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| Product | Description | |
|---|---|---|
| Griseolutein B | It is produced by the strain of Streptomyces griseoluteus. Griseolutein A and Griseolutein B have similar activitiy against gram-positive and negative bacteria, and Griseolutein B also inhibits rickettsia, trichomonas vaginalis and Ehrlichite ascites cancer. Synonyms: 6-[(1,2-Dihydroxyethoxy)methyl]-9-methoxy-1-phenazinecarboxylic acid. Grades: >98%. CAS No. 2072-68-6. Molecular formula: C17H16N2O6. Mole weight: 344.32. |  |
| Griseorhodin A | It is produced by the strain of Streptomyces californicus JA-2640 and Str. griseus (FCRC-57). It is a quinone antibiotic. It mainly has anti-gram-positive bacterial activity. Synonyms: 1'a,9'b-Dihydro-3,4,4',9-tetrahydroxy-7-methoxy-7'-methylspiro[naphtho[2,3-b]furan-2(3H),2'(5'H)-oxireno[d]benzo[1,2-b:5,4-c']dipyran]-5,5',8-trione. Grades: 99%. CAS No. 11048-91-2. Molecular formula: C25H16O12. Mole weight: 508.39. | |
| Griseorhodin C | It is produced by the strain of Streptomyces californicus JA-2640 and Str. griseus (FCRC-57). It is a quinone antibiotic. It mainly has anti-gram-positive bacteria and negative bacteria (individual) activity. Molecular formula: C25H18O13. Mole weight: 526.40. | |
| Griseorhodin G | It is produced by the strain of Streptomyces californicus JA-2640 and Str. griseus (FCRC-57). It is a quinone antibiotic. It has antitumor activity. Synonyms: NSC289645; FCRC57-G; FCRC-57-G. Molecular formula: C25H18O12. Mole weight: 510.40. | |
| Griseoviridin | It is produced by the strain of Streptomyces griseoviridus. It is an Estopeptide antibiotic. It has anti-gram positive bacteria, negative bacteria (individual) activity. Synonyms: (-)-Griseoviridin; 20-O-Demethylgriseoviridin C; [1S-(1R*,9S*,11R*,12E,14E,19Z,22S*)]-9,11-Dihydroxy-22-methyl-6,23-dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentaene-3,18,24-trione. Grades: 95%. CAS No. 53216-90-3. Molecular formula: C22H27N3O7S. Mole weight: 477.53. | |
| Griseoxanthone B | Synonyms: 9H-Xanthen-9-one, 4,7-dihydroxy-2-methoxy-1,5-dimethyl-. CAS No. 2305686-01-3. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Griseusin A | It is produced by the strain of Streptomyces griseus. It is a quinone antibiotic. It mainly has anti-gram-positive bacterial activity. Synonyms: (-)-Griseusin A; (3aR,5R)-3'alpha,7-Dihydroxy-4'alpha-acetoxy-6'beta-methyl-3',3aalpha,4',5',6',11balpha-hexahydrospiro[2H-furo[3,2-b]naphtho[2,3-d]pyran-5(3H),2'-[2H]pyran]-2,6,11-trione; (5R,3aR,11bR)-4'α-Acetyloxy-3',3a,4',5',6',11b-hexahydro-3'α,7-dihydroxy-6'β-methylspiro[5H-furo[3,2-b]naphtho[2,3-d]pyran-5,2'-[2H]pyran]-2,6,11(3H)-trione. CAS No. 59554-11-9. Molecular formula: C22H20O10. Mole weight: 444.39. | |
| Griseusin B | It is produced by the strain of Streptomyces griseus. It is a quinone antibiotic. It mainly has anti-gram-positive bacterial activity. Synonyms: [(1R,3S,3'S,4'R,6'R)-4'-acetoxy-3',9-dihydroxy-6'-methyl-5,10-dioxo-3,3',4,4',5,5',6',10-octahydrospiro[naphtho[2,3-c]pyran-1,2'-pyran]-3-yl]acetic acid; (1R)-4'α-Acetoxy-3,3',4,4',5,5',6',10-octahydro-3'α,9-dihydroxy-6'β-methyl-5,10-dioxospiro[1H-naphtho[2,3-c]pyran-1,2'-[2H]pyran]-3α-acetic acid. CAS No. 59554-12-0. Molecular formula: C22H22O10. Mole weight: 446.40. | |
| Grisorixin | It is a polyether antibiotic produced by the strain of Streptomyces griseus. It has anti-bacterial, filamentous and yeast fungal activities (0.1-200 μg/mL), can prevent the infection of spores of legume crops (0.01% solution), has plant toxicity (0.02% solution), and can kill potato beetles, aphids and mites (0.05%-0.1% solution) and inhibits HeLa cells. Synonyms: 30-Deoxynigericin; Nigericin, 30-deoxy-; Grisorixine; Desoxynigericin; Antibiotic K 358; K 358. CAS No. 31357-58-1. Molecular formula: C40H68O10. Mole weight: 708.96. | |
