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| Product | Description | |
|---|---|---|
| ML 230 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| ML 236A | It has the activity of inhibiting HMG-CoA reductase, and it is produced by the strain of Penicillum citrinum SANK. Synonyms: Compactin diol lactone; ML-236A; 6-(2-(1,2,6,7,8,8a-Hexahydro-8-hydroxy-2-methyl-1-naphthalenyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one; desmethylmonacolin J; Antibiotic ML 236A. CAS No. 58889-19-3. Molecular formula: C18H26O4. Mole weight: 306.40. |  |
| ML239 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML240 | ML240 is a potent p97 inhibitor, inhibiting p97 ATPase with IC 50 value of 100 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346527-98-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19795. |  |
| ML240 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 240 | ML 240. Group: Biochemicals. Grades: Purified. CAS No. 1346527-98-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ML241 | ML241 is a potent, selective and competitive p97 ATPase inhibitor with an IC50 of 0.11 ?M. ML241 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346528-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19797. | |
| ML243 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML243 (Cancer Stem Cell Inhibitor, ML243, (E) -N- (4, 5-Dihydrothiazol-2-yl) -3- (4-ethylphenyl) acrylamide, (2E)-N-(4,5-Dihydro-1,3-thiazol-2-yl)-3-(4-ethylphenyl)prop-2-enamide) | A cell-permeable, biologically stable, 4-ethyl substituted cinnamide analog that selectively exerts an inhibitory effect on breast cancer stem-like cells (EC50 = 2uM for epithelial-to-mesenchymal transition; HMLE_shEcad). Exhibits ~32-fold greater selectivity over isogenic control cells (EC50 = 64uM; HMLE cell line expressing shRNA against eGFPcells; HMLE_sh_eGFP). Displays desirable aqueous solubility (~11.5uM in PBS, pH 7.4) and excellent stability in human plasma and in glutathione solution. Shown to block the binding to a radio-labeled ligand to the Adenosine A2A Receptor (IC50 = 10uM), but does not affect 68 other targets studied. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| ML252 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML254 | ML254 is a potent mGlu 5 potentiator, with EC 50 and pEC 50 of 9.3 nM and 8.03 nM for rat mGlu 5 , respectively. ML254 can be used for researching schizophrenia [1]. ML254 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1428630-86-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16654. | |
| ML261 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML264 | ML264 is an antitumor agent that potently and selectively inhibits Krüppel-like factor five ( KLF5 ) expression. Uses: Scientific research. Group: Signaling pathways. CAS No. 1550008-55-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19994. | |
| ML264 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML277 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML277 | ML277 (CID-53347902) is a potent and selective activator of K(V)7.1 (KCNQ1) potassium channel activator (EC50=270 nM), rescues function of pathophysiologically important mutant channel complexes in human induced pluripotent stem cell-derived cardiomyocytes[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CID-53347902. CAS No. 1401242-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12343. | |
| ML 277 | ML 277. Group: Biochemicals. Grades: Purified. CAS No. 1401242-74-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML 281 | ML 281. Group: Biochemicals. Grades: Purified. CAS No. 1404437-62-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML289 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 289 | ML 289. Group: Biochemicals. Grades: Purified. CAS No. 1382481-79-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML-290 | ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1]. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1482500-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112606. | |
| ML291 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML297 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 297 | ML 297 (VU 0456810) is a potent and selective GIRK 1/2 activator, with an EC 50 of 0.16 μM. ML 297 is potential for the treatment of epilepsy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VU 0456810; CID 56642816. CAS No. 1443246-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110192. | |
| ML 297 | ML 297. Group: Biochemicals. Grades: Highly Purified. CAS No. 1443246-62-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML298 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 298 hydrochloride | ML 298 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML303 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML309 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML314 maleate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 315 hydrochloride | ML 315 is a selective dual inhibitor of CDK and DYRK with IC 50 s of 68 nM and 282 nM, respectively. ML 315 is used in cancer and neurological disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2172559-91-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-117608A. | |
| ML318 | ML318 is a novel inhibitor of Pseudomonas aeruginosa PvdQ acylase, an enzyme involved in siderophore pyoverdine synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1610516-67-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H8F4N2, Molecular Weight: 280.22. US Biological Life Sciences. | Worldwide |
| ML318 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML323 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML-323 | ML-323 is a reversible, potent USP1-UAF1 inhibitor with IC50 of 76 nM in a Ub-Rho assay. The measured inhibition constants of ML-323 for the free enzyme (Ki) is 68 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1572414-83-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17543. | |
| ML324 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML324 | ML324 is a potent JMJD2 demethylase inhibitor with antiviral activity. ML324 also exhibits inhibition for the histone demethylase KDM4B, with an IC50 of 4.9 ?M. ML324 has potent anti-viral activity against both herpes simplex virus (HSV) and human cytomegalovirus (hCMV) infection via inhibition viral IE gene expression[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1222800-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12725. | |
| ML329 | ML329 is a micropthalmia-associated transcription factor (MITF) inhibitor, which inhibits TRPM-1 promoter activity with an IC50 of 1.2 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 19992-50-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101464. | |
