A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Fidaxomicin (OPT-80), a macrocyclic antibiotic , is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti- Clostridium difficile activity (MIC 90 =0.12?μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: OPT-80; PAR-101. CAS No. 873857-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17580.
Fidaxomicin
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C52H74Cl2O18. CAS No. 873857-62-6. Prepack ID 90018462-100mg. Molecular Weight 1058.04. See USA prepack pricing.
Fidaxomicin Impurity 4
Fidaxomicin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-11-ethyl-8,12-dihydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. Molecular Formula: C41H56Cl2O13. Mole Weight: 826.31. Catalog: APB06319.
Fidaxomicin Impurity 5
Fidaxomicin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2,8-dioxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2,4-dihydroxy-6-methylbenzoate. Molecular Formula: C51H70Cl2O18. Mole Weight: 1040.39. Catalog: APB06320.
Fidaxomicin Impurity 6
Fidaxomicin Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. Molecular Formula: C52H74Cl2O17. Mole Weight: 1040.43. Catalog: APB06318.
Fidaxomicin Impurity 7
Fidaxomicin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4S,5S)-3,5-dihydroxy-4-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. CAS No. 106008-69-9. Molecular Formula: C52H74Cl2O18. Mole Weight: 1056.43. Catalog: APB106008699.
Fidaxomicin Impurity 8
Fidaxomicin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2,4-dihydroxy-6-methylbenzoate. Molecular Formula: C51H72Cl2O18. Mole Weight: 1042.41. Catalog: APB06317.
Fidaxomicin Impurity 9
Fidaxomicin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2,4-dihydroxy-6-isopropylbenzoate. Molecular Formula: C53H76Cl2O18. Mole Weight: 1070.44. Catalog: APB06316.
Fidaxomicin (Lipiarmycin)
Fidaxomicin is a non-absorbed macrocyclic antibiotic, and is the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years. Fidaxomicin works by inhibiting sporulation by CDI, sustaining clinical response and reducing recurrences of this pathogen. Group: Biochemicals. Alternative Names: 3E, 5E, 8S, 9E, 11S, 12R, 13E, 15E, 18S)-3-[[[6-Deoxy-4-O-(3, 5-dichloro-2-ethyl-4, 6-dihydroxybenzoyl)-2-O-methyl- β -D-mannopyranosyl] oxy] methyl] -12- [ [6-deoxy-5-C-methyl-4-O- (2-methyl-1-oxopropyl) - β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one; Clostomicin B1; Dificid; Dificlir; Fidaxomicin; Fidaxomycin; Lipiarmicin; Lipiarmycin; Lipiarmycin A 3; OPT 80; PAR 01; PAR 101; R-Tiacumicin B; Tiacumicin. Grades: Highly Purified. CAS No. 873857-62-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??Cl?O??, Molecular Weight: 1058.04. US Biological Life Sciences.
Worldwide
Fidaxomicin Metabolite OP-1118
Fidaxomicin Metabolite OP-1118. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxo-12-(((2R,3S,4S,5S)-3,4,5-trihydroxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate. CAS No. 1030825-28-5. Molecular Formula: C48H68Cl2O17. Mole Weight: 986.38. Catalog: APB1030825285.
Fidrisertib
ALK2-IN-1 is a activin receptor-like kinase-2 ( ALK2 ) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC 50 of <10 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-782; IPN-60130; ALK2-IN-1. CAS No. 2141955-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117887.
Fiduxosin
Fiduxosin is a potent antagonist of α1-adrenoceptor, with Ki= 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively. Fiduxosin was found to have improved uroselectivity relative to tamsulosin. Synonyms: 3-[4-[(3aR,9bR)-9-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-8-phenyl-1H-pyrazino[1,2]thieno[3,4-b]pyrimidine-2,4-dione; 3-(4-(9-methoxy-1,2,3,3a,4,9b-hexahydro(1)benzopyran(3,4-c)pyrrol-2-yl)butyl)-8-phenylpyrazino(2',3'-4,5)thieno(3,2-d)pyrimidine-2,4(1H,3H)-dione; ABT 980; ABT-980; ABT980; fiduxosin. CAS No. 208993-54-8. Molecular formula: C30H29N5O4S. Mole weight: 555.65.
