A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A fluorescent false neurotransmitter that acts as an optical tracer that inhibits serotonin binding to VMAT2-containing membranes (IC50 = 1uM). Compound has been used to assess the functional status of TH positive neurons by fluorescent measurement of uptatke and release. Group: Biochemicals. Grades: Highly Purified. CAS No. 1004548-96-2. Pack Sizes: 1mg. US Biological Life Sciences.
FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2) , with an IC 50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IOX3; YM311. CAS No. 223387-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15641.
FG-2216
FG-2216, also known as YM311, is an orally bioavailable HIF-prolyl hydroxylase inhibitor. FG-2216 induced significant and reversible Epo induction in vivo. Synonyms: FG 2216; FG2216; YM311; YM-311; YM 311; N-[(1-Chloro-4-hydroxyisoquinolin-3-YL)carbonyl]glycine. Grade: 98%. CAS No. 223387-75-5. Molecular formula: C12H9ClN2O4. Mole weight: 280.66.
FG-3019
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Pamrevlumab; Anti-Human CTGF Recombinant Antibody. CAS No. 946415-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99288.
FG 7142
FG 7142. Group: Biochemicals. Grades: Purified. CAS No. 78538-74-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
FG 7142
FG 7142 is a benzodiazepine inverse agonist and anxiogenic agent. FG 7142 increases tyrosine hydroxylation and upregulates β-adrenoceptors in mouse cerebral cortex. Uses: Anxiogenic agent. Synonyms: FG 7142; FG7142; FG-7142; N-Methyl-β-carboline-3-carboxamide. Grade: ≥99% by HPLC. CAS No. 78538-74-6. Molecular formula: C13H11N3O. Mole weight: 225.25.
FG 7142
FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor ( K i =91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit ( EC 50 = 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK 39106; LSU-65. CAS No. 78538-74-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100991.
FG8119
FG8119 is a novel benzodiazepine agonist. Synonyms: 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one; 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5a)(1,4)benzodiazepine; COMeIB; FG 8119; FG-8119. CAS No. 106447-61-4. Molecular formula: C17H15N5O2. Mole weight: 321.33.
FGF-16 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
FGF-19 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
FGF-1 human
recombinant, expressed in insect cells, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
FGF-20 human
recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
FGF-21 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
FGF-21 murine
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
FGF-22 human
recombinant, expressed in E. coli, ?97% (SDS-PAGE), ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy.
FGF-23 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Fgf-2 from mouse
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Fgf-2 from rat
recombinant, expressed in E. coli, ?97% (SDS-PAGE), ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy.
FGF-2 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
FGF-401
FGF-401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) (IC50 = 1.9 nM) developed for the treatment of solid tumor. Synonyms: FGF401; FGF-401; FGF 401; roblitinib; N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide. CAS No. 1708971-55-4. Molecular formula: C25H30N8O4. Mole weight: 506.56.
FGF-4 human
Animal-component free, recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
FGF-8 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Fgf-9 from rat
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
FGF-9 human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
FGF-9, murine Fgf-9 from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy.
FGF-acidic from mouse
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
FGF-acidic human
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
FGF-ACIDIC rat
recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Animal-component free, recombinant, expressed in E. coli, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
FGF/PDGF/VEGF RTK Inhibitor - CAS 144335-37-5
The FGF/PDGF/VEGF RTK Inhibitor, also referenced under CAS 144335-37-5, controls the biological activity of FGF/PDGF/VEGF RTK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
FGFR1/DDR2 inhibitor 1
FGFR1/DDR2 inhibitor 1 is an orally active fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2) inhibitor, with IC50s of 31.1 and 3.2 nM, respectively. It has antitumor activity. Synonyms: 3-(3-(1-Cyclopropyl-1H-pyrazol-4-yl)-1H-indazol-6-yl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide; Benzamide, 3-[3-(1-cyclopropyl-1H-pyrazol-4-yl)-1H-indazol-6-yl]-4-methyl-N-[3-(trifluoromethyl)phenyl]-. Grade: ≥95%. CAS No. 2308497-58-5. Molecular formula: C28H22F3N5O. Mole weight: 501.50.
FGFR1 inhibitor-2, an inhibitor of FGFR1 (IC50 = 4.55 μM in MDA-MB-231 cells), is used in the study of metastatic triple-negative breast cancer. Synonyms: Urea, N-[5,5-bis(4-fluorophenyl)pentyl]-N'-[4-nitro-3-(trifluoromethyl)phenyl]-. CAS No. 2410612-08-5. Molecular formula: C25H22F5N3O3. Mole weight: 507.45.
