A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Iron Trisglycinate is used in biological studies to evaluate the dietary iron absorption from whole corn meal in humans. Group: Biochemicals. Alternative Names: Ferric Glycinate, Iron Glycinate, Tris (glycinato)iron (III). Grades: Highly Purified. CAS No. 34369-82-9. Pack Sizes: 25mg, 100mg, 500mg. Molecular Formula: C6H12FeN3O6. US Biological Life Sciences.
IRON ZIRCONATE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IRON ZIRCONATE;diiron zirconium pentaoxide. Product Category: Heterocyclic Organic Compound. CAS No. 52933-62-7. Molecular formula: Fe2O5Zr. Mole weight: 282.91. Product ID: ACM52933627. Alfa Chemistry ISO 9001:2015 Certified.
Irosustat
Irosustat is a potent steroid sulfatase inhibitor, with an IC 50 of 8 nM, and exhibits anti-breast cancer activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STX64; BN83495; 667-Coumate. CAS No. 288628-05-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14586.
Irosustat
Irosustat, also known as STX64, BN83495 and 667 coumate, is a potent, irreversible inhibitor of steroid sulfatase. Inhibition of steroid sulfatase (STS), the enzyme responsible for the hydrolysis of steroid sulfates, represents a potential novel treatment for postmenopausal women with hormone-dependent breast cancer. Estrone and DHEA are formed by this sulfatase pathway and can be converted to steroids (estradiol and androstenediol, respectively), which have potent estrogenic properties. STX64 (667 coumate) is a potent tricylic coumarin-based sulfamate that irreversibly inhibits STS activity (IC50= 8 nM in a placental microsomal assay system). Estrone sulfamate (EMATE) is also a potent STS inhibitor, but has estrogenic activity. Synonyms: BN83495; BN-83495; BN 83495; STX 64; STX-64; STX64; 667-Coumate; Sulfamic acid, 6,7,8,9,10,11-hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl ester. CAS No. 288628-05-7. Molecular formula: C14H15NO5S. Mole weight: 309.34.
Irpexan
Irpexan is originally isolated from Irpex sp. 93028. Synonyms: 10-Hydroxy-11-(beta-D-mannopyranosyloxy)-2,6,10,15,19,23-hexamethyl-2,6,14,18,22-tetracosapentaene. Molecular formula: C36H62O7. Mole weight: 606.87.
Ir[p-F(Me)ppy]2(dtbbpy)PF6
Ir[p-F(Me)ppy]2(dtbbpy)PF6 is a cyclometalated iridium(III) complex that can be used in visible-light mediated photocatalytic organic transformations. Uses: Transition metal catalysts. Synonyms: [Ir(p-F(Me)ppy)2-(4,4'-dtbbpy)]PF6; [4,4'-Bis(1,1-dimethylethyl)-2,2'-bipyridine-κN,κN]bis[5-fluoro-2-(5-methyl-2-pyridinyl-κN)phenyl-κC]iridium hexafluorophosphate; Iridium(1+), [4,4'-bis(1,1-dimethylethyl)-2,2'-bipyridine-κN1,κN1']bis[5-fluoro-2-(5-methyl-2-pyridinyl-κN)phenyl-κC]-, (OC-6-33)-, hexafluorophosphate(1-) (1:1); [(4,4'-di-tert-butyl-2,2'-bipyridine)-bis-(5-methyl-2-(5-fluoro-phenyl)-pyridine)-iridium(III)] hexafluorophosphate. Grades: ≥95%. CAS No. 808142-88-3. Molecular formula: C42H42F2IrN4.F6P. Mole weight: 977.99.
Ir(piq)2(acac)
Ir(piq)2(acac). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(1-phenylisoquinoline)(acetylacetonate)iridium(III). Product Category: Organic Light Emitting Diode (OLED). CAS No. 435294-03-4. Molecular formula: C35H27N2O2Ir. Mole weight: 699.82 g/mol. Product ID: ACM435294034. Alfa Chemistry ISO 9001:2015 Certified.
