A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). Synonyms: GR-103545 fumarate; (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate; (R)-(-)-GR103545 fumarate. CAS No. 126766-43-6. Molecular formula: C23H29Cl2N3O7. Mole weight: 530.40.
GR 103691
GR 103691 is a potent dopamine D3 receptor antagonist. Uses: Dopamine antagonists. Synonyms: GR 103691; GR103691; GR-103691; 4'-Acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide. Grade: 99%. CAS No. 162408-66-4. Molecular formula: C30H35N3O3. Mole weight: 485.62.
GR 113808 is a potent and highly selective 5-HT 4 receptor antagonist ( pK b = 8.8). GR 113808 shows 300-fold selectivity over 5-HT 1A , 5-HT 1B , 5-HT 2A , 5-HT 2C and 5-HT 3 receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 144625-51-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103152.
GR 113808
GR 113808 is a potent and selective 5-HT4 receptor antagonist (pKB = 9.43 in human colonic muscle, Kd=0.15 nM for binding to cloned human 5-HT4 receptors). GR 113808 displays > 300-fold selectivity for 5-HT4 over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Uses: Serotonin antagonists. Synonyms: GR 113808; GR113808; GR-113808. 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester. Grade: ≥98% by HPLC. CAS No. 144625-51-4. Molecular formula: C19H27N3O4S. Mole weight: 393.5.
GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808)
A potent and selective antagonist of the serotonin 5-HT4 receptor (pki = 9.3-10.3). GR113808 is commonly used in brain and peripheral in vitro and in vivo in striatum studies (Guinea pig IC50 = 113nM, rat brain membrane Kd = 0.4-1nM) and in cAMP response in CHO and C6 glial cells (EC50 = 79-81nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 144625-51-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
GR 125487-d3 sulfamate
GR 125487-d3 sulfamate is a deuterated salt form of GR 125487, which is a potent 5-HT4 receptor antagonist used for the treatment of gastrointestinal motility. Synonyms: 5-Fluoro-2-methoxy-d3-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate. Grade: 96% by HPLC; 99% atom D. Molecular formula: C19H23D3FN3O5S.H2NSO3H. Mole weight: 527.6.
GR 125487 sulfamate
GR 125487, a potent and selective 5-HT4 antagonist, is used in many biological assays to cross confirm the 5-HT4R agonist's activity. Synonyms: GR 125487 sulfamate; GR 125487; GR125487; GR-125487. 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate. Grade: ≥97% by HPLC. CAS No. 859502-43-5. Molecular formula: C19H26FN3O5S.H2NSO3H. Mole weight: 524.58.
GR-125743
GR-125743 is a novel 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively. It is used for the research of Parkinson's disease and cardiovascular diseases. Synonyms: N-(4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)-3-methyl-4-(pyridin-4-yl)benzamide; GR 125743. Grade: >99%. CAS No. 148547-33-5. Molecular formula: C25H28N4O2. Mole weight: 416.52.
GR 127935
GR 127935 is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting >100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Uses: Serotonin antagonists. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide; GR127935; GR-127935. Grade: ≥95%. CAS No. 148672-13-3. Molecular formula: C29H31N5O3. Mole weight: 497.59.
GR 127935 hydrochloride
GR 127935 hydrochloride is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrochloride (1:1); [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, monohydrochloride; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide hydrochloride; GR127935 hydrochloride; GR-127935 hydrochloride. Grade: ≥99% by HPLC. CAS No. 148642-42-6. Molecular formula: C29H31N5O3.HCl. Mole weight: 534.06.
GR127935 hydrochloride
GR127935 hydrochloride is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148642-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100794.
