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leucovorin calcium is an active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonist-type chemotherapeutic drugs. Leucovorin calcium counteracts the toxic effects of these medications, 'rescuing' the patient while permitting the antitumor activity of the folate antagonist. This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity. Synonyms: IST5-002; IST5 002; IST5002; Benzyl-AMP; N6-Benzyladenosine-5'-phosphate; Folinic acid calcium salt; Calcium Folinate. Grades: >98%. CAS No. 1492-18-8. Molecular formula: C20H21N7O7.Ca. Mole weight: 513.52.
Leucovorin calcium pentahydrate
Leucovorin is a derivative of folic acid, which can be used to increase levels of folic acid under conditions favoring folic acid inhibition. Synonyms: Folinic acid. Grades: >98%. CAS No. 6035-45-6. Molecular formula: C21H25CaN7O7.5H2O. Mole weight: 601.58.
An intermediate product of the metabolism of Folic Acid; the active form into which that acid is converted in the body, ascorbic acid being a necessary factor in the conversion process. Group: Biochemicals. Alternative Names: N-[4-[[ (2-Amino-5-formyl-1, 4, 5, 6, 7, 8-hexahydro-4-oxo-6-pteridinyl) methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt Pentahydrate; Calcium Folinate; Folaren; Foliben; Folidan; Folinic Acid Calcium Salt Pentahydrate; Lederfolat; Lederfolin. Grades: Highly Purified. CAS No. 6035-45-6. Pack Sizes: 100mg, 500mg, 1g. Molecular Formula: C20H31CaN7O12, Molecular Weight: 601.58. US Biological Life Sciences.
Worldwide
Leucovorin-d4 Calcium Salt Pentahydrate
An labeled intermediate product of the metabolism of Folic Acid. This compound is a mixture of diastereomers. Group: Biochemicals. Alternative Names: N-[4-[[ (2-Amino-5-formyl-1, 4, 5, 6, 7, 8-hexahydro-4-oxo-6-pteridinyl) methyl]amino]benzoyl-d4]-L-glutamic Acid Calcium Salt Pentahydrate; Calcium Folinate-d4; Folaren-d4; Foliben-d4; Folidan-d4; Folinic Acid-d4 Calcium Salt Pentahydrate. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
leucyl aminopeptidase
A zinc enzyme isolated from pig kidney and cattle lens; activated by heavy metal ions. Type example of peptidase family M17. Group: Enzymes. Synonyms: leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I. Enzyme Commission Number: EC 3.4.11.1. CAS No. 9001-61-0. LAP. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4007; leucyl aminopeptidase; EC 3.4.11.1; 9001-61-0; leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase; leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II; aminopeptidase III; aminopeptidase I. Cat No: EXWM-4007.
Leucylarginylproline, also called as H-Leu-Arg-Pro-OH, is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.27μM). Synonyms: H-Leu-Arg-Pro-OH; L-leucyl-L-arginyl-L-proline; (2S)-1-[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-5 (diaminomethylideneamino) pentanoyl]pyrrolidine-2-carboxylic acid. CAS No. 133943-59-6. Molecular formula: C17H32N6O4. Mole weight: 384.47.
leucyl endopeptidase
From leaves of the spinach plant (Spinacia oleracea). Group: Enzymes. Synonyms: plant Leu-proteinase; leucine-specific serine proteinase; leucine endopeptidase; spinach serine proteinase (leucine specific); spinach leucine-specific serine proteinase; Leu-proteinase. Enzyme Commission Number: EC 3.4.21.57. CAS No. 136396-22-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4148; leucyl endopeptidase; EC 3.4.21.57; 136396-22-0; plant Leu-proteinase; leucine-specific serine proteinase; leucine endopeptidase; spinach serine proteinase (leucine specific); spinach leucine-specific serine proteinase; Leu-proteinase. Cat No: EXWM-4148.