Ir(piq)3
Ir(piq)3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tris(1-phenylisoquinoline)iridium(III). Product Category: Organic Light Emitting Diode (OLED). CAS No. 435293-93-9. Molecular formula: C45H30N3Ir. Mole weight: 804.96 g/mol. Product ID: ACM435293939-6. Alfa Chemistry ISO 9001:2015 Certified.
Ir(ppy)2(acac). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(2-phenylpyridine)(acetylacetonate)iridium(III). Product Category: Organic Light Emitting Diode (OLED). CAS No. 337526-85-9. Molecular formula: C27H23IrN2O2. Mole weight: 599.70 g/mol. Product ID: ACM337526859-4. Alfa Chemistry ISO 9001:2015 Certified.
Ir(ppy)2(bpmp)
Ir(ppy)2(bpmp). Uses: Designed for use in research and industrial production. Additional or Alternative Names: [2-(4-Methyl-5-phenyl-2-pyridinyl-κN)phenyl-κC]bis[2-(2-pyridinyl-κN)phenyl-κC] Iridium. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1215692-34-4. Molecular formula: C40H30IrN3. Mole weight: 744.9 g/mol. Product ID: ACM1215692344. Alfa Chemistry ISO 9001:2015 Certified.
Ir(ppy)3-Bp
Ir(ppy)3-Bp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tris[3- (2- pyridinyl- kN) [1, 1':4', 1''- terphenyl] - 4- yl- kC] - iridium(III). Product Category: Organic Light Emitting Diode (OLED). CAS No. 1404192-47-7. Molecular formula: C69H48IrN3. Mole weight: 1111.36 g/mol. Product ID: ACM1404192477. Alfa Chemistry ISO 9001:2015 Certified.
Ir(ppz)3
Ir(ppz)3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tris(phenylpyrazole)iridium. Product Category: Organic Light Emitting Diode (OLED). CAS No. 562824-31-1. Molecular formula: C27H21N6Ir. Mole weight: 621.71 g/mol. Product ID: ACM562824311. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ir(ppy)3.
Irsenontrine (E2027) is an orally active and selective phosphodiesterase 9 ( PDE9 ) inhibitor. Irsenontrine can be used for the research of neurological diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E2027. CAS No. 1429509-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132821.
Irsenontrine
Irsenontrine is a phosphodiesterase (PDE) 9 inhibitor for the treatment of lewy body dementia and Parkinson's disease dementia. Synonyms: 7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-[(3S)-oxolan-3-yl]-1,5-dihydro-4H-pyrazolo[4,3-c]quinolin-4-one; (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one; 4H-Pyrazolo(4,3-c)quinolin-4-one, 1,5-dihydro-7-(2-methoxy-3,5-dimethyl-4-pyridinyl)-1-((3S)-tetrahydro-3-furanyl)-; WHO11606; WHO-11606; WHO 11606. Grades: >98%. CAS No. 1429509-82-9. Molecular formula: C22H22N4O3. Mole weight: 390.44.
Irsogladine
Irsogladine. Group: Biochemicals. Grades: Highly Purified. CAS No. 57381-26-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C9H7Cl2N5. US Biological Life Sciences.
Worldwide
Irsogladine
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.Irsogladine treatment (300 and 500 mg/kg/day) resulted in a dose-dependent reduction of angiogenesis in wild-type mice by 21 and 45.3% (P < 0.02, P < 0.001), in tPA-deficient mice by 42.6 and 46% (P < 0.001, P < 0.001), and in uPA-deficient mice by 27.2 and 46% (P < 0.05, p < 0.001), respectively. Uses: Anti-ulcer agents. Synonyms: Irsogladine; 57381-26-7; dicloguamine; 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine; Irsogladine [INN]; 1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-; QBX79NZC1D; 2,4-Diamino-6-(2,5-dichlorophenyl)-s-triazine;[4-amino-6-(2,5-dichlorophenyl)-s-triazin-2-yl]amine; maleic acid; (Z)-2-butenedioic acid; 6-(2,5-dichlorophenyl)-1,3,5-triazine-2,4-diamine; 6-[2,5-bis(chloranyl)phenyl]-1,3,5-triazine-2,4-diamine; (Z)-but-2-enedioic acid. Grades:>98%. CAS No. 57381-26-7. Molecular formula: C9H7Cl2N5. Mole weight: 256.09.
