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| Product | Description | |
|---|---|---|
| Mivacurium Chloride Impurity 13 | Mivacurium Chloride Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,1'R,2R,2'R)-2,2'-((((E)-oct-4-enedioyl)bis(oxy))bis(propane-3,1-diyl))bis(6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium) chloride. CAS No. 107740-65-8. Molecular formula: C58H80N2O14·2Cl. Mole weight: 1098.5. Catalog: APB107740658. |  |
| Mivacurium Chloride Impurity 21 | Mivacurium Chloride Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026602-92-5. Molecular formula: C6H13ClO2. Mole weight: 152.62. Catalog: APB1026602925. | |
| Mivacurium Chloride Impurity 23 | Mivacurium Chloride Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104758-47-6. Molecular formula: C22H29NO5. Mole weight: 387.48. Catalog: APB104758476. | |
| Mivacurium Chloride Impurity A | Mivacurium Chloride Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2S)-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. CAS No. 107740-66-9. Molecular formula: C25H36NO6·Cl. Mole weight: 482.01. Catalog: APB107740669. | |
| Mivacurium Chloride Impurity B | Mivacurium Chloride Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R)-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. CAS No. 107740-64-7. Molecular formula: C25H36NO6·Cl. Mole weight: 482.01. Catalog: APB107740647. | |
| Mivacurium Chloride (mixture of isomers) | Non-depolarizing neuromuscular blocking agent. Muscle relaxant (skeletal). Group: Biochemicals. Alternative Names: (1R, 1'R) -2, 2'-[[ (4E) -1, 8-Dioxo-4-octene-1, 8-diyl]bis (oxy-3, 1-propanediyl) ]bis[1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-methyl-1-[ (3, 4, 5-trimethoxyphenyl) methyl]-isoquinolinium Chloride ; Mivacron; BW-B 1090U. Grades: Highly Purified. CAS No. 106861-44-3. Pack Sizes: 2.5mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??Cl?N?O??, Molecular Weight: 1100.17. US Biological Life Sciences. |  Worldwide |
| Mivacurium dichloride | Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106861-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1700A. |  |
| Mivebresib | Mivebresib (ABBV-075) is a potent and orally active bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a K i of 1.5 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABBV-075. CAS No. 1445993-26-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100015. | |
| Mix Coal Tar/Petroleum Extract in Methylene Chloride | Mix Coal Tar/Petroleum Extract in Methylene Chloride. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS009969. Shipping: Room Temperature. | |
| Mixed amino resin | Mixed amino resin. Group: Polymers. |  |
| Mixed tocopherol microencapsulated powder | Mixed tocopherol microencapsulated powder. Product ID: CDF4-0195. Molecular formula: NA. Category: Antioxidant; nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0195; Mixed tocopherol microencapsulated powder; Antioxidant; nutrient supplements. Appearance: light yellow powder. Color: light yellow. Physical State: powder. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc. |  |
| Mixed Tocopherols | Mixed Tocopherols. CAS No: 1406-18-4 |  Sarchem Laboratories New Jersey NJ |
| Mixed vegetables (vitamins) | certified Reference Material. Group: Certified reference materials (crms). | |
| Mixoxantrone HCI | Mixoxantrone HCI. Group: Biochemicals. Grades: Highly Purified. CAS No. 70476-82-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C22H28N4O6HCI. US Biological Life Sciences. | Worldwide |
| Mixture of 1,2,3-Propanetriol 2-(Dihydrogen phosphate) Sodium Salt Hydrate and 1,2,3-Propanetriol 1-(Dihydrogen phosphate) Sodium Salt Hydrate | 1,2,3-Propanetriol 2-(Dihydrogen phosphate) is a serine-threonine phosphatase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g, 10g. Molecular Formula: C3H7Na2O6P xH2O. US Biological Life Sciences. | Worldwide |
| Mixture of (R)-Apomorphine-11-sulfate Potassium Salt-d5 + (R)-Apomorphine-10-sulfate. (d4-Major) (90%) | (R)-Apomorphine-11-sulfate Potassium Salt-d5 is the isotope labelled analog of (R)-Apomorphine-11-sulfate Potassium Salt (A727520); a derivative of (R)-Apomorphine (A727500) which is a dopamine (D1 and D2) receptor agonist, emetic, and antiparkinsonian. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C17H11D5KNO5S. US Biological Life Sciences. | Worldwide |
