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Cell-permeable. A small molecule pan-Bcl-2 antagonist that mimics BH3-only proteins by binding to multiple antiapoptotic Bcl-2 members. GX15-070 has been shown to overcome Bcl-2-, Bcl-xl-, Bcl-w-, and Mcl-1-mediated resistance to Bax or Bak. It potently interferes with the direct interaction between Mcl-1 and Bak in intact outer mitochondrial membrane and inhibits the association between Mcl-1 and Bak in intact cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 803712-79-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
GX-674
GX-674 is a Nav1.7 antagonist in the aryl sulfonamide class with higher selectivity for Nav1.7 (IC50= 0.1nM) over other Nav subtypes. Nav1.7 is commonly expressed in olfactory epithelium, sympathetic ganglion, and dorsal root ganglion sensory neurons. GX-674 has the potential to alleviate extreme pains. Synonyms: GX-674; GX674;GX 674; 4-(2-(2-Amino-1H-benzo[d]imidazol-5-yl)-4-chlorophenoxy)-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide. CAS No. 1432913-36-4. Molecular formula: C21H13ClF2N6O3S2. Mole weight: 534.94.
GXpep-3
GXpep-3 is a novel polypeptide inhibitor of phospholipid hydroperoxidase glutathione peroxidase (GPX4). Currently GPX4 is found to be a target which selectively induces iron-dependent cell death (ferroptosis) in cancer cells that express mutant Ras. GXpep-3 is promisingly developed to be a antitumor drug. Uses: Antitumor. Synonyms: GXpep 3; GXpep3.
Gyki 13324
GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. It can produce long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, seems to be a candidate in the clinical management of colorectal tumors. Uses: Colorectal tumor. Synonyms: GYKI-13324; GYKI 13324; GYKI13324. N- (2-Chloroethyl) -N'- (4- ( ( ( (2-chloroethyl) amino) carbonyl) nitrosamino) -2, 3-dihydroxybutyl) -N-nitrosourea. Grades: 98%. CAS No. 76123-41-6. Molecular formula: C10H18Cl2N6O6. Mole weight: 389.19.
GYKI-13380
GYKI-13380is a bio-active compound. But no detailed information has been published ye. Synonyms: GYKI-13380; GYKI 13380; GYKI13380; LS-79445; LS 79445; LS79445. 4-((3-(Cyclopentyloxy)-4-methoxyphenyl)methyl)-2-imidazolidinone. Grades: 98%. CAS No. 75614-09-4. Molecular formula: C16H22N2O3. Mole weight: 290.36.
GYKI 14166
Efegatran is a thrombin inhibitor under the development of Eli Lilly. It can be used for the treatment of thromboembolic disorders. No development reported was reported for the treatment of Thrombosis. Uses: Thrombosis. Synonyms: Efegatran; RGH 2958; LY 294468; GYKI 14166; RGH2958; LY294468; GYKI14166; RGH-2958; LY-294468; GYKI-14166; (S)-1-(D-phenylalanyl)-N-((S)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide sulfate. Grades: 98%. CAS No. 83997-16-4. Molecular formula: C20H30N6O3.H2O4S. Mole weight: 500.57.
GYKI14451
GYKI14451 is a synthetic tripeptide inhibitor of thrombin. It has anti-atherosclerotic activity. Uses: Gyki14451 has anti-atherosclerotic activity. Synonyms: GYKI-14451; GYKI14451; LY-178207; GYKI 14451;LY 178207; LY178207;Boc-D-Phe-Pro-Arg-H;Tert-butyl ((R)-1-((S)-2-(((S)-5-guanidino-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate. Grades: 98%. CAS No. 69201-89-4. Molecular formula: C25H38N6O5. Mole weight: 502.61.