GR 127935 Hydrochloride (5-HT1B/1D Serotonin Receptor Antagonist, GR 127935 Hydrochloride, GR-127935 Hydrochloride, GR127935 Hydrochloride)
A selective 5-HT1B/1D receptor antagonist. Selectivity was found to be similar for B (pki = 9.2-9.8) and D (pki = 8.6-9.1) receptor types. GR 127935 works well in vivo and was shown to block (+)-MDMA-induced hyperactivity in rats. It alters release of serotonin in the brain, as well as reducing drug-seeking behavior in cocaine addicted rats. In transformed rat C5 glioma cells, this inhibitor blocked 5HT with an IC50 = 97pM. Group: Biochemicals. Grades: Highly Purified. CAS No. 148642-42-6. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences.
A novel antifungal antibiotic GR 135402 has been isolated from a Graphium putredinis which inhibited protein synthesis in Candida albicans but not rabbit reticulocytes. Synonyms: Antibiotic GR135402; GR135402. CAS No. 204199-15-5. Molecular formula: C34H48O9. Mole weight: 600.74.
GR 135531
GR 135531. Group: Biochemicals. Grades: Purified. CAS No. 190277-13-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GR 135531
GR 135531 is a high affinity agonist of MT3 melatonin receptors, with low affinity for MT1 and MT2 melatonin receptors. GR 135531 can be used to discriminate between the melatonin receptor subtypes. Synonyms: GR 135531; GR135531; GR-1355315-Methoxycarbonylamino-N-acetyltryptamine; 5-MCA-NAT; methyl N-[3-(2-acetamidoethyl)-1H-indol-5-yl]carbamate. Grade: ≥97% by HPLC. CAS No. 190277-13-5. Molecular formula: C14H17N3O3. Mole weight: 275.31.
GR 144053 trihydrochloride
GR 144053 trihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1215333-48-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GR 144053 trihydrochloride
GR 144053 trihydrochloride is a potent and selective orally bioactive platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC50 = 37 nM). GR 144053 potently inhibits thrombus formation in vivo. Synonyms: GR 144053; GR-144053; GR144053; GR 144053 trihydrochloride. 4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride. Grade: ≥99% by HPLC. CAS No. 1215333-48-4. Molecular formula: C18H27N5O2.3HCl. Mole weight: 454.83.
GR 159897
GR 159897 is a potent and selective neurokinin NK2 receptor antagonist. GR 159897 competes for binding of [3H]GR100679 to hNK2-transfected CHO cells (pKi = 9.5). Study shows that GR 159897 inhibits NK2 receptor-mediated contraction of guinea pig trachea. Synonyms: GR 159897; GR159897; GR-159897; 5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole. Grade: ≥97% by HPLC. CAS No. 158848-32-9. Molecular formula: C23H27FN2O2S. Mole weight: 414.54.
GR 203040 is a selective NK1 receptor antagonist with high affinity. GR 203040 potently inhibits substance P binding to NK1 receptors (pKi = 10.1 to 10.5). Synonyms: (2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride. Grade: ≥98% by HPLC. CAS No. 168398-02-5. Molecular formula: C20H24N6O·2HCl. Mole weight: 437.37.
GR 231118
GR 231118. Group: Biochemicals. Grades: Purified. CAS No. 158859-98-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
GR 231118
GR 231118 is a potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1 receptors, respectively) and an NPY Y4 receptor agonist (pEC50 = 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors, respectively). GR 231118 inhibits food intake in rats in vivo. Synonyms: GR-231118; GR 231118; GR231118. Grade: >99%. CAS No. 158859-98-4. Molecular formula: C110H170N34O24. Mole weight: 2352.77.
GR24
(Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Strigolactone GR24. CAS No. 76974-79-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129038.
GR 46611 is a 5-HT1D receptor agonist that may be beneficial for the treatment of migraine. 5-HT1D acts on the central nervous system. Synonyms: GR 46611; GR46611; GR-46611; 3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)acrylamide. CAS No. 185259-85-2. Molecular formula: C23H27N3O2. Mole weight: 377.49.
