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| Product | Description | |
|---|---|---|
| GPR109b Agonist - CAS 306935-41-1 | The GPR109b Agonist, also referenced under CAS 306935-41-1, controls the biological activity of GPR109b. This small molecule/inhibitor is primarily used for Activators/Inducers applications. Group: Fluorescence/luminescence spectroscopy. |  |
| GPR119 Agonist, AS1269574 (G-Protein Coupled Receptor 119 Agonist, 2-((2-(4-Bromophenyl)-6-methylpyrimidin-4-yl)amino)ethanol, GPCR2 Agonist, MGC119957 Agonist, SNORF25 Agonist) | A pyrimidine compound that acts as an effective GPR119 agonist (EC50=2.5uM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward B-adrenergic or GLP-1 receptors. Shown to enhance 16.8mM glucose-induced insulin secretion from murine MIN-6 B-cells (mU/20 min=0.44 and 0.22, respectively, with or without 10uM AS1269574) in vitro and improve glucose tolerance in normal mice (100mg/kg; p.o.) without any significant hypoglycemic effect in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 330981-72-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| GPR120 Agonist 1 | GPR120 Agonist 1 is a potent and selective GPR120 agonist with promising antidiabetic effects and good safety. Synonyms: GPR120 agonist 4x; 3-(4-((3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl)methoxy)-3,5-difluorophenyl)propanoic acid; Benzenepropanoic acid, 4-[[3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)-4-isothiazolyl]methoxy]-3,5-difluoro-. Grade: ≥95%. CAS No. 1628448-77-0. Molecular formula: C20H12ClF6NO3S. Mole weight: 495.82. |  |
| GPR120-IN-1 | GPR120-IN-1, a cell-permeable azaspiroundecanyl acetic acid compound, is an orally available, selective agonist of GPR120 (EC50 = ~0.35 μM) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1). Synonyms: 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid; GPR120 Compound A; MDK77754; MDK-77754; MDK 77754; GPR120 cpdA. CAS No. 1599477-75-4. Molecular formula: C19H23ClF3NO3. Mole weight: 405.84. | |
| GPR120 modulator 1 | GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 1; 1050506-75-6; 2-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenoxy]acetic acidAcetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]-GPR120-modulator-1. Grade: >98%. CAS No. 1050506-75-6. Molecular formula: C19H16ClNO4S. Mole weight: 389.85. | |
| GPR120 modulator 2 | GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 2; 1050506-87-0; 3-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenyl]propanoic acidBenzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl-3-(4-{[4-(2-CHLOROPHENYL)-1,3-THIAZOL-2-YL]METHOXY}-2-METHYLPHENYL)PROPANOIC ACID. Grade: >98%. CAS No. 1050506-87-0. Molecular formula: C20H18ClNO3S. Mole weight: 387.88. | |
| GPR132 antagonist 1 | GPR132 antagonist 1 is a GPR132 antagonist with EC50 value of 0.075 μM. Synonyms: NOX-6-18. CAS No. 898211-21-7. Molecular formula: C18H17NO5S. Mole weight: 359.40. | |
| GPR132 antagonist 1 | GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 ?M. GPR132 antagonist 1 has promote insulin secretion activity with an EC50 value of 0.7 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 898211-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157189. |  |
| GPR139 agonist-2 | GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC 50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2983118-29-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149651. | |
| GPR139 agonist-2 | GPR139 agonist-2 is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 has the potential for antischizophrenia drug research. Synonyms: (S)-2-(4-Oxopyrrolo[1,2-d][1,2,4]triazin-3(4H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide. CAS No. 2983118-29-0. Molecular formula: C17H15F3N4O3. Mole weight: 380.32. | |
