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| Product | Description | |
|---|---|---|
| G007-LK | G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. G007-LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. G007-LK was first discovered by Dr. Stefan Krauss's team. Synonyms: G007LK; G007LK; G007 LK. Grade: >98%. CAS No. 1380672-07-0. Molecular formula: C25H16ClN7O3S. Mole weight: 529.96. |  |
| G0507 | G0507 is an inhibitor of Escherichia coli growth and induces the extracytoplasmic E stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria. Synonyms: G 0507. Grade: 98%. CAS No. 1223998-29-5. Molecular formula: C18H15N3O3S. Mole weight: 353.39. | |
| G0-C14 | G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1510653-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152229. |  |
| G-1 | G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 and a potent and selective GPER agonist. It displays no activity at ERα and ERβ at concentrations up to 10 μM. It increases cytosolic Ca2+ and inhibits migration of SKBr3 cells and MCF-7 cel. Synonyms: (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone; rel-1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3aR,4S,5,9bS-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone. Grade: > 95%. CAS No. 881639-98-1. Molecular formula: C21H18BrNO3. Mole weight: 412.29. | |
| G-1 | G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a K i of 11 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 881639-98-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107216. | |
| G12 | G12 (Ras 5-17) is a wild-type Ras peptide consisted of amino acids 5-17 (KLVVVGAGGVGKS). G12 can be used as a control of mutant Ras peptides studies (such V12) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Ras 5-17. CAS No. 162550-82-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2360. | |
| G140 | G140 is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor, with IC50s of 14.0?nM and 442?nM for h-cGAS and m-cGAS, respectively. It has anti-inflammatory activity. Synonyms: 1-(6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)-2-hydroxyethanone; Ethanone, 1-[6,7-dichloro-1,3,4,5-tetrahydro-9-(1-methyl-1H-pyrazol-3-yl)-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxy-; 1-[6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethanone. Grade: ≥98%. CAS No. 2369751-07-3. Molecular formula: C17H16Cl2N4O2. Mole weight: 379.24. | |
| G140 | G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0?nM and 442?nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2369751-07-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133916. | |
| G 1499-2 | It is produced by the strain of Cytophaga johnsonii. G 1499-2 can inhibit the growth of Flavobacterium, Staphylococcus aureus and Bacillus subtilis. Synonyms: Antibiotic G 1499-2; (+)-3-Methyl-2-(pentylidenecyclopropyl)-4(1H)-quinolinone; BRN 1485371. CAS No. 68978-12-1. Molecular formula: C18H21NO. Mole weight: 267.36. | |
| G15 | G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a K i of 20 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1161002-05-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103449. | |
| G150 | G150 is a potent and selective inhibitor of human cyclic GMP-AMP synthase (cGAS) with IC50 of 10.2 nM. CAS No. 2369751-30-2. Molecular formula: C18H16Cl2N4O2. Mole weight: 391.25. | |
| G150 | G150 is a highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with an IC 50 of 10.2 nM. G150 represses dsDNA-triggered interferon expression, and G150 can be used for the research of inflammatory [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2369751-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128583. | |
