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| Product | Description | |
|---|---|---|
| GP3G (Unmethylated Cap Analog) | GP3G is a kind of diguanosine polyphosphate, could be found in human plasma. Synonyms: GpppG; G(5')ppp(5')G Cap Analog; Diguanosine triphosphate; Diguanosine-5'-triphosphate; P1-(Guanosyl) P3-(5'-(guanosyl))triphosphate; CAP; Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with guanosine; Guanosine 5'-(tetrahydrogen triphosphate), 5'→5'-ester with guanosine; Guanosine triphosphate, 5'→5'-ester with guanosine; Guanosine, 5'-ester with guanosine 5'-(tetrahydrogen triphosphate); Diguanosine 5',5'''-triphosphate; Gp3G; P1,P3-Diguanosine 5'-triphosphate; Guanosine-5'-triphosphate-5'-Guanosine. Grade: ≥95% by HPLC. CAS No. 6674-45-9. Molecular formula: C20H27N10O18P3. Mole weight: 788.41. |  |
| GP4G | GP4G, a naturally occurring compound found in green tea and seaweed, is a multifunctional ingredient commonly employed as a dietary supplement and cosmetic product ingredient. Various investigations indicate its significant role in augmenting skin cell metabolism and safeguarding against ultraviolet radiation-induced harm. Moreover, studies exhibit the potential of GP4G in bolstering brain function and exercise performance. The compound is also a promising candidate in treating afflictions such as Alzheimer's disease and stroke. Synonyms: P1-(5'-Guanosyl)-P4-(5'-guanosyl)-tetraphosphate. Grade: ≥ 95 % by HPLC. Molecular formula: C20H28N10O21P4. Mole weight: 868.39. | |
| Gp4U | Gp4U is an innovative and groundbreaking biomedical compound, used for studying diverse malignancies such as breast, lung and colon cancer. Synonyms: P1- (5'- Guanosyl)- P4- (5'- uridyl)- tetraphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 79695-25-3. Molecular formula: C19H27N7O22P4 (free acid). Mole weight: 829.4 (free acid). | |
| GP531 | GP531 is a novel riboside with similar structural and anti-ischemic properties to the adenosine-regulating agent (ARA) acadesine. Synonyms: 5-amino-1-[(2R,3R,4S,5R)-5-[(benzylamino)methyl]-3,4-dihydroxyoxolan-2-yl]imidazole-4-carboxamide; 5-amino-1-beta-D-(5'-benzylamino-5'-deoxyribofuranosyl)imidazole-4-carboxamide; GP 531; GP-531; GP531. CAS No. 142344-87-4. Molecular formula: C16H21N5O4. Mole weight: 347.37. | |
| gp91 ds-tat | gp91 ds-tat is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. It acts as a NADPH oxidase inhibitor. Synonyms: H-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln-Leu-NH2. CAS No. 329902-61-6. Molecular formula: C98H190N50O22S. Mole weight: 2452.94. | |
| gp91 ds-tat | gp91 ds-tat, a biological active peptide, is a NADPH oxidase 2 (Nox2) inhibitor. gp91 ds-tat blocks NADPH oxidase-dependent superoxide production. gp91 ds-tat ameliorates high glucose-induced increase in total ROS, LPOs and iron levels. gp91 ds-tat inhibits homocysteine (Hcy)-induced activation of NLRP3 inflammasomes and restores Hcy-inhibited lysosomal TRPML1 channel activity. gp91 ds-tat improves cerebrovascular and cognitive function in APP/PS1 mice. gp91 ds-tat can be used for the study of Alzheimers disease (AD), glomerular inflammation and cardiovascular disease[1][2][3][4]. Uses: Scientific research. Group: Peptides. CAS No. 329902-61-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5381. |  |
| GP-AMC, Fluorogenic Substrate | GP-AMC, Fluorogenic Substrate. Synonyms: Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide; Gly-Pro-7-amido-4-methylcoumarin hydrobromide; L-Prolinamide, glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, monohydrobromide (9CI). Grade: >97%. CAS No. 115035-46-6. Molecular formula: C17H20BrN3O4. Mole weight: 410.26. | |
| GP Antagonist-2A | The GP Antagonist-2A controls the biological activity of GP. This small molecule/inhibitor is primarily used for Neuroscience applications. Group: Fluorescence/luminescence spectroscopy. |  |
