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| Product | Description | |
|---|---|---|
| GPCR-Helix 8 Signaling Inhibitor, JF5 (GPCR-H8 Signaling Inhibitor, JF5, 4-Pentyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-imine, HI, 4-Pentyl-1,2,3,4-tetrahydro-9H-cyclopenta[b]quinolin-9-imine, HI) | A cell-permeable quinolinimine compound that acts as a selective, potent blocker of G-protein coupled receptors (GPCR) that contain a constrained eighth helix (H8). The inhibition is selective and blocks G-protein signaling mediated via Gaq, but not Ga12. A non-orthosteric antagonist of PAR1 (IC50=4uM) that is shown to inhibit PAR1 and CCR-4 induced platelet aggregation without affecting PAR4 mediated aggregation. Shown to inhibit thrombus formation following vascular injury (IC50 ~1mg/kg). Also acts as a potent, non-competitive blocker of a2A-adrenergic receptors (IC50=2.5uM as shown by a decrease in 3H-yohimbine binding). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| GPCR modulator-1 | GPCR modulator-1 is a negative allosteric modulator of GLP receptor. GPCR modulator-1 has the potential for type 2 diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1407592-99-7. Pack Sizes: 1 mg. Product ID: HY-124803. |  |
| GPDA | GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: GPN; Glycylproline p-nitroanilide tosylate. CAS No. 65096-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16710. | |
| G-PET PETG 3D Printing Filament | G-PET PETG 3D Printing Filament. Group: 3d printing materials. |  |
| GPI-15427 | GPI-15427 is a potent PARP-1 inhibitor capable of crossing the blood-brain barrier, which can significantly increased the antitumor activity of the methylating agent TMZ against malignant melanoma, glioblastoma multiforme, or lymphoma growing at the CNS site. GPI-15427 acts as a potent inhibitor of the enzyme, being capable of inhibiting the activity of purified PARP-1 at nanomolar concentrations. GPI-15427 induced significant sensitization to radiotherapy, representing a promising new treatment in the management of HNSCC. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: GPI 15427; GPI15427; 10-((4-Methylpiperazin-1-yl)methyl)chromeno(4,3,2-de)phthalazin-3(2H)-one. CAS No. 805242-85-7. Molecular formula: C20H20N4O2. Mole weight: 348.41. |  |
| GPi 688 | GPi 688 is an allosteric glycogen phosphorylase inhibitor that inhibits glucagon-mediated hyperglycemia in the rat. Synonyms: GPi 688; GPi688; GPi-688; 2-Chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl]-6H-thieno[2,3-b]pyrrole-5-carboxamide. Grades: ≥99% by HPLC. CAS No. 918902-32-6. Molecular formula: C19H18ClN3O4S. Mole weight: 419.88. | |
| GPLGIAGQ | GPLGIAGQ, is an MMP2-cleaved polypeptide that is used as a stimulus-sensitive connector in both liposomes and micelle nanoceroses for targeted therapy of tumors triggered by MMP2. Synonyms: L-Glutamine, glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-; Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln. Grades: ≥97% by HPLC. CAS No. 109053-09-0. Molecular formula: C31H53N9O10. Mole weight: 711.81. | |
| GPNA hydrochloride | GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase ( GGT ). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na + -dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na + -independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67953-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W011391. | |
| g-Poly(glutamic acid) | PGA. Grades: biomedical grade. CAS No. 26747-79-0. Product ID: 8-01056. Mole weight: Mw typically >1,000,000 Da. Properties: intrinsic viscosity 0.15-0.25. |  |
| g-Poly-L-glutamic acid, sodium salt | g-Poly-L-glutamic acid, sodium salt. CAS No. 26747-79-0. Product ID: 6-00013. Molecular formula: -[CO(CH2)2CH(CO2H)NH]n. | |
| g-Poly-L-glutamic acid, sodium salt | g-Poly-L-glutamic acid, sodium salt. CAS No. 26747-79-0. Product ID: 7-00195. Molecular formula: -[CO(CH2)2CH(CO2Na)NH]n. Mole weight: Purity: monodisperse fractions, available in different molecular weights. Properties: temperature threshold: 30°C. | |
| GPP 78 | GPP 78 is a potent inhibitor of Nicotinamide phosphoribosyltransferase (Nampt) with an IC50 value of 3 nM. Synonyms: CAY10618; NMPRTase Inhibitor; N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-1H-1,2,3-triazole-1-octanamide. Grades: ≥95%. CAS No. 1202580-59-3. Molecular formula: C27H29N5O. Mole weight: 439.6. | |