| G1F Glycan, 2-AA labelled | G1F Glycan, 2-AA labelled, a noteworthy carbohydrate molecule, serves as a potent tool for glycomic analysis. Through its ability to detect glycan biomarkers, it has implicated itself as crucial in analyzing aberrant glycosylation patterns in diseases including cancer. This molecular fingerprint finds broad application in mass spectrometry-based glycomic profiling. By furnishing invaluable insights into the progressive role of glycosylation in disease, researchers can harness the potential of this versatile labelled glycan to enhance diagnostic approaches. | |
| G1F Glycan, 2-AB labelled | G1F Glycan, 2-AB labelled. | |
| G-1 (GPR30 Agonist, AC1MJFYZ, MLS001242405) | G-1 (GPR30 Agonist, AC1MJFYZ, MLS001242405). Group: Biochemicals. Alternative Names: 1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]ethanone. Grades: Highly Purified. CAS No. 881639-98-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C21 H18 BrNO 3 , Molecular Weight: 412.3. US Biological Life Sciences. |  Worldwide |
| G1/S-specific cyclin-D1 (101-109) | G1/S-specific cyclin-D1 (101-109) is a truncated fragment of G1/S-specific cyclin-D1. G1/S-specific cyclin-D1 is a regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Synonyms: B-cell lymphoma 1 protein (101-109); BCL-1 oncogene (101-109); PRAD1 oncogene (101-109). | |
| G1/S-specific cyclin-D1 (198-212) | G1/S-specific cyclin-D1 (198-212) is a truncated fragment of G1/S-specific cyclin-D1. G1/S-specific cyclin-D1 is a regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Synonyms: B-cell lymphoma 1 protein (198-212); BCL-1 oncogene (198-212); PRAD1 oncogene (198-212). | |
| G2201-C | G2201-C is originally isolated from Streptomyces cattleya. It is resistant to Gram-positive bacteria and has a weak anti-Gram-negative activity. Synonyms: Antibiotic G2201-C; G 2201C; BRN 2083813; 5-hydroxy-5-(hydroxymethyl)cyclopent-2-ene-1,4-dione. CAS No. 66655-93-4. Molecular formula: C6H6O4. Mole weight: 142.11. | |
| G244-LM | G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization. Synonyms: 3,5,7,8-tetrahydro-2-[4-[2-(methylsulfonyl)phenyl]-1-piperazinyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one. CAS No. 1563007-08-8. Molecular formula: C18H22N4O3S2. Mole weight: 406.5. | |
| G280-9 | G280-9 is a natural epitope peptide containing 9 amino acids and is also a relevant target for melanoma expression. Synonyms: 95 kDa Melanocyte-Specific Secreted Glycoprotein (256-264) (human, bovine, mouse); Melanocyte Lineage-Specific Antigen GP100 (256-264) (human, bovine, mouse); ME20-M/ME20-S (256-264) (human, bovine, mouse); H-Tyr-Leu-Glu-Pro-Gly-Pro-Val-Thr-Ala-OH; L-tyrosyl-L-leucyl-L-alpha-glutamyl-L-prolyl-glycyl-L-prolyl-L-valyl-L-threonyl-L-alanine; Melanocyte Protein PMEL 17 (256-264) (human, bovine, mouse). Grade: ≥95%. CAS No. 156761-76-1. Molecular formula: C44H67N9O14. Mole weight: 946.05. | |
| G280-9 acetate | G280-9 acetate is a natural epitope peptide containing 9 amino acids and is a relevant target for melanoma expression. It is a common melanoma gp100 epitope that is restricted by MHC-associated HLA-A2. Synonyms: H-Tyr-Leu-Glu-Pro-Gly-Pro-Val-Thr-Ala-OH.CH3CO2H; L-tyrosyl-L-leucyl-L-alpha-glutamyl-L-prolyl-glycyl-L-prolyl-L-valyl-L-threonyl-L-alanine acetic acid. Grade: ≥95%. Molecular formula: C46H71N9O16. Mole weight: 1006.12. | |
| G 28UCM | G 28UCM is a fatty acid synthase inhibitor that potently inhibits the proliferation of breast cancer cell. G 28UCM blocks HER2 signaling, induces apoptosis, and suppresses growth of breast cancer xenografts in mice without causing anorexia. Synonyms: 3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate; 1,3-Bis[(3,4,5-Trihydroxybenzoyl)Oxy]Naphthalene. Grade: ≥98% by HPLC. CAS No. 1094451-90-7. Molecular formula: C24H16O10. Mole weight: 464.38. | |
