A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC 50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2639757-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132169.
HCoV-OC43-IN-1
HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC 50 : 90 nM). HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2809363-81-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156346.
HCT-116 Transfection Reagent
Transfection Reagent for HCT116 Colon Carcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6812.
Nevada, Texas, USA
hCT (Calcitonin), Human
It is a cell-penetrating peptide (CPP) derived from the human calcitotnin protein sequence. It has good proteolytic resistance and can permeate cell membrane without significant influence at low micromolar concentration. hCT can be conjugated with large molecules and used as a drug delivery vehicle. Synonyms: H-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-OH. Grades: >98%. Molecular formula: C121H176N30O35. Mole weight: 2610.91.
HC Toxin
HC Toxin is a cell-permeable histone deacetylase (HDAC) inhibitor (IC50 = 30 nM) that inhibits HDACs in maize, Physarum and chicken. HC Toxin is metabolized from H. carbonum (now C. carbonum), and displays antifungal and antiproliferative effects. Synonyms: Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine); Cyclo(aoe-pro-ala-ala). Grades: ≥95%. CAS No. 83209-65-8. Molecular formula: C21H32N4O6. Mole weight: 436.50.
HC-Toxin
HC-Toxin, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC 50 of 30 nM [1]. HC-Toxin induces tumor cell apoptosis and has anticancer effects [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83209-65-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-126856.
HCTU
HCTU is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W010951.
HCTU
Aminium-based coupling reagent, analogous to HBTU, which in comparative studies was found to give superior results to TBTU in the synthesis of difficult peptides, in hindered couplings, and cyclizations. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9.
Luxembourg Bio Technologies
HCTU
HCTU. Group: Biochemicals. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N,N,N',N'-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium hexafluorophosphate; 1-[Bis (dimethylamino) methylen]-5-chlorobenzotriazolium 3-oxide hexafluorophosphate. Grades: Highly Purified. CAS No. 330645-87-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C11H15ClF6N5OP. US Biological Life Sciences.
Worldwide
HCV371
HCV371 is a potent and selective HCV NS5B polymerase inhibitor. It binds the NS5B with an apparent dissociation constant of 150 nM, which leads to high selectivity and lack of cytotoxicity in the antiviral assays. It displayed broad inhibitory activities against the NS5B RdRp enzyme. It showed no inhibitory activity against a panel of human polymerases, including mitochondrial DNA polymerase gamma and other unrelated viral polymerases. Synonyms: HCV-371; HCV 371; HCV371. (R)-2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid. Grades: 98%. CAS No. 675184-27-7. Molecular formula: C18H20N2O3. Mole weight: 312.37.
HCV-IN-4
HCV-IN-4 is a potent and orally bioactive HCV NS5A inhibitor, displaying great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s values of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively. Synonyms: HCV-IN-4|CHEMBL3980210|HY-P0162|CS-0020242. Grades: ≥98% (HPLC). CAS No. 2058080-25-2. Molecular formula: C52H58FN9O8. Mole weight: 956.07.
HC Yellow 13
Heterocyclic Organic Compound. Alternative Names: HC YELLOW 13;HC YELLOW NO. 13; HCYELLOW; 2-[[2-Nitro-4- (trifluoromethyl) phenyl]amino]ethanol; 4- (2-Hydroxyethylamino) -3-nitrobenzotrifluoride. CAS No. 10442-83-8. Molecular formula: C9H9F3N2O3. Mole weight: 250.18. Catalog: ACM10442838.
H-Cys(4-methoxytrityl)-2-chlorotrityl resin
Synonyms: H-Cys(Mmt)-2-ClTrt resin.
H-Cys(Acm)-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: S-acetamidomethyl-L-cysteine-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: 2-Aminoethanethiol-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
It is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: CTTHWGFTLC, CYCLIC; L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide; MMP-2/MMP-9 Inhibitor III; Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor III. Grades: ≥90%. CAS No. 244082-19-7. Molecular formula: C52H71N13O14S2. Mole weight: 1166.33.
H-Cys(Trt)-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: S-Trityl-L-cysteine-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
H-D-3-Pal-OH 2HCl, a synthetic peptide of scientific interest, has the potential to be a promising avenue in the pursuit of new treatments for diseases of varying kinds. Research into the properties of this compound suggests its ability to inhibit cell proliferation and promote apoptosis in oncogenic cells. Interestingly, it may also function as an immunomodulator and possess therapeutic applications towards autoimmune disorders. These findings speak to the complex and multifaceted nature of H-D-3-Pal-OH 2HCl and the implications it could have in furthering scientific understanding of these conditions. Synonyms: (R)-2-Amino-3-(pyridin-3-yl)propanoic acid dihydrochloride; H-D-3-Pal-OH.2HCl; 3-(3-Pyridyl)-D-alanine dihydrochloride. Grades: 95%. CAS No. 93960-21-5. Molecular formula: C8H12Cl2N2O2. Mole weight: 239.10.
HDAC2-IN-2 (compound 124) is an inhibitor of HDAC2 with Kd value of 0.1-1 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 332169-78-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164050.