FGFR4-IN-1 is a potent and selective FGFR4 inhibitor. FGFR4 may be a novel therapeutic target for gastric cancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FGFR4-IN-1; FGFR4-IN1; FGFR4-IN 1. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1708971-72-5. Molecular formula: C24H27N7O5. Mole weight: 493.52. Purity: >98%. IUPACName: N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((3-oxomorpholino)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide. Canonical SMILES: O=C(N1CCCC2=CC(CN3C(COCC3)=O)=C(C=O)N=C12)NC4=NC=C(C#N)C(NCCOC)=C4. Product ID: ACM1708971725. Alfa Chemistry ISO 9001:2015 Certified.
FGFR4-IN-1
FGFR4-IN-1 is a potent and selective FGFR4 inhibitor with potential for the treatment of gastric cancer. Synonyms: N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((3-oxomorpholino)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide; FGFR4-IN-1; FGFR4-IN1; FGFR4-IN 1. CAS No. 1708971-72-5. Molecular formula: C24H27N7O5. Mole weight: 493.52.
FGFR4-IN-4
FGFR4-IN-4 is an inhibitor of FGFR4 with antitumor activity. (Extracted from patent WO2018113584A1). Synonyms: N-((3R,4S)-4-((6-(2,6-Dichloro-3,5-dimethoxyphenyl)-8-(4-methoxypiperidin-1-yl)pyrido[3,4-d]pyrimidin-2-yl)amino)tetrahydrofuran-3-yl)acrylamide; 2-Propenamide, N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-(4-methoxy-1-piperidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-3-furanyl]-. Grade: ≥95%. CAS No. 2230973-67-6. Molecular formula: C28H32Cl2N6O5. Mole weight: 603.50.
FGFR4-IN-5
FGFR4-IN-5, a potent and selective covalent FGFR4 inhibitor (IC50 = 6.5 nM), has strong antitumor activity in vivo and can be used in hepatocellular carcinoma studies. Synonyms: 2-Propenamide, N-[(3R,4S)-4-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-7,8-dihydro-8-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]tetrahydro-3-furanyl]-; N-[(3R,4S)-4-{[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}tetrahydro-3-furanyl]acrylamide. Grade: ≥98%. CAS No. 1628793-01-0. Molecular formula: C23H23Cl2N5O5. Mole weight: 520.37.
FGF Receptor Tyrosine Kinase Inhibitor - CAS 192705-79-6
The FGF Receptor Tyrosine Kinase Inhibitor, also referenced under CAS 192705-79-6, controls the biological activity of FGF Receptor Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 - CAS 949164-80-1
The FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 controls the biological activity of FGF Receptor Tyrosine KInase. Primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
FGFR-IN-1
FGFR-IN-1 is a potent inhibitor of FGFR with IC50s of <100 nM for FGFR1, FGFR2 and FGFR3, respectively. (Extracted from patent US20130338134A1, example 219). Synonyms: 2H-Pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-8-(hydroxymethyl)-7-(phenylsulfonyl)-; 3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(hydroxymethyl)-7-(phenylsulfonyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one. Grade: ≥95%. CAS No. 1513860-41-7. Molecular formula: C26H24F2N4O6S. Mole weight: 558.55.
FGFR-IN-1
FGFR-IN-1 is a potent FGFR inhibitor with an IC 50 of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1513860-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145043.
FGF@-STAB - Skin Care Active Ingredient / Anti-Wrinkle
Enantis’ FGF2-STAB® – Stabilized Fibroblast Growth Factor 2 Polypeptide. FGF2-STAB® is a next-generation, patented growth factor developed by Enantis to address one of formulation’s greatest challenges — instability. Unlike traditional FGF2, which rapidly degrades, FGF2-STAB® features a novel peptide sequence engineered for outstanding thermal and biological stability, ensuring longer shelf life, easier formulation, and superior performance. FGF2-STAB® enhances the stability of native FGF2, a key signaling peptide involved in skin regeneration pathways. While isolated FGF2 loses efficacy over time, Enantis’ HYPERSTABLE Growth Factors deliver sustained activity and reliability for advanced cosmetic applications.
United States and all of its trading partners..
FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 - CAS 219580-11-7
The FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 controls the biological activity of FGF/VEGF Receptor Tyrosine Kinase. Primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
FGH10019
FGH10019 is a novel sterol regulatory element-binding protein (SREBP) inhibitor with IC50 of 1 μM, 5-10 times lower than the IC50 of fatostatin (~10 μM). Synonyms: FGH10019; FGH 10019; FGH-10019. Grade: >98%. CAS No. 1046045-61-7. Molecular formula: C18H19N3O2S2. Mole weight: 373.49.