GYKI-14451 sulfate
GYKI-14451 is a synthetic tripeptide inhibitor of thrombin.It has anti-atherosclerotic activity. Uses: Thrombosis. Synonyms: GYKI-14451 sulfate; GYKI 14451 sulfate; GYKI14451 sulfate; tert-butyl ((R)-1-((S)-2-(((S)-5-guanidino-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate hemisulfate; LY 178207; LY178207; LY-178207; Boc-D-Phe-Pro-Arg-H;69201-89-4 (free base). Grades: 98%. CAS No. 83861-29-4. Molecular formula: C50H76N12O10.H2O4S. Mole weight: 1103.30.
GYKI-16084
GYKI-16084 is a postsynaptic alpha2-blocker with the potential to treat benign prostatic hyperplasia. Synonyms: 2-[3-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methylamino]propyl]pyridazin-3-one; GYKI16084; GYKI 16084; GYKI-16084R-2-(3-N-(2-benzo(1,4)dioxanylmethyl)-amino-1-propyl)-3(2H)-pyridazinone hydrochloride. Grades: >98%. CAS No. 185739-21-3. Molecular formula: C16H19N3O3. Mole weight: 301.346.
GYKI-16638
GYKI-16638 is Potassium channel and Sodium channel antagonist originated by Nonindustrial source. It is a novel antiarrhythmic agent. Uses: Arrhythmias. Synonyms: GYKI-16638; GYKI 16638; GYKI16638; N- (4- (2- ( (1- (2, 6-dimethoxyphenoxy) propan-2-yl) (methyl) amino) ethyl) phenyl) methanesulfonamide. Grades: 98%. CAS No. 778564-77-5. Molecular formula: C21H30N2O5S. Mole weight: 422.54.
GYKI-16638 HCl
GYKI-16638 is a novel antiarrhythmic agent, shows combined Class IB and Class III antiarrhythmic properties, resembling the electrophysiological manifestation seen after chronic amiodarone treatment. Uses: A novel antiarrhythmic agent. Synonyms: GYKI-16638 HCl; GYKI 16638 HCl; GYKI16638 HCl; N- [4- [2- [1- (2, 6-dimethoxyphenoxy) propan-2-yl-methylamino] ethyl] phenyl] methanesulfonamide; hydrochloride. Grades: ≥98%. CAS No. 307556-59-8. Molecular formula: C21H31ClN2O5S. Mole weight: 458.998.
GYKI-20238
GYKI-20238 is a thiazolidine compound with anti-amnesic activity. Uses: Anti-amnesic. Synonyms: GYKI-20238; GYKI20238; GYKI 20238; GYKI-20,238; GYKI20,238; GYKI 20,238. 2-Methylimino-3-(2,6-dichlorophenyl)-4-methylthiazolidine. Grades: ≥96%. CAS No. 30725-74-7. Molecular formula: C11H12Cl2N2S. Mole weight: 274.01.
GYKI-23107
GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine; GYKI-23107; GYKI 23107; GYKI23107. Grades: 98%. CAS No. 83843-49-6. Molecular formula: C13H22N2. Mole weight: 206.33.
GYKI-23107 dihydrochloride
GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: GYKI-23107 dihydrochloride; GYKI 23107 dihydrochloride; GYKI23107 dihydrochloride; 83843-49-6 (free base);N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine dihydrochloride. Grades: 98%. CAS No. 83843-39-4. Molecular formula: C13H24Cl2N2. Mole weight: 279.25.
GYKI-46903 HCl
GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron binding to rat cerebral cortex membranes were 6.91. No development was reported for the treatment of Cognition disorders, Nausea and vomiting. Uses: Cognition disorders; nausea and vomiting. Synonyms: GYKI-46903; GYKI 46903; GYKI46903; GYKI-46,903; GYKI 46,903; GYKI46,903; (4R,5R)-6-(4-fluorophenyl)-1-azabicyclo[3.3.1]non-6-en-4-yl propionate hydrochloride. Grades: 98%. CAS No. 142999-59-5. Molecular formula: C17H21ClFNO2. Mole weight: 325.81.
