A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Antiarrhythmic (class IB). Group: Biochemicals. Alternative Names: 1-(2,6-Dimethylphenoxy)-2-propanamine Hydrochloride; 1-Methyl-2-(2,6-xylyloxy)ethylamine Hydrochloride; Katen; Ko 1173; Ko 1173Cl; Mexilitene; Mexitil; Ritalmex. Grades: Highly Purified. CAS No. 5370-1-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Mexiletine Impurity 10
Mexiletine Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123363-66-6. Molecular formula: C11H18ClNO2. Mole weight: 231.72. Catalog: APB123363666.
Mexiletine Impurity 21
Mexiletine Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329835-60-0. Molecular formula: C11H12D6ClNO. Mole weight: 221.76. Catalog: APB1329835600.
Mexilitine
Mexiletine is a non-selective voltage-gated sodium channel blocker used to treat arrhythmias within the heart, or seriously irregular heartbeats. Uses: Used to treat arrhythmias within the heart, or seriously irregular heartbeats. Synonyms: Mexiletine, Mexitil, Mexiletene, KO-1173, KO 1173, KO1173; 1-(2,6-dimethylphenoxy)-2-propanamin; 1-methyl-2-(2,6-xylyloxy)-ethylamin; 1-Methyl-2-(2,6-xylyloxy)ethylamine; 2-Propanamine, 1-(2,6-dimethylphenoxy)-; Ethylamine, 1-methyl-2-(2,6-xylyloxy)-. Grades: ≥98%. CAS No. 31828-71-4. Molecular formula: C11H17NO. Mole weight: 179.26.
Mexobamol impurity 1
Mexobamol impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10488-39-8. Molecular formula: C11H15NO5. Mole weight: 241.24. Catalog: APB10488398.
Mexobamol impurity 3
Mexobamol impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329610-40-3. Molecular formula: C11H15NO8S. Mole weight: 321.3. Catalog: APB1329610403.
Mezagitamab
Mezagitamab (TAK-079) is a IgG1λ anti- CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TAK-079. CAS No. 2227490-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99730.
Mezigdomide
Mezigdomide is a new type of protein degrading agent, a cereblon E3 ubiquitin ligase modulating drug, with potential immunomodulatory and anti-tumor activity. Synonyms: CC-92480; CC 92480; CC92480. Grades: >98% by HPLC. CAS No. 2259648-80-9. Molecular formula: C32H30FN5O4. Mole weight: 567.6.
Mezigdomide
Mezigdomide (CC-92480), a cereblon E3 ubiquitin ligase modulating agent (CELMoD), acts as a molecular glue. Mezigdomide shows high affinity to cereblon, resulting in potent antimyeloma activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-92480. CAS No. 2259648-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129395.
Mezlocillin
Mezlocillin is a broad-spectrum, beta-lactam penicillin antibiotic with antibacterial activity. It belongs semisynthetic ampicillin-derived acylureido penicillin. It is active against both Gram-negative and some Gram-positive bacteria. It inhibits the third and last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections. It is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. Uses: Mezlocillin has antibacterial activity. it is active against both gram-negative and some gram-positive bacteria. it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. Synonyms: BAY-f 1353; 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid; [2S- [2α , 5α , 6β (S*) ] ] -3, 3-Dimethyl-6- [ [ [ [ [3- (methylsulfonyl) -2-oxo-1-imidazolidinyl] carbonyl] amino] phenylacetyl] amino] -7-oxo-4-thia-1-azabicyclo [3. 2. 0] heptane-2-carboxylic Acid; Mezlin; Mezlocillinum; Mezlocilina; Mezlocilline. Grades: ≥98%. CAS No. 51481-65-3. Molecular formula: C21H25N5O8S2. Mole weight: 539.58.
Mezlocillin
Mezlocillin. Group: Biochemicals. Grades: Highly Purified. CAS No. 51481-65-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-f 1353 sodium. CAS No. 42057-22-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1466.
