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| Product | Description | |
|---|---|---|
| Gum arabic | 100g Pack Size. Group: Biochemicals. Formula: N/A. CAS No. 9000-1-5. Prepack ID 13599707-100g. See USA prepack pricing. |  |
| Gum arabic | 500g Pack Size. Group: Biochemicals. Formula: N/A. CAS No. 9000-1-5. Prepack ID 13599707-500g. See USA prepack pricing. | |
| Gum arabic | Cas No. 9000-1-5. |  |
| Gum arabic | Gum Arabic (Arabic gum) is a branched-chain, complex polysaccharide derive from A. Senegal. Gum Arabic is an anti-oxidant, and can protect against experimental hepatic-, renal- and cardiac toxicities. Gum Arabic also can be used in immunohistochemistry [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Arabic gum. CAS No. 9000-1-5. Pack Sizes: 10 g; 25 g. Product ID: HY-N6664. |  |
| Gum Arabic, Laboratory Grade, 100g | Characteristic: Buff colored. Storage Code: Green; general chemical storage. Alternative Names: Acacia. Grades: chem-grade laboratory. CAS No. 9000-01-5. Product ID: 866108. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Gum cassia tora | | |
| Gum guaiac | Polysaccharide. Uses: For analytical and research use. Group: Reagents. CAS No. 9000-29-7. Pack Sizes: 1KG. |  |
| GUM GUAIAC | GUM GUAIAC. Group: Polysaccharide. CAS No. 9000-29-7. Mole weight: CAS: 9000-29-7. PURIFIED. |  |
| G/U Mismatch-Specific DNA Glycosylase from E.coli, Recombinant | G/U mismatch-specific DNA glycosylase (mug) is a part of the TDG/mug DNA glycosylase family. Mug is necessary for DNA damage lesion repair in stationary-phase cells. Mug protein removes three N4-ethenocytosine and takes away s the uracil base from mismatches in the order of U:G>U:A. The enzyme Uracil-N-Glycosylase removes uracil from the DNA leaving an AP position. Mug is also able to hydrolyzing the carbon-nitrogen bond among the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine plays a role in substrate recognition. Group: Enzymes. Synonyms: Xanthine DNA glycosylase; dug; ECK3058; JW3040; ygjF; G/U mismatch-specific DNA glycosylase; Double-strand-specific uracil glycosylase; Mismatch-specific uracil DNA-glycosylase; mug. Enzyme Commission Number: EC 3.2.2.28. Purity: Greater than 90% as determined by SDS-PAGE. MUG. Mole weight: 21.1 kDa. Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. Form: Sterile Filtered colorless solution. Source: E.coli. Species: E.coli. Cat No: NATE-1911. |  |
| Gum karaya | Gum Karaya is a vegetable gum produced from the exudate of the sterculia trees. Gum Karaya is an acidic polysaccharide composed of galactose, rhamnose and galacturonic acid. It is used in food as a thickener and emulsifier, and as a laxative and denture binder. Synonyms: Sterculia gum; Gum Sterculia; Indian gum tragacanth. CAS No. 9000-36-6. | |
| Gum Mastic | Gum Mastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 61789-92-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. |  Worldwide |
| Gum Rosin | Gum Rosin and its derivatives can be used as microencapsulating materials, film forming agents, and binding agents in formulation of tablets. They are also used in the formulation of cosmetics and the bases of chewing gum. Gum Rosin extracts are also commonly used to treat burns. Group: Biochemicals. Grades: Highly Purified. CAS No. 8050-9-7. Pack Sizes: 10g, 25g. Molecular Formula: N/A, Molecular Weight: US Biological Life Sciences. | Worldwide |
| Gum Rosin | Gum Rosin. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner. |  California |
| GUM ROSIN | PALE-YELLOW-TO-AMBER FRAGMENTS OR POWDER WITH CHARACTERISTIC ODOUR. Group: Polymers. CAS No. 8050-9-7. Product ID: (4aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylic acid. Molecular formula: 302.5g/mol. Mole weight: C20H30O2. CC (C)C1=CC2=CCC3C (C2CC1) (CCCC3 (C)C (=O)O)C. InChI=1S/C20H30O2/c1-13 (2)14-6-8-16-15 (12-14)7-9-17-19 (16, 3)10-5-11-20 (17, 4)18 (21)22/h7, 12-13, 16-17H, 5-6, 8-11H2, 1-4H3, (H, 21, 22)/t16?, 17?, 19-, 20?/m1/s1. RSWGJHLUYNHPMX-SAOIUIGASA-N. | |
