A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Transfection Reagent for Fibroblast Cell Lines and Primary Fibroblasts. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1756.
Nevada, Texas, USA
fibrolase
A 23-kDa, non-hemorrhagic enzyme from the venom of the southern copperhead snake (Agkistrodon contortix contortix). In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: fibrinolytic proteinase; Agkistrodon contortrix contortrix metalloproteinase; Agkistrodon contortrix contortrix venom metalloproteinase. Enzyme Commission Number: EC 3.4.24.72. CAS No. 116036-70-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4356; fibrolase; EC 3.4.24.72; 116036-70-5; fibrinolytic proteinase; Agkistrodon contortrix contortrix metalloproteinase; Agkistrodon contortrix contortrix venom metalloproteinase. Cat No: EXWM-4356.
Fibronectin
Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans [1]. Uses: Scientific research. Group: Natural products. CAS No. 86088-83-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3160.
It is a heparin-binding amino acid sequence found in the heparin-binding domain at the carboxy-terminal of fibronectin. Synonyms: Heparin Binding Peptide; H-Trp-Gln-Pro-Pro-Arg-Ala-Arg-Ile-OH; L-tryptophyl-L-glutaminyl-L-prolyl-L-prolyl-L-arginyl-L-alanyl-L-arginyl-L-isoleucine. Grades: ≥97% by HPLC. CAS No. 125720-21-0. Molecular formula: C47H74N16O10. Mole weight: 1023.19.
Fibronectin Adhesion-promoting Peptide acetate
It is a heparin-binding amino acid sequence found in the heparin-binding domain at the carboxy-terminal of fibronectin. Synonyms: Heparin Binding Peptide acetate. Molecular formula: C49H78N16O12. Mole weight: 1083.25.
Fibronectin CS1 Peptide
Fibronectin CS1 Peptide lacks a domain containing Arg-Gly-Asp, and it can effectively inhibit tumor metastasis in both spontaneous and experimental metastatic models. Synonyms: Fibronectin CS-1 Fragment (1978-1985); H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH; L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-seryl-L-threonine; (3S,6S,9S,12S,15S)-15-amino-12-sec-butyl-3-((S)-2-((S)-1-((1S,2R)-1-carboxy-2-hydroxypropylamino)-3-hydroxy-1-oxopropan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-6-(carboxymethyl)-9-isobutyl-2-methyl-5,8,11,14-tetraoxo-4,7,10,13-tetraazaoctadecan-18-oic acid. Grades: ≥95%. CAS No. 136466-51-8. Molecular formula: C38H64N8O15. Mole weight: 872.96.
Fibronectin CS1 Peptide acetate
Fibronectin CS1 Peptide lacks a domain containing Arg-Gly-Asp, and it can effectively inhibit tumor metastasis in both spontaneous and experimental metastatic models. Synonyms: H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH.CH3CO2H; L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-seryl-L-threonine acetic acid. Grades: ≥95%. CAS No. 2760881-56-7. Molecular formula: C40H68N8O17. Mole weight: 933.01.
Fibronectin Fragment III1-C human
recombinant, expressed in E. coli, lyophilized powder, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Fibronectin human foreskin fibroblasts
lyophilized powder, BioReagent, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Fibrostatin A is a proline hydroxylase inhibitor produced by Strptomyces catenulae. Synonyms: L-Cysteine, N-acetyl-S-((5,8-dihydro-1-hydroxy-3-methoxy-7-methyl-5,8-dioxo-2-naphthalenyl)methyl)-. CAS No. 91776-42-0. Molecular formula: C18H19NO7S. Mole weight: 393.41.
Fibrostatin B
Fibrostatin B is a proline hydroxylase inhibitor produced by Strptomyces catenulae. Synonyms: L-Cysteine, N-acetyl-S-((5,8-dihydro-1-hydroxy-3,6-dimethoxy-7-methyl-5,8-dioxo-2-naphthalenyl)methyl)-. CAS No. 91776-48-6. Molecular formula: C19H21NO8S. Mole weight: 423.44.
Fibrostatin C
Fibrostatin C is a proline hydroxylase inhibitor produced by Strptomyces catenulae. Synonyms: N-Acetyl-S-((5,8-dihydro-1-hydroxy-3,6-dimethoxy-5,8-dioxo-2-naphthalenyl)methyl)-L-cysteine. Grades: >98%. CAS No. 91776-47-5. Molecular formula: C18H19NO8S. Mole weight: 409.41.
Fibrostatin D
Fibrostatin D is a proline hydroxylase inhibitor produced by Strptomyces catenulae. Synonyms: L-Cysteine, N-acetyl-S-((5,8-dihydro-1,3-dihydroxy-6-methoxy-7-methyl-5,8-dioxo-2-naphthalenyl)methyl)-. CAS No. 91776-46-4. Molecular formula: C18H19NO8S. Mole weight: 409.41.