| GPP 78 hydrochloride | GPP 78 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), which is subsequently converted to NAD+. It was shown to induce autophagy in neuroblastoma cells. Synonyms: GPP 78 hydrochloride; GPP78 hydrochloride; GPP-78 hydrochloride; N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C27H29N5O.HCl. Mole weight: 476.01. | |
| GPP 78 hydrochloride | GPP 78 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GppNH2 | GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPN; Guanosine-5'-(β-amino)-diphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C10H16N6O10P2. Mole weight: 442.21. | |
| GppNHp - Tetralithium salt | The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Tetralithium salt; GMPPNHP. Grades: ≥ 95 % by HPLC. CAS No. 64564-03-0. Molecular formula: C10H13N6ONa413P3. Mole weight: 611.13. | |
| GppNHp - Trisodium salt | The trisodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Trisodium salt; GMPPNHP. Grades: ≥ 90 % by HPLC. CAS No. 148892-91-5. Molecular formula: C10H14N6Na3O13P3. Mole weight: 588.14. | |
| GPR109b Agonist (1-(iso-Propyl)-1H-benzotriazole-5-carboxylic Acid) | A cell-permeable Niacin triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or b-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5uM) and isoproterenol (1uM), respectively, in GPR109b-expressing CHO cells (EC50=400nM) and freshly isolated human adipocytes (EC50 about 1uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 306935-41-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| GPR109b Agonist - CAS 306935-41-1 | The GPR109b Agonist, also referenced under CAS 306935-41-1, controls the biological activity of GPR109b. This small molecule/inhibitor is primarily used for Activators/Inducers applications. Group: Fluorescence/luminescence spectroscopy. |  |
| GPR119 Agonist, AS1269574 (G-Protein Coupled Receptor 119 Agonist, 2-((2-(4-Bromophenyl)-6-methylpyrimidin-4-yl)amino)ethanol, GPCR2 Agonist, MGC119957 Agonist, SNORF25 Agonist) | A pyrimidine compound that acts as an effective GPR119 agonist (EC50=2.5uM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward B-adrenergic or GLP-1 receptors. Shown to enhance 16.8mM glucose-induced insulin secretion from murine MIN-6 B-cells (mU/20 min=0.44 and 0.22, respectively, with or without 10uM AS1269574) in vitro and improve glucose tolerance in normal mice (100mg/kg; p.o.) without any significant hypoglycemic effect in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 330981-72-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR120-IN-1 | GPR120-IN-1, a cell-permeable azaspiroundecanyl acetic acid compound, is an orally available, selective agonist of GPR120 (EC50 = ~0.35 μM) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1). Synonyms: 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid; GPR120 Compound A; MDK77754; MDK-77754; MDK 77754; GPR120 cpdA. CAS No. 1599477-75-4. Molecular formula: C19H23ClF3NO3. Mole weight: 405.84. | |
| GPR120 modulator 1 | GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 1; 1050506-75-6; 2-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenoxy]acetic acidAcetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]-GPR120-modulator-1. Grades: >98%. CAS No. 1050506-75-6. Molecular formula: C19H16ClNO4S. Mole weight: 389.85. | |
| GPR120 modulator 2 | GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 2; 1050506-87-0; 3-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenyl]propanoic acidBenzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl-3-(4-{[4-(2-CHLOROPHENYL)-1,3-THIAZOL-2-YL]METHOXY}-2-METHYLPHENYL)PROPANOIC ACID. Grades: >98%. CAS No. 1050506-87-0. Molecular formula: C20H18ClNO3S. Mole weight: 387.88. | |
| GPR139 agonist-2 | GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC 50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2983118-29-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149651. | |
| GPR183-IN-2 | GPR183-IN-2 (compound 23) is a potent GPR183 inhibitor. GPR183-IN-2 inhibits Ca 2+ mobilization with an IC 50 value of 39.45 nM. GPR183-IN-2 has the potential for the research of cancer, autoimmune diseases, pain, and osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924064-10-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163796. | |
| GPR34 receptor antagonist | GPR34 receptor antagonist Inhibitor. Uses: Scientific use. Product Category: T8848. CAS No. 907952-06-1. |  |
| GPR35 agonist 5 | GPR35 agonist 5 (3,5-dinitro-bisphenol A; compound 6) is a weak GPR35 agonist. GPR35 agonist 5 arrests CHO-S cells at the G1/Gophase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226201-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149190. | |
