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| Product | Description | |
|---|---|---|
| Mst-312 | MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Telomerase Inhibitor IX, MST-312, CHEMBL2170856, N,N-bis(2,3-Dihydroxybenzoyl)-1,3-phenylenediamine, 368449-04-1, CTK1B6051, IN1063, ZINC03937611, AG-F-28784, Benzamide, N,N-1,3-phenylenebis[2,3-dihydroxy-, N,N inverted exclamation marka-1,3-Phenylenebis-[2,3-dihydroxy-benzamide]. Product Category: Inhibitors. Appearance: Solid. CAS No. 368449-04-1. Molecular formula: C20H18N2O6. Mole weight: 382.37. Purity: ≥95%. IUPACName: N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide. Canonical SMILES: C1=CC(=CC(=C1)NC(=O)C2=C(C(=CC=C2)O)O)NC(=O)C3=C(C(=CC=C3)O)O. Product ID: ACM368449041. Alfa Chemistry ISO 9001:2015 Certified. Categories: Mt. 3:12. |  |
| MST-312 | MST-312 is an inhibitor of telomerase, an enzyme responsible for telomere maintenance in almost all human cancer cells. MST-312 showed cytotoxic action and promoted telomere erosion, senescence, and chromosome aberrations in a small proportion. Study has shown that MST312 inhibited replication of HSV, interfering the life cycle of virus. Synonyms: Telomerase Inhibitor IX; N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide. Grades: ≥98%. CAS No. 368449-04-1. Molecular formula: C20H16N2O6. Mole weight: 380.35. |  |
| MST-312 | MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Telomerase Inhibitor IX. CAS No. 368449-04-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120145. |  |
| MST-312 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| MSTFA Reagent | ampule of 10 × 1.2 mL, analytical standard. Group: Certified reference materials (crms). | |
| MSU38225 | MSU38225 is an Nrf-2 inhibitor that increases levels of reactive oxygen species (ROS). MSU38225 inhibits the growth of human lung cancer cells and enhances the sensitivity of human lung cancer cells to chemotherapy in vitro and in vivo. MSU38225 can be used in cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1629160-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153873. | |
| MSX-122 | MSX-122 is a novel small molecule and partial CXCR4 antagonist. Synonyms: MSX122; MSX 122; MSX-122. N-[[4-[ (pyrimidin-2-ylamino) methyl]phenyl]methyl]pyrimidin-2-amine. CAS No. 897657-95-3. Molecular formula: C16H16N6. Mole weight: 292.34. | |
| MSX-3 hydrate | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| MT1 | MT1 is a bivalent chemical probe of BET bromodomains , with an IC 50 of 0.789 nM for BRD4(1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2060573-82-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111976. | |
| MT-1207 | MT-1207 is an orally active and selective adrenergic α 1 and 5-HT 2A receptor antagonist. MT-1207 shows IC 50 <0.1 nM, 0.15 nM, 1.40 nM and 0.27 nM for α 1A , α 1B , α 1D and 5-HT 2A , respectively. MT-1207 achieves an effective blood pressure (BP) reduction in the 2K2C rat model without damaging renal function. MT-1207 is a potent multitarget inhibitor with the potential for vasodilatation research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1610794-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162677. | |
| MT1-MMP Inhibitor, NSC405020 | The MT1-MMP Inhibitor, NSC405020 controls the biological activity of MT1-MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. | |
