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| Product | Description | |
|---|---|---|
| HCV-IN-30 | HCV-IN-30 is an inhibitor of HCV NS5A replication complex with IC50s of 901 and 102 nM against genotypes 1a and 1b replicons, respectively. Synonyms: (2S,2'S)-Di-tert-butyl 2,2'-(5,5'-([1,1'-biphenyl]-4,4'-diyl)bis(1H-imidazole-5,2-diyl))bis(pyrrolidine-1-carboxylate); Bis(2-methyl-2-propanyl) (2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate); (2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis-1-pyrrolidinecarboxylic acid 1,1'-bis(1,1-dimethylethyl) ester; 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis-, 1,1'-bis(1,1-dimethylethyl) ester, (2S,2'S)-. Grade: ≥98% (HPLC). CAS No. 1007882-23-6. Molecular formula: C36H44N6O4. Mole weight: 624.77. |  |
| HCV-IN-31 | HCV-IN-31 is an inhibitor of HCV, with an EC50/EC95 of 15.7 μM for HCV replicon. Synonyms: (2R,3R,4R,5R)-5-(2-amino-6-(methylamino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol; Adenosine, 2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-, (2'R)-; 2-Amino-2'-deoxy-2'-fluoro-N,2'-dimethyladenosine. Grade: ≥95%. CAS No. 1998705-62-6. Molecular formula: C12H17FN6O3. Mole weight: 312.30. | |
| HCV-IN-4 | HCV-IN-4 is a potent and orally bioactive HCV NS5A inhibitor, displaying great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s values of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively. Synonyms: HCV-IN-4|CHEMBL3980210|HY-P0162|CS-0020242. Grade: ≥98% (HPLC). CAS No. 2058080-25-2. Molecular formula: C52H58FN9O8. Mole weight: 956.07. | |
| HCV-IN-7 | HCV-IN-7, a potent and orally active pan-genotypic HCV NS5A inhibitor (IC50 of 3-47 pM) with antiviral activity, demonstrates superior pan-genotypic profile and good pharmacokinetic characteristics, as well as favorable liver uptake. Synonyms: Methyl [(2S)-1-{(2S)-2-[5-(2-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-pyrrolidinyl]-1H-imidazol-5-yl}naphtho[1,2-b]thiophen-7-yl)-1H-imidazol-2-yl]-1-pyrrolidinyl}-3-methyl-1-oxo-2-butanyl]carbamate; Carbamic acid, N,N'-[naphtho[1,2-b]thiene-2,7-diylbis[1H-imidazole-5,2-diyl(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, dimethyl ester. Grade: ≥95%. CAS No. 1449756-86-8. Molecular formula: C40H48N8O6S. Mole weight: 768.92. | |
| HCV-IN-7 dihydrochloride | HCV-IN-7 hydrochloride, a potent and orally active pan-genotypic HCV NS5A inhibitor (IC50 of 3-47 pM) with antiviral activity, demonstrates superior pan-genotypic profile and good pharmacokinetic characteristics, as well as favorable liver uptake. Synonyms: Methyl [(2S)-1-{(2S)-2-[5-(2-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-pyrrolidinyl]-1H-imidazol-5-yl}naphtho[1,2-b]thiophen-7-yl)-1H-imidazol-2-yl]-1-pyrrolidinyl}-3-methyl-1-oxo-2-butanyl]carbamate dihydrochloride; Carbamic acid, N,N'-[naphtho[1,2-b]thiene-2,7-diylbis[1H-imidazole-5,2-diyl(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, dimethyl ester, hydrochloride (1:2). Grade: ≥95%. CAS No. 1449756-87-9. Molecular formula: C40H50Cl2N8O6S. Mole weight: 841.85. | |
| HCVP-IN-1 | HCVP-IN-1 is an inhibitor of hepatitis C viral polymerase (HCVP). Synonyms: Pf-868554; 2-[4-(2-{(2R)-2-Cyclopentyl-5-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl}ethyl)-2-fluorophenyl]-2-methylpropanenitrile; Benzeneacetonitrile, 4-[2-[(2R)-2-cyclopentyl-5-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-3,6-dihydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-2-fluoro-α,α-dimethyl-; (R)-2-(4-(2-(2-cyclopentyl-5-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-2-fluorophenyl)-2-methylpropanenitrile. Grade: 95%. CAS No. 877225-09-7. Molecular formula: C30H34FN5O3. Mole weight: 531.62. | |