| GPR183 antagonist-2 | GPR183 antagonist-2 (compound 32) is a selective GPR183 antagonist with good water solubility and excellent pharmacokinetic properties. GPR183 antagonist-2 significantly reduces paw and joint swelling and gene expression of pro-inflammatory cytokines (MCP-1, MMPs, and VEGF) in a collagen-induced arthritis (CIA) mouse model in a dose-dependent manner. GPR183 antagonist-2 can be used in the study of autoimmune diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924063-98-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162011. | |
| GPR183-IN-2 | GPR183-IN-2 (compound 23) is a potent GPR183 inhibitor. GPR183-IN-2 inhibits Ca 2+ mobilization with an IC 50 value of 39.45 nM. GPR183-IN-2 has the potential for the research of cancer, autoimmune diseases, pain, and osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924064-10-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163796. | |
| GPR30 agonist-1 | GPR30 agonist-1 is an agonist of G protein-coupled receptor 30 (GPR30) with vasorelaxant effects. Synonyms: 3H-Cyclopenta[c]quinoline, 4-(5-bromo-2-methoxyphenyl)-8-fluoro-3a,4,5,9b-tetrahydro-, (3aS,4R,9bR)-. Grade: ≥98%. CAS No. 415919-74-3. Molecular formula: C19H17BrFNO. Mole weight: 374.25. | |
| GPR34 receptor antagonist | GPR34 receptor antagonist Inhibitor. Uses: Scientific use. Product Category: T8848. CAS No. 907952-06-1. |  |
| GPR34 receptor antagonist 2 | GPR34 receptor antagonist 2 (Compound D2) is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 907952-06-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138501. | |
| GPR34 receptor antagonist 2 | GPR34 receptor antagonist 2 is a GPR34 receptor antagonist. Grade: 97%. CAS No. 907952-06-1. Molecular formula: C31H26ClNO4. Mole weight: 512.0. | |
| GPR34 receptor antagonist 3 | GPR34 receptor antagonist 3 (Compound 5e) is a class of GRP34 antagonists, IC50 is 0.680??M. GPR34 receptor antagonist 3 inhibited ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent way without obvious cytotoxicity. GPR34 receptor antagonist 3 shows antisensory activity in mouse neuropathic pain model [1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155417. | |
| GPR35 activator-1 | GPR35 activator-1 is a potent GPR35 activator with a Ki of 0.08 nM for human GPR35. CAS No. 2855918-34-0. Molecular formula: C25H18N6O4. Mole weight: 466.45. | |
| GPR35 agonist 1 | GPR35 agonist 1 is a potent and specific GPR35/CXCR8 agonist with an EC50 of 5.8 nM. Synonyms: 6-Bromo-7-hydroxy-8-nitro-3-(1H-tetrazol-5-yl)-2H-chromen-2-one. CAS No. 2079880-92-3. Molecular formula: C10H4BrN5O5. Mole weight: 354.07. | |
| GPR35 agonist 5 | GPR35 agonist 5 is a weak GPR35 agonist. Synonyms: 3,5-dinitro-bisphenol A. CAS No. 2226201-24-5. Molecular formula: C15H14N2O6. Mole weight: 318.28. | |
| GPR35 agonist 5 | GPR35 agonist 5 (3,5-dinitro-bisphenol A; compound 6) is a weak GPR35 agonist. GPR35 agonist 5 arrests CHO-S cells at the G1/Gophase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226201-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149190. | |
| GPR35 Agonist, Compound 10 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Gpr35 modulator 1 | Gpr35 modulator 1 is a potent modulator of Gpr35. CAS No. 2994189-01-2. Molecular formula: C23H14ClF2N5O3. Mole weight: 481.84. | |
| Gpr35 modulator 2 | Gpr35 modulator 2 is a potent modulator of Gpr35. CAS No. 3049339-96-7. Molecular formula: C28H23FN2O4. Mole weight: 470.49. | |
| Gpr35 modulator 3 | Gpr35 modulator 3 is a potent modulator of Gpr35. CAS No. 3055887-18-5. Molecular formula: C25H19FN6O2. Mole weight: 454.46. | |