| Gums | Our wide distribution network, with locations coast-to-coast, helps guarantee fast, reliable service to Univar's customers. |  |
| Gum Sandarac | Gum Sandarac |  |
| Gum tragacanth | Gum Tragacanth is the exudate gum of astragalus trees grown mainly in Iran and Turkey. As an effective emulsifier and thickener, Tragacanth has been widely used in food and pharmaceutical industry. Uses: Cathartics; excipients. Synonyms: Tragacanth; YT31961. Molecular formula: C10H30. Mole weight: 150.35. | |
| Gum tragacanth | 100g Pack Size. Group: Biochemicals, Carbohydrates, Flavours and Fragrance Materials. Formula: N/A. CAS No. 9000-65-1. Prepack ID 38835433-100g. See USA prepack pricing. | |
| Gum Turpentine | Gum Turpentine. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner. | California |
| GUN35901 | GUN35901 is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING-mediated disease. GUN35901 is a demethyl analogue of DUN99845 (CAT#556012). GUN35901 was first reported in patent CN 112057443. Group: Inhibitors. Alternative Names: GUN35901; GUN-35901; GUN 35901; SN-011; SN011; SN 011. CAS No. 2249435-90-1. Molecular formula: C25H19FN2O4S. Mole weight: 462.5. Appearance: Solid powder. Purity: >98%. IUPACName: N-(3-((4-fluorophenyl)sulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide. Catalog: ACM2249435901. |  |
| Gunacin | It is produced by the strain of Ustilago sp. It is a quinone antibiotic. It has strong activity against gram-positive bacteria, negative bacteria and mycoplasma. Synonyms: 2H-Naphtho(2,3-b)pyran-5,10-dione, 3,4-dihydro-4-(acetyloxy)-3,6-dihydroxy-8-methoxy-2-methyl-. Grades: 95%. CAS No. 73341-70-5. Molecular formula: C17H16O8. Mole weight: 348.33. | |
| Gunagratinib | Gunagratinib is a tyrosine kinase inhibitor, with antineoplastic activity. Synonyms: 3-[(3,5-dimethoxyphenyl)ethynyl]-5-(methylamino)-1-[(3S)-1-(prop-2-enoyl)pyrrolidin-3-yl]-1H-pyrazole-4-carboxamide; (S)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1H-pyrazole-4-carboxamide. CAS No. 2211082-53-8. Molecular formula: C22H25N5O4. Mole weight: 423.47. | |
| Gurjun Dark - Copaene | The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%). Uses: Fragrance. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-001. Olfactive Profile: Balsamic, woody, sweet, greasy, pepper. EC No: 232-444-8. Origin: Indonesia. |  New Jersey |
| Gurjun Dark - Gurjunene | "The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%)". Uses: Fragrance. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-003. Olfactive Profile: Balsamic, woody, sweet. EC No: 232-444-8. Origin: Malaysia. | New Jersey |
| Gurjunene 85%+ | "The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents". Uses: Fragrances, Cosmetics. Group: Plant Extracts. INCI Names: Gurjunene. Grades: INDUSTRIAL GRADE. CAS No. 489-40-7. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-005. Olfactive Profile: Balsamic, woody, sweet. EC No: 207-695-1. Origin: Malaysia. | New Jersey |
| Gurjun Light - Copaene | The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%). Uses: Fragrance Products. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-002. Olfactive Profile: Balsamic, woody, sweet, greasy, pepper. EC No: 232-444-8. Origin: Indonesia. | New Jersey |
