1/DDR2 inhibitor 1 is an orally active fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2) inhibitor, with IC50s of 31.1 and 3.2 nM, respectively. It has antitumor activity. Synonyms: 3-(3-(1-Cyclopropyl-1H-pyrazol-4-yl)-1H-indazol-6-yl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide; Benzamide, 3-[3-(1-cyclopropyl-1H-pyrazol-4-yl)-1H-indazol-6-yl]-4-methyl-N-[3-(trifluoromethyl)phenyl]-. Grade: ≥95%. CAS No. 2308497-58-5. Molecular formula: C28H22F3N5O. Mole weight: 501.50. | |
| FGFR1 (FLT2) (399-822), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR1 inhibitor-2 | FGFR1 inhibitor-2, an inhibitor of FGFR1 (IC50 = 4.55 μM in MDA-MB-231 cells), is used in the study of metastatic triple-negative breast cancer. Synonyms: Urea, N-[5,5-bis(4-fluorophenyl)pentyl]-N'-[4-nitro-3-(trifluoromethyl)phenyl]-. CAS No. 2410612-08-5. Molecular formula: C25H22F5N3O3. Mole weight: 507.45. | |
| FGFR1 (V561M), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR2 (285-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?80% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR2-IN-2 | FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2677709-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145231. |  |
| FGFR3 (397-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR3 (K650E), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR4 (460-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?80% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR4-IN-1 | FGFR4-IN-1 is a potent and selective FGFR4 inhibitor. FGFR4 may be a novel therapeutic target for gastric cancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FGFR4-IN-1; FGFR4-IN1; FGFR4-IN 1. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1708971-72-5. Molecular formula: C24H27N7O5. Mole weight: 493.52. Purity: >98%. IUPACName: N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((3-oxomorpholino)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide. Canonical SMILES: O=C(N1CCCC2=CC(CN3C(COCC3)=O)=C(C=O)N=C12)NC4=NC=C(C#N)C(NCCOC)=C4. Product ID: ACM1708971725. Alfa Chemistry ISO 9001:2015 Certified. |  |
| FGFR4-IN-1 | FGFR4-IN-1 is a potent and selective FGFR4 inhibitor with potential for the treatment of gastric cancer. Synonyms: N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((3-oxomorpholino)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide; FGFR4-IN-1; FGFR4-IN1; FGFR4-IN 1. CAS No. 1708971-72-5. Molecular formula: C24H27N7O5. Mole weight: 493.52. | |
| FGFR4-IN-4 | FGFR4-IN-4 is an inhibitor of FGFR4 with antitumor activity. (Extracted from patent WO2018113584A1). Synonyms: N-((3R,4S)-4-((6-(2,6-Dichloro-3,5-dimethoxyphenyl)-8-(4-methoxypiperidin-1-yl)pyrido[3,4-d]pyrimidin-2-yl)amino)tetrahydrofuran-3-yl)acrylamide; 2-Propenamide, N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(4-methoxy-1-piperidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-3-furanyl]-. Grade: ≥95%. CAS No. 2230973-67-6. Molecular formula: C28H32Cl2N6O5. Mole weight: 603.50. | |
| FGFR4-IN-5 | FGFR4-IN-5, a potent and selective covalent FGFR4 inhibitor (IC50 = 6.5 nM), has strong antitumor activity in vivo and can be used in hepatocellular carcinoma studies. Synonyms: 2-Propenamide, N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-7,8-dihydro-8-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]tetrahydro-3-furanyl]-; N-[(3R,4S)-4-{[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}tetrahydro-3-furanyl]acrylamide. Grade: ≥98%. CAS No. 1628793-01-0. Molecular formula: C23H23Cl2N5O5. Mole weight: 520.37. | |
| FGF Receptor Tyrosine Kinase Inhibitor - CAS 192705-79-6 | The FGF Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 192705-79-6, controls the biological activity of FGF Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 - CAS 949164-80-1 | The FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 controls the biological activity of FGF Receptor Tyrosine KInase. Primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| FGFR-IN-1 | FGFR-IN-1 is a potent FGFR inhibitor with an IC 50 of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1513860-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145043. | |
| FGFR-IN-1 | FGFR-IN-1 is a potent inhibitor of FGFR with IC50s of <100 nM for FGFR1, FGFR2 and FGFR3, respectively. (Extracted from patent US20130338134A1, example 219). Synonyms: 2H-Pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-8-(hydroxymethyl)-7-(phenylsulfonyl)-; 3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(hydroxymethyl)-7-(phenylsulfonyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one. Grade: ≥95%. CAS No. 1513860-41-7. Molecular formula: C26H24F2N4O6S. Mole weight: 558.55. | |
| FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 - CAS 219580-11-7 | The FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 controls the biological activity of FGF/VEGF Receptor Tyrosine Kinase. Primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| FGH10019 | FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM, 5-10 times lower than the IC50 of fatostatin (~10 μM). Synonyms: FGH10019; FGH 10019; FGH-10019. Grade: >98%. CAS No. 1046045-61-7. Molecular formula: C18H19N3O2S2. Mole weight: 373.49. | |
| FGI-106 | FGI-106, a potent and broad-spectrum inhibitor, has inhibitory activity against a variety of viruses with EC50s of 100, 800 and 400-900 nM against Ebola, Rift Valley and Dengue Fever viruses, respectively. It also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 and 150 nM, respectively. Synonyms: Quino[8,7-h]quinoline-1,7-diamine, N1,N7-bis[3-(dimethylamino)propyl]-3,9-dimethyl-; N,N'-Bis[3-(dimethylamino)propyl]-3,9-dimethylquinolino[8,7-h]quinoline-1,7-diamine; NSC-306365; N1,N7-Bis[3-(dimethylamino)propyl]-3,9-dimethylquino[8,7-h]quinoline-1,7-diamine. Grade: ≥95%. CAS No. 501081-38-5. Molecular formula: C28H38N6. Mole weight: 458.64. | |
| FGIN 1-27 | FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a K i of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142720-24-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101059. | |
| FGIN-1-27 | FGIN-1-27. Group: Biochemicals. Grades: Purified. CAS No. 142720-24-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| FGIN-1-27 | FGIN-1-27 is a high affinity agonist of mitochondrial benzodiazepine receptors (PBR) binding to benzodiazepine receptors on mitochondrial membranes. FGIN-1-27 indirectly potentiates GABAA receptor signaling to exhibit anticonvulsant, anxiolytic, and sedative activity in both animal and clinical models. Synonyms: FGIN-1-27; FGIN 1 27; FGIN-1 27; FGIN 1-27; FGIN127; N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide; 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide. Grade: ≥98% by HPLC. CAS No. 142720-24-9. Molecular formula: C28H37FN2O. Mole weight: 436.61. | |
| FGIN-1-43 | FGIN-1-43 is a potent and specific ligand for the mitochondial DBI receptor (MDR). Synonyms: FGIN-1-43; FGIN 1 43; FGIN 1-43; FGIN-1 43; FGIN143; N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetamide; 2-[5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide. Grade: ≥98%. CAS No. 145040-29-5. Molecular formula: C28H36Cl2N2O. Mole weight: 487.51. | |
| FGIN-1-43 | FGIN-1-43. Group: Biochemicals. Grades: Purified. CAS No. 145040-29-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FGL peptide | FGL, a NCAM (neural cell adhesion molecule) mimetic peptide, binds to the Fibroblast Growth Factor Receptor 1 (FGFR-1) and has been shown to improve normal memory functioning and mitigate certain pathological cognitive impairments. While FGL does not affect basal synaptic transmission, it facilitates both the induction and maintenance of long-term potentiation (LTP). Additionally, FGL influences heterosynaptic plasticity at adjacent lateral perforant path synapses. Synonyms: H-Glu-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala-OH; L-Alanine, L-α-glutamyl-L-valyl-L-tyrosyl-L-valyl-L-valyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-glutaminyl-L-glutaminylglycyl-L-lysyl-L-seryl-L-lysyl-; L-α-Glutamyl-L-valyl-L-tyrosyl-L-valyl-L-valyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-glutaminyl-L-glutaminylglycyl-L-lysyl-L-seryl-L-lysyl-L-alanine; FGL; FGL (peptide). Grade: ≥95%. CAS No. 499993-62-3. Molecular formula: C71H116N20O25. Mole weight: 1649.80. | |
| FGR, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FGTI-2734 | FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor. It can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FGTI-2734; FGTI2734; FGTI 2734. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1247018-19-4. Molecular formula: C26H31FN6O2S. Mole weight: 510.63. Purity: >98%. IUPACName: N-(2-((4-cyano-2-fluorophenyl)((1-methyl-1H-imidazol-5-yl)methyl)amino)ethyl)-N-(cyclohexylmethyl)pyridine-2-sulfonamide. Canonical SMILES: O=S(C1=NC=CC=C1)(N(CC2CCCCC2)CCN(CC3=CN=CN3C)C4=CC=C(C=C4F)C#N)=O. Product ID: ACM1247018194. Alfa Chemistry ISO 9001:2015 Certified. | |
