A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ficonalkib is a potent inhibitor of Anaplastic lymphoma kinase (ALK) , the tyrosine kinase receptor. Ficonalkib, can be used as an antineoplastic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2233574-95-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152845.
FICT-FF-FMK
FICT-FF-FMK is a fluorescein isothiocyanate (FITC)-conjugated inhibitor of cathepsin B and cathepsin L, which can be used for detecting cathepsin B and cathepsin L in live cells. Synonyms: FICT-Phe-Phe-FMK; FICT-Phe-Phe-Fluoromethylketone. Grades: >95%. Molecular formula: C41H34FN3O6S. Mole weight: 715.80.
FICZ
FICZ is a potent aryl hydrocarbon receptor (AhR) agonist with a Kd of 70 pM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 6-Formylindolo[3,2-b]carbazole. CAS No. 172922-91-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12451.
FICZ
FICZ. Group: Biochemicals. Grades: Purified. CAS No. 172922-91-7. Pack Sizes: 1mg. US Biological Life Sciences.
High affinity aryl hydrocarbon receptor (AhR) agonist (Kd = 70 p M). Proposed to be an endogenous AhR ligand. Induces transient expression of cytochrome P450-1A1 (CYP1A1) in vitro. Synonyms: Indolo[3,2-b]carbazole-6-carboxaldehyde, 5,11-dihydro-; 5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde; 6-Formylindolo[3,2-b]carbazole. Grades: >98%. CAS No. 172922-91-7. Molecular formula: C19H12N2O. Mole weight: 284.31.
Fidarestat
Fidarestat is a aldose reductase inhibitor originated by Sanwa Kagaku Kenkyusho. It was very effective in significantly alleviating some symptoms of diabetic polyneuropathy. Long-term treatment with SNK-860 has a beneficial preventive effect on the development of experimental diabetic neuropathy. In addition, Fidarestat is also a promising drug targeting autophagy in Colorectal Carcinoma. Uses: Diabetic neuropathies. Synonyms: SNK860; SNK-860; SNK 860; SK860; SK-860; SK 860; Fidarestat; Aldos. (2S,4S)-6-fluoro-2',5'-dioxospiro[chromane-4,4'-imidazolidine]-2-carboxamide; Aldos;SNK 860. Grades: 98%. CAS No. 136087-85-9. Molecular formula: C12H10FN3O4. Mole weight: 279.23.
Fidarestat
Fidarestat (SNK 860) is an inhibitor of aldose reductase , with IC 50 s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNK 860. CAS No. 136087-85-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-105185.
FIDAS-5
FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 ?M. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391934-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136144.
Fidaxomicin
?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral moleculesenzyme activators, inhibitors & substrates. Alternative Names: Lipiarmycin, (3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-?-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-?-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaen-2-one, Dificid, Fidaxomicin, PAR 101, Dificlir, OPT 80,Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-?-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-?-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-, (3E,5E,8S,9E,11S,12R,13E,15E,18S)-, Clostomicin B1, R-Tiacumicin B, PAR 01, Lipiarmicin, Tiacumicin B, Lipiarmycin A 3, Fidaxomycin.
Fidaxomicin
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C52H74Cl2O18. CAS No. 873857-62-6. Prepack ID 90018462-100mg. Molecular Weight 1058.04. See USA prepack pricing.
Fidaxomicin
Fidaxomicin (OPT-80), a macrocyclic antibiotic , is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti- Clostridium difficile activity (MIC 90 =0.12?μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: OPT-80; PAR-101. CAS No. 873857-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17580.
Fidaxomicin Impurity 7
Fidaxomicin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4S,5S)-3,5-dihydroxy-4-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. CAS No. 106008-69-9. Molecular formula: C52H74Cl2O18. Mole weight: 1056.43. Catalog: APB106008699.
Fidaxomicin (Lipiarmycin)
Fidaxomicin is a non-absorbed macrocyclic antibiotic, and is the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years. Fidaxomicin works by inhibiting sporulation by CDI, sustaining clinical response and reducing recurrences of this pathogen. Group: Biochemicals. Alternative Names: 3E, 5E, 8S, 9E, 11S, 12R, 13E, 15E, 18S)-3-[[[6-Deoxy-4-O-(3, 5-dichloro-2-ethyl-4, 6-dihydroxybenzoyl)-2-O-methyl- β -D-mannopyranosyl] oxy] methyl] -12- [ [6-deoxy-5-C-methyl-4-O- (2-methyl-1-oxopropyl) - β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one; Clostomicin B1; Dificid; Dificlir; Fidaxomicin; Fidaxomycin; Lipiarmicin; Lipiarmycin; Lipiarmycin A 3; OPT 80; PAR 01; PAR 101; R-Tiacumicin B; Tiacumicin. Grades: Highly Purified. CAS No. 873857-62-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??Cl?O??, Molecular Weight: 1058.04. US Biological Life Sciences.
