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| Product | Description | |
|---|---|---|
| GW6471 | GW6471 is a PPARα antagonist (IC50 = 0.24 μM). GW6471 enhances the binding affinity of the PPARα ligand-binding domain to the co-repressor proteins SMRT and NCoR. Synonyms: GW-6471; GW 6471; Propanamide, N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-; N-[ (2S) -2-[[ (1Z) -1-Methyl-3-oxo-3-[4- (trifluoromethyl) phenyl]-1-propen-1-yl]amino]-3-[4-[2- (5-methyl-2-phenyl-4-oxazolyl) ethoxy]phenyl]propyl]propanamide; Propanamide, N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propenyl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-; (S,Z)-N-(3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-((4-oxo-4-(4-(trifluoromethyl)phenyl)but-2-en-2-yl)amino)propyl)propionamide. Grades: ≥95%. CAS No. 880635-03-0. Molecular formula: C35H36F3N3O4. Mole weight: 619.67. |  |
| GW 6471 | GW 6471 is a peroxisome proliferator-activated receptor α (PPARα) antagonist. GW 6471 has been shown to enhance the binding affinity of the PPARα ligand-binding domain to the co-repressor proteins SMRT and NCoR. Group: Biochemicals. Alternative Names: N- [ (2S) -2- [ [ (1Z) -1-Methyl-3-oxo-3- [4- (trifluoromethyl) phenyl] -1-propen-1-yl] amino] -3- [4- [2- (5-methyl-2-phenyl-4-oxazolyl) ethoxy] phenyl] propyl] propanamide; N- [ (2S) -2- [ [ (1Z) -1-Methyl-3-oxo-3- [4- (trifluoromethyl) phenyl] -1-propenyl] amino] -3- [4- [2- (5-methyl-2-phenyl-4-oxazolyl) ethoxy] phenyl] propyl] propanamide. Grades: Highly Purified. CAS No. 880635-03-0. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| GW-6604 | GW6604 is a potent and selective ALK-5 inhibitor with an IC(50) of 140 nM and in a cellular assay inhibited TGF-beta-induced transcription of PAI-1 (IC(50): 500 nM). In vivo, GW6604 (40 mg kg(-1) p.o.) increased liver regeneration in TGF-beta-overexpressing mice, which had undergone partial hepatectomy. Uses: Alk-5 inhibitor. Synonyms: GW6604; GW-6604; GW 6604. 2-phenyl-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine. Grades: ≥98%. CAS No. 452342-37-9. Molecular formula: C19H14N4. Mole weight: 298.34. | |
| GW 7647 | GW 7647 is a potent and highly selective PPARα agonist (EC50 = 6, 1100 and 6200 nM for human PPARα, PPARγ and PPARδ receptors, respectively) with 200-fold selectivity over PPARγ and PPAR&delta. GW 7647 modulates oleate metabolism and mitochondrial enzyme gene expression in mature myotubules in vitro via activating PPAR&alpha. GW 7647 exhibits lipid-lowering and anti-inflammatory effects. Synonyms: GW-7647; GW 7647; GW7647. 2-[[4-[2-[[ (Cyclohexylamino) carbonyl] (4-cyclohexylbutyl) amino]ethyl]phenyl]thio]-2-methylpropanoic acid. Grades: ≥99% by HPLC. CAS No. 265129-71-3. Molecular formula: C29H46N2O3S. Mole weight: 502.75. | |
| GW788388 | GW788388 is a selective inhibitor of TGF-beta type I receptor (TGF-βR1/ALK5; IC50=18 nM) with a much improved pharmacokinetic profile compared with SB431542. It inhibited both the TGF-beta type I and type II receptor kinase activities, but not that of the related bone morphogenic protein type II receptor. Synonyms: GW-788388; N-(oxan-4-yl)-4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]benzamide. Grades: >98%. CAS No. 452342-67-5. Molecular formula: C25H23N5O2. Mole weight: 425.492. | |
| GW 788388 | GW 788388. Group: Biochemicals. Alternative Names: 4-[4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-2-pyridinyl]-N-(tetrahydro-2H-pyran-4-yl)benzamide. Grades: Highly Purified. CAS No. 452342-67-5. Pack Sizes: 10mg. Molecular Formula: C25H23N5O2, Molecular Weight: 425.48. US Biological Life Sciences. | Worldwide |
