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| Product | Description | |
|---|---|---|
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride, a muscle relaxant and anticonvulsant agent with good blood-brain barrier permeability, is a potent, selective, orally active and non-competitive antagonist of kainate- and AMPA-activated currents with IC50s of 7.5 and 11 μM, respectively. It has no activity against N-methyl-D-aspartate (NMDA) or γ-aminobutyric acid responses. Synonyms: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine dihydrochloride; Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 2319722-40-0. Molecular formula: C17H17Cl2N3O2. Mole weight: 366.24. |  |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride is an orally active, highly selective and noncompetitive AMPA/kainate receptor antagonist with the IC 50 values of 7.5 and 11μM, respectively. GYKI 52466 dihydrochloride has good blood brain barrier permeability and anticonvulsant effect. GYKI 52466 dihydrochloride can be used in Parkinson's disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2319722-40-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103234A. |  |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 102771-26-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GYKI 52466 hydrochloride | solid. Group: Fluorescence/luminescence spectroscopy. |  |
| GYKI 52466 hydrochloride | GYKI 52466 hydrochloride, a muscle relaxant and anticonvulsant agent with good blood-brain barrier permeability, is a potent, selective, orally active and non-competitive antagonist of kainate- and AMPA-activated currents with IC50s of 7.5 and 11 μM, respectively. It has no activity against N-methyl-D-aspartate (NMDA) or γ-aminobutyric acid responses. Synonyms: 4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride; 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1). Grade: ≥95%. CAS No. 192065-56-8. Molecular formula: C17H16ClN3O2. Mole weight: 329.78. | |
| GYKI 52466 Hydrochloride (1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride, GYKI-52,466, GYK I52466) | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 10-20uM) over kainate (IC50 ~450uM) and nMDA (IC50 >> 50uM) receptors. Commonly used as neuroprotectant, anticonvulsant, and skeletal muscle relaxant. Biologically viable admitted orally or systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 102771-26-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GYKI 53655 | GYKI 53655 is a selective AMPA receptor antagonist with anticonvulsant activity. Synonyms: GYKI 53655; GYKI53655; GYKI-53655; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide. Grade: 99%. CAS No. 143692-18-6. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| GYKI-53655 hydrate | >99.0% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GYKI 53655 hydrochloride | GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid ( AMPA ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY300168 hydrochloride. CAS No. 143692-48-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103228. | |
| GYKI 53655 hydrochloride | GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist displaying anticonvulsant activity. It also acts as a blocker of GluK3 homomeric receptors (IC50 = 63 μM) and GluK2b(R)/GluK3 heteroreceptors (IC50 = 32 μM) at high concentrations. GYKI 53655 prolongs the survival time after MgCl2- induced global cerebral ischemia. Synonyms: GYKI53655 Hydrochloride; GYKI53655 HCl; GYKI53655; GYKI 53655; GYKI-53655. LY 300168 hydrochloride; LY300168 hydrochloride; LY-300168 hydrochloride; 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride; 5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride. Grade: ≥99% by HPLC. CAS No. 143692-48-2. Molecular formula: C19H20N4O3.HCl. Mole weight: 388.85. | |
