A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Mexiletine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149961-12-6. Molecular Formula: C11H18ClNO2. Mole Weight: 231.72. Catalog: APB149961126.
Mexiletine Impurity 18
Mexiletine Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 26583-69-7. Molecular Formula: C11H16O2. Mole Weight: 180.25. Catalog: APB26583697.
Mexiletine Impurity 19
Mexiletine Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 68164-73-8. Molecular Formula: C18H24O4S. Mole Weight: 334.43. Catalog: APB68164738.
Mexiletine Impurity 2
Mexiletine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 29238-40-2. Molecular Formula: C11H18ClNO. Mole Weight: 215.72. Catalog: APB29238402.
Mexiletine Impurity 21
Mexiletine Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329835-60-0. Molecular Formula: C11H12D6ClNO. Mole Weight: 221.76. Catalog: APB1329835600.
Mexiletine Impurity 3
Mexiletine Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 55304-19-3. Molecular Formula: C11H15NO2. Mole Weight: 193.25. Catalog: APB55304193.
Mexiletine Impurity 4
Mexiletine Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2415-09-0. Molecular Formula: C8H10O2. Mole Weight: 138.17. Catalog: APB2415090.
Mexiletine Impurity 6
Mexiletine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 180966-61-4. Molecular Formula: C11H17NO. Mole Weight: 179.26. Catalog: APB180966614.
Mexilitine
Mexiletine is a non-selective voltage-gated sodium channel blocker used to treat arrhythmias within the heart, or seriously irregular heartbeats. Uses: Used to treat arrhythmias within the heart, or seriously irregular heartbeats. Synonyms: Mexiletine, Mexitil, Mexiletene, KO-1173, KO 1173, KO1173; 1-(2,6-dimethylphenoxy)-2-propanamin; 1-methyl-2-(2,6-xylyloxy)-ethylamin; 1-Methyl-2-(2,6-xylyloxy)ethylamine; 2-Propanamine, 1-(2,6-dimethylphenoxy)-; Ethylamine, 1-methyl-2-(2,6-xylyloxy)-. Grades: ≥98%. CAS No. 31828-71-4. Molecular formula: C11H17NO. Mole weight: 179.26.
Mexobamol impurity 1
Mexobamol impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10488-39-8. Molecular Formula: C11H15NO5. Mole Weight: 241.24. Catalog: APB10488398.
Mexobamol impurity 2
Mexobamol impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2049-21-0. Molecular Formula: C11H12O5. Mole Weight: 224.21. Catalog: APB2049210.
Mexobamol impurity 3
Mexobamol impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329610-40-3. Molecular Formula: C11H15NO8S. Mole Weight: 321.3. Catalog: APB1329610403.
Mezagitamab
Mezagitamab (TAK-079) is a IgG1λ anti- CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TAK-079. CAS No. 2227490-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99730.
Mezigdomide
Mezigdomide is a new type of protein degrading agent, a cereblon E3 ubiquitin ligase modulating drug, with potential immunomodulatory and anti-tumor activity. Synonyms: CC-92480; CC 92480; CC92480. Grades: >98% by HPLC. CAS No. 2259648-80-9. Molecular formula: C32H30FN5O4. Mole weight: 567.6.
Mezigdomide
Mezigdomide (CC-92480), a cereblon E3 ubiquitin ligase modulating agent (CELMoD), acts as a molecular glue. Mezigdomide shows high affinity to cereblon, resulting in potent antimyeloma activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-92480. CAS No. 2259648-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129395.
Mezlocillin
Mezlocillin. Group: Biochemicals. Grades: Highly Purified. CAS No. 51481-65-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
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Mezlocillin
Mezlocillin is a broad-spectrum, beta-lactam penicillin antibiotic with antibacterial activity. It belongs semisynthetic ampicillin-derived acylureido penicillin. It is active against both Gram-negative and some Gram-positive bacteria. It inhibits the third and last stage of bacterial cell wall synthesis by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections. It is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. Uses: Mezlocillin has antibacterial activity. it is active against both gram-negative and some gram-positive bacteria. it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. Synonyms: BAY-f 1353; 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid; [2S- [2α , 5α , 6β (S*) ] ] -3, 3-Dimethyl-6- [ [ [ [ [3- (methylsulfonyl) -2-oxo-1-imidazolidinyl] carbonyl] amino] phenylacetyl] amino] -7-oxo-4-thia-1-azabicyclo [3. 2. 0] heptane-2-carboxylic Acid; Mezlin; Mezlocillinum; Mezlocilina; Mezlocilline. Grades: ≥98%. CAS No. 51481-65-3. Molecular formula: C21H25N5O8S2. Mole weight: 539.58.