| GW 788388-d5 | GW 788388-d5. Group: Biochemicals. Alternative Names: 4-[4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-2-pyridinyl]-N-(tetrahydro-2H-pyran-4-yl)benzamide-d5. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H18D5N5O2, Molecular Weight: 430.51. US Biological Life Sciences. | Worldwide |
| GW791343 | GW791343, as a P2X7 receptor antagonist, was a negative allosteric modulator of the human P2X(7) receptor but at the rat P2X(7) receptor its predominant effect was positive allosteric modulation. Uses: P2x7 receptor antagonist. Synonyms: GW-791343; GW791343. Grades: ≥98%. CAS No. 309712-73-0. Molecular formula: C20H24F2N4O. Mole weight: 374.4. | |
| GW 791343 dihydrochloride | The hydrochlorie salt form of GW791343 that is a non-competitive inhibitor of human P2X7 receptors amd it seems to show species-specific activity which is probably negative allosteric modulators of the human P2X7 receptor and the agonist of the same recep. Uses: The hydrochlorie salt form of gw791343 that is a non-competitive inhibitor of human p2x7 receptors. Synonyms: GW791343 (dihydrochloride); 1019779-04-4; 2-((3,4-Difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide dihydrochloride; GW 791343; GW-791343; 3075AH. Grades: >99 %. CAS No. 1019779-04-4. Molecular formula: C20H26Cl2F2N4O. Mole weight: 447.3. | |
| GW791343 dihydrochloride | GW791343 dihydrochloride is a potent human P2X7 receptor negative allosteric modulator (exhibits species-specific activity), produces a non-competitive antagonist effect on human P2X7 receptor, with a pIC 50 of 6.9-7.2. GW791343 dihydrochloride can enhance ATP rhythm. GW791343 dihydrochloride can be used in study of neurological disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1019779-04-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15469. |  |
| GW 791343 hydrochloride | GW 791343 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 309712-55-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GW 791343 trihydrochloride | GW791343 HCl is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7. Synonyms: GW791343; GW 791343; GW-791343; 1019779-04-4. Grades: >98%. CAS No. 309712-55-8. Molecular formula: C20H24F2N4O.3HCl. Mole weight: 483.81. | |
| GW 791343 Trihydrochloride | GW 791343 Trihydrochloride. Group: Biochemicals. Alternative Names: 2-[ (3, 4-Difluorophenyl) amino]-N-[2-methyl-5- (1-piperazinylmethyl) phenyl]acetamide Trihydrochloride. Grades: Highly Purified. CAS No. 1019779-04-4. Pack Sizes: 10mg. Molecular Formula: C20H27Cl3F2N4O, Molecular Weight: 447.35. US Biological Life Sciences. | Worldwide |
| GW 803430 | GW 803430 is a potent and selective melanin-concentrating hormone receptor 1 (MCH1) antagonist (IC50 = 9.3 nM). GW 803430 exhibits antiobesity and antidepressant-like effects in rats and mice. Synonyms: GW-803430; GW 803430; GW803430. 6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one. Grades: ≥99% by HPLC. CAS No. 515141-51-2. Molecular formula: C25H24ClN3O3S. Mole weight: 481.99. | |
| GW841819X | GW841819X, a benzodiazepin derivative, has been found to be a BET bromodomains inhibitor that could be probably significant in the study of myeloma and leukemia at some extent. Synonyms: KB-75882; KB 75882; KB75882; benzyl (1-methyl-6-phenyl-4hbenzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)carbamate. Grades: 98%. CAS No. 146135-18-4. Molecular formula: C25H21N5O2. Mole weight: 423.48. | |
