A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MA-5. CAS No. 1354707-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111536.
Mitochonic Acid 5
Mitochonic Acid 5 is a derivative of the plant hormone indole-3-acetic acid. It has been shown to improve survival of fibroblasts from patients with mitochondrial diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Mitochonic Acid 5; MA-5; MA 5; MA5. Product Category: Others. Appearance: Solid powder. CAS No. 1354707-41-7. Molecular formula: C18H13F2NO3. Mole weight: 329.3. Purity: >98%. IUPACName: 4-(2,4-Difluorophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid. Canonical SMILES: O=C(O)C(C1=CNC2=C1C=CC=C2)CC(C3=CC=C(F)C=C3F)=O. Product ID: ACM1354707417. Alfa Chemistry ISO 9001:2015 Certified.
mitogen-activated protein kinase
Phosphorylation of specific tyrosineand threonine residues in the activation loop of this enzyme by EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) is necessary for enzyme activation. Once activated, the enzyme phosphorylates target substrates on serine or threonine residues followed by a proline. A distinguishing feature of all MAPKs is the conserved sequence Thr-Xaa-Tyr (TXY). Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth...pk; PMK-1; PMK-2; PMK-3; pp42; pp44mapk; p44mpk; SAPK; STK26; stress-activated protein kinase. Enzyme Commission Number: EC 2.7.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3144; mitogen-activated protein kinase; EC 2.7.11.24; c-Jun N-terminal kinase; Dp38; ERK; ERK1; ERK2; extracellular signal-regulated kinase; JNK; JNK3α1; LeMPK3; MAP kinase; MAP-2 kinase; MAPK; MBP kinase I; MBP kinase II; microtubule-associated protein 2 kinase; microtubule-associated protein kinase; myelin basic protein kinase; p38Δ; p38-2; p42 mitogen-activated protein kinase; p42mapk; PMK-1; PMK-
Mitogen activated protein kinase from rat, Recombinant
Mitogen-activated protein kinases (MAPK) are protein kinases that are specific to the amino acids serine, threonine, and tyrosine. MAPKs belong to the CMGC (CDK/MAPK/GSK3/CLK) kinase group. MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. > 95% (sds-page), buffered aqueous glycerol solution, recombinant, expressed in e. coli (n-terminal histidine tagged). Group: Enzymes. Synonyms: ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Purity: > 95% (SDS-PAGE). MAP kinase. Mole weight: mol wt 42 kDa. Activity: > 500 U/mg. Stability: -70°C. Form: buffered aqueous glycerol solution. Source: E. coli. Species: Rat. ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Pack: vial of 100 ng. Cat No: NATE-0443.
mitogen-activated protein kinase kinase
This enzyme is a dual-specific protein kinase and requires mitogen-activated protein kinase kinase kinase (MAPKKK) for activation. It is required for activation of EC 2.7.11.24, mitogen-activated protein kinase. Phosphorylation of MEK1 by Raf involves phosphorylation of two serine residues. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth factor and platelet-derived growth factor), vasoactive peptides (e.g. angiotensin-II and endothelin), inflammatory cytokines of the tumour necrosis factor (TNF) family and environmental stresses such as osmotic shock, ionizing radiation and ischaemic injury. Group: Enzymes. Synonyms: MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK . Enzyme Commission Number: EC 2.7.12.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3162; mitogen-activated protein kinase kinase; EC 2.7.12.2; MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK kinase; MAP2K; MAPKK; MAPKK1; MEK; MEK1; MEK2; MKK; MKK2; MKK4; MKK6; MKK7; STK27. Cat No: EXWM-3162.
mitogen-activated protein kinase kinase kinase
This enzyme phosphorylates and activates its downstream protein kinase, EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) but requires MAPKKKK for activation. Some members of this family can be activated by p21-activated kinases (PAK/STE20) or Ras. While c-Raf and c-Mos activate the classical MAPK/ERK pathway, MEKK1 and MEKK2 preferentially activate the c-Jun N-terminal protein kinase(JNK)/stress-activated protein kinase (SAPK) pathway. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e...mes. Synonyms: cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Enzyme Commission Number: EC 2.7.11.25. CAS No. 146702-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3145; mitogen-activated protein kinase kinase kinase; EC 2.7.11.25; 146702-84-3; cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Cat No: EXWM-3145.
