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| Product | Description | |
|---|---|---|
| HCN4 Control Peptide (Hyperpolarization-activated Cyclic Nucleotide-gated Potassium Channel 4) | HCN4 Control Peptide (Hyperpolarization-activated Cyclic Nucleotide-gated Potassium Channel 4). Group: Molecular Biology. Pack Sizes: 120ug. US Biological Life Sciences. |  Worldwide |
| HCoV-229E-IN-1 | HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC 50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2639757-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132169. |  |
| HCoV-OC43-IN-1 | HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC 50 : 90 nM). HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2809363-81-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156346. | |
| HCPI | HCPI. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[4-(Hydrazinocarbonyl)phenyl]-4,5-diphenylimidazole. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 151589-38-7. Molecular formula: C22H18N4O. Mole weight: 354.4. Purity: 90%+. IUPACName: 4-(4,5-diphenyl-1H-imidazol-2-yl)benzohydrazide. Canonical SMILES: C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C(=O)NN)C4=CC=CC=C4. Product ID: ACM151589387-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: H. C. Pitney Variety Store Building. |  |
| HCT-116 Transfection Reagent | Transfection Reagent for HCT116 Colon Carcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6812. |  Nevada, Texas, USA |
| hCT (Calcitonin), Human | It is a cell-penetrating peptide (CPP) derived from the human calcitotnin protein sequence. It has good proteolytic resistance and can permeate cell membrane without significant influence at low micromolar concentration. hCT can be conjugated with large molecules and used as a drug delivery vehicle. Synonyms: H-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-OH. Grades: >98%. Molecular formula: C121H176N30O35. Mole weight: 2610.91. |  |
| HC Toxin | HC Toxin is a cell-permeable histone deacetylase (HDAC) inhibitor (IC50 = 30 nM) that inhibits HDACs in maize, Physarum and chicken. HC Toxin is metabolized from H. carbonum (now C. carbonum), and displays antifungal and antiproliferative effects. Synonyms: Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine); Cyclo(aoe-pro-ala-ala). Grades: ≥95%. CAS No. 83209-65-8. Molecular formula: C21H32N4O6. Mole weight: 436.50. | |
| HC-Toxin | HC-Toxin, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC 50 of 30 nM [1]. HC-Toxin induces tumor cell apoptosis and has anticancer effects [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83209-65-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-126856. | |
| HC toxin from Helminthosporium carbonum | lyophilized powder. Group: Fluorescence/luminescence spectroscopy. |  |
| HCTU | HCTU is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W010951. | |
| HCTU | Aminium-based coupling reagent, analogous to HBTU, which in comparative studies was found to give superior results to TBTU in the synthesis of difficult peptides, in hindered couplings, and cyclizations. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. |  Luxembourg Bio Technologies |
| HCTU | HCTU. Group: Biochemicals. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N,N,N',N'-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium hexafluorophosphate; 1-[Bis (dimethylamino) methylen]-5-chlorobenzotriazolium 3-oxide hexafluorophosphate. Grades: Highly Purified. CAS No. 330645-87-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C11H15ClF6N5OP. US Biological Life Sciences. | Worldwide |
| HCV371 | HCV371 is a potent and selective HCV NS5B polymerase inhibitor. It binds the NS5B with an apparent dissociation constant of 150 nM, which leads to high selectivity and lack of cytotoxicity in the antiviral assays. It displayed broad inhibitory activities against the NS5B RdRp enzyme. It showed no inhibitory activity against a panel of human polymerases, including mitochondrial DNA polymerase gamma and other unrelated viral polymerases. Synonyms: HCV-371; HCV 371; HCV371. (R)-2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid. Grades: 98%. CAS No. 675184-27-7. Molecular formula: C18H20N2O3. Mole weight: 312.37. | |