| G2 Glycan | G2 Glycan. Group: Molecular Biology. Grades: Highly Purified. CAS No. 71496-53-2. Pack Sizes: 1mg. Molecular Formula: C62H104N4O46. US Biological Life Sciences. | Worldwide |
| G3130 | G3130 is a reversible Hsp90 inhibitor with potential anticancer activity. G3130 demonstrated cellular activities (in Her-2 degradation and activation of Hsp70 promoter) consistent with the inhibition of cellular Hsp90 functions. Synonyms: G-3130; G 3130; 4-(4-(1H-imidazol-4-yl)-1H-pyrazol-3-yl)-6-ethylbenzene-1,3-diol. Grade: 98%. CAS No. 848952-37-4. Molecular formula: C14H14N4O2. Mole weight: 270.29. | |
| G3335 | G3335 is a cell-permeable dipeptide that selectively and reversibly antagonizes PPARγ with a Kd value of 8.34 μM. G3335 reversiblyand competitively blocks activation of PPARγ by rosiglitazone. Synonyms: tryptophanyl-glutamic acid; Tryptophyl-Glutamate; L-Trp-L-Glu; L-tryptophyl-L-glutamic acid; N-L-Tryptophyl-L-glutamic acid; (S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-pentanedioic acid. Grade: ≥98%. CAS No. 36099-95-3. Molecular formula: C16H19N3O5. Mole weight: 333.34. | |
| G3335 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| G3335 acetate | G3335 acetate is a cell-permeable dipeptide that selectively and reversibly antagonizes PPARγ with a Kd of 8.34 μM. G3335 reversibly and competitively blocks activation of PPARγ by rosiglitazone. Synonyms: H-Trp-Glu-OH.CH3CO2H; WE acetate; L-tryptophyl-L-glutamic acid acetic acid; Acetic acid, compd. with L-tryptophyl-yl L-Glutamate (1:1). Grade: ≥95%. CAS No. 2760881-52-3. Molecular formula: C18H23N3O7. Mole weight: 393.39. | |
| G36 | G-36 is a cell-permeable nonsteroidal antagonist of the G protein-coupled estrogen receptor (GPER/GPR30), which selectively inhibits estrogen-mediated PI3K activation through GPER, rather than Er&alpha. G-36 also inhibits estrogen-mediated calcium mobilization (IC 50 =112 nM). G-36 is promising for research in the field of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1392487-51-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103450. | |
| G-36 | G-36 is an antagonist of G protein-coupled estrogen receptor (GPER). It selectively inhibits estrogen-mediated activation of PI3-K by GPER and estrogen-mediated calcium mobilization (IC50 = 112 nM). Synonyms: GRB-G36; G-36; G36; G 36. (±)-(3aR,4S,9bS)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline. Grade: ≥99% by HPLC. CAS No. 1392487-51-2. Molecular formula: C22H22BrNO2. Mole weight: 412.33. | |
| G 367 S1 | It is an aminoglycoside antibiotic which has anti-gram-positive and anti-gram-negative activities. Synonyms: 2'-N-Formylsisomycin; G-367 S(1); D-Streptamine, O-6-amino-2,3,4,6-tetradeoxy-2-(formylamino)-alpha-D-glycero-hex-4-enopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-, (SP-4-2)-. CAS No. 76647-54-6. Molecular formula: C20H37N5O8. Mole weight: 475.54. | |
| G3-C12 | G3-C12 is a peptide that can bind to Galectin-3 and has anti-cancer activity. Grade: ≥97% by HPLC. CAS No. 848301-94-0. Molecular formula: C74H115N23O23S2. Mole weight: 1759. | |
| G3-C12 acetate | G3-C12 acetate, a galectin-3 binding peptide with Kd of 88 nM, shows anticancer activity. Molecular formula: C76H119N23O25S2. Mole weight: 1819.03. | |
| G3-C12 TFA | G3-C12 TFA is a galectin-3 binding peptide, with Kd of 88 nM, and has anticancer activity. Synonyms: L-Arginine, L-alanyl-L-asparaginyl-L-threonyl-L-prolyl-L-cysteinylglycyl-L-prolyl-L-tyrosyl-L-threonyl-L-histidyl-L-α-aspartyl-L-cysteinyl-L-prolyl-L-valyl-L-lysyl-, trifluoroacetic acid; H-Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg-OH.TFA. Grade: ≥98%. Molecular formula: C74H115N23O23S2.C2HF3O2. Mole weight: 1873.00. | |