GR 49336
A metabolite of Sumatriptan. Group: Biochemicals. Alternative Names: 5-[[ (Methylamino) sulfonyl]methyl]-. Grades: Highly Purified. CAS No. 103628-44-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
GR 49336
GR 49336. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[[(Methylamino)sulfonyl]methyl]-1H-indole-3-acetic Acid. Product Category: Heterocyclic Organic Compound. CAS No. 103628-44-0. Molecular formula: C12H14N2O4S. Mole weight: 282.32. Purity: 0.96. IUPACName: 2-[5-(methylsulfamoylmethyl)-1H-indol-3-yl]acetic acid. Canonical SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CC(=O)O. Density: 1.471g/cm³. Product ID: ACM103628440-1. Alfa Chemistry ISO 9001:2015 Certified.
GR5
GR5. Synonyms: (E)-3-(((4-methyl-5-methylene-2,5-dihydrofuran-2-yl)oxy)methylene)dihydrofuran-2(3H)-one. Grade: >95% by HPLC.
GR 55562 dihydrochloride
GR 55562 dihydrochloride is a selective and competitive 5-HT1B (5-HT1Dβ) silent antagonist (pKB values of 7.3 and 6.3 for human cloned 5-HT1B and 5-HT1D receptors, respectively). Synonyms: GR 55562 dihydrochloride; GR-55562; GR55562; GR 55562. 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride. Grade: ≥98% by HPLC. CAS No. 159533-25-2. Molecular formula: C23H25N3O2.2HCl. Mole weight: 448.39.
GR 55562 hydrochloride
GR 55562 hydrochloride is a selective 5-HT 1B receptor antagonist. GR 55562 hydrochloride can be used for the research of nerve disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172854-55-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W010869.
GR 64349
GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon). Synonyms: GR 64349; GR64349; GR-64349; LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2; [LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10); L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidi. Grade: >98%. CAS No. 137593-52-3. Molecular formula: C42H68N10O11S. Mole weight: 921.12.
GR 64349 TFA
GR 64349 is a potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon). Molecular formula: C44H69F3N10O13S. Mole weight: 1035.13.
GR 73632
GR 73632 is a potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). GR 73632 is able to be used in the treatment of asthma and gastrointestinal disorders. Synonyms: GR-73632; GR 73632; GR73632. Delta-Aminovaleryl-9-pro-10-meleu-substance P (7-10); Substance P (7-10), delta-aminovaleryl-pro(9)-N-meleu(10)-; Substance P (7-10), delta-aminovaleryl-prolyl(9)-N-methylleucine(10)-. CAS No. 133156-06-6. Molecular formula: C40H59N7O6S. Mole weight: 766.01.
GR-73632
GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist[1]. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals[2]. Uses: Scientific research. Group: Peptides. CAS No. 133156-06-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1192.
GR 79236
GR 79236, an effective Adenosine A1 receptor agonist, could probably be used as an anti-inflammatory agent. IC50: 3.1 nM(Ki). Uses: Gr 79236 is an effective adenosine a1 receptor agonist that could probably be used as an anti-inflammatory agent. Synonyms: GR79236; GR-79236; GR 79236. N-[(1S, trans)-2-Hydroxycyclopentyl]adenosine. Grade: 95%. CAS No. 124555-18-6. Molecular formula: C15H21N5O5. Mole weight: 351.36.
GR 82334 is a tachykinin NK1 receptor antagonist. Synonyms: GR-82334; GR 82334; GR82334; Physalaemin(1-11), D-pro(9)(spiro-gamma-lactam)leu(10)-trp(11)-; Physalemin, 9-deglycine-10-((5S)-6-oxo-L-alpha-(2-methylpropyl)-1,7-diazaspiro(4.4)nonane-7-acetic acid)-11-L-tryptophanamide-. Grade: >98%. CAS No. 129623-01-4. Molecular formula: C69H91N15O16. Mole weight: 1386.57.
GR 89696
GR 89696 is a highly selective κ2 opioid receptor agonist with potential to prevent pruritus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 126766-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-107747.