| GpAp | GpAp is a synthetic linear dinucleotide not binding to the c-diGMP-I riboswitch. Synonyms: Guanylyl- (3' -≥ 5')- adenosine- 3'- O- phosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 17332-08-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4. | |
| GPBAR1-IN-3 | GPBAR1-IN-3, a CysLT1R antagonist, is a selective GPBAR1 agonist with an EC50 of 0.17 μM. Synonyms: (S)-2-((3-(2-methylbutoxy)phenoxy)methyl)quinoline. Molecular formula: C21H23NO2. Mole weight: 321.41. | |
| GPBAR-A | GPBAR-A is a GPBA receptor agonist. GPBAR-A increases GLP-1 secretion from intestinal cultures. Synonyms: GPBAR-A; GPBAR A; GPBARA; 4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one. Grade: ≥98% by HPLC. CAS No. 877052-79-4. Molecular formula: C23H15F7N2O2. Mole weight: 484.37. | |
| GPBAR-A | GPBAR-A. Group: Biochemicals. Grades: Purified. CAS No. 877052-79-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GpCp | GpCp is an analogue of GDP and has been found to be hydrolytically stable. Synonyms: GMPCP; Guanosine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 32381-15-0. Molecular formula: C11H14N5Na3O10P2. Mole weight: 507.20. | |
| GpCpp | GpCpp is an analogue of GTP and could be used as a stabilizer in some microtubule cryoelectron microscopy studies. Uses: Antiviral agents. Synonyms: GMPCPP; Guanosine-5'-[(α,β)-methyleno]triphosphate. Grade: ≥ 95 % by HPLC. CAS No. 14997-54-7. Molecular formula: C11H18N5O13P3. Mole weight: 521.21. | |
| GPCR agonist-2 | GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC 50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 291528-35-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-47823. | |
| GPCR Compound Library | A unique collection of 1633 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; - Potential to find new GPCR drug candidates by screening against orphan GPCRs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include 5-HT receptor, dopamine receptor, opioid receptor, adrenergic receptor, mGluR, Cannabinoid receptor, ETA-receptor, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1500. Categories: GPCR Compounds Libraries. |  |
| GPCR Compound Library Plus | Quantity: well-chosen 338 GPCR targeting compounds with unique structures; - High bioactivity: All compounds with IC50 below 3. 5 μM; - Targets include 21 various GPCR subtypes; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - HNMR/LCMS validated to ensure high purity and quality; - A powerful tool for GPCR drug development and target identification. Uses: Scientific use. Product Category: L1580. Categories: GPCR Compounds Libraries Plus. | |
| GPCR-Helix 8 Signaling Inhibitor, JF5 (GPCR-H8 Signaling Inhibitor, JF5, 4-Pentyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-imine, HI, 4-Pentyl-1,2,3,4-tetrahydro-9H-cyclopenta[b]quinolin-9-imine, HI) | A cell-permeable quinolinimine compound that acts as a selective, potent blocker of G-protein coupled receptors (GPCR) that contain a constrained eighth helix (H8). The inhibition is selective and blocks G-protein signaling mediated via Gaq, but not Ga12. A non-orthosteric antagonist of PAR1 (IC50=4uM) that is shown to inhibit PAR1 and CCR-4 induced platelet aggregation without affecting PAR4 mediated aggregation. Shown to inhibit thrombus formation following vascular injury (IC50 ~1mg/kg). Also acts as a potent, non-competitive blocker of a2A-adrenergic receptors (IC50=2.5uM as shown by a decrease in 3H-yohimbine binding). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPCR modulator-1 | GPCR modulator-1 is a negative allosteric modulator of GLP receptor. GPCR modulator-1 has the potential for type 2 diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1407592-99-7. Pack Sizes: 1 mg. Product ID: HY-124803. | |