| Miyakamide A1 | Miyakamide A1 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide A1 inhibits the growth of Artemia salina at a minimum concentration of 5 μg/mL. Miyakamide A1 has weak antixanthomonas activity. It inhibits P388 cells with an IC50 of 10.5 μg/mL. CAS No. 497252-38-7. Molecular formula: C31H32N4O3. Mole weight: 508.61. |  |
| Miyakamide A2 | Miyakamide A2 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide A2 inhibits the growth of Artemia salina at a minimum concentration of 5 μg/mL. Miyakamide A1 has weak antixanthomonas activity. It inhibits P388 cells with an IC50 of 12.2 μg/mL. CAS No. 497252-39-8. Molecular formula: C31H32N4O3. Mole weight: 508.61. | |
| Miyakamide B1 | Miyakamide B1 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide B1 inhibits the growth of Artemia salina at a minimum concentration of 20 μg/mL. It inhibits P388 cells with an IC50 of 8.8 μg/mL. CAS No. 497182-82-8. Molecular formula: C31H32N4O4. Mole weight: 524.61. | |
| Miyakamide B2 | Miyakamide B2 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide B2 inhibits the growth of Artemia salina at a minimum concentration of 20 μg/mL. It inhibits P388 cells with an IC50 of 7.6 μg/mL. CAS No. 497182-83-9. Molecular formula: C31H32N4O4. Mole weight: 524.61. | |
| Mizacorat | Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD9567. CAS No. 1893415-00-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-120012. | |
| Mizagliflozin | Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a K i of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DSP-3235 free base; KGA-3235 free base; GSK-1614235 free base. CAS No. 666843-10-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17638. | |
| Mizolastine | Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165 , VEGF120 , TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108612-45-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0164. | |
| Mizolastine | A highly selective histamine H1-receptor antagonist (with no anticholinergic, antiadrenergic, or antiserotonin activity) for use in the treatment of allergic disorders, especially rhinitis and urticaria. Group: Biochemicals. Alternative Names: 2- [ [1- [1- [ (4-Fluorophenyl) methyl] -1H-benzimidazol-2-yl] -4-piperidinyl] methylamino] - 4(1H)-pyrimidinone; MKC 431; Mistamine; Mizollen; SL 850324; Zolistan. Grades: Highly Purified. CAS No. 108612-45-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Mizolastine | Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. Uses: Histamine h1 antagonists, non-sedating. Synonyms: Mizollen; SL 850324; SL850324; SL-850324; Mistalin; Mistamine; Mizolastina; Mizolastine. Grade: >98%. CAS No. 108612-45-9. Molecular formula: C24H25FN6O. Mole weight: 432.49. | |
| Mizoribine | Mizoribine. Group: Biochemicals. Alternative Names: 1-(b-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide. Grades: Highly Purified. CAS No. 50924-49-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C9H13N3O6. US Biological Life Sciences. | Worldwide |
| Mizoribine | Bredinin is a nucleoside antibiotic produced by Eupenicillum brefeldianum M-2166. It has anti-L-5178Y cell and anti-pox virus activity, not against bacteria and fungi. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: N'-(b-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide; Bredinin; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide; 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide. Grade: ≥95%. CAS No. 50924-49-7. Molecular formula: C9H13N3O6. Mole weight: 259.22. | |
| Mizoribine | Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC 50 of approximately 100 μM for anti-HCV activity. Immunosuppressant [1]. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC 50 s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 289637; HE 69. CAS No. 50924-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17470. | |
| Mizoribine | ?98% (TLC). Group: Fluorescence/luminescence spectroscopy. | |
