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It is produced from heparin by digestion with heparinase I and II. Synonyms: Alpha-delta-ua-2s-[1->4]-glcns sodium salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)tetrahydro-2H-pyran-3-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate; Trisodium 2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfonatoamino)-D-glucopyranose. Grades: ≥95%. CAS No. 136098-03-8. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide II-S trisodium salt
It is produced from heparinase II digestion of heparin and heparin sulphate. Synonyms: 2-Deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(Hydrogen sulfate) Trisodium Salt; Alpha-delta-ua-[1->4]-glcns-6S sodium salt; Trisodium 2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-2-(sulfonatoamino)-D-glucopyranose. CAS No. 136098-05-0. Molecular formula: C12H16NNa3O16S2. Mole weight: 563.35.
Heparin disaccharide I-P trisodium salt
It is prepared from heparin unsaturated disaccharide I-H by n-propionylation. It is a homologue of disaccharide I-A with the inclusion of a methylene group in the amide acyl group. It does not occur in nature and was devised as an internal standard for HPLC, CZE and CE analysis of heparin/heparin sulfate. It is also ideally suited as an internal standard for HLPC/CZE analysis of chondroitin series, after digestion with chondroitinases. Synonyms: Heparin unsaturated disaccharide I-P trisodium salt; (α-δUA-2S-[1?4]-GlcNCOEt-6S); 2-Deoxy-3-O-[(1R)-4-deoxyhex-4-enopyranuronosyl]-2-(propionylamino)-D-glycero-hexopyranose trisodium salt. Grades: 95%. CAS No. 149368-05-8. Molecular formula: C15H20NNa3O17S2. Mole weight: 619.42.
Heparin disaccharide I-S, tetrasodium salt
It is a predominant disaccharide produced from heparin by heparinase I and II. Synonyms: 2-Deoxy-4-O-(4-deoxy-2-O-sulfo-α-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose 6-(hydrogen sulfate) Sodium Salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)tetrahydro-2H-pyran-3-yloxy)-4-hydroxy-3-(sulfonatooxy)-3,4-dihydro-2H-pyran-6-carboxylate; alpha-DeltaUA-2S-[1->4]-GlcNS-6S; Tetrasodium 2-deoxy-4-O-(4-deoxy-2-O-sulfonato-α-L-threo-hex-4-enopyranuronosyl)-6-O-sulfonato-2-(sulfonatoamino)-D-glucopyranose. Grades: ≥98%. CAS No. 136098-10-7. Molecular formula: C12H15NNa4O19S3. Mole weight: 665.40.
Heparin disaccharide IV-A, sodium salt
It is produced from heparin sulfate by digestion with heparinase III. Synonyms: ΔGlcAΔ(1-4)GlcNAc; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; D-Glucopyranose, 2-(acetylamino)-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-, sodium salt (1:1); α-δ-UA-[1->4]-GLCNAC. Grades: ≥90%. CAS No. 136098-07-2. Molecular formula: C14H20NNaO11. Mole weight: 401.30.
Heparin disaccharide IV-H
It is the product of digestion of heparin sulfate and heparin by various heparinases. Synonyms: alpha-delta-UA-[1->4]-GLCN; 2-Amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-D-glucose; D-Glucose, 2-amino-2-deoxy-4-O-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-. Grades: 95%. CAS No. 123228-39-7. Molecular formula: C12H19NO10. Mole weight: 337.28.
Heparin disaccharide IV-S disodium salt
It is produced from heparin sulfate by digestion with heparinase III. Synonyms: Heparin unsaturated disaccharide IV-S, disodium salt; sodium (2R,3R,4S)-2-((2R,3S,4R,5R)-4,6-dihydroxy-2-(hydroxymethyl)-5-(sulfonatoamino)tetrahydro-2H-pyran-3-yloxy)-3,4-dihydroxy-3,4-dihydro-2H-pyran-6-carboxylate; 2-Deoxy-4-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucose disodium salt. Grades: ≥90%. CAS No. 136098-08-3. Molecular formula: C12H17NNa2O13S. Mole weight: 461.31.
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: N/A. CAS No. 9045-22-1. Prepack ID 36120358-1g. See USA prepack pricing.
Heparin Lithium salt
Heparin Lithium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII). Heparin Lithium salt significantly inhibits exosome-cell interactions. Uses: Scientific research. Group: Signaling pathways. CAS No. 9045-22-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17567B.