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H24N5NaO8S2. CAS No. 59798-30-0. Prepack ID 77075760-100mg. Molecular Weight 561.56. See USA prepack pricing.
Mezlocillin sodium
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-f 1353 sodium. CAS No. 42057-22-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1466.
Mezlocillin Sodium
Mezlocillin Sodium. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
MF498
MF498 is a novel and selective E prostanoid receptor 4 (EP4 receptor) antagonist, a Gs protein-coupled receptor, with Ki of 0.7 nM. It plays important roles in bone formation and resorption, inflammation, cancer, and atherosclerosis. It has been shown to inhibit inflammation without gastrointestinal toxicity in various animal models for arthritis. It also displays a relatively good selectivity over other prostanoid receptors. It does not compromise the mucosal integrity in the gastrointestinal tract in vitro. It inhibits PGE2-stimulated cAMP accumulation in a dose-dependent manner. It relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis in vivo. Uses: Mf498 plays important roles in bone formation and resorption, inflammation, cancer, and atherosclerosis. it has been shown to inhibit inflammation without gastrointestinal toxicity in various animal models for arthritis. it relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis in vivo. Synonyms: MF498; MF 498; MF-498; C 528911; C-528911; C528911; N-[[[4-(5,9-Diethoxy-6,8-dihydro-6-oxo-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methyl]sulfonyl]-2-methoxy-benzeneacetamide;N-[[4-(5,9-diethoxy-6-oxo-8H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylphenyl]methylsulfonyl]-2-(2-methoxyphenyl)acetamide. Grades: >98%. CAS No. 915191-42-3. Molecular formula: C32H33N3O7S. Mole weight: 603.69.
MF592
MF592 is a potent and selective antagonists of the EP4 receptor. It has good functional potency and potent inhibition of PGE2 modulated TNFa release in LPS stimulated human whole blood (hWB). It displays an excellent oral pharmacokinetic (PK) profile and in vivo efficacy in a rat chronic adjuvant-induced-arthritis model. It has a desirable overall preclinical profile that suggests it is suitable for further development. Synonyms: MF-592; MF 592; MF592; 2, 6-Dichloro-N- ( (1- (4- (4, 9-diethoxy-1-oxo-1, 3-dihydro-2H-benzo[f]isoindol-2-yl) -3-methylbenzyl) cyclopropyl) carbamoyl) benzenesulfonamide. Grades: >98%. CAS No. 1064195-48-7. Molecular formula: C34H33Cl2N3O6S. Mole weight: 682.61.
Mf-63
Mf-63 is a selective Microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. Its IC50 value is 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively. It displays greater than 1,000-fold selectivity over other prostanoid synthases. It strongly inhibited guinea pig mPGES-1 but not the mouse or rat enzyme in rodent species. It did not cause NSAID-like gastrointestinal toxic effects that is caused by non-selective COX inhibitors, although it markedly suppresses PGE2 synthesis in the stomach. It prevents LPS-induced hyperglasia. It has anti-inflammatory, analgesic and anti-cancer agent. Uses: Mf-63 has anti-inflammatory, analgesic and anti-cancer agent. Synonyms: 2-(9-Chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-1,3-benzenedicarbonitrile;2-(6-chloro-1H-phenanthro-[9,10-d]iMidazol-2-yl)isophthalonitrile;MF-63; MF63; MF 63. Grades: >98%. CAS No. 892549-43-8. Molecular formula: C23H11ClN4. Mole weight: 378.81.
Mfa-hst5
Mfa-hst5 is from Macaca fascicularis and has antifungal, Candida spp. and Criptococcus spp. activities.