| MT1-MMP Inhibitor, NSC405020 (3,4-Dichloro-N-(1-methylbutyl)benzamide, 3,4-Dichloro-N-(pentan-2-yl)benzamide) | A cell-permeable pentanylbenzamide compound that acts as an allosteric, reversible, and selective inhibitor of the collgenolytic activity of MT1-MMP. Does not affect the catalytic activity of cellular MT-1-MMP thus allows it to retain its ability to activate MMP-2. Selectively targets the hemopexin (PEX) domain of MT1-MMP, thereby repressing its pro-tumorigenic activity. Its binding to the PEX domain is dependent on Met-328, Arg-330, Asp-376, Met-422, and Ser-470 in the druggable pocket of the enzyme. Shown to block 184B5-MT cell migration on collagen-1 and repress MCF7-b3/MT tumor growth in xenografted mice (0.5mg/kg, intratumoral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| MT-4 | MT-4 is a derivative of a tissue transglutaminase ( TG2 ) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel. Uses: Scientific research. Group: Signaling pathways. CAS No. 2327925-35-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128595. | |
| MT477 | MT477 is PKC-α inhibitor. MT477 interfered with PKC activity as well as phosphorylation of Ras and ERK1/2 in H226 human lung carcinoma cells. It also induced poly-caspase-dependent apoptosis. MT477 had a dose-dependent (0.006 to 0.2 mM) inhibitory effect on cellular proliferation of H226, MCF-7, U87, LNCaP, A431 and A549 cancer cell lines as determined by in vitro proliferation assays. Synonyms: MT 477; MT-477; tetramethyl 6'-[(2,5-dioxopyrrolidin-1-yl)acetyl]-7'-methoxy-5',5'-dimethyl-5',6'-dihydrospiro[1,3-dithiole-2,1'-thiopyrano[2,3-c]quinoline]-2',3',4,5-tetracarboxylate. CAS No. 328069-91-6. Molecular formula: C31H30N2O12S3. Mole weight: 718.77. | |
| MT 81 | MT 81 is a plant toxin that comes from Penicillum nigricans. It has anti-Gram-positive bacteria activity. Synonyms: Mycotoxin 81; Mycotoxin MT 81; MT81; BRN 4596898; 1,5-Dihydroxy-3-methyl-8-[(2,6,7,7a-tetrahydro-4H-furo[3,2-c]pyran-4-yl)oxy]-9,10-anthracenedione. CAS No. 93513-59-8. Molecular formula: C22H18O7. Mole weight: 394.37. | |
| MTBD | MTBD (CAS# 84030-20-6 ) is a useful research chemical. Synonyms: 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene; 1,3,4,6,7,8-Hexahydro-1-methyl-2H-pyrimido[1,2-a]pyrimidine; 1-Methyl-2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine; 2H-Pyrimido[1,2-a]pyrimidine,1,3,4,6,7,8-hexahydro-1-methyl-; mTBD. Grades: 95 %. CAS No. 84030-20-6. Molecular formula: C8H15N3. Mole weight: 153.22. | |
| MTBSTFA (with 1% t-BDMCS) | ampule of 5 × 1 mL, (with 1% t-BDMCS), analytical standard. Group: Certified reference materials (crms). | |
| MTBT | MTBT is an anticancer agent and p38 activator with antiproliferative and apoptosis-inducing ( apoptosis ) activities. MTBT increases the phosphorylation of histone H3 serine in cancer cells, thereby arresting the cell cycle in the M phase. SB203580 (HY-10256), a specific inhibitor of p38 MAPK, abolished MTBT-induced cell cycle arrest [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1110905-26-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118034. | |
| MT-DADMe-ImmA | MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with a Ki of 90 pM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTDIA; Methylthio-DADMe-Immucillin A. CAS No. 653592-04-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101496. | |
| MTDIA | MTDIA is a human 5'-methylthioadenosine phosphorylase (MTAP) inhibitor, which is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. It is used as an anticancer candidate. Synonyms: Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium. Grades: 98%. CAS No. 653592-04-2. Molecular formula: C13H19N5OS. Mole weight: 294.35. | |