| GPDA | GPDA(Glycylproline p-nitroanilide tosylate) is the substarate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: GPN; Glycylproline p-nitroanilide tosylate. CAS No. 65096-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16710. | |
| G-PET PETG 3D Printing Filament | G-PET PETG 3D Printing Filament. Group: 3d printing materials. |  |
| GPI-15427 | GPI-15427 is a potent PARP-1 inhibitor capable of crossing the blood-brain barrier, which can significantly increased the antitumor activity of the methylating agent TMZ against malignant melanoma, glioblastoma multiforme, or lymphoma growing at the CNS site. GPI-15427 acts as a potent inhibitor of the enzyme, being capable of inhibiting the activity of purified PARP-1 at nanomolar concentrations. GPI-15427 induced significant sensitization to radiotherapy, representing a promising new treatment in the management of HNSCC. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: GPI 15427; GPI15427; 10-((4-Methylpiperazin-1-yl)methyl)chromeno(4,3,2-de)phthalazin-3(2H)-one. CAS No. 805242-85-7. Molecular formula: C20H20N4O2. Mole weight: 348.41. | |
| GPi 688 | GPi 688 is an allosteric glycogen phosphorylase inhibitor that inhibits glucagon-mediated hyperglycemia in the rat. Synonyms: GPi 688; GPi688; GPi-688; 2-Chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl]-6H-thieno[2,3-b]pyrrole-5-carboxamide. Grade: ≥99% by HPLC. CAS No. 918902-32-6. Molecular formula: C19H18ClN3O4S. Mole weight: 419.88. | |
| GPLGIAGQ | GPLGIAGQ, is an MMP2-cleaved polypeptide that is used as a stimulus-sensitive connector in both liposomes and micelle nanoceroses for targeted therapy of tumors triggered by MMP2. Synonyms: L-Glutamine, glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-; Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln. Grade: ≥97% by HPLC. CAS No. 109053-09-0. Molecular formula: C31H53N9O10. Mole weight: 711.81. | |
| GPNA hydrochloride | GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase ( GGT ). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na + -dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na + -independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67953-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W011391. | |
| GPP 78 | GPP 78 is a potent inhibitor of Nicotinamide phosphoribosyltransferase (Nampt) with an IC50 value of 3 nM. Synonyms: CAY10618; NMPRTase Inhibitor; N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-1H-1,2,3-triazole-1-octanamide. Grade: ≥95%. CAS No. 1202580-59-3. Molecular formula: C27H29N5O. Mole weight: 439.6. | |
| GPP 78 hydrochloride | GPP 78 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GPP 78 hydrochloride | GPP 78 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), which is subsequently converted to NAD+. It was shown to induce autophagy in neuroblastoma cells. Synonyms: GPP 78 hydrochloride; GPP78 hydrochloride; GPP-78 hydrochloride; N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride. Grade: ≥98% by HPLC. Molecular formula: C27H29N5O.HCl. Mole weight: 476.01. | |
| GppNH2 | GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPN; Guanosine-5'-(β-amino)-diphosphate. Grade: ≥ 95 % by HPLC. Molecular formula: C10H16N6O10P2. Mole weight: 442.21. | |
| GppNHp - Tetralithium salt | The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Tetralithium salt; GMPPNHP. Grade: ≥ 95 % by HPLC. CAS No. 64564-03-0. Molecular formula: C10H13N6ONa413P3. Mole weight: 611.13. | |
| GppNHp - Trisodium salt | The trisodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Trisodium salt; GMPPNHP. Grade: ≥ 90 % by HPLC. CAS No. 148892-91-5. Molecular formula: C10H14N6Na3O13P3. Mole weight: 588.14. | |