GYKI-47261
GYKI-47261 is a non-competitive AMPA receptor antagonist (IC50 = 2.5 μM) and a CYP2E1 inducer. GYKI-47261 shows broad spectrum anticonvulsive activity and neuroprotective effects in vivo. Synonyms: 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline; GYKI 47261; GYKI47261; GYKI-47261. Grades: >99 %. CAS No. 220445-20-5. Molecular formula: C18H15ClN4. Mole weight: 322.796.
GYKI 47261 dihydrochloride
GYKI 47261 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1217049-32-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GYKI 47261 dihydrochloride
This active molecular is Non-competitiv a AMPA antagonist with IC50 value of 2.5 μM. GYKI-47261 is also a CYP2E1 inducer. GYKI-47261 showed broad spectrum of anticonvulsive and really good neuroprotective effect in vivo. AMPA and NMDA receptors have been implicated in the regulation of corticostriatal synaptic efficacy which abundantly expressed on striatal medium spiny neurons. In 2000, preclinical development for Epilepsy in Hungar was on-going, but no development was reported yet. Uses: Epilepsy; parkinson's disease; stroke. Synonyms: GYKI 47261 dihydrochloride; GYKI47261 dihydrochloride; GYKI-47261 dihydrochloride; 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline;dihydrochloride;220445-20-5 (free base). Grades: 98%. CAS No. 1217049-32-5. Molecular formula: C18H17Cl3N4. Mole weight: 395.71.
GYKI-52466
GYKI-52466 is a non-competitive AMPA receptor antagonist. It belongs to 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist. It has anticonvulsant and neuroprotective properties. It is an orally-active anticonvulsant and skeletal muscle relaxant. It also was found to have therapeutic potential for cocaine addiction treatment. Uses: Gyki-52466 is an orally-active anticonvulsant and skeletal muscle relaxant. it also was found to have therapeutic potential for cocaine addiction treatment. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline;GYKI-52466; GYKI52466; GYKI 52466; GYKI-5,2466; GYKI52,466; GYKI 52,466. Grades: >99 %. CAS No. 102771-26-6. Molecular formula: C17H15N3O2. Mole weight: 293.33.
GYKI 52466 dihydrochloride
GYKI 52466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 102771-26-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 10-20uM) over kainate (IC50 ~450uM) and nMDA (IC50 >> 50uM) receptors. Commonly used as neuroprotectant, anticonvulsant, and skeletal muscle relaxant. Biologically viable admitted orally or systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 102771-26-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
GYKI 53655
GYKI 53655 is a selective AMPA receptor antagonist with anticonvulsant activity. Synonyms: GYKI 53655; GYKI53655; GYKI-53655; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide. Grades: 99%. CAS No. 143692-18-6. Molecular formula: C19H20N4O3. Mole weight: 352.39.
GYKI 53655 hydrochloride
GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist displaying anticonvulsant activity. It also acts as a blocker of GluK3 homomeric receptors (IC50 = 63 μM) and GluK2b(R)/GluK3 heteroreceptors (IC50 = 32 μM) at high concentrations. GYKI 53655 prolongs the survival time after MgCl2- induced global cerebral ischemia. Synonyms: GYKI53655 Hydrochloride; GYKI53655 HCl; GYKI53655; GYKI 53655; GYKI-53655. LY 300168 hydrochloride; LY300168 hydrochloride; LY-300168 hydrochloride; 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 143692-48-2. Molecular formula: C19H20N4O3.HCl. Mole weight: 388.85.