| MIZORIBINE | MIZORIBINE. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N'-[BETA-D-RIBOFURANOSYL]-5-HYDROXYIMIDAZOLE-4-CARBOXAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 50524-49-7. Molecular formula: C9H13N3O6. Mole weight: 259.22. Purity: 0.96. IUPACName: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide. Canonical SMILES: C1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N. Density: 2.06g/cm³. Product ID: ACM50524497. Alfa Chemistry ISO 9001:2015 Certified. |  |
| MJ33 lithium salt | powder, ?90% (NMR). Group: Fluorescence/luminescence spectroscopy. | |
| MJ347-81F4-B | MJ347-81F4-B is originally isolated from Amycolatopsis sp. MJ347-81F4. It has good anti-gram-positive bacteria activity, including clinically isolated methicillin-resistant Staphylococcus aureus (MIC 0.05-0.2 μg/mL). Molecular formula: C60H58N14O18S5. Mole weight: 1423.51. | |
| MJN110 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MJN110 | MJN110 is an orally active and selective monoacylglycerol lipase (MAGL) inhibitor with IC50s of 9.1 nM and 2.1 nM for hMAGL and 2-arachidonoylglycerol (2-AG), respectively[1]. MJN110 produces opioid-sparing effects and displays strong antihyperalgesic activity[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1438416-21-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117474. | |
| MJN228 | MJN228 is a lipid-binding protein nucleobindin-1 ( NUCB1 ) inhibitor with an IC 50 of 3.3 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 459168-97-9. Pack Sizes: 1 mg. Product ID: HY-118319. | |
| MK-0159 | MK-0159 is an orally active, potent and selective CD38 inhibitor, with IC50 values of 22, 3, and 70 nM for human, mouse and rat CD38, respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD+ (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2641484-61-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150508. | |
| MK 0343 | MK 0343. Group: Biochemicals. Grades: Purified. CAS No. 233275-76-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK-0343 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MK-0429 | MK-0429 (L-000845704) is an orally active, potent, selective and nonpeptide pan-integrin antagonist with IC50 values of 1.6 nM, 2.8 nM, 0.1 nM, 0.7 nM, 0.5 nM and 12.2 nM for ?v?1, ?v?3, ?v?5, ?v?6, ?v?8 and ?5?1, respectively[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-000845704. CAS No. 227963-15-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15102. | |
| MK-0493 | MK-0493 is a potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R) , demonstrating significant reductions in energy intake [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 455956-93-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-118930. | |
| MK-0493 hydrochloride | MK-0493 hydrochloride is a potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R) , demonstrating significant reductions in energy intake [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 455957-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-118930A. | |
| MK 0677 | MK 0677. Group: Biochemicals. Grades: Purified. CAS No. 159752-10-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK-0731 | MK-0731 is a selective, non-competitive and allosteric kinesin spindle protein (KSP) inhibitor with an IC50 of 2.2 nM and a pKa of 7.6. MK-0731 is >20,000 fold selectivity against other kinesins. MK-0731 induces mitotic arrest and induces apoptosis in tumors. MK-0731 provides significant antitumor efficacy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845256-65-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-50672. | |
| Mk-0752 | Mk-0752. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MK-0752, 471905-41-6, MK 0752, 471905-41-6, MK0752, MK 0752, 3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid, cc-14, SureCN756247, SureCN756248, SureCN756249, MK0752, RW3012, BCP9000935, BCP9000936, CS-0253, QC-1905, RL03744, NCGC00263184-01, HY-10974, X7591, L-000891675. Product Category: Heterocyclic Organic Compound. CAS No. 952578-68-6. Molecular formula: C21H21ClF2O4S. Mole weight: 442.903846 [g/mol]. Purity: 0.96. IUPACName: 3-[4-(4-chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]propanoic acid. Canonical SMILES: C1CC(CCC1CCC(=O)O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl. Density: 1.361±0.06 g/cm³ (20 °C, 760 mmHg). Product ID: ACM952578686. Alfa Chemistry ISO 9001:2015 Certified. | |
