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hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with anti-inflammatory effect. Synonyms: (2Z)-N-Biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide; (2Z)-N-(4-Biphenylyl)-2-cyano-3-hydroxy-2-butenamide; 2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy-, (2Z)-; (2Z)-2-cyano-3-hydroxy-N-(4-phenylphenyl)but-2-enamide. Grade: ≥95%. CAS No. 1173715-42-8. Molecular formula: C17H14N2O2. Mole weight: 278.31.
hDHODH-IN-1
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173715-42-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135658.
hDHODH-IN-13
hDHODH-IN-13 (compound w2) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC 50 value of 173.4 nM. hDHODH-IN-13 can be used in the research of IBD [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3032611-13-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149642.
hDHODH-IN-2
hDHODH-IN-2, an analogue of the active metabolite of Leflunomide, is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with anti-inflammatory activity. Synonyms: (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide; (2Z)-N-(4-Biphenylyl)-2-cyano-3-cyclopropyl-3-hydroxyacrylamide; 2-Propenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-cyclopropyl-3-hydroxy-, (2Z)-; (Z)-N-Biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxy-acrylamide; (Z)-N-([1,1'-biphenyl]-4-yl)-2-cyano-3-cyclopropyl-3-hydroxyacrylamide. Grade: ≥95%. CAS No. 183946-00-1. Molecular formula: C19H16N2O2. Mole weight: 304.34.
hDHODH-IN-3
hDHODH-IN-3, a human dihydroorotate dehydrogenase inhibitor, inhibits measles virus replication with a pMIC50 of 8.6. Synonyms: DHODH-IN-2; 2-[4-(2-Bromophenoxy)-3-ethoxy-5-methyl-1H-pyrazol-1-yl]-5-ethylpyrimidine; Pyrimidine, 2-[4-(2-bromophenoxy)-3-ethoxy-5-methyl-1H-pyrazol-1-yl]-5-ethyl-. Grade: ≥95%. CAS No. 1644156-80-8. Molecular formula: C18H19BrN4O2. Mole weight: 403.27.
hDHODH-IN-3
hDHODH-IN-3 (compound 21d) is a human dihydroorotate dehydrogenase (HsDHODH) inhibitor, inhibits measles virus replication with a pMIC 50 value of 8.6 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1644156-80-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135570.
hDHODH-IN-4
hDHODH-IN-4 is a potent inhibitor of human dihydroorotate dehydrogenase (DHODH), with a pIC50 of 7.8 for human recombinant DHODH. It inhibits measles virus replication, with a pMIC50 of 8.8. Synonyms: [1-(5-Cyclopropyl-2-pyrimidinyl)-3-isopropoxy-5-methyl-1H-pyrazol-4-yl](phenyl)methanol; 1H-Pyrazole-4-methanol, 1-(5-cyclopropyl-2-pyrimidinyl)-5-methyl-3-(1-methylethoxy)-α-phenyl-; DHODH-IN-5. Grade: ≥95%. CAS No. 1644156-56-8. Molecular formula: C21H24N4O2. Mole weight: 364.44.
hDHODH-IN-5
DHODH-IN-7, a human dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = 0.91 μM), induces differentiation in acute myeloid leukemia. Synonyms: N-{3-Oxo-3-[(1R)-1,2,3,4-tetrahydro-1-naphthalenylamino]propyl}-4-(trifluoromethyl)benzamide; Benzamide, N-[3-oxo-3-[[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]propyl]-4-(trifluoromethyl)-; N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-3-{[4-(trifluoromethyl)phenyl]formamido}propanamide. Grade: ≥95%. CAS No. 2029049-77-0. Molecular formula: C21H21F3N2O2. Mole weight: 390.40.
H-D-HoPhe-OH·HCl. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
H-D-Ile-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Ile-Trt(2-Cl)-Resin; H-D-Ile-Barlos Resin; D-Isoleucine 2-chlorotrityl resin.