| Gurjun Light - Gurjunene | The crude oil collected from gurjun tree (Popularly known as : Keruing Timber Tree or Kayu Lagan) is naturally dark in appearance, hence known as gurjun dark. The crude oil can also be re-distilled to obtain gurjun light Gurjun is primarily cultivated in the southeast asia region (Malay Peninsula, Sumatra, Borneo, The Philippines, Java, Bali, Lombok and Sumbawa). It is, however, important to note that the oils obtained from Gurjun trees in the above listed countries have different constituents The Indonesian variety of Gurjun oil has Alpha Copaene (Min 40%) as it's main component. The other quality from Malaysia/ Vietnam/ Cambodia is different as the main constituent is Gurjunene (Min 40%). Uses: Fragrance Products. Group: Plant Extracts. INCI Names: Dipterocarpus Oleoresin Balsam. Grades: INDUSTRIAL GRADE. CAS No. 8030-55-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: GB-004. Olfactive Profile: Balsamic, woody, earthy and warm. EC No: 232-444-8. Origin: Malaysia. | New Jersey |
| guselkumab | guselkumab is a selectively blocking agent for interleukin-23 (IL-23), a cytokine involved in plaque psoriasis. guselkumab was approved by FDA as an anti-inflammatory drug for the treatment of moderate to severe plaque psoriasis. Uses: Anti-inflammatory drug. Synonyms: Tremfya. CAS No. 1350289-85-8. Molecular formula: C6402H9864N1676O1994S42. Mole weight: 143.6. | |
| Guselkumab | Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with K d values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO 1959. CAS No. 1350289-85-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9931. | |
| Gusperimus | Gusperimus is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity. Gusperimus inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells; this agent may suppress growth of certain T-cell leukemia cell lines. Uses: Immunosuppressive agents. Synonyms: deoxyspergualin; Deoxyspergualin Hydrochloride; Gusperimus Trihydrochloride; BMS-181173; BMS181173; BMS 181173; BMY-42215-1; BMY 42215 1; NKT-01; NKT 01; NKT01. CAS No. 104317-84-2. Molecular formula: C17H37N7O3. Mole weight: 387.52. | |
| Gusperimus trihydrochloride | Gusperimus is a derivative of the anti-tumor antibiotic spergualin, which has immunosuppressive activity. Synonyms: Spanidin; NKT-01. Grades: 98%. CAS No. 85468-01-5. Molecular formula: C17H37N7O3.3HCl. Mole weight: 496.91. | |
| Gusperimus Trihydrochloride | Gusperimus Trihydrochloride is an immunosuppressive agent, which was effective both in preventing and treating graft-vs.-host disease in mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 85468-01-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H37N7O3; 3(HCl), Molecular Weight: 387.523364599999. US Biological Life Sciences. | Worldwide |
| Gut Microbial Metabolite Library | A unique collection of 352 gut microbial metabolites which can be used for HTS and HCS. Uses: Scientific use. Product Category: L2540. Categories: Gut Microbial Metabolite Libraries. |  |
| Guvacine hydrochloride | Guvacine hydrochloride is a specific GABA uptake inhibitor (IC50 = 14, 58, 119 and 1870 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1, respectively). Guvacine may be beneficial for the treatment of neuropsychiatric disorders. Synonyms: 1,2,5,6-Tetrahydropyridine-3-carboxylic acid hydrochloride. Grades: ≥99% by HPLC. CAS No. 6027-91-4. Molecular formula: C6H9NO2.HCl. Mole weight: 163.6. | |
| Guvacine hydrochloride | Guvacine hydrochloride is an alkaloid from the nut of Areca catechu , acts as an inhibitor of GABA transporter , and dispalys modest selectivity for cloned GABA transporters with IC 50 s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3). Uses: Scientific research. Group: Natural products. CAS No. 6027-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-100809. | |
| Guvacine Hydrochloride | A GABA uptake inhibitor. It is used for the treatment of neurodegenerative diseases. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Hydrochloride; 1,2,5,6-Tetrahydro-. Grades: Highly Purified. CAS No. 6027-91-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Guvacoline hydrobromide | Guvacoline hydrobromide. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-3-pyridinecarboxylic acid methyl ester hydrobromide. Grades: Highly Purified. CAS No. 17210-51-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C7H12BrNO2. US Biological Life Sciences. | Worldwide |