Mitogenic Pentapeptide
Mitogenic Pentapeptide represents a potent activator for monocytes/macrophages and B lymphocytes. Synonyms: Tripalmitoyl pentapeptide; Bppp-cssaa; P3C-Ssna; Pam3Cys-ser-ser-asn-ala; 2,3-Bis(palmitoyloxy)propyl-N-palmitoylpentapeptide. CAS No. 87173-03-3. Molecular formula: C67H124N6O14S. Mole weight: 1269.80.
Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG. CAS No. 459-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-106634.
Mito-LND
Mito-LND (Mito-Lonidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS). Mito-LND inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mito-Lonidamine. CAS No. 2361564-49-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134832.
mitomycin 6-O-methyltransferase
The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B. Group: Enzymes. Synonyms: MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Enzyme Commission Number: EC 2.1.1.316. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1924; mitomycin 6-O-methyltransferase; EC 2.1.1.316; MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Cat No: EXWM-1924.
Mitomycin A
Mitomycin A is a bacterial metabolite. Mitomycin A reduces migration inhibition factor ( MIF ) production and can be used for the research of cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 4055-39-4. Pack Sizes: 500 μg. Product ID: HY-130332.
Mitomycin A
Mitomycin A is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity B; Mitiromycin B. Grade: > 95%. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34.
Mitomycin B
Mitomycin B is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity C; (1aS)-8α-[[(Aminocarbonyl)oxy]methyl]-1,1aα,2,8,8aα,8bα-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxyazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [1aS-(1aalpha,8alpha,8aalpha,8balpha)]-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grade: > 95%. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34.
Mitomycin C
Mitomycin C is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. And it has an inhibitory effect on tumors. Uses: Mitomycin c is also available as a a 4% mixture in nacl. see "mitomycin c+nacl" sample coa. Synonyms: Mitiromycin E; Mutamycin; Ametycine; Zilimeisu. Grade: Assay ≥ 970 mg/g Mitomycin. CAS No. 50-07-7. Molecular formula: C15H18N4O5. Mole weight: 334.33.
Mitomycin C
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-25mg. Molecular Weight 334.33. See USA prepack pricing.
Mitomycin C
2mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-2mg. Molecular Weight 334.33. See USA prepack pricing.
Mitomycin C
An antitumor antibiotic. It is used as antineoplastic. Group: Biochemicals. Alternative Names: [1aS-(1aα,8 β , 8aα , 8bα ) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; MMC; Ametycine; Mutamycin; Mitonco; Mitoplus. Grades: Highly Purified. CAS No. 50-07-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Mitomycin C-[13C,d3]
An isotope labelled Mitomycin C, which is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells. Synonyms: Mitomycin C-13C,d3; ((1aS,8S,8aR,8bS)-6-Amino-8a-methoxy-5-(methyl-13C-d3)-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl)methyl carbamate. Grade: > 95%. Molecular formula: C14[13C]H15D3N4O5. Mole weight: 338.34.
Mitomycin C Pure (NaCl-Free)
Supplied as a pure preparation of Mitomycin C. This preparation contains no sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 4mg, 12mg, 24mg, 40mg. US Biological Life Sciences.
Worldwide
Mitomycin C w/NaCl
Supplied as a preparation of Mitomycin C with sodium chloride in a ratio of 2mg Mitomycin C and 48mg sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 2mg. US Biological Life Sciences.
Worldwide
Mitomycin D
Mitomycin D. Group: Biochemicals. Alternative Names: (1aS, 8R, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-hydroxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Highly Purified. CAS No. 10169-34-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C15H18N4O5. US Biological Life Sciences.
Worldwide
Mitomycin D
Mitomycin D is a mito-mycin antibiotic produced by Streptomyces caespitosus with anti-tumor activity. It is also a semi-synthetic antibiotic with anti-leukemic properties. Uses: An antitumor antibiotic. it is used as antineoplastic. Synonyms: 7-Demethoxy-7-aminomitomycin B; (1aS,8R,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [(1aS,8S,8aR,8bS)-6-Amino-8a-hydroxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methylcarbamate; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,5-dimethyl-8a-hydroxy-, (1aS-(1a-α,8-β,8a-α,8b-α))-; BRN 4720574; NSC 123106. Grade: 95%. CAS No. 10169-34-3. Molecular formula: C15H18N4O5. Mole weight: 334.33.