H-D-Ile-asp-oh
H-D-Ile-asp-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-D-ILE-ASP-OH. Product Category: Heterocyclic Organic Compound. CAS No. 120067-35-8. Molecular formula: C10H18N2O5. Mole weight: 246.26. Product ID: ACM120067358. Alfa Chemistry ISO 9001:2015 Certified.
HDITCperchlorate
HDITCperchlorate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1',3,3,3',3'-HEXAMETHYL-4,4',5,5'-DI-BENZO-2,2'-INDOTRICARBOCYANINE PERCHLORATE;1h-benz[e]indolium,2-[7-(1,3-dihydro-1,1,3-trimethyl-2h-benz[e]indol-2-ylidene;3,5-heptatrienyl]-1,1,3-trimethyl-)-perchlorate;2-[7-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]i. Product Category: Photonic and Optical Device. Appearance: DARK GREEN FINE POWDER. CAS No. 23178-67-8. Molecular formula: C37H37ClN2O4. Mole weight: 609.15. Product ID: ACM23178678. Alfa Chemistry ISO 9001:2015 Certified.
HDL376
HDL376 is a scavenger receptor BI inhibitor. Synonyms: N-(5-Chloro-2-methylphenyl)-N'-(2-methylpropyl)thiourea; 1-(5-Chloro-2-methylphenyl)-3-isobutylthiourea; Thiourea, N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)-; SDZ-HDL 376; HDL 376; HDL-376. Grade: ≥95%. CAS No. 147751-31-3. Molecular formula: C12H17ClN2S. Mole weight: 256.79.
H-Dl-ala-oet · hcl
H-Dl-ala-oet · hcl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-DL-Ala-OEt. HCl;2-Amino-propionic acid ethyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 17344-99-9. Molecular formula: C5H11NO2·HCl. Mole weight: 153.61. Product ID: ACM17344999. Alfa Chemistry ISO 9001:2015 Certified.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Leu-Trt(2-Cl)-Resin; H-D-Leu-Barlos Resin; D-Leucine 2-chlorotrityl resin.
H-D-LEU-D-LEU-OH
A substrate for D-peptidase S. Synonyms: D-leucyl-D-leucine; N-D-Leucyl-D-leucine; (R)-2-((R)-2-Amino-4-methylpentanamido)-4-methylpentanoic acid. CAS No. 38689-30-4. Molecular formula: C12H24N2O3. Mole weight: 244.33.
H-Dl-ser-ome.hcl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Methyl-DL-serine hydrochloride;DL-Ser-OMe.HCl;DL-Serine methyl ester hydrochloride;H-DL-Ser-OMe. HCl. Product Category: Heterocyclic Organic Compound. CAS No. 5619-4-5. Molecular formula: C4H9NO3.HCl. Product ID: ACM1358433. Alfa Chemistry ISO 9001:2015 Certified. Categories: Methyl DL-serinate HCl.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Lys(Boc)-Trt(2-Cl)-Resin; H-D-Lys(Boc)-Barlos Resin; N-ε-(t-Butoxycarbonyl)-D-lysine 2-chlorotrityl resin.
N6-[(Phenylmethoxy)carbonyl]-D-lysine is a protected amino acid. It can be used for the synthesis of Chrysobactin [N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine], acting as a siderophore. Synonyms: Nε-Z-D-lysine; D-LYSINE(CBZ); H-D-Lys(Cbz)-OH; Nepsilon-carbobenzyloxy-D-lysine; D-LYSINE(Z)-OH; N-e-CBZ-D-Lysine. Grade: ≥ 98% (HPLC). CAS No. 34404-32-5. Molecular formula: C14H20N2O4. Mole weight: 280.30.