| Guvacoline, Hydrobromide (Norarecoline, Guvacine Methyl Ester, Hydrobromide) | A useful tool in the identification of muscarinic receptors. Group: Biochemicals. Alternative Names: Norarecoline, Guvacine Methyl Ester, Hydrobromide. Grades: Highly Purified. CAS No. 17210-51-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Guvacoline hydrochloride | Guvacoline hydrochloride, a pyridine alkaloid found in Areca triandra , can act as a weak full agonist of atrial and ileal muscarinic receptors [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6197-39-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5016. | |
| GV-196771 | GV-196771, an indole derivative, has been found to be a non-opioid analgesic agent which is also a NMDA antagonist binds to glycine-binding site and was once studied in pain therapy. Synonyms: GV-196771; GW-196771; GV 196771; GW 196771; GV196771; GW196771; AC1OC7O7; SCHEMBL499308; 4,6-dichloro-3-[(E)-(2-oxo-1-phenylpyrrolidin-3-ylidene)methyl]-1H-indole-2-carboxylic acid; GV196771A; GV 196771A; GV-196771A. Grades: 98%. CAS No. 166974-22-7. Molecular formula: C20H14Cl2N2O3. Mole weight: 401.24. | |
| GV-58 | GV-58, a pupin derivative, has been found to be a P/Q-type Ca²?-channel agonist that could be used to against neuromuscular weakness. IC50: 7.21/8.81 uM (N-type/P-Q-type Ca2+ channel). Uses: Gv-58 has been found to be a p/q-type ca²?-channel agonist that could be used to against neuromuscular weakness. Synonyms: GV-58; CS-3617; GV 58; CS 3617; GV58; CS3617; CHEMBL2206242; SCHEMBL17628602; BDBM50400564. Grades: 98%. CAS No. 1402821-41-3. Molecular formula: C18H26N6OS. Mole weight: 374.50. | |
| GVK-904 | GVK-904 is an inhibitor of Trk-A with high selectivity for wild-type cancers. GVK-904 is a non-ATP-competitive inhibitor. It can be used to treat cancers induced by Trk-A. Uses: Antitumor drug. Synonyms: GVK 904; GVK904. | |
| GW0742 | GW0742. Group: Biochemicals. Alternative Names: 4-[[[2-[3-Fluoro-4- (trifluoromethyl) phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy] acetic acid. Grades: Highly Purified. CAS No. 317318-84-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C21H17F4NO3S2. US Biological Life Sciences. | Worldwide |
| GW0742 | GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPAR&gamma. Synonyms: GW0742; GW-0742; GW 0742; GW0742X; GW-0742X; GW 0742X; GW610742; GW-610742; GW 610742. Grades: >98%. CAS No. 317318-84-6. Molecular formula: C21H17F4NO3S2. Mole weight: 471.49. | |
| GW0742 | GW0742 is a potent PPARβ and PPARδ agonist, with an IC 50 of 1 nM for human PPARδ in binding assay, and EC 50 s of 1 nM, 1.1 μM and 2 μM for human PPARδ , PPARα, and PPARγ, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW610742. CAS No. 317318-84-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13928. | |
| GW0742 (4-[[[2-[3-Fluoro-4- (trifluoromethyl) phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy] Acetic Acid) | A small molecule agonist of the human Peroxisome Proliferator-Activated Recept d (PPAR d). It shows an EC50 of 1.1 nM against PPAR d with 100-fold selectivity over the other human subtypes. Group: Biochemicals. Alternative Names: 4-[[[2-[3-Fluoro-4- (trifluoromethyl) phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy] Acetic Acid. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| GW 1100 | GW 1100 is a selective G protein-coupled receptor GPR40 antagonist. GW 1100 has been shown to reverse the effects GPR40 agonists which induce glucose-stimulated insulin secretion. Group: Biochemicals. Alternative Names: 4-[5-[ (2-Ethoxy-5-pyrimidinyl) methyl]-2-[[ (4-fluorophenyl) methyl]thio]-4-oxo-1 (4H) -pyrimidinyl]benzoic Acid Ethyl Ester; 1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone. Grades: Highly Purified. CAS No. 306974-70-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| GW-1100 | A cell-permeable pyrimidinylmethyl-pyrimidinone compound that acts as potent, reversible and non-competitive GPR40 antagonist. Shown to significantly reverse glucose-induced insulin secretion potentiated by GW9508 and only partially reduce linoleic acid effect in MIN6 cells. Synonyms: GW 1100; GW-1100; GW1100. Grades: >98%. CAS No. 306974-70-9. Molecular formula: C27H25FN4O4S. Mole weight: 520.58. | |
