A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
MS-681a, originally isolated from Myrothecium sp. KY6568, is a myosin light chain kinase (MLCK) inhibitor (IC50=0.11 μmol/L). CAS No. 173485-72-8. Molecular formula: C61H91N13O9. Mole weight: 1150.45.
MSA-2
An orally available non-nucleotide STING agonist, with EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. Grades: >98%. CAS No. 294425-81-6. Molecular formula: C14H14O5S. Mole weight: 294.32.
MSAB is a potent and selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin and promotes its degradation, and specifically downregulates Wnt/β-catenin target genes. MSAB exhibits potent anti-tumor effects selectively on Wnt-dependent cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173436-66-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120697.
MSAB
MSAB is a Wnt/β-catenin signaling inhibitor. It has selective and potent anti-tumor effects on Wnt-dependent cancer cells. MSAB binds to β-catenin, promotes its degradation, and specifically down-regulates Wnt/β-catenin target genes. Grades: 98%. CAS No. 173436-66-3. Molecular formula: C15H15NO4S. Mole weight: 305.4.
m-Salicylic Acid is widely used in organic synthesis. It is also an important active metabolite of aspirin (A187780). Group: Biochemicals. Alternative Names: 3-Hydroxybenzoic Acid; 3-Carboxyphenol; NSC 55746; m-Carboxyphenol; m-Hydroxybenzoic Acid. Grades: Highly Purified. CAS No. 99-06-9. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
MSB-2311
MSB-2311 is a second-generation programmed cell death 1 ligand 1 (PD-L1) antibody with pH-dependent antigen binding property. The pH-dependent antigen binding property allows recycle of MSB-2311 in tumor cells and much longer residence time. Studies show that MSB-2311 is active in multiple tumor models. Uses: Pd-l1 antibody. Synonyms: Betifisolimab; MSB-2311; MSB 2311; MSB2311. CAS No. 2460539-60-8.
MSBN
MSBN is a highly selective fluorogenic probe for thiols. MSBN can be used to image thiols in live cells selectively and specifically label protein thiols with a signal to determine various reversible protein thiol modifications [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 135980-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119493.
MSC-2032964A acts as a selective apoptosis signal-regulating kinase 1(ASK1) inhibitor suppressing neuroinflammation with IC50 value of 93 nM in mice. It blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. It suppresses neuroinflammation in a mouse EAE model. It is orally bioavailable and brain penetrant. Synonyms: MSC2032964A; MSC 2032964A; N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide; N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide; 3-Pyridinecarboxamide, N-[5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-. Grades: >98%. CAS No. 1124381-43-6. Molecular formula: C16H13F3N6O. Mole weight: 362.32.
MSC2530818
MSC2530818 is a specific and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8. Synonyms: MSC2530818; MSC-2530818; MSC 2530818. [(2S)-2-(4-chlorophenyl)pyrrolidin-1-yl]-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)methanone; SCHEMBL17514257; s8387; AKOS032946259. CAS No. 1883423-59-3. Molecular formula: C18H17ClN4O. Mole weight: 340.81.
MSC-4381
MSC-4381 (MCT4-IN-1) is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC 50 of 77 nM and a K i of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research [1]. MSC-4381 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCT4-IN-1. CAS No. 2445185-57-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132301.
MSD-819 is extracted from Streptomycess ambofaciens. It has anti-gram-positive and anti-gram-negative bacteria activity. Synonyms: 2-Quinoxalinecarboxylicacid, 6-chloro-, 1,4-dioxide; 3-Carboxy-7-chloro-1-oxoquinoxalin-1-ium-4(1H)-olate. CAS No. 22587-15-1. Molecular formula: C9H5ClN2O4. Mole weight: 240.60.
MSD-92
It is originally isolated from Actinomyces sp. MSD-92 has anti-gram-positive and anti-gram-negative activity, and the MIC of it against Escherichia coli was 2 μg/mL. Synonyms: 2-Methylfervenulone; BRN 0540815; 2,8-Dihydro-2,6,8-trimethylpyrimido(5,4-e)-as-triazine-3,5,7-trione. CAS No. 22712-32-9. Molecular formula: C8H9N5O3. Mole weight: 223.19.
MSDC 0160
MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimers disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mitoglitazone; CAY10415. CAS No. 146062-49-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100550.
MSDC-0160
MSDC-0160 reduces resistance in the insulin/IGF-1 signaling pathway and restores IGF-1-induced Akt and GSK-3 phosphorylation. Synonyms: Mitoglitazone; CAY10415; 5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione; Pioglitazone Ketone; 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione; 5-{4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione. Grades: >98%. CAS No. 146062-49-9. Molecular formula: C19H18N2O4S. Mole weight: 370.42.
