A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products ( IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin ), modulation of cell cycle proteins ( cyclin D1 and c-Myc ), activation of caspases and JNK , inhibition of Akt [1]. Guggulsterone, a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC 50 s of 17 and 15 μM for Z- and E-Guggulsterone, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Z/E-Guggulsterone. CAS No. 95975-55-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107738.
Guggulsterone
Guggulsterone. Group: Biochemicals. Grades: Purified. CAS No. 95975-55-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Guggulsterone E&Z
Guggulsterone E&Z. Group: Biochemicals. Alternative Names: (E&Z)-Guggulsterone. Grades: Plant Grade. CAS No. 95975-55-6. Pack Sizes: 20mg. Molecular Formula: C21H28O2, Molecular Weight: 312.446. US Biological Life Sciences.
Worldwide
Guggulsterone Z
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Guiaphenesin
Guiaphenesin. Group: Biochemicals. Grades: Highly Purified. CAS No. 93-14-1. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C10H14O4. US Biological Life Sciences.
Worldwide
Guinea Green B
Guinea Green B. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Gulonolactone
Gulonolactone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Gulonolactone, D-galactonolactone, D-Gulono gamma-lactone, D-Gulono-1,4-lactone, Gulonic acid-1,4-lactone, Gulonic acid, gamma-lactone, D-Gulonic acid gamma-lactone, D-(-)-Gulono-1,4-lactone, 219355_ALDRICH, STOCK1N-51779, MolPort-002-525-586, CID165105, ZINC00901647, BAF290D4-5A2B-424C-9F26-37DBB214E76B, 3327-64-8. Appearance: Off white powder. CAS No. 3327-64-8. Molecular formula: C6H10O6. Mole weight: 178.14. Purity: RG. IUPACName: (3R,4S,5S)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one. Product ID: ACM3327648. Alfa Chemistry ISO 9001:2015 Certified.
guluronate-specific alginate lyase
The enzyme catalyses the degradation of alginate by a β-elimination reaction. It cleaves the (1?4) bond between α-L-guluronate and either α-L-guluronate or β-D-mannuronate, generating oligosaccharides with 4-deoxy-α-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and α-L-guluronate at the reducing end. Depending on the composition of the substrate, the enzyme produces oligosaccharides ranging from two to six residues, with preference for shorter products. cf. EC 4.2.2.3, mannuronate-specific alginate lyase. Group: Enzymes. Synonyms: alginase II; guluronate lyase; L-guluronan lyase; L-guluronate lyase; poly-α-L-guluronate lyase; polyguluronate-specific alginate lyase; poly(α-L-1,4-guluronide) exo-lyase; poly(α-L-guluro. Enzyme Commission Number: EC 4.2.2.11. CAS No. 64177-88-4. Poly α-guluronate lyase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5086; guluronate-specific alginate lyase; EC 4.2.2.11; 64177-88-4; alginase II; guluronate lyase; L-guluronan lyase; L-guluronate lyase; poly-α-L-guluronate lyase; polyguluronate-specific alginate lyase; poly(α-L-1,4-guluronide) exo-lyase; poly(α-L-guluronate) lyase; poly[(1?4)-α-L-guluronide] exo-lyase. Cat No: EXWM-5086.
Gum acacia
Gum acacia. Group: Biochemicals. Grades: Highly Purified. CAS No. 9000-1-5. Pack Sizes: 250g, 500g, 1Kg, 2Kg, 5Kg. Molecular Formula: C12H7ClN2O3. US Biological Life Sciences.
Worldwide
Gum arabic
100g Pack Size. Group: Biochemicals. Formula: N/A. CAS No. 9000-1-5. Prepack ID 13599707-100g. See USA prepack pricing.
Gum arabic
Gum Arabic (Arabic gum) is a branched-chain, complex polysaccharide derive from A. Senegal. Gum Arabic is an anti-oxidant, and can protect against experimental hepatic-, renal- and cardiac toxicities. Gum Arabic also can be used in immunohistochemistry [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Arabic gum. CAS No. 9000-1-5. Pack Sizes: 10 g; 25 g. Product ID: HY-N6664.
Gum arabic
Cas No. 9000-1-5.
Gum arabic
500g Pack Size. Group: Biochemicals. Formula: N/A. CAS No. 9000-1-5. Prepack ID 13599707-500g. See USA prepack pricing.