| GPR35 Agonist, Compound 10 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GPR39-C3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GPR40 Activator 1 | GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. Synonyms: GPR40 Activator 1. Grades: >98%. CAS No. 1309435-60-6. Molecular formula: C31H31NO3S. Mole weight: 497.65. | |
| GPR40 Activator 2 | GPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. Synonyms: GPR40 Activator 2. Grades: >98%. CAS No. 1312787-30-6. Molecular formula: C28H29NO6S2. Mole weight: 539.66. | |
| GPR40 Agonist - CAS 885101-89-3 | The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. | |
| GPR40 Agonist II (FFA1 Agonist II, Free Fatty Acid Receptor 1 Agonist II, 3- (4- ( (2, 6-Dichloropyridin-4-yl) ethynyl) phenyl) propanoic Acid) | A cell-permeable alkynedihydrocinnamic acid that acts as a potent GPR40/FFA1 agonist (EC50=40.7nM in inducing Ca2+ mobilization in hFFA1-expressing 1321N1 cells) with >100-fold selectivity over GPR43/FFA2, GPR41/FFA3, and a panel of 56 other receptors, ion channels, and transporters. Reported to enhance 12mM glucose-induced insulin secretion from rat INS-1E B-cells (by 34% at 10uM) and exhibit good aqueous solubility (199uM in PBS at pH 7.4), as well as chemical and metabolic stability. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR40 Antagonist, GW1100 - CAS 306974-70-9 | The GPR40 Antagonist, GW1100, also referenced under CAS 306974-70-9, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy. | |
| GPR43 (FFA2) Agonist ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide) | A phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50=0.7uM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR55 agonist 3 | GPR55 agonist 3 (Compound 26) is a GPR55 agonist ( EC 50 : 0.239 nM, and 1.76 nM for hGPR55 and rGPR55). GPR55 agonist 3 induces β-arrestin recruitment to human GPR55 ( EC 50 : 6.2 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3006105-44-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156107. | |
| GPR55 Receptor Antagonist, CID16020046 (4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H-pyrrolo[3,4-c]pyrazol-5-yl]benzoic Acid) | A selective antagonist of G protein-coupled receptor 55 (GPR55) that blocks lipid L-a-lysophosphatidyl inositol (LPI)-induced GPR55 activation (IC50 = 1uM) and downstream effects in HEK293 cells. Also shown to block the agonistic effect of LPI on GPR55- expressing yeast cells (~10uM). Inhibits LPI-induced Ca2+ mobilization and ERK1/2 phosphorylation in HEK-GPR55 and HEK-CB1 cells. However, it does not affect basal Ca2+ mobilization and ERK1/2 activity. Blocks the GPR55-mediated NFAT and NF-kB activation and their nuclear translocation in HEK-GPR55 cells. Diminishes LPI-induced wound healing in GPR55-expressing primary human lung microvascular endothelial cells and reverses LPI-inhibited platelet aggregation (~10uM). Also reported to inhibit the activity of phosphodiesterases PDE3A and PDE4B (pIC50 = 5 and 4.8, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| GPR81 Agonist, 3Cl-5OH-BA (3-Chloro-5-hydroxybenzoic Acid, Hydroxycarboxylic Acid Receptor 1 Agonist) | A hydroxybenzoic acid compound that acts as a GPR81/HCA1-selective agonist (EC50 ~7, 16, 17, 22, and 67uM toward rat, human, monkey, mouse, and dog species, respectively) with little activity towards the homologous GPR109A/HCA2/HM74A GPCR. Orally active in mice and exhibits NEFAc cholesterol-lowering efficacy in overnight fasted C57B16/J mice (ED50 ~100mg/kg, p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 53984-36-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| gpr endopeptidase | Initiates the degradation of small, acid-soluble proteins during spore germination in Bacillus megaterium. Type example of peptidase family M63. Group: Enzymes. Synonyms: germination proteinase. Enzyme Commission Number: EC 3.4.24.78. CAS No. 75718-32-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4362; gpr endopeptidase; EC 3.4.24.78; 75718-32-0; germination proteinase. Cat No: EXWM-4362. |  |
| G Protein Antagonist | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| G-Protein antagonist peptide | G-Protein antagonist peptide is a competitive and reversible inhibitor of M2 muscarinic cholinergic receptors. G-Protein antagonist peptide inhibits M2 muscarinic receptor activation of Gi or Go and suppresses Gs activation by β-adrenoceptors. Synonyms: GPAnt-2; G Protein Antagonist. Grades: >98%. CAS No. 143675-79-0. Molecular formula: C57H64N12O9S. Mole weight: 1093.27. | |
