A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| GRN-529 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| GroES mobile loop | GroES mobile loop is a highly flexible free GroES region that binds to GroES via residues at the tip of the loop. Synonyms: Glu-Thr-Lys-Ser-Ala-Gly-Gly-Ile-Val-Leu-Thr-Gly-Ser. Grade: ≥95%. Molecular formula: C51H90N14O20. Mole weight: 1219.36. |  |
| GRO-gamma human | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GRO? human | ?97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| GRO? human | recombinant, expressed in E. coli, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| GRO/KC (CXCL1) from rat | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| GRO/KC from mouse | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Gromwell Root Extract | Gromwell Root Extract. Applications: Anti-tumor effects,main role of the cardiovascular system, mainly used for hepatitis, dermatitis and baby, women vaginitis, cervicitis, and other drugs. Group: Others. Synonyms: Gromwell Root Extract; Lithospermum erythrorhizon. Purity: 30% Shikonin by UV. Appearance: Deep purple-red stiffen Cream. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Lithospermum erythrorhizon. Gromwell Root Extract; Lithospermum erythrorhizon; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-179. |  |
| Grossamide | Cis-Grossamide K is a natural alkaloid found in the herbs of Cannabis sativa L. Cis-Grossamide K exhibits a strong anti-melanogenic activity on the cells without high cell toxicity. Uses: Anti-melanogenic. Synonyms: 2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[3-[2-(4-hydroxyphenyl)et hylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydrobenzofuran-3-carboxamide. Grade: >97%. CAS No. 80510-06-1. Molecular formula: C36H36N2O8. Mole weight: 624.69. | |
| Grosvenorine | Grosvenorine is the major flavonoid compound of the fruits of Siraitia grosvenorii. Grosvenorine exhibits good antibacterial and antioxidant activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Momordica grosvenori lutein. Product Category: Inhibitors. Appearance: Powder. CAS No. 156980-60-8. Molecular formula: C33H40O19. Mole weight: 740.66. Purity: 0.98. IUPACName: 7-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one. Canonical SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C6=CC=C(C=C6)O)O)O)O. Density: 1.74±0.1 g/ml. Product ID: ACM156980608. Alfa Chemistry ISO 9001:2015 Certified. Categories: Grosvenor Cinema, Rayners Lane. |  |
| Grosvenorine | Grosvenorine. Group: Biochemicals. Grades: Plant Grade. CAS No. 156980-60-8. Pack Sizes: 10mg. Molecular Formula: C33H40O19, Molecular Weight: 740.66. US Biological Life Sciences. |  Worldwide |
| Ground Calcium Carbonate for Industry | Ground Calcium Carbonate for Industry. Grade: 95%. CAS No. 72608-12-9. Molecular formula: CaCO3||||CaCO3||||CaCO3||||CaCO3||||CCaO3. Mole weight: 100.09. | |
| Ground water | certified Reference Material. Group: Pharmacopeia & metrological institutes standards. | |
| Ground water (Br, high level) | certified Reference Material. Group: Certified reference materials (crms). | |
| Ground water (Br, low level) | certified Reference Material. Group: Certified reference materials (crms). | |
| Ground water (trace elements) | certified Reference Material. Group: Pharmacopeia & metrological institutes standards. | |
| Group III Caspase Inhibitor I | The Group III Caspase Inhibitor I controls the biological activity of Group III caspases (caspase-6, -8, -9, and -10). This small molecule/inhibitor is primarily used for Cancer applications. Group: Fluorescence/luminescence spectroscopy. | |