| FGTI-2734 | FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively. FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1247018-19-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128350. | |
| FH1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FH1 | FH1 (NSC 12407) enhances hepatocyte functions, and promotes the differentiation of induced pluripotent stem (iPS)-derived hepatocytes toward a phenotype more mature and the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 12407; BRD-K4477. CAS No. 2719-5-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12346. | |
| FH 1 | FH 1. Group: Biochemicals. Grades: Purified. CAS No. 2719-5-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FH535 | FH535 is a Wnt/β-catenin signaling inhibitor. It was shown to inhibit proliferation and motility of various cancer stem cells including liver cancer stem cells and colon cancer cells. Synonyms: 2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide. Grade: >98%. CAS No. 108409-83-2. Molecular formula: C13H10Cl2N2O4S. Mole weight: 361.20. | |
| FH535 | FH535 is an inhibitor of Wnt/?-catenin and PPAR with anti-tumor activities[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108409-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15721. | |
| FH535 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FH 535 | FH 535. Group: Biochemicals. Grades: Purified. CAS No. 108409-83-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FH535 sodium salt | FH535 sodium salt is a dual inhibitor of peroxisome proliferator-activated receptor (PPAR) and Wnt/β-catenin/TCF/LEF signaling. FH535 inhibits recruitment of the coactivators β-catenin and GRIP1. FH535 is selectively toxic to carcinomas expressing the Wnt/β-Catenin pathway, leading to the inhibition of proliferation and motility of multiple cancer cells. Synonyms: FH535 sodium salt; FH 535 sodium salt; FH-535 sodium salt; (2,5-dichlorophenyl)sulfonyl-(2-methyl-4-nitrophenyl)azanide sodium salt. Grade: 99%. Molecular formula: C13H9Cl2N2NaO4S. Mole weight: 383.18. | |
| FHD-286 | FHD-286 is a potent and selective inhibitor of BRG1 and BRM. It blocks the activity of BRG1 and BRM, thus stops the growth of AML or MDS. Synonyms: FHD 286; FHD286; 1H-Pyrrole-3-carboxamide, N-((1S)-2-((4-(6-((2R,6S)-2,6-dimethyl-4-morpholinyl)-2-pyridinyl)-2-thiazolyl)amino)-1-(methoxymethyl)-2-oxoethyl)-1-(methylsulfonyl)-; N-((S)-1-(4-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-2-yl)thiazol-2-ylamino)-3-methoxy-1-oxopropan-2-yl)-1-(methylsulfonyl)-1H-pyrrole-3-carboxamide; N-[(2S)-1-[[4-[6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]pyridin-2-yl]-1,3-thiazol-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide. CAS No. 2671128-05-3. Molecular formula: C24H30N6O6S2. Mole weight: 562.66. | |
| FHD-609 | FHD-609 is a PROTAC degrader and inhibitor of BRD9 ( Bromodomain-containing protein 9 ). FHD-609 targets to ncBAF , can be used for research of wide range of cancers that contain a mutation in a BAF complex subunit. FHD-609 in combination with Telomelysin or INO5401, may play a role in adrenocortical carcinoma (ACC) treatment. (Blue: BRD9 ligand-6 (HY-49393), Black: linker (HY-168309); Pink: (S)-Deoxy-thalidomide-Br (HY-168308) ) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2676211-64-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153367. | |
| FHN88734 | FHN88734, also known as Z-Asp-CH2-DCB and PASE-1 INHIBITOR V, is an inhibitor of ICE/Ced-3 family proteases. This product has no formal name at the moment. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-Asp-CH2-DCB; PASE-1 INHIBITOR V; FHN88734; FHN-88734; FHN 88734. Product Category: Inhibitors. Appearance: To be determined. CAS No. 153088-73-4. Molecular formula: C20H17Cl2NO7. Mole weight: 454.26. Purity: >98%. IUPACName: (S)-3-(((benzyloxy)carbonyl)amino)-5-((2,6-dichlorobenzoyl)oxy)-4-oxopentanoic acid. Canonical SMILES: ClC1=C(C(OCC([C@@H](NC(OCC2=CC=CC=C2)=O)CC(O)=O)=O)=O)C(Cl)=CC=C1. Product ID: ACM153088734-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| FHT-1015 | FHT-1015 is a selective SMARCA4 (IC50 = 4 nM) and SMARCA2 (IC50 = 5 nM) (also known as BRG1 and BRM) inhibitor. FH-1015 is an allosteric inhibitor that causes conformation change in the BRG1/BRM protein upon interaction with an allosteric site, inhibiting ATPase activity. FH-1015 interferes with tumor cell growth and migration. FH-1015 can be studied in research for uveal melanoma and hematologic cancer[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2368903-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144896. | |