MSDC-0602
MSDC-0602 is an insulin sensitizer that has the potential to treat diabetes and other inflammatory diseases. It exhibits low affinity for binding and activation of PPAR&gamma. Synonyms: MSDC-0602; MSDC0602; MSDC 0602; 5-{4-[2-(3-Methoxyphenyl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]methyl]-. CAS No. 1133819-87-0. Molecular formula: C19H17NO5S. Mole weight: 371.407.
Msdh-c
Msdh-c. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D-ERYTHRO-1-METHYLTHIOHYDROCERAMIDE;(2R,3R)-(2-N-LAUROYL)-AMINO-1-METHYLTHIO-3-HYDROXYNONAN;MSDH-C. Product Category: Heterocyclic Organic Compound. Appearance: White to off-white powder. CAS No. 144474-37-3. Molecular formula: C22H45NO2S. Mole weight: 387.66. Product ID: ACM144474373. Alfa Chemistry ISO 9001:2015 Certified. Categories: MS Dhoni.
MSG606
MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1416983-77-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1726.
MSG 606
MSG 606 is a potent human MC1 receptor antagonist (IC50 = 17 nM), and also partial agonist at human MC3 and MC5 receptors (EC50= 59 and 1300 nM, respectively). Synonyms: MSG 606; MSG606; MSG-606. CAS No. 1416983-77-1. Molecular formula: C62H82N20O13S. Mole weight: 1347.51.
MSI-1436
MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B) , with an IC 50 of appr 1 μM, 200-fold preference over TCPTP (IC 50 , 224 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trodusquemine; Aminosterol-1436. CAS No. 186139-09-3. Pack Sizes: 500 μg. Product ID: HY-12219.
MSI-1436 lactate
MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B ( PTP1B ), with an IC 50 of 1 μM, 200-fold preference over TCPTP ( IC 50 of 224 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trodusquemine lactate; Aminosterol-1436 lactate. CAS No. 1309370-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12219A.
MSI-594
MSI-594 is a highly active AMP with a broad-spectrum of activities against bacteria, fungi, and virus.
mSiTrz
mSiTrz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Phenyl-4,6-bis(3-(triphenylsilyl)phenyl)-1,3,5-triazine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2252416-90-1. Molecular formula: C57H43N3Si2. Mole weight: 826.14 g/mol. Product ID: ACM2252416901. Alfa Chemistry ISO 9001:2015 Certified. Categories: Mistrzejowice.
Msk-195
Msk-195. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SureCN93984, CTK8E9625, MSK-195, 289902-82-5. Product Category: Heterocyclic Organic Compound. Appearance: White solid. CAS No. 289902-82-5. Molecular formula: C28H40N2O5. Mole weight: 484.6. Purity: 0.96. IUPACName: [2-[[[2-[4-(2-aminoethoxy)-3-methoxyphenyl]acetyl]amino]methyl]-3-(3,4-dimethylphenyl)propyl] 2,2-dimethylpropanoate. Product ID: ACM289902825. Alfa Chemistry ISO 9001:2015 Certified.
MSNBA is a specific inhibitor of GLUT5 fructose transport in proteoliposomes. MSNBA competitively inhibits GLUT5 fructose uptake with a K I of 3.2±0.4 μM in MCF7 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 852702-51-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W179181.
Msop
Msop. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MSOP;(RS)-ALPHA-METHYLSERINE-O-PHOSPHATE;(R,S)-a-Methylserine-O-phosphate. Product Category: Heterocyclic Organic Compound. CAS No. 66515-29-5. Molecular formula: C4H10NO6P. Mole weight: 199.1. Product ID: ACM66515295. Alfa Chemistry ISO 9001:2015 Certified.
MSOP
MSOP. Group: Biochemicals. Grades: Purified. CAS No. 66515-29-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MSOP
MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent K D of 51 μM for the L-AP4-sensitive presynaptic mGluR. Uses: Scientific research. Group: Signaling pathways. CAS No. 66515-29-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101226.
MSOP
MSOP is a selective group III metabotropic glutamate receptor (mGluR) antagonist. MSOP exhibits an apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. MSOP has no effect on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons. Synonyms: (RS)-α-Methylserine-O-phosphate; Alpha-MSOP; Alpha-methylserine-O-phosphate; 2-amino-2-methyl-3-phosphonooxypropanoic acid. CAS No. 66515-29-5. Molecular formula: C4H10NO6P. Mole weight: 199.1.