Heparin lithium salt from porcine intestinal mucosa
Heparin, Lithium salt USP. Grades: USP. CAS No. 9045-22-1. Product ID: 8-04702. Purity: Heparin assay ≥150 units/mg.
heparin lyase
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. Group: Enzymes. Synonyms: heparin eliminase; heparinase. Enzyme Commission Number: EC 4.2.2.7. CAS No. 9025-39-2. Heparinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5106; heparin lyase; EC 4.2.2.7; 9025-39-2; heparin eliminase; heparinase. Cat No: EXWM-5106.
Heparin lyase from Bacteroides thetaiotaomicron, Recombinant
Heparin lyase is an enzyme from Bacteroides thetaiotaomicron that acts on polysaccharides containing glucuronate or iduronate residues and 1,4-α linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues. Group: Enzymes. Synonyms: Heparin eliminase; Heparinase; EC 4.2.2.7. Enzyme Commission Number: EC 4.2.2.7. CAS No. 9025-39-2. Purity: >90% as judged by SDS-PAGE. Heparinase. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacteroides thetaiotaomicron. Heparin eliminase; Heparinase; EC 4.2.2.7. Cat No: NATE-1549.
Heparinoids. CAS No. 54328-33-5. Product ID: 4-00685. Properties: potential therapeutic for Alzheimer's Disease, Osteoporosis and high cholesterol and blood pressure.
Heparin polyaldehyde
Heparin 2,3-dialdehyde. Product ID: 5-02132. Purity: ~0.1 m mol aldehyde per gram of heparin.
Heparin Sodium
. CAS No. 9041-8-1. Product ID: 4-00057. Mole weight: Av. Mw ~15,000. Purity: Heparin assay~160 units/mg. Source : from porcine intestinal mucosa. Reference: J. Am. Med. Assn., 266, 382, 1991.
Heparin Sodium
Heparin sodium is an anticoagulant, is a kind of mucosaccharide, is extracted from the intestinal mucosa of pigs, cattle, sheep sodium salt glucosamine sulfate, in the human body is secreted by mast cells and naturally exists in the blood. Heparin sodium Chemicalbook can prevent platelet aggregation and destruction, inhibit the transformation of fibrinogen into fibrin monomer, inhibit the formation of thrombin and counter the already formed thrombin, prevent the transformation of prothrombin into thrombin and antithrombin. Synonyms: SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM;HEP, NA, BOVINE;HEP, NA, PORCINE;HEPARIN PORCINE SODIUM SALT. CAS No. 9041-8-1. Product ID: PAP-0071. Molecular formula: (C12H16NS2Na3)20. Category: Cardiovascular. Product Keywords: Cardiovascular Series; Heparin Sodium; PAP-0071; Cardiovascular; (C12H16NS2Na3)20; 9041-08-1. Standard: CP. Chemical Name: SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM;HEP, NA, BOVINE;HEP, NA, PORCINE;HEPARIN PORCINE SODIUM SALT. Grade: Pharmaceutical Grade. Solubility: H2O: 50 mg/mL, clear, faintly yellow. Storage: 2-8°C. Melting Point: >181°C (dec.). Product Description: Heparin sodium is an anticoagulant, is a kind of mucosaccharide, is extracted from the intestinal mucosa of pigs, cattle, sheep sodium salt glucosamine sulfate, in the human body is secreted by ma
Heparin Sodium
Heparin sodium is a sodium salt of heparin which is a naturally-occurring anticoagulant used for anticoagulation for cardiovascular disease. It is an inhibitor of activated coagulation factors such as Factors Xa and IIa (thrombin). Uses: Anticoagulation for cardiovascular disease. Synonyms: Adomiparin Sodium; Alfa 87-120; Ardeparin Sodium; Badyket; Bemiparin Sodium; Dalteparin Sodium; Deligoparin Sodium; Depo-Heparin; Fragmin; Hepaflush; Hepagumin; Hepalean; Heprinar; Hepsal; Lipo-Hepin; Liquaemin Sodium; Logiparin; Longheparin; Minolteparin Sodium; Monoparin; Nadroparine Sodium; Normiflo; Panheprin; Parnaparin Sodium; Pularin; Reviparin Sodium; Semuloparin Sodium; Sevuparin Sodium; Sodium Acid Heparin; Sodium Heparin; Sodium Heparinate; Thrombo-Hepin. CAS No. 9041-8-1. Molecular formula: (C12H16NS2Na3)20. Mole weight: 6000-20000.