Worldwide
Fidaxomicin Metabolite OP-1118
Fidaxomicin Metabolite OP-1118. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxo-12-(((2R,3S,4S,5S)-3,4,5-trihydroxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. CAS No. 1030825-28-5. Molecular formula: C48H68Cl2O17. Mole weight: 986.38. Catalog: APB1030825285.
Fidrisertib
ALK2-IN-1 is a activin receptor-like kinase-2 ( ALK2 ) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC 50 of <10 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-782; IPN-60130; ALK2-IN-1. CAS No. 2141955-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117887.
Fiduxosin
Fiduxosin is a potent antagonist of α1-adrenoceptor, with Ki= 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively. Fiduxosin was found to have improved uroselectivity relative to tamsulosin. Synonyms: 3-[4-[(3aR,9bR)-9-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-8-phenyl-1H-pyrazino[1,2]thieno[3,4-b]pyrimidine-2,4-dione; 3-(4-(9-methoxy-1,2,3,3a,4,9b-hexahydro(1)benzopyran(3,4-c)pyrrol-2-yl)butyl)-8-phenylpyrazino(2',3'-4,5)thieno(3,2-d)pyrimidine-2,4(1H,3H)-dione; ABT 980; ABT-980; ABT980; fiduxosin. CAS No. 208993-54-8. Molecular formula: C30H29N5O4S. Mole weight: 555.65.
Fiduxosin hydrochloride
Fiduxosin hydrochloride is an alpha(1)-adrenoceptor antagonist used for the treatment of benign prostatic hyperplasia. Synonyms: 3-[4-[(3aR,9bR)-9-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-8-phenyl-1H-pyrazino[1,2]thieno[3,4-b]pyrimidine-2,4-dione;hydrochloride; Fiduxosin hydrochloride; Fiduxosin HCl; 208993-54-8 (Fiduxosin) ; 208992-74-9 ( Fiduxosin Hydrochlride). Grades: >98%. CAS No. 208992-74-9. Molecular formula: C30H29N5O4S.HCl. Mole weight: 592.11.
Figitumumab
Figitumumab is a monoclonal antibody that targets the insulin-like growth factor type I receptor (IGF1R). Figitumumab binds to IGF1R, resulting in a reduction in receptor expression on tumor cells that express IGF1R and inhibition of tumor growth. Synonyms: CP-751871. CAS No. 943453-46-1.
Figitumumab
Figitumumab (CP-751871) is a potent and fully human monoclonal anti - insulin-like growth factor 1 receptor ( IGF1R ) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC 50 of 1.8 nM [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CP-751871. CAS No. 943453-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99197.
Fig P.E. 10:1
Fig P.E. 10:1.
CA, FL & NJ
FIIN-1
FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC50s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FGFR irreversible inhibitor-1. CAS No. 1256152-35-8. Pack Sizes: 2 mg; 5 mg; 10 mg. Product ID: HY-15813.
FIIN-1
FIIN-1 is a potent, irreversible and selective FGFR inhibitor with IC50s of 9.2, 6.2, 11.9 and 189 nM against FGFR1/2/3/4, respectively. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8, 6.9, 5.4, 120 nM and 32, 120 nM, respectively. Synonyms: FGFR irreversible inhibitor-1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide. Grades: ≥95%. CAS No. 1256152-35-8. Molecular formula: C32H39Cl2N7O4. Mole weight: 656.60.
FIIN 1 hydrochloride
FIIN 1 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1256152-35-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
FIIN-2
FIIN-2 is an irreversible inhibitor of FGFR with an IC50 of 3.1, 4.3, 27, and 45 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1633044-56-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18602.
FIIN-2
FIIN-2 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547. Synonyms: FIIN2; FIIN 2; FIIN-2. Grades: 98%. CAS No. 1633044-56-0. Molecular formula: C35H38N8O4. Mole weight: 634.73.
FIIN-3
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-3 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547. Synonyms: FIIN3; FIIN 3; FIIN-3. Grades: 98%. CAS No. 1637735-84-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61.
Filaminast is a Type 4 cyclic nucleotide phosphodiesterase inhibitor. It is an analog of rolipram which served as a prototype molecule for several development efforts. In Oct 1999, phase II clinical trials for Asthma in European Union was discontinued. Uses: Asthma. Synonyms: UNII-CDD69JC61J; Way-pda-641; WAY-PDA 641; WAY-PDA-641; CDD69JC61J; SCHEMBL73843; 1-(3-(Cyclopentyloxy)-4-methoxyphenyl)ethanone-(E)-O-(aminocarbonyl)oxime. Grades: 98%. CAS No. 141184-34-1. Molecular formula: C15H20N2O4. Mole weight: 292.33.