| GW842166X | GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Synonyms: GW-842166X; 842166X; 842166; GW-842166; GW842166X; GW842166; GW 842166X; GW 842166. Grades: >98%. CAS No. 666260-75-9. Molecular formula: C18H17Cl2F3N4O2. Mole weight: 449.25. | |
| GW843682X | GW843682X is a cell-permeable thiophene-benzimidazole compound that acts a selective PLK1 and PLK3 inhibitor with IC50s of 2.2 nM(PLK1) and 9.1 nM(PLK3). Uses: A polo-like kinase-1 (plk1) and polo-like kinase-3 (plk3) inhibitor. Synonyms: GW843682X; GW 843682X; GW-843682X. 5- (5, 6-dimethoxybenzimidazol-1-yl) -3-[[2- (trifluoromethyl) phenyl]methoxy]thiophene-2-carboxamide; Polo-like Kinase Inhibitor III. Grades: ≥98%. CAS No. 660868-91-7. Molecular formula: C22H18F3N3O4S. Mole weight: 477.46. | |
| GW 848687X | GW 848687X is a potent and selective antagonist of EP1 receptor (IC50 = 2.5 nM). GW 848687X displays >400-fold selectivity for EP1 relative to the other EP receptor subtypes, the PGD2 receptor, DP1, and the prostacyclin receptor, IP. Synonyms: 6-[2-[5-chloro-2-[(2,4-digluorophenyl)methoxy]phenyl]-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid. Grades: ≥98%. CAS No. 612831-24-0. Molecular formula: C24H18ClF2NO3. Mole weight: 441.9. | |
| GW-870086 | GW-870086 is a glucocorticoid receptor agonist with a pIC50 of 10.1 in A549 cells expressing NF-κB. It can be used as an anti-inflammatory agent. Synonyms: GW-870086; GW-870086X; 870086; GW870086; GW870086X; GW 870086; GW 870086X. CAS No. 827319-43-7. Molecular formula: C31H39F2NO6. Mole weight: 559.651. | |
| GW9508 | GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, and stimulates insulin secretion in a glucose-sensitive manner. GW9508 is commonly used in the treatment of type 2 diabetes. Synonyms: GW9508; GW-9508; GW 9508; 3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acid. Grades: > 98%. CAS No. 885101-89-3. Molecular formula: C22H21NO3. Mole weight: 347.414. | |
| GW9508 | GW9508. Group: Biochemicals. Alternative Names: 4- [ [ (3-Phenoxyphenyl) methyl] amino] benzenepropanoic Acid. Grades: Highly Purified. CAS No. 885101-89-3. Pack Sizes: 5mg. Molecular Formula: C22H21NO3, Molecular Weight: 347.41. US Biological Life Sciences. | Worldwide |
| GW 9578 | GW 9578 is a potent agonist of PPARα, which is highly selective for PPARα compared to PPARγ and PPAR&delta. Synonyms: 2- [ [4- [2- [ [ [ (2, 4-difluorophenyl) amino] carbonyl] heptylamino] ethyl] phenyl] thio] -2-methyl-propanoic acid. Grades: ≥98%. CAS No. 247923-29-1. Molecular formula: C26H34F2N2O3S. Mole weight: 492.6. | |
| GW 9662 | GW 9662. Group: Biochemicals. Grades: Purified. CAS No. 22978-25-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GW 9662 (2-Chloro-5-nitrobenzanilide) | A potent, selective and irreversible PPARγ antagonist. Blocks the PPARγ-induced differentiation of monocytes to osteoclasts by > 90% at a dose of 0.1uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 22978-25-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| GW-9820 | GW-9820 is a PPAR-gamma agonist with potential antidiabetic effect. Synonyms: 2-[4-[2-[(4-fluorophenyl)carbamoyl-heptylamino]ethyl]phenoxy]-2-methylpropanoic acid; GW-9820; GW 9820; GW9820. Grades: >98%. CAS No. 195131-60-3. Molecular formula: C26H35FN2O4. Mole weight: 458.57. | |