| HCV-IN-4 | HCV-IN-4 is a potent and orally bioactive HCV NS5A inhibitor, displaying great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s values of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively. Synonyms: HCV-IN-4|CHEMBL3980210|HY-P0162|CS-0020242. Grades: ≥98% (HPLC). CAS No. 2058080-25-2. Molecular formula: C52H58FN9O8. Mole weight: 956.07. | |
| H-Cys-4-abz-met-oh | H-Cys-4-abz-met-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-CYS-4-ABZ-MET-OH;FTASE INHIBITOR II;CYSTEINE-(4-AMINOBENOZYL)METHIONINE. Product Category: Heterocyclic Organic Compound. CAS No. 156707-43-6. Molecular formula: C15H21N3O4S2. Mole weight: 371.47. Product ID: ACM156707436. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Cys(4-methoxytrityl)-2-chlorotrityl resin | Synonyms: H-Cys(Mmt)-2-ClTrt resin. | |
| H-Cys(Acm)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: S-acetamidomethyl-L-cysteine-2-chlorotrityl resin. Pack Sizes: 5g, 25g. |  |
| H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH | Synonyms: H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH. CAS No. 166184-23-2. Molecular formula: C41H61N13O15S2. Mole weight: 1040.15. | |
| H-Cys(bzl)-gly-oh | H-Cys(bzl)-gly-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-CYS(BZL)-GLY-OH;S-BENZYL-L-CYSTEINYL-GLYCINE. Product Category: Heterocyclic Organic Compound. CAS No. 7669-84-3. Molecular formula: C12H16N2O3S. Mole weight: 268.33. Product ID: ACM7669843. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Cys(bzl)-obzl.hcl | H-Cys(bzl)-obzl.hcl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-Cys(Bzl)-OBzl.HCl. Product Category: Heterocyclic Organic Compound. CAS No. 4561-11-9. Molecular formula: C17H20ClNO2S. Mole weight: 337.86. Purity: 0.96. IUPACName: benzyl (2R)-2-amino-3-benzylsulfanylpropanoate;hydrochloride. Canonical SMILES: C1=CC=C(C=C1)COC(=O)C(CSCC2=CC=CC=C2)N.Cl. Product ID: ACM4561119. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Cys(Npys)-D-Ala-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2 | Synonyms: Cys(Npys)-Ala-(D-Arg)9; D-Argininamide, 3-[(3-nitro-2-pyridinyl)dithio]-L-alanyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-; 3-[(3-Nitro-2-pyridinyl)dithio]-L-alanyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide. Grades: ≥95%. CAS No. 1676104-79-2. Molecular formula: C65H123N41O13S2. Mole weight: 1751.07. | |
| H-Cys-ser-cys-lys-asp-met-thr-asp-lys-glu-cys-leu-asn-phe-cys-his-gln-asp-val-ile-trp-oh | H-Cys-ser-cys-lys-asp-met-thr-asp-lys-glu-cys-leu-asn-phe-cys-his-gln-asp-val-ile-trp-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SARAFOTOXIN A;SARAFOTOXIN A (ATRACTASPIS ENGADDENSIS);SARAFOTOXIN S6A;SARAFOTOXIN S6A1;SARAFOTOXIN S6A (ATRACTASPIS ENGADDENSIS);H-CYS-SER-CYS-LYS-ASP-MET-THR-ASP-LYS-GLU-CYS-LEU-ASN-PHE-CYS-HIS-GLN-ASP-VAL-ILE-TRP-OH;CYS-SER-CYS-LYS-ASP-MET-THR-ASP-LYS-. Product Category: Heterocyclic Organic Compound. CAS No. 126738-34-9. Molecular formula: C105H156N28O34S5. Mole weight: 2514.85. Purity: 0.96. IUPACName: Sarafotoxin S6a. Product ID: ACM126738349. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Cysteamine-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: 2-Aminoethanethiol-2-chlorotrityl resin. Pack Sizes: 5g, 25g. | |
| H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (Disulfide bond) | It is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: CTTHWGFTLC, CYCLIC; L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide; MMP-2/MMP-9 Inhibitor III; Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor III. Grades: ≥90%. CAS No. 244082-19-7. Molecular formula: C52H71N13O14S2. Mole weight: 1166.33. | |
| H-Cys(Trt)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: S-Trityl-L-cysteine-2-chlorotrityl resin. Pack Sizes: 5g, 25g. | |
| H-D-2-Nal-OH HCl | Synonyms: 3-(2-Naphthyl)-D-alanine hydrochloride; (R)-2-Amino-3-(naphthalen-2-yl)propanoic acid hydrochloride. Grades: 95%. CAS No. 122745-11-3. Molecular formula: C13H13NO2·HCl. Mole weight: 251.8. | |