Mezlocillin sodium
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H24N5NaO8S2. CAS No. 59798-30-0. Prepack ID 77075760-100mg. Molecular Weight 561.56. See USA prepack pricing.
Mezlocillin sodium
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Mezlocillin Sodium
Mezlocillin Sodium. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
MF-094
MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2241025-68-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112438.
MF498
MF498 is a novel and selective E prostanoid receptor 4 (EP4 receptor) antagonist, a Gs protein-coupled receptor, with Ki of 0.7 nM. It plays important roles in bone formation and resorption, inflammation, cancer, and atherosclerosis. It has been shown to inhibit inflammation without gastrointestinal toxicity in various animal models for arthritis. It also displays a relatively good selectivity over other prostanoid receptors. It does not compromise the mucosal integrity in the gastrointestinal tract in vitro. It inhibits PGE2-stimulated cAMP accumulation in a dose-dependent manner. It relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis in vivo. Uses: Mf498 plays important roles in bone formation and resorption, inflammation, cancer, and atherosclerosis. it has been shown to inhibit inflammation without gastrointestinal toxicity in various animal models for arthritis. it relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis in vivo. Synonyms: MF498; MF 498; MF-498; C 528911; C-528911; C528911; N-[[[4-(5,9-Diethoxy-6,8-dihydro-6-oxo-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methyl]sulfonyl]-2-methoxy-benzeneacetamide;N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-methoxyphenyl)acetamide. Grades: >98%. CAS No. 915191-42-3. Molecular formula: C32H33N3O7S. Mole weight: 603.69.
MF592
MF592 is a potent and selective antagonists of the EP4 receptor. It has good functional potency and potent inhibition of PGE2 modulated TNFa release in LPS stimulated human whole blood (hWB). It displays an excellent oral pharmacokinetic (PK) profile and in vivo efficacy in a rat chronic adjuvant-induced-arthritis model. It has a desirable overall preclinical profile that suggests it is suitable for further development. Synonyms: MF-592; MF 592; MF592; 2, 6-Dichloro-N- ( (1- (4- (4, 9-diethoxy-1-oxo-1, 3-dihydro-2H-benzo[f]isoindol-2-yl) -3-methylbenzyl) cyclopropyl) carbamoyl) benzenesulfonamide. Grades: >98%. CAS No. 1064195-48-7. Molecular formula: C34H33Cl2N3O6S. Mole weight: 682.61.
Mf-63
Mf-63 is a selective Microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. Its IC50 value is 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively. It displays greater than 1,000-fold selectivity over other prostanoid synthases. It strongly inhibited guinea pig mPGES-1 but not the mouse or rat enzyme in rodent species. It did not cause NSAID-like gastrointestinal toxic effects that is caused by non-selective COX inhibitors, although it markedly suppresses PGE2 synthesis in the stomach. It prevents LPS-induced hyperglasia. It has anti-inflammatory, analgesic and anti-cancer agent. Uses: Mf-63 has anti-inflammatory, analgesic and anti-cancer agent. Synonyms: 2-(9-Chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-1,3-benzenedicarbonitrile;2-(6-chloro-1H-phenanthro-[9,10-d]iMidazol-2-yl)isophthalonitrile;MF-63; MF63; MF 63. Grades: >98%. CAS No. 892549-43-8. Molecular formula: C23H11ClN4. Mole weight: 378.81.
Mfa-hst5
Mfa-hst5 is from Macaca fascicularis and has antifungal, Candida spp. and Criptococcus spp. activities.
MF-EA-705alpha
It is originally isolated from Streptomyces sp. MF-EA-705. And the MIC of MF-EA-705alpha against Candida albicans was 1 g/mL. Molecular formula: C20H22O2. Mole weight: 294.39.
MF-EA-705beta
MF-EA-705beta is an antifungal antibiotic isolated from Streptomyces sp. MF-EA-705. Synonyms: (3E,5E,7Z)-8-{2-[(1Z)-but-1-en-1-yl]-4-methylphenyl}nona-3,5,7-trienoic acid. Molecular formula: C20H24O2. Mole weight: 294.39.