| GPR39-C3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GPR3 agonist-2 | GPR3 agonist-2(compound 32) is a potent full agonist of G protein-coupled receptor 3, with the IC50of 260 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1983120-51-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155318A. | |
| GPR40 Activator 1 | GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. Synonyms: GPR40 Activator 1. Grade: >98%. CAS No. 1309435-60-6. Molecular formula: C31H31NO3S. Mole weight: 497.65. | |
| GPR40 Activator 2 | GPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. Synonyms: GPR40 Activator 2. Grade: >98%. CAS No. 1312787-30-6. Molecular formula: C28H29NO6S2. Mole weight: 539.66. | |
| GPR40 agonist 1 | GPR40 agonist 1 is a potent full agonist of GPR40 with EC50s of 2 and 17 nM for hGPR40 and rGPR40, respectively. Synonyms: Benzenepropanoic acid, β-cyclopropyl-3-[[5-(5-fluoro-2-methoxy-4-pyridinyl)-6-(2-methylpropyl)-2-pyrazinyl]methoxy]-, (βS)-; (3S)-3-Cyclopropyl-3-(3-((5-(5-fluoro-2-methoxypyridin-4-yl)-6-isobutylpyrazin-2-yl)methoxy)phenyl)propanoic acid. Grade: ≥95%. CAS No. 1853982-41-8. Molecular formula: C27H30FN3O4. Mole weight: 479.54. | |
| GPR40 Agonist 2 | GPR40 Agonist 2, an agonist of G-protein coupled receptor 40 (GPR40), can be used in diabetes research. (Extracted from patent WO2009054479A1). Synonyms: Benzenepropanoic acid, β-1-propyn-1-yl-4-(spiro[5.5]undec-2-en-2-ylmethoxy)-, (βS)-; (S)-3-[4-(spiro[5.5]undec-2-en-2-ylmethoxy)-phenyl]-hex-4-ynoic acid; (3S)-3-[4-(Spiro[5.5]undec-2-en-2-ylmethoxy)phenyl]-4-hexynoic acid. CAS No. 1147729-48-3. Molecular formula: C24H30O3. Mole weight: 366.49. | |
| GPR40 Agonist - CAS 885101-89-3 | The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. | |
| GPR40 Agonist II (FFA1 Agonist II, Free Fatty Acid Receptor 1 Agonist II, 3- (4- ( (2, 6-Dichloropyridin-4-yl) ethynyl) phenyl) propanoic Acid) | A cell-permeable alkynedihydrocinnamic acid that acts as a potent GPR40/FFA1 agonist (EC50=40.7nM in inducing Ca2+ mobilization in hFFA1-expressing 1321N1 cells) with >100-fold selectivity over GPR43/FFA2, GPR41/FFA3, and a panel of 56 other receptors, ion channels, and transporters. Reported to enhance 12mM glucose-induced insulin secretion from rat INS-1E B-cells (by 34% at 10uM) and exhibit good aqueous solubility (199uM in PBS at pH 7.4), as well as chemical and metabolic stability. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR40 Antagonist, GW1100 - CAS 306974-70-9 | The GPR40 Antagonist, GW1100, also referenced under CAS 306974-70-9, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy. | |
| GPR40/FFAR1 modulator 1 | GPR40/FFAR1 modulator 1 is an agonist and allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1). Synonyms: 7-({4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl}methoxy)-4-methyl-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl-. Grade: ≥95%. CAS No. 874755-26-7. Molecular formula: C21H19N5O3. Mole weight: 389.41. | |
| GPR43 (FFA2) Agonist ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide) | A phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50=0.7uM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR4 antagonist 1 | A GPR4 antagonist, with an IC50 of 189 nM. Synonyms: GPR4 receptor modulator 46. CAS No. 1197879-16-5. Molecular formula: C27H37N5. Mole weight: 431.62. | |
| GPR52 antagonist-1 | GPR52 antagonist-1 (Compound 43) is a GPR52 antagonist with an IC50 of 0.63 ?M. GPR52 antagonist-1 reduces mHTT (mutant huntingtin protein) levels by targeting GPR52 and promotes survival of mouse primary striatal neurons[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239987-91-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145468. | |