Heparin sodium for assays
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Heparin sodium identification
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Heparin sodium LMW. CAS No. 9041-8-1. Product ID: 4-00058. Mole weight: Av. Mw ~5,000. Purity: Anti-Xa activity 100-120 units/mg. Properties: 50% suspension in PBS buffer, pH 6.5-7.550%. Source : Reference: Merck Index 11, 4898.
Heparin sodium LMW
Heparin sodium LMW. Grades: partially hydrolyzed contains terminal aldehyde. CAS No. 9041-8-1. Product ID: 4-00521. Mole weight: Av. Mw ~5,000 Da.
Heparin Sodium Molecular Weight Calibrant
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Heparin sodium salt
Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sodium heparin; Sodium heparinate. CAS No. 9041-8-1. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-17567A.
Heparin sodium salt from porcine intestinal mucosa
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals. CAS No. 9041-8-1. Prepack ID 27109831-1g. See USA prepack pricing.
Heparin sodium salt from porcine intestinal mucosa
5g Pack Size. Group: Bioactive Small Molecules, Biochemicals. CAS No. 9041-8-1. Prepack ID 27109831-5g. See USA prepack pricing.
Heparin sodium salt (Low in Ca)
Heparin sodium salt (Low in Ca) is a bioactive compound with potent anticoagulant properties that are essential in managing various blood clotting disorders, including deep vein thrombosis and pulmonary embolisms. Its unique mechanism of action involves the inhibition of blood clot formation, effectively reducing the risk of further complications. This specialized Heparin sodium salt formulation contains reduced levels of calcium, thus minimizing the potential incidence of the dreaded heparin-induced thrombocytopenia (HIT) syndrome. Complex yet highly effective, this anticoagulant therapy represents a crucial medical breakthrough in ensuring patient safety and well-being.
Heparin sodium salt (MW 15kDa)
Heparin sodium salt (MW 15kDa) (Sodium heparin (MW 15kDa)) is a polymer of Heparin with the molecular weight of 15kDa. Heparin sodium salt is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sodium heparin (MW 15kDa); Sodium heparinate (MW 15kDa). CAS No. 9041-8-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17567C.
Heparin Sodium System Suitability
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Heparin Sodium with Oversulfated Chondroitin Sulfate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
heparin-sulfate lyase
Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages. Group: Enzymes. Synonyms: heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II. Enzyme Commission Number: EC 4.2.2.8. CAS No. 37290-86-1. Heparinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5107; heparin-sulfate lyase; EC 4.2.2.8; 37290-86-1; heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II. Cat No: EXWM-5107.
Heparin-sulfate lyase from Bacteroides thetaiotaomicron, Recombinant
Heparin-sulfate lyase is an enzyme from Bacteroides thetaiotaomicron that acts on linkages between acetyl-glucosamine and uronate. Group: Enzymes. Synonyms: heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II; EC 4.2.2.8. Enzyme Commission Number: EC 4.2.2.8. CAS No. 37290-86-1. Purity: >90% as judged by SDS-PAGE. Heparinase. Mole weight: 76.7 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacteroides thetaiotaomicron. heparin-sulfate eliminase; heparitin-sulfate lyase; heparitinase I; heparitinase II; EC 4.2.2.8. Cat No: NATE-1550.
reducing terminal modified. suitable for conjugation to amine-containing biomolecules or resins. Product ID: 5-02813. Properties: UV (water): lmax 278.0 nm (e 8.5 x 103) for further conjugation of aldehyde- or ketone-containing biomolecules. Reference: Bioconjugate Chem., 6, 319, 1995.
Heparitin sulfate lyase
Heparitin sulfate lyase (Heparinase III) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Heparinase III. CAS No. 37290-86-1. Pack Sizes: 5 U; 10 U. Product ID: HY-P2953.
Heparosan from E. coli K5
Heparosan is an endogenous Glycosaminoglycan biosynthesized and secreted by E. coli K5. Heparosan serves as the starting carbon backbone for the chemoenzymatic synthesis of heparin, a widely used clinical anticoagulant drug. Synonyms: Heparosan; Heparosan (E. coli K5).
heparosan-glucuronate 5-epimerase
The enzyme, characterized from the giant African snail Achatina fulica, participates in the biosynthetic pathway of acharan sulfate. Unlike EC 5.1.3.17, heparosan-N-sulfate-glucuronate 5-epimerase, it shows no activity with D-glucuronate residues in heparosan-N-sulfate. Group: Enzymes. Synonyms: HG-5epi. Enzyme Commission Number: EC 5.1.3.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5423; heparosan-glucuronate 5-epimerase; EC 5.1.3.36; HG-5epi. Cat No: EXWM-5423.
