A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Gosogliptin is a dipeptidyl peptidase IV (DPP-IV) inhibitor. But no development was reported about Phase-II for Type-2 diabetes mellitus. Uses: Type 2 diabetes mellitus. Synonyms: UNII-GI718UO477; PF-00734200; PF 00734200; PF00734200; PF-734200; PF 734200; PF734200; CHEMBL515387;(3,3-difluoropyrrolidin-1-yl)-[(2S,4S)-4-(4-pyrimidin-2-ylpiperazin-1-yl)pyrrolidin-2-yl]methanone;89490-47-1(dihydrochloride). Grades: 98%. CAS No. 869490-23-3. Molecular formula: C17H24F2N6O. Mole weight: 366.42.
Gosorelin Acetate
Gosorelin Acetate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 145781-92-6. Molecular Formula: C61H88N18O16. Mole Weight: 1329.46. Catalog: APB145781926.
Gossypetin
Gossypetin is a hexahydroxylated flavonoid and is a potent mitogen-activated protein kinase kinase (MKK)3 and MKK6 inhibitor with strongly attenuates the MKK3/6-p38 signaling pathway, has various pharmacological activities, including antioxidant, antibacterial and anticancer activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 489-35-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119917.
Gossypetin
Gossypetin. Group: Biochemicals. Grades: Highly Purified. CAS No. 489-35-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C15H10O8. US Biological Life Sciences.
Worldwide
Gossypetin
Gossypetin is a flavonol compound isolated from the flowers and the calyx of Hibiscus sabdariffa (roselle). It has been shown to exhibit antibacterial activity and act as a TrkB antagonist. Synonyms: Articulatidin; Equisporol; 3,5,7,8,3',4'-Hexahydroxyflavone; 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxychromen-4-one. CAS No. 489-35-0. Molecular formula: C15H10O8. Mole weight: 318.237.
Gossypin
50mg Pack Size. Group: Biochemicals, Organics, Research Organics & Inorganics. Formula: C21H20O13. CAS No. 652-78-8. Prepack ID 34845597-50mg. Molecular Weight 480.4. See USA prepack pricing.
Gossypin
Gossypin is a flavone isolated from Hibiscus vitifolius and has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits RANKL-induced osteoclastogenesis both in mouse primary bone marrow cells and RAW 264.7 cells in vitro [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 652-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-125911.
Gossypin
Gossypin is a pentahydroxyflavone glucoside isolated from Hibiscus vitifolius. Gossypin exhibits antioxidant, antiinflammatory, anticancer and antidiabetic activities. Synonyms: 3,3,4,5,7,8-Hexahydroxy flavone-8-glucoside; Gossypetin 8-glucoside. CAS No. 652-78-8. Molecular formula: C21H20O13. Mole weight: 480.38.
Gossypol
Gossypol is an orally-active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cell cycle arrest at the G0/G1 phase, thereby inhibiting DNA replication and inducing apoptosis. This agent also inhibits cell-signaling enzymes, resulting in inhibition of cell growth, and may act as a male contraceptive. Uses: Antimicrobial. Synonyms: 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde. Grades: > 98 %. CAS No. 303-45-7. Molecular formula: C30H30O8. Mole weight: 518.55.
Gossypol
Gossypol binds to Bcl-xL protein and Bcl-2 protein with K i s of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: BL 193. CAS No. 303-45-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13407.
Gossypol
100mg Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Stains & Indicators. Formula: C30H30O8. CAS No. 303-45-7. Prepack ID 41989683-100mg. Molecular Weight 518.6. See USA prepack pricing.