| GX15-070, BCl-2 Inhibitor ((Z)-2-(2-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole Methanesulfonate) | Cell-permeable. A small molecule pan-Bcl-2 antagonist that mimics BH3-only proteins by binding to multiple antiapoptotic Bcl-2 members. GX15-070 has been shown to overcome Bcl-2-, Bcl-xl-, Bcl-w-, and Mcl-1-mediated resistance to Bax or Bak. It potently interferes with the direct interaction between Mcl-1 and Bak in intact outer mitochondrial membrane and inhibits the association between Mcl-1 and Bak in intact cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 803712-79-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| GX-674 | GX-674 is a Nav1.7 antagonist in the aryl sulfonamide class with higher selectivity for Nav1.7 (IC50= 0.1nM) over other Nav subtypes. Nav1.7 is commonly expressed in olfactory epithelium, sympathetic ganglion, and dorsal root ganglion sensory neurons. GX-674 has the potential to alleviate extreme pains. Synonyms: GX-674; GX674;GX 674; 4-(2-(2-Amino-1H-benzo[d]imidazol-5-yl)-4-chlorophenoxy)-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide. CAS No. 1432913-36-4. Molecular formula: C21H13ClF2N6O3S2. Mole weight: 534.94. | |
| GXpep-3 | GXpep-3 is a novel polypeptide inhibitor of phospholipid hydroperoxidase glutathione peroxidase (GPX4). Currently GPX4 is found to be a target which selectively induces iron-dependent cell death (ferroptosis) in cancer cells that express mutant Ras. GXpep-3 is promisingly developed to be a antitumor drug. Uses: Antitumor. Synonyms: GXpep 3; GXpep3. | |
| Gyki 13324 | GYKI-13324 is bifunctional nitrosoureido derivative and alkylating agent. It can produce long-term or total regression of adenomatous, but only marginal growth delay of mucinous tumors. GYKI-13324, seems to be a candidate in the clinical management of colorectal tumors. Uses: Colorectal tumor. Synonyms: GYKI-13324; GYKI 13324; GYKI13324. N- (2-Chloroethyl) -N'- (4- ( ( ( (2-chloroethyl) amino) carbonyl) nitrosamino) -2, 3-dihydroxybutyl) -N-nitrosourea. Grades: 98%. CAS No. 76123-41-6. Molecular formula: C10H18Cl2N6O6. Mole weight: 389.19. | |
| GYKI-13380 | GYKI-13380is a bio-active compound. But no detailed information has been published ye. Synonyms: GYKI-13380; GYKI 13380; GYKI13380; LS-79445; LS 79445; LS79445. 4-((3-(Cyclopentyloxy)-4-methoxyphenyl)methyl)-2-imidazolidinone. Grades: 98%. CAS No. 75614-09-4. Molecular formula: C16H22N2O3. Mole weight: 290.36. | |
| GYKI 14166 | Efegatran is a thrombin inhibitor under the development of Eli Lilly. It can be used for the treatment of thromboembolic disorders. No development reported was reported for the treatment of Thrombosis. Uses: Thrombosis. Synonyms: Efegatran; RGH 2958; LY 294468; GYKI 14166; RGH2958; LY294468; GYKI14166; RGH-2958; LY-294468; GYKI-14166; (S)-1-(D-phenylalanyl)-N-((S)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide sulfate. Grades: 98%. CAS No. 83997-16-4. Molecular formula: C20H30N6O3.H2O4S. Mole weight: 500.57. | |
| GYKI14451 | GYKI14451 is a synthetic tripeptide inhibitor of thrombin. It has anti-atherosclerotic activity. Uses: Gyki14451 has anti-atherosclerotic activity. Synonyms: GYKI-14451; GYKI14451; LY-178207; GYKI 14451;LY 178207; LY178207;Boc-D-Phe-Pro-Arg-H;Tert-butyl ((R)-1-((S)-2-(((S)-5-guanidino-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate. Grades: 98%. CAS No. 69201-89-4. Molecular formula: C25H38N6O5. Mole weight: 502.61. | |
| GYKI-14451 sulfate | GYKI-14451 is a synthetic tripeptide inhibitor of thrombin.It has anti-atherosclerotic activity. Uses: Thrombosis. Synonyms: GYKI-14451 sulfate; GYKI 14451 sulfate; GYKI14451 sulfate; tert-butyl ((R)-1-((S)-2-(((S)-5-guanidino-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate hemisulfate; LY 178207; LY178207; LY-178207; Boc-D-Phe-Pro-Arg-H;69201-89-4 (free base). Grades: 98%. CAS No. 83861-29-4. Molecular formula: C50H76N12O10.H2O4S. Mole weight: 1103.30. | |