| H-D-3-Pal-OH 2HCl | H-D-3-Pal-OH 2HCl, a synthetic peptide of scientific interest, has the potential to be a promising avenue in the pursuit of new treatments for diseases of varying kinds. Research into the properties of this compound suggests its ability to inhibit cell proliferation and promote apoptosis in oncogenic cells. Interestingly, it may also function as an immunomodulator and possess therapeutic applications towards autoimmune disorders. These findings speak to the complex and multifaceted nature of H-D-3-Pal-OH 2HCl and the implications it could have in furthering scientific understanding of these conditions. Synonyms: (R)-2-Amino-3-(pyridin-3-yl)propanoic acid dihydrochloride; H-D-3-Pal-OH.2HCl; 3-(3-Pyridyl)-D-alanine dihydrochloride. Grades: 95%. CAS No. 93960-21-5. Molecular formula: C8H12Cl2N2O2. Mole weight: 239.10. | |
| H-D-Abu-OtBu | Synonyms: (R)-tert-Butyl 2-Aminobutanoate; (2R)-2-aminobutyric acid tert-butyl ester; D-2-Aminobutyric acid tert-butyl ester; 2-Methyl-2-propanyl (2R)-2-aminobutanoate; Butanoic acid, 2-amino-, 1,1-dimethylethyl ester, (2R)-; D-α-Aminobutyric acid t-butyl ester. Grades: 95%. CAS No. 313994-32-0. Molecular formula: C8H17NO2. Mole weight: 159.23. | |
| HDAC10 FLAG tag active human | recombinant, expressed in baculovirus infected Sf9 cells, ?38% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-10 human | recombinant, expressed in baculovirus infected insect cells, ?10% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-11 human | recombinant, expressed in baculovirus infected insect cells, ?10% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC 1 from Plasmodium falciparum | recombinant, expressed in baculovirus infected insect cells, ?40% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-1 human | recombinant, expressed in baculovirus infected insect cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC2, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC2 FLAG tag human | recombinant, expressed in baculovirus infected insect cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC 2 His tag human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC2-IN-2 | HDAC2-IN-2 (compound 124) is an inhibitor of HDAC2 with Kd value of 0.1-1 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 332169-78-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164050. | |
| HDAC3 human | recombinant, expressed in insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC3 Inhibitor | HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM, IC50s = 0.95 nM). HDAC3 inhibitors increase histone acetylation and restore normal transcriptional patterns. Treatment with inhibitors primarily targeting HDAC3, including some with additional activity on HDAC1, led to improvement in motor function and working memory in N-terminal transgenic HD mice. Synonyms: Histone Deacetylase 3 Inhibitor; (E) -3-Phenyl-N-[[4- (propylaminocarbamoyl) phenyl]methyl]prop-2-enamide. Grades: ≥98%. CAS No. 2044701-99-5. Molecular formula: C20H23N3O2. Mole weight: 337.4. | |
| HDAC-3/NCOR2 human | recombinant, expressed in baculovirus infected insect cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-4 human | recombinant, expressed in baculovirus infected insect cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC5, active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-5 full length human | recombinant, expressed in baculovirus infected insect cells, ?10% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-5 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6 FLAG tag active human | recombinant, expressed in baculovirus infected Sf9 cells, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6 H216A human | recombinant, expressed in baculovirus infected Sf9 cells, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6 H611A human | recombinant, expressed in baculovirus infected Sf9 cells, ?79% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-6 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6-IN-23 | HDAC6-IN-23 (compound 9) is an orally active HDAC6 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2991427-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156274. | |
| HDAC6-IN-26 | HDAC6-IN-26 (compound 23) is a potent inhibitor of HDAC6 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2991427-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157219. | |