| ML334 | ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 ?M. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LH601A. CAS No. 1432500-66-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110258. | |
| ML336 | ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613465-33-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-12928. | |
| ML 337 | ML 337. Group: Biochemicals. Grades: Purified. CAS No. 1443118-44-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML338 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML339 | ML339 is a selective CXCR6 antagonist with an IC50 of 140 nM. ML339 antagonizes ?-arrestin recruitment and cAMP signaling pathway of human CXCR6 receptor induced by CXCL16, with IC50 of 0.3 ?M and 1.4 ?M, respectively. ML339 shows weaker activity against the recruitment of ?-arrestin in mouse CXCR6 receptors, with an IC50 of 18 ?M. ML339 has no inhibitory effect on CXCR5?CXCR4?CXCR6 and apelin receptor (APJ), with IC50 >79 ?M. ML339 has the potential to promote the development of prostate cancer research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2579689-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122197. | |
| ML-339 | ML-339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ML-339; ML 339; ML339. Product Category: Antagonists. Appearance: Solid powder. CAS No. 2579689-83-9. Molecular formula: C26H32ClN3O5. Mole weight: 502.01. Purity: >98%. IUPACName: N-((1R,3s,5S)-9-(2-((2-chlorophenyl)amino)-2-oxoethyl)-9-azabicyclo[3.3.1]nonan-3-yl)-3,4,5-trimethoxybenzamide. Canonical SMILES: O=C(N[C@@H]1C[C@H](N2CC(NC3=CC=CC=C3Cl)=O)CCC[C@H]2C1)C4=CC(OC)=C(OC)C(OC)=C4. Product ID: ACM2579689839. Alfa Chemistry ISO 9001:2015 Certified. Categories: MD 339. |  |
| ML 3403 | ML 3403. Group: Biochemicals. Grades: Purified. CAS No. 549505-65-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML346 | ML346 is an activator of Hsp70 expression and HSF-1 activity, with an EC50 of 4.6 ?M for Hsp70. ML346 restores protein folding in conformational disease models, without significant cytotoxicity or lack of specificity. ML346 induces specific increases in genes and protein effectors of the heat shock response (HSR), including chaperones such as Hsp70, Hsp40, and Hsp27[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100872-83-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18669. | |
| ML347 | ML347 (LDN193719) is a highly selective ALK1/ALK2 inhibitor. ML347 has IC50 values of 46 and 32 nM against ALK1 and ALK2, respectively, >300-fold selective over ALK3. ML347 block the phosphorylation of Smad1/5 by TGF-?1[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LDN 193719. CAS No. 1062368-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12274. | |
| ML347 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 347 | ML 347. Group: Biochemicals. Grades: Purified. CAS No. 1062368-49-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML348 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML348 | ML348 (GNF-Pf-1127) is a selective and reversible acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM, and barely inhibits LYPLA2[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GNF-Pf-1127. CAS No. 899713-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100736. | |
| ML 348 | ML 348. Group: Biochemicals. Grades: Purified. CAS No. 899713-86-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML349 | ML349 is a potent and specific acyl protein thioesterase 2(APT2)/lysophospholipase 2 (LYPLA2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890819-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100737. | |
| ML349 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 349 | ML 349. Group: Biochemicals. Grades: Purified. CAS No. 890819-86-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML351 | ML351 is a potent and highly specific 15-LOX-1 inhibitor with an IC 50 of 200 nM. ML351 shows excellent selectivity (>250-fold) versus the related isozymes, 5-LOX, platelet 12-LOX, 15-LOX-2, ovine COX-1, and human COX-2 [1]. ML351 prevents dysglycemia and reduces β-cell oxidative stress in nonobese diabetic mouse model of T1D [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 847163-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111310. | |
| ML351 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML354 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML 354 | ML 354. Group: Biochemicals. Grades: Purified. CAS No. 89159-60-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML355 | ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 ?M, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties. Uses: Scientific research. Group: Signaling pathways. CAS No. 1532593-30-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12341. | |
| ML364 | ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 ?M) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 ?M), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1991986-30-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-100900. | |
| ML364 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML385 | ML385 Inhibitor. Uses: Scientific use. Product Category: T4360. CAS No. 846557-71-9. |  |
| ML385 | ML385 is a specific nuclear factor erythroid 2-related factor 2 (NRF2) inhibitor with an IC50 of 1.9 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 846557-71-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100523. | |
| ML385 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML390 | ML390 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor. ML390 is an inducer of myeloid differentiation and causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) acute myeloid leukemia (AML) models[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2029049-79-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100688. | |
| ML396 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML402 | ML402, a thiophene-carboxamide, is a selective K2P2.1(TREK-1) and K2P10.1(TREK-2) activator. ML402 is inactive against K2P4.1(TRAAK)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 298684-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104027. | |
| ML406 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| ML-60218 | ML-60218 is a broad-spectrum RNA pol III inhibitor, with IC50s of 32 and 27 ?M for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and to hamper the formation of new ones without the need for de novo transcription of cellular RNAs[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 577784-91-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122122. | |
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