Gum Arabic, Laboratory Grade, 100g
Characteristic: Buff colored. Storage Code: Green; general chemical storage. Alternative Names: Acacia. Grades: chem-grade laboratory. CAS No. 9000-01-5. Product ID: 866108. -- SOLD FOR EDUCATIONAL USE ONLY --
Gum cassia tora
Gum guaiac
Polysaccharide. Uses: For analytical and research use. Group: Reagents. CAS No. 9000-29-7. Pack Sizes: 1KG.
G/U Mismatch-Specific DNA Glycosylase from E.coli, Recombinant
G/U mismatch-specific DNA glycosylase (mug) is a part of the TDG/mug DNA glycosylase family. Mug is necessary for DNA damage lesion repair in stationary-phase cells. Mug protein removes three N4-ethenocytosine and takes away s the uracil base from mismatches in the order of U:G>U:A. The enzyme Uracil-N-Glycosylase removes uracil from the DNA leaving an AP position. Mug is also able to hydrolyzing the carbon-nitrogen bond among the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine plays a role in substrate recognition. Group: Enzymes. Synonyms: Xanthine DNA glycosylase; dug; ECK3058; JW3040; ygjF; G/U mismatch-specific DNA glycosylase; Double-strand-specific uracil glycosylase; Mismatch-specific uracil DNA-glycosylase; mug. Enzyme Commission Number: EC 3.2.2.28. Purity: Greater than 90% as determined by SDS-PAGE. MUG. Mole weight: 21.1 kDa. Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. Form: Sterile Filtered colorless solution. Source: E.coli. Species: E.coli. Cat No: NATE-1911.
Gum karaya
Gum Karaya is a vegetable gum produced from the exudate of the sterculia trees. Gum Karaya is an acidic polysaccharide composed of galactose, rhamnose and galacturonic acid. It is used in food as a thickener and emulsifier, and as a laxative and denture binder. Synonyms: Sterculia gum; Gum Sterculia; Indian gum tragacanth. CAS No. 9000-36-6.
Gum Mastic
Gum Mastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 61789-92-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Gum Rosin
Gum Rosin and its derivatives can be used as microencapsulating materials, film forming agents, and binding agents in formulation of tablets. They are also used in the formulation of cosmetics and the bases of chewing gum. Gum Rosin extracts are also commonly used to treat burns. Group: Biochemicals. Grades: Highly Purified. CAS No. 8050-9-7. Pack Sizes: 10g, 25g. Molecular Formula: N/A, Molecular Weight: US Biological Life Sciences.
Worldwide
Gum Rosin
Gum Rosin. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers.
Gum Sandarac
Gum Sandarac
Gum tragacanth
Gum Tragacanth is the exudate gum of astragalus trees grown mainly in Iran and Turkey. As an effective emulsifier and thickener, Tragacanth has been widely used in food and pharmaceutical industry. Uses: Cathartics; excipients. Synonyms: Tragacanth; YT31961. Molecular formula: C10H30. Mole weight: 150.35.
Gum tragacanth
100g Pack Size. Group: Biochemicals, Carbohydrates, Flavours and Fragrance Materials. Formula: N/A. CAS No. 9000-65-1. Prepack ID 38835433-100g. See USA prepack pricing.
Gum Turpentine
Gum Turpentine. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
California
GUN35901
GUN35901 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. GUN35901 is a demethyl analogue of DUN99845 (CAT#556012). GUN35901 was first reported in patent CN 112057443. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GUN35901; GUN-35901; GUN 35901; SN-011; SN011; SN 011. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2249435-90-1. Molecular formula: C25H19FN2O4S. Mole weight: 462.5. Purity: >98%. IUPACName: N-(3-((4-fluorophenyl)sulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide. Product ID: ACM2249435901. Alfa Chemistry ISO 9001:2015 Certified.
Gunacin
It is produced by the strain of Ustilago sp. It is a quinone antibiotic. It has strong activity against gram-positive bacteria, negative bacteria and mycoplasma. Synonyms: 2H-Naphtho(2,3-b)pyran-5,10-dione, 3,4-dihydro-4-(acetyloxy)-3,6-dihydroxy-8-methoxy-2-methyl-. Grades: 95%. CAS No. 73341-70-5. Molecular formula: C17H16O8. Mole weight: 348.33.