MF-EA-705alpha
It is originally isolated from Streptomyces sp. MF-EA-705. And the MIC of MF-EA-705alpha against Candida albicans was 1 g/mL. Molecular formula: C20H22O2. Mole weight: 294.39.
MF-EA-705beta
MF-EA-705beta is an antifungal antibiotic isolated from Streptomyces sp. MF-EA-705. Synonyms: (3E,5E,7Z)-8-{2-[(1Z)-but-1-en-1-yl]-4-methylphenyl}nona-3,5,7-trienoic acid. Molecular formula: C20H24O2. Mole weight: 294.39.
Mfe I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑AATTG GTTAA↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Mfe I from Mycoplasma fermentans. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1131RE.
m-Fluoro Prasugrel Thiolactone (Mixture of Diastereomers)
An Intermediate in the synthesis of m-Fluoro Prasugrel. Synonyms: 5-[2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: > 95%. CAS No. 1618107-97-3. Molecular formula: C18H18FNO2S. Mole weight: 331.41.
m-Fluoro Prasugrel Thiolactone. (Mixture of Diastereomers)
Intermediate in the synthesis of m-Fluoro Prasugrel (F595870). Group: Biochemicals. Alternative Names: 5-[2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
MFZ 10-7
MFZ 10-7. Group: Biochemicals. Grades: Purified. CAS No. 1224431-15-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MFZ 10-7
MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a K i of 0.67 nM for rat mGluR5 [1]. MFZ 10-7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1224431-15-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103575.
MFZ 10-7
MFZ 10-7 is a mGlu5 receptor negative allosteric modulator. It can inhibit mGlu5 glutamate-mediated calcium mobilization with IC50 value of 1.22 nM. MFZ 10-7 can inhibit cocaine-taking and cocaine-seeking behavior in rats. Synonyms: 3-Fluoro-5-[2-(6-methyl-2-pyridinyl)ethynyl]benzonitrile hydrochloride. Grades: ≥99% by HPLC. CAS No. 1224431-15-5. Molecular formula: C15H9FN2.HCl. Mole weight: 272.7.
MG 101. Group: Biochemicals. Grades: Purified. CAS No. 110044-82-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
MG-101
MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K i s of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain inhibitor I; Ac-LLnL-CHO; ALLN. CAS No. 110044-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18964.
A potent, reversible proteasome inhibitor with Ki of 21nM for 20S proteasome and 35nM for 26S proteasome. The inhibition of proteasome was through specific inhibition of chymotrypsin-like activity of the proteasome. Also shown to induce apoptosis in Rat-1 and PC12 cells via a p3-independent pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MG-132
MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC 50 s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Leu-Leu-Leu-al; MG132. CAS No. 133407-82-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13259.
MG-132 is a potent Proteasome inhibitor with potential anticancer activity. MG-132 induces MCPIP1 expression; induces C6 glioma cell apoptosis via oxidative stress; induces AIF nuclear translocation through down-regulation of ERK and Akt/mTOR pathway. Synonyms: Z-Leu-leu-leu-al. CAS No. 133407-82-6. Molecular formula: C26H41N3O5. Mole weight: 475.62.
MG-132 (Z-Leu-Leu-Leu-CHO)
Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kB activation inhibitor through IκB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin inhibitor. Has anticancer properties by inducing cell cycle arrest and activating apoptosis in various cancer cell lines. Has adjuvant / chemosensitizer potential. Neurite outgrowth stimulator in PC12 cells. Prevents beta-secretase cleavage. Autophagy activator. Group: Biochemicals. Alternative Names: Z-Leu-Leu-Leu-al; Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal; Proteasome Inhibitor XI). Grades: Highly Purified. CAS No. 133407-82-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C26H41N3O5, Sequence: Z-Leu-Leu-Leu-aldeyhde. US Biological Life Sciences.
Worldwide
MG149
MG149 is a potent histone acetyltransferase inhibitor with IC50 of 74 μM and 47 μM for Tip60 and MOF,respectively. Synonyms: MG149; MG 149; MG-149. Grades: >98%. CAS No. 1243583-85-8. Molecular formula: C22H28O3. Mole weight: 340.46.