| MTDIA hydrochloride | MTDIA is a methylthioadenosine phosphorylase (MTAP) inhibitor. MTAP is responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer drug candidates and MTDIA is one of these TS analogues. Uses: Anticancer drug candidate. Synonyms: (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium chloride; MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl. Grades: 98%. CAS No. 1399840-35-7. Molecular formula: C13H20ClN5OS. Mole weight: 329.85. | |
| MTEP | Potent and selective antagonist for mGluR5. 5-fold higher anxiolytic activity than MPEP. Antidepressant. Neuroprotective. Produces anti-parkinsonian-like effects in rats. Group: Biochemicals. Alternative Names: 3-pyridine. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C11H8N2S. US Biological Life Sciences. | Worldwide |
| MTEP hydrochloride | Glutamate, the major excitatory neurotransmitter in the brain, acts on both ionotropic and metabotropic glutamate receptors. Excessive metabotropic glutamate receptor (mGluR) transmission has been linked to epilepsy, ischemia, pain, anxiety, and depression. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol pathway, while Group II (2 and 3) and Group III (4, 6, 7, and 8) inhibit adenylyl cyclase. MTEP is a negative allosteric modulator of the mGlu5a receptor subtype (Ki = 42 nM; IC50=110 nM). MTEP at 0.3 mg/kg produces antidepressant effects in several rodent models of depression. It also demonstrates neuroprotective potential by preventing excitotoxic neuronal damage when administered through either intrahippocampal or intraperitoneal injection. Additionally, MTEP demonstrates an anxiolytic-like phenotype in rodent models similar to that of benzodiazepines while lacking undesirable sedative and addictive effects. Synonyms: 3-((2-Methyl-1,3-thiazol-4-yl)ethyn-yl)pyridine hydrochloride; MTEP. Grades: >98%. CAS No. 1186195-60-7. Molecular formula: C11H9ClN2S. Mole weight: 236.72. | |
| MTEP hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MTEP hydrochloride | MTEP hydrochloride is a potent, non-competitive and highly selective mGluR5 antagonist, with an IC 50 of 5 nM and a K i of 16 nM. MTEP hydrochloride shows antidepressant and anxiolytic-like effects. MTEP hydrochloride can be used for Parkinson's disease research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1186195-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13206. | |
| MTEP Hydrochloride | MTEP Hydrochloride. Group: Biochemicals. Alternative Names: 3-[ (2-Methyl-4-thiazolyl) ethynyl]pyridine; 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Hydrochloride. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 10mg. Molecular Formula: C11H9ClN2S, Molecular Weight: 236.72. US Biological Life Sciences. | Worldwide |
| MTEP Hydrochloride (3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine Hydrochloride) | A non-competitive, potent antagonist highly selective for mGlu5 receptors (IC50 = 5nM). Biologically active admitted orally or systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1186195-60-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| m-Terphenyl | m-Terphenyl (CAS# 92-06-8) is a useful research chemical. Synonyms: 1,1':3',1''-Terphenyl; m-Diphenylbenzene; meta-terphenyl. Grades: 99 %. CAS No. 92-06-8. Molecular formula: C18H14. Mole weight: 230.30. | |
| m-Terphenyl | analytical standard. Group: Volatile & semivolatile standards. | |
| M-Terphenyl | M-terphenyl is a yellow solid. mp: 86-87° C, bp: 365°C. Density: 1.195 g/cm³. Insoluble in water. Usually shipped as a solid mixture with its isomers o-terphenyl and p-terphenyl that is used as a heat-transfer fluid.;Colorless or light-yellow solid.;Yellow solid (needles). Group: Pressure & heat sensitive recording materials carbon nano materials. Alternative Names: m-Diphenylbenzene. CAS No. 92-06-8. Product ID: 1,3-Diphenylbenzene. Molecular formula: 230.3. Mole weight: C18H14. C1=CC=C (C=C1)C2=CC (=CC=C2)C3=CC=CC=C3. InChI=1S/C18H14/c1-3-8-15 (9-4-1)17-12-7-13-18 (14-17)16-10-5-2-6-11-16/h1-14H. YJTKZCDBKVTVBY-UHFFFAOYSA-N. 99%. |  |