| grixazone synthase | A type 3 multi copper protein. The enzyme, isolated from the bacterium Streptomyces griseus, catalyses an 8 electron oxidation. Activation of the enzyme requires a copper chaperone (GriE). It also acts on 3-amino-4-hydroxybenzaldehyde, giving grixazone A. The second aldehyde group is presumably lost as formate. The enzyme also catalyses the reaction of EC 1.10.3.4 o-aminophenol oxidase. Group: Enzymes. Synonyms: GriF. Enzyme Commission Number: EC 1.10.3.15. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0481; grixazone synthase; EC 1.10.3.15; GriF. Cat No: EXWM-0481. |  |
| GRK2i | GRK2i. Group: Biochemicals. Grades: Purified. CAS No. 148505-03-7. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| GRK2i | GRK2i is a polypeptide inhibitor of GRK2 that specifically inhibits Gβγ activation of GRK2. GRK2i corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist. Grades: >98%. CAS No. 148505-03-7. Molecular formula: C153H256N50O41S. Mole weight: 3484.08. | |
| GRK2 Inhibitor 1 | GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24269-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123538. |  |
| GRL-117C | GRL-117C is a CCR5 inhibitor that can inhibit the replication of wild-type R5-HIV-1. Synonyms: (4-Nitrophenyl)Methyl N-Allyl-N-[8-[4-[Benzenesulfonyl(Methyl)Amino]-3-Methyl-3-Phenyl-Butyl]-8-Azabicyclo[3.2.1]Octan-3-Yl]Carbamate; GRL117C; GRL 117C. Molecular formula: C36H44N4O6S. Mole weight: 660.8. | |
| Groenlandicine | Groenlandicine, a botanical-derived constituent, exhibits profound implications for biomedical applications of studying an array of afflictions, encompassing neoplastic disorders and cardiovascular impairments. Synonyms: 11,12-Dihydro-8-methoxy-9-hydroxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium; 11,12-Dihydro-9-hydroxy-8-methoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium; Groenlandicine; Tetrahydricheilanthifolinium; Tetrahydrocheilanthifoline; Tetradehydrocheilanthifoline. Grades: >98%. CAS No. 38691-95-1. Molecular formula: C19H16NO4+. Mole weight: 322.33464. | |
| Gromwell Root Extract | Gromwell Root Extract. Applications: Anti-tumor effects,main role of the cardiovascular system, mainly used for hepatitis, dermatitis and baby, women vaginitis, cervicitis, and other drugs. Group: Others. Synonyms: Gromwell Root Extract; Lithospermum erythrorhizon. Purity: 30% Shikonin by UV. Appearance: Deep purple-red stiffen Cream. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Lithospermum erythrorhizon. Gromwell Root Extract; Lithospermum erythrorhizon; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-179. | |
| Grosvenorine | Grosvenorine. Group: Biochemicals. Grades: Plant Grade. CAS No. 156980-60-8. Pack Sizes: 10mg. Molecular Formula: C33H40O19, Molecular Weight: 740.66. US Biological Life Sciences. | Worldwide |
| Grosvenorine | Grosvenorine is extracted from roots of the fruits of Siraitia grosuenorii. It has free radical scavenging activity. Synonyms: Grosvenorin. Grades: >98%. CAS No. 156980-60-8. Molecular formula: C33H40O19. Mole weight: 740.7. | |
| Grosvenorine | Grosvenorine is the major flavonoid compound of the fruits of Siraitia grosvenorii. Grosvenorine exhibits good antibacterial and antioxidant activities. Group: Inhibitors. Alternative Names: Momordica grosvenori lutein. CAS No. 156980-60-8. Molecular formula: C33H40O19. Mole weight: 740.66. Appearance: Powder. Purity: 0.98. IUPACName: 7-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one. Canonical SMILES: C[C@H]1[C@@H] ([C@H] ([C@H] ([C@@H] (O1)OC2=C (OC3=CC (=CC (=C3C2=O)O)O[C@H]4[C@@H] ([C@@H] ([C@H] ([C@@H] (O4)C)O)O)O[C@H]5[C@@H] ([C@H] ([C@@H] ([C@H] (O5)CO)O)O)O)C6=CC=C (C=C6)O)O)O)O. Density: 1.74±0.1 g/ml. Catalog: ACM156980608. |  |
