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5g Pack Size. Group: Biochemicals, Fluorinated Products, Peptide Reagents. Formula: C11H16F6N5OP. CAS No. 94790-37-1. Prepack ID 87448736-5g. Molecular Weight 379.24. See USA prepack pricing.
HBV core ? antigen (HBcAg) human
~1 mg protein/mL, 95% (SDS-PAGE), recombinant, expressed in E. coli, clone HBV 320. Group: Fluorescence/luminescence spectroscopy.
HBV-IN-10
HBV-IN-10 is an enantiomer of compound 6 (WO2021204258A1), which is a hepatitis B surface antigen (HBsAg) inhibitor (0.001 μM< EC50 ≤0.05 μM). (Extracted from patent WO2021204258A1, compound 6). Synonyms: (5R,8S)-10-(6-fluoro-4-(3-methoxypyrrolidin-1-yl)pyridin-2-yl)-2-(pyrimidin-2-yl)-6,7,8,9-tetrahydro-5H-5,8-epiminocyclohepta[d]pyrimidine. Grade: ≥98% (HPLC). CAS No. 2716907-16-1. Molecular formula: C23H24FN7O. Mole weight: 433.48.
HBV-IN-11
HBV-IN-11 is a potent inhibitor of HBsAg secretion with an EC50 of 0.46 μM. (Extracted from patent WO2018085619A1, example 28). Synonyms: (S)-2-chloro-7-isopropyl-3-(3-methoxypropoxy)-11-oxo-6,7-dihydro-11H-benzo[f]pyrido[1,2-d][1,4]oxazepine-10-carboxylic acid. Grade: ≥98% (HPLC). CAS No. 2226178-41-0. Molecular formula: C21H24ClNO6. Mole weight: 421.87.
HBV-IN-12
HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg) (0.001 μM< EC50 ≤0.05 μM). It has anti-HBV DNA activity (0.001 μM
HBV-IN-13
HBV-IN-13 is a potent inhibitor of hepatitis B surface antigen (HBsAg). (Extracted from patent WO2021204252A1, compound 1_B). Synonyms: (S)-7-isopropyl-4-(3-methoxypropoxy)-11-oxo-6,11-dihydro-7H-[1,3]dioxolo[4,5-h]pyrido[2,1-a]isoquinoline-10-carboxylic acid. Grade: ≥98% (HPLC). CAS No. 2724228-72-0. Molecular formula: C22H25NO7. Mole weight: 415.44.
HBV-IN-37
HBV-IN-37 is an inhibitor of HBV with an EC 50 value of 10 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 380483-01-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156665.
HBV-IN-4
HBV-IN-4, a potent and orally active inhibitor of HBV DNA replication (IC50 = 14 nM), induces the formation of genome-free capsids and has potent anti-HBV effect. Synonyms: Benzonitrile, 4-[[4-[5-chloro-6-[(2,3-dihydroxypropyl)amino]-2-fluoro-3-pyridinyl]-1-oxo-2(1H)-phthalazinyl]methyl]-. Grade: ≥95%. CAS No. 2305897-84-9. Molecular formula: C24H19ClFN5O3. Mole weight: 479.89.
HBV-IN-6
HBV-IN-6 is a potent inhibitor of HBV with an EC50 of 44 nM. (Extracted from patent WO2021213445A1, compound 3). Synonyms: 2-(4-(5-((3R,5S)-5-((3-chloro-4-fluorophenyl)carbamoyl)-6-methyl-1,1-dioxido-1,2,6-thiadiazinan-3-yl)thiophen-2-yl)phenyl)acetic acid. Grade: ≥98% (HPLC). CAS No. 2724224-47-7. Molecular formula: C23H21ClFN3O5S2. Mole weight: 538.01.
HBV-IN-7
HBV-IN-7 is a potent inhibitor of HBV with an EC50 of 7 nM. (Extracted from patent WO2021213445A1, compound 5). Synonyms: (E)-3-(5-(5-((3-chloro-4-fluorophenyl)carbamoyl)-6-methyl-1,1-dioxido-1,2,6-thiadiazinan-3-yl)thiophen-2-yl)acrylic acid. Grade: ≥98% (HPLC). CAS No. 2724224-49-9. Molecular formula: C18H17ClFN3O5S2. Mole weight: 473.93.