| m-Terphenyl-2'-ol | m-Terphenyl-2'-ol. Group: Small molecule semiconductor building blocks. CAS No. 2432-11-3. Product ID: 2,6-diphenylphenol. Molecular formula: 246.3g/mol. Mole weight: C18H14O. C1=CC=C (C=C1)C2=C (C (=CC=C2)C3=CC=CC=C3)O. InChI=1S/C18H14O/c19-18-16 (14-8-3-1-4-9-14)12-7-13-17 (18)15-10-5-2-6-11-15/h1-13, 19H. ATGFTMUSEPZNJD-UHFFFAOYSA-N. | |
| M-Terphenyl-5'-Yltrimethylsilane | M-Terphenyl-5'-Yltrimethylsilane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (3,5-diphenylphenyl)-trimethylsilane; (M-Terphenyl-5-yl)triMethylsilane; 3,5-Diphenyl-1-trimethylsilylbenzene. Product Category: Alkyl Silane. Appearance: Transparent liquid. CAS No. 128388-53-4. Molecular formula: C21H22Si. Mole weight: 302.48. Purity: 95%+. IUPACName: (3,5-diphenylphenyl)-trimethylsilane. Density: 1.02g/cm³. Product ID: ACM128388534. Alfa Chemistry ISO 9001:2015 Certified. | |
| mTERT (572-580) | A peptide fragment of mTERT. Mouse telomerase reverse transcriptase (mTERT) is a gene that is expressed by cells that need to continually divide without the characteristic shortening of telomeres that accompanies DNA replication. Synonyms: hTERT R572Y peptide; Mouse telomerase reverse transcriptase (572-580). | |
| Mth-dl-alanine | Mth-dl-alanine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MTH-DL-ALANINE;MTH-DL-Alanine Methylthiohydantoin-DL-alanine;4H-Imidazol-4-one,2,3-dihydro-3,5-dimethyl-2-thioxo-(9CI). Product Category: Heterocyclic Organic Compound. CAS No. 64948-74-9. Molecular formula: C5H8N2OS. Mole weight: 144.19. Product ID: ACM64948749. Alfa Chemistry ISO 9001:2015 Certified. | |
| M-theraphotoxin-Gr1a | This cationic hydrophobic peptide inhibits a lot of different channels and has an antimicrobial activity. It also exhibits antimicrobial activities against the Gram-positive bacteria B.subtilis (MIC=0.5 μM), S.aureus (MIC=2-4 μM), and S.epidermidis (MIC=4-8 μM), and Gram-negative bacteria S.typhimurium (MIC=32.64 μM), P.aeruginosa (MIC=8-16 μM), and E.coli (MIC=8-16 μM). Synonyms: M-TRTX-Gr1a; GsMTx-4. | |
| MTHPA (Methyl Tetrahydrophthalic Anhydride) | MTHPA (Methyl Tetrahydrophthalic Anhydride). Group: Epoxy resins. | |
| m-threo-chloramphenicol | m-threo-chloramphenicol. Group: Biochemicals. Alternative Names: Dichloro-N-[2-hydroxy-1- (hydroxymethyl) -2- (3-nitrophenyl) ethyl]acetamide. Grades: Highly Purified. CAS No. 7411-65-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C11H12Cl2N2O5. US Biological Life Sciences. | Worldwide |
| MTIC | MTIC is a metabolite Temozolomide, which is an alkylating drug. Synonyms: 5-(3-Methyl-1-triazeno)imidazole-4-carboxamide. CAS No. 3413-72-7. Molecular formula: C5H8N6O. Mole weight: 168.16. | |
| MTIC | MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3413-72-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119696. | |
| MTIC-d3 (Monomethyl-d3 Triaizeno Imidazole Carboxamide, 3-Methyl-d3-(triazenyl)imidazole-4-carboxamide, 5-(3-Methyl-d3-triazen-1-yl)imidazole-4-carboxamide, NSC 407347-d3) | A labeled metabolite of Temozolomide, an antineoplastic. Group: Biochemicals. Alternative Names: Monomethyl-d3 Triaizeno Imidazole Carboxamide; 3-Methyl-d3-(triazenyl)imidazole-4-carboxamide; 5-(3-Methyl-d3-triazen-1-yl)imidazole-4-carboxamide; NSC 407347-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MTIC (Monomethyl Triaizeno Imidazole Carboxamide) | A metabolite of Temozolomide, an antineoplastic. Group: Biochemicals. Alternative Names: Monomethyl Triaizeno Imidazole Carboxamide; 3-Methyl (triazenyl)imidazole-4-carboxamide; 5- (3-Methyltriazen-1-yl)imidazole-4-carboxamide, NSC 407347. Grades: Highly Purified. CAS No. 3413-72-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| MTK458 | MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinson's disease[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EP-0035985. CAS No. 2499962-58-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152943. | |