| Growth arrest-specific protein 7 (281-290) | Growth arrest-specific protein 7 (281-290) is a peptide derived from Growth arrest-specific protein 7. Growth arrest-specific protein 7 plays a role in promoting maturation and morphological differentiation of cerebellar neurons. Synonyms: GAS-7 (281-290). | |
| Growth Hormone, Human | Human growth hormone is a single-chain polypeptide hormone required for the growth of tissues. Synonyms: cb311; crecormon; humatrope; ly137998; norditropin; sj0011; OVINE SOMATOTROPIN; SOMATOTROPIN. Grade: 95%. CAS No. 12629-01-5. Molecular formula: C990H1529N263O299S7. Mole weight: 22124.12. | |
| GRP (14-27) (human, porcine, canine) | GRP (14-27) (human, porcine, canine). Synonyms: C-Terminal peptide bombesin; Gastrin releasing peptide (14-27); H-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2. CAS No. 81608-29-9. Molecular formula: C75H110N24O16S2. Mole weight: 1667.98. | |
| Grp94 Inhibitor-1 | Grp94 Inhibitor-1 is a potent and selective inhibitor of Grp94 (IC50 = 2 nM), and over 1000-fold selectivity to Grp94 against Hsp90α. Synonyms: [1,1'-Biphenyl]-3-carboxamide, 4-[(trans-4-hydroxycyclohexyl)amino]-4'-(1-methylethyl)-; 4-[(trans-4-Hydroxycyclohexyl)amino]-4'-isopropyl-3-biphenylcarboxamide; rel-4-(((1R,4R)-4-hydroxycyclohexyl)amino)-4'-isopropyl-[1,1'-biphenyl]-3-carboxamide. Grade: ≥98%. CAS No. 2234897-35-7. Molecular formula: C22H28N2O2. Mole weight: 352.47. | |
| Grp94 Inhibitor-1 | Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90?[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2234897-35-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112910. |  |
| GRPP (human) | GRPP (human) is a synthetic analogue of a cleavage product resulting from proglucagon processing in pancreatic α- and intestinal L-cells. Synonyms: Preproglucagon (21-50) (human); H-Arg-Ser-Leu-Gln-Asp-Thr-Glu-Glu-Lys-Ser-Arg-Ser-Phe-Ser-Ala-Ser-Gln-Ala-Asp-Pro-Leu-Ser-Asp-Pro-Asp-Gln-Met-Asn-Glu-Asp-OH; glicentin-related polypeptide (human); L-arginyl-L-seryl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-seryl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-alanyl-L-seryl-L-glutaminyl-L-alanyl-L-alpha-aspartyl-L-prolyl-L-leucyl-L-seryl-L-alpha-aspartyl-L-prolyl-L-alpha-aspartyl-L-glutaminyl-L-methionyl-L-asparagyl-L-alpha-glutamyl-L-aspartic acid. Grade: ≥95%. CAS No. 1132745-52-8. Molecular formula: C136H215N41O58S. Mole weight: 3384.47. | |
| GRP (porcine) | GRP (porcine) is a mammalian bombesin-like peptide neurotransmitter that acts as an agonist for the gastrin-releasing peptide receptor (GRPR). It was shown to activate GABAergic interneurons in the amygdala resulting in an increase in GABA release and fear suppression in mice in vivo. Synonyms: Gastrin Releasing Peptide porcine. CAS No. 74815-57-9. Molecular formula: C126H198N38O31S2. Mole weight: 2805.31. | |
| GRPSp | GRPSp was found in the mud crab Scylla paramamosain. It is active against Gram-positive A. viridans, M. Luteus, (MIC=6-25 μg/ml). Grade: >97% by HPLC. | |
| Grubbs Catalyst, 2nd gen | 100mg Pack Size. Group: Catalysts. Formula: C46H65Cl2N2PRu. CAS No. 246047-72-3. Prepack ID 60505776-100mg. Molecular Weight 848.97. See USA prepack pricing. |  |
| Grubbs catalyst 2nd generation | Grubbs catalyst 2nd generation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidine]Ruthenium(IV)dichloride. Product Category: Polymer/Macromolecule. Appearance: Powder. CAS No. 246047-72-3. Molecular formula: C46H65Cl2N2PRu. Mole weight: 848.97. Purity: 0.97. IUPACName: benzylidene-[1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichlororuthenium;tricyclohexylphosphane. Canonical SMILES: CC1=CC(=C(C(=C1)C)N2CCN(C2=[Ru](=CC3=CC=CC=C3)(Cl)Cl)C4=C(C=C(C=C4C)C)C)C.C1CCC(CC1)P(C2CCCCC2)C3CCCCC3. Product ID: ACM246047723-2. Alfa Chemistry ISO 9001:2015 Certified. | |