| GYKI-16084 | GYKI-16084 is a postsynaptic alpha2-blocker with the potential to treat benign prostatic hyperplasia. Synonyms: 2-[3-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methylamino]propyl]pyridazin-3-one; GYKI16084; GYKI 16084; GYKI-16084R-2-(3-N-(2-benzo(1,4)dioxanylmethyl)-amino-1-propyl)-3(2H)-pyridazinone hydrochloride. Grades: >98%. CAS No. 185739-21-3. Molecular formula: C16H19N3O3. Mole weight: 301.346. | |
| GYKI-16638 | GYKI-16638 is Potassium channel and Sodium channel antagonist originated by Nonindustrial source. It is a novel antiarrhythmic agent. Uses: Arrhythmias. Synonyms: GYKI-16638; GYKI 16638; GYKI16638; N- (4- (2- ( (1- (2, 6-dimethoxyphenoxy) propan-2-yl) (methyl) amino) ethyl) phenyl) methanesulfonamide. Grades: 98%. CAS No. 778564-77-5. Molecular formula: C21H30N2O5S. Mole weight: 422.54. | |
| GYKI-16638 HCl | GYKI-16638 is a novel antiarrhythmic agent, shows combined Class IB and Class III antiarrhythmic properties, resembling the electrophysiological manifestation seen after chronic amiodarone treatment. Uses: A novel antiarrhythmic agent. Synonyms: GYKI-16638 HCl; GYKI 16638 HCl; GYKI16638 HCl; N- [4- [2- [1- (2, 6-dimethoxyphenoxy) propan-2-yl-methylamino] ethyl] phenyl] methanesulfonamide; hydrochloride. Grades: ≥98%. CAS No. 307556-59-8. Molecular formula: C21H31ClN2O5S. Mole weight: 458.998. | |
| GYKI-20238 | GYKI-20238 is a thiazolidine compound with anti-amnesic activity. Uses: Anti-amnesic. Synonyms: GYKI-20238; GYKI20238; GYKI 20238; GYKI-20,238; GYKI20,238; GYKI 20,238. 2-Methylimino-3-(2,6-dichlorophenyl)-4-methylthiazolidine. Grades: ≥96%. CAS No. 30725-74-7. Molecular formula: C11H12Cl2N2S. Mole weight: 274.01. | |
| GYKI-23107 | GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine; GYKI-23107; GYKI 23107; GYKI23107. Grades: 98%. CAS No. 83843-49-6. Molecular formula: C13H22N2. Mole weight: 206.33. | |
| GYKI-23107 dihydrochloride | GYKI-23107 is an antiarrhythmic agent with local anaesthetic activity. Uses: Antiarrhythmic agent. Synonyms: GYKI-23107 dihydrochloride; GYKI 23107 dihydrochloride; GYKI23107 dihydrochloride; 83843-49-6 (free base);N1-(2,6-dimethylphenyl)-N2,N2-dimethylpropane-1,2-diamine dihydrochloride. Grades: 98%. CAS No. 83843-39-4. Molecular formula: C13H24Cl2N2. Mole weight: 279.25. | |
| GYKI-46903 HCl | GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron binding to rat cerebral cortex membranes were 6.91. No development was reported for the treatment of Cognition disorders, Nausea and vomiting. Uses: Cognition disorders; nausea and vomiting. Synonyms: GYKI-46903; GYKI 46903; GYKI46903; GYKI-46,903; GYKI 46,903; GYKI46,903; (4R,5R)-6-(4-fluorophenyl)-1-azabicyclo[3.3.1]non-6-en-4-yl propionate hydrochloride. Grades: 98%. CAS No. 142999-59-5. Molecular formula: C17H21ClFNO2. Mole weight: 325.81. | |
| GYKI-47261 | GYKI-47261 is a non-competitive AMPA receptor antagonist (IC50 = 2.5 μM) and a CYP2E1 inducer. GYKI-47261 shows broad spectrum anticonvulsive activity and neuroprotective effects in vivo. Synonyms: 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline; GYKI 47261; GYKI47261; GYKI-47261. Grades: >99 %. CAS No. 220445-20-5. Molecular formula: C18H15ClN4. Mole weight: 322.796. | |