GYKI 53655 Hydrochloride
A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 6 and 5uM for GluA1 and GluA4, respectively) over kainate receptors (IC50 = 63 and 32uM for GluK3 and GluK2b/GluK3 receptors. Used as neuroprotectant and anticonvulsant, and a valuable tool for the study of AMPA receptor-mediated processes in vivo. Group: Biochemicals. Alternative Names: LY 300168, GYKI-53655 Hydrochloride, AMPA Glutamate Receptor Antagonist, GYKI 53655 Hydrochloride, 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride. Grades: Highly Purified. CAS No. 143692-48-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
GYKI 53784
GYKI-53784, a dioxolbenzene derivative, has been found to be a AMPA receptor antagonist that could block excitotoxicity and decrease auditory nerve activity at some extent. Synonyms: GYKI-53784; GYKI53784; GYKI 53784; LY 303070; LY-303070; LY303070; 7H-1,3-Dioxolo(4,5-h)(2,3)benzodiazepine-7-carboxamide, 8,9-dihydro-5-(4-aminophenyl)-N,8-dimethyl-, (R)-; UNII-91N8O25H4L; AC1MIO7T. Grades: 98%. CAS No. 161832-71-9. Molecular formula: C19H20N4O3. Mole weight: 352.39.
Gymnema (Gymnema sylvestre) is an herb native to the tropical forests of southern and central India and Sri Lanka. Applications: Gymnema extract is one of the major botanicals being administered for those suffering from diabetes, in boosting insulin levels and controlling healthy blood sugar levels. it has unique property to directly mask the tongue's ability to taste sweet foods, at the same time suppresses glucose absorption from the intestine. Group: Others. CAS No. 122168-40-5. Purity: 25.0% 75.0% Gymnemic acid HPLC. Mole weight: 806.445257 g/mol. Gymnema Extract (Standard); 122168-40-5; C43H66O14. Cat No: EXTW-004.
Gymnemagenin
Gymnemagenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 22467-07-8. Pack Sizes: 10mg. Molecular Formula: C30H50O6, Molecular Weight: 506.72. US Biological Life Sciences.
Worldwide
Gymnema Sylvestre Extract
Gymnema Sylvestre Extract. Applications: Used for health care products, dietary supplements, reduce hypoglycemic activity. Group: Others. Synonyms: Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult. CAS No. 1399-64-0. Purity: 25%, 75% Gymnemic Acid By UV. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Gymnema sylvestre ?Retz.? Schult. Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-098.
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 122168-40-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Gymnestrogenin
Gymnestrogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19942-02-0. Pack Sizes: 5mg. Molecular Formula: C30H50O5, Molecular Weight: 490.73. US Biological Life Sciences.
Worldwide
Gymnestrogenin
Gymnestrogenin is a triterpenoid compound found in the Gymnema sylvestre. with dual LXRα/β antagonistic property. Synonyms: (3S, 4aS, 5S, 6aR, 6aS, 6bR, 8aR, 9R, 10S, 12aR, 14bS)-4a, 9-bis(hydroxymethyl)-2, 2, 6a, 6b, 9, 12a-hexamethyl-1, 3, 4, 5, 6, 6a, 7, 8, 8a, 10, 11, 12, 13, 14b-tetradecahydropicene-3, 5, 10-triol. Grades: >98%. CAS No. 19942-02-0. Molecular formula: C30H50O5. Mole weight: 490.725.
Gymnin
Gymnin is a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill). Gymnin exerts antifungal activity against F.oxysporum and M.arachidicola, with an IC50 of 2 μM for the former fungus and 10 μM, respectively. It inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase.
Gynostemma extract is prepared from the leaf of Gynostemma, a cucurbitaceous plant belongs to perennial grass nature lianas grows in the southeastern regions of China. Gynostemma pentaphyllum extract contains more than 80 different saponins, so is also known as southern ginseng. Gynostemma extract gypenoside is widely used as an anti aging supplement, or a tonic to treat bronchitis, strengthen the body, reduce fatigue, and reinforce overall health. Group: Others. Gynostemma Extract; Gynostemma Pentaphyllum Thunb. Cat No: EXTC-023.
gynostemma pentaphylla extractive
light yellow grown powder. Group: Material of health food. Grades: 20%, 80%. CAS No. 15588-68-8. Molecular formula: C80H126O44. Mole weight: 1791.83.
Gypenoside a. Group: Heterocyclic Organic Compound. Alternative Names: GYPENOSIDE A;(3beta,21S)-3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-3)]-alpha-L-arabinopyranosyl)oxy]-21,23-epoxy-20,21-dihydroxydammar-24-en-19-al. CAS No. 157752-01-7. Molecular formula: C46H74O17. Mole weight: 0.
Gypenoside I
Gypenoside I is an intricate phytochemical abundantly occurring in the plant known as Gynostemma Pentaphyllum. The multifaceted potential of Gypenoside I resides in its astonishingly promising capacity to potentially study a diverse array of maladies, which encompass the realms of cancer, diabetes, inflammation, as well as cardiovascular disorders. CAS No. 85889-20-9. Molecular formula: C46H78O18. Mole weight: 919.1.
Gypenoside XLIX. Group: Biochemicals. Grades: Plant Grade. CAS No. 94987-08-3. Pack Sizes: 20mg. Molecular Formula: C52H86O21, Molecular Weight: 1047.23. US Biological Life Sciences.
Worldwide
Gypenoside XLIX
Gypenoside XLIX inhibits LPS-induced TF overexpression and enhancement of its activity in human THP-1 monocytic cells via PPAR-alpha-dependent pathways. Synonyms: Gypenoside XLIX; (3beta)-3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-3)]-alpha-L-arabinopyranosyl)oxy]-21-(beta-D-glucopyranosyloxy)-20-hydroxy-dammar-24-en-19-al. Grades: >98%. CAS No. 94987-08-3. Molecular formula: C52H86O21. Mole weight: 1047.23.
Gypenoside xlvi
Gypenoside xlvi. Group: Heterocyclic Organic Compound. Alternative Names: Gypenoside XLVI;(2alpha,3beta,12beta)-20-(beta-D-Glucopyranosyloxy)-2,12-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside. CAS No. 94705-70-1. Molecular formula: C48H82O19. Mole weight: 0.
Gypenoside XLVI
Gypenosides are triterpenoid saponins isolated from Gynostemma pentaphyllum. Synonyms: Gypenoside XLVI; 94705-70-1; GypenosideXLVI; 2-[2-[[2,12-Dihydroxy-4,4,8,10,14-pentamethyl-17-[6-methyl-2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol; HY-N6252. Grades: >98%. CAS No. 94705-70-1. Molecular formula: C48H82O19. Mole weight: 963.15.
Gypenoside XLVI
Gypenoside XLVI. Group: Biochemicals. Grades: Plant Grade. CAS No. 94705-70-1. Pack Sizes: 10mg. Molecular Formula: C48H82O19, Molecular Weight: 963.16. US Biological Life Sciences.
Worldwide
Gypenoside-xvii
Gypenoside-xvii. Group: Heterocyclic Organic Compound. Alternative Names: GYPENOSIDE-XVII;3β-(β-D-Glucopyranosyloxy)-12β-hydroxy-5α-dammar-24-en-20-yl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside;(3beta,12beta)-3-(beta-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside;Gynosaponin S. CAS No. 80321-69-3. Molecular formula: C48H82O18. Mole weight: 947.158. Density: 1.38.
Gypenoside XVII
Gypenoside XVII. Group: Biochemicals. Alternative Names: Gynosaponin S. Grades: Plant Grade. CAS No. 80321-69-3. Pack Sizes: 20mg. Molecular Formula: C48H82O18, Molecular Weight: 947.154. US Biological Life Sciences.
Worldwide
Gypsetin
It is produced by the strain of Nannizzia gypsea var. incurvata IFO 9228. It can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with IC50 of 18 μmol/L, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μmol/L. It also inhibits [14C] oleic acid from forming cholesterol esters with IC50 of 0.65 μmol/L. Synonyms: Gypsetine; (-)-Gypsetin; 8a, 16a-Dihydroxy-5a, 13a-bis (1, 1-dimethylallyl)- (1)-benzazolidine- (3''', 2''': 4'', 5'')azolidino- (1'', 2'': 4', 5') (1, 4)perhydrodiazin- (1', 2': 1, 5)azolidino- (2, 3-b)- (1)-benzazolidine-7, 15-dione; Pyrazino(1'', 2'':1, 5;4'', 5'':1', 5')dipyrrolo(2, 3-b:2', 3'-b')diindole-7, 15(5H, 7aH)-dione, 5a, 13a-bis(1, 1-dimethyl-2-propenyl)-5a, 8, 8a, 13, 13a, 15a, 16, 16a-octahydro-8a, 16a-dihydroxy-, (5aalpha, 7aalpha, 8abeta, 13abeta, 15aalpha, 16aalpha)-. CAS No. 155114-38-8. Molecular formula: C32H36N4O4. Mole weight: 540.66.
Gypsogenic acid
Gypsogenic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 5143-5-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Gypsogenin 3-O- β-D-glucuronopyranoside
Gypsogenin 3-O- β-D-glucuronopyranoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 96553-02-5. Pack Sizes: 10mg. Molecular Formula: C36H54O10, Molecular Weight: 646.82. US Biological Life Sciences.
Worldwide
gypsogenin-3-O-glucuronide
Methyl gypsogenin 3-O-beta-D-glucuronopyranoside can be isolated from the seeds of Momordica cochinchinensis. Synonyms: Methyl(gypsogenin-3-O-β-D-gluco pyranoside)uronate; gypsogenin-3-O-β-D-glucopyranosideuronate; (3beta,4alpha)-17-Carboxy-23-oxo-28-norolean-12-en-3-yl-beta-D-glucopyranosiduronic acid 6-methyl ester; Methyl gypsogenin 3-O-beta-D-glucuronopyranoside. Grades: >98%. CAS No. 96553-02-5. Molecular formula: C37H56O10. Mole weight: 660.83.
Gypsum. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS001853. Shipping: Room Temperature.
Gypsum byproduct
Gypsum byproduct. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS001854. Shipping: Room Temperature.
Gypsum (NIM-GBW03111)
Gypsum (NIM-GBW03111). Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS008571. Shipping: Room Temperature.
Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism. Group: Biochemicals. Grades: Highly Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H16NO2PS2 C4H9NO. US Biological Life Sciences.
Worldwide
GYY 4137 morpholine salt
GYY 4137 morpholine salt. Group: Biochemicals. Grades: Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GYY-4137 Morpholine salt
GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Synonyms: GYY4137; GYY-4137; GYY 4137; GYY 4137 morpholine salt; ZYJ1122; ZYJ 1122; ZYJ-1122. GYY4137 Morpholine salt;(4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine;ZYJ1122 morpholine salt;ZYJ-1122 morpholine salt. Grades: ≥95%. CAS No. 106740-09-4. Molecular formula: C15H25N2O3PS2. Mole weight: 376.47.
GZD824
GZD824 potently suppressed proliferation of Bcr-Abl-positive K562 and Ku812 human CML cells with IC(50) values of 0.2 and 0.13 nM, respectively. It also displayed good oral bioavailability (48.7%), a reasonable half-life (10.6 h), and promising in vivo antitumor efficacy. GZD824 induced tumor regression in mouse xenograft tumor models driven by Bcr-Abl(WT) or the mutants and significantly improved the survival of mice bearing an allograft leukemia model with Ba/F3 cells harboring Bcr-Abl(T315I). Synonyms: GZD824; GZD 824; GZD-824. Grades: >98%. CAS No. 1257628-77-5. Molecular formula: C29H27F3N6O. Mole weight: 532.56.
GZD824 Dimesylate
GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively. Synonyms: Olverembatinib dimesylate; HQP1351 dimesylate; GZD 824 Dimesylate; GZD-824 Dimesylate; 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide dimethanesulfonate; Benzamide, 4-methyl-N-(4-((4-methyl-1-piperazinyl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(1H-pyrazolo(3,4-b)pyridin-5-yl)ethynyl)-, methanesulfonate (1:2). Grades: ≥99%. CAS No. 1421783-64-3. Molecular formula: C29H27F3N6O.2CH4O3S. Mole weight: 724.77.