MSP-3
MSP-3 is a potent TRPV1 agonist, with an EC 50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820968-63-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118785.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CMG↑CKG GKC↓GMC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Storage at -70°C is recommended for periods longer than 30 days. Form: Liquid. Source: Moraxella species A1. Pack: 20 mM Tris-HCl (pH 7.6); 300 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 10 mM MgCl2, 200 μg/ml BSA, 50% glycerol. Cat No: ET-1140RE.
MSPC
MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose. Uses: Scientific research. Group: Natural products. Alternative Names: PC(14:0/18:0); 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine. CAS No. 76343-22-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W019833.
MS-PEG3-t-butyl ester
MS-PEG3-t-butyl ester. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 1312309-62-8. Molecular formula: C12H24O7S. Mole weight: 312.38. Purity: 95%+. Product ID: ACM1312309628. Alfa Chemistry ISO 9001:2015 Certified. Categories: Mes-PEG2-acid t-butyl ester.
MS-PEG4-MS
MS-PEG4-MS. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 55400-73-2. Molecular formula: C10H22O9S2. Mole weight: 350.41. Purity: 95%+. Product ID: ACM55400732. Alfa Chemistry ISO 9001:2015 Certified.
MS-PEG4-THP
MS-PEG4-THP. Uses: Designed for use in research and industrial production. Product Category: Other PEG Linkers. CAS No. 145927-73-7. Molecular formula: C14H28O8S. Mole weight: 356.43. Purity: 95%+. Product ID: ACM145927737. Alfa Chemistry ISO 9001:2015 Certified.
MSPG
MSPG is a non-selective antagonist of presynaptic mGluRs. Synonyms: (RS)-α-Methyl-4-sulfonophenylglycine; MSPG; (RS)-MSPG; 2-amino-2-(4-sulfophenyl)propanoic acid. CAS No. 169209-64-7. Molecular formula: C9H11NO5S. Mole weight: 245.25.
MSPG
MSPG. Group: Biochemicals. Grades: Purified. CAS No. 169209-64-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Msp I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑CGG GGC↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Moraxella species. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1139RE.
MS-PPOH
MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. It potently inhibits two CYP450 epoxygenases CYP2C9 and CYP2C11 (IC50 = 11-16 μM). Synonyms: N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide. Grades: ≥98%. CAS No. 206052-02-0. Molecular formula: C16H21NO4S. Mole weight: 323.4.
MspR9 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold mspr9 i overdigestion >5% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CC↑NGG GGN↓CC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Micrococcus species R9. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoetyanol; 100 μg/ml BSA; and 50% glycerol. Cat No: ET-1141RE.
Msr-Ratio (Msr-green) is a ratiometric fluorescent probe of methionine sulfoxide reductase (λex=375 nm, λem=550 nm). Msr-Ratio is used for monitoring the enzyme activity in vitro and in live cells [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Msr-green. CAS No. 2290635-22-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1257.
MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Telomerase Inhibitor IX, MST-312, CHEMBL2170856, N,N-bis(2,3-Dihydroxybenzoyl)-1,3-phenylenediamine, 368449-04-1, CTK1B6051, IN1063, ZINC03937611, AG-F-28784, Benzamide, N,N-1,3-phenylenebis[2,3-dihydroxy-, N,N inverted exclamation marka-1,3-Phenylenebis-[2,3-dihydroxy-benzamide]. Product Category: Inhibitors. Appearance: Solid. CAS No. 368449-04-1. Molecular formula: C20H18N2O6. Mole weight: 382.37. Purity: ≥95%. IUPACName: N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide. Canonical SMILES: C1=CC(=CC(=C1)NC(=O)C2=C(C(=CC=C2)O)O)NC(=O)C3=C(C(=CC=C3)O)O. Product ID: ACM368449041. Alfa Chemistry ISO 9001:2015 Certified. Categories: Mt. 3:12.
MST-312 is an inhibitor of telomerase, an enzyme responsible for telomere maintenance in almost all human cancer cells. MST-312 showed cytotoxic action and promoted telomere erosion, senescence, and chromosome aberrations in a small proportion. Study has shown that MST312 inhibited replication of HSV, interfering the life cycle of virus. Synonyms: Telomerase Inhibitor IX; N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide. Grades: ≥98%. CAS No. 368449-04-1. Molecular formula: C20H16N2O6. Mole weight: 380.35.
MT1 is a bivalent chemical probe of BET bromodomains , with an IC 50 of 0.789 nM for BRD4(1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2060573-82-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111976.