Leucyl-lysine is a dipeptide composed of leucine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Lysine, L-Leucyl-; (S)-6-Amino-2-((S)-2-amino-4-methylpentanamido)hexanoic acid; L-leucyl-L-lysine; H-LK-OH; Leu-Lys; L-Leu-L-Lys. Grades: ≥95%. CAS No. 6416-76-8. Molecular formula: C12H25N3O3. Mole weight: 259.35.
Leucyl-phenylalanine
Leucyl-phenylalanine is a competitive inhibitor of both the peptidase and the esterase activities of carboxy peptidase Y. Synonyms: L-leucyl-L-Phenylalanine. CAS No. 3063-5-6. Molecular formula: C15H22N2O3. Mole weight: 278.35.
Leucyl-phenylalanine
Leucyl-phenylalanine belongs to the class of organic compounds known as dipeptides. Uses: Scientific research. Group: Natural products. CAS No. 3063-5-6. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-113278.
Leucyl-serine
Leucyl-serine is a dipeptide composed of leucine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-leucyl-L-serine; H-LS-OH; Leu-Ser; N-Leucylserine; L-Leu-L-Ser; Leu-Ser-OH; N-L-leucyl-L-serine; L-Serine, L-leucyl-. Grades: ≥95% by HPLC. CAS No. 6209-12-7. Molecular formula: C9H18N2O4. Mole weight: 218.25.
Also transfers phenylalanyl groups. Requires a univalent cation. Peptides and proteins containing an N-terminal arginine, lysine or histidine residue can act as acceptors. Group: Enzymes. Synonyms: leucyl, phenylalanine-tRNA-protein transferase; leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase; leucyl-phenylalanine-transfer ribonucleate-protein transferase; L-leucyl-tRNA:protein leucyltransferase. Enzyme Commission Number: EC 2.3.2.6. CAS No. 37257-22-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2306; leucyltransferase; EC 2.3.2.6; 37257-22-0; leucyl, phenylalanine-tRNA-protein transferase; leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase; leucyl-phenylalanine-transfer ribonucleate-protein transferase; L-leucyl-tRNA:protein leucyltransferase. Cat No: EXWM-2306.
Leu-D-Leu
Leu-D-Leu is a specific substrate for D-peptidase S, an intracellular carboxypeptidase-like enzyme that preferentially hydrolyzes dipeptides containing hydrophobic D-amino acids. Synonyms: l-Leucyl-d-leucine; D-Leucine, L-leucyl-; N-L-Leucyl-D-leucine; (R)-2-((S)-2-amino-4-methylpentanamido)-4-methylpentanoic acid. CAS No. 17665-02-0. Molecular formula: C12H24N2O3. Mole weight: 244.33.
Leu-enkephalin-lys
Leu-enkephalin-lys. Uses: Designed for use in research and industrial production. Additional or Alternative Names: LEU-ENKEPHALIN-LYS;LEU-ENKEPHALIN-LYS ACETATE SALT;H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACETATE SALT;H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACOH;H-Tyr-Gly-Gly-Phe-Leu-Lys-OH;leucine enkephalin-lys;leucine enkephalin lysine. Product Category: Heterocyclic Organic Compound. CAS No. 83404-43-7. Molecular formula: C34H49N7O8. Mole weight: 743.85. Product ID: ACM83404437. Alfa Chemistry ISO 9001:2015 Certified.
Leu-enkephalin(sulfated)
Leu-enkephalin(sulfated). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Leu-Enkephalin (sulfated);Leu-Enkephalin (sulfated) H-Tyr(SO3H)-Gly-Gly-Phe-Leu-OH. Product Category: Heterocyclic Organic Compound. CAS No. 80632-52-6. Molecular formula: C28H37N5O10S. Mole weight: 635.69. Product ID: ACM80632526. Alfa Chemistry ISO 9001:2015 Certified. Categories: Enkephalin-leu.