Mfe I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑AATTG GTTAA↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Mfe I from Mycoplasma fermentans. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1131RE.
MFI8
MFI8 is a small molecule inhibitor of mitochondrial[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 694488-83-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-150031.
m-Fluoro-DL-phenylalanine
m-Fluoro-DL-phenylalanine. Uses: Cell analysis peptide synthesis. Additional or Alternative Names: 3-Fluoro-DL-phenylalanine. Product Category: Amino Acids. CAS No. 456-88-2. Molecular formula: FC6H4CH2CH(NH2)COOH. Mole weight: 183.18. Canonical SMILES: NC(Cc1cccc(F)c1)C(O)=O. ECNumber: 220-104-1. Product ID: ACM456882-1. Alfa Chemistry ISO 9001:2015 Certified.
m-Fluoro Prasugrel Thiolactone (Mixture of Diastereomers)
An Intermediate in the synthesis of m-Fluoro Prasugrel. Synonyms: 5-[2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: > 95%. CAS No. 1618107-97-3. Molecular formula: C18H18FNO2S. Mole weight: 331.41.
m-Fluoro Prasugrel Thiolactone. (Mixture of Diastereomers)
Intermediate in the synthesis of m-Fluoro Prasugrel (F595870). Group: Biochemicals. Alternative Names: 5-[2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
MFZ 10-7
MFZ 10-7 is a mGlu5 receptor negative allosteric modulator. It can inhibit mGlu5 glutamate-mediated calcium mobilization with IC50 value of 1.22 nM. MFZ 10-7 can inhibit cocaine-taking and cocaine-seeking behavior in rats. Synonyms: 3-Fluoro-5-[2-(6-methyl-2-pyridinyl)ethynyl]benzonitrile hydrochloride. Grades: ≥99% by HPLC. CAS No. 1224431-15-5. Molecular formula: C15H9FN2.HCl. Mole weight: 272.7.
MFZ 10-7
MFZ 10-7. Group: Biochemicals. Grades: Purified. CAS No. 1224431-15-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MFZ 10-7
MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a K i of 0.67 nM for rat mGluR5 [1]. MFZ 10-7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1224431-15-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103575.
MG 101. Group: Biochemicals. Grades: Purified. CAS No. 110044-82-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
MG-101
MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K i s of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain inhibitor I; Ac-LLnL-CHO; ALLN. CAS No. 110044-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18964.
MG-115 - CAS 133407-86-0
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively). Group: Fluorescence/luminescence spectroscopy.
A potent, reversible proteasome inhibitor with Ki of 21nM for 20S proteasome and 35nM for 26S proteasome. The inhibition of proteasome was through specific inhibition of chymotrypsin-like activity of the proteasome. Also shown to induce apoptosis in Rat-1 and PC12 cells via a p3-independent pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC 50 s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Leu-Leu-Leu-al; MG132. CAS No. 133407-82-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13259.
MG-132
MG-132 is a potent Proteasome inhibitor with potential anticancer activity. MG-132 induces MCPIP1 expression; induces C6 glioma cell apoptosis via oxidative stress; induces AIF nuclear translocation through down-regulation of ERK and Akt/mTOR pathway. Synonyms: Z-Leu-leu-leu-al. CAS No. 133407-82-6. Molecular formula: C26H41N3O5. Mole weight: 475.62.
MG-132, ?95% by HPLC - CAS 133407-82-6
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). Group: Fluorescence/luminescence spectroscopy.
MG-132 - CAS 133407-82-6
A cell-permeable, potent, reversible proteasome inhibitor (Ki = 4 nM). Group: Fluorescence/luminescence spectroscopy.
MG-132 (negative control)
MG-132 negative control is the negative control form of MG-132 (HY-13259). MG-132 is a potent proteasome and calpain inhibitor[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13259D.