| GYKI 47261 dihydrochloride | This active molecular is Non-competitiv a AMPA antagonist with IC50 value of 2.5 μM. GYKI-47261 is also a CYP2E1 inducer. GYKI-47261 showed broad spectrum of anticonvulsive and really good neuroprotective effect in vivo. AMPA and NMDA receptors have been implicated in the regulation of corticostriatal synaptic efficacy which abundantly expressed on striatal medium spiny neurons. In 2000, preclinical development for Epilepsy in Hungar was on-going, but no development was reported yet. Uses: Epilepsy; parkinson's disease; stroke. Synonyms: GYKI 47261 dihydrochloride; GYKI47261 dihydrochloride; GYKI-47261 dihydrochloride; 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline;dihydrochloride;220445-20-5 (free base). Grades: 98%. CAS No. 1217049-32-5. Molecular formula: C18H17Cl3N4. Mole weight: 395.71. | |
| GYKI 47261 dihydrochloride | GYKI 47261 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1217049-32-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYKI-52466 | GYKI-52466 is a non-competitive AMPA receptor antagonist. It belongs to 2,3-benzodiazepine that acts as an ionotropic glutamate receptor antagonist. It has anticonvulsant and neuroprotective properties. It is an orally-active anticonvulsant and skeletal muscle relaxant. It also was found to have therapeutic potential for cocaine addiction treatment. Uses: Gyki-52466 is an orally-active anticonvulsant and skeletal muscle relaxant. it also was found to have therapeutic potential for cocaine addiction treatment. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline;GYKI-52466; GYKI52466; GYKI 52466; GYKI-5,2466; GYKI52,466; GYKI 52,466. Grades: >99 %. CAS No. 102771-26-6. Molecular formula: C17H15N3O2. Mole weight: 293.33. | |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride is an orally active, highly selective and noncompetitive AMPA/kainate receptor antagonist with the IC 50 values of 7.5 and 11μM, respectively. GYKI 52466 dihydrochloride has good blood brain barrier permeability and anticonvulsant effect. GYKI 52466 dihydrochloride can be used in Parkinson's disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2319722-40-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103234A. | |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 102771-26-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYKI 52466 Hydrochloride (1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride, GYKI-52,466, GYK I52466) | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 10-20uM) over kainate (IC50 ~450uM) and nMDA (IC50 >> 50uM) receptors. Commonly used as neuroprotectant, anticonvulsant, and skeletal muscle relaxant. Biologically viable admitted orally or systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 102771-26-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GYKI 53655 | GYKI 53655 is a selective AMPA receptor antagonist with anticonvulsant activity. Synonyms: GYKI 53655; GYKI53655; GYKI-53655; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide. Grades: 99%. CAS No. 143692-18-6. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| GYKI 53655 hydrochloride | GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist displaying anticonvulsant activity. It also acts as a blocker of GluK3 homomeric receptors (IC50 = 63 μM) and GluK2b(R)/GluK3 heteroreceptors (IC50 = 32 μM) at high concentrations. GYKI 53655 prolongs the survival time after MgCl2- induced global cerebral ischemia. Synonyms: GYKI53655 Hydrochloride; GYKI53655 HCl; GYKI53655; GYKI 53655; GYKI-53655. LY 300168 hydrochloride; LY300168 hydrochloride; LY-300168 hydrochloride; 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 143692-48-2. Molecular formula: C19H20N4O3.HCl. Mole weight: 388.85. | |