| m-Tolidine | m-Tolidine. Group: Monomerspolymers. CAS No. 84-67-3. Product ID: 4-(4-amino-2-methylphenyl)-3-methylaniline. Molecular formula: 212.29g/mol. Mole weight: C14H16N2. CC1=C(C=CC(=C1)N)C2=C(C=C(C=C2)N)C. InChI=1S/C14H16N2/c1-9-7-11 (15)3-5-13 (9)14-6-4-12 (16)8-10 (14)2/h3-8H, 15-16H2, 1-2H3. QYIMZXITLDTULQ-UHFFFAOYSA-N. | |
| m-Tolualdehyde | m-Tolualdehyde (3-Methylbenzaldehyde) is a compound that can be isolated from Ficus carica L. and Myosotis arvensis. m-Tolualdehyde has food protective effects. m-Tolualdehyde shows acaricidal activities for Tyrophagus putrescentiae with a LD 50 of 1.97?μg/cm 3 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Methylbenzaldehyde. CAS No. 620-23-5. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-78086. | |
| m-Toluic acid | 1kg Pack Size. Group: Building Blocks, Organics. Formula: C8H8O2. CAS No. 99-04-7. Prepack ID 90029790-1kg. Molecular Weight 136.15. See USA prepack pricing. |  |
| m-Toluic acid | 500g Pack Size. Group: Building Blocks, Organics. Formula: C8H8O2. CAS No. 99-04-7. Prepack ID 90029790-500g. Molecular Weight 136.15. See USA prepack pricing. | |
| m-Toluic Acid | M-toluic acid appears as white to yellowish crystals or mostly yellow flaky solid (with some white flakes). Has a floral-honey odor. (NTP, 1992);DryPowder; PelletsLargeCrystals. Group: Polymers. Product ID: 3-methylbenzoic acid. Molecular formula: 136.15g/mol. Mole weight: C8H8O2. CC1=CC(=CC=C1)C(=O)O. InChI=1S/C8H8O2/c1-6-3-2-4-7 (5-6)8 (9)10/h2-5H, 1H3, (H, 9, 10). GPSDUZXPYCFOSQ-UHFFFAOYSA-N. | |
| M-Toluic acid | M-Toluic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 99-04-7. Pack Sizes: 500g, 1kg, 2kg, 5kg. Molecular Formula: C8H8O2. US Biological Life Sciences. | Worldwide |
| m-Toluidine | m-Toluidine. Group: Biochemicals. Alternative Names: 3-Methylaniline. Grades: Highly Purified. CAS No. 108-44-1. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: CH3C6H4NH2. US Biological Life Sciences. | Worldwide |
| m-Toluidine hydrochloride | m-Toluidine hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: M-TOLUIDINE HYDROCHLORIDE;3-methylanilinehydrochloride;3-methylbenzenaminehydrochloride;3-methyl-benzenaminhydrochloride;m-toluidiniumchloride;m-ToluidineHCl;META-TOLUIDINEHYDROCHLORIDE;3-Toluidine Hydrochloride. Product Category: Heterocyclic Organic Compound. Appearance: Light gray solid. CAS No. 638-03-9. Molecular formula: C7H10ClN. Mole weight: 143.61. Product ID: ACM638039. Alfa Chemistry ISO 9001:2015 Certified. | |
| m-Toluquinoline | m-Toluquinoline. Group: Biochemicals. Alternative Names: 7-Methyl-quinoline; 7-Methylquinoline; NSC 65665. Grades: Highly Purified. CAS No. 612-60-2. Pack Sizes: 2.5g. Molecular Formula: C9H10N, Molecular Weight: 143.19. US Biological Life Sciences. | Worldwide |
| m-Tolyl acetate | m-Tolyl acetate. Group: Biochemicals. Alternative Names: Acetic acid 3-methylphenyl ester. Grades: Highly Purified. CAS No. 122-46-3. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C9H10O2. US Biological Life Sciences. | Worldwide |
| m-Tolylboronic acid MIDA ester | m-Tolylboronic acid MIDA ester. Group: Salt. | |
| m-Tolylmagnesium chloride solution | 1.0 M in THF. Group: Organometallic reagents. | |