Gunagratinib
Gunagratinib is a tyrosine kinase inhibitor, with antineoplastic activity. Synonyms: 3-[(3,5-dimethoxyphenyl)ethynyl]-5-(methylamino)-1-[(3S)-1-(prop-2-enoyl)pyrrolidin-3-yl]-1H-pyrazole-4-carboxamide; (S)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1H-pyrazole-4-carboxamide. CAS No. 2211082-53-8. Molecular formula: C22H25N5O4. Mole weight: 423.47.
Gurjum balsam
Gurjum balsam. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Gurjum balsam;Gurjum balsam rectified. Product Category: Heterocyclic Organic Compound. CAS No. 8030-55-5. Product ID: ACM8030555. Alfa Chemistry ISO 9001:2015 Certified. Categories: Gurjun balsam.
Gurjun Dark - Copaene
The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%). Uses: Fragrance. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-001. Olfactive Profile: Balsamic, woody, sweet, greasy, pepper. EC No: 232-444-8. Origin: Indonesia.
New Jersey
Gurjun Dark - Gurjunene
"The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%)". Uses: Fragrance. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-003. Olfactive Profile: Balsamic, woody, sweet. EC No: 232-444-8. Origin: Malaysia.
New Jersey
Gurjunene 85%+
"The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents". Uses: Fragrances, Cosmetics. Group: Plant Extracts. INCI Names: Gurjunene. Grades: INDUSTRIAL GRADE. CAS No. 489-40-7. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-005. Olfactive Profile: Balsamic, woody, sweet. EC No: 207-695-1. Origin: Malaysia.
New Jersey
Gurjun Light - Copaene
The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%). Uses: Fragrance Products. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-002. Olfactive Profile: Balsamic, woody, sweet, greasy, pepper. EC No: 232-444-8. Origin: Indonesia.
New Jersey
Gurjun Light - Gurjunene
The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%). Uses: Fragrance Products. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-004. Olfactive Profile: Balsamic, woody, earthy and warm. EC No: 232-444-8. Origin: Malaysia.
New Jersey
guselkumab
guselkumab is a selectively blocking agent for interleukin-23 (IL-23), a cytokine involved in plaque psoriasis. guselkumab was approved by FDA as an anti-inflammatory drug for the treatment of moderate to severe plaque psoriasis. Uses: Anti-inflammatory drug. Synonyms: Tremfya. CAS No. 1350289-85-8. Molecular formula: C6402H9864N1676O1994S42. Mole weight: 143.6.
Guselkumab
Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with K d values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO 1959. CAS No. 1350289-85-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9931.
Gusperimus
Gusperimus is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells; this agent may suppress growth of certain T-cell leukemia cell lines. Uses: Immunosuppressive agents. Synonyms: deoxyspergualin; Deoxyspergualin Hydrochloride; Gusperimus Trihydrochloride; BMS-181173; BMS181173; BMS 181173; BMY-42215-1; BMY 42215 1; NKT-01; NKT 01; NKT01. CAS No. 104317-84-2. Molecular formula: C17H37N7O3. Mole weight: 387.52.
Gusperimus trihydrochloride
Gusperimus is a derivative of the anti-tumor antibiotic spergualin, which has immunosuppressive activity. Synonyms: Spanidin; NKT-01. Grades: 98%. CAS No. 85468-01-5. Molecular formula: C17H37N7O3.3HCl. Mole weight: 496.91.
Gusperimus Trihydrochloride
Gusperimus Trihydrochloride is an immunosuppressive agent, which was effective both in preventing and treating graft-vs.-host disease in mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 85468-01-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H37N7O3; 3(HCl), Molecular Weight: 387.523364599999. US Biological Life Sciences.
Worldwide
Gut Microbial Metabolite Library
A unique collection of 352 gut microbial metabolites which can be used for HTS and HCS. Uses: Scientific use. Product Category: L2540. Categories: Gut Microbial Metabolite Libraries.
Guvacine hydrochloride
Guvacine hydrochloride is an alkaloid from the nut of Areca catechu , acts as an inhibitor of GABA transporter , and dispalys modest selectivity for cloned GABA transporters with IC 50 s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3). Uses: Scientific research. Group: Natural products. CAS No. 6027-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-100809.
Guvacine hydrochloride is a specific GABA uptake inhibitor (IC50 = 14, 58, 119 and 1870 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1, respectively). Guvacine may be beneficial for the treatment of neuropsychiatric disorders. Synonyms: 1,2,5,6-Tetrahydropyridine-3-carboxylic acid hydrochloride. Grades: ≥99% by HPLC. CAS No. 6027-91-4. Molecular formula: C6H9NO2.HCl. Mole weight: 163.6.