Fibrostatin E
Fibrostatin E is a proline hydroxylase inhibitor produced by Strptomyces catenulae. Synonyms: L-Cysteine, N-acetyl-S-((5,8-dihydro-1-hydroxy-7-(hydroxymethyl)-3-methoxy-5,8-dioxo-2-naphthalenyl)methyl)-. CAS No. 91776-44-2. Molecular formula: C18H19NO8S. Mole weight: 409.41.
Fibrostatin F
Fibrostatin F is a proline hydroxylase inhibitor produced by Strptomyces catenulae. Synonyms: L-Cysteine, N-acetyl-S-((5,8-dihydro-3,6-dimethoxy-5,8-dioxo-1-hydroxy-7-(hydroxymethyl)-2-naphthalenyl)methyl)-. CAS No. 91776-45-3. Molecular formula: C19H21NO9S. Mole weight: 439.44.
ficain
The major proteolytic component of the latex of fig, Ficus glabrata. Cysteine endopeptidases with similar properties are present in other members of the large genus Ficus. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: ficin; debricin; higueroxyl delabarre. Enzyme Commission Number: EC 3.4.22.3. CAS No. 9001-33-6. Ficin. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4204; ficain; EC 3.4.22.3; 9001-33-6; ficin; debricin; higueroxyl delabarre. Cat No: EXWM-4204.
Ficain
Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig ( Ficus carica ). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ficin. CAS No. 9001-33-6. Pack Sizes: 1 g. Product ID: HY-P3028.
Ficellomycin
Ficellomycin is a peptide antibiotic produced by Streptomyces ficellus. Activity against gram-positive bacteria. Synonyms: Antibiotic U 47929. Grades: >98%. CAS No. 59458-27-4. Molecular formula: C13H24N6O3. Mole weight: 312.37.
Ficin
Ficin. Group: Molecular Biology. CAS No. 9001-33-6. Pack Sizes: 25g. US Biological Life Sciences.
Worldwide
Ficin froM Fig Tree Latex
Ficin froM Fig Tree Latex. Synonyms: E.C. 3.4.4.12;FIG TREE LATEX;FICIN;EC 3.4.22.3;EC: 3.4.22.3;DIGEST-ALL(TM) 1;FICIN,POWDER;Ficin Agarose from fig tree latex. CAS No. 9001-33-6. Pack Sizes: 1 g. Product ID: CDF4-0051. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; Ficin froM Fig Tree Latex; CDF4-0051; 9001-33-6; 9001-33-6; 9001-33-6. Purity: 0.99. Color: tan. EC Number: 9001-33-6. Physical State: Suspension. Storage: -20°C.
Ficlatuzumab
Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor ( HGF ). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1174900-84-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99196.
Ficlatuzumab
Ficlatuzumab is a humanized monoclonal antibody that binds to hepatocyte growth factor (HGF), resulting in inhibtion of c-Met signaling pathway. Ficlatuzumab has been approved for the treatment of head and neck cancer. CAS No. 1174900-84-5.
Ficoll
Ficoll 400 highly branched nonionic polysucrose. CAS No. 26873-85-8. Product ID: 4-00097. Mole weight: Mw 3-5 105. Properties: ca. 92% sum of glucose, fructose and sucrose ca. 8%. Source : from Cichorium intybus. Reference: Proc. Soc. Exp. Biol. Med.; 221, 281, 1999; Surgery; 126, 54, 1999; Am. J. Vet. Res.; 60, 703, 1999; Biosci. Biotechnol. Biochem.; 63, 104, 1999; Infect. Immun.; 67, 244, 1999; FEMS Immunol. Med. Microbiol.; 21, 171, 1998; Biochem. J., 114, 557, 1967; Che.
Ficoll
Ficoll 70 highly branched nonionic polysucrose. Water treatment for organic and heavy metal pollutants, biomedical devices, biodegradable packaging, textile finishing for water permeable fabrics, cosmetics. CAS No. 72146-89-5. Product ID: 4-00661. Mole weight: Mw 7 104 Da.
Ficoll ® 400
25g Pack Size. Group: Analytical Reagents, Carbohydrates, Diagnostic Raw Materials. Formula: [C12H22O11. C3H5ClO]n. CAS No. 26873-85-8. Prepack ID 24153174-25g. Molecular Weight ca 400,000. See USA prepack pricing.
Ficonalkib is a potent inhibitor of Anaplastic lymphoma kinase (ALK) , the tyrosine kinase receptor. Ficonalkib, can be used as an antineoplastic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2233574-95-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152845.