| GW 1100, GPR40 Antagonist (SB376752, 1-(4-Ethoxycarbonylphenyl)-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone) | A cell-permeable pyrimidinylmethyl-pyrimidinone compound that acts as potent, reversible and non-competitive GPR40 antagonist. Selectively blocks GPR40-mediated intracellular Ca2+ release stimulated by GPR40 Agonist GW9508 and linoleic acid (pIC50 of 5.99 in GPR40 expressing HEK293 cells) with no effect on GPR120-mediated activation. Shown to significantly reverse glucose-induced insulin secretion potentiated by GW9508 and only partially reduce linoleic acid effect in MIN6 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 306974-70-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GW1929 | Potent and subtype-selective (>1000-fold) PPARgamma agonist. Angiogenesis and apoptosis inhibitor. Anti-inflammatory. Anti-hyperglycemic and anti-hyperlipidemic agent. GW1929 is an antidiabetic; the glucose-lowering effect in rats is 100-fold more potent than that of troglitazone. Group: Biochemicals. Alternative Names: N-(2-Benzoylphenyl)-L-tyrosine PPARγ Agonist; (2S) - ( (2-Benzoylphenyl) amino-3- [4- [2- (methylpyridin-2-ylamino) ethoxy] phenyl] propionic acid. Grades: Highly Purified. CAS No. 196808-24-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C30H29N3O4. US Biological Life Sciences. | Worldwide |
| GW1929 | A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays). Synonyms: GW 1929; GW-1929. Grades: >98%. CAS No. 196808-24-9. Molecular formula: C30H29N3O4. Mole weight: 495.57. | |
| GW 1929 hydrochloride | GW 1929 hydrochloride is a selective and orally bioactive agonist of peroxisome proliferator-activated receptor (PPAR)γ (pEC50 = 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors, respectively). GW 1929 causes a decrease of glucose, fatty acid and triglyceride levels following oral administration in vivo. Synonyms: GW 1929 hydrochloride; GW1929 hydrochloride; GW-1929 hydrochloride; N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride; (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1217466-21-1. Molecular formula: C30H29N3O4.HCl. Mole weight: 532.03. | |
| GW2580 | GW2580 is an orally bioavailable inhibitor of cFMS kinase. GW2580 was found to completely inhibit human cFMS kinase in vitro at 0.06 microM and was inactive against 26 other kinases. GW2580 at 1 microM completely inhibited CSF-1-induced growth of mouse M-NFS-60 myeloid cells and human monocytes and completely inhibited bone degradation in cultures of human osteoclasts, rat calvaria, and rat fetal long bone. In contrast, GW2580 did not affect the growth of mouse NS0 lymphoblastoid cells, human endothelial cells, human fibroblasts, or five human tumor cell lines. GW2580 also did not affect lipopolysaccharide (LPS)-induced TNF, IL-6, and prostaglandin E2 production in freshly isolated human monocytes and mouse macrophages. After oral administration, GW2580 blocked the ability of exogenous CSF-1 to increase LPS-induced IL-6 production in mice, inhibited the growth of CSF-1-dependent M-NFS-60 tumor cells in the peritoneal cavity, and diminished the accumulation of macrophages in the peritoneal cavity after thioglycolate injection. Unexpectedly, GW2580 inhibited LPS-induced TNF production in mice, in contrast to effects on monocytes and macrophages in vitro. In conclusion, GW2580's selective inhibition of monocyte growth and bone degradation is consistent with cFMS kinase inhibition. The ability of GW2580 to chronically inhibit CSF-1 signaling through cFMS kinase in normal and tumor cells in vivo makes GW2580 a useful tool in assessing the role of cFMS kinase in normal and disease processes. Synonyms: GW 2580; GW-2580; GW2580. Grades: 0.98. CAS No. 870483-87-7. Molecular formula: C20H22N4O3. Mole weight: 366.421. | |