Gossypol
Gossypol. Group: Biochemicals. Alternative Names: 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; (±)-Gossypol; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl-2,2'-binaphthyl-8,8'-dialdehyde; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-diisopropyl[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-2,2'-binaphthalene-8,8'-dicarboxaldehyde; 1,6,7,1',6',7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthalenyl-8,8'-dicarboxaldehyde; 2,2'-Bis[1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthyl]; 2,2'-Bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthyl]; BL 193; Gossypol; NSC 56817; NSC 624336; No Fertil; Pogosin; Tash 1. Grades: Highly Purified. CAS No. 303-45-7. Pack Sizes: 100ug. Molecular Formula: C30H30O8, Molecular Weight: 518.549999999999. US Biological Life Sciences.
Worldwide
Gossypol acetate
Gossypol acetate - Product ID: NST-10-197. Category: Polyphenols. Purity: 98%. Test method: HPLC. CAS No. 12542-36-8. Pack Sizes: 1g, 2g, 5g, 10g. Appearance: White to yellow Powder. Molecular formula: C32H34O10. Mole weight: 578.61. Storage: +2 +8 °C.
Gossypol (acetic acid)
Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein with K i s of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Gossypol-acetic acid; BL-193 (acetic acid). CAS No. 12542-36-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17510.
Gossypol Acetic Acid is a phenol compound from plants of the Gossypium genus, Malvaceae. It binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. It exhibits antiviral activity at low concentration. Uses: Spermatocidal agents. Synonyms: Gossypol acetate; Acetate gossypol. Grades: 98 % by HPLC. CAS No. 12542-36-8. Molecular formula: C32H34O10. Mole weight: 578.61.
Gossypolone
Gossypolone is an RNA-binding protein Musashi-1 inhibitor with a K i of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4547-72-2. Pack Sizes: 1 mg. Product ID: HY-119734.
Gosuranemab
Gosuranemab (BMS-986168) is a humanised IgG4 anti- tau monoclonal antibody. Gosuranemab binds to human N-terminal tau residues 15-22. Gosuranemab has the potential for the research of alzheimers disease (AD) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986168; IPN007; BIIB092. CAS No. 1788032-39-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99648.
Gotistobart
Gotistobart (ONC-392) is a humanized anti-CTLA-4 antibody that confers immunotherapeutic effect by selective depletion of regulatory T cells (Treg) in the tumor microenvironment [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ONC-392; BNT 316. CAS No. 2226344-78-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990042.
Gotu Kola Extract
Extract obtained from the leaves of the Gotu Kola plant (Centella Asiatica) dissolved in a base of glycerin and water. Gotu Kola contains pentacyclic triterpenoids, including asiaticoside, brahmoside, asiatic acid, and brahmic acid (madecassic acid) and is used in products for irritated and sensitive skin. Uses: Serums, creams & lotions, skin cleansers, sun- and after-sun care, sunscreens, face & hair masks. Group: Skin actives. CAS No. 56-81-5 / 7732-18-5 / 84776-24-9 / 84696-21-9 / 122-99-6. Appearance: Light to medium amber liquid, characteristic odor. Catalog: CI-SC-0682.
Gotu Kola Extract (Ratio)
Gotu Kola Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gotu Kola Extract (Ratio). Cat No: EXTW-069.
Gotu Kola Extract (Standard)
Centella asiatica, commonly known as centella and gotu kola, is a small, herbaceous, annual plant of the family Mackinlayaceae or subfamily Mackinlayoideae of family Apiaceae, and is native to wetlands in Asia.[2][3] It is used as a medicinal herb in Ayurvedic medicine, traditional African medicine, and traditional Chinese medicine. It is also known as the Asiatic pennywort or Indian pennywort in English, among various other names in other languages. Applications: As a member of the parsley family, gotu kola has long been used in traditional chinese medicine and ayurveda (the traditional medicine of india) to heal skin conditions such as psoriasis, fight mental fatigue, and tre...ells and tissues participating in the process of healing, particularly connective tissues. one of its constituents, asiaticoside, works to stimulate skin repair and strengthen skin, hair, nails and connective tissue (kartnig, 1988).now sold as an herbal supplement, gotu kola extract has yet to be extensively researched and its application is being expanded accordingly. Group: Others. CAS No. Asiaticoside: 16830-15-2Madecassoside: 34540-22-2. Purity: 10.0~20.0% Triterpenes HPLC. Mole weight: Asiaticoside: 959.12Madecassoside: 975.12. Gotu Kola Extract (Standard); Asiaticoside: 16830-15-2Madecassoside: 34540-22-2; Asiaticoside: C48H78O19Madecassoside: C48H78O20. Cat No: EXTW-005.