| H-Cys-4-abz-met-oh | H-Cys-4-abz-met-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-CYS-4-ABZ-MET-OH;FTASE INHIBITOR II;CYSTEINE-(4-AMINOBENOZYL)METHIONINE. Product Category: Heterocyclic Organic Compound. CAS No. 156707-43-6. Molecular formula: C15H21N3O4S2. Mole weight: 371.47. Product ID: ACM156707436. Alfa Chemistry ISO 9001:2015 Certified. |  |
| H-Cys(4-methoxytrityl)-2-chlorotrityl resin | H-Cys(4-methoxytrityl)-2-chlorotrityl resin. Synonyms: H-Cys(Mmt)-2-ClTrt resin. | |
| H-Cys(Acm)-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Cys(Acm)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: S-acetamidomethyl-L-cysteine-2-chlorotrityl resin. Pack Sizes: 5g, 25g. |  |
| H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH | H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH. Synonyms: H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH. CAS No. 166184-23-2. Molecular formula: C41H61N13O15S2. Mole weight: 1040.15. | |
| H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2 | H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2. Synonyms: Cdpgyigsr-NH2; Laminin peptide 11; Cystinyl-aspartyl-prolyl-glycyl-tyrosyl-isoleucyl-glycyl-seryl-arginyl-NH2; Laminin β-1 Chain (925-933) amide (human, mouse). CAS No. 110590-61-9. Molecular formula: C40H63N13O13S. Mole weight: 966.07. | |
| H-Cys(bzl)-gly-oh | H-Cys(bzl)-gly-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-CYS(BZL)-GLY-OH;S-BENZYL-L-CYSTEINYL-GLYCINE. Product Category: Heterocyclic Organic Compound. CAS No. 7669-84-3. Molecular formula: C12H16N2O3S. Mole weight: 268.33. Product ID: ACM7669843. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Cys(bzl)-obzl.hcl | H-Cys(bzl)-obzl.hcl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-Cys(Bzl)-OBzl.HCl. Product Category: Heterocyclic Organic Compound. CAS No. 4561-11-9. Molecular formula: C17H20ClNO2S. Mole weight: 337.86. Purity: 0.96. IUPACName: benzyl (2R)-2-amino-3-benzylsulfanylpropanoate;hydrochloride. Canonical SMILES: C1=CC=C(C=C1)COC(=O)C(CSCC2=CC=CC=C2)N.Cl. Product ID: ACM4561119. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Cys(CH3Bzl)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(CH3Bzl)-Trt(2-Cl)-Resin; H-Cys(CH3Bzl)-Barlos Resin; S-(4-Methylbenzyl)-L-cysteine 2-chlorotrityl resin. | |
| H-Cys(Et)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(Et)-Trt(2-Cl)-Resin; H-Cys(Et)-Barlos Resin; S-Ethyl-L-cysteine 2-chlorotrityl resin. | |
| H-Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys-OH | H-Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys-OH. Molecular formula: C30H55N15O11S2. Mole weight: 865.98. | |
| H-Cys(MeOBzl)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(MeOBzl)-Trt(2-Cl)-Resin; H-Cys(MeOBzl)-Barlos Resin; S-(4-Methoxybenzyl)-L-cysteine 2-chlorotrityl resin. | |
| H-Cys(Npys)-D-Ala-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2 | H-Cys(Npys)-D-Ala-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2. Synonyms: Cys(Npys)-Ala-(D-Arg)9; D-Argininamide, 3-[(3-nitro-2-pyridinyl)dithio]-L-alanyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-; 3-[(3-Nitro-2-pyridinyl)dithio]-L-alanyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide. Grade: ≥95%. CAS No. 1676104-79-2. Molecular formula: C65H123N41O13S2. Mole weight: 1751.07. | |