| m-Tolylurea | m-Tolylurea. Group: Biochemicals. Grades: Highly Purified. CAS No. 63-99-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| m-Topolin | m-Topolin. Group: Biochemicals. Alternative Names: 6- (3-Hydroxybenzylamino) purine. Grades: Highly Purified. CAS No. 75737-38-1. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C12H11N5O. US Biological Life Sciences. | Worldwide |
| m-Topolin-9-glucoside | m-Topolin-9-glucoside is a powerful compound with potent anti-inflammatory attributes, warranting its utilization in the research of afflictions like rheumatoid arthritand inflammatory bowel disease. Synonyms: 6-(3-hydroxybenzylamino)-9-b-D-glucopyranosyl purine. CAS No. 179528-30-4. Molecular formula: C18H21N5O6. Mole weight: 403.39. | |
| m-Topolin riboside | m-Topolin riboside, an esteemed compound employed in the realm of biomedical research, unveils remarkable possibilities in combatting a myriad of ailments, ranging from cancer to neurological disorders. Its intricate composition and distinctive mode of operation engender a plethora of revitalizing attributes, particularly in terms of thwarting tumor progression and safeguarding neural integrity. Synonyms: N6-(3-Hydroxybenzyl)adenosine; 6-(3-Hydroxybenzylamino)-9-b-D-ribofuranosylpurine; Adenosine, N-[(3-hydroxyphenyl)methyl]-; N-(3-Hydroxybenzyl)adenosine. Grades: ≥ 98% (HPLC). CAS No. 110505-76-5. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| m-Topolin riboside-5'-monophosphate salt | m-Topolin riboside-5'-monophosphate salt is a remarkable and groundbreaking compound, aiding in the research of diverse diseases. By impeding the proliferation of malignant cells and triggering programmed cell death, this extraordinary compound exhibits its inhibition in studying cancer. Synonyms: 6-(3-Hydroxybenzylamino)-9-b-D-ribofuranosylpurine-5'-monophosphate disodium monohydrate; N6-(3-Hydroxybenzyl)adenosine-5'-monophosphate. CAS No. 946853-27-6. Molecular formula: C17H18N5Na2O8P·H2O. Mole weight: 515.32. | |
| mTOR Activator, MHY1485 (4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine, Autophagy Inhibitor III) | A cell-permeable triazine derivative that is shown to increase cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation level in rat liver Ac2F cells (1 to 2uM for 1h), affecting culture viability only at much higher concentrations (by 20% after 24h 20uM treatment). MHY1485 induced cellular LC3-II accumulation in Ac2F is reported to be a result of autophagy inhibition due to reduced fusion between autophagosomes and lysosomes. The mechanism of mTOR activation by MHY1485 is currently unknown. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| mTOR-IN-1 | Selective inhibitors of mammalian target of rapamycin (mTOR) kinase based upon saturated heterocycles fused to a pyrimidine core were designed and synthesized. Each series produced compounds with Ki < 10 nM for the mTOR kinase and>500-fold selectivity over closely related PI3 kinases. This potency translated into strong pathway inhibition, as measured by phosphorylation of mTOR substrate proteins and antiproliferative activity in cell lines with a constitutively active PI3K pathway. Two compounds exhibiting suitable mouse PK were profiled in in vivo tumor models and were shown to suppress mTORC1 and mTORC2 signaling for over 12 h when dosed orally. Both compounds were additionally shown to suppress tumor growth in vivo in a PC3 prostate cancer model over a 14 day study. Synonyms: mTOR-IN-1; mTOR IN 1. Grades: >98%. CAS No. 1207358-59-5. Molecular formula: C25H30N8O2. Mole weight: 474.56. | |