Gotu Kola P.E. 10% Asiaticosides HPLC
Gotu Kola P.E. 10% Asiaticosides HPLC.
CA, FL & NJ
Gotu Kola Powder
Gotu Kola Powder.
CA, FL & NJ
Gouache mixing bottle
This packing material is easy to carry as a travel suit. Product ID: PM-072. Category: Double cavity mixed one bottle. Product Keywords: Cosmetic Plastic Packaging; Gouache mixing bottle; PM-072; Double cavity mixed one bottle;. Administration route: Total height: 105mm. Straight diameter: 25mm. Cover material: AS/PCTG. Pump head material: PP. Bottle material: AS/PCTG.
Gougerotin
It is produced by the strain of Streptomyces gougerotii 21544. It has weak activity against gram-positive bacteria, negative bacteria and mycobacterium, and can inhibit Newcastle disease virus, vaccinia virus, pseudorabies virus and western equine encephalomyelitis virus. Synonyms: Antibiotic 21544; Asteromycin; 1-(4-Deoxy-4-(sarcosyl-D-seryl)amino-beta-D-glucopyranuronamide)cytosine; N(4)-Sarcosyl-1-(3'-deoxy-3'-D-serylamido-beta-D-allopyranosyluronamide)cytosine; Glucopyranuronamide, 1- (4-amino-2-oxo-1 (2H) -pyrimidinyl) -1, 4-dideoxy-4- (D-2- (2- (methylamino) acetamido) hydracrylamido) -, beta-D-; Aspiculamycin; Quingfengmycin. CAS No. 2096-42-6. Molecular formula: C16H25N7O8. Mole weight: 443.41.
Govorestat
Govorestat (AT-007) is an orally active brain-penetrant aldose reductase inhibitor with an IC 50 value of 100 pM. Govorestat has the potential for galactose-1-phosphate uridyl transferase deficiency research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-007. CAS No. 2170729-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129586.
g-Oxo-3-pyridinebutyric Acid
g-Oxo-3-pyridinebutyric Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
g-Oxo-3-pyridinebutyric Acid, N-Hydroxysuccinimide Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
GP 1a
GP 1a is a highly selective CB2 receptor inverse agonist (pEC50 = 7.1), which displays approximately 30-fold selectivity for CB2 receptors over CB1 receptors. Synonyms: N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide; 1-(2,4-dichlorophenyl)-6-methyl-N-(1-piperidinyl)-4H-indeno[1,2-c]pyrazole-3-carboxamide. Grades: ≥99% by HPLC. CAS No. 511532-96-0. Molecular formula: C23H22Cl2N4O. Mole weight: 441.35.
GP 2a
GP 2a is a selective CB2 receptor agonist that also dispalys modest agonism at CB1 receptors with Ki values of 7.6 and 900 nM, respectively. Synonyms: N-Cyclohexyl-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide. Grades: ≥99% by HPLC. CAS No. 919077-81-9. Molecular formula: C24H23Cl2N3O. Mole weight: 440.36.
GP2G
GP2G is an extraordinary pharmaceutical, finding applications in studying numerous autoimmune afflictions encompassing rheumatoid arthritand multiple sclerosis. Its mechanism of action entails robust immunosuppression alongside notable anti-inflammatory properties. Synonyms: P1-(5'-Guanosyl)-P2-(5'-guanosyl)-diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C20H26N10O15P2(free acid). Mole weight: 708.43 (free acid).