MG 149
MG 149. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1243583-85-8. Molecular Formula: C22H28O3. Mole Weight: 340.46. Catalog: APB1243583858.
Mg2+-importing ATPase
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme occurs in both Gram-positive and Gram-negative bacteria, and three types are known, designated as CorA, MgtA and MgtB. The CorA itself is not an ATPase but an Mg2+ transporter. Group: Enzymes. Enzyme Commission Number: EC 3.6.3.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4656; Mg2+-importing ATPase; EC 3.6.3.2. Cat No: EXWM-4656.
MG 624
MG624 is a neuronal nicotinic acetylcholine receptors antagonist. It is selective for neuronal nAChRs over muscle-type AChRs. It can decrease vagus nerve stimulation-induced contractions of isolated guinea pig vagus nerve-stomach preparations. Synonyms: MG624; MG 624; MG-624; N,N,N-Triethyl-2-[4-(2-phenylethenyl)phenoxy]ethanaminium iodide. Grades: ≥98% by HPLC. CAS No. 77257-42-2. Molecular formula: C22H30NOI. Mole weight: 451.39.
MG 624
MG 624. Group: Biochemicals. Grades: Purified. CAS No. 77257-42-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MGA271
Enoblituzumab is a monoclonal antibody designed for the treatment of cancer. Formerly known as MGA271, the drug is a humanized IgG1κ monoclonal antibody recognizing human. B7-H3, a member of the B7 family of immune regulators. Synonyms: MGA271; MGA 271; MGA-271; Enoblituzumab; UNII-M6030H73N9. CAS No. 1353485-38-7. Molecular formula: C6474H9990N1726O2030S42.
MGA-C13
This glucoside shows remarkable behavior for the stabilization of a variety of membrane proteins including transporters and GPCRs. The presence of glucoside head group is beneficial to the formation of small complexes with membrane proteins and the formation of high quality protein crystal and clear visualization via CryoEM. Synonyms: Mesitylene-cored glucoside amphiphile-C13. Grades: >99%. CAS No. 2102603-26-7. Molecular formula: C93H168O36. Mole weight: 1862.34.
MGA-C13
Non-ionic Detergents. Alternative Names: Mesitylene-cored glucoside amphiphile-C13. CAS No. 2102603-26-7. Molecular formula: C93H168O36. Mole weight: 1862.33. Appearance: Powder. Purity: >99%.
MGAT2-IN-1
An orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) (IC50= 7.8 for human, and 2.4 nM for mouse MGAT2). Synonyms: N-(4-chloro-2,6-difluorophenyl)-1-[5-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]pyrimidin-2-yl]-7-(2-oxopyrrolidin-1-yl)-2,3-dihydroindole-5-sulfonamide. CAS No. 1800025-30-2. Molecular formula: C27H21ClF5N7O3S. Mole weight: 654.01.
MGAT5 (intro)
The MGAT5 gene encodes mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides.
MGB-BP-3
MGB-BP-3 is an antibiotic that has been shown to be active against a broad range of important multi-resistant Gram-positive pathogens. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000277-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00035.
MGB Eclipse® CPG
MGCD-265
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively and also inhibits Ron and Tie2. Synonyms: MGCD-265; MGCD 265; MGCD265; MGCD-265-analog; MGCD 265-analog; MGCD265-analog. Glesatinib-analog. Grades: >98%. CAS No. 875337-44-3. Molecular formula: C26H20FN5O2S2. Mole weight: 517.60.
MGCD-265
MGCD-265. Group: Biochemicals. Alternative Names: N- [ [ [3-Fluoro-4- [ [2- (1-methyl-1H-imidazol-4-yl) thieno [3, 2-b] pyridin-7-yl] oxy] phenyl] amino] thioxomethyl] -benzeneacetamide. Grades: Highly Purified. CAS No. 875337-44-3. Pack Sizes: 5mg. Molecular Formula: C26H20FN5O2S2, Molecular Weight: 517.6. US Biological Life Sciences.
Worldwide
MGCD-265 analog
MGCD-265 analog is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC 50 s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875337-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10991.