| Growth hormone,human | Heterocyclic Organic Compound. Alternative Names: cb311; crecormon; humatrope; ly137998; norditropin; sj0011; OVINE SOMATOTROPIN;SOMATOTROPIN. CAS No. 12629-01-5. Molecular formula: C990H1529N263O299S7. Mole weight: 22124.12. Appearance: lyophilized powder. Catalog: ACM12629015. | |
| Growth Hormone, Human | Human growth hormone is a single-chain polypeptide hormone required for the growth of tissues. Synonyms: cb311; crecormon; humatrope; ly137998; norditropin; sj0011; OVINE SOMATOTROPIN; SOMATOTROPIN. Grades: 95%. CAS No. 12629-01-5. Molecular formula: C990H1529N263O299S7. Mole weight: 22124.12. | |
| GROWTH HORMONE RELEASING FACTOR 1-29*AMI DE, BOVINE | Heterocyclic Organic Compound. CAS No. 112898-04-1. Molecular formula: NULL. Mole weight: 3384.91. Purity: 0.96. Canonical SMILES: CCC (C)C (C (=O)NC (CC1=CC=CC=C1)C (=O)NC (C (C)O)C (=O)NC (CC (=O)N)C (=O)NC (CO)C (=O)NC (CC2=CC=C (C=C2)O)C (=O)NC (CCCNC (=N)N)C (=O)NC (CCCCN)C (=O)NC (C (C)C)C (=O)NC (CC (C)C)C (=O)NCC (=O)NC (CCC (=O)N)C (=O)NC (CC (C)C)C (=O)NC (CO)C (=O)NC (C)C (=O)NC (CCCNC (=N)N)C (=O)NC (CCCCN)C (=O)NC (CC (C)C)C (=O)NC (CC (C)C)C (=O)NC (CCC (=O)N)C (=O)NC (CC (=O)O)C (=O)NC (C (C)CC)C (=O)NC (CCSC)C (=O)NC (CC (=O)N)C (=O)NC (CCCNC (=N)N)C (=O)N)NC (=O)C (C)NC (=O)C (CC (=O)O)NC (=O)C (C)NC (=O)C (CC3=CC=C (C=C3)O)N. Catalog: ACM112898041. | |
| GRPP (human) | GRPP (human) is a synthetic analogue of a cleavage product resulting from proglucagon processing in pancreatic α- and intestinal L-cells. Synonyms: Preproglucagon (21-50) (human); H-Arg-Ser-Leu-Gln-Asp-Thr-Glu-Glu-Lys-Ser-Arg-Ser-Phe-Ser-Ala-Ser-Gln-Ala-Asp-Pro-Leu-Ser-Asp-Pro-Asp-Gln-Met-Asn-Glu-Asp-OH; glicentin-related polypeptide (human); L-arginyl-L-seryl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-seryl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-alanyl-L-seryl-L-glutaminyl-L-alanyl-L-alpha-aspartyl-L-prolyl-L-leucyl-L-seryl-L-alpha-aspartyl-L-prolyl-L-alpha-aspartyl-L-glutaminyl-L-methionyl-L-asparagyl-L-alpha-glutamyl-L-aspartic acid. Grades: ≥95%. CAS No. 1132745-52-8. Molecular formula: C136H215N41O58S. Mole weight: 3384.47. | |
| GRP (porcine) | GRP (porcine) is a mammalian bombesin-like peptide neurotransmitter that acts as an agonist for the gastrin-releasing peptide receptor (GRPR). It was shown to activate GABAergic interneurons in the amygdala resulting in an increase in GABA release and fear suppression in mice in vivo. Synonyms: Gastrin Releasing Peptide porcine. CAS No. 74815-57-9. Molecular formula: C126H198N38O31S2. Mole weight: 2805.31. | |
| GRPSp | GRPSp was found in the mud crab Scylla paramamosain. It is active against Gram-positive A. viridans, M. Luteus, (MIC=6-25 μg/ml). Grades: >97% by HPLC. | |
| Grubbs Catalyst, 2nd gen | 100mg Pack Size. Group: Catalysts. Formula: C46H65Cl2N2PRu. CAS No. 246047-72-3. Prepack ID 60505776-100mg. Molecular Weight 848.97. See USA prepack pricing. |  |
| Grubbs Catalyst, 2ndGeneration | Synonyms: (1, 3-Bis (2, 4, 6-trimethylphenyl)-2-imidazolidinylidene)dichloro (phenylmethylene) (tricyclohexylphosphine)ruthenium, Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichlo. Grades: 98%. CAS No. 246047-72-3. Molecular formula: C46H65Cl2N2PRu. Mole weight: 848.97. | |