MG-132 (Z-Leu-Leu-Leu-CHO)
Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kB activation inhibitor through IκB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin inhibitor. Has anticancer properties by inducing cell cycle arrest and activating apoptosis in various cancer cell lines. Has adjuvant / chemosensitizer potential. Neurite outgrowth stimulator in PC12 cells. Prevents beta-secretase cleavage. Autophagy activator. Group: Biochemicals. Alternative Names: Z-Leu-Leu-Leu-al; Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal; Proteasome Inhibitor XI). Grades: Highly Purified. CAS No. 133407-82-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C26H41N3O5, Sequence: Z-Leu-Leu-Leu-aldeyhde. US Biological Life Sciences.
Worldwide
MG149
MG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF,respectively. Synonyms: MG149; MG 149; MG-149. Grades: >98%. CAS No. 1243583-85-8. Molecular formula: C22H28O3. Mole weight: 340.46.
MG 149
MG149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF (IC50= 47 uM); little potent for PCAF and p300 (IC50 >200 uM)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tip60 HAT inhibitor. CAS No. 1243583-85-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15887.
MG 149
MG 149. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1243583-85-8. Molecular formula: C22H28O3. Mole weight: 340.46. Catalog: APB1243583858.
MG-262
MG-262 (Z-Leu-Leu-LeuB(OH)2; ZL3B) is a reversible proteasome inhibitor. MG-262 down-regulates VEGF receptor Flt-1. MG-262 inhibits cell growth and induces apoptosis in malignant cells. MG-262 induces reactive oxygen species (ROS). MG-262 can be used for anti-cancer study[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Leu-Leu-LeuB(OH)2; ZL3B. CAS No. 179324-22-2. Pack Sizes: 1 mg. Product ID: HY-108551.
Mg2+-importing ATPase
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme occurs in both Gram-positive and Gram-negative bacteria, and three types are known, designated as CorA, MgtA and MgtB. The CorA itself is not an ATPase but an Mg2+ transporter. Group: Enzymes. Enzyme Commission Number: EC 3.6.3.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4656; Mg2+-importing ATPase; EC 3.6.3.2. Cat No: EXWM-4656.
MG 624
MG624 is a neuronal nicotinic acetylcholine receptors antagonist. It is selective for neuronal nAChRs over muscle-type AChRs. It can decrease vagus nerve stimulation-induced contractions of isolated guinea pig vagus nerve-stomach preparations. Synonyms: MG624; MG 624; MG-624; N,N,N-Triethyl-2-[4-(2-phenylethenyl)phenoxy]ethanaminium iodide. Grades: ≥98% by HPLC. CAS No. 77257-42-2. Molecular formula: C22H30NOI. Mole weight: 451.39.
MG 624. Group: Biochemicals. Grades: Purified. CAS No. 77257-42-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MGA271
Enoblituzumab is a monoclonal antibody designed for the treatment of cancer. Formerly known as MGA271, the drug is a humanized IgG1κ monoclonal antibody recognizing human. B7-H3, a member of the B7 family of immune regulators. Synonyms: MGA271; MGA 271; MGA-271; Enoblituzumab; UNII-M6030H73N9. CAS No. 1353485-38-7. Molecular formula: C6474H9990N1726O2030S42.
MGA-C13
This glucoside shows remarkable behavior for the stabilization of a variety of membrane proteins including transporters and GPCRs. The presence of glucoside head group is beneficial to the formation of small complexes with membrane proteins and the formation of high quality protein crystal and clear visualization via CryoEM. Synonyms: Mesitylene-cored glucoside amphiphile-C13. Grades: >99%. CAS No. 2102603-26-7. Molecular formula: C93H168O36. Mole weight: 1862.34.
MGAT2-IN-1
An orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) (IC50= 7.8 for human, and 2.4 nM for mouse MGAT2). Synonyms: N-(4-chloro-2,6-difluorophenyl)-1-[5-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]pyrimidin-2-yl]-7-(2-oxopyrrolidin-1-yl)-2,3-dihydroindole-5-sulfonamide. CAS No. 1800025-30-2. Molecular formula: C27H21ClF5N7O3S. Mole weight: 654.01.