| GYKI 53655 Hydrochloride | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 6 and 5uM for GluA1 and GluA4, respectively) over kainate receptors (IC50 = 63 and 32uM for GluK3 and GluK2b/GluK3 receptors. Used as neuroprotectant and anticonvulsant, and a valuable tool for the study of AMPA receptor-mediated processes in vivo. Group: Biochemicals. Alternative Names: LY 300168, GYKI-53655 Hydrochloride, AMPA Glutamate Receptor Antagonist, GYKI 53655 Hydrochloride, 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride. Grades: Highly Purified. CAS No. 143692-48-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GYKI 53784 | GYKI-53784, a dioxolbenzene derivative, has been found to be a AMPA receptor antagonist that could block excitotoxicity and decrease auditory nerve activity at some extent. Synonyms: GYKI-53784; GYKI53784; GYKI 53784; LY 303070; LY-303070; LY303070; 7H-1,3-Dioxolo(4,5-h)(2,3)benzodiazepine-7-carboxamide, 8,9-dihydro-5-(4-aminophenyl)-N,8-dimethyl-, (R)-; UNII-91N8O25H4L; AC1MIO7T. Grade: 98%. CAS No. 161832-71-9. Molecular formula: C19H20N4O3. Mole weight: 352.39. | |
| Gymnema Extract (Ratio) | Gymnema Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gymnema Extract (Ratio). Cat No: EXTW-070. |  |
| Gymnema Extract (Standard) | Gymnema (Gymnema sylvestre) is an herb native to the tropical forests of southern and central India and Sri Lanka. Applications: Gymnema extract is one of the major botanicals being administered for those suffering from diabetes, in boosting insulin levels and controlling healthy blood sugar levels. it has unique property to directly mask the tongue's ability to taste sweet foods, at the same time suppresses glucose absorption from the intestine. Group: Others. CAS No. 122168-40-5. Purity: 25.0% 75.0% Gymnemic acid HPLC. Mole weight: 806.445257 g/mol. Gymnema Extract (Standard); 122168-40-5; C43H66O14. Cat No: EXTW-004. | |
| Gymnemagenin | Gymnemagenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 22467-07-8. Pack Sizes: 10mg. Molecular Formula: C30H50O6, Molecular Weight: 506.72. US Biological Life Sciences. | Worldwide |
| Gymnema Sylvestre Extract | Gymnema Sylvestre Extract. Applications: Used for health care products, dietary supplements, reduce hypoglycemic activity. Group: Others. Synonyms: Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult. CAS No. 1399-64-0. Purity: 25%, 75% Gymnemic Acid By UV. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Gymnema sylvestre ?Retz.? Schult. Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-098. | |
| Gymnema Sylvestre Extract 75% | Gymnema Sylvestre Extract 75%. |  CA, FL & NJ |
| Gymnemic acid | Gymnemic acid Inhibitor. Uses: Scientific use. Product Category: TN1718. CAS No. 122168-40-5. |  |
| Gymnemic acid I | Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I decreases the apoptosis under the high glucose stress [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 122168-40-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2541. | |
| Gymnemic Acid I | Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I decreases the apoptosis under the high glucose stress. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 122168-40-5. Molecular formula: C43H66O14. Mole weight: 806.97. Purity: 0.98. IUPACName: (2S,3S,4S,5R,6R)-6-[[(3S,4R,4aR,6aR,6bS,8S,8aR,9R,10R,12aS,14aR,14bR)-8a-(acetyloxymethyl)-8,9-dihydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid. Canonical SMILES: CC=C(C)C(=O)OC1C(C2(C(CC1(C)C)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)OC6C(C(C(C(O6)C(=O)O)O)O)O)C)COC(=O)C)O. Product ID: ACM122168405. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Gymnemic Acid I | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 122168-40-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Gymnestrogenin | Gymnestrogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19942-02-0. Pack Sizes: 5mg. Molecular Formula: C30H50O5, Molecular Weight: 490.73. US Biological Life Sciences. | Worldwide |
| Gymnin | Gymnin is a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill). Gymnin exerts antifungal activity against F.oxysporum and M.arachidicola, with an IC50 of 2 μM for the former fungus and 10 μM, respectively. It inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase. | |
| Gynostemma Extract | Gynostemma Extract (Ginsenoside C-Mx1) is a natural product. Uses: Scientific research. Group: Natural products. Alternative Names: Ginsenoside C-Mx1; Gypenoside IX. CAS No. 80321-63-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0167. | |