Leu-Gly-NH2·HBr. Group: Biochemicals. Alternative Names: L-Leucylglycine amide hydrobromide. Grades: Highly Purified. CAS No. 28671-28-5. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Leu-Gly-NH2·HBr 99+% (TLC)
Leu-Gly-NH2·HBr 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 28671-28-5. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
Leu-Gly-OH
This dipeptide inhibits the ubiquitin-mediated proteolysis. Synonyms: Leu Gly OH; L-Leucyl-glycine; (S)-2-(2-Amino-4-methylpentanamido)acetic acid. Grades: ≥ 99% (HPLC). CAS No. 686-50-0. Molecular formula: C8H16N2O3. Mole weight: 188.22.
Leu-Gly-OH
Leu-Gly-OH. Group: Biochemicals. Alternative Names: L-Leucyl-glycine. Grades: Highly Purified. CAS No. 686-50-0. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Leu-Gly-OH ≥95% (HPLC)
Leu-Gly-OH ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Leu-Gly-OH hydrochloride
Leu-Gly-OH hydrochloride. Group: Biochemicals. Grades: Reagent Grade. CAS No. 686-50-0(net). Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Leuhistin
It is produced by the strain of Bacillus laterosporus BMI 156-14F1. It inhibits aminopeptidase M with IC50 of 0.2 μg/mL. It has no antimicrobial effects (100 μg/mL). Synonyms: Leuhistine; (2R,3S)-2-((1H-imidazol-4-yl)methyl)-3-amino-2-hydroxy-5-methylhexanoic acid; 1H-Imidazole-4-propanoic acid, alpha-(1-amino-3-methylbutyl)-alpha-hydroxy-, (R-(R*,S*))-. Grades: 95%. CAS No. 129085-76-3. Molecular formula: C11H19N3O3. Mole weight: 241.29.
Leukadherin 1
Leukadherin 1. Group: Biochemicals. Grades: Purified. CAS No. 344897-95-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Leukadherin-1, also known as LA1, is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1. Leukadherin-1 suppresses human innate inflammatory signalling. leukadherin-1 increases CD11b/CD18-dependent adhesion via membrane tethers. It also competitively inhibits YopH (Ki = 1.94 μM), a tyrosine phosphorylase secreted by Y. pestis into immune cells to block signal transduction, and anthrax lethal factor metalloproteinase, a component of anthrax toxin (IC50 = 6 μM). Synonyms: 4-[5-[[4-Oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid; Leukadherin-1; Leukadherin 1; Leukadherin1; LA1. CAS No. 344897-95-6. Molecular formula: C22H15NO4S2. Mole weight: 421.48.
Leukadherin-1 (aMb2 Agonist II, CD11b Agonist II, LA1, Mac-1 Agonist II, CR3 Agonist II, CD11b/CD18 Agonist, 4-(5-((3-Benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl)furan-2-yl)-benzoic Acid)
A furanyl thiazolidinone compound that binds CD11b aA/aI domain in a reversible manner and stabilizes aA in a high-affinity binding conformation toward known CD11b/CD18 (aMB2; CR3; Mac-1) ligands, fibrinogen, ICAM-1, and iC3B. Reported to be superior to IMB-10 in enhancing Mac-1-mediated cell adhesion (EC50=4 vs. >50uM on fibrinogen surface). Effectively suppresses leukocyte recruitment in various inflammatory disease models involving mice, rats, and zebrafish embryos in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Leukemia Inhibitory Factor from mouse
LIF, recombinant, expressed in E. coli, 10 ?g/ml, buffered aqueous solution, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Leukemia Inhibitory Factor human
LIF, recombinant, expressed in E. coli, 10 ?g/ml, buffered aqueous solution (pH 7.4), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
leukocyte elastase
Differs from pancreatic elastase in specificity on synthetic substrates and in inhibitor sensitivity. In peptidase family S1 (trypsin family). Formerly included in EC 3.4.21.11. Group: Enzymes. Synonyms: lysosomal elastase; neutrophil elastase; polymorphonuclear leukocyte elastase; elastase; elaszym; serine elastase; lysosomal elastase; granulocyte elastase. Enzyme Commission Number: EC 3.4.21.37. CAS No. 9004-6-2. ELA2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4131; leukocyte elastase; EC 3.4.21.37; 9004-06-2; lysosomal elastase; neutrophil elastase; polymorphonuclear leukocyte elastase; elastase; elaszym; serine elastase; lysosomal elastase; granulocyte elastase. Cat No: EXWM-4131.