| GPR109b Agonist (1-(iso-Propyl)-1H-benzotriazole-5-carboxylic Acid) | A cell-permeable Niacin triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or b-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5uM) and isoproterenol (1uM), respectively, in GPR109b-expressing CHO cells (EC50=400nM) and freshly isolated human adipocytes (EC50 about 1uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 306935-41-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| GPR109b Agonist - CAS 306935-41-1 | The GPR109b Agonist, also referenced under CAS 306935-41-1, controls the biological activity of GPR109b. This small molecule/inhibitor is primarily used for Activators/Inducers applications. Group: Fluorescence/luminescence spectroscopy. | |
| GPR119 Agonist, AS1269574 (G-Protein Coupled Receptor 119 Agonist, 2-((2-(4-Bromophenyl)-6-methylpyrimidin-4-yl)amino)ethanol, GPCR2 Agonist, MGC119957 Agonist, SNORF25 Agonist) | A pyrimidine compound that acts as an effective GPR119 agonist (EC50=2.5uM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward B-adrenergic or GLP-1 receptors. Shown to enhance 16.8mM glucose-induced insulin secretion from murine MIN-6 B-cells (mU/20 min=0.44 and 0.22, respectively, with or without 10uM AS1269574) in vitro and improve glucose tolerance in normal mice (100mg/kg; p.o.) without any significant hypoglycemic effect in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 330981-72-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR120 Agonist 1 | GPR120 Agonist 1 is a potent and selective GPR120 agonist with promising antidiabetic effects and good safety. Synonyms: GPR120 agonist 4x; 3-(4-((3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl)methoxy)-3,5-difluorophenyl)propanoic acid; Benzenepropanoic acid, 4-[[3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)-4-isothiazolyl]methoxy]-3,5-difluoro-. Grade: ≥95%. CAS No. 1628448-77-0. Molecular formula: C20H12ClF6NO3S. Mole weight: 495.82. | |
| GPR120-IN-1 | GPR120-IN-1, a cell-permeable azaspiroundecanyl acetic acid compound, is an orally available, selective agonist of GPR120 (EC50 = ~0.35 μM) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1). Synonyms: 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid; GPR120 Compound A; MDK77754; MDK-77754; MDK 77754; GPR120 cpdA. CAS No. 1599477-75-4. Molecular formula: C19H23ClF3NO3. Mole weight: 405.84. | |
| GPR120 modulator 1 | GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 1; 1050506-75-6; 2-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenoxy]acetic acidAcetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]-GPR120-modulator-1. Grade: >98%. CAS No. 1050506-75-6. Molecular formula: C19H16ClNO4S. Mole weight: 389.85. | |
| GPR120 modulator 2 | GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 2; 1050506-87-0; 3-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenyl]propanoic acidBenzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl-3-(4-{[4-(2-CHLOROPHENYL)-1,3-THIAZOL-2-YL]METHOXY}-2-METHYLPHENYL)PROPANOIC ACID. Grade: >98%. CAS No. 1050506-87-0. Molecular formula: C20H18ClNO3S. Mole weight: 387.88. | |
| GPR132 antagonist 1 | GPR132 antagonist 1 is a GPR132 antagonist with EC50 value of 0.075 μM. Synonyms: NOX-6-18. CAS No. 898211-21-7. Molecular formula: C18H17NO5S. Mole weight: 359.40. | |
| GPR132 antagonist 1 | GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 ?M. GPR132 antagonist 1 has promote insulin secretion activity with an EC50 value of 0.7 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 898211-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157189. | |
| GPR139 agonist-2 | GPR139 agonist-2 is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 has the potential for antischizophrenia drug research. Synonyms: (S)-2-(4-Oxopyrrolo[1,2-d][1,2,4]triazin-3(4H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide. CAS No. 2983118-29-0. Molecular formula: C17H15F3N4O3. Mole weight: 380.32. | |