| Grubbs Catalyst, 2nd Generation | Grubbs Catalyst, 2nd Generation is a ruthenium-based olefin metathesis catalyst. Group: Biochemicals. Grades: Highly Purified. CAS No. 246047-72-3. Pack Sizes: 250mg, 500 mg. Molecular Formula: C46H65Cl2N2PRu. US Biological Life Sciences. | Worldwide |
| Grubbs catalyst I | Grubbs catalyst I. Group: Biochemicals. Alternative Names: Bis- (tri cyclohexylphosphino) -benzylide ne ruthenium dichloride. Grades: Highly Purified. CAS No. 172222-30-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C44H74Cl2P2Ru. US Biological Life Sciences. | Worldwide |
| Grubbs catalyst II | Grubbs catalyst II. Group: Biochemicals. Alternative Names: [1, 3-Bis- (2, 4, 6-tri methyl phenyl) -2-imidazolidinylide ne ] -dichloro- (phenyl methyl ene ) (tri cyclohexylphosphine) -ruthenium . Grades: Highly Purified. CAS No. 246047-72-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C46H65Cl2N2PRu. US Biological Life Sciences. | Worldwide |
| GS-0573 | GS 0573 is an antiviral compound that has been studied for potential treatment of Feline herpesvirus 1 (FHV-1). Group: Others. Alternative Names: GS 0573; GS0573; GS-0573. CAS No. 113852-41-8. Molecular formula: C8H13N6O4P. Mole weight: 288.2. Appearance: Solid powder. Purity: >98%. IUPACName: ((2-(2,6-diamino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid. Canonical SMILES: O=P(O)(O)COCCN1C2=NC(N)=NC(N)=C2N=C1. Catalog: ACM113852418. | |
| GS 143 | GS 143 is a β-TrCP1 ligase inhibitor. GS 143 exhibits inhibitory effects on IκBα ubiquitination (IC50 = 5.2 μM), LPS-induced expression of inflammatory cytokines in human myelomonocytic cells, antigen-induced NFκB expression, inflammation and mucus production in airways of OVA-sensitized mice. Synonyms: GS-143; GS 143; GS143; 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 916232-21-8. Molecular formula: C28H19FN2O4. Mole weight: 466.46. | |
| GS-283 | GS-283, an isoquinolin derivative, has been found to be histamine receptor and muscarinic receptor blocker. Synonyms: GS 283; GS-283; GS283; 6,7-Isoquinolinediol, 3,4-dihydro-1-((4-methoxyphenyl)methyl)-; 7-hydroxy-1-[(4-methoxyphenyl)methyl]-3,4-dihydro-2H-isoquinolin-6-one. Grades: 98%. CAS No. 149440-36-8. Molecular formula: C17H17NO3. Mole weight: 283.33. | |
| GS 389 | GS 389 is a novel tetrahydroisoquinoline analog which significantly increased cGMP levels in the rat aorta and inhibited cGMP phosphodiesterase from the rabbit brain. Uses: A novel tetrahydroisoquinoline analog. Synonyms: GS 389; GS-389; GS389. 6,7-dimethoxy-1-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline. Grades: ≥98%. CAS No. 41498-37-7. Molecular formula: C19H23NO3. Mole weight: 313.39. | |
| GS39783 | GS39783 is a positive allosteric modulator (PAM) of GABA B R. Positive modulation of the GABA B R can be used for the research of Nicotine addiction [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39069-52-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103475. | |
| GS 39783 | GS 39783 is an allosteric positive modulator of GABAB receptors, decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines. Uses: Positive allosteric modulator of gabab receptor function. Synonyms: GS39783; GS-39783; GS 39783; N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine;4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine. Grades: ≥98%. CAS No. 39069-52-8. Molecular formula: C15H23N5O2S. Mole weight: 337.44. | |
| GS 39783 | GS 39783. Group: Biochemicals. Alternative Names: N4,N6-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine; N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine. Grades: Highly Purified. CAS No. 39069-52-8. Pack Sizes: 10mg. Molecular Formula: C15H23N5O2S, Molecular Weight: 337.44. US Biological Life Sciences. | Worldwide |