| Grubbs Catalyst, 2nd Generation | Grubbs Catalyst, 2nd Generation is a ruthenium-based olefin metathesis catalyst. Group: Biochemicals. Grades: Highly Purified. CAS No. 246047-72-3. Pack Sizes: 250mg, 500 mg. Molecular Formula: C46H65Cl2N2PRu. US Biological Life Sciences. | Worldwide |
| Grubbs catalyst I | Grubbs catalyst I. Group: Biochemicals. Alternative Names: Bis- (tri cyclohexylphosphino) -benzylide ne ruthenium dichloride. Grades: Highly Purified. CAS No. 172222-30-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C44H74Cl2P2Ru. US Biological Life Sciences. | Worldwide |
| Grubbs catalyst II | Grubbs catalyst II. Group: Biochemicals. Alternative Names: [1, 3-Bis- (2, 4, 6-tri methyl phenyl) -2-imidazolidinylide ne ] -dichloro- (phenyl methyl ene ) (tri cyclohexylphosphine) -ruthenium . Grades: Highly Purified. CAS No. 246047-72-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C46H65Cl2N2PRu. US Biological Life Sciences. | Worldwide |
| GS-0573 | GS 0573 is an antiviral compound that has been studied for potential treatment of Feline herpesvirus 1 (FHV-1). Uses: Designed for use in research and industrial production. Additional or Alternative Names: GS 0573; GS0573; GS-0573. Product Category: Others. Appearance: Solid powder. CAS No. 113852-41-8. Molecular formula: C8H13N6O4P. Mole weight: 288.2. Purity: >98%. IUPACName: ((2-(2,6-diamino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid. Canonical SMILES: O=P(O)(O)COCCN1C2=NC(N)=NC(N)=C2N=C1. Product ID: ACM113852418. Alfa Chemistry ISO 9001:2015 Certified. Categories: GS-5734. | |
| GS143 | GS143 is a selec-tive I?B? ubiquitination inhibitor with an IC50 of 5.2 ?M for SCF?TrCP1-mediated I?B? ubiquitylation. GS143 sup-presses NF-?B acti-va-tion and tran-scrip-tion of tar-get genes and does not inhibit proteasome activity. GS143 has anti-asthma effect[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 916232-21-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110261. | |
| GS 143 | GS 143 is a β-TrCP1 ligase inhibitor. GS 143 exhibits inhibitory effects on IκBα ubiquitination (IC50 = 5.2 μM), LPS-induced expression of inflammatory cytokines in human myelomonocytic cells, antigen-induced NFκB expression, inflammation and mucus production in airways of OVA-sensitized mice. Synonyms: GS-143; GS 143; GS143; 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid. Grade: ≥98% by HPLC. CAS No. 916232-21-8. Molecular formula: C28H19FN2O4. Mole weight: 466.46. | |
| GS-283 | GS-283, an isoquinolin derivative, has been found to be histamine receptor and muscarinic receptor blocker. Synonyms: GS 283; GS-283; GS283; 6,7-Isoquinolinediol, 3,4-dihydro-1-((4-methoxyphenyl)methyl)-; 7-hydroxy-1-[(4-methoxyphenyl)methyl]-3,4-dihydro-2H-isoquinolin-6-one. Grade: 98%. CAS No. 149440-36-8. Molecular formula: C17H17NO3. Mole weight: 283.33. | |
| GS 389 | GS 389 is a novel tetrahydroisoquinoline analog which significantly increased cGMP levels in the rat aorta and inhibited cGMP phosphodiesterase from the rabbit brain. Uses: A novel tetrahydroisoquinoline analog. Synonyms: GS 389; GS-389; GS389. 6,7-dimethoxy-1-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline. Grade: ≥98%. CAS No. 41498-37-7. Molecular formula: C19H23NO3. Mole weight: 313.39. | |
| GS39783 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GS39783 | GS39783 is a positive allosteric modulator (PAM) of GABA B R. Positive modulation of the GABA B R can be used for the research of Nicotine addiction [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39069-52-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103475. | |