| GPR139 agonist-2 | GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC 50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2983118-29-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149651. | |
| GPR183 antagonist-2 | GPR183 antagonist-2 (compound 32) is a selective GPR183 antagonist with good water solubility and excellent pharmacokinetic properties. GPR183 antagonist-2 significantly reduces paw and joint swelling and gene expression of pro-inflammatory cytokines (MCP-1, MMPs, and VEGF) in a collagen-induced arthritis (CIA) mouse model in a dose-dependent manner. GPR183 antagonist-2 can be used in the study of autoimmune diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924063-98-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162011. | |
| GPR183-IN-2 | GPR183-IN-2 (compound 23) is a potent GPR183 inhibitor. GPR183-IN-2 inhibits Ca 2+ mobilization with an IC 50 value of 39.45 nM. GPR183-IN-2 has the potential for the research of cancer, autoimmune diseases, pain, and osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924064-10-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163796. | |
| GPR30 agonist-1 | GPR30 agonist-1 is an agonist of G protein-coupled receptor 30 (GPR30) with vasorelaxant effects. Synonyms: 3H-Cyclopenta[c]quinoline, 4-(5-bromo-2-methoxyphenyl)-8-fluoro-3a,4,5,9b-tetrahydro-, (3aS,4R,9bR)-. Grade: ≥98%. CAS No. 415919-74-3. Molecular formula: C19H17BrFNO. Mole weight: 374.25. | |
| GPR34 receptor antagonist | GPR34 receptor antagonist Inhibitor. Uses: Scientific use. Product Category: T8848. CAS No. 907952-06-1. | |
| GPR34 receptor antagonist 2 | GPR34 receptor antagonist 2 (Compound D2) is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 907952-06-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138501. | |
| GPR34 receptor antagonist 2 | GPR34 receptor antagonist 2 is a GPR34 receptor antagonist. Grade: 97%. CAS No. 907952-06-1. Molecular formula: C31H26ClNO4. Mole weight: 512.0. | |
| GPR34 receptor antagonist 3 | GPR34 receptor antagonist 3 (Compound 5e) is a class of GRP34 antagonists, IC50 is 0.680??M. GPR34 receptor antagonist 3 inhibited ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent way without obvious cytotoxicity. GPR34 receptor antagonist 3 shows antisensory activity in mouse neuropathic pain model [1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155417. | |
| GPR35 activator-1 | GPR35 activator-1 is a potent GPR35 activator with a Ki of 0.08 nM for human GPR35. CAS No. 2855918-34-0. Molecular formula: C25H18N6O4. Mole weight: 466.45. | |
| GPR35 agonist 1 | GPR35 agonist 1 is a potent and specific GPR35/CXCR8 agonist with an EC50 of 5.8 nM. Synonyms: 6-Bromo-7-hydroxy-8-nitro-3-(1H-tetrazol-5-yl)-2H-chromen-2-one. CAS No. 2079880-92-3. Molecular formula: C10H4BrN5O5. Mole weight: 354.07. | |
| GPR35 agonist 5 | GPR35 agonist 5 is a weak GPR35 agonist. Synonyms: 3,5-dinitro-bisphenol A. CAS No. 2226201-24-5. Molecular formula: C15H14N2O6. Mole weight: 318.28. | |
| GPR35 agonist 5 | GPR35 agonist 5 (3,5-dinitro-bisphenol A; compound 6) is a weak GPR35 agonist. GPR35 agonist 5 arrests CHO-S cells at the G1/Gophase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226201-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149190. | |
| GPR35 Agonist, Compound 10 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Gpr35 modulator 1 | Gpr35 modulator 1 is a potent modulator of Gpr35. CAS No. 2994189-01-2. Molecular formula: C23H14ClF2N5O3. Mole weight: 481.84. | |
| Gpr35 modulator 2 | Gpr35 modulator 2 is a potent modulator of Gpr35. CAS No. 3049339-96-7. Molecular formula: C28H23FN2O4. Mole weight: 470.49. | |
| Gpr35 modulator 3 | Gpr35 modulator 3 is a potent modulator of Gpr35. CAS No. 3055887-18-5. Molecular formula: C25H19FN6O2. Mole weight: 454.46. | |