Guvacine Hydrochloride
A GABA uptake inhibitor. It is used for the treatment of neurodegenerative diseases. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Hydrochloride; 1,2,5,6-Tetrahydro-. Grades: Highly Purified. CAS No. 6027-91-4. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Guvacine hydrochloride >96% \ gaba uptak
Guvacine hydrochloride >96% \ gaba uptak. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Guvacine hydrochloride, 6027-91-4, 1,2,5,6-tetrahydropyridine-3-carboxylic acid hydrochloride, 498-96-4, 1,2,5,6-Tetrahydronicotinic acid, Guvacine HCl, AGN-PC-00IQSI, Ambcb4141599, SureCN1057880, G007_SIGMA, MLS000859975, SPECTRUM1502126, CHEMBL1256362, CTK7I6002, MolPort-003-665-602, ANW-67778, CCG-38871, AKOS015849631, AG-A-09676, AG-G-15681. Product Category: Heterocyclic Organic Compound. CAS No. 6027-91-4. Molecular formula: C6H9NO2HCl. Mole weight: 163.6. Purity: 0.96. IUPACName: 1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydrochloride. Canonical SMILES: C1CNCC(=C1)C(=O)O.Cl. Product ID: ACM6027914. Alfa Chemistry ISO 9001:2015 Certified.
Guvacoline hydrobromide
Guvacoline hydrobromide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GUVACINE METHYL ESTER, HYDROBROMIDE;GUVACOLINE, HYDROBROMIDE;NORARECOLINE;Norarecoline, Guvacine Methyl Ester, Hydrobromide,;1,2,5,6-Tetrahydro-3-pyridinecarboxylic acid methyl ester;1,2,3,6-tetrahydropyridine-5-carboxylic acid methyl ester;methyl 1,2,3. Product Category: Heterocyclic Organic Compound. Appearance: Crystalline Solid. CAS No. 495-19-2. Molecular formula: C7H12BrNO2. Mole weight: 222.08. Product ID: ACM495192. Alfa Chemistry ISO 9001:2015 Certified.
Guvacoline hydrobromide
Guvacoline hydrobromide. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-3-pyridinecarboxylic acid methyl ester hydrobromide. Grades: Highly Purified. CAS No. 17210-51-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C7H12BrNO2. US Biological Life Sciences.
A useful tool in the identification of muscarinic receptors. Group: Biochemicals. Alternative Names: Norarecoline, Guvacine Methyl Ester, Hydrobromide. Grades: Highly Purified. CAS No. 17210-51-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Guvacoline hydrochloride
Guvacoline hydrochloride, a pyridine alkaloid found in Areca triandra , can act as a weak full agonist of atrial and ileal muscarinic receptors [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6197-39-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5016.
GV-196771
GV-196771, an indole derivative, has been found to be a non-opioid analgesic agent which is also a NMDA antagonist binds to glycine-binding site and was once studied in pain therapy. Synonyms: GV-196771; GW-196771; GV 196771; GW 196771; GV196771; GW196771; AC1OC7O7; SCHEMBL499308; 4,6-dichloro-3-[(E)-(2-oxo-1-phenylpyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylic acid; GV196771A; GV 196771A; GV-196771A. Grades: 98%. CAS No. 166974-22-7. Molecular formula: C20H14Cl2N2O3. Mole weight: 401.24.
GV-58
GV-58, a pupin derivative, has been found to be a P/Q-type Ca²?-channel agonist that could be used to against neuromuscular weakness. IC50: 7.21/8.81 uM (N-type/P-Q-type Ca2+ channel). Uses: Gv-58 has been found to be a p/q-type ca²?-channel agonist that could be used to against neuromuscular weakness. Synonyms: GV-58; CS-3617; GV 58; CS 3617; GV58; CS3617; CHEMBL2206242; SCHEMBL17628602; BDBM50400564. Grades: 98%. CAS No. 1402821-41-3. Molecular formula: C18H26N6OS. Mole weight: 374.50.
GVK-904 is an inhibitor of Trk-A with high selectivity for wild-type cancers. GVK-904 is a non-ATP-competitive inhibitor. It can be used to treat cancers induced by Trk-A. Uses: Antitumor drug. Synonyms: GVK 904; GVK904.