heparosan-N-sulfate-glucuronate 5-epimerase
The enzyme acts on D-glucosyluronate residues in N-sulfated heparosan polymers, converting them to L-iduronate, thus modifying the polymer to heparan-N-sulfate. The enzyme requires that at least the N-acetylglucosamine residue linked to C-4 of the substrate has been deacetylated and N-sulfated, and activity is highest with fully N-sulfated substrate. It does not act on glucuronate residues that are O-sulfated or are adjacent to N-acetylglucosamine residues that are O-sulfated at the 6 position. Thus the epimerization from D-glucuronate to L-iduronate occurs after N-sulfation of glucosamine residues but before O-sulfation. Not identical with EC 5.1.3.19 chondroitin-glucuronate 5-epimerase or with EC 5.1.3.36, heparosan-glucuronate 5-epimerase. Group: Enzymes. Synonyms: heparosan epimerase; heparosan-N-sulfate-D-gl. Enzyme Commission Number: EC 5.1.3.17. CAS No. 112567-86-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5402; heparosan-N-sulfate-glucuronate 5-epimerase; EC 5.1.3.17; 112567-86-9; heparosan epimerase; heparosan-N-sulfate-D-glucuronosyl 5-epimerase; C-5 uronosyl epimerase; polyglucuronate epimerase; D-glucuronyl C-5 epimerase; poly[(1,4)-β-D-glucuronosyl-(1,4)-N-sulfo-α-D-glucosaminyl] glucurono-5-epimerase. Cat No: EXWM-5402.
Heparosan synthase from Pasteurella multocida, Recombinant
Heparosan synthase [pmHS enzyme] catalyzes transfer of GlcUA and GlcNAc to heparosan chain. Group: Enzymes. Synonyms: pmHS enzyme; PmHS2; Heparosan synthase 2. Enzyme Commission Number: EC 2.4.1.-. Purity: min 95% by SDS-PAGE. Heparosan synthase. Source: E. coli. Species: Pasteurella multocida. pmHS enzyme; PmHS2; Heparosan synthase 2; Heparosan synthase. Cat No: NATE-1487.
A cell-permeable imidazopyridinamine compound that selectively and potently induces differentiation of mesenchymal stem cells (MSCs) into hepatocyte-like cells (~47% at 5uM). Within 14 days of treatment with SJA710-6, the differentiated cells exhibit typical morphological characteristics of hepatocytes and are able to store glycogen, secret albumin, produce urea, and uptake LDL. Also, shown to increase the mRNA levels of hepatocyte-specific genes, such as albumin, AFP, CK18, c-Met, CYP1A1, CYP2B1, HNF3beta and FoxH1. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??BrFN?. US Biological Life Sciences.
Worldwide
Hepatitis C virus core antigen
~1 mg/mL, ?95% (SDS-PAGE), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Hepatitis C virus core antigen?Fluorescein
~1 mg/mL, ?95% (SDS-PAGE), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Hepatitis C virus core antigen?Rhodamine
~1 mg/mL, ?95% (SDS-PAGE), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Hepatitis C virus NS3 antigen 22kDa
0.5-1.4 mg/mL, ?90% (SDS-PAGE), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Hepatitis C virus NS4 antigen
~1 mg/mL, ?95% (SDS-PAGE), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Hepatitis C virus NS4 antigen?Biotin
~1 mg/mL, ?95% (SDS-PAGE), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Hepatitis C virus NS4 antigen?Fluorescein
~1 mg/mL, ?95% (SDS-PAGE), recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Hepatitis C virus NS4 antigen?Rhodamine
~1 mg/mL, ?95% (SDS-PAGE), recombinant, expressed in E. coli, solution. Group: Fluorescence/luminescence spectroscopy.
Hepatocyte Growth Factor human
HGF, recombinant, expressed in NSO cells, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Hepatocyte Growth Factor human
HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Hepatocyte Growth Factor Receptor (c-Met)/Fc Chimera human
HEPBS is a zwitterionic buffering agent with a pH range (7.6-9.0) similar to that of biological systems. HEPBS can be used in the culture of cells [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 161308-36-7. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W105704.
Hepcidin
Hepcidin, a liver-derived peptide hormone, is a key regulator of systemic iron homeostasis, and its unbalanced production contributes to the pathogenesis of a spectrum of iron disorders. Hepcidin has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. It is active against the fungus C. albicans. Synonyms: Liver-expressed antimicrobial peptide 1.