| GS-441524 | GS-441524, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC 50 of 0.78 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1191237-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103586. | |
| GS-441524 | GS-441524 is an analog nucleotide inhibitor against feline infectious peritonitis virus (FIPV). EC50 is 0.78?uM. GS-441524 is also a metabolite and intermediate of Remdesivir. Synonyms: (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile; EVO984; EVO 984; EVO-984; GS441524; GS 441524; GS-441524; CHEMBL2016757; SCHEMBL10120689; EX-A3056; Remdesivir-metabolite; GS-5734-metabolite. Grades: 97%. CAS No. 1191237-69-0. Molecular formula: C12H13N5O4. Mole weight: 291.26. | |
| GS 6201 | GS 6201. Group: Biochemicals. Grades: Purified. CAS No. 752222-83-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GS 6201 | GS 6201 is a selective A2B antagonist. Synonyms: CVT6883; CVT 6883; CVT-6883; GS6201; GS-6201; GS 6201; 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione. CAS No. 752222-83-6. Molecular formula: C21H21F3N6O2. Mole weight: 446.43. | |
| GS-7340 fumarate | Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil fumarate to elvitegravir / cobicistat / emtricitabine / tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. Synonyms: GS-7340 fumarate; GS 7340 fumarate; GS7340 fumarate; (S)-isopropyl 2- ( ( (S)- ( ( ( (R)-1- (6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (phenoxy)phosphoryl)amino)propanoate fumarate; TAF; GS734; GS-734; GS 7340; Tenofovir alafenamide fumarate; trade name: Genvoya. Grades: >98%. CAS No. 379270-38-9. Molecular formula: C25H33N6O9P. Mole weight: 592.54. | |
| GS-9219 | GS-9219 is a prodrug of the acyclic nucleoside phosphonate analogue 9-(2-phosphonylmethoxyethyl)guanine (PMEG) with potential antineoplastic activity. Formulated to selectively accumulate in lymphocytes, nucleotide analogue GS 9219 is converted to its active metabolite, PMEG diphosphate (PMEGpp), via enzymatic hydrolysis, deamination, and phosphorylation; subsequently, PMEGpp is incorporated into nascent DNA chains by DNA polymerases, which may result in the termination of DNA synthesis, S-phase cell cycle arrest, and the induction of apoptosis in susceptible lymphoma cell populations. Synonyms: GS 9219; GS9219. CAS No. 859209-74-8. Molecular formula: C21H35N8O6P. Mole weight: 526.53. | |
| GS 9620 | GS 9620 is a potent and oral agonist of TLR7. Uses: Antiviral agents. Synonyms: 4-amino-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one; GS-9620; GS9620; Vesatolimod. Grades: 99.90%. CAS No. 1228585-88-3. Molecular formula: C22H30N6O2. Mole weight: 410.51. | |
| GS9667 | GS9667 is a new selective, partial agonist of the A(1) adenosine receptor (AR). It may be an effective therapy for Type 2 diabetes and dyslipidemia via lowering of free fatty acids (FFA). It was developed by Gilead and was in clinic phase 1 trials without progress. Uses: Gs966 may be an effective therapy for type 2 diabetes and dyslipidemia via lowering of free fatty acids (ffa). Synonyms: GS-9667; GS 9667; CVT-3619; CVT 3619; CVT3619. Grades: 98%. CAS No. 618380-90-8. Molecular formula: C21H24FN5O4S. Mole weight: 461.51. | |
| GS-9667 | GS-9667 (CVT 3619), a novel N 6 -5'-substituted adenosine analog, is a selective, partial agonist of the A 1 adenosine receptor (A 1 AdoR). GS-9667 binds to adipocyte membranes with high (K H =14 nM) and low (K L =5.4 μM) affinities. GS-9667 reduces cyclic AMP content and release of nonesterified fatty acids from epididymal adipocytes with IC 50 values of 6 nM and 44 nM, respectively. GS-9667 inhibits lipolysis and has the potential for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT 3619. CAS No. 618380-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19842. | |