GW0742
GW0742. Group: Biochemicals. Alternative Names: 4-[[[2-[3-Fluoro-4- (trifluoromethyl) phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy] acetic acid. Grades: Highly Purified. CAS No. 317318-84-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C21H17F4NO3S2. US Biological Life Sciences.
Worldwide
GW0742
GW0742 is a potent PPARβ and PPARδ agonist, with an IC 50 of 1 nM for human PPARδ in binding assay, and EC 50 s of 1 nM, 1.1 μM and 2 μM for human PPARδ , PPARα, and PPARγ, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW610742. CAS No. 317318-84-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13928.
GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPAR&gamma. Synonyms: GW0742; GW-0742; GW 0742; GW0742X; GW-0742X; GW 0742X; GW610742; GW-610742; GW 610742. Grades: >98%. CAS No. 317318-84-6. Molecular formula: C21H17F4NO3S2. Mole weight: 471.49.
A small molecule agonist of the human Peroxisome Proliferator-Activated Recept d (PPAR d). It shows an EC50 of 1.1 nM against PPAR d with 100-fold selectivity over the other human subtypes. Group: Biochemicals. Alternative Names: 4-[[[2-[3-Fluoro-4- (trifluoromethyl) phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy] Acetic Acid. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
GW 1100
GW 1100 is a selective G protein-coupled receptor GPR40 antagonist. GW 1100 has been shown to reverse the effects GPR40 agonists which induce glucose-stimulated insulin secretion. Group: Biochemicals. Alternative Names: 4-[5-[ (2-Ethoxy-5-pyrimidinyl) methyl]-2-[[ (4-fluorophenyl) methyl]thio]-4-oxo-1 (4H) -pyrimidinyl]benzoic Acid Ethyl Ester; 1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone. Grades: Highly Purified. CAS No. 306974-70-9. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
GW-1100
A cell-permeable pyrimidinylmethyl-pyrimidinone compound that acts as potent, reversible and non-competitive GPR40 antagonist. Shown to significantly reverse glucose-induced insulin secretion potentiated by GW9508 and only partially reduce linoleic acid effect in MIN6 cells. Synonyms: GW 1100; GW-1100; GW1100. Grades: >98%. CAS No. 306974-70-9. Molecular formula: C27H25FN4O4S. Mole weight: 520.58.
A cell-permeable pyrimidinylmethyl-pyrimidinone compound that acts as potent, reversible and non-competitive GPR40 antagonist. Selectively blocks GPR40-mediated intracellular Ca2+ release stimulated by GPR40 Agonist GW9508 and linoleic acid (pIC50 of 5.99 in GPR40 expressing HEK293 cells) with no effect on GPR120-mediated activation. Shown to significantly reverse glucose-induced insulin secretion potentiated by GW9508 and only partially reduce linoleic acid effect in MIN6 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 306974-70-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
GW1929
A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays). Synonyms: GW 1929; GW-1929. Grades: >98%. CAS No. 196808-24-9. Molecular formula: C30H29N3O4. Mole weight: 495.57.
GW1929
Potent and subtype-selective (>1000-fold) PPARgamma agonist. Angiogenesis and apoptosis inhibitor. Anti-inflammatory. Anti-hyperglycemic and anti-hyperlipidemic agent. GW1929 is an antidiabetic; the glucose-lowering effect in rats is 100-fold more potent than that of troglitazone. Group: Biochemicals. Alternative Names: N-(2-Benzoylphenyl)-L-tyrosine PPARγ Agonist; (2S) - ( (2-Benzoylphenyl) amino-3- [4- [2- (methylpyridin-2-ylamino) ethoxy] phenyl] propionic acid. Grades: Highly Purified. CAS No. 196808-24-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C30H29N3O4. US Biological Life Sciences.
Worldwide
GW1929 - CAS 196808-24-9
A potent, tyrosine-based peroxisome proliferator-activated receptor ? (PPAR?) agonist (EC?? = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays). Group: Fluorescence/luminescence spectroscopy.
GW 1929 hydrochloride is a selective and orally bioactive agonist of peroxisome proliferator-activated receptor (PPAR)γ (pEC50 = 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors, respectively). GW 1929 causes a decrease of glucose, fatty acid and triglyceride levels following oral administration in vivo. Synonyms: GW 1929 hydrochloride; GW1929 hydrochloride; GW-1929 hydrochloride; N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride; (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1217466-21-1. Molecular formula: C30H29N3O4.HCl. Mole weight: 532.03.