Fiduxosin hydrochloride
Fiduxosin hydrochloride is an alpha(1)-adrenoceptor antagonist used for the treatment of benign prostatic hyperplasia. Synonyms: 3-[4-[(3aR,9bR)-9-methoxy-3,3a,4,9b-tetrahydro-1H-chromeno[3,4-c]pyrrol-2-yl]butyl]-8-phenyl-1H-pyrazino[1,2]thieno[3,4-b]pyrimidine-2,4-dione;hydrochloride; Fiduxosin hydrochloride; Fiduxosin HCl; 208993-54-8 (Fiduxosin) ; 208992-74-9 ( Fiduxosin Hydrochlride). Grades: >98%. CAS No. 208992-74-9. Molecular formula: C30H29N5O4S.HCl. Mole weight: 592.11.
Figitumumab
Figitumumab (CP-751871) is a potent and fully human monoclonal anti - insulin-like growth factor 1 receptor ( IGF1R ) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC 50 of 1.8 nM [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CP-751871. CAS No. 943453-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99197.
Figitumumab
Figitumumab is a monoclonal antibody that targets the insulin-like growth factor type I receptor (IGF1R). Figitumumab binds to IGF1R, resulting in a reduction in receptor expression on tumor cells that express IGF1R and inhibition of tumor growth. Synonyms: CP-751871. CAS No. 943453-46-1.
Fig P.E. 10:1
Fig P.E. 10:1.
CA, FL & NJ
FIIN-1
FIIN-1 is a potent, irreversible and selective FGFR inhibitor with IC50s of 9.2, 6.2, 11.9 and 189 nM against FGFR1/2/3/4, respectively. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8, 6.9, 5.4, 120 nM and 32, 120 nM, respectively. Synonyms: FGFR irreversible inhibitor-1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide. Grades: ≥95%. CAS No. 1256152-35-8. Molecular formula: C32H39Cl2N7O4. Mole weight: 656.60.
FIIN 1 hydrochloride
FIIN 1 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1256152-35-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
FIIN-2
FIIN-2 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547. Synonyms: FIIN2; FIIN 2; FIIN-2. Grades: 98%. CAS No. 1633044-56-0. Molecular formula: C35H38N8O4. Mole weight: 634.73.
FIIN-3
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor. FIIN-3 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547. Synonyms: FIIN3; FIIN 3; FIIN-3. Grades: 98%. CAS No. 1637735-84-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61.
Filaminast
Filaminast is a Type 4 cyclic nucleotide phosphodiesterase inhibitor. It is an analog of rolipram which served as a prototype molecule for several development efforts. In Oct 1999, phase II clinical trials for Asthma in European Union was discontinued. Uses: Asthma. Synonyms: UNII-CDD69JC61J; Way-pda-641; WAY-PDA 641; WAY-PDA-641; CDD69JC61J; SCHEMBL73843; 1-(3-(Cyclopentyloxy)-4-methoxyphenyl)ethanone-(E)-O-(aminocarbonyl)oxime. Grades: 98%. CAS No. 141184-34-1. Molecular formula: C15H20N2O4. Mole weight: 292.33.
Filanesib
Filanesib, also known as ARRY-520, is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. KSP inhibitor ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Synonyms: ARRY-520; ARRY 520; ARRY520. Grades: 0.98. CAS No. 885060-09-3. Molecular formula: C20H22F2N4O2S. Mole weight: 420.479.
Filanesib
Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein ( KSP ) inhibitor, with an IC 50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARRY-520. CAS No. 885060-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15187.
Filapixant
Filapixant is a purinoreceptor antagonist extracted from patent WO2016091776A1, example 348. Filapixant is the active reference substance of Eliapixant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1902607. CAS No. 1948232-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109173.
Filbertone
Filbertone. CAS No. 81925-81-7. FEMA No. 3761. Kosher: Y. VIGON Item # 502978. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Filgotinib
Filgotinib (GLPG0634) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634. CAS No. 1206161-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300.
Filgotinib
Filgotinib is a potent and selective JAK1 inhibitor exhibiting 30-fold selectivity over JAK2. It was shown to inhibit Th1 and Th2 differentiation and to a lesser extent the differentiation of Th17 cells in vitro. Filgotinib has the potential for the treatment of rheumatoid arthritis and possibly other immune-inflammatory diseases. Synonyms: GLPG0634; GLPG-0634; N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide. Grades: >98%. CAS No. 1206161-97-8. Molecular formula: C21H23N5O3S. Mole weight: 425.507.
Filgotinib maleate
Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib maleate can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values ??of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib maleate also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib maleate can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634 maleate. CAS No. 1802998-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300A.