Filanesib
Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein ( KSP ) inhibitor, with an IC 50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARRY-520. CAS No. 885060-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15187.
Filanesib
Filanesib, also known as ARRY-520, is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. KSP inhibitor ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Synonyms: ARRY-520; ARRY 520; ARRY520. Grades: 0.98. CAS No. 885060-09-3. Molecular formula: C20H22F2N4O2S. Mole weight: 420.479.
Filapixant
Filapixant is a purinoreceptor antagonist extracted from patent WO2016091776A1, example 348. Filapixant is the active reference substance of Eliapixant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1902607. CAS No. 1948232-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109173.
Filbertone. CAS No. 81925-81-7. FEMA No. 3761. Kosher: Y. VIGON Item # 502978. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Filgotinib
Filgotinib is a potent and selective JAK1 inhibitor exhibiting 30-fold selectivity over JAK2. It was shown to inhibit Th1 and Th2 differentiation and to a lesser extent the differentiation of Th17 cells in vitro. Filgotinib has the potential for the treatment of rheumatoid arthritis and possibly other immune-inflammatory diseases. Synonyms: GLPG0634; GLPG-0634; N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide. Grades: >98%. CAS No. 1206161-97-8. Molecular formula: C21H23N5O3S. Mole weight: 425.507.
Filgotinib
Filgotinib (GLPG0634) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634. CAS No. 1206161-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300.
Filgotinib maleate
Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib maleate can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values ??of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib maleate also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib maleate can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634 maleate. CAS No. 1802998-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300A.
Filgrastim
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards.
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm)[1][2][3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 11078-21-0. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-N6716.
Filipin complex
Filipin are a mixture of polyene macrolide antibiotics produced by Streptomyces filipinensis and Str. durhamensis. Four components I-IV are separated. Grades: >95% by HPLC. CAS No. 11078-21-0. Molecular formula: C35H58O11 (for Flipin III). Mole weight: 654.8.
Filipin II is a polyene macrolide antibiotic produced by Streptomyces filipinensis and Str. durhamensis. It has anti-fungal activity and has the effect of inhibiting Mycoplasma Lebsiella. It also has an effect on the diseases caused by Aspergillus penicillium, stalk mold and other crops such as peas and tomatoes. Grades: >95% by HPLC. CAS No. 38620-77-8. Molecular formula: C35H58O10. Mole weight: 638.83.
Filipin Iii
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 16,20,22,24-Octacosapentenoic Acid. Product Category: Inhibitors. Appearance: White or light yellow solid. CAS No. 480-49-9. Molecular formula: C35H58O11. Mole weight: 654.83. Purity: 0.98. IUPACName: (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one. Canonical SMILES: CCCCC[C@H](C1[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@@H](/C(=C\\C=C\\C=C\\C=C\\C=C\\[C@@H]([C@H](OC1=O)C)O)/C)O)O)O)O)O)O)O)O. Product ID: ACM480499. Alfa Chemistry ISO 9001:2015 Certified.
Filipin III
Filipin III is a polyene macrolide antibiotic produced by Streptomyces filipinensis and Str. durhamensis. It has anti-fungal activity and has the effect of inhibiting Mycoplasma Lebsiella. It also has an effect on the diseases caused by Aspergillus penicillium, stalk mold and other crops such as peas and tomatoes. Synonyms: 14-Deoxylagosin. Grades: >98%. CAS No. 480-49-9. Molecular formula: C35H58O11. Mole weight: 654.83.
Filipin III
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis , S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-49-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6718.
Filipin III (Filimirasin, Filmirisin)
Filipin III (Filimirasin, Filmirisin). Group: Biochemicals. Alternative Names: (17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one. Grades: Purified. CAS No. 480-49-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C35 H58 O11 , Molecular Weight: 654.8. US Biological Life Sciences.
from Streptomyces filipinensis, 1mg/ml in DMSO based solution. Group: Fluorescence/luminescence spectroscopy.
Filixic acid ABA
Botanical Source: Group: Biochemicals. Alternative Names: Trisalbaspidin ABA. Grades: Plant Grade. CAS No. 38226-84-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Filled PTFE Article
Filled PTFE Article. Group: Polymers.
Film Coatings
Film Coatings. Product ID: PE-0191. Category: Coating Systems Excipients. Product Keywords: Pharmaceutical Excipients; Coating Systems Excipients; Film Coatings; PE-0191. Standard: ChP, USP, BP, EP, JP. Grade: Pharmaceutical grade.
Films
Films. Group: Polymers.