| GS967 | GS967, also known as GS-458967, is a highly selective late sodium channel current blocker. The selective inhibition of late INa with GS967 can exert antiarrhythmic effects by suppressing EAD- and DAD-mediated extrasystolic activity in PFs and PV and SVC sleeve preparations. Synonyms: GS967; GS-967; GS 967; GS458967; GS 458967; GS-458967. Grades: 98%. CAS No. 1262618-39-2. Molecular formula: C14H7F6N3O. Mole weight: 347.22. | |
| GS-9822 | GS-9822 is one of novel non-catalytic site integrase inhibitors (NCINIs), which is a potential class of antiretroviral (ARV) agents. GS-9822 exhibits a potent effect against the T174I mutant (EC50: 3.0 ± 0.9 nM) and IN polymorphic variants (fold shift: 0.4 to 1.3). Studies showed that it has excellent pharmacokinetic properties and metabolic stability. Uses: Antiretroviral (arv) agent. Synonyms: GS 9822; GS9822. CAS No. 2219362-41-9. Molecular formula: C36H39ClN4O4S. Mole weight: 659.24. | |
| GSA 10 | GSA 10 is a quinolinecarboxamide derivative that acts as a Smoothened/Smo receptor agonist (EC50 = 1.2 μM). GSA 10 can promote differentiation of multipotent mesenchymal progenitor cells into osteoblasts. Uses: Smoothened (smo) receptor agonist. Synonyms: GSA-10; propyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate. Grades: >98%. CAS No. 300833-95-8. Molecular formula: C26H30N2O5. Mole weight: 450.53. | |
| GSA 10 | GSA 10. Group: Biochemicals. Grades: Purified. CAS No. 300833-95-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Gsa I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 70°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme about 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CCCAG↑C G↓GGTCG. Activity: 10000-20000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Geobacillus stearothermophilus Y. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1115RE. | |
| GS-CA-1 | GS-CA-1 is a novel HIV capsid inhibitor developed by Gilead, which is a promisingly long-acting antiretroviral (ARV) agent. The preclinical study showed that GS-CA-1 could inhibit HIV-1 replication in human peripheral blood mononuclear cells (PBMCs) (EC50 = 140 pM). Uses: Long-acting antiretroviral (arv) agent. Synonyms: GS CA 1. Grades: 99.94%. CAS No. 2189684-45-3. Molecular formula: C41H36ClF8N7O5S2. Mole weight: 958.34. | |
| g-Secretase Inhibitor XX ( (S, S) -2-[2- (3, 5-Difluorophenyl) acetylamino]-N- (5-methyl-6-oxo-6, 7-dihydro-5H-dibenzo[b, d]azepin-7-yl) propionamide, DBZ, Dibenzazepine) | A cell-permeable dibenzazepine (dbz) compound that acts as a potent y-secretase inhibitor and significantly lowers both brain and plasma AB40 levels by ~72% in Tg2576 mutant APP transgenic mouse model (100umol/kg, b.i.d). Induces a heterogeneous reorganization of the crypt structural-proliferative units in the intestinal tract and of the stem cell niche in the colon. Also potently inhibits Notch processing (IC50=1.7nM in SupT1 cells) and induces conversion of proliferative crypt cells to post-mitotic goblet cells in both the C57BL/6 and ApcMin mouse models (10umol/kg, i.p). CAS Number:209984-56-5. Group: Biochemicals. Grades: Highly Purified. CAS No. 209984-56-5. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| GSH-CdTe, | GSH-CdTe. Group: Quantum dots. |  |
| GSI-136 | GSI-136 is an amyloid precursor protein secretase inhibitor. Uses: γ-secretase inhibitor. Synonyms: GSI-136; GSI 136; GSI136. (S)-5-chloro-N-(3-ethyl-1-hydroxypentan-2-yl)thiophene-2-sulfonamide. Grades: ≥98%. CAS No. 443989-01-3. Molecular formula: C11H18ClNO3S2. Mole weight: 311.83. | |