FICT-FF-FMK
FICT-FF-FMK is a fluorescein isothiocyanate (FITC)-conjugated inhibitor of cathepsin B and cathepsin L, which can be used for detecting cathepsin B and cathepsin L in live cells. Synonyms: FICT-Phe-Phe-FMK; FICT-Phe-Phe-Fluoromethylketone. Grades: >95%. Molecular formula: C41H34FN3O6S. Mole weight: 715.80.
FICZ
FICZ. Group: Biochemicals. Grades: Purified. CAS No. 172922-91-7. Pack Sizes: 1mg. US Biological Life Sciences.
High affinity aryl hydrocarbon receptor (AhR) agonist (Kd = 70 p M). Proposed to be an endogenous AhR ligand. Induces transient expression of cytochrome P450-1A1 (CYP1A1) in vitro. Synonyms: Indolo[3,2-b]carbazole-6-carboxaldehyde, 5,11-dihydro-; 5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde; 6-Formylindolo[3,2-b]carbazole. Grades: >98%. CAS No. 172922-91-7. Molecular formula: C19H12N2O. Mole weight: 284.31.
Fidarestat
Fidarestat is a aldose reductase inhibitor originated by Sanwa Kagaku Kenkyusho. It was very effective in significantly alleviating some symptoms of diabetic polyneuropathy. Long-term treatment with SNK-860 has a beneficial preventive effect on the development of experimental diabetic neuropathy. In addition, Fidarestat is also a promising drug targeting autophagy in Colorectal Carcinoma. Uses: Diabetic neuropathies. Synonyms: SNK860; SNK-860; SNK 860; SK860; SK-860; SK 860; Fidarestat; Aldos. (2S,4S)-6-fluoro-2',5'-dioxospiro[chromane-4,4'-imidazolidine]-2-carboxamide; Aldos;SNK 860. Grades: 98%. CAS No. 136087-85-9. Molecular formula: C12H10FN3O4. Mole weight: 279.23.
Fidarestat
Fidarestat (SNK 860) is an inhibitor of aldose reductase , with IC 50 s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNK 860. CAS No. 136087-85-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-105185.
Fidaxomicin
?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral moleculesenzyme activators, inhibitors & substrates. Alternative Names: Lipiarmycin, (3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-?-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-?-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaen-2-one, Dificid, Fidaxomicin, PAR 101, Dificlir, OPT 80,Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-?-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-?-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-, (3E,5E,8S,9E,11S,12R,13E,15E,18S)-, Clostomicin B1, R-Tiacumicin B, PAR 01, Lipiarmicin, Tiacumicin B, Lipiarmycin A 3, Fidaxomycin.
Fidaxomicin
Fidaxomicin (OPT-80), a macrocyclic antibiotic , is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti- Clostridium difficile activity (MIC 90 =0.12?μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: OPT-80; PAR-101. CAS No. 873857-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17580.
Fidaxomicin
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C52H74Cl2O18. CAS No. 873857-62-6. Prepack ID 90018462-100mg. Molecular Weight 1058.04. See USA prepack pricing.
Fidaxomicin Impurity 7
Fidaxomicin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4S,5S)-3,5-dihydroxy-4-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. CAS No. 106008-69-9. Molecular formula: C52H74Cl2O18. Mole weight: 1056.43. Catalog: APB106008699.
Fidaxomicin (Lipiarmycin)
Fidaxomicin is a non-absorbed macrocyclic antibiotic, and is the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years. Fidaxomicin works by inhibiting sporulation by CDI, sustaining clinical response and reducing recurrences of this pathogen. Group: Biochemicals. Alternative Names: 3E, 5E, 8S, 9E, 11S, 12R, 13E, 15E, 18S)-3-[[[6-Deoxy-4-O-(3, 5-dichloro-2-ethyl-4, 6-dihydroxybenzoyl)-2-O-methyl- β -D-mannopyranosyl] oxy] methyl] -12- [ [6-deoxy-5-C-methyl-4-O- (2-methyl-1-oxopropyl) - β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one; Clostomicin B1; Dificid; Dificlir; Fidaxomicin; Fidaxomycin; Lipiarmicin; Lipiarmycin; Lipiarmycin A 3; OPT 80; PAR 01; PAR 101; R-Tiacumicin B; Tiacumicin. Grades: Highly Purified. CAS No. 873857-62-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??Cl?O??, Molecular Weight: 1058.04. US Biological Life Sciences.
Worldwide
Fidaxomicin Metabolite OP-1118
Fidaxomicin Metabolite OP-1118. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxo-12-(((2R,3S,4S,5S)-3,4,5-trihydroxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. CAS No. 1030825-28-5. Molecular formula: C48H68Cl2O17. Mole weight: 986.38. Catalog: APB1030825285.