| GPR55 agonist 3 | GPR55 agonist 3 (Compound 26) is a GPR55 agonist ( EC 50 : 0.239 nM, and 1.76 nM for hGPR55 and rGPR55). GPR55 agonist 3 induces β-arrestin recruitment to human GPR55 ( EC 50 : 6.2 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3006105-44-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156107. | |
| GPR55 agonist 3 | GPR55 agonist 3 is a GPR55 agonist and it induces β-arrestin recruitment to human GPR55. CAS No. 3006105-44-5. Molecular formula: C19H16F4N4. Mole weight: 376.35. | |
| GPR55 agonist 4 | GPR55 agonist 4 is a GPR55 agonist and it induces β-arrestin recruitment to human GPR55. CAS No. 3006105-55-8. Molecular formula: C19H16FN5O2. Mole weight: 365.36. | |
| GPR55 Receptor Antagonist, CID16020046 (4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H-pyrrolo[3,4-c]pyrazol-5-yl]benzoic Acid) | A selective antagonist of G protein-coupled receptor 55 (GPR55) that blocks lipid L-a-lysophosphatidyl inositol (LPI)-induced GPR55 activation (IC50 = 1uM) and downstream effects in HEK293 cells. Also shown to block the agonistic effect of LPI on GPR55- expressing yeast cells (~10uM). Inhibits LPI-induced Ca2+ mobilization and ERK1/2 phosphorylation in HEK-GPR55 and HEK-CB1 cells. However, it does not affect basal Ca2+ mobilization and ERK1/2 activity. Blocks the GPR55-mediated NFAT and NF-kB activation and their nuclear translocation in HEK-GPR55 cells. Diminishes LPI-induced wound healing in GPR55-expressing primary human lung microvascular endothelial cells and reverses LPI-inhibited platelet aggregation (~10uM). Also reported to inhibit the activity of phosphodiesterases PDE3A and PDE4B (pIC50 = 5 and 4.8, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| GPR81 agonist 1 | GPR81 agonist 1 is a potent and highly selective GPR81 agonist, with EC50s of 58 nM and 50 nM for human and mouse GPR81, respectively. GPR81 agonist 1 inhibits lipolysis in differentiated 3T3-L1 adipocytes. GPR81 agonist 1 suppresses lipolysis in mice without cutaneous flushing. GPR81 agonist 1 displays remarkable selectivity for GPR81 over GPR109a[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1620992-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135982. | |
| GPR81 Agonist, 3Cl-5OH-BA (3-Chloro-5-hydroxybenzoic Acid, Hydroxycarboxylic Acid Receptor 1 Agonist) | A hydroxybenzoic acid compound that acts as a GPR81/HCA1-selective agonist (EC50 ~7, 16, 17, 22, and 67uM toward rat, human, monkey, mouse, and dog species, respectively) with little activity towards the homologous GPR109A/HCA2/HM74A GPCR. Orally active in mice and exhibits NEFAc cholesterol-lowering efficacy in overnight fasted C57B16/J mice (ED50 ~100mg/kg, p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 53984-36-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| GPR84 antagonist 1 | GPR84 antagonist 1 is a high affinity and highly selective human GPR84 competitive antagonist. Molecular formula: C26H22N4O2. Mole weight: 422.48. | |
| GPR84 antagonist 2 | GPR84 antagonist 2 is a potent, selective and orally active GPR84 antagonist (IC50 = 8.95 nM), which has the potential for the study of ulcerative colitis. It shows improved potency in the calcium mobilization assay and inhibits the chemotaxis of neutrophils and macrophages upon GPR84 activation. Synonyms: Dibenzo[b,f]thiepin-10-ol, 1-chloro-, 10,10'-(hydrogen phosphate), sodium salt (1:1). CAS No. 2244269-74-5. Molecular formula: C28H16Cl2NaO4PS2. Mole weight: 605.42. | |