MGF
Mechano growth factor (MGF) is a spliced variant of insulin-like growth factor 1 (IGF-1). IGF-1 is found in various tissues in the body including liver and muscle. Synonyms: MGF E-domain; IGF-1 EC; Mechano Growth Factor. Grades: 98%. Molecular formula: C121H199N40O40. Mole weight: 2868.19.
MgK-264 (N-octylbicycloheptenedicarboximide) is a synergist enhancing the potency of pyrethroid ingredients. MgK-264 has no intrinsic pesticidal qualities itself [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Octylbicycloheptenedicarboximide; ENT 8184. CAS No. 113-48-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W013170.
MGL-3196
MGL-3196 is a first-in-class, orally available, once-daily and liver-directed thyroid hormone receptor (THR) beta-selective agonist. Studies suggest that MGL-3196 has an attractive, differentiated profile as a potential treatment for non-alcoholic steatohepatitis (NASH) and dyslipidemias. Uses: Potential treatment for non-alcoholic steatohepatitis (nash) and dyslipidemias. Synonyms: CHEMBL3261331; UNII-RE0V0T1ES0; MGL-3196; MGL 3196; MGL3196; VIA 3196; VIA3196; VIA-3196; Resmetirom.RE0V0T1ES0; 2-[3,5-dichloro-4-[(6-oxo-5-propan-2-yl-1H-pyridazin-3-yl)oxy]phenyl]-3,5-dioxo-1,2,4-triazine-6-carbonitrile. CAS No. 920509-32-6. Molecular formula: C17H12Cl2N6O4. Mole weight: 435.211.
Mgnesium Chloride 7791-18-6
Mgnesium Chloride - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
MH-031 is produced by the strain of Streptomyces rishiriensis A-5969 with protective effects on the liver. Synonyms: 3-(2-Oxo-2,5-dihydro-3-furanyl)propanoic acid; ACMC-20mpyj. CAS No. 122246-01-9. Molecular formula: C7H8O4. Mole weight: 156.14.
Mhl I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. GDGCH↑C C↓HCGDG. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Micrococcus halobius SD. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1132RE.
MHP
MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase ( SPHK1 ), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methyl caprooyl tyrosinate. CAS No. 1104874-94-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101572.
MHY1485
mTOR activator with an inhibitory effect on autophagy. MHY1485 markedly increased the LC3II/LC3I ratio dose-dependently and time-dependently by inhibition of the fusion between autophagosomes and lysosomes, and without increasing the autophagic flux. At 2 μM, MHY1485 did not show any cell death during longer treatment, supporting that MHY1485 had less toxicity than other well-known inhibitors of autophagy. MHY1485 was also tested and found moderately active as antimalarial agent (MIC value of ca. 26 μM against P. Falciparum). Synonyms: MHY-1485; MHY1485; MHY 1485. Grades: >98%. CAS No. 326914-06-1. Molecular formula: C17H21N7O4. Mole weight: 387.39.
MHY219
MHY219 is a novel HDAC inhibitor. MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells. MHY219 was shown to enhance the cytotoxicity on DU145 cells (IC50, 0.36 μM) when compared with LNCaP (IC50, 0.97 μM) and PC3 cells (IC50, 5.12 μM). MHY219 showed a potent inhibition of total HDAC activity when compared with SAHA. MHY219 increased histone H3 hyperacetylation and reduced the expression of class I HDACs (1, 2 and 3) in prostate cancer cells. MHY219 effectively increased the sub-G1 fraction of cells through p21 and p27 dependent pathways in DU145 cells. MHY219 significantly induced a G2/M phase arrest in DU145 and PC3 cells and arrested the cell cycle at G0/G1 phase in LNCaP cells. Furthermore, MHY219 effectively increased apoptosis in DU145 and LNCaP cells, but not PC3 cells, according to Annexin V/PI staining and Western blot analysis. These results indicate that MHY219 is a potent HDAC inhibitor that targets regulating multiple aspects of cancer cell death and might have preclinical value in human prostate cancer chemotherapy, warranting further investigation. Synonyms: MHY219; MHY-219; MHY 219. Grades: 98%. CAS No. 1326750-61-1. Molecular formula: C20H25N3O3. Mole weight: 355.43.