Irsogladine
100mg Pack Size. Group: Bioactive Small Molecules, Building Blocks, Organics, Research Organics & Inorganics. Formula: C9H7Cl2N5. CAS No. 57381-26-7. Prepack ID 80045416-100mg. Molecular Weight 256.09. See USA prepack pricing.
Irsogladine
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dicloguamine. CAS No. 57381-26-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0327.
An anti-ulcer drug. Group: Biochemicals. Alternative Names: 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine (2Z)-2-Butenedioate; 2,4-Diamino-6-(2,5-dichlorophenyl)-s-triazine maleate; Gaslon; Gaslon N. Grades: Highly Purified. CAS No. 84504-69-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Irsogladine Maleate
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. It inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout mice. It up-regulates GJIC between PC cells via regulation of the PKA pathway. It also suggests a useful adjuvant of Irsogladine to pancreatic cancer therapy. It also produces the increase of intracellular cAMP content via non-selective inhibition of PDE isozymes, which may be a key mechanism involved in its gastroprotective actions. Synonyms: Dicloguamine maleate; MN1695; MN 1695; MN-1695. Grades: >98%. CAS No. 84504-69-8. Molecular formula: C13H11Cl2N5O4. Mole weight: 372.16.
Ir(tfpd)2pic
Ir(tfpd)2pic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bis(3,4,5-trifluoro-2-(2-pyridyl)phenyl-(2-carboxypyridyl)iridium(III). Product Category: Organic Light Emitting Diode (OLED). CAS No. 1417790-60-3. Molecular formula: C28H14F6IrN3O2. Mole weight: 730.64 g/mol. Product ID: ACM1417790603. Alfa Chemistry ISO 9001:2015 Certified.
IRTK Activator III, DDN (5,8-Diacetyloxy-2,3-dichloro-1,4-naphthoquino)
An orally bioavilable diacetyloxy-naphthoquinone compound that directly targets insulin receptor tyrosine kinase (IRTK) domain and specifically increases IR kinase activity with no effect on IGF-1R and EGFR. Shown to rapidly phosphorylate IR (Tyr1146 and Tyr1158/1162/1163) and IRS-1 and selectively activate insulin signaling Akt (Thr473) and ERK pathways in CHO-IGF-IR cells at 5uM. Sensitizes insulin action, enhances glucose uptake in differentiated 3T3-L1 adipocytes and decreases blood glucose levels in both normal and diabetic C57BL/6J mice (20mg/kg, p.o.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Iruplinalkib
Iruplinalkib (WX-0593) is an orally active and selective ALK/ROS1 inhibitor. Iruplinalkib can effectively inhibit tyrosine autophosphorylation of ALK and mutant ALK , EGFR , with the IC 50 between 5.38 and 16.74 nM. Iruplinalkib is also a suppressive agent of the transporter MATE1 , MATE2K , P-gp and BCRP. Iruplinalkib can be used in the study of non-small cell lung cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WX-0593. CAS No. 1854943-32-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145574.
Irvingia Gabonensis P.E. 4:1
Irvingia Gabonensis P.E. 4:1.
CA, FL & NJ
ISA-2011B
ISA-2011B is a Phosphatidylinositol-4-phosphate 5-kinase-α (PIP5Kα) inhibitor. Research shows that the overexpression of PIP5K1α is associated with poor prognosis in prostate cancer and correlates with an elevated level of the androgen receptor. ISA-2011B can inhibit growth of tumor cells in xenograft mice, which is mediated by targeting PIP5K1α-associated PI3K/AKT and the downstream survival, proliferation, and invasion pathways. Uses: Anti-cancer. Synonyms: ISA2011B; ISA 2011B; ISA-2011B; ISA2011-B; ISA 2011-B; ISA-2011-B. (5S,10aS)-5-(5-chloro-1H-indol-3-yl)-9-methyl-8,9,10a,11-tetrahydro-5H-[1,3]dioxolo[4,5-g]pyrazino[1,2-b]isoquinoline-7,10-dione. Grades: 98%. CAS No. 1395347-24-6. Molecular formula: C22H18ClN3O4. Mole weight: 423.85.