MT-1207
MT-1207 is an orally active and selective adrenergic α 1 and 5-HT 2A receptor antagonist. MT-1207 shows IC 50 <0.1 nM, 0.15 nM, 1.40 nM and 0.27 nM for α 1A , α 1B , α 1D and 5-HT 2A , respectively. MT-1207 achieves an effective blood pressure (BP) reduction in the 2K2C rat model without damaging renal function. MT-1207 is a potent multitarget inhibitor with the potential for vasodilatation research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1610794-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162677.
MT1-MMP Inhibitor, NSC405020
The MT1-MMP Inhibitor, NSC405020 controls the biological activity of MT1-MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable pentanylbenzamide compound that acts as an allosteric, reversible, and selective inhibitor of the collgenolytic activity of MT1-MMP. Does not affect the catalytic activity of cellular MT-1-MMP thus allows it to retain its ability to activate MMP-2. Selectively targets the hemopexin (PEX) domain of MT1-MMP, thereby repressing its pro-tumorigenic activity. Its binding to the PEX domain is dependent on Met-328, Arg-330, Asp-376, Met-422, and Ser-470 in the druggable pocket of the enzyme. Shown to block 184B5-MT cell migration on collagen-1 and repress MCF7-b3/MT tumor growth in xenografted mice (0.5mg/kg, intratumoral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
MT-4
MT-4 is a derivative of a tissue transglutaminase ( TG2 ) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel. Uses: Scientific research. Group: Signaling pathways. CAS No. 2327925-35-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128595.
MT477
MT477 is PKC-α inhibitor. MT477 interfered with PKC activity as well as phosphorylation of Ras and ERK1/2 in H226 human lung carcinoma cells. It also induced poly-caspase-dependent apoptosis. MT477 had a dose-dependent (0.006 to 0.2 mM) inhibitory effect on cellular proliferation of H226, MCF-7, U87, LNCaP, A431 and A549 cancer cell lines as determined by in vitro proliferation assays. Synonyms: MT 477; MT-477; tetramethyl 6'-[(2,5-dioxopyrrolidin-1-yl)acetyl]-7'-methoxy-5',5'-dimethyl-5',6'-dihydrospiro[1,3-dithiole-2,1'-thiopyrano[2,3-c]quinoline]-2',3',4,5-tetracarboxylate. CAS No. 328069-91-6. Molecular formula: C31H30N2O12S3. Mole weight: 718.77.
MT 81
MT 81 is a plant toxin that comes from Penicillum nigricans. It has anti-Gram-positive bacteria activity. Synonyms: Mycotoxin 81; Mycotoxin MT 81; MT81; BRN 4596898; 1,5-Dihydroxy-3-methyl-8-[(2,6,7,7a-tetrahydro-4H-furo[3,2-c]pyran-4-yl)oxy]-9,10-anthracenedione. CAS No. 93513-59-8. Molecular formula: C22H18O7. Mole weight: 394.37.
MTBD
MTBD (CAS# 84030-20-6 ) is a useful research chemical. Synonyms: 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene; 1,3,4,6,7,8-Hexahydro-1-methyl-2H-pyrimido[1,2-a]pyrimidine; 1-Methyl-2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine; 2H-Pyrimido[1,2-a]pyrimidine,1,3,4,6,7,8-hexahydro-1-methyl-; mTBD. Grades: 95 %. CAS No. 84030-20-6. Molecular formula: C8H15N3. Mole weight: 153.22.
MTBT is an anticancer agent and p38 activator with antiproliferative and apoptosis-inducing ( apoptosis ) activities. MTBT increases the phosphorylation of histone H3 serine in cancer cells, thereby arresting the cell cycle in the M phase. SB203580 (HY-10256), a specific inhibitor of p38 MAPK, abolished MTBT-induced cell cycle arrest [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1110905-26-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118034.
MTDIA
MTDIA is a human 5'-methylthioadenosine phosphorylase (MTAP) inhibitor, which is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. It is used as an anticancer candidate. Synonyms: Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium. Grades: 98%. CAS No. 653592-04-2. Molecular formula: C13H19N5OS. Mole weight: 294.35.
MTDIA hydrochloride
MTDIA is a methylthioadenosine phosphorylase (MTAP) inhibitor. MTAP is responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer drug candidates and MTDIA is one of these TS analogues. Uses: Anticancer drug candidate. Synonyms: (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium chloride; MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl. Grades: 98%. CAS No. 1399840-35-7. Molecular formula: C13H20ClN5OS. Mole weight: 329.85.
MTEP
Potent and selective antagonist for mGluR5. 5-fold higher anxiolytic activity than MPEP. Antidepressant. Neuroprotective. Produces anti-parkinsonian-like effects in rats. Group: Biochemicals. Alternative Names: 3-pyridine. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C11H8N2S. US Biological Life Sciences.