| H-Cys-ser-cys-lys-asp-met-thr-asp-lys-glu-cys-leu-asn-phe-cys-his-gln-asp-val-ile-trp-oh | H-Cys-ser-cys-lys-asp-met-thr-asp-lys-glu-cys-leu-asn-phe-cys-his-gln-asp-val-ile-trp-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SARAFOTOXIN A;SARAFOTOXIN A (ATRACTASPIS ENGADDENSIS);SARAFOTOXIN S6A;SARAFOTOXIN S6A1;SARAFOTOXIN S6A (ATRACTASPIS ENGADDENSIS);H-CYS-SER-CYS-LYS-ASP-MET-THR-ASP-LYS-GLU-CYS-LEU-ASN-PHE-CYS-HIS-GLN-ASP-VAL-ILE-TRP-OH;CYS-SER-CYS-LYS-ASP-MET-THR-ASP-LYS-. Product Category: Heterocyclic Organic Compound. CAS No. 126738-34-9. Molecular formula: C105H156N28O34S5. Mole weight: 2514.85. Purity: 0.96. IUPACName: Sarafotoxin S6a. Product ID: ACM126738349. Alfa Chemistry ISO 9001:2015 Certified. | |
| H-Cys(tBu)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(tBu)-Trt(2-Cl)-Resin; H-Cys(tBu)-Barlos Resin; S-(t-Butyl)-L-cysteine 2-chlorotrityl resin. | |
| H-Cysteamine-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: 2-Aminoethanethiol-2-chlorotrityl resin. Pack Sizes: 5g, 25g. | |
| H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (Disulfide bond) | It is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: CTTHWGFTLC, CYCLIC; L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide; MMP-2/MMP-9 Inhibitor III; Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor III. Grade: ≥90%. CAS No. 244082-19-7. Molecular formula: C52H71N13O14S2. Mole weight: 1166.33. | |
| H-Cys(Trt)-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Cys(Trt)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: S-Trityl-L-cysteine-2-chlorotrityl resin. Pack Sizes: 5g, 25g. | |
| H-D-2-Nal-OH HCl | H-D-2-Nal-OH HCl. Synonyms: 3-(2-Naphthyl)-D-alanine hydrochloride; (R)-2-Amino-3-(naphthalen-2-yl)propanoic acid hydrochloride. Grade: 95%. CAS No. 122745-11-3. Molecular formula: C13H13NO2·HCl. Mole weight: 251.8. | |
| H-D-3-Pal-OH 2HCl | H-D-3-Pal-OH 2HCl, a synthetic peptide of scientific interest, has the potential to be a promising avenue in the pursuit of new treatments for diseases of varying kinds. Research into the properties of this compound suggests its ability to inhibit cell proliferation and promote apoptosis in oncogenic cells. Interestingly, it may also function as an immunomodulator and possess therapeutic applications towards autoimmune disorders. These findings speak to the complex and multifaceted nature of H-D-3-Pal-OH 2HCl and the implications it could have in furthering scientific understanding of these conditions. Synonyms: (R)-2-Amino-3-(pyridin-3-yl)propanoic acid dihydrochloride; H-D-3-Pal-OH.2HCl; 3-(3-Pyridyl)-D-alanine dihydrochloride. Grade: 95%. CAS No. 93960-21-5. Molecular formula: C8H12Cl2N2O2. Mole weight: 239.10. | |
| H-D-Abu-OtBu | H-D-Abu-OtBu. Synonyms: (R)-tert-Butyl 2-Aminobutanoate; (2R)-2-aminobutyric acid tert-butyl ester; D-2-Aminobutyric acid tert-butyl ester; 2-Methyl-2-propanyl (2R)-2-aminobutanoate; Butanoic acid, 2-amino-, 1,1-dimethylethyl ester, (2R)-; D-α-Aminobutyric acid t-butyl ester. Grade: 95%. CAS No. 313994-32-0. Molecular formula: C8H17NO2. Mole weight: 159.23. | |
| HDAC10 FLAG tag active human | recombinant, expressed in baculovirus infected Sf9 cells, ?38% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| HDAC-10 human | recombinant, expressed in baculovirus infected insect cells, ?10% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-11 human | recombinant, expressed in baculovirus infected insect cells, ?10% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC1/2-IN-3 | HDAC1/2-IN-3 is an inhibitor of HDAC1 and HDAC2 with IC50s of 0-5 and 5-10 nM, respectively. Synonyms: N-(2-amino-5-(thiophen-2-yl)phenyl)-7-((2-(dimethylamino)ethyl)amino)-3-isoquinolinecarboxamide. CAS No. 2121516-17-2. Molecular formula: C24H25N5OS. Mole weight: 431.55. | |