Hepcidin-1
Hepcidin-1 is isolated from Salmo salar. Hepcidin-1 seems to act as a signaling molecule involved in the maintenance of iron homeostasis. It seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. Hepcidin-1 may also have antimicrobial activity.
Hepcidin-1 (mouse)
Two kinds of hepcidin are found in mice. Hepcidin-1, a homolog of human Hepcidin-25 in serum, may be involved in murine brain iron metabolism. Hepcidin-2 is a pentapeptide with different sequences in urine. Synonyms: H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys22, Cys11-Cys19, Cys13-Cys14); L-alpha-aspartyl-L-threonyl-L-asparagyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-asparagyl-L-seryl-L-glutaminyl-L-cysteinyl-glycyl-L-isoleucyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->22),(11->19),(13->14)-tetrakis(disulfide); L-α-Aspartyl-L-threonyl-L-asparaginyl-L-phenylalanyl-L-prolyl-N-[(1R, 4R, 7S, 10S, 13R, 18R, 21R, 24S, 30R, 33S, 36S, 39S, 42S, 45R, 50R, 53S)-53-(4-aminobutyl)-18-{[(2S)-6-amino-1-{[(1S, 2R)-1-carboxy-2-hydroxypropyl]amino}-1-oxo-2-hexanyl]carbamoyl}-39, 42-bis(2-amino-2-oxoethyl)-33-(3-amino-3-oxopropyl)-7-benzyl-10, 24-di[(2S)-2-butanyl]-36-(hydroxymethyl)-3, 6, 9, 12, 20, 23, 26, 29, 32, 35, 38, 41, 44, 52, 55, 60-hexadecaoxo-15, 16, 47, 48, 57, 58, 63, 64-octathia-2, 5, 8, 11, 19, 22, 25, 28, 31, 34, 37, 40, 43, 51, 54, 61-hexadecaazatetracyclo[28.25.4.44, 21.245, 50]pentahexacont-13-yl]-L-isoleucinamide. Grades: ≥95%. CAS No. 1676104-75-8. Molecular formula: C111H169N31O35S8. Mole weight: 2754.28.
Hepcidin-1 (mouse) TFA
Hepcidin-1 (mouse) TFA is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) TFA upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) TFA downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) TFA facilitates osteoclast differentiation[1]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4373A.
Hepcidin-2
Hepcidin-2 is isolated from Mus musculus. It seems to act as a signaling molecule involved in the maintenance of iron homeostasis.
Hepcidin-22 (human)
Hepcidin-22 (human) is an inactive degradation product of Hepcidin-25 found in human urine. Synonyms: H-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys4-Cys10, Cys7-Cys20, Cys8-Cys19, Cys11-Cys16, air oxidized); L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-glycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinyl-glycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (4->10),(7->20),(8->19),(11->16)-tetrakis(disulfide). Grades: ≥95%. CAS No. 342790-22-1. Molecular formula: C99H151N29O25S9. Mole weight: 2436.06.
Hepcidin-24 (human)
Hepcidin-24, an excellent substitute for biotinylated or heavy isotope-labeled hepcidin-25, is used as an internal reference in the determination of Hep-25 by mass spectrometry-based methods, for example in human serum or urine. Synonyms: H-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys6-Cys22, Cys9-Cys12, Cys10-Cys18, Cys13-Cys21, air oxidized); des-Asp1-Hepcidin-24. Grades: ≥95%. Molecular formula: C109H165N33O28S9. Mole weight: 2674.31.
Hepcidin-25 (human)
Hepcidin-25 (hepatic bactericidal protein), also known as LEAP-1 (liver-expressed antimicrobial peptide), is found independently in human blood ultrafiltration and urine. It is mainly expressed in liver and belongs to a new family of small vertebrate antimicrobial peptides that contain 8 cysteine residues and has obvious antibacterial and antifungal activities. Hepcidin is the main human iron regulatory hormone, which can bind to iron exporter ferroportin and induce its internalization and degradation, thus blocking iron efflux from cells. Uses: Anti-infective agents. Synonyms: LEAP-1 (human); H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, Cys14-Cys22); L-alpha-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-glycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinyl-glycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->13),(11->19),(14->22)-tetrakis(disulfide); Hepcidin Hepc25 (human); Hepcidin-25. Grades: ≥95% by HPLC. CAS No. 1356390-47-0. Molecular formula: C113H170N34O31S9. Mole weight: 2789.35.