FGI-106
FGI-106, a potent and broad-spectrum inhibitor, has inhibitory activity against a variety of viruses with EC50s of 100, 800 and 400-900 nM against Ebola, Rift Valley and Dengue Fever viruses, respectively. It also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 and 150 nM, respectively. Synonyms: Quino[8,7-h]quinoline-1,7-diamine, N1,N7-bis[3-(dimethylamino)propyl]-3,9-dimethyl-; N,N'-Bis[3-(dimethylamino)propyl]-3,9-dimethylquinolino[8,7-h]quinoline-1,7-diamine; NSC-306365; N1,N7-Bis[3-(dimethylamino)propyl]-3,9-dimethylquino[8,7-h]quinoline-1,7-diamine. Grade: ≥95%. CAS No. 501081-38-5. Molecular formula: C28H38N6. Mole weight: 458.64.
FGIN 1-27
FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a K i of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142720-24-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101059.
FGIN-1-27
FGIN-1-27. Group: Biochemicals. Grades: Purified. CAS No. 142720-24-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
FGIN-1-27
FGIN-1-27 is a high affinity agonist of mitochondrial benzodiazepine receptors (PBR) binding to benzodiazepine receptors on mitochondrial membranes. FGIN-1-27 indirectly potentiates GABAA receptor signaling to exhibit anticonvulsant, anxiolytic, and sedative activity in both animal and clinical models. Synonyms: FGIN-1-27; FGIN 1 27; FGIN-1 27; FGIN 1-27; FGIN127; N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide; 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide. Grade: ≥98% by HPLC. CAS No. 142720-24-9. Molecular formula: C28H37FN2O. Mole weight: 436.61.
FGIN-1-43
FGIN-1-43 is a potent and specific ligand for the mitochondial DBI receptor (MDR). Synonyms: FGIN-1-43; FGIN 1 43; FGIN 1-43; FGIN-1 43; FGIN143; N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetamide; 2-[5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide. Grade: ≥98%. CAS No. 145040-29-5. Molecular formula: C28H36Cl2N2O. Mole weight: 487.51.
FGIN-1-43
FGIN-1-43. Group: Biochemicals. Grades: Purified. CAS No. 145040-29-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
FGL peptide
FGL, a NCAM (neural cell adhesion molecule) mimetic peptide, binds to the Fibroblast Growth Factor Receptor 1 (FGFR-1) and has been shown to improve normal memory functioning and mitigate certain pathological cognitive impairments. While FGL does not affect basal synaptic transmission, it facilitates both the induction and maintenance of long-term potentiation (LTP). Additionally, FGL influences heterosynaptic plasticity at adjacent lateral perforant path synapses. Synonyms: H-Glu-Val-Tyr-Val-Val-Ala-Glu-Asn-Gln-Gln-Gly-Lys-Ser-Lys-Ala-OH; L-Alanine, L-α-glutamyl-L-valyl-L-tyrosyl-L-valyl-L-valyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-glutaminyl-L-glutaminylglycyl-L-lysyl-L-seryl-L-lysyl-; L-α-Glutamyl-L-valyl-L-tyrosyl-L-valyl-L-valyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-glutaminyl-L-glutaminylglycyl-L-lysyl-L-seryl-L-lysyl-L-alanine; FGL; FGL (peptide). Grade: ≥95%. CAS No. 499993-62-3. Molecular formula: C71H116N20O25. Mole weight: 1649.80.
FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor. It can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FGTI-2734; FGTI2734; FGTI 2734. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1247018-19-4. Molecular formula: C26H31FN6O2S. Mole weight: 510.63. Purity: >98%. IUPACName: N-(2-((4-cyano-2-fluorophenyl)((1-methyl-1H-imidazol-5-yl)methyl)amino)ethyl)-N-(cyclohexylmethyl)pyridine-2-sulfonamide. Canonical SMILES: O=S(C1=NC=CC=C1)(N(CC2CCCCC2)CCN(CC3=CN=CN3C)C4=CC=C(C=C4F)C#N)=O. Product ID: ACM1247018194. Alfa Chemistry ISO 9001:2015 Certified.
FGTI-2734
FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively. FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1247018-19-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128350.
FH535 is an inhibitor of Wnt/?-catenin and PPAR with anti-tumor activities[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108409-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15721.
FH535
FH535 is a Wnt/β-catenin signaling inhibitor. It was shown to inhibit proliferation and motility of various cancer stem cells including liver cancer stem cells and colon cancer cells. Synonyms: 2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide. Grade: >98%. CAS No. 108409-83-2. Molecular formula: C13H10Cl2N2O4S. Mole weight: 361.20.
FH 535
FH 535. Group: Biochemicals. Grades: Purified. CAS No. 108409-83-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.