| GS 39783 | GS 39783 is an allosteric positive modulator of GABAB receptors, decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines. Uses: Positive allosteric modulator of gabab receptor function. Synonyms: GS39783; GS-39783; GS 39783; N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine; 4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine. Grade: ≥98%. CAS No. 39069-52-8. Molecular formula: C15H23N5O2S. Mole weight: 337.44. | |
| GS 39783 | GS 39783. Group: Biochemicals. Alternative Names: N4,N6-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine; N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine. Grades: Highly Purified. CAS No. 39069-52-8. Pack Sizes: 10mg. Molecular Formula: C15H23N5O2S, Molecular Weight: 337.44. US Biological Life Sciences. | Worldwide |
| GS-441524 | GS-441524 is an analog nucleotide inhibitor against feline infectious peritonitis virus (FIPV). EC50 is 0.78?uM. GS-441524 is also a metabolite and intermediate of Remdesivir. Synonyms: 2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile; Remdesivir metabolite GS-441524; GS 441524; GS441524; (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile. Grade: 97%. CAS No. 1191237-69-0. Molecular formula: C12H13N5O4. Mole weight: 291.26. | |
| GS-441524 | GS-441524, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC 50 of 0.78 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1191237-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103586. | |
| GS-443902 | GS-443902 is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. Uses: Antiviral agents. Synonyms: GS-441524 triphosphate; Remdesivir metabolite; RDV-TP. Grade: 99.87%. CAS No. 1355149-45-9. Molecular formula: C12H16N5O13P3. Mole weight: 531.20. | |
| GS-443902 trisodium | GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1.1 ?M, 5 ?M for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium. CAS No. 1355050-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126303C. | |
| GS-443902 trisodium | GS-443902 trisodium is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. Synonyms: GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium. Grade: 99%. CAS No. 1355050-21-3. Molecular formula: C12H12N5Na4O13P3. Mole weight: 619.13. | |
| GS-444217 | GS-444217 is an orally available and ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with IC50 of 2.87 nM. Synonyms: ASK1-IN-1. CAS No. 1262041-49-5. Molecular formula: C23H21N7O. Mole weight: 411.46. | |
| GS 6201 | GS 6201 is a selective A2B antagonist. Synonyms: CVT6883; CVT 6883; CVT-6883; GS6201; GS-6201; GS 6201; 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione. CAS No. 752222-83-6. Molecular formula: C21H21F3N6O2. Mole weight: 446.43. | |
| GS 6201 | GS 6201. Group: Biochemicals. Grades: Purified. CAS No. 752222-83-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GS-621763 | GS-621763 is an orally bioavailable prodrug of GS-441524. The nucleoside metabolite of remdesivir, GS-441524 displays potent anti-SARS-CoV-2 efficacy, and is being evaluated in clinical as an oral antiviral therapeutic for COVID-19. Synonyms: GS-441524 prodrug. Grade: 98%. CAS No. 2647442-13-3. Molecular formula: C24H31N5O7. Mole weight: 501.53. | |
| GS-7340 fumarate | Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. Synonyms: GS-7340 fumarate; GS 7340 fumarate; GS7340 fumarate; (S)-isopropyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate fumarate; TAF; GS734; GS-734; GS 7340; Tenofovir alafenamide fumarate; trade name: Genvoya. Grade: >98%. CAS No. 379270-38-9. Molecular formula: C25H33N6O9P. Mole weight: 59 | |