ISA (ionic strength adjustment solution: 1 M KCl)
1 M KCl. Group: Ionic strength adjustor solutions (isa).
ISAM 140
ISAM 140 is a potent and highly selective A2B adenosine receptor antagonist (A2BAR) with Ki value of 3.49 nM. It shows high affinity for A2B over A1, A2A, and A3 adenosine receptors. Synonyms: ISAM-140; ISAM 140; ISAM140; 4-(2-Furanyl)-4,10-dihydro-2-methylpyrimido[1,2-a]benzimidazole-3-carboxylic acid-1-methylethyl ester; (±)-Isopropyl 4-(Furan-2-yl)-2-methyl-1,4-dihydrobenzo-[4,5]imidazo[1,2-a]pyrimidine-3-carboxylate. Grades: ≥98% by HPLC. CAS No. 932191-62-3. Molecular formula: C19H19N3O3. Mole weight: 337.37.
Isamoltane hemifumarate, an analog of isamoltane, is a beta-adrenoceptor ligand with approximately 30-fold selective over 5-HT1A. Synonyms: 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(1H-pyrrol-1-yl)phenoxy]-, (2E)-2-butenedioate (2:1); 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(1H-pyrrol-1-yl)phenoxy]-, (2E)-2-butenedioate (2:1) (salt); Isamoltane fumarate (2:1); 1-(2-(1H-pyrrol-1-yl)phenoxy)-3-(isopropylamino)propan-2-ol hemifumarate; 1-(Isopropylamino)-3-[2-(1H-pyrrol-1-yl)phenoxy]-2-propanol hemifumarate. Grades: ≥99% by HPLC. CAS No. 874882-92-5. Molecular formula: C16H22N2O2.1/2C4H4O4. Mole weight: 332.40.
Isamoltane hemifumarate
Isamoltane hemifumarate. Group: Biochemicals. Grades: Purified. CAS No. 874882-92-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ISAMP
ISAMP is an antibacterial peptide isolated from Ixodes scapularis. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Pro-Asp-Pro-Gly-Gln-Pro-Trp-Gln-Val-Lys-Ala-Gly-Arg-Pro-Pro-Cys-Tyr-Ser-Ile-Pro-Cys-Arg-Lys-His-Asp-Glu-Cys-Arg-Val-Gly-Ser-Cys-Ser-Arg-Cys-Asn-Asn-Gly-Leu-Trp-Gly-Asp-Arg-Thr-Cys-Arg.
I-SAP
I-SAP is a high affinity TP receptor antagonist. I-SAP binds to and induces platelet shape change, but not aggregation, with EC50 value of 9.7 nM. Synonyms: Iodophenyl sulfonyl amino pinane Thromboxane A2; Iodophenyl sulfonyl amino pinane TXA2; (Z)-7-[(1S,2S,3S,5R)-3-[(4-iodophenyl)sulfonylamino]-6,6-dimethyl-2-bicyclo[3.1.1]heptanyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 133538-58-6. Molecular formula: C22H30INO4S. Mole weight: 531.4.
Isariin
Isariin is originally isolated from Isaria felina. Synonyms: (R)-N-(N-(N-(N-(N-(3-hydroxy-1-oxododecyl)glycyl)-L-valyl)-D-leucyl)-L-alanyl)-L-Valine rho-lactone; Cyclo[L-alanyl-L-valyl-(3R)-3-hydroxydodecanoylglycyl-L-valyl-D-leucyl]. CAS No. 10409-85-5. Molecular formula: C33H59N5O7. Mole weight: 637.85.
Isariin A
Isariin A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10409-85-5. Molecular formula: C33H59N5O7. Mole weight: 637.44. Catalog: APB10409855.