| G3-tCbz | G3-tCbz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-(3',6'-Di-tert-butyl-6-(3,6-di-tert-butyl-9H-carbazol-9-yl)-9H-3,9'-bicarbazol-9-yl)-9-(4-(3',6'-di-tert-butyl-6-(3,6-di-tert-butyl-9H-carbazol-9-yl)-9H-3,9'-bicarbazol-9-yl)phenyl)-3',6'-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)-9H-3,9'-bicarbazole. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1025079-68-8. Molecular formula: C174H172N10. Mole weight: 2403.29 g/mol. Product ID: ACM1025079688. Alfa Chemistry ISO 9001:2015 Certified. |  |
| G-418 | G-418 Inhibitor. Uses: Scientific use. Product Category: T6512. CAS No. 108321-42-2. |  |
| G-418 disulfate | G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Geneticin sulfate; Antibiotic G-418 sulfate. CAS No. 108321-42-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17561. | |
| G 418 disulfate salt | powder, BioReagent, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| G 418 disulfate salt solution | 50 mg/mL in H2O, sterile-filtered, BioReagent, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| G418 Sulfate (Geneticin®) | G418 Sulfate is an aminoglycoside related to Gentamycin, used as a selective agent in bacterial genetics. It is toxic to yeast, bacteria, many plant and mammalian cells, helminths and protozoans. Group: Biochemicals. Alternative Names: O-2-Amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1?4)-O-[3-deoxy-4-C-methyl-3-(methylamino)- β-L-arabinopyranosyl-(1?6)]-2-deoxy-D-streptamine Sulfate (1:2); Antibiotic G 418 Sulfate; G418 Sulfate. Grades: Molecular Biology Grade. CAS No. 108321-42-2. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C20H40N4O10 2H2SO4, Molecular Weight: 692.71. US Biological Life Sciences. | Worldwide |
| G418 Sulfate (Geneticin®) 50mg/ml Solution, Sterile-filtered | G418 Sulfate is an aminoglycoside related to Gentamycin. It is used as a selective agent in bacterial genetics. It is toxic to yeast, bacteria, many plant and mammalian cells, helminths and protozoans. Group: Biochemicals. Grades: Molecular Biology Grade. CAS No. 108321-42-2. Pack Sizes: 20ml, 5x20ml. US Biological Life Sciences. | Worldwide |
| G43 | G43 is a potent, selective glucosyltransferase inhibitor, with the K d of 3.7μM and 46.9 nM for GtfB and GtfC, respectively. G43 has antibacterial to S. mutans in vitro and in vivo , and can be used for dental caries study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 690693-02-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155715. | |
| g-4-Aminobutyric acid 99+% | g-4-Aminobutyric acid 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences. | Worldwide |
| G-52 | G-52 is originally isolated from Micromonospora zionesis. It has a wide antibacterial spectrum and is effective against the infection of Escherichia coli, Pseudomonas and Staphylococcus in mice. Synonyms: Antibiotic G-52; Sch-17726; BRN 1334233; 4,6-diamino-3-({3-amino-6-[(methylamino)methyl]-3,4-dihydro-2H-pyran-2-yl}oxy)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)pentopyranoside. CAS No. 51909-61-6. Molecular formula: C20H39N5O7. Mole weight: 461.55. | |
| G-5555 | G-5555 is a selective PAK1 Inhibitor (Ki=3.7 nM) with low clearance (CLp = 3.4 mL/min/kg) and high oral bioavailability (F = 72%). IC50: PAK2= 11 nM, SIK2= 9 mM, KHS1= 10 mM. Synonyms: G - 5555; G 5555; G5555; 8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one59T8-(((2r,5r)-5-amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7. CAS No. 1648863-90-4. Molecular formula: C25H25ClN6O3. Mole weight: 492.96. | |
| G-5555 | G-5555 is a potent p21-activated kinase 1 (PAK1) inhibitor with Kis of 3.7 nM and 11 nM for PAK1 and PAK2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1648863-90-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-19635. | |
