American Chemical Suppliers

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Product
GZD856 GZD856 is a potent and orally active inhibitor of PDGFRα/β with IC50s of 68.6 and 136.6 nM, respectively. It is also a Bcr-AblT315I inhibitor with IC50s of 19.9 and 15.4?nM for native Bcr-Abl and the T315I mutant. GZD856 has antitumor activity. Synonyms: GZD-856; 4-Methyl-N-{4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-3-(pyrazolo[1,5-a]pyrimidin-6-ylethynyl)benzamide; Benzamide, 4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-. Grade: ≥98%. CAS No. 1257628-64-0. Molecular formula: C29H27F3N6O. Mole weight: 532.56. BOC Sciences 8
GZD856 formic GZD856 formic is a potent and orally active inhibitor of PDGFRα/β with IC50s of 68.6 and 136.6 nM, respectively. It is also a Bcr-AblT315I inhibitor with IC50s of 19.9 and 15.4?nM for native Bcr-Abl and the T315I mutant. GZD856 formic has antitumor activity. Synonyms: Benzamide, 4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-, formic acid. Grade: ≥98%. Molecular formula: C30H29F3N6O3. Mole weight: 578.58. BOC Sciences 8

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