Leukotriene a3 methyl ester
Leukotriene a3 methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5S-TRANS-5,6-OXIDO-7E,9E,11Z-EICOSATRIENOIC ACID, METHYL ESTER;LTA3 METHYL ESTER;LEUKOTRIENE A3 METHYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 83851-38-1. Molecular formula: C21H34O3. Mole weight: 334.49. Purity: 0.96. IUPACName: methyl4-[(2S,3S)-3-[(1E,3E,5Z)-tetradeca-1,3,5-trienyl]oxiran-2-yl]butanoate. Canonical SMILES: CCCCCCCCC=CC=CC=CC1C(O1)CCCC(=O)OC. Density: 0.985g/cm³. Product ID: ACM83851381. Alfa Chemistry ISO 9001:2015 Certified.
leukotriene-A4 hydrolase
This is a bifunctional zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities. It preferentially cleaves tripeptides at an arginyl bond, with dipeptides and tetrapeptides being poorer substrates (see EC 3.4.11.6, aminopeptidase B). It also converts leukotriene A4 into leukotriene B4, unlike EC 3.3.2.10, soluble epoxide hydrolase, which converts leukotriene A4 into 5,6-dihydroxy-7,9,11,14-icosatetraenoic acid. In vertebrates, five epoxide-hydrolase enzymes have been identified to date: EC 3.3.2.6 (leukotriene A4 hydrolase), EC 3.3.2.7 (hepoxilin-epoxide hydrolase), EC 3.3.2.9 (microsomal epoxide hydrolase), EC 3.3.2.10 (soluble epoxide hydrolase) and EC 3.3.2.11 (cholesterol-5,6-oxide hydrolase). Group: Enzymes. Synonyms: LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase. Enzyme Commission Number: EC 3.3.2.6. CAS No. 90119-07-6. LTA4H. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4003; leukotriene-A4 hydrolase; EC 3.3.2.6; 90119-07-6; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase. Cat No: EXWM-4003.
Leukotriene A4 Hydrolase from Human, Recombinant
Leukotriene A4 Hydrolase human (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into Leukotriene B4, and also demonstrates aminopeptidase activity. Leukotriene B4 is a lipid chemoattractant that plays critical roles in inflammaton, immune responses, host defenses against infections, and lipid homeostasis. Inhibition of LTA4H in a mouse model decreases LTB4 in the airways and attenuates airway inflammation and airway hyperreactivity through modulation of T cell and dendritic cell function. Contains c-terminal his-tag. Applications: Leukotriene a4 hydrolase human (lta4h) is a drug target for anti-inflammation, and for cancer prevention and therapy. it is also suitable for screening inhibitors of leukotriene b4 synthesis. lta4h is used to study allergic asthma and airway hyperresponsiveness. Group: Enzymes. Synonyms: leukotriene-A4 hydrolase; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase; EC 3.3.2.6; 90119-07-6. Enzyme Commission Number: EC 3.3.2.6. CAS No. 90119-07-6. LTA4H. Mole weight: mol wt ~69 kDa. Storage: -70°C. Form: Supplied as a solution in 100mM Tris, pH 8.0, containing 20% glycerol and 100mM potassium chloride. Source: E. coli. Species: Human. leukotriene-A4 hydrolase; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H; leukotriene A4 hydrolase; EC 3.3.2.6; 90119-07-6. Cat No: NATE-0419.