| G-5555 hydrochloride | G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2319590-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-19635A. | |
| G-5555 hydrochloride | G-5555 hydrochloride is the hydrochloride salt of G-5555 which is a potent and selective p21-activated kinase 1 (PAK1) inhibitor (Ki = 3.7 nM). G-5555 was potent, showing good activity in the pMEK cellular assay, had improved permeability, and importantly, displayed low hERG channel activity (<50% inhibition at 10 μM). Synonyms: 8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one; hydrochloride; G-5555 (hydrochloride); G 5555 (hydrochloride); G5555 (hydrochloride). Molecular formula: C25H26Cl2N6O3. Mole weight: 529.42. | |
| G5-7 | G5-7 is an orally active and allosteric JAK2 inhibitor. G5-7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5-7 has the potential for glioma study. Synonyms: tert-Butyl 3,5-bis(2-fluorobenzylidene)-4-oxopiperidine-1-carboxylate; 939681-36-4; starbld0009706. Grade: 99%. CAS No. 939681-36-4. Molecular formula: C22H19F2NO3. Mole weight: 383.39. | |
| G 573 | G 573 is used as an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor and an antineoplastic agent. Synonyms: Furo[3,2-c]pyridine-2-carboxamide, 7-fluoro-3-[(2-fluoro-4-iodophenyl)amino]-N-[(2S)-2-hydroxypropoxy]-; 7-Fluoro-3-[(2-fluoro-4-iodophenyl)amino]-N-[(2S)-2-hydroxypropoxy]furo[3,2-c]pyridine-2-carboxamide; 7-Fluoro-3-[(2-fluoro-4-iodophenyl)amino]furo[3,2-c]pyridine-2-carboxylic acid N-[((S)-2-hydroxypropyl)oxy]amide; G-573; G573. Grade: 95%. CAS No. 1009333-44-1. Molecular formula: C17H14F2IN3O4. Mole weight: 489.21. | |
| G-573 | G-573 is an allosteric inhibitor of MEK that is both potent and selective. The IC(50) value for pERK inhibition in HCT116 tumours by G-573 was estimated to be 0.406? μM. The IC(50) values for tumour growth inhibition in HCT116 and H2122 were estimated to be 3.43 and 2.56?μM, respectively. ED(50) estimates in HCT116 and H2122 mouse xenograft models were estimated to be ~4.6 and 1.9?mg/kg/day, respectively. Synonyms: G 573; G573; 2-(3-chlorophenyl)benzimidazole; OTAVA-BB; 1H-Benzimidazole, 2-(3-chlorophenyl)-; Benzimidazole, 2-(m-chlorophenyl)-. 2-(3-Chlorophenyl)-1H-1,3-benzodiazole; 2-(3'-Chlorophenyl)benzimidazole; 2-(m-Chlorophenyl)benzimidazole. Grade: ≥95%. CAS No. 22868-35-5. Molecular formula: C13H9ClN2. Mole weight: 228.68. | |
| g-[6-Aminohexyl]-ATP (Biotin) | Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: g-[6-Aminohexyl]-adenosine-5-triphosphate (Biotin), Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 50ul. US Biological Life Sciences. | Worldwide |
| g-[6-Aminohexyl]-GTP (Biotin) | Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: g-[6-Aminohexyl]-guanosine-5-triphosphate (Biotin), Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 50ul. US Biological Life Sciences. | Worldwide |
| g-[(6-Aminohexyl)-imido]-ATP (Biotin) | Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: g-[(6-Aminohexyl)-imido]-adenosine-5-triphosphate (Biotin), Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 50ul. Molecular Formula: C26H44N9O14P3S (free acid), Molecular Weight: 831.66g/mol (free acid). US Biological Life Sciences. | Worldwide |
| G6PD activator AG1 | G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) agonist with an EC50 of 3 ?M. G6PD is an oxidoreductase that catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone and the simultaneous reduction of NAD phosphate (NADP) to reduced NADP (NADPH). G6PD activator AG1 can reduce hemolysis of human erythrocytes[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 421581-52-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123962. | |