HDAC3 Inhibitor
HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM, IC50s = 0.95 nM). HDAC3 inhibitors increase histone acetylation and restore normal transcriptional patterns. Treatment with inhibitors primarily targeting HDAC3, including some with additional activity on HDAC1, led to improvement in motor function and working memory in N-terminal transgenic HD mice. Synonyms: Histone Deacetylase 3 Inhibitor; (E) -3-Phenyl-N-[[4- (propylaminocarbamoyl) phenyl]methyl]prop-2-enamide. Grades: ≥98%. CAS No. 2044701-99-5. Molecular formula: C20H23N3O2. Mole weight: 337.4.
HDAC6-IN-23
HDAC6-IN-23 (compound 9) is an orally active HDAC6 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2991427-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156274.
HDAC6-IN-26
HDAC6-IN-26 (compound 23) is a potent inhibitor of HDAC6 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2991427-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157219.
HDAC-IN-1
HDAC-IN-1, an analogue of MC 1568, is a Iia HDACs inhibitor that could probably influence myogenesis and adipogenesis. Uses: Hdac-in-1 is a iia hdacs inhibitor that could probably influence myogenesis and adipogenesis. Synonyms: MC1568; MC 1568; MC-1568; HDAC-IN-1; HDAC IN 1. Grades: 98%. CAS No. 1239610-44-6. Molecular formula: C17H15FN2O3. Mole weight: 314.31.
HDAC-IN-2
HDAC-IN-2, a selective HDAC inhibitor, has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.It is under Phase II trials against Multiple myeloma. IC50: 4 nM and 76 nM for. Uses: Hdac-in-2 is a selective hdac inhibitor that has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.it is under phase ii trials against multiple myeloma. Synonyms: ACY-241; ACY 241; ACY241; HDAC-IN-2; Citarinostat; 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide; UNII-441P620G3P; 441P620G3P; Citarinostat. Grades: 98%. CAS No. 1316215-12-9. Molecular formula: C24H26ClN5O3. Mole weight: 467.95.
HDAC-IN-4
HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1252003-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128763.
HDAC-IN-55
HDAC-IN-55(8j) is a small molecular compound that can increase the expression of E-cadherin and inhibit the proliferation of cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268674-16-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-153607.
HDAC Inhibitor XVII ((E)-N-Hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamide, Histone Deacetylase Inhibitor XVII)
A cell-permeable N-hydroxycinnamide derivative that acts a highly potent and HDAC8-selective histone deacetylase inhibitor (IC50 = 27nM), displaying much reduced or little potency against HDAC1/3 (IC50 = 3.0uM), HDAC2/4/6/10/11 (IC50 >20uM), or total HDAC activity in HeLa nuclear extract (IC50 >10uM). Reported to preferentially inhibit the proliferation of human lung cancer cells CL1-5, H1299, and A549 (IC50 from 7 to 8uM), while being much less toxic to normal human lung IMR-90 cells (73% inhibition at 40uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??NO?, Primary Target IC50: 27nM. US Biological Life Sciences.
Worldwide
HDAC Inhibitor XXIII, Tubastatin A (N-Hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-ylmethyl)benzamide, HCl)
A cell-permeable carbazolohydroxamate compound that acts as a highly potent, reversible and active-site zinc-binding HDAC6 inhibitor with excellent selectivity among other HDAC isozymes (IC50=0.015, 0.854, 16.4uM for HDAC6, HDAC8 and HDAC1, respectively) with no activity towards HDAC2, 3, 4, 7, 9, 10 and 11 (IC50>30uM). Shown to induce a-tubulin hyperacetylation at 2.5uM, and offer complete neuroprotection in primary cortical rat neuronal cells against homocysteic acid (HCA)-induced oxidative stress at 10uM with no noticeable neurotoxicity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: D-alanine-2-chlorotrityl resin. Pack Sizes: 5g, 25g.
H-D-Ala(3-pyridyl)-OH
A reagent used in the synthesis of selective ligands derived from somatostatin antagonists. Synonyms: 3-(3-Pyridyl)-D-alanine; (R)-2-Amino-3-(pyridin-3-yl)propanoic acid. Grades: 95%. CAS No. 70702-47-5. Molecular formula: C8H10N2O2. Mole weight: 166.18.
H-D-Ala-L-Glu-NH2 is a potential impurity of L-alanyl-L-glutamine used for glutamine supplementation. Synonyms: L-Glutamine, D-alanyl-; (S)-5-Amino-2-((R)-2-aminopropanamido)-5-oxopentanoic acid. Grades: HPLC>95%. CAS No. 205252-36-4. Molecular formula: C8H15N3O4. Mole weight: 217.23.
H-D-Ala-OMe hydrochloride
H-D-Ala-OMe hydrochloride is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 14316-06-4. Pack Sizes: 500 g. Product ID: HY-W007986.
HDAOS (N-(2-Hydroxy-3-sulfopropyl)- 3,5-dimethoxyaniline sodium salt
1g Pack Size. Group: Building Blocks, Organics. Formula: C11H16NNaO6S. CAS No. 82692-88-4. Prepack ID 56828280-1g. Molecular Weight 313.3. See USA prepack pricing.
H-D-Asp(OtBu)-OH is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 64960-75-4. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-W015233.
H-D-Asp(OtBu)-OtBu·HCl
H-D-Asp(OtBu)-OtBu·HCl is the isomer of H-Asp(OtBu)-OtBu.HCl (HY-W013291), and can be used as an experimental control. H-Asp(OtBu)-OtBu.HCl is an aspartic acid derivative [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 135904-71-1. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W013291A.
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: S-Trityl-D-cysteine-2-chlorotrityl resin. Pack Sizes: 5g, 25g.