| MK-0752 | MK-0752 is a potent, orally active and specific ?-secretase inhibitor, showing dose-dependent reduction of A?40 with an IC50 of 5 nM in human SH-SY5Y cells. MK-0752 crosses the blood-brain barrier. MK-0752 reduces newly generated CNS A? in vivo[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 471905-41-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10974. | |
| MK-0752 | MK-0752 is a gamma secretase inhibitor in clinical development. Group: Biochemicals. Alternative Names: cis-4-[ (4-Chlorophenyl) sulfonyl]-4- (2, 5-difluorophenyl) cyclohexanepropanoic Acid. Grades: Highly Purified. CAS No. 471905-41-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| MK 0812 | MK 0812. Group: Biochemicals. Grades: Highly Purified. CAS No. 624733-88-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| MK-0822 | MK-0822 is a newly developed bone-targeting dual action pro-drug for osteoporosis and bone metastasis. It is also an inhibitor of cathepsin K, an enzyme involved in bone resorption. Group: Biochemicals. Alternative Names: N- (1-cyanocyclopropyl) -4-fluoro-N2-{ (1S) -2, 2, 2-trifluoro-1-[4'- (methylsulfonyl) biphenyl-4-yl]ethyl}-L-leucinamide, Odanacatib. Grades: Highly Purified. CAS No. 603139-19-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| MK 0893 | MK 0893 is a potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 870823-12-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50663. | |
| MK-1084 | MK-1084 is a selective KRAS G12C inhibitor that is currently in Phase I clinical trial (NCT05067283). MK-1084 exhibits anticancer activity and can be used either alone or in combination with pembrolizumab (HY-P9902) for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2641216-67-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-162431. | |
| MK 1903 | MK 1903. Group: Biochemicals. Grades: Purified. CAS No. 1268882-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK204 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MK-2048 | MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir. MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir. Group: Biochemicals. Alternative Names: (6S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N, 6-dimethyl-1, 9-dioxo-1, 2, 6, 7, 8, 9-hexahydropyrazino[1', 2':1, 5]pyrrolo[2, 3-d]pyridazine-4-carboxamide. Grades: Highly Purified. CAS No. 869901-69-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| MK 212 hydrochloride | MK 212 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 61655-58-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK-212 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MK-2206 | MK-2206 is an orally active, highly potent and selective allosteric Akt inhibitor, with IC 50 s of 8, 12, and 65 nM for Akt1, Akt2, and Akt3, respectively. Many breast cancer cell lines, and PIK3CA-mutant and cell lines with PTEN loss are sensitive to MK-2206. MK-2206 has anticancer activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1032349-77-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108232. | |
| MK-2206 | MK-2206 Inhibitor. Uses: Scientific use. Product Category: T1952. CAS No. 1032350-13-2. |  |
| MK-2206 (8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl[1, 2, 4]triazolo[3, 4-f][1, 6]naphthyridin-3(2H)-one Dihydrochloride) | A highly selective non-ATP competitive allosteric Akt inhibitor with IC??s of 8nM, 2nM and 65nM for Akt1, Akt2 and Akt3, respectively. MK-2206 potently inhibits phosphorylation of Thr308 and Ser473 in 3T3-L1 adipocytes with IC?? values of 0.11 and 0.18uM, respectively as well as downstream effects of insulin on GLUT4 translocation (IC?? = 0.47uM) and glucose transport (IC?? = 0.14uM). In addition, treatment with MK-2206 causes a robust, concentration-dependent activation of autophagy in human glioma cell lines LN229 and T98G. Group: Biochemicals. Grades: Highly Purified. CAS No. 1032350-13-2. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| MK-2206 dihydrochloride | MK-2206 dihydrochloride (MK-2206 (2HCl)) is an orally active, BBB-penetrated allosteric AKT inhibitor with IC 50 s of 5 nM, 12 nM, and 65 nM for AKT1 , AKT2 , and AKT3 , respectively. MK-2206 dihydrochloride induces autophagy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-2206 (2HCl). CAS No. 1032350-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10358. | |