Filipin complex
Filipin are a mixture of polyene macrolide antibiotics produced by Streptomyces filipinensis and Str. durhamensis. Four components I-IV are separated. Grades: >95% by HPLC. CAS No. 11078-21-0. Molecular formula: C35H58O11 (for Flipin III). Mole weight: 654.8.
Filipin II
Filipin II is a polyene macrolide antibiotic produced by Streptomyces filipinensis and Str. durhamensis. It has anti-fungal activity and has the effect of inhibiting Mycoplasma Lebsiella. It also has an effect on the diseases caused by Aspergillus penicillium, stalk mold and other crops such as peas and tomatoes. Grades: >95% by HPLC. CAS No. 38620-77-8. Molecular formula: C35H58O10. Mole weight: 638.83.
Filipin Iii
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 16,20,22,24-Octacosapentenoic Acid. Product Category: Inhibitors. Appearance: White or light yellow solid. CAS No. 480-49-9. Molecular formula: C35H58O11. Mole weight: 654.83. Purity: 0.98. IUPACName: (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one. Canonical SMILES: CCCCC[C@H](C1[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@H](C[C@@H](/C(=C\\C=C\\C=C\\C=C\\C=C\\[C@@H]([C@H](OC1=O)C)O)/C)O)O)O)O)O)O)O)O. Product ID: ACM480499. Alfa Chemistry ISO 9001:2015 Certified.
Filipin III
Filipin III is a polyene macrolide antibiotic produced by Streptomyces filipinensis and Str. durhamensis. It has anti-fungal activity and has the effect of inhibiting Mycoplasma Lebsiella. It also has an effect on the diseases caused by Aspergillus penicillium, stalk mold and other crops such as peas and tomatoes. Synonyms: 14-Deoxylagosin. Grades: >98%. CAS No. 480-49-9. Molecular formula: C35H58O11. Mole weight: 654.83.
Filipin III
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis , S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-49-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6718.
Filipin III (Filimirasin, Filmirisin)
Filipin III (Filimirasin, Filmirisin). Group: Biochemicals. Alternative Names: (17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one. Grades: Purified. CAS No. 480-49-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C35 H58 O11 , Molecular Weight: 654.8. US Biological Life Sciences.
Worldwide
Filixic acid ABA
Botanical Source: Group: Biochemicals. Alternative Names: Trisalbaspidin ABA. Grades: Plant Grade. CAS No. 38226-84-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Filled PTFE Article
Filled PTFE Article. Group: Polymers.
Film Coatings
Film Coatings. Product ID: PE-0191. Category: Coating Systems Excipients. Product Keywords: Pharmaceutical Excipients; Coating Systems Excipients; Film Coatings; PE-0191. Standard: ChP, USP, BP, EP, JP. Grade: Pharmaceutical grade.
Films
Films. Group: Polymers.
Filociclovir
Filociclovir is a broad-spectrum anti-herpesvirus compound with good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8, with EC50 values ranging from 0.7 μM to 8 μM. Uses: Filociclovir is antiviral drug candidate and is used for the treatment of cytomegalovirus infection. Synonyms: Cyclopropavir; ZSM-I-62; MBX-400; 2-Amino-9-[ (Z) -[2, 2-bis (hydroxymethyl) cyclopropylidene]methyl]-3H-purin-6-one; (Z) -2-amino-9- ( (2, 2-bis (hydroxymethyl) cyclopropylidene) methyl) -1, 9-dihydro-6H-purin-6-one; (Z) -9- ( (2, 2-bis- (Hydroxymethyl) cyclopropylidene) methyl) guanine; (Z) -2-amino-9- ( (2, 2-bis (hydroxymethyl) cyclopropylidene) methyl) -1H-purin-6 (9H) -one. Grades: 98%. CAS No. 632325-71-4. Molecular formula: C11H13N5O3. Mole weight: 263.26.
Filorexant
Filorexant, a selective reversible and orally bioavaliable antagonist of OX(1)R receptor and OX(2)R receptor, could probably be an effective compound in the treatment of insomnia. It is still under the Phase II trial by Merck. Binding Ki: less than 3 nM. Uses: Filorexant, a selective reversible and orally bioavaliable antagonist of ox(1)r receptor and ox(2)r receptor, could probably be an effective compound in the treatment of insomnia. Synonyms: FILOREXANT; MK-6096; UNII-E6BTT8VA5Z; MK6096; MK 6096. Grades: 98%. CAS No. 1088991-73-4. Molecular formula: C24H25FN4O2. Mole weight: 420.48.