Filociclovir
Filociclovir is a broad-spectrum anti-herpesvirus compound with good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8, with EC50 values ranging from 0.7 μM to 8 μM. Uses: Filociclovir is antiviral drug candidate and is used for the treatment of cytomegalovirus infection. Synonyms: Cyclopropavir; ZSM-I-62; MBX-400; 2-Amino-9-[ (Z) -[2, 2-bis (hydroxymethyl) cyclopropylidene]methyl]-3H-purin-6-one; (Z) -2-amino-9- ( (2, 2-bis (hydroxymethyl) cyclopropylidene) methyl) -1, 9-dihydro-6H-purin-6-one; (Z) -9- ( (2, 2-bis- (Hydroxymethyl) cyclopropylidene) methyl) guanine; (Z) -2-amino-9- ( (2, 2-bis (hydroxymethyl) cyclopropylidene) methyl) -1H-purin-6 (9H) -one. Grades: 98%. CAS No. 632325-71-4. Molecular formula: C11H13N5O3. Mole weight: 263.26.
Filorexant
Filorexant, a selective reversible and orally bioavaliable antagonist of OX(1)R receptor and OX(2)R receptor, could probably be an effective compound in the treatment of insomnia. It is still under the Phase II trial by Merck. Binding Ki: less than 3 nM. Uses: Filorexant, a selective reversible and orally bioavaliable antagonist of ox(1)r receptor and ox(2)r receptor, could probably be an effective compound in the treatment of insomnia. Synonyms: FILOREXANT; MK-6096; UNII-E6BTT8VA5Z; MK6096; MK 6096. Grades: 98%. CAS No. 1088991-73-4. Molecular formula: C24H25FN4O2. Mole weight: 420.48.
Fimaporfin
Fimaporfin, a potent chlorin-based photosensitizer, is consisted of a mixture of three isomers A, B and C (25%,50%,25%). Fimaporfin has been developed by di-imide reduction of disulfonated tetraphenyl porphine (TPPS(2a)). The synthesized TPCS(2a) contains 3 isomers as shown by HPLC with low inter-batch variation with respect to isomer formation, less than 0.5% (w/w) of the starting material TPPS(2a) and absorbs light at 652nm. TPCS(2a) was found to be a clinically suitable PCI photosensitizer for photochemical activation of molecules that do not readily penetrate the cellular plasma membrane. Synonyms: Benzenesulfonic acid, 4,4'-[7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21H,23H-porphine-5,20(or 5,10)-diyl]bis-; 4,4'-[7,8(or 17,18)-Dihydro-10,15(or 15,20)-diphenyl-21H,23H-porphine-5,20(or 5,10)-diyl]bis[benzenesulfonic acid]. CAS No. 1443547-43-0. Molecular formula: C132H96N12O18S6. Mole weight: 2330.63.
Fimasartan
Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BR-A-657. CAS No. 247257-48-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0780.
Fimasartan
Fimasartan is an angiotensin II receptor blocker (ARB) with selectivity for angiotensin II receptor type 1. Fimasartan is approved in South Korea for the treatment of patients with hypertension and heart failure. Synonyms: 2-[2-butyl-4-methyl-6-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidin-5-yl]-N,N-dimethylethanethioamideBR-A657; BR A657; BRA657; BRA 657; Fimasartan. brand name: Kanarb. Grades: >95%. CAS No. 247257-48-3. Molecular formula: C27H31N7OS. Mole weight: 501.6.
Fimasartan Impurity 1
An impurity of Fimasartan. Fimasartan is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Synonyms: 2-(2-Butyl-4-methyl-6-oxo-1-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1,6-dihydro-5-pyrimidinyl)-N,N-dimethylethanethioamide. Grades: > 95%. Molecular formula: C28H33N7OS. Mole weight: 515.69.
Fimasartan Impurity 2
An impurity of Fimasartan. Fimasartan is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Synonyms: 2-butyl-1,?6-dihydro-N,?N,?4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)?-1H-tetrazol-5-yl]?[1,?1'-biphenyl]?-4-yl]?methyl]?-5-Pyrimidineethanethio?amide. Grades: > 95%. CAS No. 1361024-52-3. Molecular formula: C46H45N7OS. Mole weight: 743.98.
Fimepinostat
Fimepinostat (CUDC-907) potently inhibits class I PI3K s as well as classes I and II HDAC enzymes with an IC 50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CUDC-907. CAS No. 1339928-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13522.
FIN56 is a specific inducer of ferroptosis. FIN56 induces ferroptosis by inducing degradation of GPX4. FIN56 also binds to and activates squalene synthase[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1083162-61-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103087.
FIN56
FIN56 is a specific inducer of ferroptosis and causes the loss of GPX4 activity in cell lysates. Synonyms: FIN56; FIN-56; FIN 56. 2-N,7-N-dicyclohexyl-9-hydroxyiminofluorene-2,7-disulfonamide; s8254. CAS No. 1083162-61-1. Molecular formula: C25H31N3O5S2. Mole weight: 517.66.