| HDAC1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC 1 from Plasmodium falciparum | recombinant, expressed in baculovirus infected insect cells, ?40% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-1 human | recombinant, expressed in baculovirus infected insect cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC2, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC2 FLAG tag human | recombinant, expressed in baculovirus infected insect cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC 2 His tag human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC2-IN-2 | HDAC2-IN-2 (compound 124) is an inhibitor of HDAC2 with Kd value of 0.1-1 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 332169-78-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164050. |  |
| HDAC3 human | recombinant, expressed in insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC3 Inhibitor | HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM, IC50s = 0.95 nM). HDAC3 inhibitors increase histone acetylation and restore normal transcriptional patterns. Treatment with inhibitors primarily targeting HDAC3, including some with additional activity on HDAC1, led to improvement in motor function and working memory in N-terminal transgenic HD mice. Synonyms: Histone Deacetylase 3 Inhibitor; (E)-3-Phenyl-N-[[4-(propylaminocarbamoyl)phenyl]methyl]prop-2-enamide. Grade: ≥98%. CAS No. 2044701-99-5. Molecular formula: C20H23N3O2. Mole weight: 337.4. | |
| HDAC-3/NCOR2 human | recombinant, expressed in baculovirus infected insect cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-4 human | recombinant, expressed in baculovirus infected insect cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC5, active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-5 full length human | recombinant, expressed in baculovirus infected insect cells, ?10% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-5 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6 degrader-1 | HDAC6 degrader-1 (Compound NP8) is the PROTAC degrader for HDAC6 with a DC50 of 3.8 nM in cell MM.1S[1].(Blue: ligand for E3 ligase Pomalidomide (HY-10984); Black: linker (HY-140213); Pink: ligand for target protein Nexturastat A (HY-16699)). Uses: Scientific research. Group: Signaling pathways. CAS No. 2439058-23-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-132998. | |
| HDAC6 FLAG tag active human | recombinant, expressed in baculovirus infected Sf9 cells, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6 H216A human | recombinant, expressed in baculovirus infected Sf9 cells, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6 H611A human | recombinant, expressed in baculovirus infected Sf9 cells, ?79% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-6 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC6-IN-23 | HDAC6-IN-23 (compound 9) is an orally active HDAC6 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2991427-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-156274. | |
| HDAC6-IN-26 | HDAC6-IN-26 (compound 23) is a potent inhibitor of HDAC6 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2991427-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157219. | |
| HDAC6-IN-3 | HDAC6-IN-3 is an antiprostate cancer drug that is an effective MAO-A (IC50 = 0.79 μM) and LSD1 inhibitor, and a potent and orally active HDAC6 inhibitor with IC50s ranging from 0.02 to 1.54 μM for HDAC1/2/3/6/8/10. Synonyms: N1-hydroxy-N8-(3-((methyl(prop-2-yn-1-yl)amino)methyl)phenyl)octanediamide. Molecular formula: C19H27N3O3. Mole weight: 345.44. | |
| HDAC7, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-7 human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-8 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC8-IN-1 | HDAC8-IN-1 is a HDAC8 inhibitor with IC50 of 27.2 nM in cancer cell lines. Synonyms: (E)-N-hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide; VC-7933. Grade: 98% by HPLC. CAS No. 1417997-93-3. Molecular formula: C22H19NO3. Mole weight: 345.4. | |