GP2(Nic)
GP (33-41)
GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus. Synonyms: H-Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys-OH; L-lysyl-L-alanyl-L-valyl-L-tyrosyl-L-asparaginyl-L-phenylalanyl-L-alanyl-L-threonyl-L-cysteine. Grades: ≥95%. CAS No. 161928-86-5. Molecular formula: C46H69N11O13S. Mole weight: 1016.18.
GP3G
GP3G is a kind of diguanosine polyphosphate, could be found in human plasma. Synonyms: G(5')ppp(5')G; P1-(Guanosyl) P3-(5'-(guanosyl))triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C20H27N10O18P3. Mole weight: 788.41.
GP3G (Unmethylated Cap Analog)
GP3G is a kind of diguanosine polyphosphate, could be found in human plasma. Synonyms: G(5')ppp(5')G Cap Analog; Diguanosine triphosphate; Diguanosine-5'-triphosphate; P1-(Guanosyl) P3-(5'-(guanosyl))triphosphate; CAP. Grades: ≥ 95 % by HPLC. CAS No. 6674-45-9. Molecular formula: C20H27N10O18P3. Mole weight: 788.41.
GP4G
GP4G, a naturally occurring compound found in green tea and seaweed, is a multifunctional ingredient commonly employed as a dietary supplement and cosmetic product ingredient. Various investigations indicate its significant role in augmenting skin cell metabolism and safeguarding against ultraviolet radiation-induced harm. Moreover, studies exhibit the potential of GP4G in bolstering brain function and exercise performance. The compound is also a promising candidate in treating afflictions such as Alzheimer's disease and stroke. Synonyms: P1-(5'-Guanosyl)-P4-(5'-guanosyl)-tetraphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C20H28N10O21P4. Mole weight: 868.39.
Gp4U
Gp4U is an innovative and groundbreaking biomedical compound, used for studying diverse malignancies such as breast, lung and colon cancer. Synonyms: P1- (5'- Guanosyl)- P4- (5'- uridyl)- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 79695-25-3. Molecular formula: C19H27N7O22P4 (free acid). Mole weight: 829.4 (free acid).
GP531
GP531 is a novel riboside with similar structural and anti-ischemic properties to the adenosine-regulating agent (ARA) acadesine. Synonyms: 5-amino-1-[(2R,3R,4S,5R)-5-[(benzylamino)methyl]-3,4-dihydroxyoxolan-2-yl]imidazole-4-carboxamide; 5-amino-1-beta-D-(5'-benzylamino-5'-deoxyribofuranosyl)imidazole-4-carboxamide; GP 531; GP-531; GP531. CAS No. 142344-87-4. Molecular formula: C16H21N5O4. Mole weight: 347.37.
Gp 7
Heterocyclic Organic Compound. Alternative Names: GP 7. CAS No. 125670-69-1. Molecular formula: C22H22O8. Mole weight: 414.408. Purity: 0.96. IUPACName: (5R,5aR,8aS,9S)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5-[(1-$l^{1}-oxidanyl-2,2,6,6-tetramethylpiperidin-4-yl)amino]-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one. Catalog: ACM125670691.
GpAp is a synthetic linear dinucleotide not binding to the c-diGMP-I riboswitch. Synonyms: Guanylyl- (3' -≥ 5')- adenosine- 3'- O- phosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 17332-08-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4.
GPBAR-A
GPBAR-A. Group: Biochemicals. Grades: Purified. CAS No. 877052-79-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GPBAR-A
GPBAR-A is a GPBA receptor agonist. GPBAR-A increases GLP-1 secretion from intestinal cultures. Synonyms: GPBAR-A; GPBAR A; GPBARA; 4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one. Grades: ≥98% by HPLC. CAS No. 877052-79-4. Molecular formula: C23H15F7N2O2. Mole weight: 484.37.