| GS87 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GS-9219 | GS-9219 is a prodrug of the acyclic nucleoside phosphonate analogue 9-(2-phosphonylmethoxyethyl)guanine (PMEG) with potential antineoplastic activity. Formulated to selectively accumulate in lymphocytes, nucleotide analogue GS 9219 is converted to its active metabolite, PMEG diphosphate (PMEGpp), via enzymatic hydrolysis, deamination, and phosphorylation; subsequently, PMEGpp is incorporated into nascent DNA chains by DNA polymerases, which may result in the termination of DNA synthesis, S-phase cell cycle arrest, and the induction of apoptosis in susceptible lymphoma cell populations. Synonyms: GS 9219; GS9219. CAS No. 859209-74-8. Molecular formula: C21H35N8O6P. Mole weight: 526.53. | |
| GS 9620 | GS 9620 is a potent and oral agonist of TLR7. Uses: Antiviral agents. Synonyms: 4-amino-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one; GS-9620; GS9620; Vesatolimod. Grade: 99.90%. CAS No. 1228585-88-3. Molecular formula: C22H30N6O2. Mole weight: 410.51. | |
| GS9667 | GS9667 is a new selective, partial agonist of the A(1) adenosine receptor (AR). It may be an effective therapy for Type 2 diabetes and dyslipidemia via lowering of free fatty acids (FFA). It was developed by Gilead and was in clinic phase 1 trials without progress. Uses: Gs966 may be an effective therapy for type 2 diabetes and dyslipidemia via lowering of free fatty acids (ffa). Synonyms: GS-9667; GS 9667; CVT-3619; CVT 3619; CVT3619. Grade: 98%. CAS No. 618380-90-8. Molecular formula: C21H24FN5O4S. Mole weight: 461.51. | |
| GS-9667 | GS-9667 (CVT 3619), a novel N 6 -5'-substituted adenosine analog, is a selective, partial agonist of the A 1 adenosine receptor (A 1 AdoR). GS-9667 binds to adipocyte membranes with high (K H =14 nM) and low (K L =5.4 μM) affinities. GS-9667 reduces cyclic AMP content and release of nonesterified fatty acids from epididymal adipocytes with IC 50 values of 6 nM and 44 nM, respectively. GS-9667 inhibits lipolysis and has the potential for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT 3619. CAS No. 618380-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19842. | |
| GS967 | GS967, also known as GS-458967, is a highly selective late sodium channel current blocker. The selective inhibition of late INa with GS967 can exert antiarrhythmic effects by suppressing EAD- and DAD-mediated extrasystolic activity in PFs and PV and SVC sleeve preparations. Synonyms: GS967; GS-967; GS 967; GS458967; GS 458967; GS-458967. Grade: 95%. CAS No. 1262618-39-2. Molecular formula: C14H7F6N3O. Mole weight: 347.22. | |
| GS-9822 | GS-9822 is one of novel non-catalytic site integrase inhibitors (NCINIs), which is a potential class of antiretroviral (ARV) agents. GS-9822 exhibits a potent effect against the T174I mutant (EC50: 3.0 ± 0.9 nM) and IN polymorphic variants (fold shift: 0.4 to 1.3). Studies showed that it has excellent pharmacokinetic properties and metabolic stability. Uses: Antiretroviral (arv) agent. Synonyms: 2219362-41-9; GS-9822; (S)-2-(tert-Butoxy)-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-3-(1-(oxetan-3-yl)piperidin-4-yl)-1H-indazol-5-yl)benzo[d]thiazol-6-yl)acetic acid; SCHEMBL20030699; DA-63908; HY-122229; CS-0082907; (2S)-2-tert-butoxy-2-[7-(4-chlorophenyl)-5-methyl-2-[1-methyl-3-[1-(oxetan-3-yl)-4-piperidyl]indazol-5-yl]-1,3-benzothiazol-6-yl]acetic acid. CAS No. 2219362-41-9. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| GSA 10 | GSA 10 is a quinolinecarboxamide derivative that acts as a Smoothened/Smo receptor agonist (EC50 = 1.2 μM). GSA 10 can promote differentiation of multipotent mesenchymal progenitor cells into osteoblasts. Uses: Smoothened (smo) receptor agonist. Synonyms: GSA-10; propyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate. Grade: >98%. CAS No. 300833-95-8. Molecular formula: C26H30N2O5. Mole weight: 450.53. | |