| GPR84 antagonist 8 | GPR84 antagonist 8 is a selective antagonist of GPR84. Synonyms: 4H-Pyrimido[6,1-a]isoquinolin-4-one, 2-(1,4-dioxan-2-ylmethoxy)-6,7-dihydro-9-(2-pyridinylmethoxy)-; 2-(1,4-Dioxan-2-ylmethoxy)-9-(2-pyridinylmethoxy)-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one. Grade: ≥95%. CAS No. 1445846-30-9. Molecular formula: C23H23N3O5. Mole weight: 421.45. | |
| gpr endopeptidase | Initiates the degradation of small, acid-soluble proteins during spore germination in Bacillus megaterium. Type example of peptidase family M63. Group: Enzymes. Synonyms: germination proteinase. Enzyme Commission Number: EC 3.4.24.78. CAS No. 75718-32-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4362; gpr endopeptidase; EC 3.4.24.78; 75718-32-0; germination proteinase. Cat No: EXWM-4362. |  |
| G Protein Antagonist | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| G-Protein antagonist peptide | G-Protein antagonist peptide is a competitive and reversible inhibitor of M2 muscarinic cholinergic receptors. G-Protein antagonist peptide inhibits M2 muscarinic receptor activation of Gi or Go and suppresses Gs activation by β-adrenoceptors. Synonyms: GPAnt-2; G Protein Antagonist. Grade: >98%. CAS No. 143675-79-0. Molecular formula: C57H64N12O9S. Mole weight: 1093.27. | |
| G-Protein antagonist peptide acetate | G-Protein antagonist peptide is a competitive and reversible inhibitor of M2 muscarinic cholinergic receptors. G-Protein antagonist peptide inhibits M2 muscarinic receptor activation of Gi or Go and suppresses Gs activation by β-adrenoceptors. Synonyms: GPAnt-2 acetate; G Protein Antagonist acetate. Molecular formula: C59H68N12O11S. Mole weight: 1153.33. | |
| G-protein coupled receptor 143 (126-134) | G-protein coupled receptor 143 (126-134) is a 9-aa peptide. G-protein coupled receptor 143 is a receptor for tyrosine, L-DOPA and dopamine. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Synonyms: Ocular albinism type 1 protein (126-134). | |
| G-protein-coupled receptor kinase | Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate. (cf. EC 2.7.11.14, rhodopsin kinase and EC 2.7.11.15, β-adrenergic-receptor kinase). Group: Enzymes. Synonyms: G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Enzyme Commission Number: EC 2.7.11.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3135; G-protein-coupled receptor kinase; EC 2.7.11.16; G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Cat No: EXWM-3135. | |
| GPRP | GPRP is an inhibitor of fibrin polymerization. It binds to fibrinogen (Ki = 400 mM). Synonyms: Gly-pro-arg-pro; L-Proline,glycyl-L-prolyl-L-arginyl-; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid. CAS No. 67869-62-9. Molecular formula: C18H31N7O5. Mole weight: 425.48. | |
| GPRP | GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: Gly-Pro-Arg-Pro; Pefa 6003. CAS No. 67869-62-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0074. | |
| GPRP acetate | GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2][3]. Uses: Scientific research. Group: Peptides. Alternative Names: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate. CAS No. 157009-81-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0074A. | |
| GPRP acetate | GPRP acetate, a fibrinogen-related peptide, inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). Synonyms: Pefa 6003; Pefabloc FG; GPRP.CH3CO2H; glycyl-L-prolyl-L-arginyl-L-proline acetic acid; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid acetate; H-Gly-Pro-Arg-Pro-OH acetate. Grade: ≥95%. CAS No. 157009-81-9. Molecular formula: C18H31N7O5.C2H4O2. Mole weight: 485.53. | |
| GPS491 | GPS491 (EC50 = 0.47 μM) inhibits the expression of HIV-1 structural protein Gag, changes the accumulation of HIV-1 RNA, reduces the abundance of RNAs encoding the structural proteins, and increases the level of viral RNAs encoding the regulatory proteins. Synonyms: 2-(trifluoromethyl)-N-(6-(trifluoromethyl)benzo[d]thiazol-2-yl)thiazole-5-carboxamide. Grade: ≥98%. CAS No. 2655502-29-5. Molecular formula: C13H5F6N3OS2. Mole weight: 397.32. | |