HBV-IN-8
HBV-IN-8 is a potent inhibitor of HBV with an EC50 of 287.9 nM. (Extracted from patent WO2021213445A1, compound 13). Synonyms: 4-Piperidineacetic acid, 1-[5-[5-[[(3-chloro-4-fluorophenyl)amino]carbonyl]tetrahydro-6-methyl-1,1-dioxido-2H-1,2,6-thiadiazin-3-yl]-2-thiazolyl]-. Grade: ≥98% (HPLC). CAS No. 2724224-57-9. Molecular formula: C21H25ClFN5O5S2. Mole weight: 546.04.
HBV-IN-9
HBV-IN-9, a potent HBsAg (HBV Surface antigen) inhibitor (IC50 = 10 nM), is an HBV DNA production inhibitor with an IC50 of 0.15 nM in HepG2.2.15 cells. (Extracted from patent WO2018001952A1, example 20). Synonyms: Pyrido[4,3-d]pyrimidine, 6-[6-fluoro-4-(3-methoxy-1-pyrrolidinyl)-2-pyridinyl]-5,6,7,8-tetrahydro-5-methyl-2-(2-pyrimidinyl)-. Grade: ≥98% (HPLC). CAS No. 2170998-69-1. Molecular formula: C22H24FN7O. Mole weight: 421.47.
HBX 19818
HBX 19818 exhibited a dose-dependent effect on USP7 activity. HBX 19,818 efficiently blocked labeling of USP7 but not that of USP8, USP5, USP10, CYLD, or UCH-L3, showing this compound's specificity for USP7 over a panel of active DUBs under physiological conditions proved to be active in cells, as it almost completely inhibited USP7 labeling at 25 mM. MS/MS spectrum revealed that HBX 19,818 is attached to Cys315. Based on UV chromatogram (l = 332 nm) peak areas, HBX 19,818 partially reverses the deubiquitination of Mdm2 by USP7 in HEK293 cells, confirming that HBX 19,818 inhibits a biological activity of USP7 in living cells. HBX 19,818 has additional off-target, p53-independent proapoptotic effects. Synonyms: HBX19818; HBX-19818. Grade: >98%. CAS No. 1426944-49-1. Molecular formula: C25H28ClN3O. Mole weight: 421.96.
HBX 41108
HBX 41108 is an inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 424 nM). HBX 41108 inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). HBX 41108 stabilizes p53, activates transcription of a p53 target gene without inducing genotoxic stress, and inhibits cancer cell growth. HBX 41108 induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines. Synonyms: HBX 41108; HBX-41108; HBX41108; HBX 41,108; HBX-41,108; HBX41,108. 7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile. Grade: ≥98% by HPLC. CAS No. 924296-39-9. Molecular formula: C13H3ClN4O. Mole weight: 266.64.
HC-030031
HC-030031 is a potent and selective TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC 50 s of 6.2±0.2 and 5.3±0.2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 349085-38-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15064.
HC-030031
HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively. Synonyms: HC-030031; HC 030031; HC030031. TOSLAB 829227. Grade: >98%. CAS No. 349085-38-7. Molecular formula: C18H21N5O3. Mole weight: 355.39.
A TRPA1 (transient receptor potential) selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Group: Biochemicals. Alternative Names: 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide; TrpA1 Antagonist. Grades: Highly Purified. CAS No. 349085-38-7. Pack Sizes: 10mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
HC-056456
HC-056456 is an effective but not perfectly-selective blocker of CatSper channels. The [Na+]i rise is slowed by HC-056456 (IC50~3 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide. CAS No. 7733-96-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112729.
HC 067047
HC 067047. Group: Biochemicals. Grades: Purified. CAS No. 883031-03-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
HC-067047
HC-067047 is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC 50 values of 48 nM, 133 nM, and 17 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 883031-03-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100208.
HC-067047
HC-067047 is a potent and selective TRPV4 antagonist. It has been shown to increase functional bladder capacity and to reduce micturition frequency in wild-type mice and rats with cystitis. HC-067047 also attenuated allodynia in diabetic mice, suggesting its potential application for the treatment of painful diabetic neuropathy (PDN). Synonyms: HC 067047; HC067047; 2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide. Grade: ≥98%. CAS No. 883031-03-6. Molecular formula: C26H28F3N3O2. Mole weight: 471.5.
HC 067047 hydrochloride
HC-067047 is a potent and selective TRPV4 antagonist. It has been shown to increase functional bladder capacity and to reduce micturition frequency in wild-type mice and rats with cystitis. HC-067047 also attenuated allodynia in diabetic mice, suggesting its potential application for the treatment of painful diabetic neuropathy (PDN). Synonyms: 2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide hydrochloride. CAS No. 1481646-76-7. Molecular formula: C26H29ClF3N3O2. Mole weight: 507.98.