Fimaporfin
Fimaporfin, a potent chlorin-based photosensitizer, is consisted of a mixture of three isomers A, B and C (25%,50%,25%). Fimaporfin has been developed by di-imide reduction of disulfonated tetraphenyl porphine (TPPS(2a)). The synthesized TPCS(2a) contains 3 isomers as shown by HPLC with low inter-batch variation with respect to isomer formation, less than 0.5% (w/w) of the starting material TPPS(2a) and absorbs light at 652nm. TPCS(2a) was found to be a clinically suitable PCI photosensitizer for photochemical activation of molecules that do not readily penetrate the cellular plasma membrane. Synonyms: Benzenesulfonic acid, 4,4'-[7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21H,23H-porphine-5,20(or 5,10)-diyl]bis-; 4,4'-[7,8(or 17,18)-Dihydro-10,15(or 15,20)-diphenyl-21H,23H-porphine-5,20(or 5,10)-diyl]bis[benzenesulfonic acid]. CAS No. 1443547-43-0. Molecular formula: C132H96N12O18S6. Mole weight: 2330.63.
Fimasartan
Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BR-A-657. CAS No. 247257-48-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0780.
Fimasartan
Fimasartan is an angiotensin II receptor blocker (ARB) with selectivity for angiotensin II receptor type 1. Fimasartan is approved in South Korea for the treatment of patients with hypertension and heart failure. Synonyms: 2-[2-butyl-4-methyl-6-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrimidin-5-yl]-N,N-dimethylethanethioamideBR-A657; BR A657; BRA657; BRA 657; Fimasartan. brand name: Kanarb. Grades: >95%. CAS No. 247257-48-3. Molecular formula: C27H31N7OS. Mole weight: 501.6.
Fimasartan Impurity 1
An impurity of Fimasartan. Fimasartan is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Synonyms: 2-(2-Butyl-4-methyl-6-oxo-1-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1,6-dihydro-5-pyrimidinyl)-N,N-dimethylethanethioamide. Grades: > 95%. Molecular formula: C28H33N7OS. Mole weight: 515.69.
Fimasartan Impurity 2
An impurity of Fimasartan. Fimasartan is a non-peptide angiotensin II receptor antagonist used for the treatment of hypertension and heart failure. Synonyms: 2-butyl-1,?6-dihydro-N,?N,?4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)?-1H-tetrazol-5-yl]?[1,?1'-biphenyl]?-4-yl]?methyl]?-5-Pyrimidineethanethio?amide. Grades: > 95%. CAS No. 1361024-52-3. Molecular formula: C46H45N7OS. Mole weight: 743.98.
Fimasartan Impurity A
Fimasartan Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide. CAS No. 1315478-13-7. Molecular Formula: C13H21N3O2. Mole Weight: 251.32. Catalog: APB1315478137.
Fimasartan Impurity C
Fimasartan Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1361024-52-3. Molecular Formula: C46H45N7OS. Mole Weight: 743.97. Catalog: APB1361024523.
Fimasartan Impurity D
Fimasartan Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-butyl-4-methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide. CAS No. 503155-67-7. Molecular Formula: C46H45N7O2. Mole Weight: 727.9. Catalog: APB503155677.
Fimasartan Impurity E
Fimasartan Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide. CAS No. 178554-19-3. Molecular Formula: C27H31N7O2. Mole Weight: 485.58. Catalog: APB178554193.
Fimasartan Impurity F
Fimasartan Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-butyl-4-methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1,6-dihydropyrimidin-5-yl)-N,N-dimethylethanethioamide. Molecular Formula: C46H45N7OS. Mole Weight: 743.96. Catalog: APB06063.
Fimasartan Impurity H
Fimasartan Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-butyl-4-methyl-6-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methoxy)pyrimidin-5-yl)-N,N-dimethylacetamide. Molecular Formula: C46H45N7O2. Mole Weight: 727.9. Catalog: APB06064.
Fimasartan Impurity I
Fimasartan Impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-butyl-4-methyl-1-((2'-(1-methyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-6-oxo-1,6-dihydropyrimidin-5-yl)-N,N-dimethylethanethioamide compound with 2-(2-butyl-4-methyl-1-((2'-(2-methyl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-6-oxo-1,6-di. Molecular Formula: C56H66N14O2S2. Mole Weight: 1031.35. Catalog: APB06062.