| GW 2580 | GW 2580. Group: Biochemicals. Alternative Names: 5-[[3-Methoxy-4-[ (4-methoxyphenyl) methoxy]phenyl]methyl]-2, 4-pyrimidinediamine. Grades: Highly Purified. CAS No. 870483-87-7. Pack Sizes: 10mg. Molecular Formula: C20H22N4O3, Molecular Weight: 366.41. US Biological Life Sciences. | Worldwide |
| GW274150 | GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) ( IC 50 =2.19 μM; K d =40 nM) and rat iNOS ( ED 50 =1.15 μM). GW274150 also displays less potency for both humans or rats endothelial NOS ( eNOS ) and neuronal NOS ( nNOS ). GW274150 exerts a protective role in an acute model of lung injury inflammation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 210354-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12119. | |
| GW 274150 | GW 274150 is a potent, long-acting and highly selective inhibitor of iNOS which have a very high degree of selectivity for iNOS versus both eNOS (>100-fold) and nNOS (>80-fold). GW 274150 shows analgesic effects in rat models of inflammatory and neuropath. Synonyms: (2S) -2-amino-4-[2- (1-aminoethylideneamino) ethylsulfanyl]butanoic acidGW-274150; GW 274150; GW274150. CAS No. 210354-22-6. Molecular formula: C8H17N3O2S. Mole weight: 219.30. | |
| GW274150 phosphate | GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) ( IC 50 =2.19 μM; K d =40 nM) and rat iNOS ( ED 50 =1.15 μM). GW274150 phosphate displays less potency for both humans or rats endothelial NOS ( eNOS ) and neuronal NOS ( nNOS ). GW274150 phosphate exerts a protective role in an acute model of lung injury inflammation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 438542-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12119A. | |
| GW284543 | GW284543 (UNC10225170) is a selective MEK5 inhibitor. It can reduce pERK5 and reduce endogenous MYC protein. Synonyms: CHEMBL531447; BCP31359; MFCD32067894; HY-114189. Grades: 98%. CAS No. 790186-68-4. Molecular formula: C23H20N2O3. Mole weight: 372.4. | |
| GW311616 | Potent, selective and orally active human neutrophil elastase (HNE) inhibitor (IC50 value 22 nM). GW311616A is selective over other human serine proteases (IC50 values >100 μM for trypsin, cathepsin G, and plasmin, >3 μM for chymotrypsin and tissue plasminogen activator), and does not inhibit AchE at 100 μM. Synonyms: GW-311616; GW 311616. Grades: >98%. CAS No. 198062-54-3. Molecular formula: C19H31N3O4S. Mole weight: 397.53. | |
| GW311616 hydrochloride | Potent, selective and orally active human neutrophil elastase (HNE) inhibitor (IC50 value 22 nM). GW311616A is selective over other human serine proteases (IC50 values >100 μM for trypsin, cathepsin G, and plasmin, >3 μM for chymotrypsin and tissue plasminogen activator), and does not inhibit AchE at 100 μM. Synonyms: GW-311616 hydrochloride; GW 311616 hydrochloride; GW311616A. Grades: >98%. CAS No. 197890-44-1. Molecular formula: C19H32ClN3O4S. Mole weight: 433.99. | |
| GW-3333 | GW-3333 is a dual inhibitors of tumor necrosis factor-alpha (TNF)-Converting Enzyme (TACE) and matrix metalloproteinases. Synonyms: GW-3333; GW3333; GW 3333; 3-[formyl(hydroxy)amino]-4-methyl-N-[3-methyl-1-oxo-1-(pyridin-2-ylamino)pentan-2-yl]-2-(2-methylpropyl)pentanamide. Grades: >98%. CAS No. 212609-68-2. Molecular formula: C22H36N4O4. Mole weight: 420.55. | |