HC-5404-Fu
HC-5404-Fu is a PERK inhibitor with an antitumor activity. HC-5404-Fu inhibits endoplasmic reticulum stress response signalling. HC-5404-Fu sensitizes renal cell carcinoma cells to vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitors ( TKIs ). HC-5404-Fu is promising for research of renal cell carcinoma, gastric cancer, metastatic breast cancer, small cell lung cancer, and other solid tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3034479-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-157231A.
HC-7366
HC-7366 (compound 3) has GCN2 inhibitory activity, with the IC 50 value less than 0.05 μM. HC-7366 plays an important role in anti-tumor research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GCN2 modulator-1. CAS No. 2803470-63-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160196.
Hc-AFP1
Hc-AFP1 is an antimicrobial peptide produced by Heliophila coronopifolia (South African Brassicaceae species). It has antifungal activity. Synonyms: Arg-Tyr-Cys-Glu-Arg-Ser-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Ser-Gly-Lys-Cys-Ser-Asn-Gln-Cys-Gln-Arg-Leu-Glu-Gly-Ala-Ala-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Tyr-Pro-Cys (Disulfide bridge: Cys3-Cys50, Cys14-Cys35, Cys20-Cys44, Cys24-Cys46). Grade: >98%. Molecular formula: C229H335N71O71S8. Mole weight: 5475.11.
Hc-AFP2
Hc-AFP2 is an antimicrobial peptide produced by Heliophila coronopifolia (South African Brassicaceae species). It has antifungal activity. Synonyms: Gln-Lys-Leu-Cys-Glu-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Asn-Ala-Cys-Arg-Asn-Gln-Cys-Ile-Asn-Leu-Glu-Lys-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys (Disulfide bridge: Cys4-Cys51, Cys15-Cys36, Cys21-Cys45, Cys25-Cys47). Grade: >98%. Molecular formula: C242H364N76O70S8. Mole weight: 5714.52.
Hc-AFP3
Hc-AFP3 is an antimicrobial peptide produced by Heliophila coronopifolia (South African Brassicaceae species). It has antifungal activity. Synonyms: Arg-Tyr-Cys-Glu-Arg-Ser-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Thr-Asp-Lys-Cys-Ser-Ser-Gln-Cys-Gln-Arg-Leu-Glu-Gly-Ala-Ala-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Tyr-Pro-Cys (Disulfide bridge: Cys3-Cys50, Cys14-Cys35, Cys20-Cys44, Cys24-Cys46). Grade: >98%. Molecular formula: C231H338N70O73S8. Mole weight: 5520.14.
Hc-AFP4
Hc-AFP4 is an antimicrobial peptide produced by Heliophila coronopifolia (South African Brassicaceae species). It has antifungal activity. Synonyms: Gln-Lys-Leu-Cys-Glu-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Gly-Ala-Cys-Arg-Asn-Gln-Cys-Ile-Arg-Leu-Glu-Arg-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys (Disulfide bridge: Cys4-Cys51, Cys15-Cys36, Cys21-Cys45, Cys25-Cys47). Grade: >98%. Molecular formula: C242H367N79O68S8. Mole weight: 5727.56.
hCAII-IN-8
hCAII-IN-8 is a potent and selective inhibitor of carbonic anhydrase (CA). Synonyms: Compound CDy9. CAS No. 952306-80-8. Molecular formula: C15H16N2O5S. Mole weight: 336.4.
hCAIX-IN-5
hCAIX-IN-5 is a Carbonic anhydrase IX (hCAIX) inhibitor. Synonyms: TS-09247. Grade: 98% by HPLC. CAS No. 2451479-57-3. Molecular formula: C18H12FNO3. Mole weight: 309.3.
Hc blue 7
Hc blue 7. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-AMINO-6-METHOXY-2-METHYLAMINO-PYRIDINE, DIHYDROCHLORIDE SPECIALITY CHEMICALS;6-methoxy-N2-methylpyridine-2,3-diamine dihydrochloride;3-AMINO-2-METHYLAMINO-6-METHOXYPYRIDINE 2HCL;3-AMINO-2-METHYLAMINO-6-METHOXYPYRIDINE DIHYDROCHLORIDE;3-amino-2-methylam. Product Category: Heterocyclic Organic Compound. Appearance: reddish violet to brown powder. CAS No. 83732-72-3. Molecular formula: C7H11N3O?2(HCl). Mole weight: 226.1. Purity: 0.96. IUPACName: 6-methoxy-2-N-methylpyridine-2,3-diamine dihydrochloride. Product ID: ACM83732723. Alfa Chemistry ISO 9001:2015 Certified.