| mTOR inhibitor-1 | mTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 468747-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112914. | |
| mTOR inhibitor-3 | mTOR inhibitor-3 is a remarkably selective mTOR inhibitor with a Ki of 1.5 nM. mTOR inhibitor-3 suppresses mTORC1 and mTORC2 in cellular and in vivo pharmacokinetic (PK)/pharmacodynamic (PD) experiments. Uses: Scientific research. Group: Signaling pathways. CAS No. 1207358-59-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18353. | |
| mTOR Inhibitor III, PP242 | The mTOR Inhibitor III, PP242 controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| mTOR Inhibitor IV, Ku-63794 - CAS 938440-64-3 | The mTOR Inhibitor IV, Ku-63794, also referenced under CAS 938440-64-3, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| mTOR Inhibitor, Ku-0063794 (rel-5- [2- [ (2R, 6S) -2, 6-Dimethyl-4-morpholinyl] -4- (4-morpholinyl) pyrido [2, 3-d] pyrimidin-7-yl] -2-methoxy Benzene methanol) | A potent mTOR (mammalian target of rapamycin) inhibitor (IC?? =~10nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested. Group: Biochemicals. Grades: Highly Purified. CAS No. 938440-64-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| mTOR Inhibitor XII, Torin2 (9- (6-aminopyridin-3-yl) -1- (3- (trifluoromethyl) phenyl) benzo[h][1, 6]naphthyridin-2 (1H) -one, DNA-PK Inhibitor VII, PI 3-K Inhibitor XIX, PI 4-K Inhibitor) | A Torin1 structural analog that acts as a cell-permeable, potent, ATP-competitive inhibitor against DNA-PK and mTOR (IC50 = 0.5 and 2.81nM, respectively). Comparing to Torin1, Torin2 displays enhanced inhibitory potency against PI 4-Kbeta (IC50 = 18.3nM) and PI 3-K (IC50 =4.68, 5.67, 8.58, 17.5, 24.5, and 28.1nM, respectively, against P110alpha/P85alpha, P110-gamma, hVPS34, P110delta/P85alpha, C2beta, C2alpha, respectively), while being more effective in inhibiting S6K1 Thr389 phosphorylation in MEF cultures (IC50 = 0.25nM vs 2nM, respectively, for Torin2 and Torin1) in vitro and displaying much improved oral bioavailability in mice (Cmax (ng/mL) /T1/2 (h) = 3968/0.72 and 223/0.79, respectively, for Torin2 and Torin1; 10/mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O, Primary Target: MTOR. US Biological Life Sciences. | Worldwide |
| mTOR Inhibitor XI, Torin1 (1- (4- (4-propionylpiperazin-1-yl) -3- (trifluoromethyl) phenyl) -9- (quinolin-3-yl) benzo[h][1, 6]naphthyridin-2 (1H) -one, DNA-PK Inhibitor VI, PI 3-K Inhibitor XVIII) | A cell-permeable pyridinonequinoline derivative that acts as a highly potent, ATP-competitive inhibibitor against mTOR and DNA-PK (IC50 = 4.32 and 6.34nM, respectively), while inhibiting PI 3-K only at much higher concentrations (IC50 =171 to 533nM). Effectively inhibits mTORC1-mediated S6K1 phosphorylation in MEF (IC50 = 2nM) in vitro, as well as mTORC2-mediated Akt and mTORC1-dependent S6 phosphorylations in murine lung and liver in vivo (up to 6h post single 20mg/kg i.p. dose). Despite its poor in vivo stability (T1/2 = 4.52h in mice; 10mg/kg i.p.), Torin1 is reported to completely suppress U87MG-derived tumor expansion in mice when administered via daily i.p. at a high dosage of 200mg/kg. Also reported to effectively inhibit cellular mTORC1 functionalities known to be rapamycin-resistant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| mTOR Kinase Inhibitor II, WYE-354 - CAS 1062169-56-5 | The mTOR Kinase Inhibitor II, WYE-354, also referenced under CAS 1062169-56-5, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| mTOR/Raptor/MLST8 human | recombinant, expressed in baculovirus infected Sf9 cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
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