Leukotriene A4 Hydrolase human
recombinant, expressed in E. coli. Group: Fluorescence/luminescence spectroscopy.
Leukotriene B
Leukotriene B4 is a chemokine with roles in inflammation, immunology, the nervous system, brain and skin. And it also shows antiviral activity towards DNA viruses and retroviruses. Synonyms: Leukotriene B4; LTB4; 5,12-Hete; 5,12-Dihete; (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid. Grades: ≥98%. CAS No. 71160-24-2. Molecular formula: C20H32O4. Mole weight: 336.47.
Leukotriene B4
Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LTB4; 5(S),12(R)-DiHETE. CAS No. 71160-24-2. Pack Sizes: 25 μg (297.2 μM * 250 μL in Ethanol). Product ID: HY-107608.
Leukotriene B4
~100 ?g/mL in ethanol, ?97%. Group: Fluorescence/luminescence spectroscopy.
leukotriene-B4 20-monooxygenase
A heme-thiolate protein (P-450). Not identical with EC 1.14.13.34, leukotriene-E4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.30. CAS No. 90119-11-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0837; leukotriene-B4 20-monooxygenase; EC 1.14.13.30; 90119-11-2; leukotriene-B4 20-hydroxylase; leucotriene-B4 ω-hydroxylase; LTB4 20-hydroxylase; LTB4 ω-hydroxylase. Cat No: EXWM-0837.
Leukotriene B4-3-aminopropylamide
Leukotriene B4-3-aminopropylamide is a LTB4 analog that exhibits high binding affinity for BLT1 receptor. Synonyms: LTB4-3-aminopropylamide; (5S,6Z,8E,10E,12R,14Z)-N-(3-aminopropyl)-5,12-dihydroxyicosa-6,8,10,14-tetraenamide. Grades: ≥95%. CAS No. 89596-43-0. Molecular formula: C23H40N2O3. Mole weight: 392.6.
Leukotriene B4 dimethyl amide
Leukotriene B4 dimethyl amide is a lipid mediator and Leukotriene B4 antagonist. It was shown to inhibit neutrophil degranulation induced by LTB4. Synonyms: LTB4 dimethyl amide; N,N-dimethyl-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraen-1-amide. Grades: ≥97%. CAS No. 83024-92-4. Molecular formula: C22H37NO3. Mole weight: 363.5.
Leukotriene B4 ethanolamide
Leukotriene B4 ethanolamide is a potent antagonist of leukotriene B4 receptor with 3-fold higher affinity than leukotriene B4. It exhibits anti-inflammatory activity. Synonyms: LTB4-EA; (5S,12R)-5,12-Dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide. Grades: ≥97%. CAS No. 877459-63-7. Molecular formula: C22H37NO4. Mole weight: 379.5.
Leukotriene B5
Leukotriene B5 is a leukotriene generated from eicosapentaenoic acid (EPA). LTB5 exhibits less potent biological activity than LTB4, thus it can be identified as a LTB4 antagonist. Study showed that LTB5 inhibited LTB4-induced chemotaxis in vitro and LTB4-induced proliferation in cultured human epidermal keratinocytes. Synonyms: LTB5; 5,12-DiHEPE; 5S,12S-dihydroxy-6Z,8E,14Z,17Z-eicosapentanenoic acid. Grades: ≥98%. CAS No. 80445-66-5. Molecular formula: C20H30O4. Mole weight: 334.5.
Leukotriene c3
Leukotriene c3. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Leukotriene C-3, Leukotriene C3, PDSP1_000718, PDSP2_000708, CID6438868, 5-Hydroxy-6-S-glutathionyl-7,9,11-eicosatrienoic acid, 77209-77-9, Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6-pentadecatrienyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z)))-. Product Category: Heterocyclic Organic Compound. CAS No. 77209-77-9. Molecular formula: C31H51N3O8S. Mole weight: 625.82. Purity: 0.96. IUPACName: (5S,7E,9E,11E)-6-[(2R)-2-[[(4S)-4-amino-5-hydroxy-5-oxopentanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11-trienoic acid. Product ID: ACM77209779. Alfa Chemistry ISO 9001:2015 Certified. Categories: Leukotriene C4 synthase.