| G6PDi-1 | G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC 50 of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2457232-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W107464. | |
| G6PDi-1 | G6PDi-1 is a small molecule inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 depletes NADPH and decreases inflammatory cytokine production. Synonyms: G6PDi-1; 2457232-14-1; 4-((5-Oxo-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-yl)amino)thiophene-2-carbonitrile4-[(5-oxo-6,7,8,9-tetrahydrocyclohepta[d]pyrimidin-2-yl)amino]thiophene-2-carbonitrile; EX-A3990. CAS No. 2457232-14-1. Molecular formula: C14H12N4OS. Mole weight: 284.34. | |
| G7063-2 | G7063-2 is produced by the strain of Streptomyces sp. It has anti-Gram-positive bacteria, negative bacteria and fungi activities. Synonyms: Antibiotic G-7063-2; 2-Amino-3,6-dioxo-4,5-epoxy-1-cyclohexene-1-carboxamide; 4-Amino-7-oxa-bicyclo(4.1.0)hept-3-ene-2,5-dione-3-carboxamide. Molecular formula: C7H6N2O4. Mole weight: 182.13. | |
| G-749 | G-749 Inhibitor. Uses: Scientific use. Product Category: T2620. CAS No. 1457983-28-6. | |
| G-749 | G-749 potently inhibits autophosphorylation of FLT3 with IC50 of ≤8 nM. In leukemia cells, G-749 shows antiproliferative activity by inducing apoptosis. Synonyms: G749; G-749; G 749. Grade: >98%. CAS No. 1457983-28-6. Molecular formula: C25H25BrN6O2. Mole weight: 521.41. | |
| G907 | G907 is a selective antagonist of ATP-binding cassette (ABC) transporter MsbA with anti-microbial activity. G907 inhibits E. coli MsbA with an IC 50 value of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244035-16-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-125176. | |
| GA-017 | GA-017 is a potent and selective LATS1 and LATS2 (large tumor suppressor kinase 1/2) inhibitor, with IC50 values of 4.10 and 3.92 nM, respectively. GA-017 is an activator of cell proliferation. GA-017 promotes YAP/TAZ activation and nuclear translocation. GA-017 promotes cell growth under 3D culture conditions. GA-017 enhances the ex vivo formation of mouse intestinal organoids[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2351906-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147082. | |
| GA11 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GA1-Ganglioside | GA1-Ganglioside is a potent compound used to study Gangliosidosis Type 1, a rare and progressive genetic disorder. Derived from natural sources, this product can replenish the deficient GA1-ganglioside enzyme. Synonyms: Ganglio-N-tetraosylceramide; Ceramide tetrahexoside; GgOse4Cer; asialo-GM1; 1-O-[O-β-D-Galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide; Asialo ganglioside GM1a; Asialo GM1; Asialo GM1 ganglioside; Asialoganglioside GM1; Asialoganglioside GT1b; Ganglioside GA1; Gangliotetraosylceramide; Gg4Cer. CAS No. 71012-19-6. Molecular formula: C62H114N2O23. Mole weight: 1255.6. | |
| GA2-Ganglioside | GA2-Ganglioside, a glycolipid situated on the cell surface, performs a crucial action by boosting communication between neighboring nerve cells in the nervous system. Its medicinal potency in treating diverse neurological illnesses, including Parkinson's and Alzheimer's, has been researched extensively. Furthermore, it seems GA2-Ganglioside promotes the functionality and longevity of dopaminergic neurons, making it a highly sought-after therapy for Parkinson's. Synonyms: Asialoganglioside-GM2; Gangliotriosyl ceramide; GgOse3Cer; b-GalNAc-(1→4)-b-Gal-(1→4)-b-Glc-(1→1)-Cer; Ceramide, 1-O-[O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-; 1-O-[O-2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide; Asialo Gm2; Asialoganglioside GM2; Cg3Cer; Ganglio-N-triaosylceramide; Ganglioside A2; Ganglioside GA2; Ganglioside Gg3; Gangliotriaosylceramide; Gangliotriosylceramide; Gg3Cer; Glycolipid GA2; Glycosphingolipid GA2; Tay-Sachs globoside. CAS No. 35960-33-9. Molecular formula: C56H104N2O18. Mole weight: 1093.43. | |