| MK-2206 dihydrochloride | MK-2206 dihydrochloride. Group: Biochemicals. Alternative Names: 8-[4- (1-Aminocyclobutyl) phenyl]-9-phenyl-1, 2, 4-triazolo[3, 4-f][1, 6]naphthyridin-3 (2H) -one hydrochloride. Grades: Highly Purified. CAS No. 1032350-13-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C25H23Cl2N5O. US Biological Life Sciences. | Worldwide |
| MK-28 | MK-28 is a potent and selective PERK activator. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 864388-65-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-137207. | |
| MK2a Inhibitor - CAS 41179-33-3 | The MK2a Inhibitor, also referenced under CAS 41179-33-3, controls the biological activity of MK2a. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| MK-2 Dye | MK-2 Dye. Group: Organic solar cell (opv) materials. CAS No. 1037440-21-3. Product ID: (Z)-2-cyano-3-[5-[5-[5-[5-(9-ethylcarbazol-3-yl)-3-hexylthiophen-2-yl]-3-hexylthiophen-2-yl]-3-hexylthiophen-2-yl]-3-hexylthiophen-2-yl]prop-2-enoic acid. Molecular formula: 955.5g/mol. Mole weight: C58H70N2O2S4. CCCCCCC1=C (SC (=C1) C2=C (C=C (S2) C3=C (C=C (S3) C4=C (C=C (S4) C5=CC6=C (C=C5) N (C7=CC=CC=C76) CC) CCCCCC) CCCCCC) CCCCCC) C=C (C#N) C (=O) O. InChI=1S / C58H70N2O2S4 / c1-6-11-15-19-25-40-34-52 (63-50 (40) 38-45 (39-59) 58 (61) 62) 55-43 (27-21-17-13-8-3) 36-54 (65-55) 57-44 (28-22-18-14-9-4) 37-53 (66-57) 56-42 (26-20-16-12-7-2) 35-51 (64-56) 41-31-32-49-47 (33-41) 46-29-23-24-30-48 (46) 60 (49) 10-5 / h23-24, 29-38H, 6-22, 25-28H2, 1-5H3, (H, 61, 62) / b45-38-. FOELOZKDLHJOHT-JYRXYQGCSA-N. | |
| MK-2 Inhibitor III - CAS 1186648-22-5 | The MK-2 Inhibitor III, also referenced under CAS 1186648-22-5, controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| MK-2 Inhibitor IV, MK-25 | The MK-2 Inhibitor IV, MK-25 controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| MK-2 Inhibitor IV, MK-25 (MAPKAP-K2 Inhibitor IV, MK-25, 5-(4-Chlorophenyl)-N-(4-(piperazin-1-yl)phenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide, HCl) | A cell-permeable furanylcarboxamide compound that acts as a potent, reversible and non-ATP-competitive inhibitor of MK-2/MAPKAP-K2 activity (IC50=110nM; EC50=350nM for pHSP27 in IL-1b-stimulated SW1353 cells) with excellent selectivity over 150 kinases (% activity inhibition at 10uM against human CK2, Haspin, Arg and CK1y3=40, 40, 42 and >70, respectively). Shown to efficiently suppress the secretions of TNFa, IL6 (IC50=4.4 and 5.2uM in LPS-stimulated THP1 cell, respectively) and MMP-13 (IC50=5.7 and 2.2uM in IL1b-stimulated SW1353 and in primary osteoarthritis-derived chondrocytes, respectively). Exhibits desirable bioavailability and weakly inhibits a panel of cytochrome P450 isozymes (IC50>20uM for 3A4, 2D6 and 2C9). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MK-3207 | MK-3207 is an orally active, highly selective and species-specific CGRP receptor antagonist (for human CGRP receptor : IC 50 =0.12 nM; K i =0.024 nM). MK-3207 can be used for migraine studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 957118-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-10301. | |
| MK-3207 Hydrochloride | MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC 50 of 0.12 nM and K i of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3. Uses: Scientific research. Group: Signaling pathways. CAS No. 957116-20-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-10302. | |
| MK-4074 | MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1039758-22-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107709. | |
| MK-4256 | MK-4256 is a potent and selective SSTR3 antagonist with IC50s of 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1104599-69-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13466. | |
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