Leukotriene C3
~50 ?g/mL in methanol: water (7:3) containing 17 mM acetate buffer adjusted to pH 5.4 with NH4OH, ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Leukotriene C4
Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4; 5S,6R-Ltc(sub 4); 6R-(((R)-2-((S)-4-amino-4-carboxybutanamido)-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5S-hydroxyicosa-7E,9E,11Z,14Z-eicosatetraenoic acid. Grades: ≥97%. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.78.
Leukotriene C4
Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 72025-60-6. Pack Sizes: 25 μg (159.8 μM * 250 μL in Ethanol). Product ID: HY-113446.
LEUKOTRIENE C4
LEUKOTRIENE C4. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Leukotriene C4 Lipid. Appearance: Colorless liquid. CAS No. 72025-60-6. Molecular formula: C30H47N3O9S. Mole weight: 625.77. Purity: 0.97. Product ID: ACM72025606. Alfa Chemistry ISO 9001:2015 Certified. Categories: Leukotriene C4 synthase.
leukotriene-C4 hydrolase
The mouse enzyme is specific for leukotriene C4, while the human enzyme also has considerable activity towards glutathione and oxidized glutathione (cf. EC 3.4.19.13, glutathione hydrolase). Group: Enzymes. Synonyms: γ-glutamyl leukotrienase; GGT5. Enzyme Commission Number: EC 3.4.19.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4086; leukotriene-C4 hydrolase; EC 3.4.19.14; γ-glutamyl leukotrienase; GGT5. Cat No: EXWM-4086.
Leukotriene C4 methyl ester
Leukotriene C4 is a cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 acts as an agonist of smooth muscle contraction. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. Synonyms: LTC4 methyl ester; Leukotriene C4 monomethyl ester. Grades: ≥97%. CAS No. 73958-10-8. Molecular formula: C31H49N3O9S. Mole weight: 639.8.
leukotriene-C4 synthase
The reaction proceeds in the direction of addition. Not identical with EC 2.5.1.18, glutathione transferase. Group: Enzymes. Synonyms: leukotriene C4 synthetase; LTC4 synthase; LTC4 synthetase; leukotriene A4:glutathione S-leukotrienyltransferase; (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathioneleukotriene-transferase (epoxide-ring-opening); (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming). Enzyme Commission Number: EC 4.4.1.20. CAS No. 90698-32-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5322; leukotriene-C4 synthase; EC 4.4.1.20; 90698-32-1; leukotriene C4 synthetase; LTC4 synthase; LTC4 synthetase; leukotriene A4:glutathione S-leukotrienyltransferase; (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathioneleukotriene-transferase (epoxide-ring-opening); (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming). Cat No: EXWM-5322.
Leukotriene D4
Leukotriene D4 is a constituent of slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-; Glycine, N-[S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinylglycine; Leukotriene D; LTD4. Grades: ≥97%. CAS No. 73836-78-9. Molecular formula: C25H40N2O6S. Mole weight: 496.66.
Leukotriene D4
Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 73836-78-9. Pack Sizes: 10 μg (201.34 μM * 100 μL in Ethanol); 50 μg (201.34 μM * 500 μL in Ethanol). Product ID: HY-113456.