| GA32 | GA32 (compound 58r) is potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC 50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide (HY-70002) resistance castration-resistant prostate cancer both in vitro and in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1386811-71-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-163340. | |
| GAA. (Glacial Acetic Acid 99%) | GAA. (Glacial Acetic Acid 99%). Uses: Chemical industry: raw material in the production of various chemical compounds, such as ethyl acetate, vinyl acetate, cellulose acetate and other esters. -food and beverage industry: used as a food additive in the food and beverage industry. -textile industry: used in the textile dyeing and finishing process. helps fix dyes in textile fibers and improve color fastness. - cleaning and disinfection industry: cleaning and disinfection products due to their antimicrobial properties. it can be used to remove stains, descale surfaces and disinfect areas. ?. Purity: Industrial. CAS No. 64-19-7. Pack Sizes: BULK. Product ID: UN2789. |  |
| GABAA receptor agent 2 TFA | GABAA receptor agent 2 TFA is a potent and high-affinity antagonist of GABAA receptor with an IC50 of 24 nM for human α1β2γ2 GABAA-expressing tsA201 cells and a Ki of 28 nM for rat GABAA receptors. It has no inhibitory activity against four human GABA transporters (hGAT-1, hBGT-1, hGAT-2, and hGAT-3). Synonyms: PHP 501 trifluoroacetate; 4-(5-[1,1'-Biphenyl]-3-yl-1-hydroxy-1H-pyrazol-4-yl)piperidine trifluoroacetate; 5-([1,1'-Biphenyl]-3-yl)-4-(piperidin-4-yl)-1H-pyrazol-1-ol 2,2,2-trifluoroacetate; 5-(3-Biphenylyl)-4-(4-piperidinyl)-1H-pyrazol-1-ol trifluoroacetate (1:1). Grade: ≥95%. CAS No. 1781880-44-1. Molecular formula: C22H22F3N3O3. Mole weight: 433.42. | |
| GABAB receptor antagonist 1 | GABAB receptor antagonist 1, a selective and negative allosteric modulator of GABAB (γ-aminobutyric acid) receptors, reduces GABA-induced IP3 (inositol triphosphate) production with an IC50 of 37.9 μM. Synonyms: 4-[4-Hydroxy-3,5-bis(2-methyl-2-propanyl)phenyl]-2-oxo-3-butenoic acid; 3-Butenoic acid, 4-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-oxo-. Grade: ≥95%. CAS No. 797-17-1. Molecular formula: C18H24O4. Mole weight: 304.38. | |
| Gabaculine | It is produced by the strain of Streptomyces toyocaensis. Gabaculine inhibits GABA aminotransferase by binding to the enzyme to form Schiff group firstly, and then aromatizing to form m-aminobenzoic acid derivatives. Synonyms: 3-Amino-2,3-dihydrobenzoic acid; DL-Gabaculine; 5-Amino-1,3-cyclohexadienylcarboxylic acid; 3-Amino-4,6-cyclohexadienecarboxylic acid. CAS No. 59556-18-2. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| GABA (Gamma-aminobutyrIc acid, γ-Aminobutyric Acid) | An important inhibitory neurotransmitter. Foods that contain γ-aminobutyric acid (GABA) can have an immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity. Acts as a GABAA and GABAB receptor agonist. Group: Biochemicals. Alternative Names: 4-Aminobutanoic Αcid; 3-Carboxypropylamine; 4-Aminobutyric Acid; Aminalon; GABA; Gaballon; Gamarex; Gammalon; Gammalone; Gammar; Gammasol; Mielogen; Mielomade; NSC 27418; NSC 32044; NSC 45460; NSC 51295; Oryza GABA Extract HC 90; Pharma-GABA 20S; Pharmagaba; Pharmagaba 20; Pharmagaba 20D; Piperidic acid; Piperidinic acid; γ-Aminobutanoic acid; γ-Aminobutyric Acid. Grades: Reagent Grade. CAS No. 56-12-2. Pack Sizes: 100g, 500g, 1Kg. US Biological Life Sciences. | Worldwide |
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