| GPV574 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GPX100 | GPX-100 is an analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. GPX-100 was designed to be a non-cardiotoxic anthracycline antibiotic. Synonyms: Epirubicin Impurity 1; 13-Deoxyepirubicin; GPX 100; GPX-100; 13-deoxy-doxorubicin; (1S,3R)-3,5,12-Trihydroxy-3-(2-hydroxyethyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-1-methoxy-, (8R,10S)-. Grade: ≥95%. CAS No. 952648-77-0. Molecular formula: C27H31NO10. Mole weight: 529.54. | |
| GPX150 | GPX-150 is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis. Synonyms: GPX 150; GPX-150; 5(8H)-Naphthacenone, 10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-, (8R,10S)-. CAS No. 236095-29-7. Molecular formula: C27H32N2O9. Mole weight: 528.56. | |
| GPX1 human | recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| GPX4-IN-3 | GPX4-IN-3 is an effective inhibitor of glutathione peroxidase 4 (GPX4) and can be used as a selective ferroptosis inducer. It shows 71.7% inhibition for GPX4 with 1 μM. Synonyms: NSC-835419; 2-(benzo[b]thiophen-3-yl)-2-(2-chloro-N-(4-(oxazol-5-yl)phenyl)acetamido)-N-phenethylacetamide. Grade: ≥95%. Molecular formula: C29H24ClN3O3S. Mole weight: 530.04. | |
| GPX4-IN-3 | GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2761004-85-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141809. | |
| GPX4-IN-4 | GPX4-IN-4 (Compound 24) is a potent GPX4 inhibitor. GPX4-IN-4 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2920221-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149923. | |
| GPX4-IN-5 | GPX4-IN-5 is a covalent inhibitor of GPX4 (IC50: 0.12 ?M). GPX4-IN-5 can induce ferroptosis and has anti-tumor effects. GPX4-IN-5 can be used in the study of triple-negative breast cancer (TNBC)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922824-09-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-155663. | |
| GQ-16 | GQ-16 is an effective and partial agonist for peroxisome proliferator-activated receptor γ (PPARγ) (Ki = 160 nM). It does not activate PPARα, PPARβ/δ, or RXRα. Synonyms: 5Z-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione. Grade: ≥98%. CAS No. 870554-67-9. Molecular formula: C19H16BrNO3S. Mole weight: 418.3. | |
| GQ-16 | GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARγ , exhibiting a K i of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPAR&gamma. GQ-16 is a partial agonist of PPARγ with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 870554-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111254. | |
| GQ1b-Ganglioside | GQ1b-Ganglioside is a vital biomedical product utilized for its neuroprotective properties. This compound acts as a crucial element in the treatment of various neurological disorders, including Guillain-Barré syndrome and Miller Fisher syndrome. Synonyms: Tetrasialoganglioside 1b; Ganglioside GQ1b; GQ1b. CAS No. 68652-37-9. | |
| GQ3-Oligosaccharide | GQ3-Oligosaccharide is an extraordinary bioactive compound employed in the research of neurodegenerative ailments, showcasing remarkable neuroprotective attributes. GQ3-Oligosaccharide actively contributes to the diminution of oxidative stress and inflammation, thereby facilitating the augmentation of neuronal viability and efficacious functioning. Synonyms: Neu5Aca2-8Neu5Aca2-8Neu5Acb2-8Neu5Aca2-3Galb1-4Glc. Molecular formula: C56H86N4O43Na4. Mole weight: 1595.24. | |
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