Isariin B
Isariin B is originally isolated from Isaria felina. Synonyms: 19-hexyl-6-methyl-9-(2-methylpropyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone. CAS No. 80111-95-1. Molecular formula: C30H53N5O7. Mole weight: 595.77.
Isariin C
Isariin C is originally isolated from Isaria felina. It has insecticidal effect. Synonyms: 19-hexyl-3,6-dimethyl-9-(2-methylpropyl)-12-(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone. CAS No. 80111-96-2. Molecular formula: C28H49N5O7. Mole weight: 567.72.
Isariin D
Isariin D is originally isolated from Isaria felina. It has insecticidal effect. Synonyms: 19-butyl-3,6-dimethyl-9-(2-methylpropyl)-12-(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone. Grades: >98%. CAS No. 80111-97-3. Molecular formula: C26H45N5O7. Mole weight: 539.66.
Isatin
Isatin. CAS No. 91-56-5.
Pennsylvania PA
Isatin
500g Pack Size. Group: Building Blocks, Organics, Stains & Indicators. Formula: C8H5NO2. CAS No. 91-56-5. Prepack ID 18322362-500g. Molecular Weight 147.13. See USA prepack pricing.
Isatin
Isatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 91-56-5. Pack Sizes: 250g, 500g, 1Kg, 2Kg, 5kg. Molecular Formula: C8H5NO2. US Biological Life Sciences.
Worldwide
Isatin
Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC 50 of 3 μM. Also binds to central benzodiazepine receptors (IC 50 against clonazepam, 123 μM) [1]. Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity [2]. Shows effect on the serotonergic system [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Indoline-2,3-dione. CAS No. 91-56-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0265.
Isatin
Isatin is an indole derivative used as an intermediate. It also acts as an endogenous MAO inhibitor with an IC50 value of 15 μM. Synonyms: 1H-indole-2,3-dione. CAS No. 91-56-5. Molecular formula: C8H5NO2. Mole weight: 147.13.
Isatin-5-sulfonic Acid Monosodium Salt Monohydrate
Reagent used in the preparation of biologically active Isatin derivatives. Group: Biochemicals. Alternative Names: 5-Sulfoisatin Sodium Salt Monohydrate; 2,3-Dihydro-2,3-dioxo-1H-indole-5-sulfonic Acid Sodium Salt Hydrate. Grades: Highly Purified. CAS No. 303137-11-3. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Isatin-5-sulfonic acid sodium salt dihydrate
Isatin-5-sulfonic acid sodium salt dihydrate. Group: Biochemicals. Alternative Names: Sodium isatin-5-sulfonate dihydrate. Grades: Highly Purified. CAS No. 207399-16-4. Pack Sizes: 5g, 10g, 25g, 50g. Molecular Formula: C8H4NNaO5S·2H2O. US Biological Life Sciences.
Worldwide
Isatin 98+% (HPLC)
Isatin 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 1Kg, 5Kg, 10Kg. US Biological Life Sciences.
Worldwide
Isatin bis-cresol
Isatin bis-cresol. Group: Biochemicals. Alternative Names: 1,3-Dihydro-3,3-bis(4-hydroxy-3-methylphenyl)-2H-indol-2-one. Grades: Highly Purified. CAS No. 47465-97-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C22H19NO3. US Biological Life Sciences.
Worldwide
isatin hydrolase
Requires Mn2+. This enzyme, found in several bacterial species, is involved in the degradation of indole-3-acetic acid. Group: Enzymes. Enzyme Commission Number: EC 3.5.2.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4504; isatin hydrolase; EC 3.5.2.20. Cat No: EXWM-4504.
Isatoic anhydride
Isatoic anhydride is a molecule with a structure similar to trans-bis-isatoic anhydride (TBIA), but has only one reactive group. Isatoic anhydride forms monoadducts [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118-48-9. Pack Sizes: 10 mM * 1 mL; 50 g; 100 g; 250 g; 500 g. Product ID: HY-76222.