Mitonafide
A Naphthalimides with potent anticancer activity. Group: Biochemicals. Alternative Names: 2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benz[de]isoquinoline-1,3(2H)-dione. Grades: Highly Purified. CAS No. 54824-17-8. Pack Sizes: 25mg. US Biological Life Sciences.
A cell-permeable, thiazolidinedione (TZD) that acts as an inhibitor of MitoNEET (IC50=0.9uM) in competition with rosiglitazone and pioglitazone, in liver mitochondrial suspensions. In pharmacological studies, it was found to alter isolated mitochondrial complex I respiration with an IC50 of 2.4uM and inhibited State III respiration up to 45%. Furthermore, this compound (6-25uM) is shown to dose-dependently reduce lactate-dehydrogenase release in SH-SY5Y cultures, leading to a 40% decrease in rotenone-induced cell-death. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
MitoPerOx
MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1392820-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125623.
MitoPQ
MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MitoParaquat. CAS No. 1821370-28-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130278.
Mitoquinol
Mitoquinol is a mitochondrial-targeted coenzyme Q analog. Mitoquinol is an antioxidant that inhibits lipid peroxidation. Mitoquinol can be used in vascular disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845959-55-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124410.
Mitoquinone mesylate
Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant in order to protect against oxidative damage [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MitoQ mesylate; MitoQ10 mesylate. CAS No. 845959-50-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100116A.
Mito Red
suitable for fluorescence, ?70% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Mitoridine
Mitoridine. Group: Biochemicals. Grades: Plant Grade. CAS No. 3911-19-1. Pack Sizes: 10mg. Molecular Formula: C20H22N2O2, Molecular Weight: 322.4. US Biological Life Sciences.
Worldwide
Mitorubrin
Mitorubrin is a metabolite synthesized by phytotoxic fungi. Synonyms: (-)-Mitorubrin; β-Resorcylic acid, 6-methyl-, ester with 7-hydroxy-7-methyl-3-propenyl-6H-2-benzopyran-6,8(7H)-dione (7CI,8CI). CAS No. 3403-71-2. Molecular formula: C21H18O7. Mole weight: 382.36.
Mitorubrinic acid
Mitorubrinic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 58958-07-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H16O9. US Biological Life Sciences.
Worldwide
MitoSOX Red
MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red. Excitation/emission wavelength: 510/580 nm. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1003197-00-9. Pack Sizes: 50 ?g; 100 ?g; 500 ?g. Product ID: HY-D1055.
Mitotane
Mitotane. Group: Biochemicals. Grades: Highly Purified. CAS No. 53-19-0. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C14H10Cl4. US Biological Life Sciences.
Worldwide
Mitotane
Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,4-DDD; o,p'-DDD. CAS No. 53-19-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13690.
Mitotane
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
An Antineoplastic. Used as an adrenolytic agent. Group: Biochemicals. Alternative Names: o,p'-DDD, CB-313, Lysodren,1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic with superoxide and alkyl radical scavenging properties[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334850-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112879.
MitoTEMPO hydrate
Mito-TEMPO is a mitochondria-targeted antioxidant that possesses superoxide and alkyl radical scavenging properties. Mito-TEMPO helps protect against oxidative damage to the mitochondria [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1569257-94-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125944.
MitoTEMPOL
MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2 - to H2O2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1101113-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-115386.
MitoTracker Deep Red FM
MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 644/665 nm[1]. MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm[2].The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: MTDR FM. CAS No. 873315-86-7. Pack Sizes: 50 ?g; 100 ?g. Product ID: HY-D1783.
MitoTracker Green FM
Mito-Tracker Green is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm. Uses: Scientific research. Group: Fluorescent dye. CAS No. 201860-17-5. Pack Sizes: 50 ?g. Product ID: HY-135056.
Mitoxantrone
Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; 1, 4-Bis [ (2- (2- hydroxyethylamino) ethyl) amino] -5, 8-di hydroxyanthraquinone. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Mitoxantrone
50mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6. CAS No. 65271-80-9. Prepack ID 28035650-50mg. Molecular Weight 444.48. See USA prepack pricing.