| GYKI 53655 hydrochloride | GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid ( AMPA ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY300168 hydrochloride. CAS No. 143692-48-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103228. | |
| GYKI 53655 Hydrochloride | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 6 and 5uM for GluA1 and GluA4, respectively) over kainate receptors (IC50 = 63 and 32uM for GluK3 and GluK2b/GluK3 receptors. Used as neuroprotectant and anticonvulsant, and a valuable tool for the study of AMPA receptor-mediated processes in vivo. Group: Biochemicals. Alternative Names: LY 300168, GYKI-53655 Hydrochloride, AMPA Glutamate Receptor Antagonist, GYKI 53655 Hydrochloride, 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride. Grades: Highly Purified. CAS No. 143692-48-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GYKI 53784 | GYKI-53784, a dioxolbenzene derivative, has been found to be a AMPA receptor antagonist that could block excitotoxicity and decrease auditory nerve activity at some extent. Synonyms: GYKI-53784; GYKI53784; GYKI 53784; LY 303070; LY-303070; LY303070; 7H-1,3-Dioxolo(4,5-h)(2,3)benzodiazepine-7-carboxamide, 8,9-dihydro-5-(4-aminophenyl)-N,8-dimethyl-, (R)-; UNII-91N8O25H4L; AC1MIO7T. Grades: 98%. CAS No. 161832-71-9. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| Gymnema Extract (Ratio) | Gymnema Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gymnema Extract (Ratio). Cat No: EXTW-070. |  |
| Gymnema Extract (Standard) | Gymnema (Gymnema sylvestre) is an herb native to the tropical forests of southern and central India and Sri Lanka. Applications: Gymnema extract is one of the major botanicals being administered for those suffering from diabetes, in boosting insulin levels and controlling healthy blood sugar levels. it has unique property to directly mask the tongue's ability to taste sweet foods, at the same time suppresses glucose absorption from the intestine. Group: Others. CAS No. 122168-40-5. Purity: 25.0% 75.0% Gymnemic acid HPLC. Mole weight: 806.445257 g/mol. Gymnema Extract (Standard); 122168-40-5; C43H66O14. Cat No: EXTW-004. | |
| Gymnemagenin | Gymnemagenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 22467-07-8. Pack Sizes: 10mg. Molecular Formula: C30H50O6, Molecular Weight: 506.72. US Biological Life Sciences. | Worldwide |
| Gymnema Sylvestre Extract | Gymnema Sylvestre Extract. Applications: Used for health care products, dietary supplements, reduce hypoglycemic activity. Group: Others. Synonyms: Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult. CAS No. 1399-64-0. Purity: 25%, 75% Gymnemic Acid By UV. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Gymnema sylvestre ?Retz.? Schult. Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-098. | |
| Gymnema Sylvestre Extract 75% | Gymnema Sylvestre Extract 75%. |  CA, FL & NJ |
| Gymnemic acid | Gymnemic acid Inhibitor. Uses: Scientific use. Product Category: TN1718. CAS No. 122168-40-5. |  |
| Gymnemic acid I | Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I decreases the apoptosis under the high glucose stress [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 122168-40-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2541. | |