| FHT-2344 | FHT-2344 is a SMARCA4/SMARCA2 ATPase inhibitor with IC 50 values of 0.026 μM and 0.013 μM, respectively. FHT-2344 has anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2468058-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149458. | |
| FHV Coat-(35-49) | It is a peptide extracted from the flock house virus (FHV) coat protein and internalized with maximum efficiency into Chinese hamster ovary (CHO-K1), HeLa, and Jurkat cells. Synonyms: H-Arg-Arg-Arg-Arg-Asn-Arg-Thr-Arg-Arg-Asn-Arg-Arg-Arg-Val-Arg-OH; L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-asparagyl-L-arginyl-L-threonyl-L-arginyl-L-arginyl-L-asparagyl-L-arginyl-L-arginyl-L-arginyl-L-valyl-L-arginine. Grade: ≥95%. Molecular formula: C83H162N50O19. Mole weight: 2164.54. | |
| FHZ | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FI-700 | FI-700 is a novel and potent FLT3 inhibitor with promising antileukemia activity. FI-700 showed a potent IC(50) value against FLT3 kinase at 20 nmol/L in an in vitro kinase assay. FI-700 showed selective growth inhibition against mutant FLT3-expressing leukemia cell lines and primary acute myeloid leukemia cells, whereas it did not affect the FLT3 ligand (FL)-driven growth of Wt-FLT3-expressing cells. Oral administration of FI-700 induced the regression of tumors in a s.c. tumor xenograft model and increased the survival of mice in an i.v. transplanted model. Furthermore, FI-700 treatment eradicated FLT3/ITD-expressing leukemia cells, both in the peripheral blood and in the bone marrow. Synonyms: FI700; FI 700. CAS No. 866883-79-6. Molecular formula: C21H29N9O. Mole weight: 423.53. | |
| Fiacitabine | Fiacitabine is a selective inhibitior of DNA replication of herpes simplex virus(HSV). It was active at much lower concentrations than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine. It was slightly more active against herpes simplex virus type 1 than acycloquanosine and slightly more toxic to normal cells. Uses: Antineoplastic agents. Synonyms: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodocytosine; 5-Iodo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine; FICA; DRG-0077; DRG 0077; DRG0077; FOAC; Fluoroiodoaracytidine; Fluorviodoaracytidine; 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 1-β-D-2'-Fluoroarabino-5-iodocytosine; 2'-Fluoro-5-iodo-1-β-D-arabinofuranosylcytosine; NSC 382097. Grade: ≥95%. CAS No. 69123-90-6. Molecular formula: C9H11FIN3O4. Mole weight: 371.10. | |
| Fialuridine | An antiviral agent; nucleoside analog with antihepatitis B activity. Group: Biochemicals. Alternative Names: 1-(2-Deoxy-2-fluoro- β-D-arabinofuranosyl)-5-iodo-. Grades: Highly Purified. CAS No. 69123-98-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Fialuridine | Fialuridine (FIAU) is a thymidine-based nucleoside analog with antiviral activity. Fialuridine and its metabolites blocks DNA synthesis in human cytomegalovirus and hepatitis B, as well as herpes simplex. Uses: Antiviral agents. Synonyms: 5-Iodo-2'-deoxy-2'-fluoro-beta-D-arabinouridine; FIAU; Fluoroiodoarauracil; 5-Iodo-2'-Fluoroarauracil; NSC 678514; 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione; 1-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-iodouracil. Grade: ≥95%. CAS No. 69123-98-4. Molecular formula: C9H10FIN2O5. Mole weight: 372.09. | |
| Fialuridine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopypharmaceutical toxicology. | |
| Fialuridine | Fialuridine is a nucleoside analog with antiviral activity [1]. Fialuridine shows anti-orthopoxvirus activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FIAU; DRG-0098; NSC 678514. CAS No. 69123-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118122. | |
| Fialuridine 5'-Monophosphate | Fialuridine 5'-Monophosphate (FIAUMP) is the phosphorylated derivative and major metabolite of the antiviral agent Fialuridine. Studies show that purified mammalian DNA polymerases were able to incorporate FIAUMP into the nascent DNA chain during in vitro DNA synthesis. Synonyms: 1-(2-Deoxy-2-fluoro-5-O-phosphono-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione. CAS No. 99891-31-3. Molecular formula: C9H11FIN2O8P. Mole weight: 452.07. | |
| Fianlimab | Fianlimab (REGN3767) is a human monoclonal antibody that targets the immune checkpoint receptor LAG-3 on T cells and has anti-tumour activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3767. CAS No. 2126132-98-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99617. | |
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