The Hdm2 E3 Ligase Inhibitor, also referenced under CAS 414905-09-2, controls the biological activity of Hdm2 E3 Ligase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable pyrimidoquinoline-dione compound that acts as an efficient Hdm2 E3 ligase inhibitor, prevents Hdm2-mediated p53 ubiquitination and increases the cellular levels of both p53 and Hdm2 (IC50 ~3uM in RPE cells). Shown to selectively arrest the growth of several tumor cells in a p53-dependent manner and display desirable aqueous solubility. Group: Biochemicals. Grades: Highly Purified. CAS No. 502137-98-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Hdm2 E3 Ligase Inhibitor II, HLI373 - CAS 502137-98-6
The Hdm2 E3 Ligase Inhibitor II, HLI373, also referenced under CAS 502137-98-6, controls the biological activity of Hdm2 E3 Ligase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
HDMA
Increased coupling efficiency and lower racemization compared to HATU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1- [ (Dimethylamino) (Morpholino) Methylene] -1H-[1,2,3]triazolo[4,5-b]pyridine-1-ium 3-oxide hexafluorophosphate. CAS No. 958029-37-3. Registered patent of Luxembourg Bio Technologies.
Luxembourg Bio Technologies
HDMAPP triammonium salt
HDMAPP is a photo-crosslinkable biotin derivative that targets the HMBPP Site of BTN3A1, and activates Vγ9Vδ2 T cells, which plays a key role in the cross talk of the innate and adaptive immune system. Synonyms: HMBPP triammonium; [[(E)-4-hydroxy-3-methylbut-2-enoxy]-oxidophosphoryl] phosphate triammonium salt. Grade: ≥90%. CAS No. 443892-56-6. Molecular formula: C5H9O8P2·3NH4. Mole weight: 313.2.
HDMC
Aminium-type coupling reagent derived from dimethylmorpholino urea. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 6-chloro-1- ( (Dimethylamino) (Morpholino) -methylene)-1H-benzotriazolium hexafluorophosphate 3-oxide. CAS No. 1082951-62-9. Registered patent of Luxembourg Bio Technologies.
Luxembourg Bio Technologies
HDMC
HDMC. Group: Biochemicals. Alternative Names: 6-HDMCB; N-[(5-Chloro-3-oxido-1H-benzotriazol-1-yl)-4-morpholinylmethylene]-N-methylmethanaminium hexafluorophosphate. Grades: Highly Purified. CAS No. 1082951-62-9. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H17ClF6N5O2P. US Biological Life Sciences.
Worldwide
HDMC
HDMC is a reagent used in preparation of COMU as a more effective peptide coupling reagent than benzotriazole-based uronium compounds in peptide synthesis. Synonyms: HDMC; 6-HDMCB; (5-Chloro-3-oxo-1H-1lambda-5,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphate; SCHEMBL21223097; DTXSID00746375; BCP29166; N-[(5-Chloro-3-oxido-1H-benzotriazol-1-yl)-4-morpholinylmethylene]-N-methylmethanaminium hexafluorophosphate. Grade: > 95 % (HPLC). CAS No. 1082951-62-9. Molecular formula: C13H17ClF6N5O2P. Mole weight: 455.72.
H-D-Met-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Met-Trt(2-Cl)-Resin; H-D-Met-Barlos Resin; D-Methionine 2-chlorotrityl resin.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Nle-Trt(2-Cl)-Resin; H-D-Nle-Barlos Resin; D-Norleucine 2-chlorotrityl resin.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Nva-Trt(2-Cl)-Resin; H-D-Nva-Barlos Resin; D-Norvaline 2-chlorotrityl resin.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Pen(Acm)-Trt(2-Cl)-Resin; H-D-Pen(Acm)-Barlos Resin; S-Acetamidomethyl-D-penicillamine 2-chlorotrityl resin.
H-D-Pen(Trt)-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Pen(Trt)-Trt(2-Cl)-Resin; H-D-Pen(Trt)-Barlos Resin; S-Trityl-D-penicillamine 2-chlorotrityl resin.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.