| GPR39-C3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GPR3 agonist-2 | GPR3 agonist-2(compound 32) is a potent full agonist of G protein-coupled receptor 3, with the IC50of 260 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1983120-51-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155318A. | |
| GPR40 Activator 1 | GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. Synonyms: GPR40 Activator 1. Grade: >98%. CAS No. 1309435-60-6. Molecular formula: C31H31NO3S. Mole weight: 497.65. | |
| GPR40 Activator 2 | GPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. Synonyms: GPR40 Activator 2. Grade: >98%. CAS No. 1312787-30-6. Molecular formula: C28H29NO6S2. Mole weight: 539.66. | |
| GPR40 agonist 1 | GPR40 agonist 1 is a potent full agonist of GPR40 with EC50s of 2 and 17 nM for hGPR40 and rGPR40, respectively. Synonyms: Benzenepropanoic acid, β-cyclopropyl-3-[[5-(5-fluoro-2-methoxy-4-pyridinyl)-6-(2-methylpropyl)-2-pyrazinyl]methoxy]-, (βS)-; (3S)-3-Cyclopropyl-3-(3-((5-(5-fluoro-2-methoxypyridin-4-yl)-6-isobutylpyrazin-2-yl)methoxy)phenyl)propanoic acid. Grade: ≥95%. CAS No. 1853982-41-8. Molecular formula: C27H30FN3O4. Mole weight: 479.54. | |
| GPR40 Agonist 2 | GPR40 Agonist 2, an agonist of G-protein coupled receptor 40 (GPR40), can be used in diabetes research. (Extracted from patent WO2009054479A1). Synonyms: Benzenepropanoic acid, β-1-propyn-1-yl-4-(spiro[5.5]undec-2-en-2-ylmethoxy)-, (βS)-; (S)-3-[4-(spiro[5.5]undec-2-en-2-ylmethoxy)-phenyl]-hex-4-ynoic acid; (3S)-3-[4-(Spiro[5.5]undec-2-en-2-ylmethoxy)phenyl]-4-hexynoic acid. CAS No. 1147729-48-3. Molecular formula: C24H30O3. Mole weight: 366.49. | |
| GPR40 Agonist - CAS 885101-89-3 | The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. | |
| GPR40 Agonist II (FFA1 Agonist II, Free Fatty Acid Receptor 1 Agonist II, 3- (4- ( (2, 6-Dichloropyridin-4-yl) ethynyl) phenyl) propanoic Acid) | A cell-permeable alkynedihydrocinnamic acid that acts as a potent GPR40/FFA1 agonist (EC50=40.7nM in inducing Ca2+ mobilization in hFFA1-expressing 1321N1 cells) with >100-fold selectivity over GPR43/FFA2, GPR41/FFA3, and a panel of 56 other receptors, ion channels, and transporters. Reported to enhance 12mM glucose-induced insulin secretion from rat INS-1E B-cells (by 34% at 10uM) and exhibit good aqueous solubility (199uM in PBS at pH 7.4), as well as chemical and metabolic stability. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR40 Antagonist, GW1100 - CAS 306974-70-9 | The GPR40 Antagonist, GW1100, also referenced under CAS 306974-70-9, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy. | |
| GPR40/FFAR1 modulator 1 | GPR40/FFAR1 modulator 1 is an agonist and allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1). Synonyms: 7-({4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl}methoxy)-4-methyl-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 7-[[4-amino-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methoxy]-4-methyl-. Grade: ≥95%. CAS No. 874755-26-7. Molecular formula: C21H19N5O3. Mole weight: 389.41. | |
| GPR43 (FFA2) Agonist ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide) | A phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50=0.7uM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GPR4 antagonist 1 | A GPR4 antagonist, with an IC50 of 189 nM. Synonyms: GPR4 receptor modulator 46. CAS No. 1197879-16-5. Molecular formula: C27H37N5. Mole weight: 431.62. | |
| GPR52 antagonist-1 | GPR52 antagonist-1 (Compound 43) is a GPR52 antagonist with an IC50 of 0.63 ?M. GPR52 antagonist-1 reduces mHTT (mutant huntingtin protein) levels by targeting GPR52 and promotes survival of mouse primary striatal neurons[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239987-91-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145468. | |
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