| Gynostemma Extract | Gynostemma extract is prepared from the leaf of Gynostemma, a cucurbitaceous plant belongs to perennial grass nature lianas grows in the southeastern regions of China. Gynostemma pentaphyllum extract contains more than 80 different saponins, so is also known as southern ginseng. Gynostemma extract gypenoside is widely used as an anti aging supplement, or a tonic to treat bronchitis, strengthen the body, reduce fatigue, and reinforce overall health. Group: Others. Gynostemma Extract; Gynostemma Pentaphyllum Thunb. Cat No: EXTC-023. | |
| gynostemma pentaphylla extractive | Anti-cancer: on liver cancer, lung cancer, metrocarcinoma, melanotic sarcoma; Anti-aging and improving immunity; Reducing blood fat; Prevent side-effect of glucocorticoid. Uses: Designed for use in research and industrial production. Product Category: Material of health food. Appearance: light yellow grown powder. CAS No. 15588-68-8. Molecular formula: C80H126O44. Mole weight: 1791.83. Product ID: ACM15588688. Alfa Chemistry ISO 9001:2015 Certified. | |
| Gynostemma Pentaphyllum Extract (Ratio) | Gynostemma Pentaphyllum Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gynostemma Pentaphyllum Extract (Ratio). Cat No: EXTW-037. | |
| Gypenoside I | Gypenoside I is an intricate phytochemical abundantly occurring in the plant known as Gynostemma Pentaphyllum. The multifaceted potential of Gypenoside I resides in its astonishingly promising capacity to potentially study a diverse array of maladies, which encompass the realms of cancer, diabetes, inflammation, as well as cardiovascular disorders. Synonyms: (3β,12β)-20-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→6)-O-[β-D-glucopyranosyl-(1→2)]-β-D-glucopyranoside. CAS No. 85889-20-9. Molecular formula: C60H102O27. Mole weight: 1255.44. | |
| Gypenoside XLIX | Gypenoside XLIX. Group: Biochemicals. Grades: Plant Grade. CAS No. 94987-08-3. Pack Sizes: 20mg. Molecular Formula: C52H86O21, Molecular Weight: 1047.23. US Biological Life Sciences. | Worldwide |
| Gypenoside XLVI | Gypenoside XLVI. Group: Biochemicals. Grades: Plant Grade. CAS No. 94705-70-1. Pack Sizes: 10mg. Molecular Formula: C48H82O19, Molecular Weight: 963.16. US Biological Life Sciences. | Worldwide |
| Gypenoside XVII | Gypenoside XVII. Group: Biochemicals. Alternative Names: Gynosaponin S. Grades: Plant Grade. CAS No. 80321-69-3. Pack Sizes: 20mg. Molecular Formula: C48H82O18, Molecular Weight: 947.154. US Biological Life Sciences. | Worldwide |
| GYPGQV trifluoroacetate salt | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Gypsetin | It is produced by the strain of Nannizzia gypsea var. incurvata IFO 9228. It can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with IC50 of 18 μmol/L, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μmol/L. It also inhibits [14C] oleic acid from forming cholesterol esters with IC50 of 0.65 μmol/L. Synonyms: Gypsetine; (-)-Gypsetin; 8a,16a-Dihydroxy-5a,13a-bis(1,1-dimethylallyl)-(1)-benzazolidine-(3''',2''':4'',5'')azolidino-(1'',2'':4',5')(1,4)perhydrodiazin-(1',2':1,5)azolidino-(2,3-b)-(1)-benzazolidine-7,15-dione; Pyrazino(1'',2'':1,5; 4'',5'':1',5')dipyrrolo(2,3-b:2',3'-b')diindole-7,15(5H,7aH)-dione,5a,13a-bis(1,1-dimethyl-2-propenyl)-5a,8,8a,13,13a,15a,16,16a-octahydro-8a,16a-dihydroxy-, (5aalpha,7aalpha,8abeta,13abeta,15aalpha,16aalpha)-. CAS No. 155114-38-8. Molecular formula: C32H36N4O4. Mole weight: 540.66. | |
| Gypsogenic acid | Gypsogenic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 5143-5-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Gypsogenin 3-O- β-D-glucuronopyranoside | Gypsogenin 3-O- β-D-glucuronopyranoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 96553-02-5. Pack Sizes: 10mg. Molecular Formula: C36H54O10, Molecular Weight: 646.82. US Biological Life Sciences. | Worldwide |
| Gypsum | Gypsum. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS001853. Shipping: Room Temperature. | |
| Gypsum byproduct | Gypsum byproduct. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS001854. Shipping: Room Temperature. | |
| Gypsum (NIM-GBW03111) | Gypsum (NIM-GBW03111). Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS008571. Shipping: Room Temperature. | |
| Gypsum Submicron | Gypsum Submicron. Group: Mineral trioxide aggregate (mta). Mole weight: CaSO4 2H2O. 99.9%. |  |
| Gyramide A hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Gyrane | Gyrane. CAS No. 24237-00-1. VIGON Item # 503223. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Gyrophoric acid | Gyrophoric acid isolated from the herbs of Parmelia tinctorum Despr. Uses: Anti-tumor; anti-cancer; antibacterial; antimicrobial; anti-proliferative/cytotoxic effect. Synonyms: triorsellinic acid; 4-[4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoic acid. Grade: 0.98. CAS No. 548-89-0. Molecular formula: C24H20O10. Mole weight: 468.4. | |
| GYY4137 | GY4137 is a sustained-release H2S donor possessing vasodilatory, antihypertensive, and anti-inflammatory activities. GY4137 can inhibit cell growth, induce apoptosis, and cause cell cycle arrest by blocking the STAT3 pathway, demonstrating potent anticancer activity[1][2][3][4][5][6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106740-09-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107632. | |
| GYY 4137 | Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism. Group: Biochemicals. Grades: Highly Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H16NO2PS2 C4H9NO. US Biological Life Sciences. | Worldwide |
| GYY4137 Dichloromethane complex | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GYY 4137 morpholine salt | GYY 4137 morpholine salt. Group: Biochemicals. Grades: Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYY-4137 Morpholine salt | GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Synonyms: GYY4137; GYY-4137; GYY 4137; GYY 4137 morpholine salt; ZYJ1122; ZYJ 1122; ZYJ-1122. GYY4137 Morpholine salt; (4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine; ZYJ1122 morpholine salt; ZYJ-1122 morpholine salt. Grade: ≥95%. CAS No. 106740-09-4. Molecular formula: C15H25N2O3PS2. Mole weight: 376.47. | |
| GZ-793A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GZD824 | GZD824 potently suppressed proliferation of Bcr-Abl-positive K562 and Ku812 human CML cells with IC(50) values of 0.2 and 0.13 nM, respectively. It also displayed good oral bioavailability (48.7%), a reasonable half-life (10.6 h), and promising in vivo antitumor efficacy. GZD824 induced tumor regression in mouse xenograft tumor models driven by Bcr-Abl(WT) or the mutants and significantly improved the survival of mice bearing an allograft leukemia model with Ba/F3 cells harboring Bcr-Abl(T315I). Synonyms: GZD824; GZD 824; GZD-824. Grade: >98%. CAS No. 1257628-77-5. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| GZD824 Dimesylate | GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively. Synonyms: Olverembatinib dimesylate; HQP1351 dimesylate; GZD 824 Dimesylate; GZD-824 Dimesylate; 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide dimethanesulfonate; Benzamide, 4-methyl-N-(4-((4-methyl-1-piperazinyl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(1H-pyrazolo(3,4-b)pyridin-5-yl)ethynyl)-, methanesulfonate (1:2). Grade: ≥99%. CAS No. 1421783-64-3. Molecular formula: C29H27F3N6O.2CH4O3S. Mole weight: 724.77. | |
| GZD856 | GZD856 is a potent and orally active inhibitor of PDGFRα/β with IC50s of 68.6 and 136.6 nM, respectively. It is also a Bcr-AblT315I inhibitor with IC50s of 19.9 and 15.4?nM for native Bcr-Abl and the T315I mutant. GZD856 has antitumor activity. Synonyms: GZD-856; 4-Methyl-N-{4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-3-(pyrazolo[1,5-a]pyrimidin-6-ylethynyl)benzamide; Benzamide, 4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-. Grade: ≥98%. CAS No. 1257628-64-0. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| GZD856 formic | GZD856 formic is a potent and orally active inhibitor of PDGFRα/β with IC50s of 68.6 and 136.6 nM, respectively. It is also a Bcr-AblT315I inhibitor with IC50s of 19.9 and 15.4?nM for native Bcr-Abl and the T315I mutant. GZD856 formic has antitumor activity. Synonyms: Benzamide, 4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)-, formic acid. Grade: ≥98%. Molecular formula: C30H29F3N6O3. Mole weight: 578.58. | |
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