| HDAC9, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-9 human | recombinant, expressed in baculovirus infected insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC/BET-IN-1 | HDAC/BET-IN-1 shows submicromolar inhibitory activity against HDAC1 and 6 (IC50s = 0.163 μM and 0.067 μM), and BRD4 (Ki = 0.076 μM). It has potent antileukemia activity. Synonyms: N-(2-((8-(hydroxyamino)-8-oxooctyl)oxy)-5-(morpholinosulfonyl)phenyl)-3-methyl-4-oxo-2,4,5,6,7,8-hexahydrocyclohepta[c]pyrrole-1-carboxamide. Molecular formula: C29H40N4O8S. Mole weight: 604.71. | |
| HDAC Class 2a Substrate 2, fluorogenic | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC Class 2a Substrate, fluorogenic | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| HDAC-IN-1 | HDAC-IN-1, an analogue of MC 1568, is a Iia HDACs inhibitor that could probably influence myogenesis and adipogenesis. Uses: Hdac-in-1 is a iia hdacs inhibitor that could probably influence myogenesis and adipogenesis. Synonyms: MC1568; MC 1568; MC-1568; HDAC-IN-1; HDAC IN 1. Grade: 98%. CAS No. 1239610-44-6. Molecular formula: C17H15FN2O3. Mole weight: 314.31. | |
| HDAC-IN-2 | HDAC-IN-2, a selective HDAC inhibitor, has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.It is under Phase II trials against Multiple myeloma. IC50: 4 nM and 76 nM for. Uses: Hdac-in-2 is a selective hdac inhibitor that has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.it is under phase ii trials against multiple myeloma. Synonyms: ACY-241; ACY 241; ACY241; HDAC-IN-2; Citarinostat; 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide; UNII-441P620G3P; 441P620G3P; Citarinostat. Grade: 98%. CAS No. 1316215-12-9. Molecular formula: C24H26ClN5O3. Mole weight: 467.95. | |
| HDAC-IN-26 | HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC50 of 4.7 nM. Synonyms: (S)-N-(1-(5-(2-fluorophenyl)-1H-imidazol-2-yl)-7-(isoxazol-3-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide; N-[(1S)-1-[5-(2-fluorophenyl)-1H-imidazol-2-yl]-7-isoxazol-3-yl-7-oxo-heptyl]-1-methyl-azetidine-3-carboxamide. CAS No. 2410542-97-9. Molecular formula: C24H28FN5O3. Mole weight: 453.51. | |
| HDAC-IN-28 | HDAC-IN-28 is an inhibitor of HDAC that has potent activity against tumor growth and metastasis. Synonyms: N-(4-Methoxyphenyl)-N-[[5-(5-pyrimidinyl)-2-thienyl]methyl]-7-(hydroxyamino)-7-oxoheptanamide. CAS No. 1621154-88-8. Molecular formula: C23H26N4O4S. Mole weight: 454.54. | |
| HDAC-IN-32 | HDAC-IN-32 is a potent inhibitor of HDAC with IC50s of 5.2, 11 and 28 nM for HDAC1, HDAC2 and HDAC6, respectively. HDAC-IN-32 has potent antiproliferation activities against tumor cells. It exhibits strong antitumor efficacy in vivo, and induces anti-tumor immunity. Synonyms: 7-(3-(1H-benzo[d]imidazol-2-yl)phenoxy)-N-hydroxyheptanamide. Molecular formula: C20H23N3O3. Mole weight: 353.41. | |
| HDAC-IN-33 | HDAC-IN-33 is a potent inhibitor of HDAC with IC50s of 24, 46 and 47 nM for HDAC1, HDAC2 and HDAC6, respectively. HDAC-IN-33 has potent antiproliferation activities against tumor cells. It exhibits strong antitumor efficacy in vivo, and induces anti-tumor immunity. Synonyms: 8-(3-(1H-benzo[d]imidazol-2-yl)phenoxy)-N-hydroxyoctanamide. Molecular formula: C21H25N3O3. Mole weight: 367.44. | |
| HDAC-IN-4 | HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1252003-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128763. | |
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