HCC-1 (CCL14) (66 aa) human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
HCC-1 (CCL14) (72 aa) human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
hCG1811882
hCG1811882.
HCGRP-(8-37)
HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. Uses: Scientific research. Group: Peptides. Alternative Names: Human ?-CGRP (8-37). CAS No. 119911-68-1. Pack Sizes: 500 ?g; 1 mg; 5 mg; 10 mg. Product ID: HY-P1014.
HCGRP-(8-37) acetate
HCGRP-(8-37) acetate is the human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP1 receptors. Synonyms: H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2.CH3CO2H; L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-valyl-L-valyl-L-lysyl-L-asparagyl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-lysyl-L-alanyl-L-phenylalaninamide acetic acid; Human alpha-CGRP (8-37) acetate; 8-37-α-Calcitonin gene-related peptide (human) acetate; Human calcitonin gene-related peptide (8-37) acetate; Human CGRP(8-37) acetate; Human α-calcitonin gene-related peptide(8-37) acetate; Human α-CGRP (8-37) acetate. Grade: ≥95%. Molecular formula: C141H234N44O40. Mole weight: 3185.64.
HCH6-1
HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1435265-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101283.
HCH6-1
HCH6-1 is a dipeptide antagonist of formyl peptide receptor 1 (FPR1). HCH6-1 has the potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases. Synonyms: Methyl benzoyl-L-tryptophyl-D-phenylalaninate. CAS No. 1435265-06-7. Molecular formula: C28H27N3O4. Mole weight: 469.53.
H-Cha-ol-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cha-ol-Trt(2-Cl)-Resin; H-Cha-ol-Barlos Resin; L-3-Cyclohexylalaninol 2-chlorotrityl resin.
H-Chg-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cit-Trt(2-Cl)-Resin; H-Cit-Barlos Resin; L-γ-Carbamoyl-ornithine 2-chlorotrityl resin.
Hck is a member of the Src family of non-receptor associated protein tyrosine kinases (PTK). Hck has been shown to associate with and be activated by Bcr-Abl, which is a protein-tyrosine kinase that is expressed in chronic myelogenous leukemia. Group: Enzymes. Synonyms: Hck; HCK; tyrosine-protein kinase HCK; JTK9; p59Hck; p61Hck. Hck. Mole weight: mol wt 58 kDa. Storage: -70°C. Form: buffered aqueous glycerol solution; Solution in 50 mM Tris pH 7.5, containing 0.05 mM EDTA, 1mM DTT, 100 mM NaCl, 0.05% NP-40, and 50% glycerol. Source: Baculovirus infected insect cells. Species: Human. Hck; HCK; tyrosine-protein kinase HCK; JTK9; p59Hck; p61Hck. Cat No: NATE-0334.
Hck-IN-1 is a selective inhibitor of Nef-dependent Hck with IC50s of 2.8 and >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide antagonist of HIV-1 Nef with an IC50 of 100-300 nM for wild-type HIV-1 replication. It binds pocket residue Asn126 and has anti-retroviral activity. Synonyms: Nef-IN-B9; (E)-4-((3-Chlorophenyl)diazenyl)-5-hydroxy-3-(4-nitrophenyl)-1H-pyrazole-1-carbothioamide; 1H-Pyrazole-1-carbothioamide, 4-[(1E)-2-(3-chlorophenyl)diazenyl]-5-hydroxy-3-(4-nitrophenyl)-. Grade: ≥98%. CAS No. 1473404-51-1. Molecular formula: C16H11ClN6O3S. Mole weight: 402.81.
Hcl-hst5
Hcl-hst5 has antifungal activity and it was found in Nomascus leucogenys. Rich in histidines. Grade: >97% by HPLC.
HCN4 Control Peptide (Hyperpolarization-activated Cyclic Nucleotide-gated Potassium Channel 4)
HCN4 Control Peptide (Hyperpolarization-activated Cyclic Nucleotide-gated Potassium Channel 4). Group: Molecular Biology. Pack Sizes: 120ug. US Biological Life Sciences.
Worldwide
HCoV-229E-IN-1
HCoV-229E-IN-1 is a potent HCoV-229E replication inhibitor, with an EC50 value of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively. Synonyms: HCoV-229E-IN-1|CHEMBL4854936|HY-132169|CS-0163711. Grade: 99%. Molecular formula: C38H53N3O2. Mole weight: 583.85.