Leukotriene D4 methyl ester is a derivate of Leukotriene D4, which is a constituent of a slow-reacting substance of anaphylaxis (SRS-A) and acts as an agonist of smooth muscle contraction. LTD4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. Synonyms: LTD4 methyl ester; Leukotriene D4 monomethyl ester; Glycine, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-1-hydroxy-5-methoxy-5-oxopentyl]-2,4,6,9-pentadecatetraenyl]-L-cysteinyl-; Glycine, N-[S-[1-(1-hydroxy-5-methoxy-5-oxopentyl)-2,4,6,9-pentadecatetraenyl]-L-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteinylglycine. Grades: 95%. CAS No. 103476-23-9. Molecular formula: C26H42N2O6S. Mole weight: 510.69.
Leukotriene E4
Leukotriene E4 is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid; LTE4. Grades: ≥97%. CAS No. 75715-89-8. Molecular formula: C23H37NO5S. Mole weight: 439.61.
Leukotriene E4
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma. Uses: Scientific research. Group: Natural products. Alternative Names: LTE4. CAS No. 75715-89-8. Pack Sizes: 25 μg (227.47 μM * 250 μL in Ethanol); 50 μg (227.47 μM * 500 μL in Ethanol); 100 μg (227.47 μM * 1 mL in Ethanol). Product ID: HY-113465.
leukotriene-E4 20-monooxygenase
Also acts on N-acetyl-leukotriene E4, but more slowly. Not identical with EC 1.14.13.30 leukotriene-B4 20-monooxygenase. Group: Enzymes. Synonyms: leukotriene-E4 ω-hydroxylase. Enzyme Commission Number: EC 1.14.13.34. CAS No. 111940-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0841; leukotriene-E4 20-monooxygenase; EC 1.14.13.34; 111940-51-3; leukotriene-E4 ω-hydroxylase. Cat No: EXWM-0841.
Leukotriene E4 methyl ester
Leukotriene E4 methyl ester is a derivate of Leukotriene E4, which is a cysteinyl leukotriene produced by LTD4 and LTC4 in breath condensation, plasma, and urine. It is a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is the final product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, thus it can be used as an indicator in clinical diagnosis of asthma. Synonyms: 7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-, 1-methyl ester, (5S,6R,7E,9E,11Z,14Z)-; 1-Methyl (5S,6R,7E,9E,11Z,14Z)-6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-7,9,11,14-eicosatetraenoate; 7,9,11,14-Eicosatetraenoic acid, 6-[(2-amino-2-carboxyethyl)thio]-5-hydroxy-, 1-methyl ester, [5S-[5R*,6S*(S*),7E,9E,11Z,14Z]]-; S-((5S,6R,7E,9E,11Z,14Z)-5-hydroxy-1-methoxy-1-oxoicosa-7,9,11,14-tetraen-6-yl)-L-cysteine; LTE4, methyl ester; leukotriene E4 monomethyl ester. Grades: ≥95%. CAS No. 89461-65-4. Molecular formula: C24H39NO5S. Mole weight: 453.64.
Leu-Leu-Leu-OH
Leu-Leu-Leu-OH. Group: Biochemicals. Alternative Names: L-Leucyl-L-leucyl-L-leucine. Grades: Highly Purified. CAS No. 10329-75-6. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Leu-Leu-Leu-OH
Synonyms: L-Leucyl-L-leucyl-L-leucine; Leu Leu Leu OH. Grades: ≥ 96% (Elemental Analysis). CAS No. 10329-75-6. Molecular formula: C18H35N3O4. Mole weight: 357.49.
Leu-Leu-Leu-OH ≥96%
Leu-Leu-Leu-OH ≥96%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 10329-75-6. Pack Sizes: 250mg, 1g. US Biological Life Sciences.
Worldwide
Leu-Leu-OH
Synonyms: L-Leucyl-L-leucine; Leu Leu OH. Grades: ≥ 96% (HPLC). CAS No. 3303-31-9. Molecular formula: C12H24N2O3. Mole weight: 244.33.
Leu-Leu-OH
Leu-Leu-OH. Group: Biochemicals. Alternative Names: L-Leucyl-L-leucine. Grades: Highly Purified. CAS No. 3303-31-9. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences.