A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Microtubule-associated protein 1A (806-814) is a fragment of MAP1A. Microtubule-associated protein MAP1A is expressed abundantly in mature neurons and is necessary for maintenance of neuronal morphology and localization of some molecules in association with the microtubule-based cytoskeleton. It can be used in Ovarian carcinoma research.
microtubule-severing ATPase
Another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome. Group: Enzymes. Enzyme Commission Number: EC 3.6.4.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4705; microtubule-severing ATPase; EC 3.6.4.3. Cat No: EXWM-4705.
Microtubule-Targeted Compound Library
A unique collection of 80 microtubule-targeted compounds can be used in HTS and HCS; - Detailed compound information with structure, target, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1110. Categories: Microtubule-Targeted Compounds Libraries.
MID-1
MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312608-54-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115461.
Midasin (1471-1481)
Midasin (1471-1481) is amino acids 1471 to 1481 fragment of Midasin. Midasin is a member of the AAA(+) family of ATPases. It is a nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Synonyms: Dynein-related AAA-ATPase MDN1 (1471-1481). Grades: >98%.
Midazolam EP Impurity A
Midazolam EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59468-07-4. Molecular Formula: C18H15ClFN3. Mole Weight: 327.79. Catalog: APB59468074.
Midazolam EP Impurity B
Midazolam EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59469-74-8. Molecular Formula: C18H13ClFN3. Mole Weight: 325.77. Catalog: APB59469748.
Midazolam EP Impurity C
Midazolam EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59468-44-9. Molecular Formula: C19H13ClFN3O2. Mole Weight: 369.78. Catalog: APB59468449.
Midazolam EP Impurity F
Midazolam EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2886-65-9. Molecular Formula: C15H10ClFN2O. Mole Weight: 288.71. Catalog: APB2886659.
Midazolam EP Impurity G
Midazolam EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59467-86-6. Molecular Formula: C18H14ClN3. Mole Weight: 307.78. Catalog: APB59467866.
Midazolam EP Impurity I
Midazolam EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59467-69-5. Molecular Formula: C18H15ClFN3. Mole Weight: 327.79. Catalog: APB59467695.
Midazolam EP Impurity J
Midazolam EP Impurity J. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59469-08-8. Molecular Formula: C18H17ClFN3. Mole Weight: 329.8. Catalog: APB59469088.
Midazolam Impurity 11
Midazolam Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 60656-76-0. Molecular Formula: C16H11ClFN3O3. Mole Weight: 347.73. Catalog: APB60656760.
Midazolam Impurity 12
Midazolam Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59468-90-5. Molecular Formula: C18H13ClFN3O. Mole Weight: 341.77. Catalog: APB59468905.
Midazolam Impurity 14
Midazolam Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59468-73-4. Molecular Formula: C18H17Cl3FN3O. Mole Weight: 416.7. Catalog: APB59468734.
Midazolam Impurity 15
Midazolam Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59469-32-8. Molecular Formula: C20H20FN3O4. Mole Weight: 385.4. Catalog: APB59469328.
Midazolam Impurity 16
Midazolam Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59469-33-9. Molecular Formula: C18H16FN3. Mole Weight: 293.35. Catalog: APB59469339.
Midazolam Impurity 17
Midazolam Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59468-85-8. Molecular Formula: C18H13ClFN3O. Mole Weight: 341.77. Catalog: APB59468858.
Midazolam Impurity 18
Midazolam Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 55075-93-9. Molecular Formula: C14H8ClFN2. Mole Weight: 258.68. Catalog: APB55075939.
Midazolam Impurity 19
Midazolam Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 57698-59-6. Molecular Formula: C15H11ClFNO2. Mole Weight: 291.71. Catalog: APB57698596.
Midazolam Impurity 20
Midazolam Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 871514-02-2. Molecular Formula: C17H11ClFN3. Mole Weight: 311.74. Catalog: APB871514022.
Midazolam Impurity 21
Midazolam Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 84425-62-7. Molecular Formula: C18H15ClFN3O. Mole Weight: 343.79. Catalog: APB84425627.
Midecamycin
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: SF-837; Antibiotic SF-837. CAS No. 35457-80-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1908.
Midecamycin
Midecamycin. Group: Biochemicals. Alternative Names: Leucomycin V 3,4B-dipropanoate; Aboren; Antibiotic SF 837. Grades: Highly Purified. CAS No. 35457-80-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C41H67NO15. US Biological Life Sciences.
Worldwide
Midecamycin
Midecamycin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 35457-80-8. Molecular Formula: C41H67NO15. Mole Weight: 813.98. Catalog: APB35457808.
Midecamycin A2
Midecamycin A2 is a macrolide compound produced by Streptomyces mycarofaciens. It has strong anti-Gram-positive bacteria and weak anti-Gram-negative bacteria, mycobacteria and fungi activity. Cross-resistance with erythromycin. Synonyms: Antibiotic SF 837A2. Molecular formula: C42H69NO15. Mole weight: 827.99.
Midecamycin A3
Midecamycin A3 is a macrolide compound produced by Streptomyces mycarofaciens. It has strong anti-Gram-positive bacteria and weak anti-Gram-negative bacteria, mycobacteria and fungi activity. Cross-resistance with erythromycin. Synonyms: Mydecamycin A3; Antibiotic SF 837 A3. Molecular formula: C41H65NO15. Mole weight: 811.95.
Midecamycin A4
Midecamycin A4 is a macrolide compound produced by Streptomyces mycarofaciens. It has strong anti-Gram-positive bacteria and weak anti-Gram-negative bacteria, mycobacteria and fungi activity. Cross-resistance with erythromycin. Synonyms: Mydecamycin A4; Antibiotic SF 837A4. Molecular formula: C42H67NO15. Mole weight: 825.98.
Midgut defensin
Midgut defensin is isolated from Haemaphysalis longicornis and has antibacterial activity.
Midkine (114-122)
Midkine, a heparin-binding growth factor, contains 121 amino acid residues with 5 disulfide bonds. It promotes the growth, survival, and migration of various cells, and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. Synonyms: MK (114-122); MDK (114-122).
Midkine (13-21)
Midkine, a heparin-binding growth factor, contains 121 amino acid residues with 5 disulfide bonds. It promotes the growth, survival, and migration of various cells, and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. Synonyms: MK (13-21); MDK (13-21).
Midkine (9-23)
Midkine, a heparin-binding growth factor, contains 121 amino acid residues with 5 disulfide bonds. It promotes the growth, survival, and migration of various cells, and plays roles in neurogenesis and epithelial mesenchymal interactions during organogenesis. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. Synonyms: MK (9-23); MDK (9-23).
A cell-permeable imidazothiazolyl-chromenone compound that reduces cellular midkine/MDK protein level in H441 lung adenocarcinoma cells in a dose-dependent manner (by >90% in 48h at 25nM) via a yet unidentified mechanism. Shown to inhibit the viability of MDK-positive HEK293, H441, and H520 cells (by ≥60% at 500nM in 48h), but not MDK-negative NHLF or HEK293 (by <15% at 500nM in 48h), via apoptosis induction as a result of PI 3-K/AKT signaling inhibition. Intraperitoneal injection is reported to be efficacious in retarding H441 tumor expansion in mice (9mg/kg; 3X to 5X per wk) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O?S. US Biological Life Sciences.
Worldwide
Midodrine
Midodrine is an α1-receptor agonist and exerts its actions via activation of the alpha-adrenergic receptors of the arteriolar and venous vasculature. Synonyms: 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide; (±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol. Grades: ≥95%. CAS No. 42794-76-3. Molecular formula: C12H18N2O4. Mole weight: 254.28.
Midodrine
Midodrine is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Midodrin. CAS No. 42794-76-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12749.
midodrine hydrochloride
A phenylalkanolamine derivative which has been found to be effective in treating hypertensive conditions due to their long lasting blood pressure increasing effects. Synonyms: Midodrine HCl; Pro-Amatine. Grades: 95%. CAS No. 3092-17-9. Molecular formula: C12H18N2O4.HCl. Mole weight: 290.75.
Midodrine hydrochloride
Midodrine hydrochloride. Group: Biochemicals. Alternative Names: ST-1085, amatine, gutron, hipertan, metligine, proAmatine. Grades: Highly Purified. CAS No. 3092-17-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H19ClN2O4. US Biological Life Sciences.
Worldwide
Midodrine hydrochloride
Midodrine hydrochloride ((±)-Midodrine hydrochloride) is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Midodrine hydrochloride. CAS No. 43218-56-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12749A.
A phenylalkanolamine derivative which has been found to be effective in treating hypertensive conditions due to their long lasting blood pressure increasing effects. Group: Biochemicals. Alternative Names: ST-1085, Amatine, Gutron, Hipertan, Metligine, ProAmatine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Midodrine (metoclopramide). Uses: For analytical and research use. Group: Impurity standards. CAS No. 42794-76-3. Molecular Formula: C12H18N2O4. Mole Weight: 254.29. Catalog: APB42794763.
Midodrine Related Compound A (Desglymidodrine)
Desglymidodrine is a metabolite of Midodrine. It induces alpha-adrenergic receptor stimulation of both arterial and venous systems without direct central nervous systme of cardiac effects. Synonyms: 1-(2',5'-Dimethoxyphenyl)-2-aminoethanol; α-(Aminomethyl)-2,5-dimethoxy-benzyl Alcohol; α-(Aminomethyl)-2,5-dimethoxy-benzenemethanol; de-Glymidodrine, Desglymidodrine. Grades: > 95%. CAS No. 3600-87-1. Molecular formula: C10H15NO3. Mole weight: 197.23.
Midostaurin
Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ , Syk , Flk-1 , Akt , PKA , c-Kit , c-Fgr , c-Src , FLT3 , PDFRβ and VEGFR1/2 with IC 50 s ranging from 22-500 nM [1] [2]. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PKC412; CGP 41251. CAS No. 120685-11-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10230.
Mid-temperature desizing enzyme
Mid-temperature desizing enzyme is a new enzyme preparation, concentrated and with high thermal stability. It is used for desize starch, starch derivative, the mixed slurry of starch and PVA. Applications: Be suitable for hot bath, cold stack, continuous desizing in wide temperature range. Group: Enzymes. Desizing enzyme. Appearance: liquid. desizing; Mid-temperature desizing enzyme; Mid-temperature Textile; Desizing Enzyme; desize starch Textile; Mid-temperature desizing enzyme; TEXT-1926. Pack: 25kg/barrel or subject to client requirement. Cat No: TEXT-1926.
Mid-temperature Refining α-Amylase for beer
Mid-temperature a-amylase is extracted from Bacillus subtilis submerged fermentation. Be suitable for biological pharmacy, starch sugar, alcohol, beer, monosodium glutamate, fermentation industry, fruit juice, textile, paper-making and so on. Applications: Alcohol, beer. Group: Enzymes. Synonyms: Mid-temperature Refining Alpha-Amylase; for beer; beer; Alpha-Amylase; Mid-temperature Alpha-Amylase; Beer Industry Enzyme; Alpha-Amylase; Mid-temperature Refining Alpha-Amylase for beer; BER-1513. CAS No. 9000-90-2. α-Amylase. Appearance: liqud. Source: Bacillus subtilis. High-temperature Alpha-amylase; beer;High-temperature a-amylase ;a-amylase; EC 3.2.1.1; FOOD HTAA 3211; Alpha-amylase?Glycogenase; bacillus licheniformis; Beer enzyme; liquefaction; incision enzyme; paste starch; High-temperature Alpha-amylase for beer; BER-1511. Pack: 25kg/barrel or subject to client requirement. Cat No: BER-1513.
Mifamurtide
Mifamurtide is a liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities. It is a derivative of the mycobacterial cell wall component MDP and activates both monocytes and macrophages. It is an immunomodulator with antitumor effects that appear to be mediated via activation of monocytes and macrophages. It has orphan drug status for the treatment of osteosarcoma in the US and EU. Synonyms: Mepact; CGP-19835; CGP 19835; CGP19835; MTP-PE; MTP-cephalin; L-MTP-PE; MLV19835. Grades: >98%. CAS No. 83461-56-7. Molecular formula: C59H109N6O19P. Mole weight: 1237.50.
Mifamurtide
Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE; L-MTP-PE; CGP 19835. CAS No. 83461-56-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13682.
Mifamurtide sodium
Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE sodium; L-MTP-PE sodium; CGP 19835 sodium. CAS No. 90825-43-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13682B.
Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor (TNF) release from macrophages isolated from LPS-treated wild type mice but has no effect on cytokine release from MIF deficient macrophages. Group: Biochemicals. Grades: Highly Purified. CAS No. 478336-92-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
MIF Antagonist IV, RDR 03785 (Macrophage Migration Inhibitory Factor Antagonist IV, 6- (Morpholino (4- (trifluoromethyl) phenyl) methyl) -1, 3-benzodioxol-5-ol)
A cell-permeable morpholino-benzodioxol compound that inhibits MIF tautomerase activity (Ki and IC50 = 0.57 and 2.4uM, respectively) via direct non-covalent MIF interaction ( = 24.5uM). RDR 03758 at 10uM is shown to completely neutralize the overriding effect of 100ng/ml MIF on the inhibition of LPS-stimulated TNF production by dexamethasone in RAW 264.7 marcophage cultures. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. Acts as an allosteric MIF (macrophage migration inhibitory factor) inhibitor. It occupies an interface of MIF trimers, leading to the loss of its tautomerase, receptor binding, and pro-inflammatory activities. An excellent tool to design MIF-directed therapeutics for inflammatory diseases. Group: Biochemicals. Grades: Purified. CAS No. 2610-5-1. Pack Sizes: 1g. US Biological Life Sciences.
A symmetrical bis-(amino, hydroxynaphthalene disulfonate) compound that antagonizes macrophage migration inhibitory factor against receptor binding (IC50=810nM against hMIF and CD74 interaction) and is more potent than ISO-1 in suppressing MIF-induced cytokines and MMP-3 productions in human fibroblasts cultures (IC50= <0.7uM vs>5uM). Unlike MIF Antagonists I-IV, p425 targets an area at the interface of two MIF trimers, distal to the active site. Group: Biochemicals. Grades: Highly Purified. CAS No. 2610-5-1. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
Mifepristone
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C29H35NO2. CAS No. 84371-65-3. Prepack ID 32486034-1g. Molecular Weight 429.59. See USA prepack pricing.
Mifepristone
Mifepristone (RU486) is a progesterone receptor ( PR ) and glucocorticoid receptor ( GR ) antagonist with IC 50 s of 0.2 nM and 2.6 nM in in vitro assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU486; RU 38486. CAS No. 84371-65-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-13683.
Mifepristone
Mifepristone is a progesterone receptor antagonist with partial agonist activity. Abortifacient. Group: Biochemicals. Alternative Names: (11 β,17 β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one; RU-486; RU-38486; Mifegyne; Mifeprex; Mifestone; VGX 410. Grades: Highly Purified. CAS No. 84371-65-3. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C29H35NO2, Molecular Weight: 429.59. US Biological Life Sciences.
Worldwide
Mifepristone-d3
A labeled progesterone receptor antagonist with partial agonist activity. Abortifacient. Group: Biochemicals. Alternative Names: (11 β,17 β)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Mifepristone-d6
2H Labeled Compounds. Alternative Names: (8S,11R,13S)-17-Hydroxy-13-methyl-11-(4-(methylamino)phenyl)-17-(prop-1-yn-1-yl)-6,7,8,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one. CAS No. 1228097-18-4. Molecular formula: C29H29D6NO2. Mole weight: 435.63. Catalog: ACM1228097184.
Mifepristone Impurity 1
Mifepristone Impurity 1 is one of Mifepristone impurities. Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Molecular formula: C22H32O3. Mole weight: 344.49.
Mifepristone Impurity 2
Mifepristone Impurity 2 is one of Mifepristone impurities. Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Synonyms: (8S,13S,14S,17S)-17-Hydroxy-13-methyl-17-(prop-1-yn-1-yl)-4,6,7,8,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one; 17β-Hydroxy-17-(1-propynyl)estra-5(10),9(11)-dien-3-one. Grades: > 98%. CAS No. 10109-53-2. Molecular formula: C21H26O2. Mole weight: 310.43.
Mifepristone Impurity 3
Mifepristone Impurity 3 is one of Mifepristone impurities. Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Synonyms: 17β-Hydroxy-17-(but-2yn-1-yl)-estra-5-(10),9(11)-dien-3-one Cyclic 1,2 Ethanediyl Acetal. Molecular formula: C21H26O3. Mole weight: 326.43.
Mifepristone Impurity 4
Mifepristone Impurity 4 is one of Mifepristone impurities. Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Molecular formula: C23H32O5. Mole weight: 388.50.
Mifepristone Impurity 5
Mifepristone Impurity 5 is one of Mifepristone impurities. Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Molecular formula: C21H28O4. Mole weight: 344.44.
Mifepristone Impurity 6
Mifepristone Impurity 6 is one of Mifepristone impurities. Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Molecular formula: C27H33NO3. Mole weight: 419.55.
Mifepristone Impurity 7
Mifepristone Impurity 7 is one of Mifepristone impurities. Mifepristone is a progesterone receptor antagonist with partial agonist activity. It is an abortifacient. Molecular formula: C29H35NO2. Mole weight: 429.59.
Mifepristone related compound
4,5-Dihydro-5α-hydroxy-Mifepristone 3-ethylene Ketal is an impurity of Mifepristone which is a progesterone receptor antagonist with partial agonist activity. Synonyms: 4,5-Dihydro-5α-hydroxy-Mifepristone 3-ethylene Ketal. Grades: > 95%. CAS No. 84371-64-2. Molecular formula: C31H41NO4. Mole weight: 491.66.
Mifepristone (RU-486, RU-38486, Mifegyne,)
A progesterone Receptor antagonist with partial agonist activity. Group: Biochemicals. Alternative Names: RU-486, RU-38486, Mifegyne. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Mifepristone (Standard)
Mifepristone (Standard) is the analytical standard of Mifepristone. This product is intended for research and analytical applications. Mifepristone (RU486) is a progesterone receptor ( PR ) and glucocorticoid receptor ( GR ) antagonist with IC 50 s of 0.2 nM and 2.6 nM in in vitro assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU486 (Standard); RU 38486 (Standard). CAS No. 84371-65-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-13683R.
Migalastat HCl
Migalastat HCl, also known as AT1001 or GR181413A, is a pharmacological chaperone that selectively binds, stabilizes, and increases cellular levels of α-Gal A. Oral administration of migalastat HCl reduces tissue GL-3 in Fabry transgenic mice, and in urine and kidneys of some FD patients. Migalastat HCl may provide a potential novel genotype-specific treatment for Fabry Disease (FD). Phase 3 studies are ongoing. Fabry disease (FD) is a genetic disorder resulting from deficiency of the lysosomal enzyme α-galactosidase A (α-Gal A) which leads to globotriaosylceramide (GL-3) accumulation in multiple tissues. Synonyms: 1,5-Dideoxy-1,5-imino-D-galactitol HCl; DGJ; (2R,3S,4R,5S)-2-methylolpiperidine-3,4,5-triol hydrochloride; Migalastat hydrochloride; Amigal. Grades: 98%. CAS No. 75172-81-5. Molecular formula: C6H13NO4.HCl. Mole weight: 199.63.
Migalastat hydrochloride
Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC 50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR181413A. CAS No. 75172-81-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-14929A.