GpCp
GpCp is an analogue of GDP and has been found to be hydrolytically stable. Synonyms: GMPCP; Guanosine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 32381-15-0. Molecular formula: C11H14N5Na3O10P2. Mole weight: 507.20.
GpCpp
GpCpp is an analogue of GTP and could be used as a stabilizer in some microtubule cryoelectron microscopy studies. Uses: Antiviral agents. Synonyms: GMPCPP; Guanosine-5'-[(α,β)-methyleno]triphosphate. Grades: ≥ 95 % by HPLC. CAS No. 14997-54-7. Molecular formula: C11H18N5O13P3. Mole weight: 521.21.
GPCR agonist-2
GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC 50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 291528-35-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-47823.
GPCR Compound Library
A unique collection of 1633 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; - Potential to find new GPCR drug candidates by screening against orphan GPCRs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include 5-HT receptor, dopamine receptor, opioid receptor, adrenergic receptor, mGluR, Cannabinoid receptor, ETA-receptor, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1500. Categories: GPCR Compounds Libraries.
GPCR Compound Library Plus
Quantity: well-chosen 338 GPCR targeting compounds with unique structures; - High bioactivity: All compounds with IC50 below 3. 5 μM; - Targets include 21 various GPCR subtypes; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - HNMR/LCMS validated to ensure high purity and quality; - A powerful tool for GPCR drug development and target identification. Uses: Scientific use. Product Category: L1580. Categories: GPCR Compounds Libraries Plus.
A cell-permeable quinolinimine compound that acts as a selective, potent blocker of G-protein coupled receptors (GPCR) that contain a constrained eighth helix (H8). The inhibition is selective and blocks G-protein signaling mediated via Gaq, but not Ga12. A non-orthosteric antagonist of PAR1 (IC50=4uM) that is shown to inhibit PAR1 and CCR-4 induced platelet aggregation without affecting PAR4 mediated aggregation. Shown to inhibit thrombus formation following vascular injury (IC50 ~1mg/kg). Also acts as a potent, non-competitive blocker of a2A-adrenergic receptors (IC50=2.5uM as shown by a decrease in 3H-yohimbine binding). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
GPCR modulator-1
GPCR modulator-1 is a negative allosteric modulator of GLP receptor. GPCR modulator-1 has the potential for type 2 diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1407592-99-7. Pack Sizes: 1 mg. Product ID: HY-124803.
GPDA
GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: GPN; Glycylproline p-nitroanilide tosylate. CAS No. 65096-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16710.
g-pen-g-r-g-D-s-p-c-a
Heterocyclic Organic Compound. Alternative Names: G-PEN-G-R-G-D-S-P-C-A;GLY-PEN-GLY-ARG-GLY-ASP-SER-PRO-CYS-ALA;gly-pen-gly-arg-gly-asp-ser-pro-cys-ala (pen2,cys. CAS No. 111844-17-8. Molecular formula: C35H57N13O14S2. Mole weight: 948.04. Catalog: ACM111844178.
G-PET PETG 3D Printing Filament
G-PET PETG 3D Printing Filament. Group: 3d printing materials.
GPI-15427
GPI-15427 is a potent PARP-1 inhibitor capable of crossing the blood-brain barrier, which can significantly increased the antitumor activity of the methylating agent TMZ against malignant melanoma, glioblastoma multiforme, or lymphoma growing at the CNS site. GPI-15427 acts as a potent inhibitor of the enzyme, being capable of inhibiting the activity of purified PARP-1 at nanomolar concentrations. GPI-15427 induced significant sensitization to radiotherapy, representing a promising new treatment in the management of HNSCC. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: GPI 15427; GPI15427; 10-((4-Methylpiperazin-1-yl)methyl)chromeno(4,3,2-de)phthalazin-3(2H)-one. CAS No. 805242-85-7. Molecular formula: C20H20N4O2. Mole weight: 348.41.