MGAT5 (intro)
The MGAT5 gene encodes mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides.
MGB-BP-3
MGB-BP-3 is an antibiotic that has been shown to be active against a broad range of important multi-resistant Gram-positive pathogens. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000277-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00035.
MGB Eclipse® CPG
MGCD-265
MGCD-265. Group: Biochemicals. Alternative Names: N- [ [ [3-Fluoro-4- [ [2- (1-methyl-1H-imidazol-4-yl) thieno [3, 2-b] pyridin-7-yl] oxy] phenyl] amino] thioxomethyl] -benzeneacetamide. Grades: Highly Purified. CAS No. 875337-44-3. Pack Sizes: 5mg. Molecular Formula: C26H20FN5O2S2, Molecular Weight: 517.6. US Biological Life Sciences.
Worldwide
MGCD-265
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively and also inhibits Ron and Tie2. Synonyms: MGCD-265; MGCD 265; MGCD265; MGCD-265-analog; MGCD 265-analog; MGCD265-analog. Glesatinib-analog. Grades: >98%. CAS No. 875337-44-3. Molecular formula: C26H20FN5O2S2. Mole weight: 517.60.
MGCD-265 analog
MGCD-265 analog is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC 50 s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875337-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10991.
MGF
Mechano growth factor (MGF) is a spliced variant of insulin-like growth factor 1 (IGF-1). IGF-1 is found in various tissues in the body including liver and muscle. Synonyms: MGF E-domain; IGF-1 EC; Mechano Growth Factor. Grades: 98%. Molecular formula: C121H199N40O40. Mole weight: 2868.19.
MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896657-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139330.
MGK 264. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(2-Ethylhexyl)-5-norbornene-2,3-dicarboximide. Product Category: Amide & Amine Monomers. Appearance: Colourless or Light Yellow Liquid. CAS No. 113-48-4. Molecular formula: C17H25NO2. Mole weight: 275.39 g/mol. Purity: 0.95. Product ID: ACM-MO-113484. Alfa Chemistry ISO 9001:2015 Certified.
MGK-264
MgK-264 (N-octylbicycloheptenedicarboximide) is a synergist enhancing the potency of pyrethroid ingredients. MgK-264 has no intrinsic pesticidal qualities itself [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Octylbicycloheptenedicarboximide; ENT 8184. CAS No. 113-48-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W013170.
MGL-3196
MGL-3196 is a first-in-class, orally available, once-daily and liver-directed thyroid hormone receptor (THR) beta-selective agonist. Studies suggest that MGL-3196 has an attractive, differentiated profile as a potential treatment for non-alcoholic steatohepatitis (NASH) and dyslipidemias. Uses: Potential treatment for non-alcoholic steatohepatitis (nash) and dyslipidemias. Synonyms: CHEMBL3261331; UNII-RE0V0T1ES0; MGL-3196; MGL 3196; MGL3196; VIA 3196; VIA3196; VIA-3196; Resmetirom.RE0V0T1ES0; 2-[3,5-dichloro-4-[(6-oxo-5-propan-2-yl-1H-pyridazin-3-yl)oxy]phenyl]-3,5-dioxo-1,2,4-triazine-6-carbonitrile. CAS No. 920509-32-6. Molecular formula: C17H12Cl2N6O4. Mole weight: 435.211.
mGluR5 Antagonist, MTEP - CAS 329205-68-7
The mGluR5 Antagonist, MTEP, also referenced under CAS 329205-68-7, controls the biological activity of mGluR5. This small molecule/inhibitor is primarily used for Neuroscience applications. Group: Fluorescence/luminescence spectroscopy.
mGluR5 Ligand, CDPPB - CAS 781652-57-1
A pyrazole amide compound that crosses the blood-brain barrier and acts as a potent, selective, reversible, positive allosteric modulator for metabotropic glutamate receptor subtype 5 (mGluR5). Group: Fluorescence/luminescence spectroscopy.