GR 89696 fumarate
GR 89696 fumarate is a potent and selective κ-opioid agonist (IC50 = 0.04 nM) displaying anti-nociceptive and neuroprotective activity. Synonyms: GR 89696 fumarate; GR 89696; GR89696; GR-89696. 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate. Grade: ≥99% by HPLC. CAS No. 126766-32-3. Molecular formula: C19H25Cl2N3O3.C4H4O4. Mole weight: 530.4.
GR 89696 fumarate
GR 89696 fumarate. Group: Biochemicals. Grades: Purified. CAS No. 126766-32-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
GR 94800 is a potent and selective tachykinin NK2 receptor antagonist (pKB = 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively). Synonyms: N-Benzoyl-L-alanyl-L-alanyl-D-tryptophyl-L-phenylalanyl-D-prolyl-L-prolyl-L-norleucinamide. Grade: >98%. CAS No. 141636-65-9. Molecular formula: C49H61N9O8. Mole weight: 904.08.
GR 94800 TFA
GR 94800 TFA is a potent and selective NK2 receptor peptide antagonist, with pKB values of 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively. Molecular formula: C51H62F3N9O10. Mole weight: 1018.08.
Gracillin
Gracillin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19083-00-2. Pack Sizes: 10mg. Molecular Formula: C45H72O17, Molecular Weight: 885.04. US Biological Life Sciences.
Worldwide
Gracillin
Gracillin is a steroidal saponin that can be extracted from the roots of the plant and has anti-tumor properties. Gracillin can induce cancer cell apoptosis and autophagy[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 19083-00-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0706.
GRA Ex-25
GRA Ex-25 is an orally active human glucagon receptor antagonist in a transgenic murine pharmacodynamic model, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively. GCGR has evolved as an attractive therapeutic target for the treatment of type II diabetes mellitus. Synonyms: 3-(4-((1-(4-(tert-butyl)cyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid; GRA Ex-25; GRA Ex 25; GRA Ex25; GRAEx-25; GRAEx 25; GRAEx25. CAS No. 307983-31-9. Molecular formula: C29H36F3N3O5. Mole weight: 563.61.
Grafoil Synthetic Thermal Graphite Film
Grafoil Synthetic Thermal Graphite Film. Group: Pyrolitic graphite.
Grahamimycin B
It is produced by the strain of Cytospora sp. W. F. P. L. 13A (ATCC20502). It has weak activity against gram-positive bacteria, negative bacteria, cyanobacteria and green algae. Synonyms: 1,7-Dioxacyclotetradec-3-ene-2,8,11-trione,9,12-dihydroxy-6,14-dimethyl-, (6R-(3E,6R*,9R*,12R*,14S*))-. CAS No. 75979-94-1. Molecular formula: C14H20O7. Mole weight: 300.30.
Grain Refiners
Grain Refiners. Products can be packaged according to specific requirements and as per international standards for export shipments.
Worldwide
Grains of Paradise P.E. 12.5% 6-paradol
Grains of Paradise P.E. 12.5% 6-paradol.
CA, FL & NJ
Gramicdin A
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Uses: Designed for use in research and industrial production. Product Category: Others. Appearance: Solid powder. CAS No. 11029-61-1. Molecular formula: C99H140N20O17. Mole weight: 1882.33. Purity: >98%. IUPACName: (R)-2-((2S,5R,8S,11R,14S,17R,20S,26S)-2-((1H-indol-3-yl)methyl)-17-isobutyl-5,8,11,26-tetraisopropyl-14,20-dimethyl-4,7,10,13,16,19,22,27,28-nonaoxo-3,6,9,12,15,18,21,24,25-nonaazaoctacosanamido)-N-((5S,8R,11S,14R,17S)-5,11-bis((1H-indol-3-yl)methyl)-1-hydroxy-18-(1H-indol-3-yl)-8,14-diisobutyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecan-17-yl)-4-methylpentanamide. Canonical SMILES: [H]C(N[C@H](C(NCC(N[C@@H](C)C(N[C@@H](C(N[C@@H](C)C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(N[C@@H](C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@@H](C(N[C@@H](CC5=CNC6=C5C=CC=C6)C(N[C@@H](C(N[C@@H](CC7=CNC8=C7C=CC=C8)C(NCCO)=O)=O)CC(C)C)=O)=O)CC(C)C)=O)=O)CC(C)C)=O)=O)C(C)C)=O)C(C)C)=O)C(C)C)=O)=O)CC(C)C)=O)=O)=O)C(C)C)=O. Product ID: ACM11029611-1. Alfa Chemistry ISO 9001:2015 Certified.
Gramicidin
Gramicidin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1405-97-6. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C99H14N20O17. US Biological Life Sciences.
Worldwide
Gramicidin
Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. Uses: Scientific research. Group: Peptides. CAS No. 1405-97-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P0163.
Gramicidin
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)international reference standards for antibiotics (who)pharmacopoeial standards. Alternative Names: Gramicidin, Gramoderm, Gramicidins.
Gramicidin
It is produced by the strain of Bacillus brevis. It is a family of linear pentadecapeptides isolated from bacillus brevis, and it is a complex of six closely related analogues A1, A2, B1, B2, C1 and C2 where A1 and A2 are the dominant components. It acts by forming channels in cell membranes causing ion leakage, and is an essential bioprobe for understanding the nature of the cell membranes. Synonyms: Gramicidina; Gramicidinum; garamicidin D; HCO-Val-Gly-D-Leu-Ala-D-Val-Val-D-Val-[Trp-D-Leu]3-Trp-NH2-CH2CH2OH. Grade: >95% by HPLC. CAS No. 1405-97-6. Molecular formula: C99H140N20O17. Mole weight: 1882.29.
Gramicidin
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C99H140N20O17. CAS No. 1405-97-6. Prepack ID 25163671-1g. Molecular Weight 1882.3. See USA prepack pricing.
Gramicidin
Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GRAMACIDIN D;GRAMICIDIN;GRAMICIDIN D;GRAMICIDIN D [DUBOS];gramicidin from bacillus brevis*(gramicidin D);Gramicidin micronized USP23;GramicidinN.F.Xiv;gramicidin from bacillus aneurinolyticus (bacillus brevis). Product Category: Inhibitors. Appearance: Solid. CAS No. 1405-97-6. Molecular formula: C99H140N20O17. Mole weight: 0. Purity: ≥98.0%. Product ID: ACM1405976. Alfa Chemistry ISO 9001:2015 Certified.
Gramicidin A
It is produced by the strain of Bacillus brevis. It mainly has anti-gram-positive bacterial activity, and also has effects on Naisseria. LD50 is 0.017 mg/kg (mice, intravenous injection). Synonyms: Valinegramicidin A; Valyl gramicidin A; 1-L-Valinegramicidin A; L-Tryptophanamide, N-formyl-L-valylglycyl-L-alanyl-D-leucyl-L-alanyl-D-valyl-L-valyl-D-valyl-L-tryptophyl-D-leucyl-L-tryptophyl-D-leucyl-L-tryptophyl-D-leucyl-N-(2-hydroxyethyl)-. Grade: ≥90%. CAS No. 11029-61-1. Molecular formula: C99H140N20O17. Mole weight: 1882.29.
Gramicidin A
Gramicidin A is an effective antibiotic against Gram positive organisms. Group: Biochemicals. Grades: Highly Purified. CAS No. 11029-61-1. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C99H140N20O17, Molecular Weight: 1882.29. US Biological Life Sciences.
Worldwide
Gramicidin A
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α ( HIF-1α ) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 11029-61-1. Pack Sizes: 5 mg. Product ID: HY-P2324.
Gramicidin B
Gramicidin B is a part of the collective Gramicidin D that is an antibiotic obtained from a soil microbe-Bacillus brevis. Molecular formula: C97H139N19O17. Mole weight: 1843.25.
Gramicidin c
Gramicidin c. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GRAMICIDIN C;GRAMICIDIN S;HCO-X-GLY-L-ALA-D-LEU-L-ALA-D-VAL-L-VAL-D-VAL-L-TRP-D-LEU-L-PHE-D-LEU-L-TRP-D-LEU-L-TRP-NHCH2CH2OH;Cyclo(L-Leu-D-Phe-L-Pro-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Val-L-Orn-);Cyclo(L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-);Gramicidin S1;Gramicidin S-A;Soviet Gramicidin C. CAS No. 113-73-5. Molecular formula: C60H92N12O10. Mole weight: 1141.45. Purity: 0.95. IUPACName: gramicidin S. Density: 1.24g/cm³. Product ID: ACM113735. Alfa Chemistry ISO 9001:2015 Certified.
Gramicidin C
Gramicidin C is a naturally occuring polypeptide antibiotic isolated from B. brevis var. G.B. Synonyms: Gramicidin C; NCGC00095992-01; Spectrum_000833; Spectrum2_001076; Spectrum3_001749; Spectrum4_000106; Spectrum5_001779; BSPBio_003458; KBioGR_000432; KBioSS_001313; SPECTRUM1500319; SPBio_001092; KBio2_001313; KBio2_003881; KBio2_006449; KBio3_002678; HMS2091H19; Pharmakon1600-01500319; CCG-39758; NSC757043; STK177209; AKOS005410749; NSC-757043; NCGC00095992-02; SBI-0051395.P003; FT-0775150; G05080; cyclo(leucylphenylalanylprolylvalylornithylleucylphenylalanylprolylvalylornithyl). Grade: >90% by HPLC. CAS No. 9062-61-7. Molecular formula: C60H92N12O10. Mole weight: 1141.4.
Gramicidin S
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Gramicidin soviet. CAS No. 113-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5712.
Gramicidin S
Gramicidin S is an anttiboitics. Gramicidin S reduces the cell number of planktonic cells within 20-40 min at a concentration of 40-80 μg/mL. Gramicidin S kills the cells of pre-grown biofilms at concentrations of 100-200 μg/mL, such that no re-growth is possible. The translocation of the peptide into the cell interior and its complexation with intracellular nucleotides, including the alarmon ppGpp, can explain its anti-biofilm effect. The successful treatment of persistently infected root canals of two volunteers confirms the high effectiveness of GS. The broad Gramicidin S activity towards resistant, biofilm-forming E. faecalis suggests its applications for approval in root canal medication. Uses: Designed for use in research and industrial production. Product Category: Others. Appearance: Solid powder. CAS No. 113-73-5. Molecular formula: C60H92N12O10. Mole weight: 1141.47. Purity: >98%. IUPACName: (6R,9S,12S,15S,17aS,23R,26S,29S,32S,34aS)-12,29-bis(3-aminopropyl)-6,23-dibenzyl-9,26-diisobutyl-15,32-diisopropyldocosahydro-1H,5H-dipyrrolo[1,2-a:1',2'-p][1,4,7,10,13,16,19,22,25,28]decaazacyclotriacontine-5,8,11,14,17,22,25,28,31,34(34aH)-decaone. Canonical SMILES: CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C. Product ID: ACM113735-1. Alfa Chemistry ISO 9001:2015 Certified.
Gramicidin S
Gramicidin S is an antibiotic produced by the strain of Bacillus brevis. It is effective against some gram-positive and gram-negative bacteria as well as some fungi. Uses: For research use only. Synonyms: Gramicin S-A; Gramicin S 1; Cyclo(L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl); Gramacidine S; Gramicidina S; Gramicidinum S. Grade: >95%. CAS No. 113-73-5. Molecular formula: C60H92N12O10. Mole weight: 1141.46.
Gramicidin S dihydrochloride
It is produced by the strain of Bacillus brevis. It mainly has anti-gram-positive bacterial activity. Synonyms: Gramicidin S 2HCl. CAS No. 15207-30-4. Molecular formula: C60H92N12O10.2HCl. Mole weight: 1214.36.