| HDAC7, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-7 human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-8 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC9, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-9 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Class 2a Substrate 2, fluorogenic | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Class 2a Substrate, fluorogenic | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-IN-1 | HDAC-IN-1, an analogue of MC 1568, is a Iia HDACs inhibitor that could probably influence myogenesis and adipogenesis. Uses: Hdac-in-1 is a iia hdacs inhibitor that could probably influence myogenesis and adipogenesis. Synonyms: MC1568; MC 1568; MC-1568; HDAC-IN-1; HDAC IN 1. Grades: 98%. CAS No. 1239610-44-6. Molecular formula: C17H15FN2O3. Mole weight: 314.31. | |
| HDAC-IN-2 | HDAC-IN-2, a selective HDAC inhibitor, has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.It is under Phase II trials against Multiple myeloma. IC50: 4 nM and 76 nM for. Uses: Hdac-in-2 is a selective hdac inhibitor that has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.it is under phase ii trials against multiple myeloma. Synonyms: ACY-241; ACY 241; ACY241; HDAC-IN-2; Citarinostat; 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide; UNII-441P620G3P; 441P620G3P; Citarinostat. Grades: 98%. CAS No. 1316215-12-9. Molecular formula: C24H26ClN5O3. Mole weight: 467.95. | |
| HDAC-IN-4 | HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1252003-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128763. | |
| HDAC-IN-55 | HDAC-IN-55(8j) is a small molecular compound that can increase the expression of E-cadherin and inhibit the proliferation of cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268674-16-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-153607. | |
| HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3 | The HDAC Inhibitor XIX, Compound 2, also referenced under CAS 6953-61-3, controls the biological activity of HDAC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Inhibitor XVII ((E)-N-Hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamide, Histone Deacetylase Inhibitor XVII) | A cell-permeable N-hydroxycinnamide derivative that acts a highly potent and HDAC8-selective histone deacetylase inhibitor (IC50 = 27nM), displaying much reduced or little potency against HDAC1/3 (IC50 = 3.0uM), HDAC2/4/6/10/11 (IC50 >20uM), or total HDAC activity in HeLa nuclear extract (IC50 >10uM). Reported to preferentially inhibit the proliferation of human lung cancer cells CL1-5, H1299, and A549 (IC50 from 7 to 8uM), while being much less toxic to normal human lung IMR-90 cells (73% inhibition at 40uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??NO?, Primary Target IC50: 27nM. US Biological Life Sciences. | Worldwide |
| HDAC Inhibitor XXIII, Tubastatin A | The HDAC Inhibitor XXIII, Tubastatin A controls the biological activity of HDAC. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Inhibitor XXIII, Tubastatin A (N-Hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-ylmethyl)benzamide, HCl) | A cell-permeable carbazolohydroxamate compound that acts as a highly potent, reversible and active-site zinc-binding HDAC6 inhibitor with excellent selectivity among other HDAC isozymes (IC50=0.015, 0.854, 16.4uM for HDAC6, HDAC8 and HDAC1, respectively) with no activity towards HDAC2, 3, 4, 7, 9, 10 and 11 (IC50>30uM). Shown to induce a-tubulin hyperacetylation at 2.5uM, and offer complete neuroprotection in primary cortical rat neuronal cells against homocysteic acid (HCA)-induced oxidative stress at 10uM with no noticeable neurotoxicity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| HDAC Inhibitor XXII, NCH51 - CAS 848354-66-5 | The HDAC Inhibitor XXII, NCH51, also referenced under CAS 848354-66-5, controls the biological activity of HDAC. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Substrate 1, fluorogenic | ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Substrate 2, fluorogenic | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Substrate 3, fluorogenic | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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