| Gymnemic Acid I | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 122168-40-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Gymnemic Acid I | Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I decreases the apoptosis under the high glucose stress. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 122168-40-5. Molecular formula: C43H66O14. Mole weight: 806.97. Purity: 0.98. IUPACName: (2S,3S,4S,5R,6R)-6-[[(3S,4R,4aR,6aR,6bS,8S,8aR,9R,10R,12aS,14aR,14bR)-8a-(acetyloxymethyl)-8,9-dihydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid. Canonical SMILES: CC=C(C)C(=O)OC1C(C2(C(CC1(C)C)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)OC6C(C(C(C(O6)C(=O)O)O)O)O)C)COC(=O)C)O. Product ID: ACM122168405. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Gymnestrogenin | Gymnestrogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19942-02-0. Pack Sizes: 5mg. Molecular Formula: C30H50O5, Molecular Weight: 490.73. US Biological Life Sciences. | Worldwide |
| Gymnestrogenin | Gymnestrogenin is a triterpenoid compound found in the Gymnema sylvestre. with dual LXRα/β antagonistic property. Synonyms: (3S, 4aS, 5S, 6aR, 6aS, 6bR, 8aR, 9R, 10S, 12aR, 14bS)-4a, 9-bis(hydroxymethyl)-2, 2, 6a, 6b, 9, 12a-hexamethyl-1, 3, 4, 5, 6, 6a, 7, 8, 8a, 10, 11, 12, 13, 14b-tetradecahydropicene-3, 5, 10-triol. Grades: >98%. CAS No. 19942-02-0. Molecular formula: C30H50O5. Mole weight: 490.725. | |
| Gymnin | Gymnin is a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill). Gymnin exerts antifungal activity against F.oxysporum and M.arachidicola, with an IC50 of 2 μM for the former fungus and 10 μM, respectively. It inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase. | |
| Gynostemma Extract | Gynostemma extract is prepared from the leaf of Gynostemma, a cucurbitaceous plant belongs to perennial grass nature lianas grows in the southeastern regions of China. Gynostemma pentaphyllum extract contains more than 80 different saponins, so is also known as southern ginseng. Gynostemma extract gypenoside is widely used as an anti aging supplement, or a tonic to treat bronchitis, strengthen the body, reduce fatigue, and reinforce overall health. Group: Others. Gynostemma Extract; Gynostemma Pentaphyllum Thunb. Cat No: EXTC-023. | |
| Gynostemma Extract | Gynostemma Extract (Ginsenoside C-Mx1) is a natural product. Uses: Scientific research. Group: Natural products. Alternative Names: Ginsenoside C-Mx1; Gypenoside IX. CAS No. 80321-63-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0167. | |
| gynostemma pentaphylla extractive | Anti-cancer: on liver cancer, lung cancer, metrocarcinoma, melanotic sarcoma; Anti-aging and improving immunity; Reducing blood fat; Prevent side-effect of glucocorticoid. Uses: Designed for use in research and industrial production. Product Category: Material of health food. Appearance: light yellow grown powder. CAS No. 15588-68-8. Molecular formula: C80H126O44. Mole weight: 1791.83. Product ID: ACM15588688. Alfa Chemistry ISO 9001:2015 Certified. | |
| Gynostemma Pentaphyllum Extract (Ratio) | Gynostemma Pentaphyllum Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gynostemma Pentaphyllum Extract (Ratio). Cat No: EXTW-037. | |
| Gypenoside I | Gypenoside I is an intricate phytochemical abundantly occurring in the plant known as Gynostemma Pentaphyllum. The multifaceted potential of Gypenoside I resides in its astonishingly promising capacity to potentially study a diverse array of maladies, which encompass the realms of cancer, diabetes, inflammation, as well as cardiovascular disorders. CAS No. 85889-20-9. Molecular formula: C46H78O18. Mole weight: 919.1. | |
| Gypenoside XLIX | Gypenoside XLIX. Group: Biochemicals. Grades: Plant Grade. CAS No. 94987-08-3. Pack Sizes: 20mg. Molecular Formula: C52H86O21, Molecular Weight: 1047.23. US Biological Life Sciences. | Worldwide |
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