| G-protein-coupled receptor kinase | Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate. (cf. EC 2.7.11.14, rhodopsin kinase and EC 2.7.11.15, β-adrenergic-receptor kinase). Group: Enzymes. Synonyms: G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Enzyme Commission Number: EC 2.7.11.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3135; G-protein-coupled receptor kinase; EC 2.7.11.16; G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Cat No: EXWM-3135. | |
| GPRP | GPRP is an inhibitor of fibrin polymerization. It binds to fibrinogen (Ki = 400 mM). Synonyms: Gly-pro-arg-pro; L-Proline,glycyl-L-prolyl-L-arginyl-; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid. CAS No. 67869-62-9. Molecular formula: C18H31N7O5. Mole weight: 425.48. | |
| GPV574 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GPX100 | GPX-100 is an analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. GPX-100 was designed to be a non-cardiotoxic anthracycline antibiotic. Synonyms: Epirubicin Impurity 1; 13-Deoxyepirubicin; GPX 100; GPX-100; 13-deoxy-doxorubicin; (1S,3R)-3,5,12-Trihydroxy-3-(2-hydroxyethyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-1-methoxy-, (8R,10S)-. Grades: ≥95%. CAS No. 952648-77-0. Molecular formula: C27H31NO10. Mole weight: 529.54. | |
| GPX150 | GPX-150 is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis. Synonyms: GPX 150; GPX-150; 5(8H)-Naphthacenone, 10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-, (8R,10S)-. CAS No. 236095-29-7. Molecular formula: C27H32N2O9. Mole weight: 528.56. | |
| GPX1 human | recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| GQ-16 | GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARγ , exhibiting a K i of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPAR&gamma. GQ-16 is a partial agonist of PPARγ with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 870554-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111254. | |
| GQ-16 | GQ-16 is an effective and partial agonist for peroxisome proliferator-activated receptor γ (PPARγ) (Ki = 160 nM). It does not activate PPARα, PPARβ/δ, or RXR&alpha. Synonyms: 5Z-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione. Grades: ≥98%. CAS No. 870554-67-9. Molecular formula: C19H16BrNO3S. Mole weight: 418.3. | |
| GQ1b-Ganglioside | GQ1b-Ganglioside is a vital biomedical product utilized for its neuroprotective properties. This compound acts as a crucial element in the treatment of various neurological disorders, including Guillain-Barré syndrome and Miller Fisher syndrome. Synonyms: Tetrasialoganglioside 1b. CAS No. 68652-37-9. Molecular formula: C106H182N6O56 4H3N. Mole weight: 2504.71. | |
| GQ3-Oligosaccharide | GQ3-Oligosaccharide is an extraordinary bioactive compound employed in the research of neurodegenerative ailments, showcasing remarkable neuroprotective attributes. GQ3-Oligosaccharide actively contributes to the diminution of oxidative stress and inflammation, thereby facilitating the augmentation of neuronal viability and efficacious functioning. Synonyms: Neu5Aca2-8Neu5Aca2-8Neu5Acb2-8Neu5Aca2-3Galb1-4Glc. Molecular formula: C56H86N4O43Na4. Mole weight: 1595.24. | |
| GR 103691 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| GR 103691 | GR 103691 is a potent dopamine D3 receptor antagonist. Uses: Dopamine antagonists. Synonyms: GR 103691; GR103691; GR-103691; 4'-Acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide. Grades: 99%. CAS No. 162408-66-4. Molecular formula: C30H35N3O3. Mole weight: 485.62. | |
| GR 113808 | GR 113808 is a potent and highly selective 5-HT 4 receptor antagonist ( pK b = 8.8). GR 113808 shows 300-fold selectivity over 5-HT 1A , 5-HT 1B , 5-HT 2A , 5-HT 2C and 5-HT 3 receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 144625-51-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103152. | |
| GR 113808 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| GR 113808 | GR 113808 is a potent and selective 5-HT4 receptor antagonist (pKB = 9.43 in human colonic muscle, Kd=0.15 nM for binding to cloned human 5-HT4 receptors). GR 113808 displays > 300-fold selectivity for 5-HT4 over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Uses: Serotonin antagonists. Synonyms: GR 113808; GR113808; GR-113808. 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester. Grades: ≥98% by HPLC. CAS No. 144625-51-4. Molecular formula: C19H27N3O4S. Mole weight: 393.5. | |
| GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808) | A potent and selective antagonist of the serotonin 5-HT4 receptor (pki = 9.3-10.3). GR113808 is commonly used in brain and peripheral in vitro and in vivo in striatum studies (Guinea pig IC50 = 113nM, rat brain membrane Kd = 0.4-1nM) and in cAMP response in CHO and C6 glial cells (EC50 = 79-81nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 144625-51-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| GR 125487 sulfamate | GR 125487, a potent and selective 5-HT4 antagonist, is used in many biological assays to cross confirm the 5-HT4R agonist's activity. Synonyms: GR 125487 sulfamate; GR 125487; GR125487; GR-125487. 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate. Grades: ≥97% by HPLC. CAS No. 859502-43-5. Molecular formula: C19H26FN3O5S.H2NSO3H. Mole weight: 524.58. | |
| GR 127935 hydrochloride | GR 127935 hydrochloride is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrochloride (1:1); [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, monohydrochloride; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide hydrochloride; GR127935 hydrochloride; GR-127935 hydrochloride. Grades: ≥99% by HPLC. CAS No. 148642-42-6. Molecular formula: C29H31N5O3.HCl. Mole weight: 534.06. | |
| GR127935 hydrochloride | GR127935 hydrochloride is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148642-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100794. | |
| GR 127935 Hydrochloride (5-HT1B/1D Serotonin Receptor Antagonist, GR 127935 Hydrochloride, GR-127935 Hydrochloride, GR127935 Hydrochloride) | A selective 5-HT1B/1D receptor antagonist. Selectivity was found to be similar for B (pki = 9.2-9.8) and D (pki = 8.6-9.1) receptor types. GR 127935 works well in vivo and was shown to block (+)-MDMA-induced hyperactivity in rats. It alters release of serotonin in the brain, as well as reducing drug-seeking behavior in cocaine addicted rats. In transformed rat C5 glioma cells, this inhibitor blocked 5HT with an IC50 = 97pM. Group: Biochemicals. Grades: Highly Purified. CAS No. 148642-42-6. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences. | Worldwide |
| GR 127935 hydrochloride hydrate | >98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| GR 135402 | A novel antifungal antibiotic GR 135402 has been isolated from a Graphium putredinis which inhibited protein synthesis in Candida albicans but not rabbit reticulocytes. Synonyms: Antibiotic GR135402; GR135402. CAS No. 204199-15-5. Molecular formula: C34H48O9. Mole weight: 600.74. | |
| GR 135531 | GR 135531. Group: Biochemicals. Grades: Purified. CAS No. 190277-13-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GR 135531 | GR 135531 is a high affinity agonist of MT3 melatonin receptors, with low affinity for MT1 and MT2 melatonin receptors. GR 135531 can be used to discriminate between the melatonin receptor subtypes. Synonyms: GR 135531; GR135531; GR-1355315-Methoxycarbonylamino-N-acetyltryptamine; 5-MCA-NAT; methyl N-[3-(2-acetamidoethyl)-1H-indol-5-yl]carbamate. Grades: ≥97% by HPLC. CAS No. 190277-13-5. Molecular formula: C14H17N3O3. Mole weight: 275.31. | |
| GR 144053 trihydrochloride | GR 144053 trihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1215333-48-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GR 144053 trihydrochloride | GR 144053 trihydrochloride is a potent and selective orally bioactive platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC50 = 37 nM). GR 144053 potently inhibits thrombus formation in vivo. Synonyms: GR 144053; GR-144053; GR144053; GR 144053 trihydrochloride. 4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride. Grades: ≥99% by HPLC. CAS No. 1215333-48-4. Molecular formula: C18H27N5O2.3HCl. Mole weight: 454.83. | |
| GR 159897 | GR 159897 is a potent and selective neurokinin NK2 receptor antagonist. GR 159897 competes for binding of [3H]GR100679 to hNK2-transfected CHO cells (pKi = 9.5). Study shows that GR 159897 inhibits NK2 receptor-mediated contraction of guinea pig trachea. Synonyms: GR 159897; GR159897; GR-159897; 5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole. Grades: ≥97% by HPLC. CAS No. 158848-32-9. Molecular formula: C23H27FN2O2S. Mole weight: 414.54. | |
| GR203040 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GR 203040 | GR 203040 is a selective NK1 receptor antagonist with high affinity. GR 203040 potently inhibits substance P binding to NK1 receptors (pKi = 10.1 to 10.5). Synonyms: (2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 168398-02-5. Molecular formula: C20H24N6O·2HCl. Mole weight: 437.37. | |
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