Isatoic Anhydride
Isatoic anhydride is a potent inactivator of α-chymotrypsin and inactivates stoichiometrically. Isatoic Anhydride is an important compound in the preparation of serine protease inhibitors. Group: Biochemicals. Alternative Names: 2H-3,1-Benzoxazine-2,4(1H)-dione; 1,2-Dihydro-3,1-benzoxazine-2,4-dione; 1H-Benz[d][1,3]oxazine-2,4-dione; 2,4-Dioxo-1,2-dihydro-4H-3,1-benzoxazine; 3,1-Benzoxazine-2,4(1H)-dione; 2-(Carboxyamino)benzoic Acid Cyclic Anhydride; Isatoic Acid Anhydride; NSC 104662; NSC 29555. Grades: Highly Purified. CAS No. 118-48-9. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Isatoribine
Isatoribine is a novel guanosine analogue showing immunostimulatory activity both in vivo and in vitro. This compound acts on different components of the immune system including B cells, natural killer (NK) cells and antigen-presenting cells (APC). Synonyms: ANA245; ANA 245; ANA-245; Immusine; Isatoribine hydrate; Isatoribine monohydrate; D04619; D 04619; D-04619; 7-thia-8-oxoguanosine. CAS No. 198832-38-1. Molecular formula: C10H14N4O7S. Mole weight: 334.30.
Isatropolone A
Antileishmanial agent. Active against Leishmania donovani, the causative agent of visceral leishmaniasis. Showed no activity against intracellular Leishmania. Isatropolone A is an. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Isatuximab
Isatuximab is an anti-CD38 monoclonal antibody that has been approved for use in the treatment of adults with multiple myeloma. Synonyms: SAR650984; hu38SB19. CAS No. 1461640-62-9.
Isatuximab
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38 , a protein highly expressed on hematological malignant cells, including those in multiple myeloma (MM). Isatuximab has antitumor activity via multiple biological mechanisms, including antibody-dependent cellular-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and direct induction of apoptosis without crosslinking. Isatuximab also directly inhibits CD38 ectoenzyme activity, which is implicated in many cellular functions [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1461640-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9976.
Isatuximab (anti-CD38)
Isatuximab (anti-CD38) is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38.Isatuximab induces tumor cell killing via fragment crystallizable (Fc)-dependent or Fc-independent mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1461640-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9976A.
Isavuconazole
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H17F2N5OS. CAS No. 241479-67-4. Prepack ID 90026880-25mg. Molecular Weight 437.46. See USA prepack pricing.
Isavuconazole
Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Isavuconazole;4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile;2R,3R)-3-[4-(4-Cyanophenyl)thiazol-2-yl]-2-(2,5-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;BAL 4815;RO 0094815;Isavuconazolep;4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-Methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile;NaMe:Isavuconazole;4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile. Product Category: Inhibitors. CAS No. 241479-67-4. Molecular formula: C22H17F2N5OS. Mole weight: 437.4650864. Purity: 0.9997. Density: 1.38. Product ID: ACM241479674. Alfa Chemistry ISO 9001:2015 Certified.
Isavuconazole
?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral moleculesimpurity standardspharmaceutical toxicology. Alternative Names: (2R,3R)-3-[4-(4-Cyanophenyl)thiazol-2-yl]-2-(2,5-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, 1-[(2R,3R)-3-[4-(4-Cyanophenyl)thiazol-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-1,2,4-triazole, 2R,3R)-3-[4-(4-Cyanophenyl)thiazol-2-yl]-2-(2,5-,4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile, 4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]-benzonitrile, RO 0094815, BAL 4815, Isavuconazole.
Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL-4815; RO-0094815. CAS No. 241479-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14273.
Isavuconazole
Isavuconazole is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp. Uses: Antifungal agents. Synonyms: BAL4815; BAL-4815; BAL 4815; RO 0094815; RO-0094815; RO0094815; Cresemba. Grades: >98%. CAS No. 241479-67-4. Molecular formula: C22H17F2N5OS. Mole weight: 437.47.
Isavuconazole-d4
Isavuconazole-d 4 is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BAL-4815-d4; RO-0094815-d4. CAS No. 1346598-58-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-14273S.