Fimasartan Impurity L
Fimasartan Impurity L. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: triphenylmethanol. CAS No. 76-84-6. Molecular Formula: C19H16O. Mole Weight: 260.33. Catalog: APB76846.
Fimasartan Impurity M
Fimasartan Impurity M. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (methoxymethanetriyl)tribenzene. CAS No. 596-31-6. Molecular Formula: C20H18O. Mole Weight: 274.36. Catalog: APB596316.
Fimasartan Impurity N
Fimasartan Impurity N. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C28H33N7OS. Mole Weight: 515.68. Catalog: APB08039.
Fimepinostat
Fimepinostat (CUDC-907) potently inhibits class I PI3K s as well as classes I and II HDAC enzymes with an IC 50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CUDC-907. CAS No. 1339928-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13522.
FIN56 is a specific inducer of ferroptosis and causes the loss of GPX4 activity in cell lysates. Synonyms: FIN56; FIN-56; FIN 56. 2-N,7-N-dicyclohexyl-9-hydroxyiminofluorene-2,7-disulfonamide; s8254. CAS No. 1083162-61-1. Molecular formula: C25H31N3O5S2. Mole weight: 517.66.
Finafloxacin
Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Uses: Scientific research. Group: Signaling pathways. CAS No. 209342-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13451.
Finafloxacin hydrochloride
Finafloxacin hydrochloride. Group: Biochemicals. Alternative Names: 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride. Grades: Highly Purified. CAS No. 209342-41-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H20ClFN4O4. US Biological Life Sciences.
Worldwide
Finasteride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H36N2O2. CAS No. 98319-26-7. Prepack ID 62364542-1g. Molecular Weight 372.54. See USA prepack pricing.
Finasteride
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H36N2O2. CAS No. 98319-26-7. Prepack ID 62364542-5g. Molecular Weight 372.54. See USA prepack pricing.
Finasteride
Finasteride is a basic drug for the treatment of prostatic hyperplasia and prostatitis in China. It is a synthetic 4-nitrosteric hormone compound and a resistant hormone drug. It can selectively inhibit 5α - reductase, inhibit the process of transforming testosterone into 5α - dihydrotestosterone (DHT), and reduce the level of androgen Chemicalbook in prostate cells. Serum prostate-specific antigen decreased, enlarged prostate volume decreased, urine flow rate increased, thereby reducing the symptoms of patients, to achieve the purpose of treating prostate hyperplasia. The action of the drug is characterized by the selective blocking of androgen stimulation of the prostate gland, but it rarely affects the sexual function of men. CAS No. 98319-26-7. Product ID: PAP-0090. Molecular formula: C23H36N2O2. Product Keywords: Other Active Pharmaceutical Ingredients; Finasteride; PAP-0090; ; C23H36N2O2; 98319-26-7. Appearance: Solid. Grade: GMP. Color: white to beige. EC Number: 620-534-3. Physical State: solid. Solubility: DMSO: 32 mg/mL, soluble. Storage: room temp. Applications: Finasteride is a specific inhibitor of intracellular enzyme type II 5A-reductase in the process of testosterone metabolism to dihydrotestosterone, which can effectively reduce the dihydrotestosterone in the blood and prostate, that is, by inhibiting the conversion of testosterone into dihydrotestosterone (DHT), reduce the size of the pros
Finasteride
Finasteride (MK-906) is an orally active and competitive 5α-reductase inhibitor, with an IC 50 of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-906. CAS No. 98319-26-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13635.
Finasteride
Finasteride. Group: Biochemicals. Grades: Purified. CAS No. 98319-26-7. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Finasteride
N-tertbutyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide. antifungal for cutaneous infections. CAS No. 98319-26-7. Product ID: 8-04726. Molecular formula: C23H36N2O2. Mole weight: 372.55. Purity: 0.99.
Finasteride
Finasteride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Propecia; Finpecia; Chibro-Proscar; Finasteridum; Finasterida; Finasteride; Finastid; MK-906; Proscar; Prostide; (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Product Category: Steroidal Compounds. Appearance: white to off-white crystalline powder. CAS No. 98319-26-7. Molecular formula: C23H36N2O2. Mole weight: 372.54. Purity: 95%+. IUPACName: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide. Canonical SMILES: CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C. Density: 1.065 g/cm³. Product ID: ACM98319267. Alfa Chemistry ISO 9001:2015 Certified.