Mitoxantrone
Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity [1] [2] [3] [4]. Mitoxantrone also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone; NSC 301739. CAS No. 65271-80-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502.
An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
A DNA intercalating drug. Inhibits DNA synthesis. Used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Mitoxantrone dihydrochloride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6 · 2HCl. CAS No. 70476-82-3. Prepack ID 24343907-1g. Molecular Weight 517.4. See USA prepack pricing.
Mitoxantrone dihydrochloride
Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity [1] [2] [3] [4]. Mitoxantrone dihydrochloride also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride. CAS No. 70476-82-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502A.
Mitoxantrone dihydrochloride
It is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating and antineoplastic anthraquinone derivative. Synonyms: 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione dihydrochloride; DHAQ; CL-232325; CL 232325; CL232325; Novantrone; Mitroxone; Neotalem; Onkotrone; Pralifan; Mitoxantrone 2HCl; Immunex. Grade: >98%. CAS No. 70476-82-3. Molecular formula: C22H28N4O6.2HCl. Mole weight: 517.40.
Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione Hydrochloride; Bisantrone; CL 232315; DHAD; Immunex; Mitoxantrone Hydrochloride; NCI 301739; NSC 301739; Novantron; Novantrone; Novatrone. Grades: Highly Purified. CAS No. 70476-82-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Mitoxantrone hydrochloride
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dione dihydrochloride,Mitoxantrone hydrochloride.
Mitoxantrone Impurity4
Mitoxantrone Impurity4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 100204-25-9. Molecular formula: C24H28ClF3N4O7. Mole weight: 576.95. Catalog: APB100204259.
Mitoxantrone Liposome
Mitoxantrone is an anthracycline that enters the nucleus of the cell and binds to DNA, thereby inhibiting nucleic acid synthesis and mitosis, leading to cell death. This product is a pre-formulated liposome with mitoxantrone. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
Mitoxantrone System Suitability Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Mitragynine
Mitragynine is an indole alkaloid from the plant M. speciosa. It has stimulatory, antinociceptive, and opiate-like effects, acting through noradrenergic, serotonergic, and opioid receptors.1,2 Mitragynine has a higher affinity for the μ-opioid receptor than the δ- or κ-opioid receptors (pKi = 8.14, 7.22, and 5.96, respectively).2 Mitragynine and its derivatives have been identified in products sold as incense.3 The identification and quantification of mitragynine and related alkaloids, as well as their phase I and II metabolites, have been described.4-6 This product is intended for forensic applications.This product is qualified as a Reference Material that has been manufactured and tested to ISO/IEC 17025 and ISO 17034 international standards. Group: Biochemicals. Alternative Names: (αE,2S,3S,12bS)-3-Ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic Acid Methyl Ester; (-)-Mitragynine; 9-Methoxy-corynantheidine; 16,17-Didehydro-9,17-dimethoxy-corynan-16-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 4098-40-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?O?, Molecular Weight: 398.5. US Biological Life Sciences.
Worldwide
Mitragynine-D3 solution
100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Hallucinogens standards.
Mitraphylline
Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils [1]. Uses: Scientific research. Group: Natural products. CAS No. 509-80-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6946.
Mitraphylline
Mitraphylline is an alkaloid isolated from Uncaria rhynchophylla anti-inflammatory activity and inhibiting lipopolysaccharide-mediated activation of primary human neutrophils. Synonyms: Mitraphilline. Grade: 98%. CAS No. 509-80-8. Molecular formula: C21H24N2O4. Mole weight: 368.43.
Mivacurium
Mivacurium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133814-19-4. Molecular formula: C58H80N2O142+. Mole weight: 1029.28. Catalog: APB133814194.
Mivacurium Chloride
Mivacurium Chloride. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106861-44-3. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.18. Catalog: APB106861443.
Mivacurium Chloride Impurity 11
Mivacurium Chloride Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104758-51-2. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.18. Catalog: APB104758512.
Mivacurium Chloride Impurity 12
Mivacurium Chloride Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107740-63-6. Molecular formula: C58H80Cl2N2O14. Mole weight: 1100.18. Catalog: APB107740636.