| GW3965 | GW3965 is a potent, selective LXR agonist for hLXRα and hLXR&beta. When screened against a panel of nuclear receptors, it cross-reacted with only the pregnane X receptor (PXR). In Vitro: Recruit the steroid receptor coactivator 1 to human LXRα with EC50 of 125 nM in a cell-free ligand-sensing assay; Potent antagonistic activity against hLXRα and hLXRβ in cell-based assays with EC50 of 190 nM and 30 nM, respectively; In human islets, GW3965 (1 μM) reduces expression of selected pro-inflammatory cytokines including IL-8, monocyte chemotactic protein-1 and tissue factor In Vivo: At a dose of 10 mg/kg upregulates ABCA1 expression 8-fold and raises circulating levels of HDL by 30% with Cmax of 12.7 μg/mL and t1/2 of 2 hours. Uses: A liver x receptor agonist; represses the production of pro-inflammatory cytokines by murine mast cells; in vitro: reduces tissue factor production and inflammatory responses in human islets. Synonyms: GW3965; GW 3965; GW-3965; 2- (3- (3- ( (2-chloro-3- (trifluoromethyl) benzyl) (2, 2-diphenylethyl) amino) propoxy) phenyl) acetic acid hydrochloride. Grades: ≥ 98.0%. CAS No. 405911-09-3. Molecular formula: C33H31ClF3NO3. Mole weight: 582.05. | |
| GW3965 hydrochloride | GW3965 hydrochloride is a potent and selective liver X receptor (LXR) agonist with EC 50 s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 405911-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10627A. | |
| GW3965 Hydrochloride | GW3965 HCl is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively. Synonyms: GW3965 Hydrochloride; GW 3965 Hydrochloride; GW-3965 Hydrochloride. Grades: >98%. CAS No. 405911-17-3. Molecular formula: C33H31ClF3NO3.HCl. Mole weight: 618.51. | |
| GW-405833 | GW-405833 (L768242) is a potent, selective cannabinoid receptor 2 (CB 2 ) agonist with an EC 50 of 50.7 nM. GW-405833 also behaves as a noncompetitive CB 1 antagonist. GW-405833 suppresses inflammatory and neuropathic pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L768242. CAS No. 180002-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110036. | |
| GW405833 hydrochloride | GW-405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB 2 ) agonist with an EC 50 of 50.7 nM. GW-405833 hydrochloride also behaves as a noncompetitive CB 1 antagonist. GW-405833 hydrochloride suppresses inflammatory and neuropathic pain [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L768242 hydrochloride. CAS No. 1202865-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110036A. | |
| GW 406381 | GW 406381 is a selective cyclooxygenase-2 (COX-2) inhibitor that is effective in the treatment of inflammatory pain, neurodynia, Trauma and others. Uses: The treatment of inflammatory pain. Synonyms: GW-406381; GW 406381; GW406381. 2-(4-ethoxyphenyl)-3-(4-methylsulfonylphenyl)pyrazolo[1,5-b]pyridazine. Grades: 99%. CAS No. 221148-46-5. Molecular formula: C21H19N3O3S. Mole weight: 393.46. | |
| GW4064 | GW4064 is a selective non-steroidal agonist of farnesoid X receptor (FXR) with EC50 value of 15 nM. Synonyms: GW4064; GW-4064; GW 4064. Grades: >98%. CAS No. 278779-30-9. Molecular formula: C28H22Cl3NO4. Mole weight: 542.84. | |
| GW 4064 | GW 4064. Group: Biochemicals. Alternative Names: 3- [2- [2-Chloro-4- [ [3- (2, 6-dichlorophenyl) -5- (1-methylethyl) -4-isoxazolyl] methoxy] phenyl] ethenyl] -benzoic acid. Grades: Highly Purified. CAS No. 278779-30-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C28H22Cl3NO4. US Biological Life Sciences. | Worldwide |
| GW 441756 | GW 441756 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor (IC50 = 2 nM), reducing cell proliferation and potentiates the effects of chemotherapeutic agents. Uses: A specific tropomyosin-related kinase a (trka) inhibitor. Synonyms: GW-441756; GW 441756; GW441756. 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one;(3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one. Grades: ≥98%. CAS No. 504433-23-2. Molecular formula: C17H13N3O. Mole weight: 275.30. | |
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