| GSA 10 | GSA 10. Group: Biochemicals. Grades: Purified. CAS No. 300833-95-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GSA-10 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Gsa I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 70°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme about 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CCCAG↑C G↓GGTCG. Activity: 10000-20000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Geobacillus stearothermophilus Y. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1115RE. | |
| GS-CA-1 | GS-CA-1 is a novel HIV capsid inhibitor developed by Gilead, which is a promisingly long-acting antiretroviral (ARV) agent. The preclinical study showed that GS-CA-1 could inhibit HIV-1 replication in human peripheral blood mononuclear cells (PBMCs) (EC50 = 140 pM). Uses: Long-acting antiretroviral (arv) agent. Synonyms: GS CA 1. Grade: 99.94%. CAS No. 2189684-45-3. Molecular formula: C41H36ClF8N7O5S2. Mole weight: 958.34. | |
| g-Secretase Inhibitor XX ( (S, S) -2-[2- (3, 5-Difluorophenyl) acetylamino]-N- (5-methyl-6-oxo-6, 7-dihydro-5H-dibenzo[b, d]azepin-7-yl) propionamide, DBZ, Dibenzazepine) | A cell-permeable dibenzazepine (dbz) compound that acts as a potent y-secretase inhibitor and significantly lowers both brain and plasma AB40 levels by ~72% in Tg2576 mutant APP transgenic mouse model (100umol/kg, b.i.d). Induces a heterogeneous reorganization of the crypt structural-proliferative units in the intestinal tract and of the stem cell niche in the colon. Also potently inhibits Notch processing (IC50=1.7nM in SupT1 cells) and induces conversion of proliferative crypt cells to post-mitotic goblet cells in both the C57BL/6 and ApcMin mouse models (10umol/kg, i.p). CAS Number:209984-56-5. Group: Biochemicals. Grades: Highly Purified. CAS No. 209984-56-5. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| GSG2 (470-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| GSH-CdTe, | GSH-CdTe. Group: Quantum dots. |  |
| GSI-136 | GSI-136 is an amyloid precursor protein secretase inhibitor. Uses: Γ-secretase inhibitor. Synonyms: GSI-136; GSI 136; GSI136. (S)-5-chloro-N-(3-ethyl-1-hydroxypentan-2-yl)thiophene-2-sulfonamide. Grade: ≥98%. CAS No. 443989-01-3. Molecular formula: C11H18ClNO3S2. Mole weight: 311.83. | |
| GSI-953 | Begacestat (GSI-953) is a selective β-secretase inhibitor that selectively inhibits cleavage of APP over Notch. GSI-953 is used for treating diseases such as cancer in relation to prevention of intestinal secretory metaplasia. Group: Biochemicals. Alternative Names: 5-Chloro-N-[ (1S) -3, 3, 3-trifluoro-1- (hydroxymethyl) -2- (trifluoromethyl) propyl]-2-thiophenesulfonamide; Begacestat; GSI 953. Grades: Highly Purified. CAS No. 769169-27-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GSK046 | GSK046 (iBET-BD2) is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. GSK046 has immunomodulatory activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: iBET-BD2. CAS No. 2474876-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136571. | |
| GSK046 | GSK046 is a potent, selective and orally active inhibitor of BET with immunomodulatory activity. GSK046 reduces the recruitment of BET proteins to interferon (IFN) target genes following IFN-γ stimulation. Synonyms: iBET-BD2; GSK 046; GSK-046. CAS No. 2474876-09-8. Molecular formula: C23H27FN2O4. Mole weight: 414.47. | |
| GSK0660 | GSK0660 is a selective PPARδ antagonist. GSK0660 blocks the effect of TNFα on the expressions of cytokines involved in leukocyte recruitment, including CCL8, CCL17, and CXCL10, and it may block TNFα-induced retinal leukostasis. Synonyms: GSK0660; GSK-0660; GSK 0660. Grade: 96%. CAS No. 1014691-61-2. Molecular formula: C19H18N2O5S2. Mole weight: 418.48. | |
| GSK0660 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
Our database is helping our users find suppliers everyday.