HCoV-229E-IN-1
HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC 50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2639757-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132169.
HCoV-OC43-IN-1
HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC 50 : 90 nM). HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2809363-81-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156346.
HCPI
HCPI. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[4-(Hydrazinocarbonyl)phenyl]-4,5-diphenylimidazole. Product Category: Other Fluorophores. Appearance: Solid. CAS No. 151589-38-7. Molecular formula: C22H18N4O. Mole weight: 354.4. Purity: 90%+. IUPACName: 4-(4,5-diphenyl-1H-imidazol-2-yl)benzohydrazide. Canonical SMILES: C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C(=O)NN)C4=CC=CC=C4. Product ID: ACM151589387-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: H. C. Pitney Variety Store Building.
HCT-116 Transfection Reagent
Transfection Reagent for HCT116 Colon Carcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6812.
Nevada, Texas, USA
hCT (Calcitonin), Human
It is a cell-penetrating peptide (CPP) derived from the human calcitotnin protein sequence. It has good proteolytic resistance and can permeate cell membrane without significant influence at low micromolar concentration. hCT can be conjugated with large molecules and used as a drug delivery vehicle. Synonyms: H-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val-Gly-Ala-Pro-OH. Grade: >98%. Molecular formula: C121H176N30O35. Mole weight: 2610.91.
HC Toxin
HC Toxin is a cell-permeable histone deacetylase (HDAC) inhibitor (IC50 = 30 nM) that inhibits HDACs in maize, Physarum and chicken. HC Toxin is metabolized from H. carbonum (now C. carbonum), and displays antifungal and antiproliferative effects. Synonyms: Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine); Cyclo(aoe-pro-ala-ala). Grade: ≥95%. CAS No. 83209-65-8. Molecular formula: C21H32N4O6. Mole weight: 436.50.
HC-Toxin
HC-Toxin, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC 50 of 30 nM [1]. HC-Toxin induces tumor cell apoptosis and has anticancer effects [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83209-65-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-126856.
Aminium-based coupling reagent, analogous to HBTU, which in comparative studies was found to give superior results to TBTU in the synthesis of difficult peptides, in hindered couplings, and cyclizations. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9.
Luxembourg Bio Technologies
HCTU
HCTU. Group: Biochemicals. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N,N,N',N'-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium hexafluorophosphate; 1-[Bis (dimethylamino) methylen]-5-chlorobenzotriazolium 3-oxide hexafluorophosphate. Grades: Highly Purified. CAS No. 330645-87-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C11H15ClF6N5OP. US Biological Life Sciences.
Worldwide
HCTU
HCTU is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W010951.
HCV371
HCV371 is a potent and selective HCV NS5B polymerase inhibitor. It binds the NS5B with an apparent dissociation constant of 150 nM, which leads to high selectivity and lack of cytotoxicity in the antiviral assays. It displayed broad inhibitory activities against the NS5B RdRp enzyme. It showed no inhibitory activity against a panel of human polymerases, including mitochondrial DNA polymerase gamma and other unrelated viral polymerases. Synonyms: HCV-371; HCV 371; HCV371. (R)-2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid. Grade: 98%. CAS No. 675184-27-7. Molecular formula: C18H20N2O3. Mole weight: 312.37.
HCV-IN-29
HCV-IN-29 is an inhibitor of hepatitis C virus (HCV). (Exacted from patent US8329159B2, compound 1e). Synonyms: 4,4'-Bis(2-((S)-pyrrolidin-2-yl)-1H-imidazol-5-yl)-1,1'-biphenyl tetrahydrochloride; 5,5'-[1,1'-Biphenyl]-4,4'-diylbis[2-(2S)-2-pyrrolidinyl-1H-imidazole] Hydrochloride; 5,5'-(4,4'-Biphenyldiyl)bis{2-[(2S)-2-pyrrolidinyl]-1H-imidazole} tetrahydrochloride. Grade: ≥98% (HPLC). CAS No. 1009119-83-8. Molecular formula: C26H32Cl4N6. Mole weight: 570.38.
HCV-IN-3
HCV-IN-3 is an inhibitor of hepatitis C virus (HCV) NS3/4a protein, with an IC50 of 20 μM and a Kd of 29 μM. Synonyms: 2,4-Difluoro-3-phenoxybenzenemethaneamine; Benzenemethanamine, 2,4-difluoro-3-phenoxy-; 1-(2,4-Difluoro-3-phenoxyphenyl)methanamine. Grade: ≥95%. CAS No. 1401839-25-5. Molecular formula: C13H11F2NO. Mole weight: 235.23.