| GSI-953 | Begacestat (GSI-953) is a selective β-secretase inhibitor that selectively inhibits cleavage of APP over Notch. GSI-953 is used for treating diseases such as cancer in relation to prevention of intestinal secretory metaplasia. Group: Biochemicals. Alternative Names: 5-Chloro-N-[ (1S) -3, 3, 3-trifluoro-1- (hydroxymethyl) -2- (trifluoromethyl) propyl]-2-thiophenesulfonamide; Begacestat; GSI 953. Grades: Highly Purified. CAS No. 769169-27-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GSK0660 | GSK0660 is a selective PPARδ antagonist. GSK0660 blocks the effect of TNFα on the expressions of cytokines involved in leukocyte recruitment, including CCL8, CCL17, and CXCL10, and it may block TNFα-induced retinal leukostasis. Synonyms: GSK0660; GSK-0660; GSK 0660. Grades: 96%. CAS No. 1014691-61-2. Molecular formula: C19H18N2O5S2. Mole weight: 418.48. | |
| GSK 0660 | GSK 0660. Group: Biochemicals. Grades: Purified. CAS No. 1014691-61-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GSK-1014802 hydrochloride | GSK-1014802 hydrochloride is the hydrochloride form of GSK-1014802, which is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. It acts as a selective, small-molecule, state-dependent Nav1.7 voltage-gated sodium channel blocker. It received orphan-drug designation from the US Food and Drug Administration in July 2013. It was developed by Convergence Pharmaceuticals. It is currently in phase II studies in bipolar depression. Uses: Gsk-1014802 hydrochloride is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. it received orphan-drug designation from the us food and drug administration in july 2013. Synonyms: GSK-1014802 hydrochloride; GSK 1014802 hydrochloride; GSK1014802 hydrochloride; (2S,5R)-5-(4-((2-Fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide hydrochloride;(5R)-5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-L-prolinamide hydrochlorideCNV1014802 hydrochloride;CNV-1014802 hydrochloride;Raxatrigine hydrochloride. Grades: >98%. CAS No. 934240-31-0. Molecular formula: C18H20ClFN2O2. Mole weight: 350.82. | |
| GSK1016790A | GSK1016790A is a novel and potent TRPV4 channel agonist. The TRPV4 (transient receptor potential vanilloid 4) member of the TRP superfamily has been implicated in numerous physiological processes. GSK1016790A elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300 fold more potent than 4a-PDD. Applications: A novel and potent trpv4 channel agonist. Group: Coenzymes. Synonyms: (N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide. CAS No. 942206-85-1. Purity: ≥98%. Mole weight: 655.61. Form: Solid. (N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide; GSK1016790A; 942206-85-1. Cat No: COEC-115. | |
| GSK1016790A | GSK1016790A is a novel and potent transient receptor potential vanilloid 4 (TRPV4) agonist. It has been used to demonstrate a role for TRPV4 in regulating urinary bladder activity and endothelial control of vascular tone. It elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells with EC50 values of 18 and 2.1 nM, respectively. It also evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM, which is 300 fold more potent than 4a-PDD. It was developed by GlaxoSmithKline. Uses: Gsk1016790a regulats urinary bladder activity and endothelial control of vascular tone. Synonyms: GSK1016790A; GSK-1016790A; GSK 1016790A. N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide. Grades: >98 %. CAS No. 942206-85-1. Molecular formula: C28H32Cl2N4O6S2. Mole weight: 655.61. | |