Fidrisertib
ALK2-IN-1 is a activin receptor-like kinase-2 ( ALK2 ) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC 50 of <10 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-782; IPN-60130; ALK2-IN-1. CAS No. 2141955-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117887.
Fiduxosin
Fiduxosin is a potent antagonist of α1-adrenoceptor, with Ki= 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively. Fiduxosin was found to have improved uroselectivity relative to tamsulosin. Synonyms: 3-[4-[(3aR,9bR)-9-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-8-phenyl-1H-pyrazino[1,2]thieno[3,4-b]pyrimidine-2,4-dione; 3-(4-(9-methoxy-1,2,3,3a,4,9b-hexahydro(1)benzopyran(3,4-c)pyrrol-2-yl)butyl)-8-phenylpyrazino(2',3'-4,5)thieno(3,2-d)pyrimidine-2,4(1H,3H)-dione; ABT 980; ABT-980; ABT980; fiduxosin. CAS No. 208993-54-8. Molecular formula: C30H29N5O4S. Mole weight: 555.65.
Fiduxosin hydrochloride
Fiduxosin hydrochloride is an alpha(1)-adrenoceptor antagonist used for the treatment of benign prostatic hyperplasia. Synonyms: 3-[4-[(3aR,9bR)-9-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-8-phenyl-1H-pyrazino[1,2]thieno[3,4-b]pyrimidine-2,4-dione;hydrochloride; Fiduxosin hydrochloride; Fiduxosin HCl; 208993-54-8 (Fiduxosin) ; 208992-74-9 ( Fiduxosin Hydrochlride). Grades: >98%. CAS No. 208992-74-9. Molecular formula: C30H29N5O4S.HCl. Mole weight: 592.11.
Figitumumab
Figitumumab (CP-751871) is a potent and fully human monoclonal anti - insulin-like growth factor 1 receptor ( IGF1R ) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC 50 of 1.8 nM [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CP-751871. CAS No. 943453-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99197.
Figitumumab
Figitumumab is a monoclonal antibody that targets the insulin-like growth factor type I receptor (IGF1R). Figitumumab binds to IGF1R, resulting in a reduction in receptor expression on tumor cells that express IGF1R and inhibition of tumor growth. Synonyms: CP-751871. CAS No. 943453-46-1.
Fig P.E. 10:1
Fig P.E. 10:1.
CA, FL & NJ
FIIN-1
FIIN-1 is a potent, irreversible and selective FGFR inhibitor with IC50s of 9.2, 6.2, 11.9 and 189 nM against FGFR1/2/3/4, respectively. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8, 6.9, 5.4, 120 nM and 32, 120 nM, respectively. Synonyms: FGFR irreversible inhibitor-1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide. Grades: ≥95%. CAS No. 1256152-35-8. Molecular formula: C32H39Cl2N7O4. Mole weight: 656.60.
FIIN 1 hydrochloride
FIIN 1 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1256152-35-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
FIIN-2
FIIN-2 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547. Synonyms: FIIN2; FIIN 2; FIIN-2. Grades: 98%. CAS No. 1633044-56-0. Molecular formula: C35H38N8O4. Mole weight: 634.73.
FIIN-3
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-3 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547. Synonyms: FIIN3; FIIN 3; FIIN-3. Grades: 98%. CAS No. 1637735-84-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61.
Filaminast is a Type 4 cyclic nucleotide phosphodiesterase inhibitor. It is an analog of rolipram which served as a prototype molecule for several development efforts. In Oct 1999, phase II clinical trials for Asthma in European Union was discontinued. Uses: Asthma. Synonyms: UNII-CDD69JC61J; Way-pda-641; WAY-PDA 641; WAY-PDA-641; CDD69JC61J; SCHEMBL73843; 1-(3-(Cyclopentyloxy)-4-methoxyphenyl)ethanone-(E)-O-(aminocarbonyl)oxime. Grades: 98%. CAS No. 141184-34-1. Molecular formula: C15H20N2O4. Mole weight: 292.33.
Filanesib
Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein ( KSP ) inhibitor, with an IC 50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARRY-520. CAS No. 885060-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15187.
Filanesib
Filanesib, also known as ARRY-520, is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. KSP inhibitor ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Synonyms: ARRY-520; ARRY 520; ARRY520. Grades: 0.98. CAS No. 885060-09-3. Molecular formula: C20H22F2N4O2S. Mole weight: 420.479.
Filapixant
Filapixant is a purinoreceptor antagonist extracted from patent WO2016091776A1, example 348. Filapixant is the active reference substance of Eliapixant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1902607. CAS No. 1948232-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109173.
Filbertone. CAS No. 81925-81-7. FEMA No. 3761. Kosher: Y. VIGON Item # 502978. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Filgotinib
Filgotinib (GLPG0634) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634. CAS No. 1206161-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300.