GPi 688
GPi 688 is an allosteric glycogen phosphorylase inhibitor that inhibits glucagon-mediated hyperglycemia in the rat. Synonyms: GPi 688; GPi688; GPi-688; 2-Chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl]-6H-thieno[2,3-b]pyrrole-5-carboxamide. Grades: ≥99% by HPLC. CAS No. 918902-32-6. Molecular formula: C19H18ClN3O4S. Mole weight: 419.88.
GPLGIAGQ
GPLGIAGQ, is an MMP2-cleaved polypeptide that is used as a stimulus-sensitive connector in both liposomes and micelle nanoceroses for targeted therapy of tumors triggered by MMP2. Synonyms: L-Glutamine, glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-; Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln. Grades: ≥97% by HPLC. CAS No. 109053-09-0. Molecular formula: C31H53N9O10. Mole weight: 711.81.
GPNA hydrochloride
GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase ( GGT ). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na + -dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na + -independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67953-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W011391.
GPP 78
GPP 78 is a potent inhibitor of Nicotinamide phosphoribosyltransferase (Nampt) with an IC50 value of 3 nM. Synonyms: CAY10618; NMPRTase Inhibitor; N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-1H-1,2,3-triazole-1-octanamide. Grades: ≥95%. CAS No. 1202580-59-3. Molecular formula: C27H29N5O. Mole weight: 439.6.
GPP 78 hydrochloride
GPP 78 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), which is subsequently converted to NAD+. It was shown to induce autophagy in neuroblastoma cells. Synonyms: GPP 78 hydrochloride; GPP78 hydrochloride; GPP-78 hydrochloride; N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C27H29N5O.HCl. Mole weight: 476.01.
GPP 78 hydrochloride
GPP 78 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GppNH2
GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPN; Guanosine-5'-(β-amino)-diphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C10H16N6O10P2. Mole weight: 442.21.
GppNHp - Tetralithium salt
The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Tetralithium salt; GMPPNHP. Grades: ≥ 95 % by HPLC. CAS No. 64564-03-0. Molecular formula: C10H13N6ONa413P3. Mole weight: 611.13.
GppNHp - Trisodium salt
The trisodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Trisodium salt; GMPPNHP. Grades: ≥ 90 % by HPLC. CAS No. 148892-91-5. Molecular formula: C10H14N6Na3O13P3. Mole weight: 588.14.
A cell-permeable Niacin triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or b-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5uM) and isoproterenol (1uM), respectively, in GPR109b-expressing CHO cells (EC50=400nM) and freshly isolated human adipocytes (EC50 about 1uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 306935-41-1. Pack Sizes: 25mg. US Biological Life Sciences.
A pyrimidine compound that acts as an effective GPR119 agonist (EC50=2.5uM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward B-adrenergic or GLP-1 receptors. Shown to enhance 16.8mM glucose-induced insulin secretion from murine MIN-6 B-cells (mU/20 min=0.44 and 0.22, respectively, with or without 10uM AS1269574) in vitro and improve glucose tolerance in normal mice (100mg/kg; p.o.) without any significant hypoglycemic effect in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 330981-72-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
GPR120-IN-1
GPR120-IN-1, a cell-permeable azaspiroundecanyl acetic acid compound, is an orally available, selective agonist of GPR120 (EC50 = ~0.35 μM) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1). Synonyms: 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid; GPR120 Compound A; MDK77754; MDK-77754; MDK 77754; GPR120 cpdA. CAS No. 1599477-75-4. Molecular formula: C19H23ClF3NO3. Mole weight: 405.84.
GPR120 modulator 1
GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 1; 1050506-75-6; 2-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenoxy]acetic acidAcetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]-GPR120-modulator-1. Grades: >98%. CAS No. 1050506-75-6. Molecular formula: C19H16ClNO4S. Mole weight: 389.85.