| GSK1059615 | GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Synonyms: GSK-1059615; GSK 1059615; GSK1059615. Grades: >98%. CAS No. 958852-01-2. Molecular formula: C18H11N3O2S. Mole weight: 333.36. | |
| GSK1059615 | GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC 50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 958852-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12036. | |
| GSK 1059615 | GSK 1059615 is a potent inhibitor of PI 3-kinase α (PI3Kα). GSK 1059615 inhibits proliferation in BT474 cells and attenuates MAPK signaling. Group: Biochemicals. Alternative Names: (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione. Grades: Highly Purified. CAS No. 958852-01-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GSK-1070806 | GSK-1070806 is a CHO-expressed humanized antibody that targets IL-18. GSK-1070806 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 147.38 kDa. The isotype control for GSK-1070806 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Aletekitug. CAS No. 2923284-67-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990591. | |
| GSK1070916 | GSK1070916. Uses: For analytical and research use. Group: Impurity standards. CAS No. 942918-07-2. Molecular Formula: C30H33N7O. Mole Weight: 507.63. Catalog: APB942918072. |  |
| GSK-1070916A | GSK-1070916A is an ATP-competitive inhibitor of the serine/threonine kinases Aurora B and C with potential antineoplastic activity. Aurora B/C kinase inhibitor GSK1070916A binds to and inhibits the activity of Aurora kinases B and C, which may result in inhibition of cellular division and a decrease in the proliferation of tumor cells that overexpress the Aurora kinases B and C. Aurora kinases play essential roles in mitotic checkpoint control during mitosis, and are overexpressed by a wide variety of cancer cell types. Synonyms: GSK 1070916; GSK-1070916; GSK 1070916; GSK1070916A; GSK-1070916A; GSK 1070916A; NMI-900; NMI 900; NMI900. CAS No. 942918-07-2. Molecular formula: C30H33N7O. Mole weight: 507.63. | |
| GSK-1071306 | GSK-1071306 is one of the metabolites of pazopanib which is a inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity as a approved drug. Synonyms: GSK-1071306; GSK1071306; GSK 1071306; Pazopanib metabolite M27;5-((4-((2,3-dimethyl-2H-indazol-6-yl)amino)-2-pyrimidinyl)amino)-2-methyl-Benzenesulfonamide. Grades: 98%. CAS No. 1252927-47-1. Molecular formula: C20H21N7O2S. Mole weight: 423.49. | |
| GSK-114 | GSK-114 is a selective TNNI3 Interacting Kinase (TNNI3K) inhibitor with IC50 of 25nM. GSK-114 shows significant bias for TNNI3K over B-Raf, exceptional broad spectrum kinase selectivity and adequate oral exposure to enable its use in cellular and in vivo studies. Ralated studies has shown that TNNI3 Interacting Kinase has been linked to the progression of dilated cardiomyopathy, cardiac hypertrophy, and ischemia/reperfusion injury using models that employ TNNI3K overexpressing or TNNI3K knockout animals. Synonyms: GSK-114; GSK 114; GSK114; 3-((6,7-dimethoxyquinazolin-4-yl)amino)-4-(dimethylamino)-N-methylbenzenesulfonamide; 1301760-19-9 (2HCl). Grades: 98%. CAS No. 1301761-96-5. Molecular formula: C19H23N5O4S. Mole weight: 417.48. | |
| GSK-114 2Hcl | GSK-114 is a potent and selective TNNI3K inhibitor (TNNI3 IC50 = 25nM; B-RafV600E IC50 = 1000 nM). GSK-114 displays significant bias (40-fold) for TNNI3K over B-Raf, exceptional broad spectrum kinase selectivity, and adequate oral exposure to enable its use in cellular and in vivo studies. Synonyms: GSK-114 2Hcl; GSK114 2Hcl; GSK 114 2Hcl. CAS No. 1301760-19-9. Molecular formula: C19H23N5O4S.2HCl. Mole weight: 495.484. | |
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